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https://www.readbyqxmd.com/read/28797424/retrograde-chronic-total-occlusion-percutaneous-coronary-intervention-through-ipsilateral-collateral-channels-a-multicenter-registry
#1
Lorenzo Azzalini, Pierfrancesco Agostoni, Susanna Benincasa, Paul Knaapen, Stefan P Schumacher, Joseph Dens, Joren Maeremans, Adriaan O Kraaijeveld, Leo Timmers, Michael Behnes, Ibrahim Akin, Aurel Toma, Franz-Josef Neumann, Antonio Colombo, Mauro Carlino, Kambis Mashayekhi
OBJECTIVES: The aim of this study was to describe the procedural aspects and outcomes of retrograde chronic total occlusion (CTO) percutaneous coronary intervention (PCI) through ipsilateral collateral channels (ILCs). BACKGROUND: Retrograde CTO PCI via ILCs is rarely performed, usually when no other retrograde options exist, and available evidence derives mostly from case reports. METHODS: A large retrospective multinational registry was compiled, including all consecutive patients undergoing retrograde CTO PCI through ILCs at 6 centers between September 2011 and October 2016...
August 14, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28776069/porcine-arteriogenesis-based-on-vasa-vasorum-in-a-novel-semi-acute-occlusion-model-using-high-resolution-imaging
#2
Jonathan M Harnoss, Florian Krackhardt, Zully Ritter, Susanne Granzow, Dieter Felsenberg, Konrad Neumann, Lilach O Lerman, Fabian Riediger, Philipp Hillmeister, Peter Bramlage, Ivo R Buschmann
Bridging collaterals (BC) develop in several chronic total artery occlusion diseases, and can prevent extensive myocardial necrosis. Yet, their origin, growth process, and histo-morphology are still unclear. Since vasa vasorum (VV) may take part in collateralization, we hypothesized that VV are the basis for BCs. To comprehensively investigate this arteriogenesis process, we used high-resolution imaging, including corrosion casts, post-mortem angiography with stereoscopy, micro-CT, and immunohistology, in combination with a novel semi-acute vessel occlusion model...
August 3, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28738486/-association-between-collateral-circulation-and-myocardial-viability-evaluated-by-cardiac-magnetic-resonance-imaging-in-patients-with-coronary-artery-chronic-total-occlusion
#3
J N Li, L J Zhang, Y He, Y L Chen, R C Huang, S Z Lyu, X T Song
Objective: Late gadolinium enhancement(LGE) cardiac magnetic resonance imaging(CMR) was used to evaluate the myocardial viability of chronic total occlusion(CTO) in patients with coronary heart disease and to observe the relationship between collateral circulation and myocardium viability in these patients. Methods: This retrospective study included 40 patients with CTO diagnosed by invasive coronary angiography (CAG) from September 2015 to June 2016 in our department, all patients performed CMR examination within one week after CAG...
July 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/28724418/improved-recovery-of-regional-left-ventricular-function-after-pci-of-chronic-total-occlusion-in-stemi-patients-a-cardiovascular-magnetic-resonance-study-of-the-randomized-controlled-explore-trial
#4
Joëlle Elias, Ivo M van Dongen, Loes P Hoebers, Dagmar M Ouweneel, Bimmer E P M Claessen, Truls Råmunddal, Peep Laanmets, Erlend Eriksen, René J van der Schaaf, Dan Ioanes, Robin Nijveldt, Jan G Tijssen, Alexander Hirsch, José P S Henriques
BACKGROUND: The Evaluating Xience and left ventricular function in PCI on occlusiOns afteR STEMI (EXPLORE) trial did not show a significant benefit of percutaneous coronary intervention (PCI) of the concurrent chronic total occlusion (CTO) in ST-segment elevation myocardial infarction (STEMI) patients on global left ventricular (LV) systolic function. However a possible treatment effect will be most pronounced in the CTO territory. Therefore, we aimed to study the effect of CTO PCI compared to no-CTO PCI on the recovery of regional LV function, particularly in the CTO territory...
July 19, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28712815/asymptomatic-carotid-stenosis-is-associated-with-cognitive%C3%A2-impairment
#5
Brajesh K Lal, Moira C Dux, Siddhartha Sikdar, Carly Goldstein, Amir A Khan, John Yokemick, Limin Zhao
BACKGROUND: Cerebrovascular risk factors (eg, hypertension, coronary artery disease) and stroke can lead to vascular cognitive impairment. The Asymptomatic Carotid Stenosis and Cognitive Function study evaluated the isolated impact of asymptomatic carotid stenosis (no prior ipsilateral or contralateral stroke or transient ischemic attack) on cognitive function. Cerebrovascular hemodynamic and carotid plaque characteristics were analyzed to elucidate potential mechanisms affecting cognition...
July 13, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28701611/the-utility-of-targeted-perioperative-transthoracic-echocardiography-in-managing-an-adult-patient-with-anomalous-origin-of-the-left-coronary-artery-pulmonary-artery-for-noncardiac-surgery
#6
Anudeep Jafra, Suman Arora, Aveek Jayant
Congenital coronary artery anomalies as a whole are uncommon. Abnormal origin of the left coronary artery from the pulmonary artery (ALCAPA) is probably the most common congenital coronary defect. An overwhelming majority of the patients with untreated ALCAPA do not survive to adulthood. As yet, there is no consensus on the management of adults with ALCAPA. We describe a patient with breast malignancy and incidentally detected ALCAPA; primacy was given to treatment of the oncologic condition as a first step...
July 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28700405/characterization-of-viability-scarring-and-hibernation-of-the-myocardium-supplied-by-epicardial-coronary-arteries-with-low-flow-grades
#7
Abdallah Al-Mohammad, Murdoch Y Norton, Andrew E Welch, Stephen Walton
OBJECTIVE: The aim of this study was to analyse the relationship between reduced coronary artery flow and myocardial viability, scarring and hibernation. PATIENTS AND METHODS: Coronary flow grades and collateral vessels were scored using the thrombolysis in myocardial infarction trial (TIMI) and the Rentrop and Cohen scoring systems, respectively. N-ammonia and fluorine-18-fluorodeoxyglucose (F-FDG) are the perfusion and metabolic markers on PET, respectively. The left ventricle was divided into three coronary territories...
August 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28700032/lipoprotein-a-as-a-predictor-of-poor-collateral-circulation-in-patients-with-chronic-stable-coronary-heart-disease
#8
Y Fan, J-S Hu, F Guo, Z-B Lu, H Xia
As a mechanism compensating for obstructive coronary artery disease, coronary collateral circulation (CCC) has attracted cardiologists for a long time to explore its potential impact. In the present study, Chinese patients suffering from ≥95% coronary stenosis, as diagnosed by angiography, have been investigated for the correlation between CCC and lipoprotein(a) [Lp(a)] levels. A cohort of 654 patients was divided into four categories according to Rentrop grades 0, 1, 2, and 3. Lp(a) levels were divided into model 1, discretized with critical values of 33 and 66%, and model 2, discretized with a cutoff value of 30...
July 10, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/28685580/association-of-igf-1-with-coronary-collateral-circulation-in-stable-coronary-artery-disease
#9
Harun Kundi, Murat Gok, Emrullah Kiziltunc, Mustafa Cetin, Ender Ornek
AIM: The aim of the present study is to evaluate the relationship between coronary collateral circulation (CCC) grade and serum IGF-1 levels in patients diagnosed with stable coronary artery disease. METHODS: Totally, 190 consecutive patients with stable coronary artery disease who underwent coronary angiography were included in this study. RESULTS: The patients with good CCC had significantly higher IGF-1 levels compared with the poor ones...
July 7, 2017: Biomarkers in Medicine
https://www.readbyqxmd.com/read/28678145/novel-molecular-targets-for-coronary-angiogenesis-and-ischemic-heart-disease
#10
Brittany A Potz, Anshul B Parulkar, Ruhul M Abid, Neel R Sodha, Frank W Sellke
Coronary artery disease (CAD) is the number one cause of death among men and women in the USA. Genetic predisposition and environmental factors lead to the development of atherosclerotic plaques in the vessel walls of the coronary arteries, resulting in decreased myocardial perfusion. Treatment includes a combination of revascularization procedures and medical therapy. Because of the high surgical risk of many of the patients undergoing revascularization procedures, medical therapies to reduce ischemic disease are an area of active research...
July 3, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28678144/relationship-of-mean-platelet-volume-to-lymphocyte-ratio-and-coronary-collateral-circulation-in-patients-with-stable-angina-pectoris
#11
Ender Ornek, Alparslan Kurtul
BACKGROUND: In patients with coronary artery disease, coronary collateral circulation (CCC) develops as an adaptation to ischemia and contributes toward reduction of cardiovascular events. Recently, the mean platelet volume-to-lymphocyte ratio (MPVLR) has emerged as a novel and readily available marker of inflammation and thrombosis. This study aimed to investigate the relationship between MPVLR and development of CCC. PATIENTS AND METHODS: A total of 332 patients with stable angina pectoris undergoing coronary arteriography were enrolled and divided on the basis of the development of CCC into two groups: group with adequate CCC (n=243) and group with impaired CCC (n=89)...
September 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28651802/echocardiographic-diagnosis-surgical-treatment-and-outcomes-of-anomalous-left-coronary-artery-from-the-pulmonary-artery
#12
Shivani G Patel, Michele A Frommelt, Peter C Frommelt, Shelby Kutty, Jonathan W Cramer
BACKGROUND: Anomalous left coronary artery from the pulmonary artery (ALCAPA) is a rare condition that can be difficult to diagnose by echocardiography alone. The purpose of this study was to describe the clinical and echocardiographic presentation of ALCAPA, create a set of critical echocardiographic diagnostic criteria, and report outcomes. METHODS: A retrospective review was conducted of all patients diagnosed with isolated ALCAPA at two major cardiac centers between 1990 and 2015...
June 23, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28651297/anomalous-origin-of-the-left-main-coronary-artery-arising-from-the-left-ventricular-outflow-tract-with-a-retro-aortic-collateral-vessel
#13
Asad Khan, Jason Audlin, Santiago Miro, Debanik Chaudhuri, Robert Dunton
No abstract text is available yet for this article.
June 26, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28644211/the-relationship-between-fasting-blood-glucose-variability-and-coronary-artery-collateral-formation-in-type-2-diabetes-patients-with-coronary-artery-disease
#14
Gang Cheng, Hilda Mahmoudi, Binna Chokshi, Marlena Fernandez, Vahid Kazemi, Nader Lamaa
BACKGROUND: Coronary collaterals are an alternative source of blood supply to ischemic myocardium. Well-developed coronary collateral arteries in patients with coronary artery disease (CAD) limit the size of acute myocardial infarction and improves survival. The aim of this study was to investigate the relationship between glycemic variability and coronary collateral formation in patients with type 2 diabetes mellitus and CAD. METHODS: Consecutive patients undergoing percutaneous coronary intervention or coronary artery bypass grafting procedures were studied...
September 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28643216/spontaneous-coronary-artery-dissection-with-a-collateral-vessel
#15
Toshihiro Suga, Takashi Hatori, Keita Oyama, Yuko Suga, Kunihiko Imai, Younosuke Kitahara
No abstract text is available yet for this article.
June 22, 2017: Cardiovascular Intervention and Therapeutics
https://www.readbyqxmd.com/read/28639006/angiogenic-growth-factors-in-myocardial-infarction-a-critical-appraisal
#16
REVIEW
Hemalatha Thiagarajan, UmaMaheswari Thiyagamoorthy, Iswariya Shanmugham, Gunadharini Dharmalingam Nandagopal, Anbukkarasi Kaliyaperumal
In the recent past, substantial advances have been made in the treatment of myocardial infarction (MI). Despite the impact of these positive developments, MI remains to be a leading cause of morbidity as well as mortality. An interesting hypothesis is that the development of new blood vessels (angiogenesis) or the remodeling of preexisting collaterals may form natural bypasses that could compensate for the occlusion of an epicardial coronary artery. A number of angiogenic factors are proven to be elicited during MI...
June 21, 2017: Heart Failure Reviews
https://www.readbyqxmd.com/read/28637776/targeting-of-extracellular-rna-reduces-edema-formation-and-infarct-size-and-improves-survival-after-myocardial-infarction-in-mice
#17
Philipp Stieger, Jan-Marcus Daniel, Christiane Thölen, Jochen Dutzmann, Kai Knöpp, Dursun Gündüz, Muhammad Aslam, Marian Kampschulte, Alexander Langheinrich, Silvia Fischer, Hector Cabrera-Fuentes, Yong Wang, Kai C Wollert, Johann Bauersachs, Rüdiger Braun-Dullaeus, Klaus T Preissner, Daniel G Sedding
BACKGROUND: Following myocardial infarction (MI), peri-infarct myocardial edema formation further impairs cardiac function. Extracellular RNA (eRNA) released from injured cells strongly increases vascular permeability. This study aimed to assess the role of eRNA in MI-induced cardiac edema formation, infarct size, cardiac function, and survival after acute MI and to evaluate the therapeutic potential of ribonuclease 1 (RNase-1) treatment as an eRNA-degrading intervention. METHODS AND RESULTS: C57BL/6J mice were subjected to MI by permanent ligation of the left anterior descending coronary artery...
June 21, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28617303/prognostic-value-of-coronary-collaterals-in-patients-with-acute-coronary-syndromes
#18
Alparslan Kurtul, Selcuk Ozturk
BACKGROUND: The presence of good coronary collateral circulation (CCC) can protect and preserve myocardium from ischemia, increase myocardial contractility, and reduce adverse clinical events. However, its impact on mortality is still a topic of debate, particularly in acute coronary syndrome (ACS). The aim of this study was to investigate the association of CCC with cardiac risk factors and in-hospital mortality in patients hospitalized with a diagnosis of ACS. METHODS: The study population included 2286 patients with ACS who underwent coronary angiography and were found to have at least 90% significant lesion in at least one major coronary artery...
August 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28610440/circumflex-coronary-artery-originating-from-the-right-pulmonary-artery-in-adult
#19
Ahmet Daylan, Serkan Ertugay, Anıl Ziya Apaydın, Emrah Oğuz
Anomalous origin of the circumflex coronary artery from the right pulmonary artery is rare, and symptoms are related to the collateralization and amount of myocardium that it supplies. A 50-year-old woman with severe bicuspid aortic valve stenosis had the diagnosis of anomalous origin of the circumflex coronary artery from the right pulmonary artery before valve replacement. Ligation and division of the circumflex coronary artery was performed. Myocardial ischemia was not observed. The patient was discharged after an uneventful recovery...
January 1, 2017: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/28595879/predictors-of-successful-hybrid-approach-chronic-total-coronary-artery-occlusion%C3%A2-stenting-an-improved-model-with-novel-correlates
#20
Stephen G Ellis, M Nicholas Burke, M Bilal Murad, John J Graham, Ramy Badawi, Catelin Toma, Henry Meltser, Ravi Nair, Chris Buller, Patrick L Whitlow
OBJECTIVES: The aim of this study was to develop a hybrid approach-specific model to predict chronic total coronary artery occlusion (CTO) percutaneous coronary intervention success, useful for experienced but not ultra-high-volume operators. BACKGROUND: CTO percutaneous coronary intervention success rates vary widely and have improved with the "hybrid approach," but current predictive models for success have major limitations. METHODS: Data were obtained from consecutively attempted patients from 7 clinical sites (9 operators, mean annual CTO volume 61 ± 17 cases)...
June 12, 2017: JACC. Cardiovascular Interventions
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