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https://www.readbyqxmd.com/read/29782080/implanting-neochordae-for-the-repair-of-mitral-valve-prolapse-using-a-prosthetic-ring-with-chordal-sizing-system-a-modified-technique-for-myxomatous-leaflets
#1
Antonio Lio, Antonio Miceli, Matteo Ferrarini, Andrea Montisci, Mattia Glauber
The use of artificial polytetrafluoroethylene (PTFE) chordae has been widely adopted in the setting of mitral valve repair. In this tutorial, we present a modified technique for neochordae placement using a semi-rigid complete ring, with a chordal sizing system. This ring was introduced with the aim of standardizing neo-chordae implantation and we introduce a modification of the implantation technique in the presence of myxomatous leaflets.
May 8, 2018: Multimedia Manual of Cardiothoracic Surgery: MMCTS
https://www.readbyqxmd.com/read/29780944/central-retinal-artery-occlusion-secondary-to-barlow-s-disease
#2
Carl S Wilkins, Katherine McCabe, Avnish Deobhakta, James Chelnis
Purpose: To report a rare case of isolated, unilateral CRAO in a young patient with mitral valve prolapse secondary to Barlow's disease. Observations: A 29-year-old woman with history of premature ventricular contractions and cardiac ablation presented to the emergency room after sudden onset painless visual loss in her left eye (OS). Her vision was 20/20 in her right eye and hand motion in the left. Fundus exam demonstrated a central retinal artery occlusion (CRAO) OS...
June 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29762926/genetic-complexity-of-mitral-valve-prolapse-revealed-by-clinical-and-genetic-evaluation-of-a-large-family
#3
Gloria T Haskell, Brian C Jensen, Cecile Skrzynia, Thelsa Pulikkotil, Christian R Tilley, Yurong Lu, Daniel S Marchuk, Leigh Ann Samsa, Kirk C Wilhelmsen, Ethan Lange, Cam Patterson, James P Evans, Jonathan S Berg
BACKGROUND: A genetic component to familial mitral valve prolapse (MVP) has been proposed for decades. Despite this, very few genes have been linked to MVP. Herein is described a four-generation pedigree with numerous individuals affected with severe MVP, some at strikingly young ages. METHODS: A detailed clinical evaluation performed on all affected family members demonstrated a spectrum of MVP morphologies and associated phenotypes. RESULTS: Linkage analysis failed to identify strong candidate loci, but revealed significant regions, which were investigated further using whole-exome sequencing of one of the severely affected family members...
September 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29750930/a-simplified-technique-for-complex-mitral-valve-regurgitation-via-minimally-invasive-approach
#4
Giuseppe Speziale, Marco Moscarelli, Nicola Di Bari, Raffaele Bonifazi, Massimo Salardino, Teresa De Donatis, Giusepe Nasso
BACKGROUND: Complex mitral valve disease can require surgical repair techniques that are challenging in a minimally invasive context and may expose patients to prolonged cardiopulmonary bypass and cross clamp times. Here, we review our simplified stepwise operative approach for the treatment of complex bileaflet mitral disease, on early outcomes and mid-term follow-up. METHODS: One hundred and forty consecutive patients with bileaflet disease underwent video-assisted right minimally invasive mitral valve repair at our surgical center between 2008 and 2016...
May 8, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29738755/durability-at-19-years-of-quadrangular-resection-with-annular-plication-for-mitral-regurgitation
#5
Elisabetta Lapenna, Benedetto Del Forno, Ludovica Amore, Stefania Ruggeri, Giuseppe Iaci, Davide Schiavi, Igor Belluschi, Marta Bargagna, Ottavio Alfieri, Michele De Bonis
BACKGROUND: To report the long-term (19 years) clinical and echocardiographic results of the quadrangular resection with annular plication and annuloplasty. METHODS: A hundred forty-five consecutive patients (mean age 58±11.1years, LVEF 59±9.5%) with severe degenerative mitral regurgitation due to posterior leaflet prolapse/flail, underwent quadrangular resection of the posterior leaflet combined with ring (127 patients,87.5%) or pericardium (18 patients,12.5%) annuloplasty...
May 5, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29735373/natural-history-of-echocardiographic-abnormalities-in-mucopolysaccharidosis-iii
#6
Carolyn M Wilhelm, Kristen V Truxal, Kim L McBride, John P Kovalchin, Kevin M Flanigan
BACKGROUND: Mucopolysaccharidosis (MPS) type III, Sanfilippo Syndrome, is an autosomal recessive lysosomal storage disorder. MPS I and II patients often develop cardiac involvement leading to early mortality, however there are limited data in MPS III. The objective of this study is to describe cardiac abnormalities in a large group of MPS III patients followed in a longitudinal natural history study designed to determine outcome measures for gene transfer trials. METHODS: A single center study of MPS III patients who were enrolled in the Nationwide Children's Hospital natural history study in 2014...
April 27, 2018: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/29732567/catheter-ablation-of-papillary-muscle-arrhythmias-implications-of-mitral-valve-prolapse-and-systolic-dysfunction
#7
Adam Lee, Christian Hamilton Craig, Russell Denman, Haris M Haqqani
BACKGROUND: The left ventricular papillary muscles are important components of the mitral valve apparatus. Catheter ablation of ventricular arrhythmias from these sites is challenging. We aim to describe the association between LV papillary muscle ventricular arrhythmias (VAs) and mitral valve prolapse (MVP), and to determine the outcomes of ablation in these patients with a focus on those with MVP and cardiomyopathy. METHODS: 152 patients underwent 170 consecutive procedures for ablation of focal VAs...
May 6, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29729267/good-five-year-durability-of-transapical-beating-heart-off-pump-mitral-valve-repair-with-neochordae
#8
Philipp Kiefer, Sabine Meier, Thilo Noack, Michael Andrew Borger, Joerg Ender, Alexandro Hoyer, Friedrich Wilhelm Mohr, Joerg Seeburger
BACKGROUND: Transapical, beating heart, off-pump implantation of neochordae for repair of mitral valve (MV) prolapse is of increasing interest. The aim of this study was to evaluate long term results for MV repair using the NeoChord system. METHODS: Six patients underwent treatment for severe primary mitral regurgitation (MR) using the NeoChord DS1000 system as part of the initial device safety and feasibility Transapical Artificial Chordae Tendinae (TACT) trial at our institution...
May 2, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29728065/prevalence-and-characteristics-of-primary-left-sided-valve-disease-in-a-cohort-of-15-000-patients-undergoing-echocardiography-studies-in-a-tertiary-hospital-in-uganda
#9
Joselyn Rwebembera, William Manyilirah, Zhang Wan Zhu, Juliet Nabbaale, Judith Namuyonga, Isaac Ssinabulya, Sulaiman Lubega, Peter Lwabi, John Omagino, Emmy Okello
BACKGROUND: Although rheumatic heart disease remains the leading cause of valve heart disease (VHD) in developing countries, other forms of valve disease have been over shadowed and not regarded as a public health problem. However, several facts suggest that the role of non-rheumatic VHD as a significant cardiovascular disease should be reconsidered. We aimed to assess the prevalence and characteristics of different forms of primary left sided valve diseases from a series of 15,009 echocardiographic studies...
May 4, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29719059/mitral-valve-prolapse-causes-arrhythmias-from-the-papillary-muscles-a-stretch-of-the-truth-or-reality
#10
EDITORIAL
Steven M Markowitz
No abstract text is available yet for this article.
May 2, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29717556/heart-failure-and-sudden-cardiac-death-in-heritable-thoracic-aortic-disease-caused-by-pathogenic-variants-in-the-smad3-gene
#11
Julie De Backer, Alan C Braverman
BACKGROUND: Predominant cardiovascular manifestations in the spectrum of Heritable Thoracic Aortic Disease include by default aortic root aneurysms- and dissections, which may be associated with aortic valve disease. Mitral- and tricuspid valve prolapse are other commonly recognized features. Myocardial disease, characterized by heart failure and/or malignant arrhythmias has been reported in humans and in animal models harboring pathogenic variants in the Fibrillin1 gene. METHODS: Description of clinical history of three cases from one family in Ghent (Belgium) and one family in St...
May 1, 2018: Molecular Genetics & Genomic Medicine
https://www.readbyqxmd.com/read/29716704/clinical-microbiological-characterization-and-risk-factors-of-mortality-in-infective-endocarditis-from-a-tertiary-care-academic-hospital-in-southern-india
#12
Prasanna Subbaraju, Shipra Rai, Jwalit Morakhia, Geet Midha, Asha Kamath, Kavitha Saravu
AIMS: To dissect the clinical-microbiological profile of Infective endocarditis (IE) population and to determine the risk factors for IE related mortality. METHODS: A cohort study was conducted using relevant data from clinical records of patients (≥12years) with definite/possible IE from December 2007 to December 2013 and was analyzed using appropriate statistical tests. RESULTS: In the cohort of 139 IE patients, mean age was 47.9±15.8years, with male preponderance (68...
March 2018: Indian Heart Journal
https://www.readbyqxmd.com/read/29709354/simple-versus-complex-degenerative-mitral-valve-disease
#13
Hoda Javadikasgari, Tomislav Mihaljevic, Rakesh M Suri, Lars G Svensson, Jose L Navia, Robert Z Wang, Bassman Tappuni, Ashley M Lowry, Kenneth R McCurry, Eugene H Blackstone, Milind Y Desai, Stephanie L Mick, A Marc Gillinov
OBJECTIVES: At a center where surgeons favor mitral valve (MV) repair for all subsets of leaflet prolapse, we compared results of patients undergoing repair for simple versus complex degenerative MV disease. METHODS: From January 1985 to January 2016, 6153 patients underwent primary isolated MV repair for degenerative disease, 3101 patients underwent primary isolated MV repair for simple disease (posterior prolapse), and 3052 patients underwent primary isolated MV repair for complex disease (anterior or bileaflet prolapse), based on preoperative echocardiographic images...
April 4, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29696429/the-pulmonary-artery-in-pediatric-patients-with-marfan-syndrome-an-underestimated-aspect-of-the-disease
#14
Veronika C Stark, Michael Huemmer, Jakob Olfe, Goetz C Mueller, Rainer Kozlik-Feldmann, Thomas S Mir
Aortic root dilatation and its complications are known to be the most important and life limiting features in patients with Marfan syndrome (MFS). Since monitoring of patients, preventive medical and surgical treatments are available nowadays, other MFS pathologies are becoming more relevant for the outcome of the disease. Main pulmonary artery (MPA) dilatation is a cardiac finding, which has not been fully investigated in children. Due to the similarities in tissue composition of the aortic and pulmonary root, MPA dilatation may cause complications and require treatment...
April 25, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29694606/cardiovascular-abnormalities-in-patients-with-oral-cleft-a-clinical-electrocardiographic-echocardiographic-study
#15
Gisele C P Leite, Marcela A G Ururahy, João F Bezerra, Valéria M G D M Lima, Maria I F Costa, Sandra S C Freire, André D Luchessi, Jussara M C Maia, Maria E F Brito, Vera L Gil-da-Silva-Lopes, Adriana A Rezende
OBJECTIVES: The present study aims to describe the clinical, electrocardiographic, and echocardiographic cardiological findings in a group of patients with oral clefts. METHODS: This is a prospective cross-sectional study on 70 children (age range from 13 days to 19 years) with oral clefts who attended the multidisciplinary program of a university hospital from March 2013 to September 2014. The patients were evaluated by a pediatric cardiologist and underwent detailed anamnesis, physical examination, electrocardiogram, and echocardiogram...
2018: Clinics
https://www.readbyqxmd.com/read/29673010/the-nightmare-ecg-of-a-spontaneously-aborted-sudden-cardiac-death
#16
Giovanni Coluccia, Raffaele Punzi, Silvia Polini, Concetto La Rosa, Mariano Rillo
We present the case of a spontaneously aborted sudden cardiac death related to an high-rate ventricular tachycardia in an healthy man with bileaflet mitral valve prolapse. An effective treatment of the patient, with complete suppression of ventricular ectopic activity, was achieved only combining medical therapy, ICD and catheter ablation, thus overcoming the limitations of each approach.
April 19, 2018: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/29657253/minimally-invasive-mitral-valve-repair-through-right-minithoracotomy-11-year-single-institute-experience
#17
Taichi Sakaguchi, Toshinori Totsugawa, Masahiko Kuinose, Kentaro Tamura, Arudo Hiraoka, Genta Chikazawa, Hidenori Yoshitaka
BACKGROUND: Although minimally invasive mitral valve repair (MIMVR) is increasingly being performed, only a few clinical studies from Japanese institutions have been reported.Methods and Results:From 2006 to 2017, 387 consecutive patients (135 females, mean age 56±13 years) underwent an initial isolated MIMVR through a right minithoracotomy. The mitral etiology was degenerative in 348, functional in 22, and endocarditis in 13 cases. Repair techniques included leaflet resection/plication in 280, chordal reconstruction in 109, and annuloplasty alone in 24 patients, and concomitant procedures included tricuspid valve repair and atrial fibrillation ablation in 70 (18...
April 13, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29644231/mechanistic-insights-of-the-left-ventricle-structure-and-fibrosis-in-the-arrhythmogenic-mitral-valve-prolapse
#18
REVIEW
Leticia Fernández-Friera, Rafael Salguero, Luca Vannini, Ana Fidalgo Argüelles, Fernando Arribas, Jorge Solís
Mitral valve prolapse (MVP) is a common and benign condition. However, some anatomic forms have been recently associated with life-threatening ventricular arrhythmias and sudden cardiac death. Imaging MVP holds the promise of individualized MVP risk assessment. Noninvasive imaging techniques available today are playing an increasingly important role in the diagnosis, prognosis and monitoring of MVP. In this article, we will review the current evidence on arrhythmogenic MVP, with special focus on the utility of echocardiography and CMR for identifying benign and "malignant" forms of MVP...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29643879/transesophageal-echocardiography-in-cardiogenic-embolic-cerebral-infarction
#19
Wen Chu, Hua Wang
Objective: To evaluate the diagnostic values of transesophageal echocardiography (TEE) and transthoracic echocardiography (TTE) in cardiogenic embolic cerebral infarction. Methods: Fifty patients with occult cerebral infarction who were admitted to the hospital between June 2015 and June 2016 were selected as research subjects. The patients were diagnosed by transesophageal echocardiography and transthoracic echocardiography. Diagnostic data were compared to analyze the values of the two diagnostic methods...
January 2018: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29629022/impact-of-a-geometric-correction-for-proximal-flow-constraint-on-the-assessment-of-mitral-regurgitation-severity-using-the-proximal-flow-convergence-method
#20
Jeong Yoon Jang, Joon-Won Kang, Dong Hyun Yang, Sahmin Lee, Byung Joo Sun, Dae-Hee Kim, Jong-Min Song, Duk-Hyun Kang, Jae-Kwan Song
Background: Overestimation of the severity of mitral regurgitation (MR) by the proximal isovelocity surface area (PISA) method has been reported. We sought to test whether angle correction (AC) of the constrained flow field is helpful to eliminate overestimation in patients with eccentric MR. Methods: In a total of 33 patients with MR due to prolapse or flail mitral valve, both echocardiography and cardiac magnetic resonance image (CMR) were performed to calculate regurgitant volume (RV)...
March 2018: Journal of Cardiovascular Ultrasound
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