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Negative pressure therapy

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https://www.readbyqxmd.com/read/28526905/effectiveness-of-acellular-dermal-matrix-on-autologous-split-thickness-skin-graft-in-treatment-of-deep-tissue-defect-esthetic-subjective-and-objective-evaluation
#1
Yoo Jung Lee, Myong Chul Park, Dong Ha Park, Hyung Min Hahn, Sue Min Kim, Il Jae Lee
BACKGROUND: A split-thickness skin graft (STSG) is performed to cover a large full-thickness skin defect. Esthetic and functional deficits can result, and many studies have sought to overcome them. This study compared the effectiveness of the acellular dermal matrix (ADM) graft and STSG concerning esthetic and functional effectiveness of ADM on scar quality. METHODS: Of the patients who underwent anterolateral thigh free flap from 2011 to 2015, patients who received skin graft only (n = 10) or skin graft with ADM (n = 20) for coverage of the donor site were enrolled...
May 19, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28526612/histomorphological-observation-of-surgical-debridement-combined-with-negative-pressure-therapy-in-treatment-of-diabetic-foot
#2
Jiao-Yun Dong, Fei Song, Chun Qing, Shu-Liang Lu
PURPOSE: To further study the mechanism of epithelization on the fascia side of the flap after surgical incision and the treatment of the negative pressure therapy. METHODS: With the patients' informed consent, parts of tissue samples were obtained from a 51-year-old diabetic patient who was suffering lower extremity ulcers. The samples were processed with hematoxylin and eosin (HE) staining and Masson trichrome staining. The keratin 19, keratin 15 and carcino-embryonic antigen (CEA) were immunohistochemically detected...
April 20, 2017: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/28523167/a-novel-facilitated-negative-pressure-wound-therapy-for-thoracic-incision-infection-after-esophagectomy
#3
Zhi-Tian Wang, Jin-Lin Cao, Ping Yuan, Lu-Ming Wang, Zhe-Hao He, Wang Lv, Jian Hu
BACKGROUND: Negative-pressure wound therapy (NPWT) is the therapeutic management of traumatic soft-tissue wounds and infections. The efficacy of NPWT in the treatment of thoracic incision infection is unclear. We assess the effectiveness and safety of a novel facilitated NPWT for thoracic incision infection after esophagectomy. METHODS: Between Jan. 2013 and Mar. 2016, 380 patients underwent open esophagectomy in our department. Forty-five patients with thoracic incision infection were retrospectively reviewed...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28520603/does-negative-pressure-wound-therapy-for-the-open-abdomen-benefit-the-patient-a-retrospective-cohort-study
#4
Bojan Krebs, Tomaž Jagrič
OBJECTIVE: Negative-pressure wound therapy (NPWT) is the most modern and sophisticated method of temporary abdominal closure. The aim of the study was to determine the significant predictors for mortality in patients with NPWT. SETTING: University Clinical Centre Maribor, Slovenia MATERIALS AND METHODS:: The authors performed a retrospective cohort study of all patients treated with NPWT between January 1, 2011, and December 31, 2014. RESULTS: In the univariate analysis, the type of wound closure, more than 7 NPWT changes, the total days with NPWT, and time to wound closure were significantly associated with death of the patient...
June 2017: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/28515369/effect-of-reverse-vessel-remodeling-on-regression-of-coronary-atherosclerosis-in-patients-treated-with-aggressive-lipid-and-blood-pressure-lowering-therapy%C3%A3-insight-from-million-study
#5
Tadatsugu Gamou, Kenji Sakata, Hayato Tada, Tetsuo Konno, Kenshi Hayashi, Hidekazu Ino, Masakazu Yamagishi, Masa-Aki Kawashiri
BACKGROUND: The MILLION study, a prospective randomized multicenter study, revealed that lipid and blood pressure (BP)-lowering therapy resulted in regression of coronary plaque as determined by intravascular ultrasound (IVUS). In the present study we performed additional analysis to investigate the associated factors with regression of coronary plaque.Methods and Results:We investigated serial 3D IVUS images from 68 patients in the MILLION study. Standard IVUS parameters were assessed at both baseline and follow-up (18-24 months)...
May 17, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28508099/giant-congenital-melanocytic-nevi-and-malignant-transformation-a-case-for-early-radical-intervention
#6
Christopher R Maguire, Ryan Livingston, Gael E Phillips, Roy M Kimble
The purpose of this paper is to highlight the risk of early malignant transformation in infants with giant congenital melanocytic nevi (GN) and demonstrate the potential for earlier intervention with aggressive surgery. We describe the case of a child born with a GN who developed a metastatic melanoma early in life, despite early commencement of resection of the nevus. This is contrasted against a second case of a child in which a more radical management was conducted. Despite early commencement of serial resection of the GN, the first child in this series died of metastatic melanoma prior to complete excision of the nevus...
May 15, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28502075/vacuum-assisted-wound-closure-and-mesh-mediated-fascial-traction-for-open-abdomen-therapy-a-systematic-review
#7
Stefan Acosta, Martin Björck, Ulf Petersson
BACKGROUND: The aim of this paper was to review the literature on vacuum-assisted wound closure and mesh-mediated fascial traction (VAWCM) in open abdomen therapy. It was designed as systematic review of observational studies. METHODS: A Pub Med, EMBASE and Cochrane search from 2007/01-2016/07 was performed combining the Medical Subject Headings "vacuum", "mesh-mediated fascial traction", "temporary abdominal closure", "delayed abdominal closure", "open abdomen", "abdominal compartment syndrome", "negative pressure wound therapy" or "vacuum assisted wound closure"...
May 14, 2017: Anaesthesiology Intensive Therapy
https://www.readbyqxmd.com/read/28498266/use-of-positive-airway-pressure-following-middle-ear-surgery-a-practice-survey-of-otologists
#8
Douglas S Ruhl, Anthony M Tolisano, Bradley W Kesser, George T Hashisaki, Macario Camacho
BACKGROUND: Positive airway pressure (PAP) devices are used as treatment for obstructive sleep apnea (OSA). PAP may increase middle ear pressure which is of interest to otologic surgeons. There is a lack of data to guide management of PAP therapy after middle ear surgery. OBJECTIVE: To elucidate how otologic surgeons manage PAP in their patients after ear surgery. STUDY DESIGN: A survey e-mailed to practicing members of the American Neurotology Society...
May 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28489634/effects-of-negative-pressure-wound-therapy-on-primary-closed-defects-after-superficial-circumflex-iliac-artery-perforator-scip-flap-harvest
#9
Hyun Suk Suh, Min Young Jang, Joon Pio Hong
No abstract text is available yet for this article.
March 8, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28489630/-effects-of-incisional-negative-pressure-wound-therapy-on-primary-closed-defects-after-superficial-circumflex-iliac-artery-perforator-flap-harvest-randomized-controlled-study
#10
Panxi Yu, Xiaonan Yang, Zuoliang Qi
No abstract text is available yet for this article.
March 8, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28489215/negative-pressure-therapy-for-the-treatment-of-complex-wounds
#11
Renan Victor Kümpel Schmidt Lima, Pedro Soler Coltro, Jayme Adriano Farina
The objective of this study is to evaluate the effectiveness of negative pressure therapy (NPT) in the treatment of complex wounds, with emphasis on its mechanisms of action and main therapeutic indications. We searched the Pubmed / Medline database for articles published from 1997 to 2016, and selected the most relevant ones. The mechanisms of action of NPT involveboth physical effects, such as increased perfusion, control of edema and exudate, reduction of wound dimensions and bacterial clearance, and biological ones, such as the stimulation of granulation tissue formation, microdeformations and reduction of Inflammatory response...
January 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28479439/excessive-wound-fluid-discharge-during-retroperitoneal-negative-pressure-wound-therapy
#12
Fankhauser Christian Daniel, Hermanns Thomas, Hasse Barbara, Rancic Zoran
We report a case of a 66-year-old man with an excessive wound fluid discharge during negative pressure wound therapy (NWPT) in the retroperitoneal space. Creatinine concentration of the unclear fluid and a subsequent late phase computed tomography (CT) confirmed the diagnosis of a urinary fistula. NWPT was terminated and the patient was successfully treated with a nephrostomy combined with a retrograde double J stent and a Foley catheter.
May 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28475562/leukocyte-adhesion-as-an-indicator-of-oxygenator-thrombosis-during-extracorporeal-membrane-oxygenation-therapy
#13
Julius Wilm, Alois Philipp, Thomas Müller, Andre Bredthauer, Otto Gleich, Christof Schmid, Karla Lehle
Thrombosis is the most common technical complication with extracorporeal membrane oxygenation (ECMO). Accumulations of leukocytes on the gas exchange membranes within a membrane oxygenator (MO) may initiate thrombosis and influence outcome. MOs (n = 41) were removed routinely from adult patients on ECMO, preserved, and analyzed for their cellular deposits using nuclear (4',6-diamidino-2-phenylindole) and cell type-specific markers (CD45; von Willebrand factor, vWF). The extent of cellular colonization was correlated with patient data...
May 4, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28475440/the-effect-of-negative-pressure-wound-therapy-with-antibacterial-dressings-or-antiseptics-on-an-in-vitro-wound-model
#14
J Matiasek, K J Domig, G Djedovic, R Babeluk, O Assadian
OBJECTIVE: The aim of this study was to investigate the bacterial bioburden in experimental in vitro wounds during the application of conventional negative pressure wound therapy (NPWT), with and without antimicrobial dressings (polyhexanide, silver), against NPWT instillation of octenidine. METHOD: Experimental wounds produced in an in vitro porcine wound model were homogenously contaminated with bacterial suspension and treated with NPWT and different options...
May 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28472817/fistula-isolation-and-the-use-of-negative-pressure-to-promote-wound-healing-a-case-study
#15
Kersten E Reider
BACKGROUND: A 54-year-old morbidly obese woman with a small bowel obstruction and large ventral hernia was admitted to hospital. She underwent an exploratory laparotomy, lysis of adhesions, and ventral hernia repair with mesh placement. She subsequently developed an enteroatmospheric fistula; several months of hospital care was required to effectively manage the wound and contain effluent from the fistula. METHODS: Several approaches were used to manage output from the fistula during her hospital course...
May 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28460496/blood-pressure-may-be-associated-with-arterial-collateralization-in-anterior-circulation-ischemic-stroke-before-acute-reperfusion-therapy
#16
Beisi Jiang, Leonid Churilov, Lasheta Kanesan, Richard Dowling, Peter Mitchell, Qiang Dong, Stephen Davis, Bernard Yan
Background and Purpose: Leptomeningeal collaterals maintain arterial perfusion in acute arterial occlusion but may fluctuate subject to arterial blood pressure (ABP). We aim to investigate the relationship between ABP and collaterals as assessed by computer tomography (CT) perfusion in acute ischemic stroke. Methods: We retrospectively analyzed acute anterior circulation ischemic stroke patients with CT perfusion from 2009 to 2014. Collateral status using relative filling time delay (rFTD) determined by time delay of collateral-derived contrast opacification within the Sylvian fissure, from 0 seconds to unlimited count...
May 2, 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28460201/deep-sternal-wound-infections-a-severe-complication-after-cardiac-surgery
#17
A Morgante, F Romeo
Sternal Wound Infections (SWI) represent a dangerous complication after cardiac surgery entailing significantly longer hospital stays and worse short-term survival, especially in case of deep infections (DSWI) with the onset of osteomielitis or mediastinitis. The real incidence of SWI can be estimated between 0.25% and 10%; among the risk factors for sternal dehiscences after a longitudinal median sternotomy, several experiences underline the role of diabetes as an independent risk factor for post-operative infections, especially in patients affected by COPD with higher BMI...
January 2017: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/28459958/biased-ligand-of-the-angiotensin-ii-type-1-receptor-in-patients-with-acute-heart-failure-a-randomized-double-blind-placebo-controlled-phase-iib-dose-ranging-trial-blast-ahf
#18
Peter S Pang, Javed Butler, Sean P Collins, Gad Cotter, Beth A Davison, Justin A Ezekowitz, Gerasimos Filippatos, Phillip D Levy, Marco Metra, Piotr Ponikowski, John R Teerlink, Adriaan A Voors, David Bharucha, Kathleen Goin, David G Soergel, G Michael Felker
Aims: Currently, no acute heart failure (AHF) therapy definitively improves outcomes. Reducing morbidity and mortality from acute heart failure (AHF) remains an unmet need. TRV027 is a novel 'biased' ligand of the angiotensin II type 1 receptor (AT1R), selectively antagonizing the negative effects of angiotensin II, while preserving the potential pro-contractility effects of AT1R stimulation. BLAST-AHF was designed to determine the safety, efficacy, and optimal dose of TRV027 to advance into future studies...
April 27, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28459717/expression-of-mmp-8-in-pressure-injuries-in-spinal-cord-injury-patients-managed-by-negative-pressure-wound-therapy-or-conventional-wound-care-a-randomized-controlled-trial
#19
Mukesh Kumar Dwivedi, Amit Kumar Bhagat, Rajeshwar Nath Srivastava, Amita Jain, Kavita Baghel, Saloni Raj
PURPOSE: The purpose of this study was to assess the level of matrix metalloproteinase-8 (MMP-8) and wound-healing outcome measures (length, width, and depth, exudate amount, and tissue type) in pressure injuries (PIs) of spinal cord-injured patients treated with negative pressure wound therapy (NPWT) using a novel negative pressure device versus PI treated with wet to moist gauze (conventional wound care). DESIGN: Randomized controlled trial. SUBJECTS AND SETTING: Forty-four spinal cord-injured patients with stage 3 and 4 sacral PI participated in the study...
April 28, 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28459181/effect-of-negative-pressure-wound-therapy-cellular-fibronectin-and-transforming-growth-factor-%C3%AE-1-expression-in-diabetic-foot-wounds
#20
Shao Ling Yang, Lv Yun Zhu, Rui Han, Lei Lei Sun, Jing Tao Dou
BACKGROUND: Chronic diabetic foot wounds are a leading cause of amputation, morbidity, and hospitalization for patients with diabetes. Negative-pressure wound therapy (NPWT) can putatively facilitate wound healing, but the underlying mechanisms remain unclear. Cellular fibronectin (cFN) and transforming growth factor-β1 (TGF-β1) play an important role in wound healing. This prospective randomized controlled trial evaluated the effects of NPWT on the production of cFN and the expression of TGF-β1 in diabetic foot wounds of patients...
April 1, 2017: Foot & Ankle International
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