keyword
https://read.qxmd.com/read/38622540/shared-and-divergent-mental-health-characteristics-of-adnp-chd8-and-dyrk1a-related-neurodevelopmental-conditions
#1
JOURNAL ARTICLE
Emily Neuhaus, Hannah Rea, Elizabeth Jones, Hannah Benavidez, Conor Miles, Alana Whiting, Margaret Johansson, Curtis Eayrs, Evangeline C Kurtz-Nelson, Rachel Earl, Raphael A Bernier, Evan E Eichler
BACKGROUND: Neurodevelopmental conditions such as intellectual disability (ID) and autism spectrum disorder (ASD) can stem from a broad array of inherited and de novo genetic differences, with marked physiological and behavioral impacts. We currently know little about the psychiatric phenotypes of rare genetic variants associated with ASD, despite heightened risk of psychiatric concerns in ASD more broadly. Understanding behavioral features of these variants can identify shared versus specific phenotypes across gene groups, facilitate mechanistic models, and provide prognostic insights to inform clinical practice...
April 15, 2024: Journal of Neurodevelopmental Disorders
https://read.qxmd.com/read/38598041/identifying-risk-factors-for-attention-deficit-hyperactivity-disorder-adhd-a-public-health-concern-and-opportunity
#2
JOURNAL ARTICLE
Karyl Rattay, Lara R Robinson
Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders with significant individual and societal negative impacts of the disorder continuing into adulthood (Danielson et al. in Journal of Clinical Child and Adolescent Psychology, in press; Landes and London in Journal of Attention Disorders 25:3-13, 2021). Genetic and environmental risk (e.g., modifiable exposures such as prenatal tobacco exposure and child maltreatment) for ADHD is likely multifactorial (Faraone et al...
April 10, 2024: Prevention Science: the Official Journal of the Society for Prevention Research
https://read.qxmd.com/read/38532901/a-6-year-old-with-childhood-absence-epilepsy-and-motor-hyperactivity
#3
JOURNAL ARTICLE
Stéphane Auvin
A case study of a child with childhood absence epilepsy and hyperactivity introduces the discussion around the psychiatric diagnosis, differential considerations, and pharmacologic treatment options for ADHD/hyperactivity in children with epilepsy. Most of the time, ADHD in children with epilepsy is an inattentive form. The assessment emphasizes the need to differentiate ADHD symptoms from other psychiatric comorbidities. This is also crucial to evaluate when symptoms emerged, their impact on daily life, and if it could be a potential medication side effect...
2024: Epilepsy & behavior reports
https://read.qxmd.com/read/38506617/a-state-of-the-art-overview-of-candidate-diagnostic-biomarkers-for-attention-deficit-hyperactivity-disorder-adhd
#4
JOURNAL ARTICLE
Valeria Parlatini, Alessio Bellato, Alessandra Gabellone, Lucia Margari, Lucia Marzulli, Emilia Matera, Maria Giuseppina Petruzzelli, Marco Solmi, Christoph U Correll, Samuele Cortese
INTRODUCTION: Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental conditions and is highly heterogeneous in terms of symptom profile, associated cognitive deficits, comorbidities, and outcomes. Heterogeneity may also affect the ability to recognize and diagnose this condition. The diagnosis of ADHD is primarily clinical but there are increasing research efforts aiming at identifying biomarkers that can aid the diagnosis. AREAS COVERED: We first discuss the definition of biomarkers and the necessary research steps from discovery to implementation...
March 20, 2024: Expert Review of Molecular Diagnostics
https://read.qxmd.com/read/38483760/amygdala-volume-is-associated-with-adhd-risk-and-severity-beyond-comorbidities-in-adolescents-clinical-testing-of-brain-chart-reference-standards
#5
JOURNAL ARTICLE
Ádám Nárai, Petra Hermann, Alexandra Rádosi, Pál Vakli, Béla Weiss, János M Réthelyi, Nóra Bunford, Zoltán Vidnyánszky
UNLABELLED: Understanding atypicalities in ADHD brain correlates is a step towards better understanding ADHD etiology. Efforts to map atypicalities at the level of brain structure have been hindered by the absence of normative reference standards. Recent publication of brain charts allows for assessment of individual variation relative to age- and sex-adjusted reference standards and thus estimation not only of case-control differences but also of intraindividual prediction. METHODS: Aim was to examine, whether brain charts can be applied in a sample of adolescents (N = 140, 38% female) to determine whether atypical brain subcortical and total volumes are associated with ADHD at-risk status and severity of parent-rated symptoms, accounting for self-rated anxiety and depression, and parent-rated oppositional defiant disorder (ODD) as well as motion...
March 14, 2024: Research on child and adolescent psychopathology
https://read.qxmd.com/read/38481827/knowledge-of-parents-working-in-healthcare-settings-toward-attention-deficit-hyperactivity-disorder-among-children
#6
JOURNAL ARTICLE
Sawsan Abuhammad, Manar ALAzzam, Yasmine Alabbasi
AIM: To examine the knowledge of parents who are working as healthcare workers about Attention-Deficit Hyperactivity Disorder (ADHD) and to determine the predictors of ADHD knowledge in children among parents. METHODS: A cross-section study was conducted among parents who are working as HCWs. An online survey by google forms facilitated the creation of a 373 participant's sample. RESULTS: The parents who are working as HCWs toward ADHD Knowledge 14...
2024: Journal of Multidisciplinary Healthcare
https://read.qxmd.com/read/38425291/racial-ethnic-disparities-in-psychiatric-traits-and-diagnoses-within-a-community-based-sample-of-children-and-youth
#7
JOURNAL ARTICLE
Andrew Dissanayake, Annie Dupuis, Christie L Burton, Noam Soreni, Paul Peters, Amy Gajaria, Paul D Arnold, Russell Schachar, Jennifer Crosbie
OBJECTIVE: Racial/ethnic disparities in the prevalence of psychiatric disorders have been reported, but have not accounted for the prevalence of the traits that underlie these disorders. Examining rates of diagnoses in relation to traits may yield a clearer understanding of the degree to which racial/ethnic minority youth in Canada differ in their access to care. We sought to examine differences in self/parent-reported rates of diagnoses for obsessive-compulsive disorder (OCD), attention-deficit/hyperactivity disorder (ADHD) and anxiety disorders after adjusting for differences in trait levels between youth from three racial/ethnic groups: White, South Asian and East Asian...
March 1, 2024: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://read.qxmd.com/read/38418845/epigenome-wide-association-study-identifies-neonatal-dna-methylation-associated-with-two-year-attention-problems-in-children-born-very-preterm
#8
JOURNAL ARTICLE
Marie Camerota, Barry M Lester, Francisco Xavier Castellanos, Brian S Carter, Jennifer Check, Jennifer Helderman, Julie A Hofheimer, Elisabeth C McGowan, Charles R Neal, Steven L Pastyrnak, Lynne M Smith, Thomas Michael O'Shea, Carmen J Marsit, Todd M Everson
Prior research has identified epigenetic predictors of attention problems in school-aged children but has not yet investigated these in young children, or children at elevated risk of attention problems due to preterm birth. The current study evaluated epigenome-wide associations between neonatal DNA methylation and attention problems at age 2 years in children born very preterm. Participants included 441 children from the Neonatal Neurobehavior and Outcomes in Very Preterm Infants (NOVI) Study, a multi-site study of infants born < 30 weeks gestational age...
February 28, 2024: Translational Psychiatry
https://read.qxmd.com/read/38306154/longitudinal-patterns-of-community-based-treatment-utilization-among-ethnically-and-racially-diverse-adolescents-with-attention-deficit-hyperactivity-disorder
#9
JOURNAL ARTICLE
Devin M Hill, Margaret H Sibley, Mark A Stein, Xenia Leviyah
Background: Attention-deficit/hyperactivity disorder (ADHD) treatment utilization among adolescents is highly variable. This article describes pharmacological and nonpharmacological treatment utilization in a community sample of primarily Latinx and/or Black adolescents with ADHD ( N  = 218), followed longitudinally for 4 years, from early adolescence until approximately age 17 ( M  = 16.80, standard deviation = 1.65). Methods: Electronic surveys administered between 2012 and 2019 queried parent and youth reports of medication initiation, persistence, diversion, and misuse, as well as reasons for desistence...
February 2, 2024: Journal of Child and Adolescent Psychopharmacology
https://read.qxmd.com/read/38279814/-pills-don-t-teach-skills-adhd-coaching-identity-work-and-the-push-toward-the-liminal-medicalization-of-adhd
#10
JOURNAL ARTICLE
Meredith Bergey
Despite physicians' near monopoly over medicalization historically, various stakeholder groups shape an increasingly complex process today. This study examines a relatively new initiative, "health coaching," within the context of the changing nature of medicalization. Utilizing 51 in-depth interviews with attention deficit hyperactivity disorder (ADHD) coaches, participant observation from seven ADHD symposia, and ADHD coach publications, I examine coaching's emergence as a partial challenge to medicalization...
January 27, 2024: Journal of Health and Social Behavior
https://read.qxmd.com/read/38236104/prevalence-of-left-right-confusion-among-medical-students-in-mutah-university-jordan
#11
JOURNAL ARTICLE
Sh Mansour, N Mwafi, N Al-Tawarah, B Masoud, H Abu-Tapanjeh, I Alkhawaldeh, M Qawaqzeh, R Amro, S Mazahreh
The ability to distinguish left from right has been shown to vary substantially within healthy individuals, yet its characteristics and mechanisms are poorly understood.The study was designed in an effort to spot the extents of left-right confusion (LRC) among medical students in Mutah university and to investigate the relationship between LRC and multiple health and socioeconomic variables.Analytic cross section study was performed. Database gathered by google sheet in order to introduce them to software (starting form 12th - October / 2021 ended in 15/1/2022)...
November 2023: Georgian Medical News
https://read.qxmd.com/read/38227922/primary-prevention-of-prescription-stimulant-misuse-in-first-year-college-students
#12
JOURNAL ARTICLE
Kevin M Antshel, Aesoon Park, Stephen Maisto, Stephen V Faraone
Objective: Eight percent of college students report past year prescription stimulant misuse (nonmedical use of stimulants defined as taking stimulants in a manner other than prescribed). Despite this high prevalence rate, primary prevention efforts are lacking on college campuses. Participants and Methods: A prescription stimulant misuse primary prevention intervention targeting first-year college students was developed, refined, and pilot tested. Existing substance use treatment (motivational interviewing) and time management (cognitive behavioral therapy for adult ADHD) techniques were integrated into the novel brief prevention intervention...
January 16, 2024: Journal of American College Health: J of ACH
https://read.qxmd.com/read/38176290/the-impact-for-dcd-usa-study-the-current-state-of-developmental-coordination-disorder-dcd-in-the-united-states-of-america
#13
JOURNAL ARTICLE
Priscila Tamplain, Haylie L Miller, Derrick Peavy, Sharon Cermak, Jacqueline Williams, Melissa Licari
BACKGROUND: Developmental Coordination Disorder (DCD) is among the most under-recognized and under-supported disorders worldwide. AIMS: To present a preliminary national study that evaluated the unmet needs of children with DCD in the USA using the Impact for DCD survey. METHODS AND PROCEDURES: 232 parents of individuals aged 5-18 years provided responses from 36 items in five domains (diagnosis, activity/participation, education, therapy, and social/emotional health)...
January 3, 2024: Research in Developmental Disabilities
https://read.qxmd.com/read/38166458/genetic-association-of-lipids-and-lipid-lowering-drug-target-genes-with-attention-deficit-hyperactivity-disorder
#14
JOURNAL ARTICLE
Detong Guo, Wenchao Sheng, Yingzi Cai, Jianbo Shu, Chunquan Cai
BACKGROUND: Lipid metabolism plays an essential role in nervous system development. Cholesterol deficiency leads to a variety of neurodevelopmental disorders, such as autism spectrum disorder and fragile X syndrome. There have been a lot of efforts to search for biological markers associated with and causal to ADHD, among which lipid is one possible etiological factor that is quite widely studied. We aimed to evaluate the causal relationship between lipids traits, lipid-lowering drugs, and attention deficit hyperactivity disorder (ADHD) outcomes using Mendelian randomization (MR) studies...
January 3, 2024: Journal of Attention Disorders
https://read.qxmd.com/read/38083219/investigating-the-impact-of-control-modes-to-competency-and-engagement-in-serious-game-play-for-children-with-adhd
#15
JOURNAL ARTICLE
Jeong-Heon Song, Mahmood Jasim, Dawn Roberts, Seon-Chil Kim, Byeongil Kim, Gabriela Marie Rodriguez, Melissa Kay Hord, Hee-Tae Jung
Serious games are designed to reduce symptoms of attention deficit among children with Attention Deficit/Hyperactivity Disorder (ADHD). These games predominantly use touchscreen interfaces that children with ADHD play in a sitting position, which contributes to already-problematic sedentary behaviors. In an effort to mitigate negative impacts of sedentary behavior, we set out to investigate the use of Dance Dance Revolution (DDR) mats with serious games to induce gross movements. To that end, we designed and implemented Breathtaking Glass Bridge to investigate the impact of interface (DDR vs...
July 2023: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://read.qxmd.com/read/38082795/toward-digital-phenotypes-of-early-childhood-mental-health-via-unsupervised-and-supervised-machine-learning
#16
JOURNAL ARTICLE
Bryn C Loftness, Donna M Rizzo, Julia Halvorson-Phelan, Aisling O'Leary, Shania Prytherch, Carter Bradshaw, Anna Jane Brown, Nick Cheney, Ellen W McGinnis, Ryan S McGinnis
Childhood mental health disorders such as anxiety, depression, and ADHD are commonly-occurring and often go undetected into adolescence or adulthood. This can lead to detrimental impacts on long-term wellbeing and quality of life. Current parent-report assessments for pre-school aged children are often biased, and thus increase the need for objective mental health screening tools. Leveraging digital tools to identify the behavioral signature of childhood mental disorders may enable increased intervention at the time with the highest chance of long-term impact...
July 2023: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://read.qxmd.com/read/38079098/prevalence-of-undiagnosed-attention-deficit-hyperactivity-disorder-adhd-symptoms-in-the-young-adult-population-of-the-united-arab-emirates-a-national-cross-sectional-study
#17
JOURNAL ARTICLE
Nabeel Al-Yateem, Shameran Slewa-Younan, Aram Halimi, Sara Aideed Saeed, Daniah Tliti, Muna Mohammad, Mada Ridwan, Razan Zeidan, Muna Hasan Hammash, Fatma Refaat Ahmed, Jacqueline Maria Dias, Syed Azizur Rahman, Muhammad Arsyad Subu, Heba Hijazi, Fatemeh Yeganeh, Aaliyah Momani, Mitra Zandi, Richard Mottershead
BACKGROUND: Attention deficit hyperactivity disorder (ADHD), a globally prevalent behavioural disorder, remains underdiagnosed, particularly among adults. This issue is exacerbated in the Arab region due to stigma and insufficient healthcare facilities and professionals. Despite the United Arab Emirates (UAE) efforts to improve mental healthcare, shortcomings persist. No studies in the UAE currently assesses the appropriateness of the screening system for ADHD and other behavioural issues...
December 11, 2023: Journal of Epidemiology and Global Health
https://read.qxmd.com/read/38054660/adhd-and-the-avoidance-of-mental-effort-the-role-of-response-inhibition-and-avoidance-motivation
#18
JOURNAL ARTICLE
Ibrahim Orhan, Philip J Corr, Dino Krupić
OBJECTIVE: The tendency of people with ADHD to avoid tasks that require mental effort impacts their academic achievement. Findings in the literature suggest that children with ADHD find cognitive tasks more effortful and uncomfortable than their typically developing peers. However, neuropsychological processes contributing to this remain unclear. The present study investigated whether the relationship between prepotent motor response inhibition and avoiding mental effort is mediated by the ability to resist avoidance motivation and whether this proposed mediation mechanism is contingent on ADHD diagnosis...
December 6, 2023: Journal of Clinical and Experimental Neuropsychology
https://read.qxmd.com/read/38008786/social-and-monetary-reward-processing-in-youth-with-early-emerging-personality-pathology-an-rdoc-informed-study
#19
JOURNAL ARTICLE
Dara E Babinski, Autumn Kujawa, Samantha Pegg, Julia M Leslie, Cameron Pothoven, Daniel A Waschbusch, Carla Sharp
Very little is known about the mechanisms underlying the development of personality disorders, hindering efforts to address early risk for these costly and stigmatized disorders. In this study, we examined associations between social and monetary reward processing, measured at the neurophysiological level, and personality pathology, operationalized through the Level of Personality Functioning (LPF), in a sample of early adolescent females (Mage  = 12.21 years old, SD = 1.21)...
November 27, 2023: Research on child and adolescent psychopathology
https://read.qxmd.com/read/37971947/coping-with-emotional-dysregulation-among-young-adults-with-adhd-a-mixed-method-study-of-self-awareness-and-strategies-in-daily-life
#20
JOURNAL ARTICLE
Maayan Ben-Dor Cohen, Mor Nahum, Ruthie Traub Bar-Ilan, Eran Eldar, Adina Maeir
BACKGROUND: Emotional dysregulation (ED) impacts functional outcomes among individuals with attention-deficit hyperactivity disorder (ADHD). Self-awareness and strategies may enhance coping with ED yet are rarely studied in ADHD. OBJECTIVES: To explore ED-related self-awareness and strategies in daily life of adults with ADHD, and to examine the interrelations between them and their association with symptoms. METHODS: Sixty young adults with ADHD participated in a mixed-method study...
November 16, 2023: Neuropsychological Rehabilitation
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