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Coronary collateral

Ying Shen, Feng Hua Ding, Rui Yan Zhang, Qi Zhang, Lin Lu, Wei Feng Shen
The data presented here support the research article "Association of serum mimecan with angiographic coronary collateralization in patients with stable coronary artery disease and chronic total occlusion" (Shen et al., 2016) [1] where elevated circulating mimecan levels reflected poor angiographic coronary collateralization in such patients. The data included in this article are composed by one figure and consist of (1) validation of serum mimecan measurement by assessing inter- and intra-assay variability in 45 samples; (2) findings on the relation of clinical and angiographic characteristics and biochemical parameters to coronary collateralization in 559 patients; (3) the diagnostic value of serum mimecan for poor collateralization, which was derived from plotting receiver-operating characteristic curves and logistic regression analysis...
December 2016: Data in Brief
Maurits R Hollander, Maarten A H van Leeuwen, Dirk van der Heijden, Vincent M N Keizer, Peter M van de Ven, Sander J J IJsselmuiden, Nicolas M Van Mieghem, Giovanni Amoroso, Marco J P F Ritt, Paul Knaapen, Niels van Royen
AIMS: During transradial coronary catheterization the radial artery is functionally occluded and hand perfusion depends on the collateral circulation. Nexfin is a simple, non-invasive technique to measure digital arterial pressure and could serve to quantify the palmar collateral circulation. Potentially, inter-individual differences in the extent of collateralization are related to perfusion and function after transradial intervention. METHODS AND RESULTS: In total 85 adults were included (18 healthy volunteers; 67 patients who underwent transradial catheterization)...
October 11, 2016: EuroIntervention
Mehmet Kadri Akboga, Ridvan Yalcin, Asife Sahinarslan, Canan Yilmaz Demirtas, Adnan Abaci
OBJECTIVE: Many studies have revealed a role of YKL-40 as a new inflammatory biomarker in angiogenesis, inflammation, atherosclerosis and cardiovascular events. Thus, the aim of this study was to investigate the association of serum YKL-40 level with coronary collateral development and SYNTAX score in patients with stable coronary artery disease. METHODS: A total of 165 patients who had ≥90% stenosis in at least one major coronary artery were prospectively enrolled in the study...
September 17, 2016: International Journal of Cardiology
Nasirudeen Ajayi, Ebrahim Vanker, Kapil Sewsaran Satyapal
BACKGROUND: In obstructive coronary artery disease (CAD), coronary collateral arteries serve as alternative conduits for blood flow to the myocardial tissue supplied by the obstructed vessel(s). Therefore, they are a "natural coronary arterial bypass" to the region supplied by the obstructed vessels. This study aims to determine the influence of demographic and morphologic coronary arterial factors on coronary collateral development in coronary arterial obstruction. MATERIALS AND METHODS: The study group was selected from the coronary angiographic records of 2029 consecutive patients (mean age: 59 ± 12 years)...
September 26, 2016: Folia Morphologica (Warsz)
Yoriyasu Suzuki, Makoto Muto, Masahisa Yamane, Toshiya Muramatsu, Atsunori Okamura, Yasumi Igarashi, Tsutomu Fujita, Shigeru Nakamura, Akitsugu Oida, Etsuo Tsuchikane
OBJECTIVES: To evaluate factors for predicting retrograde CTO-PCI failure after successful collateral channel crossing. BACKGROUND: Successful guidewire/catheter collateral channel crossing is important for the retrograde approach in percutaneous coronary intervention (PCI) for chronic total occlusion (CTO). METHODS: A total of 5984 CTO-PCI procedures performed in 45 centers in Japan from 2009 to 2012 were studied. The retrograde approach was used in 1656 CTO-PCIs (27...
September 21, 2016: Catheterization and Cardiovascular Interventions
Samim Emet, Ali Elitok, Imran Onur, Mehmet Kocaaga, Ahmet Kaya Bilge, Huseyin Oflaz, Berrin Umman, Aytac Oncul, Zehra Bugra, Kamil Adalet, Fehmi Mercanoglu
Angiogenesis and arteriogenesis have a crucial role in the formation of coronary collateral vessels. It has been shown that endocan and vascular cell adhesion molecule-1 (VCAM-1) are potential angiogenetic factors. We investigated the relationship between serum endocan levels and grade of coronary collaterals, and also the correlation of endocan levels with serum VCAM-1 levels. Patients with stable angina and at least one total coronary occlusion at invasive coronary angiography were included in our study. Collateral degree was graded according to Rentrop and Cohen's classification...
September 16, 2016: Journal of Thrombosis and Thrombolysis
Santosh Kumar Sinha, Dibbendhu Khanra, Mukesh Jitendra Jha, Karandeep Singh, Mahamdulla Razi, Amit Goel, Vikas Mishra, Mohammad Asif, Mohit Sachan, Nasar Afdaali, Ashutosh Kumar, Ramesh Thakur, Vinay Krishna, Umeshwar Pandey, Chandra Mohan Varma
ALCAPA syndrome (anomalous origin of the left coronary artery from the pulmonary artery) is a rare disease but lethal with clinical expression from myocardial infarction, congestive heart failure to death during early infancy and unusual survival to adulthood. We report a 73-year-old woman with ALCAPA who presented with exertional dyspnea (NYHA functional class II) over past 2 years. Physical examination revealed soft S, long mid diastolic rumbling murmur and apical pan-systolic murmur. Electrocardiography displayed biatrial enlargement and poor R progression and normal sinus rhythm...
October 2016: Journal of Clinical Medicine Research
Serkan Akdag, Aytac Akyol, Muntecep Asker, Fatih Ozturk, Hasan Ali Gumrukcuoglu
INTRODUCTION: Recently, platelet-to-lymphocyte ratio (PLR) has emerged as a significant inflammatory marker and a novel predictor of major adverse consequences in cardiovascular disease. AIM: In this study, we aimed to explore the relationship between PLR and coronary collateral circulation (CCC) in patients with non-ST elevation myocardial infarction (NSTEMI). MATERIAL AND METHODS: Clinical and laboratory data of 386 patients who underwent coronary angiography were evaluated retrospectively...
2016: Postępy W Kardiologii Interwencyjnej, Advances in Interventional Cardiology
Vincent Amoah, Benjamin Wrigley, Eric Holroyd, Andrew Smallwood, Angel L Armesilla, Alan Nevill, James Cotton
INTRODUCTION: We evaluated the association between two single nucleotide polymorphisms of the vascular endothelial growth factor gene and one of the hypoxia-inducible factor-1α gene and the degree of coronary collateral formation in patients with a coronary chronic total occlusion. METHODS: Totally, 98 patients with symptomatic coronary artery disease and a chronic total occlusion observed during coronary angiography were recruited. Genotyping of two vascular endothelial growth factor promoter single nucleotide polymorphisms (-152G>A and -165C>T) and the C1772T single nucleotide polymorphism of hypoxia-inducible factor-1α were performed using polymerase chain reaction and restriction fragment length polymorphism analysis...
2016: SAGE Open Medicine
Wijnand J Stuijfzand, Roel S Driessen, Pieter G Raijmakers, Mischa T Rijnierse, Joren Maeremans, Maurits R Hollander, Adriaan A Lammertsma, Albert C van Rossum, Jo Dens, Alexander Nap, Niels van Royen, Paul Knaapen
AIMS: Previous studies on invasive assessment of collateral function in patients with a chronic total occlusion (CTO) have displayed only a limited increase in collateral flow and high occurrence of coronary steal during pharmacological stress. This could question the necessity for ischaemia testing prior to revascularization of CTOs in the presence of myocardial viability. The purpose of the present study was to determine the prevalence of perfusion impairments in patients with a CTO as assessed by [(15)O]H2O positron emission tomography (PET)...
September 1, 2016: European Heart Journal Cardiovascular Imaging
Ashish P Saini, Stephen E Cyran, Steven M Ettinger, Linda B Pauliks
A 15-year-old boy with transposition of the great arteries (TGA) and neonatal arterial switch operation (ASO) presented with complete occlusion of the left main coronary artery (LMCA). Intra-operatively, an intramural left coronary artery was identified. Therefore, since age 7 years he had a series of screening exercise stress tests. At 13 years old, he had 3 to 4 mm ST segment depression in the infero-lateral leads without symptoms. This progressed to 4.2 mm inferior ST segment depression at 15 years old with normal stress echocardiogram...
August 16, 2016: World Journal of Clinical Cases
Zülküf Karahan, Bernas Altıntaş, Murat Uğurlu, İlyas Kaya, Berzal Uçaman, Ali Veysel Uluğ, Rojhat Altındağ, Yakup Altaş, Mehmet Şahin Adıyaman, Önder Öztürk
BACKGROUND: It is known that QRS duration is related to prognosis in acute myocardial infarction. The relation between QRS duration and coronary collateral circulation is uncertain. In the present study, we aimed to determine the relation between QRS duration and coronary collateral circulation in patients admitted with acute myocardial infarction. METHODS: The present study was composed of 109 consecutive patients with acute myocardial infarction. All patients had total occlusion in the left anterior descending coronary artery...
January 2016: JRSM Cardiovascular Disease
Chun Yang, Xiu Han, Xin Jiang, Xinjun Lei, Ling Bai, Feng Xu
Coronary collateral circulation is an alternative source of blood supply to the myocardium in the presence of chronic total coronary occlusion (CTO). C-X-C motif chemokine receptor 4 (CXCR4) signaling usually contributes to neovascularization. Here, we investigate the relation between CXCR4 levels in peripheral blood CD34+ cells and the formation of angiographic coronary collaterals and determine the risk factors that affect CXCR4 expression in patients with CTO. Demographic, biochemical, and angiographic variables were collected from 324 patients with CTO and 90 negative controls...
October 15, 2016: American Journal of Cardiology
I O Yuksel, G Cagirci, E Koklu, A Yilmaz, S Kucukseymen, H Y Ellidag, S Cay, N Yilmaz, S Arslan
OBJECTIVE: Erythropoietin (EPO) improves cardiac function and induces neovascularisation in post-myocardial infarction heart failure. The aim of this study was to analyse the association between the serum erythropoietin level and coronary collateral development in patients with coronary artery disease and chronic total occlusion. METHODS: A total of 168 patients consisting of 117 with coronary artery disease (CAD, (62 with chronic total occlusion (CTO), 55 without CTO)) and 51 with healthy coronary arteries were included in the study...
October 2016: Netherlands Heart Journal
Qing Qin, Juying Qian, Jianying Ma, Lei Ge, Junbo Ge
This study is aimed to investigate whether serum angiostatic factors (thrombospondin-1 [TSP-1] and endostatin) or angiogenic factors (angiopoietin-2 [Ang-2]) are related to coronary collateral vessel development in patients with chronic total occlusion (CTO).A total of 149 patients were enrolled in the study, and 39 patients with coronary artery disease but without significant stenosis were included in control group. In 110 patients with CTO lesion, 79 with Rentrop grades 2 to 3 collaterals were grouped as good collateral, while 31 with Rentrop grades 0 to 1 collaterals were grouped as poor collateral...
August 2016: Medicine (Baltimore)
Ying Shen, Feng Hua Ding, Rui Yan Zhang, Qi Zhang, Lin Lu, Wei Feng Shen
BACKGROUND AND AIMS: Mimecan/osteoglycin is identified as an emerging biomarker of coronary atherosclerosis. We investigated whether and to what extent serum mimecan reflects angiographic coronary collateralization in patients with stable coronary artery disease and chronic total occlusion. METHODS: Serum levels of mimecan were determined in 559 consecutive patients with stable angina and angiographic total occlusion of at least one major coronary artery. The degree of collaterals supplying the distal aspect of a total occlusion from the contra-lateral vessel was graded as poor (Rentrop score of 0 or 1) or good coronary collateralization (Rentrop score of 2 or 3)...
September 2016: Atherosclerosis
Andreas Borowski, Erhard Godehardt, Hannan Dalyanoglu
OBJECTIVE: Chronic totally occluded right coronary artery (CTO-RCA) often poses a problem in decision making for/against bypass grafting due to the lack of standardized indication criteria. The aim of the study was to investigate whether qualitative angiograms can be useful in decision making for/against surgical revascularization of CTO-RCA. METHODS: A retrospective cohort study was conducted with 69 patients who underwent elective CABG procedure, including single graft to the RCA...
August 8, 2016: General Thoracic and Cardiovascular Surgery
YuanHui Wang, Lei Zhang, Li Jia, Jing Liu, Kun Liu, QiZhen Feng, Qiang Wang
PURPOSE: Aerobic exercise may offer favorable effects for coronary perfusion in the myocardial ischemia area, although the underlying molecular mechanisms remain unclear. This study was designed to investigate the effect of aerobic exercise on the collateral circulation in the ischemia myocardium and to evaluate calcitonin gene-related peptide (CGRP) changes during this process. METHODS AND RESULTS: Wistar rats were randomly divided into 3 groups of 7 rats each: a sham operated group (Sham), a myocardial ischemia-only group (MI) and a MI plus aerobic exercise group (MI+AE)...
August 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Alessandro Iliceto, Sara Louise Berndt, Jaimi H Greenslade, William A Parsonage, Christopher Hammett, Martin Than, Tracey Hawkins, Kate Parker, Shannen O'Kane, Louise Cullen
OBJECTIVE: Obtaining an accurate medical history is essential in the assessment of patients, particularly in emergency department (ED) patients with acute chest pain, as there can be a time imperative for diagnosis and commencement of treatment. We aimed to evaluate reliability of patient-reported compared with physician-adjudicated medical history by assessing patient's recall and communication of personal events and its influence on the accuracy of the medical history. METHODS: A total of 776 patients presenting at ED with suspected cardiac chest pain were recruited...
September 2016: Critical Pathways in Cardiology
Si-Wan Choi, Ji Hye Han, Seon-Ah Jin, Mijoo Kim, Jae-Hwan Lee, Jin-Ok Jeong
Ventricular septal defect (VSD) is a lethal complication of myocardial infarction. The event occurs 2-8 days after an infarction and patients should undergo emergency surgical treatment. We report on successful device closure of post-infarction VSD. A previously healthy 66-year-old male was admitted with aggravated dyspnea. Echocardiography showed moderate left ventricular (LV) systolic dysfunction with akinesia of the left anterior descending (LAD) territory and muscular VSD size approximately 2 cm. Coronary angiography showed mid-LAD total occlusion without collaterals...
2016: Clinical Interventions in Aging
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