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https://www.readbyqxmd.com/read/29149258/edge-to-edge-repair-for-mitral-regurgitation-associated-with-isolated-double-orifice-mitral-valve
#1
Takeshi Oda, Takanori Kono, Keiichi Akaiwa, Katsuhiko Nakamura
We report the case of a patient with severe mitral regurgitation who was diagnosed with double-orifice mitral valve by preoperative transthoracic and transoesophageal echocardiography. During surgery, it was revealed that the mitral valve was divided into 2 orifices, anterolateral and posteromedial, by a fibrous bridging tissue that was supported by the chordae tendineae originating from an accessory middle papillary muscle. The posterior scallop of the anterolateral orifice was prolapsed due to chordal elongation...
November 15, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29147460/corrigendum-to-identification-of-patients-affected-by-mitral-valve-prolapse-with-severe-regurgitation-a-multivariable-regression-model
#2
Paola Songia, Benedetta Porro, Mattia Chiesa, Veronika Myasoedova, Francesco Alamanni, Elena Tremoli, Paolo Poggio
[This corrects the article DOI: 10.1155/2017/6838921.].
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29122631/mitral-valve-prolapse-multimodality-imaging-and-genetic-insights
#3
REVIEW
Purvi Parwani, Jean-Francois Avierinos, Robert A Levine, Francesca Nesta Delling
Mitral valve prolapse (MVP) is a common heritable valvulopathy affecting approximately 2.4% of the population. It is the most important cause of primary mitral regurgitation (MR) requiring surgery. MVP is characterized by fibromyxomatous changes and displacement of one or both mitral leaflets into the left atrium. Echocardiography represents the primary diagnostic modality for assessment of MVP. Accurate quantitation of ventricular volumes and function for surgical planning in asymptomatic severe MR can be provided with both echocardiography and cardiac magnetic resonance ...
November 6, 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29110750/aortic-elasticity-and-carotid-intima-media-thickness-in-children-with-mitral-valve-prolapse
#4
Elif Erolu, Figen Akalın, Nilüfer Çetiner, Berna Şaylan Çevik
Aim We aimed to study the dimensions, systolic and diastolic functions of the left ventricle; dimensions and elasticity of the aorta; and carotid intima-media thickness and flow-mediated dilatation of the brachial artery in mitral valve prolapse. METHODS: The study group consisted of 43 patients (mean age=13.3±3.9) and 42 healthy children (mean age=12.9±3.4). Left ventricular end-diastolic, end-systolic, left atrial diameters, interventricular septum, and left ventricular posterior wall thickness were measured...
November 7, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/29095710/emergency-valve-replacement-under-minimal-cardiopulmonary-bypass-for-a-patient-with-infective-endocarditis-and-large-brain-hematoma-a-case-report
#5
Gabor Kiss, Eric Braunberger
A 19-year-old man with mitral valve endocarditis and prolapse, intracerebral and intracerebellar hematoma, and a mycotic cerebral aneurysm underwent emergency mitral valve replacement during minimal cardiopulmonary bypass (total priming volume, 800 mL; autologous retropriming, activated clotting time <300 seconds) 1 day after undergoing endovascular coil embolization of the aneurysm. Postoperatively, there were no extensions of the intracerebral and intracerebellar hematoma. After intensive rehabilitation therapy, the patient recovered fully except for residual bilateral claudication because of preoperative bilateral embolism to both superficial femoral arteries...
November 1, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/29093770/associates-and-prognosis-of-giant-left-atrium-single-center-experience
#6
Hyoeun Kim, Young-Ah Park, Sung Min Choi, Hyemoon Chung, Jong-Youn Kim, Pil-Ki Min, Young Won Yoon, Byoung Kwon Lee, Bum-Kee Hong, Se-Joong Rim, Hyuck Moon Kwon, Eui-Young Choi
Background: Left atrial (LA) remodeling develops as a result of longstanding pressure overload. However, determinants and clinical outcome of excessive remodeling, so called giant left atrium (GLA), are not clear. Methods: Clinical characteristics of patients with GLA (antero-posterior diameter higher than 65 mm), including echo-Doppler parameters, and follow-up clinical outcomes from a tertiary referral hospital were investigated. Results: Among 68519 consecutive primary patients who underwent echocardiography over a period of 10 years, data from 163 GLA cases (0...
September 2017: Journal of Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/29092010/transoesophageal-echo-guided-mitral-valve-repair-using-the-harpoon-system
#7
Gino Gerosa, Augusto D'Onofrio, Laura Besola, Andrea Colli
Transapical off-pump echo-guided mitral valve repair with implantation of artificial ePTFE chordae with the Harpoon device has been proposed to treat patients presenting with severe mitral regurgitation due to posterior leaflet prolapse. The device is inserted in the left ventricle and steered to the surface of the diseased portion of the leaflet. The Harpoon device is actuated, and the leaflet is perforated by a needle that consequently releases an ePTFE chord that is fixed on the atrial surface by a double-helix coiled knot...
October 30, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29081173/-analysis-on-clinical-characteristics-and-prognosis-of-patients-with-mitral-valve-prolapse
#8
Y Guo, S Y Wang, X J Duan, X Wu, X X Zheng, J Lu, X H Huang
Objective: To evaluate the clinical characteristics and prognosis of patients with mitral valve prolapse (MVP). Methods: We retrospectively analyzed the clinical characteristics and prognosis of 148 MVP patients who underwent mitral valve surgery in Fuwai hospital from January 2012 to December 2015.The patients were divided into mucoid degeneration group (52 cases) and without mucoid degeneration group(19 cases) according to pathological examination of leaflets and chordate. Results: The clinical symptoms of MVP patients included dyspnea (59...
October 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29074049/the-dynamic-cardiac-biosimulator-a-method-for-training-physicians-in-beating-heart-mitral-valve-repair-procedures
#9
Alberto M Leopaldi, Krzysztof Wrobel, Giovanni Speziali, Sjoerd van Tuijl, Agne Drasutiene, W Randolph Chitwood
OBJECTIVE: Previously, cardiac surgeons and cardiologists learned to operate new clinical devices for the first time in the operating room or catheterization laboratory. We describe a biosimulator that recapitulates normal heart valve physiology with associated real-time hemodynamic performance. METHODS: To highlight the advantages of this simulation platform, transventricular extruded polytetrafluoroethylene artificial chordae were attached to repair flail or prolapsing mitral valve leaflets...
September 18, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29067708/preliminary-study-of-the-application-of-transthoracic-echocardiography-guided-three-dimensional-printing-for-the-assessment-of-structural-heart-disease
#10
Yanbo Zhu, Jianshi Liu, Lianqun Wang, Xin Guan, Yongjuan Luo, Jie Geng, Qingguo Geng, Yunjia Lin, Lixia Zhang, Xixue Li, Yaping Lu
OBJECTIVE: To investigate the feasibility and diagnostic value of a preoperative transthoracic echocardiography-guided three-dimensional printed model (TTE-guided 3DPM) for the assessment of structural heart disease (SHD). METHODS: Fourty-four patients underwent cardiac surgery at Tianjin Chest Hospital. The patients were preoperatively assessed using TTE-guided 3DPM, which was compared to conventional three-dimensional transthoracic echocardiography (3DTTE) along with direct intraoperative findings, which were considered the "gold standard...
October 25, 2017: Echocardiography
https://www.readbyqxmd.com/read/29059484/imaging-characteristics-of-papillary-muscle-site-of-origin-of-ventricular-arrhythmias-in-patients-with-mitral-valve-prolapse
#11
Brian L Fulton, Jackson J Liang, Andres Enriquez, Fermin C Garcia, Gregory E Supple, Michael P Riley, Robert D Schaller, Sanjay Dixit, David J Callans, Francis E Marchlinski, Yuchi Han
BACKGROUND: Mitral valve prolapse has been associated with increased risk of ventricular arrhythmias. We aimed to examine whether certain cardiac imaging characteristics are associated with papillary muscle origin of ventricular arrhythmias in these patients. METHODS AND RESULTS: We screened electronic medical records of all patients documented to have mitral valve prolapse on either transthoracic echocardiogram (TTE) or cardiac magnetic resonance imaging (CMR) in our center, who also underwent an electrophysiologic study (EPS) between 2007 and 2016...
October 23, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29049793/triangular-resection-versus-neochordal-replacement-for-posterior-leaflet-prolapse-a-morphological-assessment
#12
Wenrui Ma, Jiafei Chen, Wei Zhang, Weihua Wu, Wei Ye, Wei Shi, Ye Kong
OBJECTIVES: To evaluate the morphological reconstruction as assessed by 3D transoesophageal echocardiography after triangular resection and neochordal replacement in the treatment of posterior leaflet prolapse. METHODS: We retrospectively selected 46 patients with isolated posterior leaflet prolapse who were undergoing mitral valve repair using triangular resection ( n  = 20) and neochordal replacement ( n  = 26) techniques. Sixty patients without valvular heart disease were also included as the control group...
August 14, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29046487/autograft-valve-sparing-root-replacement-for-late-ross-failure-during-quadruple-valve-surgery
#13
Andrew B Goldstone, Christopher W Jensen, Mary Sheridan Bilbao, Y Joseph Woo
Approximately 25% of patients require reoperation within 15 yrs of a Ross procedure. Increasing experience with valve-sparing root replacement (VSRR) has led some surgeons to spare the autograft valve. Here, we demonstrate that all valves can be surgically repaired or replaced safely during autograft VSRR. As more patients are considered for this operation, coexistent mitral, tricuspid, and pulmonic valve dysfunction should not preclude salvage of the autograft valve, nor should autograft leaflet prolapse.
October 17, 2017: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29040517/filamin-a-mitral-valve-disease-prolapse-dystrophy-or-dysplasia
#14
Gaetano Thiene, Cristina Basso
No abstract text is available yet for this article.
October 12, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29027267/percutaneous-repair-of-severe-mitral-valve-regurgitation-secondary-to-chordae-rupture-in-octogenarians-using-mitraclip
#15
Nicolas Geis, Philip Raake, Derliz Mereles, Emmanuel Chorianopoulos, Gabor Szabo, Hugo A Katus, Raffi Bekeredjian, Sven T Pleger
OBJECTIVES: The aim of this study was to assess feasibility and clinical effectiveness of the MitraClip device in octogenarians suffering from severe mitral valve regurgitation due to chordae rupture. BACKGROUND: The MitraClip procedure is a suitable technique in high-risk surgical patients to achieve safe and effective percutaneous repair of mitral valve regurgitation. Octogenarians show cumulative risk and social aspects hindering mitral valve surgery. No data exists regarding the use of the MitraClip device in high-risk octogenarians suffering from mitral valve chordae rupture...
October 12, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29020406/new-insights-into-mitral-valve-dystrophy-a-filamin-a-genotype-phenotype-and-outcome-study
#16
Thierry Le Tourneau, Solena Le Scouarnec, Caroline Cueff, Daniel Bernstein, Jan J J Aalberts, Simon Lecointe, Jean Mérot, Jonathan A Bernstein, Toon Oomen, Christian Dina, Matilde Karakachoff, Hubert Desal, Ousama Al Habash, Francesca N Delling, Romain Capoulade, Albert J H Suurmeijer, David Milan, Russell A Norris, Roger Markwald, Elena Aikawa, Susan A Slaugenhaupt, Xavier Jeunemaitre, Albert Hagège, Jean-Christian Roussel, Jean-Noël Trochu, Robert A Levine, Florence Kyndt, Vincent Probst, Hervé Le Marec, Jean-Jacques Schott
Aims: Filamin-A (FLNA) was identified as the first gene of non-syndromic mitral valve dystrophy (FLNA-MVD). We aimed to assess the phenotype of FLNA-MVD and its impact on prognosis. Methods and results: We investigated the disease in 246 subjects (72 mutated) from four FLNA-MVD families harbouring three different FLNA mutations. Phenotype was characterized by a comprehensive echocardiography focusing on mitral valve apparatus in comparison with control relatives...
September 6, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29020352/the-mida-mortality-risk-score-development-and-external-validation-of-a-prognostic-model-for-early-and-late-death-in-degenerative-mitral-regurgitation
#17
Francesco Grigioni, Marie-Annick Clavel, Jean-Louis Vanoverschelde, Christophe Tribouilloy, Rodolfo Pizarro, Marianne Huebner, Jean-Francois Avierinos, Andrea Barbieri, Rakesh Suri, Agnés Pasquet, Dan Rusinaru, Gaetano D Gargiulo, Pablo Oberti, Alexis Théron, Francesca Bursi, Hector Michelena, Siham Lazam, Catherine Szymanski, Vuyisile T Nkomo, Martin Schumacher, Letizia Bacchi-Reggiani, Maurice Enriquez-Sarano
Aims: In degenerative mitral regurgitation (DMR), lack of mortality scores predicting death favours misperception of individual patients' risk and inappropriate decision-making. Methods and results: The Mitral Regurgitation International Database (MIDA) registries include 3666 patients (age 66 ± 14 years; 70% males; follow-up 7.8 ± 5.0 years) with pure, isolated, DMR consecutively diagnosed by echocardiography at tertiary (European/North/South-American) centres...
August 13, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28994690/perioperative-management-of-a-patient-with-glanzmann-s-thrombasthenia-for-mitral-valve-repair-under-cardiopulmonary-bypass
#18
Parimala Prasanna Simha, Prasanna Simha Mohan Rao, Deepak Arakalgud, Rakesh Rajashekharappa, Manjunath Narasimhaih
A 30-year-old male patient presented with Glanzmann's thrombasthenia and mitral valve prolapse. He was in acute decompensated congestive heart failure due to severe mitral and tricuspid regurgitation. After his cardiac failure had been stabilized, the patient was subjected to mitral and tricuspid valve repair. His transfusion requirements were guided by thrombelastography and his bleeding disorder was managed by infusing single donor plasmapheresed platelet transfusions in the perioperative period. The patient underwent surgery uneventfully...
October 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28993406/heritability-of-mitral-regurgitation-observations-from-the-framingham-heart-study-and-swedish-population
#19
Francesca N Delling, Xinjun Li, Shuo Li, Qiong Yang, Vanessa Xanthakis, Andreas Martinsson, Pontus Andell, Birgitta T Lehman, Ewa W Osypiuk, Plamen Stantchev, Bengt Zöller, Emelia J Benjamin, Kristina Sundquist, Ramachandran S Vasan, J Gustav Smith
BACKGROUND: Familial aggregation has been described for primary mitral regurgitation (MR) caused by mitral valve prolapse. We hypothesized that heritability of MR exists across different MR subtypes including nonprimary MR. METHODS AND RESULTS: Study participants were FHS (Framingham Heart Study) Generation 3 (Gen 3) and Gen 2 cohort participants and all adult Swedish siblings born after 1932 identified in 1997 and followed through 2010. MR was defined as ≥ mild regurgitation on color Doppler in FHS and from International Classification of Diseases codes in Sweden...
October 2017: Circulation. Cardiovascular Genetics
https://www.readbyqxmd.com/read/28992972/atrioventricular-valve-regurgitation-in-patients-undergoing-total-cavopulmonary-connection-impact-of-valve-morphology-and-underlying-mechanisms-on-survival-and-reintervention
#20
Masamichi Ono, Julie Cleuziou, Jelena Pabst von Ohain, Elisabeth Beran, Melchior Burri, Martina Strbad, Alfred Hager, Jürgen Hörer, Christian Schreiber, Rüdiger Lange
OBJECTIVE: The study objective was to determine the mechanisms of atrioventricular valve regurgitation in single-ventricle physiology and their influence on outcomes after total cavopulmonary connection. METHODS: Among 460 patients who underwent a total cavopulmonary connection, 101 (22%) had atrioventricular valve surgery before or coincident with total cavopulmonary connection. RESULTS: Atrioventricular valve morphology showed 2 separated in 33 patients, mitral in 11 patients, tricuspid in 41 patients, and common in 16 patients...
September 15, 2017: Journal of Thoracic and Cardiovascular Surgery
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