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https://www.readbyqxmd.com/read/28426305/us-public-opinion-on-carrying-firearms-in-public-places
#1
Julia A Wolfson, Stephen P Teret, Deborah Azrael, Matthew Miller
OBJECTIVES: To estimate US public opinion, overall and by gun ownership status, about the public places where legal gun owners should be allowed to carry firearms. METHODS: We fielded an online survey among 3949 adults, including an oversample of gun owners and veterans, in April 2015. We used cross-tabulations with survey weights to generate nationally representative estimates. RESULTS: Fewer than 1 in 3 US adults supported gun carrying in any of the specified venues...
April 20, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28394817/comparative-bone-regeneration-potential-studies-of-collagen-heparin-and-polydopamine-coated-multichannelled-bcp-granules
#2
Gun Hee Lee, Preeti Makkar, Kallyanshis Paul, Byong Taek Lee
The present work is a comparative assessment of the bone regeneration potentiality of bone substitutes comprised of bioactive polymer coated biphasic calcium phosphate (BCP) granules. The bone substitutes were primarily composed of multichanneled BCP granules which were coated separately with biochemical polymer coatings, namely collagen, heparin or polydopamine, using chemical methods. The morphological features and chemical structure of the granules and surface coatings were characterized by scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) respectively...
April 6, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28368954/u-s-army-physical-demands-study-reliability-of-simulations-of-physically-demanding-tasks-performed-by-combat-arms-soldiers
#3
Stephen A Foulis, Jan E Redmond, Peter N Frykman, Maj Bradley J Warr, Edward J Zambraski, Marilyn A Sharp
Recently, the US Army has mandated that Soldiers must successfully complete the physically demanding tasks of their job in order to graduate from their Initial Military Training. Evaluating individual Soldiers in the field is difficult; however, simulations of these tasks may aid in the assessment of Soldiers' abilities. The purpose of this study was to determine the reliability of simulated physical Soldiering tasks relevant to Combat Arms Soldiers. Three cohorts of ∼50 Soldiers repeated a subset of eight simulated tasks four times over two weeks...
March 31, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28367592/whose-guns-are-stolen-the-epidemiology-of-gun-theft-victims
#4
David Hemenway, Deborah Azrael, Matthew Miller
BACKGROUND: Gun theft is an important source of guns used by criminals. Yet no empirical work has focused on the characteristics of gun owners that distinguish those who have had their guns stolen from those who have not. In this study, we examine the demographics and behavioral characteristics of gun owners who report having had a gun stolen. METHODS: Data come from a nationally representative probability-based online survey conducted in April 2015, with a linked follow-up survey in November 2015 that asked gun owners about any theft of their guns in the past 5 years...
December 2017: Injury Epidemiology
https://www.readbyqxmd.com/read/28260243/aggressive-and-violent-behavior-and-emotional-self-efficacy-is-there-a-relationship-for-adolescents
#5
Robert F Valois, Keith J Zullig, Asa A Revels
BACKGROUND: In this cross-sectional study we explored relationships between aggressive and violent behaviors and emotional self-efficacy (ESE) in a statewide sample of public high school adolescents in South Carolina (N = 3836). METHODS: The US Centers for Disease Control and Prevention Youth Risk Behavior Survey items on aggressive and violent behavior items and an adolescent ESE scale were used. Logistic regression analyses and multivariate models constructed separately, revealed significant race by sex findings...
April 2017: Journal of School Health
https://www.readbyqxmd.com/read/28260239/ten-year-secular-trends-in-youth-violence-results-from-the-philadelphia-youth-risk-behavior-survey-2003-2013
#6
Andrew C Pool, Freda Patterson, Ingrid Y Luna, Bernadette Hohl, Katherine W Bauer
BACKGROUND: Youth violence reduction is a public health priority, yet few studies have examined secular trends in violence among urban youth, who may be particularly vulnerable to numerous forms of violence. This study examines 10-year secular trends in the prevalence of violence-related behaviors among Philadelphia high school students. METHODS: Repeated cross-sectional data were analyzed from 5 waves of the Philadelphia Youth Risk Behavior Survey (YRBS) from 2003 to 2013...
April 2017: Journal of School Health
https://www.readbyqxmd.com/read/28207333/handgun-legislation-and-changes-in-statewide-overall-suicide-rates
#7
Michael D Anestis, Joye C Anestis, Sarah E Butterworth
OBJECTIVES: To examine the extent to which 4 laws regulating handgun ownership were associated with statewide suicide rate changes. METHODS: To test between-group differences in statewide suicide rate changes between 2013 and 2014 in all 50 states and the District of Columbia with and without specific laws, we ran analyses of covariance. RESULTS: We found significant differences in suicide rate changes from 2013 to 2014 in states with mandatory waiting periods and universal background checks relative to states without such laws...
April 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28193713/firearm-carrying-and-concurrent-substance-use-behaviours-in-a-community-based-sample-of-emerging-adults
#8
Robert N Buschmann, John D Prochaska, Jacques G Baillargeon, Jeff R Temple
INTRODUCTION: This paper examines associations between high-risk gun carrying and substance use in emerging adults (ages 18-22). The coexistence of these high-risk behaviours in a general population of emerging adults can have disastrous consequences. METHODS: Dating it Safe is an ongoing longitudinal (2010-2016) survey of emerging adults recruited from seven high schools in five south-east Texas-area school districts (current sample n=684). Multiple logistic regression modelling was used to examine the association between past-year use of legal and illegal substances and past-year firearm carrying for a reason other than sport or hunting...
February 13, 2017: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
https://www.readbyqxmd.com/read/28135726/the-relationships-among-exposure-to-violence-psychological-distress-and-gun-carrying-among-male-adolescents-found-guilty-of-serious-legal-offenses-a-longitudinal-cohort-study
#9
Joan A Reid, Tara N Richards, Thomas A Loughran, Edward P Mulvey
Background: Gun violence and psychological problems are often conflated in public discourse on gun safety. However, few studies have empirically assessed the effect of exposure to violence when exploring the association between gun carrying and psychological distress. Objective: To examine the potential effect of exposure to violence on the associations between gun carrying and psychological distress among vulnerable adolescents. Design: Longitudinal cohort study...
March 21, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28134622/mutations-in-tropomyosin-4-underlie-a-rare-form-of-human-macrothrombocytopenia
#10
Irina Pleines, Joanne Woods, Stephane Chappaz, Verity Kew, Nicola Foad, José Ballester-Beltrán, Katja Aurbach, Chiara Lincetto, Rachael M Lane, Galina Schevzov, Warren S Alexander, Douglas J Hilton, William J Astle, Kate Downes, Paquita Nurden, Sarah K Westbury, Andrew D Mumford, Samya G Obaji, Peter W Collins, Fabien Delerue, Lars M Ittner, Nicole S Bryce, Mira Holliday, Christine A Lucas, Edna C Hardeman, Willem H Ouwehand, Peter W Gunning, Ernest Turro, Marloes R Tijssen, Benjamin T Kile
Platelets are anuclear cells that are essential for blood clotting. They are produced by large polyploid precursor cells called megakaryocytes. Previous genome-wide association studies in nearly 70,000 individuals indicated that single nucleotide variants (SNVs) in the gene encoding the actin cytoskeletal regulator tropomyosin 4 (TPM4) exert an effect on the count and volume of platelets. Platelet number and volume are independent risk factors for heart attack and stroke. Here, we have identified 2 unrelated families in the BRIDGE Bleeding and Platelet Disorders (BPD) collection who carry a TPM4 variant that causes truncation of the TPM4 protein and segregates with macrothrombocytopenia, a disorder characterized by low platelet count...
March 1, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28073074/tribocorrosion-behavior-of-bio-functionalized-highly-porous-titanium
#11
F Toptan, A C Alves, A M P Pinto, P Ponthiaux
Titanium and its alloys are widely used in orthopedic and dental implants, however, some major clinical concerns such as poor wear resistance, lack of bioactivity, and bone resorption due to stress shielding are yet to be overcome. In order to improve these drawbacks, highly porous Ti samples having functionalized surfaces were developed by powder metallurgy with space holder technique followed by anodic treatment. Tribocorrosion tests were performed in 9g/L NaCl solution using a unidirectional pin-on-disc tribometer under 3N normal load, 1Hz frequency and 4mm track diameter...
January 4, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28069415/silymarin-exerts-antifungal-effects-via-membrane-targeted-mode-of-action-by-increasing-permeability-and-inducing-oxidative-stress
#12
Dae Gyu Yun, Dong Gun Lee
Silymarin, which is derived from the seeds of Silybum marianum, has been widely used to prevent and treat liver disorders. It is also consumed as a dietary supplement to improve liver function, as it does not exhibit any toxic effects in humans. Recently, silymarin has been reported to show antimicrobial effects against various pathogenic microorganisms, but the mode of action remains unknown. Thus, we investigated the antifungal activity of silymarin and aimed to determine the underlying mechanism. Initially, a propidium iodide assay was carried out; the results indicated that silymarin induced injury to the fungal plasma membrane...
January 7, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28064138/ultrasensitive-photoacoustic-sensor-based-on-quantum-cascade-laser-spectroscopy
#13
Deepak Kumar, Surya Gautam, Subodh Kumar, Saurabh Gupta, Hari B Srivastava, Surya N Thakur, Ramesh C Sharma
The paper focuses on development of ultra-sonic detection system based on laser photoacoustic spectroscopic technique and processing of signal for detection of very low quantity chemicals, explosive materials, and mixtures of these hazardous molecules. The detection system has been developed for the first time with specially designed one side open photo-acoustic cell having high quality factor. Explosive and Hazardous materials like RDX, DNT, PETN, Gun Powder, TATP (Tri acetone tri-peroxide) and their simulants like Acetone were detected in 7 to 9μm wavelength band...
November 23, 2016: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28058592/parallel-spectral-acquisition-with-orthogonal-icr-cells
#14
Sung-Gun Park, Gordon A Anderson, James E Bruce
FT-based high performance mass analyzers yield increased resolving power and mass measurement accuracy, yet require increased duration of signal acquisition that can limit many applications. The implementation of stronger magnetic fields, multiple detection electrodes for harmonic signal detection, and an array of multiple mass analyzers arranged along the magnetic field axis have been used to decrease required acquisition time. The results presented here show that multiple ion cyclotron resonance (ICR) mass analyzers can also be implemented orthogonal to the central magnetic field axis...
March 2017: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/28040564/role-of-potassium-channels-in-chlorogenic-acid-induced-apoptotic-volume-decrease-and-cell-cycle-arrest-in-candida-albicans
#15
JiEun Yun, Dong Gun Lee
BACKGROUND: Chlorogenic acid (CRA) is an abundant phenolic compound in the human diet. CRA has a potent antifungal effect, inducing cell death in Candida albicans. However, there are no further studies to investigate the antifungal mechanism of CRA, associated with ion channels. METHODS: To evaluate the inhibitory effects on CRA-induced cell death, C. albicans cells were pretreated with potassium and chloride channel blockers, separately. Flow cytometry was carried out to detect several hallmarks of apoptosis, such as cell cycle arrest, caspase activation, and DNA fragmentation, after staining of the cells with SYTOX green, FITC-VAD-FMK, and TUNEL...
March 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27955825/possession-of-weapon-and-school-violence-among-adolescents-and-their-association-with-history-of-traumatic-brain-injury-substance-use-and-mental-health-issues
#16
Gabriela Ilie, Robert E Mann, Angela Boak, Hayley A Hamilton, Jürgen Rehm, Michael D Cusimano
PURPOSE: Assessment of the association between illegal possession of weapon and assault on school property among adolescents with and without a history of traumatic brain injury (TBI) while assessing risk factors for these outcomes. METHODS: Data were derived from the Centre for Addiction and Mental Health's 2013 Ontario Student Drug Use and Health Survey completed by students in grades 7-12 (ages 11-20). RESULTS: In this sample of 5478 adolescents, 6...
February 2017: Injury
https://www.readbyqxmd.com/read/27873295/colleges-and-universities-sticking-to-their-guns
#17
Jesse Perez Mendez, Lou Sabina, Jon Loffi
Firearm possession on college and university campuses remains a volatile public policy issue among policymakers, legislators, scholars, and administrators. Given the American federal governmental structure, many states have developed legislative approaches to "carry on campus" policies throughout the years that align with federal law. This study explores the diversity of state approaches and nuances of "carry on campus" throughout recent years and current state legislation under consideration. The implications of "carry on campus" legislation vary on college campuses, depending on applicable state law; however, some general dynamics apply to all...
September 2016: Journal of Emergency Management: JEM
https://www.readbyqxmd.com/read/27865616/phenylpropanoids-from-cinnamon-bark-reduced-%C3%AE-amyloid-production-by-the-inhibition-of-%C3%AE-secretase-in-chinese-hamster-ovarian-cells-stably-expressing-amyloid-precursor-protein
#18
Yu Jeong Kang, Dae-Gun Seo, So-Young Park
β-Amyloid (Aβ) is a substance of Alzheimer disease (AD), which is generated via the amyloidogenic pathway from amyloid precursor protein (APP) by β-secretase and γ-secretase. Inhibition of Aβ production is a potential therapeutic approach to AD. Thus, we tested the hypothesis that cinnamon bark (Cinnamomi Cortex Spissus), the dried bark of Cinnamomum cassia Blume (Lauraceae), and its constituents are beneficial to AD. The methanol extract of cinnamon bark efficiently reduced Aβ40 production in Chinese hamster ovarian (CHO) cells stably expressing APP as determined by enzyme-linked immunosorbent assay...
November 2016: Nutrition Research
https://www.readbyqxmd.com/read/27793475/biochemical-analysis-of-recombinant-cyp4a11-allelic-variant-enzymes-w126r-k276t-and-s353g
#19
Songhee Han, Gun-Su Cha, Young-Jin Chun, Chang Hoon Lee, Donghak Kim, Chul-Ho Yun
Human CYP4A11 is the major ω-hydroxylase of fatty acids in the liver and kidneys. It produces 20-hydroxyeicosatetraenoic acid as well as hydroxylates fatty acids. In this study, we investigated the biochemical properties of three alleles of CYP4A11: W126R, K276T, and S353G. Site-directed mutagenesis of the wild type CYP4A11 was performed, to construct the W126R, K276T, and S353G variant clones. The CYP4A11 wild type and variant constructs were heterologously expressed in Escherichia coli. CO-binding spectra showed the expression of the wild type, K276T and S353G variants, indicating the functional P450 holoenzyme...
December 2016: Drug Metabolism and Pharmacokinetics
https://www.readbyqxmd.com/read/27622112/pediatric-arm-reconstruction-after-shot-gun-injury-using-peroneal-free-flap-and-pedicled-latissimus-dorsi-muscle-flap-late-follow-up
#20
Carlos Olvera-Caballero, Abel Ortiz-Dominguez
A 15-year-old patient harmed himself upon firing a shotgun that he was carrying when he slipped and fell, causing a destructive wound in the right arm with a medial entry hole and a posterolateral exit hole. The biceps, coracobrachialis, triceps, deltoids, skin cover, and humerus were injured; however, the blood vessels and major nerves of the area were surprisingly not affected. The residual skin muscle defect after debridements was 16 × 5 cm medially and posteriorly, and the bone loss was 7 cm. The wound was reconstructed during a single surgery with a free fibula flap and a pedicled flap of latissimus dorsi...
August 2016: Plastic and Reconstructive Surgery. Global Open
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