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https://www.readbyqxmd.com/read/28181385/hemodynamic-profile-and-behavioral-characteristics-during-induction-of-anesthesia-in-pediatric-patients-with-attention-deficit-hyperactivity-disorder
#1
Richard S Cartabuke, Joseph D Tobias, Julie Rice, Dmitry Tumin
AIM: There is no consensus regarding the administration of stimulant drugs preoperatively, particularly in pediatric patients diagnosed with ADHD. The primary objective of the current study was to assess differences in blood pressure and heart rate before and after induction of anesthesia between patients on chronic amphetamine or methylphenidate therapy who receive their normal dose preoperatively compared to patients in whom the prescribed medication was withheld. Secondary objectives were to assess the anxiety level during the induction of anesthesia and the effect of premedication with midazolam...
February 8, 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28181060/parents-and-children-s-adhd-in-a-family-system
#2
EDITORIAL
Kirby Deater-Deckard
ADHD symptoms "run in families". However, relatively little is known about the ways in which parents' symptoms might additively and interactively work with the parenting environment, to influence (and be influenced by) the developmental trajectory of symptoms in children and adolescents. In this commentary on the special section addressing this gap in knowledge, emphasis is placed on the importance of replicating and extending family-wide studies of ADHD symptoms and etiology. The current papers exemplify the leading-edge of such efforts, demonstrating the feasibility and rigor with which studies are being conducted, utilizing longitudinal and experimental designs...
February 8, 2017: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/28154545/influence-of-the-slc6a3-dat1-gene-on-multifaceted-measures-of-self-regulation-in-preschool-children
#3
Lina M Cómbita, Pascale Voelker, Alicia Abundis-Gutiérrez, Joan P Pozuelos, M Rosario Rueda
Development of self-regulation, the capacity to voluntarily modulate thoughts, emotions and actions is strongly related to the maturation of the dopamine-mediated executive attention network (EAN). The attention control processes associated with the EAN greatly overlap with efficiency of the executive functions and are correlated with measures of effortful control. Regulation of dopamine levels within the EAN, particularly in the basal ganglia is carried out by the action of dopamine transporters. In humans, the SLC6A3/DAT1 gene carries out the synthesis of the DAT protein...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28141724/inattentive-attention-deficit-hyperactivity-disorder-stimulant-medication-and-weight-loss-in-a-15-year-old-girl-are-we-enabling-the-development-of-an-eating-disorder
#4
Sai Iyer, Maya Kumar, Michael I Reiff, Martin T Stein
Nicole is a 15-year-old girl presenting to the Developmental Behavioral Pediatrics Clinic with symptoms of the inattentive type of Attention-Deficit/Hyperactivity Disorder (ADHD) and declining school performance over the last year. She expressed frustration over her inability to concentrate on schoolwork. Assuming that her poor grades were secondary to lack of effort, her parents withdrew privileges. Nicole became increasingly depressed. She stopped participating in activities, she previously enjoyed, and her parents reported that she stopped singing in the shower...
February 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28103159/the-effects-of-stimulant-medication-and-training-on-sports-competence-among-children-with-adhd
#5
Amy R Altszuler, Anne S Morrow, Brittany M Merrill, Shannon Bressler, Fiona L Macphee, Elizabeth M Gnagy, Andrew R Greiner, Stefany Coxe, Joseph S Raiker, Erika Coles, William E Pelham
The current study examined the relative efficacy of behavioral sports training, medication, and their combination in improving sports competence among youth with attention deficit/hyperactivity disorder (ADHD). Participants were 73 youth (74% male; 81% Hispanic) between the ages of 5 and 12 diagnosed with Diagnostic and Statistical Manual of Mental Disorders (4th ed.) ADHD enrolled in a Summer Treatment Program (STP). The study consisted of a 2 (medication: methylphenidate, placebo) × 2 (sports training: instruction and practice, recreational play) between-groups design and was conducted over a 3-week period during the STP...
January 19, 2017: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/28073033/situating-violent-ideations-within-the-landscape-of-mental-health-associations-between-violent-ideations-and-dimensions-of-mental-health
#6
Aja Louise Murray, Manuel Eisner, Ingrid Obsuth, Denis Ribeaud
Violent ideations occur more frequently in individuals with mental health problems. They may be of interest in clinical contexts as possible indicators of dangerousness, as corollaries of mental health problems, as candidate treatment targets and as potentially playing a role in perpetuation or onset of symptoms. In spite of their relevance to mental health, some fundamental questions about their place within the broader landscape of mental health problems remain unanswered. To provide a basic characterisation of the relations between violent ideations and dimensions of mental health and provide a foundation for future research in this area we factor analysed a measure of violent ideations and an omnibus measure of mental health dimensions in a normative sample of 1306 youth (at age 17)...
January 3, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28000020/structural-brain-imaging-correlates-of-asd-and-adhd-across-the-lifespan-a-hypothesis-generating-review-on-developmental-asd-adhd-subtypes
#7
REVIEW
Nanda Rommelse, Jan K Buitelaar, Catharina A Hartman
We hypothesize that it is plausible that biologically distinct developmental ASD-ADHD subtypes are present, each characterized by a distinct time of onset of symptoms, progression and combination of symptoms. The aim of the present narrative review was to explore if structural brain imaging studies may shed light on key brain areas that are linked to both ASD and ADHD symptoms and undergo significant changes during development. These findings may possibly pinpoint to brain mechanisms underlying differential developmental ASD-ADHD subtypes...
February 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/27987253/treatment-and-risk-factors-of-internet-use-disorders
#8
REVIEW
Hideki Nakayama, Satoko Mihara, Susumu Higuchi
Recently many young people have developed internet use disorders (IUDs) as a result of the proliferation of internet enabled devices, leading to serious health and social problems worldwide. On occasion, medical and educational institutions, governments and other groups, have sought to take preventive action or treat IUDs. In many cases, the preferred treatment for IUDs is to set recommendations for appropriate internet use. Reportedly, psychosocial therapies (including CBT, family therapy, compound therapy) for IUDs and pharmacotherapies (including antidepressant drugs and psychostimulants) for co-morbid psychiatric or development disorders have been effective at reducing the degree and symptoms of IUDs...
December 17, 2016: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/27866153/exploring-personality-and-readiness-to-change-in-patients-with-substance-use-disorders-with-and-without-adhd
#9
L Flores-García, E Ytterstad, M B Lensing, M Eisemann
OBJECTIVE: To explore personality and readiness to change among substance use disorders (SUD) patients with and without ADHD. METHOD: SUD + ADHD versus SUD - ADHD patients consecutively entering treatment between 2010 and 2012 were compared concerning personality (Temperament and Character Inventory) and readiness to change (Stages of Change Readiness and Treatment Eagerness Scale). RESULTS: Among 103 SUD patients (76 men, age M = 43.3, SD = 11...
November 19, 2016: Journal of Attention Disorders
https://www.readbyqxmd.com/read/27834440/role-of-school-teachers-in-identifying-attention-deficit-hyperactivity-disorder-among-primary-school-children-in-mansoura-egypt
#10
N J Awadalla, O F Ali, S Elshaer, M Eissa
There is a knowledge gap in primary school teachers that affects their ability to detect attention deficit hyperactivity disorder (ADHD). This study measured primary school teachers' knowledge about ADHD, and implemented a training programme to improve early detection of ADHD. The prevalence and risk factors of ADHD were also studied. The training programme was implemented through a 2-day workshop for 39 primary school teachers who completed a validated Arabic version of the ADHD Rating Scale for 873 primary school children...
November 2, 2016: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/27809572/identification-of-two-heritable-cross-disorder-endophenotypes-for-tourette-syndrome
#11
Sabrina M Darrow, Matthew E Hirschtritt, Lea K Davis, Cornelia Illmann, Lisa Osiecki, Marco Grados, Paul Sandor, Yves Dion, Robert King, David Pauls, Cathy L Budman, Danielle C Cath, Erica Greenberg, Gholson J Lyon, Dongmei Yu, Lauren M McGrath, William M McMahon, Paul C Lee, Kevin L Delucchi, Jeremiah M Scharf, Carol A Mathews
OBJECTIVE: Phenotypic heterogeneity in Tourette syndrome is partly due to complex genetic relationships among Tourette syndrome, obsessive-compulsive disorder (OCD), and attention deficit hyperactivity disorder (ADHD). Identifying symptom-based endophenotypes across diagnoses may aid gene-finding efforts. METHOD: Assessments for Tourette syndrome, OCD, and ADHD symptoms were conducted in a discovery sample of 3,494 individuals recruited for genetic studies. Symptom-level factor and latent class analyses were conducted in Tourette syndrome families and replicated in an independent sample of 882 individuals...
November 4, 2016: American Journal of Psychiatry
https://www.readbyqxmd.com/read/27713929/intrinsic-functional-connectivity-in-attention-deficit-hyperactivity-disorder-a-science-in-development
#12
F Xavier Castellanos, Yuta Aoki
Functional magnetic resonance imaging (fMRI) without an explicit task, i.e., resting state fMRI, of individuals with Attention-Deficit/Hyperactivity Disorder (ADHD) is growing rapidly. Early studies were unaware of the vulnerability of this method to even minor degrees of head motion, a major concern in the field. Recent efforts are implementing various strategies to address this source of artifact along with a growing set of analytical tools. Availability of the ADHD-200 Consortium dataset, a large-scale multi-site repository, is facilitating increasingly sophisticated approaches...
May 2016: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/27612082/identification-of-adhd-in-youth-with-epilepsy
#13
Mary C Kral, Michelle D Lally, Andrea D Boan
PURPOSE: To further characterize Attention-Deficit/Hyperactivity Disorder (ADHD) in a clinic-referred sample of youth with epilepsy. METHODS: Children and adolescents with epilepsy who were referred for comprehensive neuropsychological evaluation comprised the sample. Data were obtained via archival record review. Youth with epilepsy were grouped according to ADHD diagnosis (no ADHD, ADHD - Combined Type, and ADHD - Predominantly Inattentive Type) and compared for a number of neurocognitive variables, seizure-related variables, and parent and teacher completed behavior rating scale variables...
September 2, 2016: Journal of Pediatric Rehabilitation Medicine
https://www.readbyqxmd.com/read/27601976/ts-eurotrain-a-european-wide-investigation-and-training-network-on-the-etiology-and-pathophysiology-of-gilles-de-la-tourette-syndrome
#14
Natalie J Forde, Ahmad S Kanaan, Joanna Widomska, Shanmukha S Padmanabhuni, Ester Nespoli, John Alexander, Juan I Rodriguez Arranz, Siyan Fan, Rayan Houssari, Muhammad S Nawaz, Francesca Rizzo, Luca Pagliaroli, Nuno R Zilhäo, Tamas Aranyi, Csaba Barta, Tobias M Boeckers, Dorret I Boomsma, Wim R Buisman, Jan K Buitelaar, Danielle Cath, Andrea Dietrich, Nicole Driessen, Petros Drineas, Michelle Dunlap, Sarah Gerasch, Jeffrey Glennon, Bastian Hengerer, Odile A van den Heuvel, Cathrine Jespersgaard, Harald E Möller, Kirsten R Müller-Vahl, Thaïra J C Openneer, Geert Poelmans, Petra J W Pouwels, Jeremiah M Scharf, Hreinn Stefansson, Zeynep Tümer, Dick J Veltman, Ysbrand D van der Werf, Pieter J Hoekstra, Andrea Ludolph, Peristera Paschou
Gilles de la Tourette Syndrome (GTS) is characterized by the presence of multiple motor and phonic tics with a fluctuating course of intensity, frequency, and severity. Up to 90% of patients with GTS present with comorbid conditions, most commonly attention-deficit/hyperactivity disorder (ADHD), and obsessive-compulsive disorder (OCD), thus providing an excellent model for the exploration of shared etiology across disorders. TS-EUROTRAIN (FP7-PEOPLE-2012-ITN, Grant Agr.No. 316978) is a Marie Curie Initial Training Network (http://ts-eurotrain...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27503948/integrity-of-amygdala-subregion-based-functional-networks-and-emotional-lability-in-drug-na%C3%A3-ve-boys-with-adhd
#15
Xiaoyan Yu, Lu Liu, Wai Chen, Qingjiu Cao, Florian Daniel Zepf, Gongjun Ji, Zhaomin Wu, Li An, Peng Wang, Qiujin Qian, Yufeng Zang, Li Sun, Yufeng Wang
OBJECTIVE: This study evaluated the functional networks of amygdala subregions (basolateral [BLA], centromedial [CMA], and superficial amygdala [SFA]) in ADHD and their association with emotional lability (EL) symptoms. METHOD: Resting-state functional connectivity (RSFC) of amygdala subregions and their correlations with EL scores were evaluated in 35 drug-naïve boys with ADHD and 30 age-matched healthy controls (HC). RESULTS: Compared with HC, altered RSFC were detected differently for each amygdala subregion in ADHD: altered RSFC of BLA with the thalamus and vermis; aberrant RSFC of CMA with the superior temporal gyrus/pole and insula, precuneus and cerebellum; reduced RSFC of SFA with dorsal frontoparietal cortices...
August 8, 2016: Journal of Attention Disorders
https://www.readbyqxmd.com/read/27494646/motives-underlying-smoking-in-college-students-with-adhd
#16
Kerrie Glass Murphy, Kate Flory
BACKGROUND: The positive association between attention deficit hyperactivity disorder (ADHD) symptoms and smoking in youth has been well documented. Less research has examined why individuals with ADHD, particularly college students, are at increased risk for smoking. OBJECTIVES: This longitudinal study examined whether smoking motives [cognitive enhancement, tolerance, negative reinforcement (smoking to reduce negative affect or stress), craving, social influences, and weight control] helped to explain the relation between ADHD symptoms (inattention and hyperactivity/impulsivity) and cigarette smoking among college students...
August 5, 2016: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27467139/safety-and-efficacy-considerations-due-to-misuse-of-extended-release-formulations-of-stimulant-medications
#17
REVIEW
Rakesh Jain, Jeffrey G Stark
Amphetamine or methylphenidate are first-line options for treating attention-deficit/hyperactivity disorder (ADHD). Deviations from suggested routes of administration such as crushing, chewing, intravenous administration, or snorting stimulant medication may alter the release rate, absorption, and bioavailability of the active drug. Additionally, the pharmacokinetic (PK) profiles of extended-release formulations of certain medications (e.g., some opioids) are known to be dangerously altered when consumed with alcohol; specifically, there is an unintended, rapid release of a significant portion of the drug (dose dumping)...
September 2016: Postgraduate Medicine
https://www.readbyqxmd.com/read/27448275/erp-correlates-of-proactive-and-reactive-cognitive-control-in-treatment-na%C3%A3-ve-adult-adhd
#18
Venke Arntsberg Grane, Jan Ferenc Brunner, Tor Endestad, Ida Emilia S Aasen, Juri Kropotov, Robert Thomas Knight, Anne-Kristin Solbakk
This study investigated whether treatment naïve adults with Attention Deficit Hyperactivity Disorder (ADHD; n = 33; 19 female) differed from healthy controls (n = 31; 17 female) in behavioral performance, event-related potential (ERP) indices of preparatory attention (CueP3 and late CNV), and reactive response control (Go P3, NoGo N2, and NoGo P3) derived from a visual cued Go/NoGo task. On several critical measures, Cue P3, late CNV, and NoGo N2, there were no significant differences between the groups. This indicated normal preparatory processes and conflict monitoring in ADHD patients...
2016: PloS One
https://www.readbyqxmd.com/read/27429094/post-error-adjustments-and-adhd-symptoms-in-adults-the-effect-of-laterality-and-state-regulation
#19
Saleh M H Mohamed, Norbert A Börger, Reint H Geuze, Jaap J van der Meere
Evidence is accumulating that individuals with Attention-Deficit/Hyperactivity Disorder (ADHD) do not adjust their responses after committing errors. Post-error response adjustments are taken to reflect, among others, error monitoring that is essential for learning, flexible behavioural adaptation, and achieving future goals. Many behavioural studies have suggested that atypical lateral brain functions and difficulties in allocating effort to protect performance against stressors (i.e., state regulation) are key factors in ADHD...
October 2016: Brain and Cognition
https://www.readbyqxmd.com/read/27329487/effort-allocation-in-children-with-adhd-abnormal-decision-making-or-poor-execution
#20
Yael Winter, Hilla Ben-Pazi, Yehuda Pollak
OBJECTIVE: Effort allocation is a multi-faceted process driving both the decision to choose a high effort-high reward alternative over a low effort-low reward alternative, and the execution of this decision by recruiting sufficient effort. The objectives of our study were to examine whether children with ADHD would (a) show different reward-effort cost trade-off, and (b) have difficulty executing their decision. METHOD: 50 children, aged 9 to 15, with and without ADHD, had to choose between high effort-high reward and low effort-low reward alternatives using a handheld dynamometer and to execute their choice...
June 20, 2016: Journal of Attention Disorders
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