Sulieman Ibraheem Shelash Al-Hawary, Saade Abdalkareem Jasim, Mustafa M Kadhim, Sarah Jaafar Saadoon, Irfan Ahmad, Rosario Mireya Romero Parra, Suzan Hasan Hammoodi, Roua Abulkassim, Noora M Hameed, Waleed K Alkhafaje, Yasser Fakri Mustafa, Mohammad Javed Ansari
Liver cancer is the sixth most prevalent cancer and ranks third in cancer-related death, after lung and colorectal cancer. Various natural products have been discovered as alternatives to conventional cancer therapy strategies, including radiotherapy, chemotherapy, and surgery. Curcumin (CUR) with antiinflammatory, antioxidant, and antitumor activities has been associated with therapeutic benefits against various cancers. It can regulate multiple signaling pathways, such as PI3K/Akt, Wnt/β-catenin, JAK/STAT, p53, MAPKs, and NF-ĸB, which are involved in cancer cell proliferation, metastasis, apoptosis, angiogenesis, and autophagy...
March 8, 2023: Phytotherapy Research: PTR