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Meconium evacuation in newborn

Maria Boczar, Ewa Sawicka, Katarzyna Zybert
AIM: Evaluation of diagnostic and treatment procedures in children with cystic fibrosis (CF) operated on because of meconium ileus (MI). MATERIAL AND METHODS: The authors retrospectively reviewed the documentation of 10 CF newborn patients operated on in the years 2000-2014 because of MI. In prenatal ultrasound (US) examinations, suspicion of bowel abnormalities was raised in 2 cases, even though all the 10 mothers had a minimum of 3 US examinations during pregnancy...
January 2015: Developmental Period Medicine
Michael H Livingston, Anna C Shawyer, Peter L Rosenbaum, Connie Williams, Sarah A Jones, J Mark Walton
BACKGROUND AND OBJECTIVE: Premature infants are often given glycerin enemas or suppositories to facilitate meconium evacuation and transition to enteral feeding. The purpose of this study was to assess the available evidence for this treatment strategy. METHODS: We conducted a systematic search of Medline, Embase, Central, and trial registries for randomized controlled trials of premature infants treated with glycerin enemas or suppositories. Data were extracted in duplicate and meta-analyzed using a random effects model...
June 2015: Pediatrics
Patricia Mena N, Jorge León Del P, Daniela Sandino P, Pamela Ralmolfo B, Debora Sabatelli, Adolfo Llanos M, Beatriz Milet L
INTRODUCTION: It has been reported that feeding tolerance in preterm infants is associated with an early passage of meconium. Prospective, randomized or historical control studies that stimulate meconium evacuation have reported varied results. This study was intented to evaluate the use of enemas to speed up meconium evacuation, facilitating feeding tolerance. PATIENTS AND METHOD: A controlled multicenter randomized trial that evaluated the use of physiological saline enemas with glycerol (0...
June 2014: Revista Chilena de Pediatría
Mu-Xue Yu, Si-Qi Zhuang, Dan-Hua Wang, Xiao-Yu Zhou, Xiao-Hong Liu, Li-Ping Shi, Shao-Jie Yue, Ji-Hong Qian, Jian-Hua Sun
OBJECTIVE: To study the effects of extensively hydrolyzed protein formula (eHF) on the feeding and growth in preterm infants through a multicenter controlled clinical study. METHODS: Preterm infants admitted to eight upper first-class hospitals in China between February 2012 and December 2013 were randomly selected. They were divided into two observation groups and two control groups. The first observation group consisted of preterm infants with a gestational age of <32 weeks, who were fed with eHF for 10-14 days after birth and then with standard preterm formula (SPF) until discharge...
July 2014: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
Hee Sun Kim, Bo-Kyung Je, Sang Hoon Cha, Byung Min Choi, Ki Yeol Lee, Seung Hwa Lee
BACKGROUND: When abdominal distention occurs or bowel obstruction is suspected in the neonatal period, a water-soluble contrast enema is helpful for diagnostic and therapeutic purposes. The water-soluble contrast medium is evacuated through the anus as well as excreted via the kidneys in some babies. This study was designed to evaluate the incidence of renal excretion after enemas using water-soluble contrast media and presume the causes. METHODS: Contrast enemas using diluted water-soluble contrast media were performed in 23 patients under 2 months of age...
August 2014: Pediatrics and Neonatology
Sema Rala Tanriverdi, Tuncer Turhan, Ozgun Uygur, Ozge Altun Koroglu, Mehmet Yalaz, Nilgun Kultursay
Intracerebellar hemorrhage is very rare in term infants and only severe cases with massive intracranial hemorrhage, posthemorrhagic hydrocephalus and clinical deterioration due to increased intracranial pressure require neurosurgical evacuation. In recent adult studies endoscopic hematoma evacuation has been shown as a rapid, effective, and safe technique. A term newborn hospitalized for meconium aspiration syndrome showed hypertonia, jitteriness and abnormal amplitude integrated electroencephalogram findings...
October 2013: Brain & Development
Nadja Haiden, Florentine Norooz, Kathrin Klebermass-Schrehof, Anna Sophie Horak, Bernd Jilma, Angelika Berger, Andreas Repa
OBJECTIVE: To determine whether enteral application of the osmotic contrast agent Gastrografin accelerates complete meconium excretion and improves feeding tolerance in very low birth weight infants. METHODS: This study was a stratified, randomized, placebo-controlled trial in premature infants with a birth weight <1500 g and a gestational age <32 weeks who received 3 mL/kg Gastrografin diluted 1:3 with water within their first 24 hours of life, or placebo...
December 2012: Pediatrics
R Núñez-Ramos, M A Fabbro, M González-Velasco, R Núñez Núñez, B Romanato, L Vecchiato, S D'Agostino, E Blesa Sánchez
INTRODUCTION: The objective of this study was to determine the normal anal position index (API) in neonates and in a group of older children with chronic constipation, and to identify the incidence of anterior ectopic anus (AEA) in the two groups. MATERIALS AND METHODS: A prospective random study was carried out in two European hospitals determining the API in 1,012 neonates (529 in Group A, and 483 in Group B) and in 64 children suffering chronic constipation of ages between 3 months and 12 years (Group C)...
October 2011: Pediatric Surgery International
V Zanardo, P Gamba, C Menti, D Trevisanuto
AIM: Meconium obstruction has been viewed as a cause of bowel dysfunction and poorer outcome in preterm neonates. This study investigated whether the need of meconium induction over the 7th postnatal day would relate with later bowel habit development. The study was carried out at the Department of Pediatrics, University of Padua, Italy. METHODS: This was a prospective study, performed on 80 premature infants, separately analyzed in three subgroups according to the gestational ages (Subgroup A [16]: 23-26/6; Subgroup B [26]: 27/0-30/6; and Subgroup C [38]: 31/0-34/6 weeks), after the induction from 7th day of life of meconium evacuation by saline enema...
December 2010: Minerva Pediatrica
So-Yeon Shim, Han-Suk Kim, Do-Hyun Kim, Ee-Kyung Kim, Dong Woo Son, Beyong Il Kim, Jung-Hwan Choi
BACKGROUND: A delay in reaching full enteral feeding is linked to poorer outcome in preterm neonates. Meconium retention has been viewed as a cause of bowel dysfunction in very low birth weight infants (VLBWI). Thus, adequate evacuation of meconium could help to promote feeding tolerance. OBJECTIVES: Our goal was to determine the effect of the induction of early meconium evacuation on feeding tolerance in VLBWI. METHODS: An observational study involving two subsequent periods was performed in inborn infants with birth weights of <1,500 g, before (control) and after (study) the induction of early meconium evacuation by routine glycerin enema...
2007: Neonatology
Nadja Haiden, Bernd Jilma, Bernadette Gerhold, Katrin Klebermass, Andrea R Prusa, Stefan Kuhle, Klaudia Rohrmeister, Christina Kohlhauser-Vollmuth, Arnold Pollak
We hypothesized that small volume enemas accelerate meconium evacuation in very low birth weight (VLBW) infants. In a randomized controlled trial, VLBW infants (n = 81) received either repeated daily small volume enemas if complete spontaneous meconium passage failed within 24 h or no intervention. Small volume enemas did not accelerate complete meconium evacuation, which occurred after 6.0 to 9.6 (95% CI) d in the intervention group and after 7.7 to 11.0 (95% CI) d in the control group. No adverse events were observed...
February 2007: Journal of Pediatric Gastroenterology and Nutrition
Somchai Thepcharoennirund
Primary fascial closure of gastroschisis remains controversial. Some surgeons routinely place a prosthetic silo over the exposed bowel, planning a staged closure. From August 1987 to August 2004, 129 cases of gastroschisis were treated at the Pediatric Surgical Unit, Department of Surgery, Ratchaburi Hospital. There were 61 boys and 68 girls. One hundred and seven mothers were primigravida. Associated anomalies were present in 13 patients. One hundred and twelve patients underwent primary fascial closure. The success of this technique depends on enlarging the abdominal cavity and decreasing the volume of the bowel that must be replaced in the peritoneal cavity...
April 2005: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
David Bader, Yoav Yanir, Amir Kugelman, Mira Wilhelm-Kafil, Arieh Riskin
This prospective randomized trial evaluated the effect of induction of early meconium evacuation on neonatal jaundice in healthy term neonates. The study group was given glycerin suppository immediately after birth and every 4 hours thereafter, until evacuation of first stool. Glycerin suppository caused faster meconium evacuation but had no effect on mean bilirubin levels at 48 hours. However, males had significantly lower mean bilirubin levels, especially if they also had type A blood group. Glycerin suppository cannot be routinely recommended as a means for reducing the severity of neonatal jaundice...
August 2005: American Journal of Perinatology
Sherif Emil, Thang Nguyen, Jack Sills, Guadalupe Padilla
BACKGROUND: Guidelines for diagnosis and therapy of meconium obstruction in extremely low birth weight neonates are still not well established. METHODS: All low-birth-weight infants presenting with meconium obstruction over a 5-year period were reviewed retrospectively. Patients with meconium plug syndrome or cystic fibrosis were excluded. RESULTS: Seven patients were identified. Average birth weight and gestational age were 874 g and 27.7 weeks, respectively...
May 2004: Journal of Pediatric Surgery
W A Mihatsch, A R Franz, W Lindner, F Pohlandt
UNLABELLED: The aim of this study was to evaluate the correlation between the timing of the first and last meconium and feeding tolerance in the very early enteral nutrition of extremely low birthweight (ELBW) infants. Forty-one ELBW infants were fed following a standardized protocol (day 3-14). At 48 h of age bolus gavage feeding with milk was started (12 ml kg(-1) d(-1) increments, 12 meals per day). Gastric residuals up to 2 ml or up to 3 ml were tolerated in infants with a birthweight of < or = 750 g or > 750 g, respectively...
April 2001: Acta Paediatrica
G Z Mak, F J Harberg, P Hiatt, A Deaton, R Calhoon, M L Brandt
BACKGROUND/PURPOSE: The T-tube ileostomy was first used at Texas Children's Hospital in 1959. The purpose of this study is to update the experience since the initial report of this technique in 1981. METHODS: A database of 448 patients with cystic fibrosis (CF) seen in the authors' institution was used to identify 83 patients (18.5%) who presented with meconium ileus. The clinic and hospital charts of these patients were reviewed retrospectively to identify patients who had undergone placement of a T-tube ileostomy...
February 2000: Journal of Pediatric Surgery
I H Krasna, D Rosenfeld, P Salerno
Failure of a small premature newborn to adequately evacuate meconium for days or weeks has been attributed to "probable necrotizing enterocolitis (NEC)" or "microcolon of prematurity." The authors present an unusual type of "meconium plug syndrome" with the same clinical picture, seen in tiny premature babies (500 to 1,500 g), which required a contrast enema or Gastrografin upper gastrointestinal (UGI) series to evacuate the plugs. The obstruction resolved. Twenty babies (480 to 1,500 g) presented with the same clinical picture without any x-ray suggestion of NEC; contrast enemas were performed because of the suspicion of meconium plug syndrome...
June 1996: Journal of Pediatric Surgery
E M Salariya, C M Robertson
The incidence of neonatal jaundice is reported to have increased in relation to breast feeding and various factors are thought to contribute to this either singularly or in concert. In a group of 150 full-term healthy babies, feeding types and gut transit time of meconium were examined. The findings demonstrated significant differences between feeding types and time taken to evacuate total meconium (p < 0.0001), weight loss/gain patterns (p < 0.0005) and the incidence of moderately severe jaundice (p < 0...
December 1993: Midwifery
M Ries, K H Deeg
We report on a patient with atresia of the colon transversum and a large meconium pseudocyst adherent to the liver. Sonography additionally revealed multiple cystic structures due to intrahepatic meconium masses. Surgical evacuation of the meconium pseudocyst resulted in massive diffuse hemorrhage from the liver which could not be stopped. The child died intraoperatively due to hemorrhagic shock. Histologically the intrahepatic meconium masses were surrounded by various degrees of necrosis and hemorrhage without a well-defined capsule of fibrous granulation tissue...
November 1994: Acta Paediatrica
J Y Chen, U P Ling, J H Chen
Delayed passage of meconium may increase enterohepatic circulation of bilirubin, which appears to be an important contributor to neonatal jaundice. To evaluate the effect of early meconium evacuation on neonatal hyperbilirubinemia, between January 1993 and December 1993, 265 healthy neonates were studied and randomly divided into two groups. Group 1 consisted of 130 neonates who received glycerin enema (1 mL of glycerin mixed with 1 mL of warmed normal saline) within 30 minutes after birth and the same procedure was repeated at 12 hours of age...
July 1995: American Journal of Perinatology
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