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Marcus Vinicius Rozo Rodrigues, Valdir Tercioti-Junior, Luiz Roberto Lopes, João de Souza Coelho-Neto, Nelson Adami Andreollo
BACKGROUND: Breast cancer is the most common malignant neoplasm in the female population. However, stomach is a rare site for metastasis, and can show up many years after initial diagnosis and treatment of the primary tumor. AIM: Analyze a case series of this tumor and propose measures that can diagnose it with more precocity. METHODS: Were analyzed 12 patients with secondary gastric tumors. Immunohistochemistry has demonstrated that primary tumor was breast cancer...
April 2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
Cristina Botelho Barra, Ivani Novato Silva, Isabela Leite Pezzuti, José Nélio Januário
OBJECTIVE: The effectiveness of neonatal screening for reducing morbimortality in children with congenital adrenal hyperplasia (CAH) is the main justification for its implementation. One of the challenges for its implementation is to determine the cutoff value for laboratory measurement of 17-hydroxyprogesterone (17OHP) with appropriate cost-effectiveness. This study identified factors affecting the results of the pilot project of newborn screening for CAH, performed in the state of Minas Gerais, Brazil...
July 2012: Revista da Associação Médica Brasileira
H Rassi, M Houshmand, M Hashemi, K Majidzadeh, M H Hosseini Akbari, M Shafa Shariat Panahi
Breast cancer is the most common malignancy among females in the world. Age and familial history are the major risk factors for the development of this disease in Iran. Mutations of BRCA1 and BRCA2 genes are associated with a greatly increased risk for development of familial breast cancer. Frequency of BRCA mutations was identified in familial breast cancers (FBC) and non-familial breast cancers (NFBC) by molecular genetics, morphological and Immunohistochemical methods. Thirty forth formalin-fixed, paraffin-embedded breast tissue tumors were analyzed from 16 patients with FBC and 18 patients with NFBC...
March 2008: T︠S︡itologii︠a︡ i Genetika
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