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https://www.readbyqxmd.com/read/27873295/colleges-and-universities-sticking-to-their-guns
#1
Jesse Perez Mendez, Lou Sabina, Jon Loffi
Firearm possession on college and university campuses remains a volatile public policy issue among policymakers, legislators, scholars, and administrators. Given the American federal governmental structure, many states have developed legislative approaches to "carry on campus" policies throughout the years that align with federal law. This study explores the diversity of state approaches and nuances of "carry on campus" throughout recent years and current state legislation under consideration. The implications of "carry on campus" legislation vary on college campuses, depending on applicable state law; however, some general dynamics apply to all...
September 2016: Journal of Emergency Management: JEM
https://www.readbyqxmd.com/read/27865616/phenylpropanoids-from-cinnamon-bark-reduced-%C3%AE-amyloid-production-by-the-inhibition-of-%C3%AE-secretase-in-chinese-hamster-ovarian-cells-stably-expressing-amyloid-precursor-protein
#2
Yu Jeong Kang, Dae-Gun Seo, So-Young Park
β-Amyloid (Aβ) is a substance of Alzheimer disease (AD), which is generated via the amyloidogenic pathway from amyloid precursor protein (APP) by β-secretase and γ-secretase. Inhibition of Aβ production is a potential therapeutic approach to AD. Thus, we tested the hypothesis that cinnamon bark (Cinnamomi Cortex Spissus), the dried bark of Cinnamomum cassia Blume (Lauraceae), and its constituents are beneficial to AD. The methanol extract of cinnamon bark efficiently reduced Aβ40 production in Chinese hamster ovarian (CHO) cells stably expressing APP as determined by enzyme-linked immunosorbent assay...
October 15, 2016: Nutrition Research
https://www.readbyqxmd.com/read/27793475/biochemical-analysis-of-recombinant-cyp4a11-allelic-variant-enzymes-w126r-k276t-and-s353g
#3
Songhee Han, Gun-Su Cha, Young-Jin Chun, Chang Hoon Lee, Donghak Kim, Chul-Ho Yun
Human CYP4A11 is the major ω-hydroxylase of fatty acids in the liver and kidneys. It produces 20-hydroxyeicosatetraenoic acid as well as hydroxylates fatty acids. In this study, we investigated the biochemical properties of three alleles of CYP4A11: W126R, K276T, and S353G. Site-directed mutagenesis of the wild type CYP4A11 was performed, to construct the W126R, K276T, and S353G variant clones. The CYP4A11 wild type and variant constructs were heterologously expressed in Escherichia coli. CO-binding spectra showed the expression of the wild type, K276T and S353G variants, indicating the functional P450 holoenzyme...
September 19, 2016: Drug Metabolism and Pharmacokinetics
https://www.readbyqxmd.com/read/27622112/pediatric-arm-reconstruction-after-shot-gun-injury-using-peroneal-free-flap-and-pedicled-latissimus-dorsi-muscle-flap-late-follow-up
#4
Carlos Olvera-Caballero, Abel Ortiz-Dominguez
A 15-year-old patient harmed himself upon firing a shotgun that he was carrying when he slipped and fell, causing a destructive wound in the right arm with a medial entry hole and a posterolateral exit hole. The biceps, coracobrachialis, triceps, deltoids, skin cover, and humerus were injured; however, the blood vessels and major nerves of the area were surprisingly not affected. The residual skin muscle defect after debridements was 16 × 5 cm medially and posteriorly, and the bone loss was 7 cm. The wound was reconstructed during a single surgery with a free fibula flap and a pedicled flap of latissimus dorsi...
August 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27601685/abatement-of-particulate-matter-emission-from-experimental-aviary-housings-for-laying-hens-by-spraying-rapeseed-oil
#5
A Winkel, J W van Riel, R A van Emous, A J A Aarnink, P W G Groot Koerkamp, N W M Ogink
In alternative systems for laying hens, concentrations and emission rates of particulate matter (PM) give reason for concern with regard to working conditions, bird health and productivity, and health of residents living near farms. Previously, we found that spraying a film of rapeseed oil onto the litter of broilers could substantially reduce PM concentrations and emissions. The objective of this study was to establish dose-response effects of oil spraying in aviaries on concentrations and emission rates of PM with aerodynamic diameters less than 10 μm (PM10) and 2...
December 1, 2016: Poultry Science
https://www.readbyqxmd.com/read/27417128/insulin-pump-therapy-in-children-with-type-1-diabetes-analysis-of-data-from-the-sweet-registry
#6
Agnieszka Szypowska, Anke Schwandt, Jannet Svensson, Shlomit Shalitin, Roque Cardona-Hernandez, Gun Forsander, Frida Sundberg, Carine De Beaufort, David Maahs, Claudio Maffeis, Stephen M P O'Riordan, Iveta Dzivite Krisane, Mauro Scharf, Sofia Castro, Maia Konstantinova, Barbora Obermannova, Kristina Casteels, Damla Gökşen, Júlia Galhardo, Christina Kanaka-Gantenbein, Birgit Rami-Merhar, Laszlo Madacsy
BACKGROUND: Intensified insulin delivery using multiple daily injections (MDI) or continuous subcutaneous insulin infusion (CSII) is recommended in children with type 1 diabetes (T1D) to achieve good metabolic control. OBJECTIVE: To examine the frequency of pump usage in T1D children treated in SWEET (Better control in Paediatric and Adolescent diabeteS: Working to crEate CEnTers of Reference) centers and to compare metabolic control between patients treated with CSII vs MDI...
October 2016: Pediatric Diabetes
https://www.readbyqxmd.com/read/27413324/oral-azithromycin-versus-its-combination-with-miltefosine-for-the-treatment-of-experimental-old-world-cutaneous-leishmaniasis
#7
Eglal I Amer, Maha M Eissa, Shereen F Mossallam
Leishmaniasis is one of the neglected infectious diseases included in the World Health Organization's list of the top guns of antimicrobial resistance. Miltefosine is the first and the only available oral effective therapy for leishmaniasis. For fear of its potential resistance, identification of alternative, effective and safe drugs is urgently needed. Therefore, in view of azithromycin promising activity against a number of Leishmania species, this work was carried out to evaluate the efficacy of oral azithromycin alone versus its combination with miltefosine against experimental Old World Cutaneous leishmaniasis thus, can provide another alternative oral therapy or for the first time an oral combination therapy for leishmaniasis...
June 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27411912/abducens-nerve-palsy-as-a-postoperative-complication-of-minimally-invasive-thoracic-spine-surgery-a-case-report
#8
Luiz Henrique Dias Sandon, Gun Choi, EunSoo Park, Hyung-Chang Lee
BACKGROUND: Thoracic disc surgeries make up only a small number of all spine surgeries performed, but they can have a considerable number of postoperative complications. Numerous approaches have been developed and studied in an attempt to reduce the morbidity associated with the procedure; however, we still encounter cases that develop serious and unexpected outcomes. CASE PRESENTATION: This case report presents a patient with abducens nerve palsy after minimally invasive surgery for thoracic disc herniation with an intraoperative spinal fluid fistula...
July 13, 2016: BMC Surgery
https://www.readbyqxmd.com/read/27356412/-development-and-application-of-jingcen-dy-1-spraying-tanker-for-oncomelania-hupensis-snail-control
#9
Jia-song Wang, Liang-cai He, Xian-bing Rong, Mei-zhi Yuan, Min Wang, Ke-jun Wang, Ya-dong Zhou, Ke- qing Tian, Xiao-feng Zhang
OBJECTIVE: To develop a Jingcen DY-1 type spraying tanker for Oncomelania hupensis snail control and evaluate its effect of field application as well as the cost. METHODS: The currently available tractor was used as a vector, and the mechanical and electrical equipments and containers were integrated with shafts, pipelines and electric lines to produce a spraying tanker for snail control, with the functions of carrying people and molluscicides, generating electric power and getting water, mixing stocking solutions, adjusting molluscicide solutions evenly, and spraying drugs...
February 2016: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/27353507/security-personnel-practices-and-policies-in-u-s-hospitals-findings-from-a-national-survey
#10
Ashley L Schoenfisch, Lisa A Pompeii
Concerns of violence in hospitals warrant examination of current hospital security practices. Cross-sectional survey data were collected from members of a health care security and safety association to examine the type of personnel serving as security in hospitals, their policies and practices related to training and weapon/restraint tool carrying/use, and the broader context in which security personnel work to maintain staff and patient safety, with an emphasis on workplace violence prevention and mitigation...
June 27, 2016: Workplace Health & Safety
https://www.readbyqxmd.com/read/27245809/characteristics-of-youth-with-combined-histories-of-violent-behavior-suicidal-ideation-or-behavior-and-gun-carrying
#11
Joseph E Logan, Kevin J Vagi, Deborah Gorman-Smith
BACKGROUND: Youth reporting combined histories of nonfatal violence, suicidal ideation/behavior, and gun-carrying (VSG) are at risk for perpetrating fatal interpersonal violence and self-harm. AIMS: We characterized these youth to inform prevention efforts. METHOD: We analyzed 2004 data from 3,931 seventh-, ninth-, and 11-12th-grade youth and compared VSG youth (n = 66) with non-gun carrying youth who either had no histories of violence or suicidal thoughts/behavior (n = 1,839), histories of violence (n = 884), histories of suicidal thoughts/behaviors (n = 552), or both (n = 590)...
June 1, 2016: Crisis
https://www.readbyqxmd.com/read/27192640/combined-external-endoscopic-endonasal-assisted-removal-of-a-nail-gun
#12
Puya Dehgani Mobaraki, Fabrizio Longari, Ruggero Lapenna, Giampietro Ricci
Management of penetrating trauma to the paranasal sinuses with retained foreign bodies represents a challenge due to the proximity to vital neurovascular structures. The authors report the successful treatment of a patient with a work-related nail gun injury, carried out by means of a combined endoscopic endonasal external assisted procedure.A transnasal endoscopic approach was planned to minimize inadvertent movements of the nail during surgery and in case necessary to repair the orbit or skull base. No major bleeding or neurovascular complication was observed after surgery and a computed tomography scan was performed after surgery confirming the complete removal of the nail and with no damage of the orbit nor the skull base...
June 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27176665/adolescent-gun-violence-prevention-what-we-know-and-what-we-can-do-to-keep-young-people-safe
#13
Nancy A Dodson
PURPOSE OF REVIEW: This review will focus on recent research, initiatives, and legislation regarding the issue of gun violence as it pertains to adolescents. RECENT FINDINGS: Homicide and suicide continue to be major killers of adolescents in the United States. Gun homicide kills teens in the most urban areas of the United States at the same rate as suicide kills teens in the most rural areas of the United States. Research on assault-injured youth sheds light on risk factors for teen gun homicide, and has found high rates of illegal gun carrying and retaliatory attitudes among at-risk teens...
August 2016: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/27170390/pathogenesis-diagnosis-and-treatment-of-hemochromatosis
#14
Heinz Zoller, Benjamin Henninger
Hemochromatosis is a common cause of chronic liver disease and HFE genotyping allows decisive and non-invasive diagnosis. Molecular and clinical genetic studies have led to the identification of genes other than HFE in patients with inherited diseases associated with increased hepatic iron storage that can cause hemochromatosis, which adds complexity to a diagnostic approach to patients with suspected hemochromatosis. Despite major advances in genetics, hepatic iron quantification by non-invasive methods therefore remains the key to the diagnosis of hemochromatosis...
2016: Digestive Diseases
https://www.readbyqxmd.com/read/26990869/further-evidence-of-increasing-diversity-of-plasmodium-vivax-in-the-republic-of-korea-in-recent-years
#15
Jung-Yeon Kim, Youn-Kyoung Goo, Young-Gun Zo, So-Young Ji, Hidayat Trimarsanto, Sheren To, Taane G Clark, Ric N Price, Sarah Auburn
BACKGROUND: Vivax malaria was successfully eliminated from the Republic of Korea (ROK) in the late 1970s but re-emerged in 1993. Two decades later as the ROK enters the final stages of malaria elimination, dedicated surveillance of the local P. vivax population is critical. We apply a population genetic approach to gauge P. vivax transmission dynamics in the ROK between 2010 and 2012. METHODOLOGY/PRINCIPAL FINDINGS: P. vivax positive blood samples from 98 autochthonous cases were collected from patients attending health centers in the ROK in 2010 (n = 27), 2011 (n = 48) and 2012 (n = 23)...
2016: PloS One
https://www.readbyqxmd.com/read/26931958/injection-of-auxiliary-electrons-for-increasing-the-plasma-density-in-highly-charged-and-high-intensity-ion-sources
#16
F Odorici, L Malferrari, A Montanari, R Rizzoli, D Mascali, G Castro, L Celona, S Gammino, L Neri
Different electron guns based on cold- or hot-cathode technologies have been developed since 2009 at INFN for operating within ECR plasma chambers as sources of auxiliary electrons, with the aim of boosting the source performances by means of a higher plasma lifetime and density. Their application to microwave discharge ion sources, where plasma is not confined, has required an improvement of the gun design, in order to "screen" the cathode from the plasma particles. Experimental tests carried out on a plasma reactor show a boost of the plasma density, ranging from 10% to 90% when the electron guns are used, as explained by plasma diffusion models...
February 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/26931850/a-compact-lithium-pellet-injector-for-tokamak-pedestal-studies-in-asdex-upgrade
#17
R Arredondo Parra, R Moreno Quicios, B Ploeckl, G Birkenmeier, A Herrmann, G Kocsis, F M Laggner, P T Lang, T Lunt, R Macian-Juan, V Rohde, G Sellmair, T Szepesi, E Wolfrum, W Zeidner, R Neu
Experiments have been performed at ASDEX Upgrade, aiming to investigate the impact of lithium in an all-metal-wall tokamak and attempting to enhance the pedestal operational space. For this purpose, a lithium pellet injector has been developed, capable of injecting pellets carrying a particle content ranging from 1.82 × 10(19) atoms (0.21 mg) to 1.64 × 10(20) atoms (1.89 mg). The maximum repetition rate is about 2 Hz. Free flight launch from the torus outboard side without a guiding tube was realized. In such a configuration, angular dispersion and speed scatter are low, and a transfer efficiency exceeding 90% was achieved in the test bed...
February 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/26917568/firearm-violence-and-effects-on-concealed-gun-carrying-large-debate-and-small-effects
#18
Jeremy G Carter, Michael Binder
Research has yet to identify a predictive relationship between crime and the issuance of aggregated concealed gun permits. The present study examines if a macro-level relationship exists between both concealed carry firearm applications and permits and violent crime committed with a firearm. Florida county-level data for concealed carry applications and violent crime are combined with police employment, socioeconomic, political, and firearm subculture variables across two temporal periods using both county and year fixed effects models...
February 24, 2016: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/26875099/relative-sensitivity-of-immunohistochemistry-multiple-reaction-monitoring-mass-spectrometry-in-situ-hybridization-and-pcr-to-detect-coxsackievirus-b1-in-a549-cells
#19
Jutta E Laiho, Maarit Oikarinen, Sarah J Richardson, Gun Frisk, Julius Nyalwidhe, Tanya C Burch, Margaret A Morris, Sami Oikarinen, Alberto Pugliese, Francesco Dotta, Martha Campbell-Thompson, Jerry Nadler, Noel G Morgan, Heikki Hyöty
BACKGROUND: Enteroviruses (EVs) have been linked to the pathogenesis of several diseases and there is a collective need to develop improved methods for the detection of these viruses in tissue samples. OBJECTIVES: This study evaluates the relative sensitivity of immunohistochemistry (IHC), proteomics, in situ hybridization (ISH) and RT-PCR to detect one common EV, Coxsackievirus B1 (CVB1), in acutely infected human A549 cells in vitro. STUDY DESIGN: A549 cells were infected with CVB1 and diluted with uninfected A549 cells to produce a limited dilution series in which the proportion of infected cells ranged from 10(-1) to 10(-8)...
April 2016: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/26827708/mucilaginibacter-carri-sp-nov-isolated-from-a-car-air-conditioning-system
#20
Dong-Uk Kim, Hyosun Lee, Hyun Kim, Song-Gun Kim, So Yoon Park, Jong-Ok Ka
A Gram-stain-negative, pink bacterial strain, designated PR0008KT, was isolated from an automobile evaporator core in Korea. The cells were obligately aerobic and rod-shaped. The strain grew at 10-40 °C (optimum, 20 °C), at pH 5-8 (optimum, 7), and in the presence of 0-1.5% (w/v) NaCl. Phylogenetically, the strain was closely related to members of the genus Mucilaginibacter (93.4-97.0% 16S rRNA sequence similarities) and showed a high sequence similarity with Mucilaginibacter litoreus BR-18T, Mucilaginibacter lutimaris BR-3T and Mucilaginibacter soli R9-65T (97...
April 2016: International Journal of Systematic and Evolutionary Microbiology
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