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https://www.readbyqxmd.com/read/28922303/perioperative-outcomes-complications-and-efficacy-of-robotic-assisted-prolapse-repair-a-single-institution-study-of-196-patients
#1
Priyanka Gupta, Michael Ehlert, Jamie Bartley, Jason Gilleran, Kim A Killinger, Judith A Boura, Pradeep Nagaraju, Melissa Fischer
Abdominal pelvic organ prolapse repair is efficacious for uterovaginal and apical prolapse. We describe the safety and efficacy of robotic prolapse repair in a large teaching institution. METHODS: Consecutive robotic-assisted prolapse repairs at a single institution between 2006 and 2014 were retrospectively reviewed for patient characteristics, operative information, and outcomes. RESULTS: A total of 196 women (mean age, 61 ± 9 years) underwent robotic prolapse repair (189 sacrocolpopexy, 6 sacrohysteropexy, 1 enterocele repair)...
September 15, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28903451/the-correlation-of-sperm-morphology-with-unexplained-recurrent-spontaneous-abortion-a-systematic-review-and-meta-analysis
#2
REVIEW
Xiaodan Cao, Yun Cui, Xiaoxia Zhang, Jiangtao Lou, Jun Zhou, Renxiong Wei
Sperm morphology displays a potential impact on sperm function and may ultimately impact reproductive function. Current studies have investigated the correlation between sperm morphology with unexplained recurrent spontaneous abortion (RSA) but have shown inconsistent results. Hence, we systematically searched MEDLINE, EMBASE, CNKI databases, as well as the Cochrane Library for studies that examined the association between sperm morphology and unexplained RSA. Fifteen studies were identified, including 883 cases and 530 controls...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28902929/women-with-recurrent-spontaneous-abortion-have-decreased-25-oh-vitamin-d-and-vdr-at-the-fetal-maternal-interface
#3
N Li, H M Wu, F Hang, Y S Zhang, M J Li
Immunological mechanisms have been proposed to underlie the pathogenesis of recurrent spontaneous abortion (RSA). Vitamin D has a potent immunomodulatory effect, which may affect pregnancy outcome. The objective of this study was to investigate 25-hydroxyvitamin D [25(OH) D] concentration and vitamin D receptor (VDR) expression in the decidual tissues of RSA patients. Thirty women with RSA (RSA group) and thirty women undergoing elective abortion (control group) were recruited during 2016 from gynecology outpatient clinics...
September 12, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/28888228/transperineal-cryotherapy-for-unresectable-muscle-invasive-bladder-cancer-preliminary-experience-with-7-male-patients
#4
Qing Zhang, Shiwei Zhang, Shun Zhang, Wei Wang, Xiaozhi Zhao, Yongming Deng, Huibo Lian, Hongqian Guo
BACKGROUND: Radical cystectomy (RC) with pelvic lymph node dissection (PLND) and urinary diversion (UD) is considered the standard treatment for muscle invasive bladder cancer (MIBC). In a part of patients, RC procedure is aborted due to unresectable disease, other followed treatment like systemic chemotherapy, radiotherapy or cryotherapy may be a better option. The aim of present study was to report the preliminary results of transperineal cryotherapy for unresectable muscle invasive bladder cancer...
September 9, 2017: BMC Urology
https://www.readbyqxmd.com/read/28877731/hypoluteoidism-in-a-dog-associated-with-recurrent-mammary-fibroadenoma-stimulated-by-progestin-therapy
#5
Maria Teresa Zedda, Luisa Bogliolo, Elisabetta Antuofermo, Laura Falchi, Federica Ariu, Giovanni Pietro Burrai, Salvatore Pau
BACKGROUND: Hypoluteoidism in the bitch is characterized by insufficient production and secretion of progesterone by the corpora lutea. It is a rare pathologic condition and during pregnancy, it leads to embryonic resorption or fetal abortion. Supplementary therapy with progestins is indicated during pregnancy to obtain delivery of vital puppies but unwarranted side effects of such treatment are poorly documented. CASE PRESENTATION: A 4-year-old, nulliparous, female Istrian Shorthaired Hound dog had been mated repeatedly in six heats with different dogs of proven fertility but signs of pregnancy did not develop...
September 6, 2017: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/28867860/ayurvedic-management-of-recurrent-abortions-due-to-uterine-fibroid
#6
Shailendra Dadarao Katakdound
Uterine fibroids are present in 30-70% of women of reproductive age. Uterine fibroids distort the uterine cavity. Therefore there is consensus of a negative impact on both the clinical pregnancy and delivery rates.[2] In addition, studies have also reported an increased risk of spontaneous miscarriage with submucosal fibroids. In biomedicine, myomectomy is considered the treatment of choice and Assisted Reproductive Technology is advised to overcome infertility. In Hārita Saṃhitā treatment is given for recurrent abortion (Garbhasrāvī)...
January 2017: Ancient Science of Life
https://www.readbyqxmd.com/read/28865602/placental-apoptosis-in-recurrent-miscarriage
#7
Tarek A Atia
Apoptosis is an interactive and dynamic biological process involved in all phases of embryogenesis. We aimed to study the effect of placental apoptosis on recurrent miscarriage (RM). Placental tissue samples were collected from 40 women with RM (study group) and 30 women with sporadic spontaneous abortion (control group). Samples were prepared and stained immunohistochemically with markers for both the apoptotic protein (p53) and anti-apoptotic Bcl-2 antibodies. Our results showed that expression of the apoptotic (p53) protein was significantly increased in the placental tissues of the RM group (p = 0...
September 2017: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/28860933/expression-level-of-tnf-%C3%AE-in-decidual-tissue-and-peripheral-blood-of-patients-with-recurrent-spontaneous-abortion
#8
Song Li, Lei Wang, Zhifang Xing, Yanping Huang, Zengmin Miao
OBJECTIVE: This study aimed to determine the express level of tumour necrosis factor α (TNF-α) in the decidual tissue and peripheral blood of patients with recurrent spontaneous abortion (RSA). MATERIAL AND METHODS: Eighty RSA patients and 100 control women were recruited in this study. Enzyme-linked immunosorbent assay (ELISA) was applied to determine the expression level of TNF-α in peripheral blood and decidual tissues from both groups. Additionally, the expression level of TNF-α was compared between RSA patients with different numbers of abortions, as well as primary and secondary RSA patients...
2017: Central-European Journal of Immunology
https://www.readbyqxmd.com/read/28838524/aborted-sudden-cardiac-death-after-unroofing-of-anomalous-left-coronary-artery
#9
Hitesh Agrawal, S Kristen Sexson-Tejtel, Athar M Qureshi, Mahboob Alam, Prakash Masand, Charles D Fraser, Silvana Molossi, Carlos M Mery
We describe a patient with anomalous left coronary artery with a short intramural course and a previously unrecognized myocardial bridge who presented with a recurrent episode of aborted sudden cardiac death. Intravascular ultrasound and fractional flow reserve showed significant compression at the left coronary artery ostium by the intercoronary pillar and at the myocardial bridge. Intravascular ultrasound and fractional flow reserve were normal after coronary translocation and unroofing of the myocardial bridge...
September 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28825764/systemic-sclerosis-exploring-the-potential-interplay-between-thyroid-disorders-and-pregnancy-outcome-in-an-italian-cohort
#10
Paola Triggianese, Paola Conigliaro, Maria Sole Chimenti, Carmen Barbato, Elisabetta Greco, Barbara Kroegler, Caterina De Carolis, Roberto Perricone
BACKGROUND: Evidence has shown that pregnancy failure (PF) in women with systemic sclerosis (SSc) consists mainly of preterm delivery (PD) and intrauterine growth restriction (IUGR). Thyroid dysfunction (TD) and Hashimoto's thyroiditis (HT) represent a common feature of SSc. Since TD has been associated with PF, its presence in SSc women may potentially affect pregnancy outcome. OBJECTIVES: To analyze the interplay between TD and PF in a cohort of SSc women. METHODS: SSc women (n=77) and age-matched controls from the general obstetric population (n=50) were included...
August 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28817820/endo-urological-techniques-for-benign-uretero-ileal-strictures-have-poor-efficacy-and-affect-renal-function
#11
Elisabeth E Fransen van de Putte, Liesbeth L de Wall, Erik van Werkhoven, Eddi A Heldeweg, Axel Bex, Henk G van der Poel, Bas W G van Rhijn, Simon Horenblas, Kees Hendricksen
INTRODUCTION: Uretero-ileal strictures (UES) following urinary diversion are therapeutically challenging. We compared the efficacy, safety and renal outcome following therapeutic endo-urological techniques (EUTs) and open surgical revision of the anastomosis (SRA) for UES. MATERIAL AND METHODS: We retrospectively analysed all EUTs and SRAs performed for UES in 2 hospitals between 1987 and 2015. Restenosis was defined as recurrent radiographically diagnosed hydronephrosis and re-intervention...
August 18, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28810565/alteration-of-th17-and-foxp3-regulatory-t-cells-in-patients-with-unexplained-recurrent-spontaneous-abortion-before-and-after-the-therapy-of-hcg-combined-with-immunoglobulin
#12
Jing Sha, Fumin Liu, Jingfang Zhai, Xiaoyun Liu, Qinglin Zhang, Bei Zhang
We conducted this study to investigate the effects of the combination therapy of human chorionic gonadotropin (hCG) plus immunoglobulin (IG) on the levels of T helper 17 (Th17) cells and Foxp3(+) regulatory T cells (Treg) in patients with unexplained recurrent spontaneous abortion (URSA). Twenty pregnant women with URSA underwent combination therapy of hCG plus IG. Flow cytometry was performed to measure the proportions of Th17 and Treg cells before and after treatment. RT-PCR and ELISA were applied to detect the concentrations of interleukin (IL)-17, IL-6, IL-10, and transforming growth factor (TGF)-β1 in the peripheral blood...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28801981/pregnancy-outcomes-in-mothers-of-offspring-with-inherited-bone-marrow-failure-syndromes
#13
Neelam Giri, Helen D Reed, Pamela Stratton, Sharon A Savage, Blanche P Alter
BACKGROUND: Children with inherited bone marrow failure syndromes (IBMFSs) may be symptomatic in utero, resulting in maternal and fetal problems during the pregnancy. Subsequent pregnancies by their mothers should be considered "high risk". METHODS: We retrospectively analyzed outcomes of 575 pregnancies in 165 unaffected mothers of offspring with Fanconi anemia (FA), dyskeratosis congenita (DC), Diamond-Blackfan anemia (DBA), and Shwachman-Diamond syndrome (SDS) for events noted during pregnancy, labor, and delivery...
August 12, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28798930/adverse-pregnancy-outcomes-of-patients-with-history-of-first-trimester-recurrent-spontaneous-abortion
#14
Jing Yang, Yan Wang, Xiao-Ye Wang, Yan-Yu Zhao, Jing Wang, Yang-Yu Zhao
Although a history of first-trimester recurrent spontaneous abortion (FRSA) is regarded as a risk factor in antenatal care, the characteristic of subsequent pregnancy outcome is not clearly elucidated. Here, a retrospective analysis was performed on the clinical data of 492 singleton pregnant women. 164 of them with the history of FRSA were enrolled in study group, compared to 328 deliveries without the history of FRSA. For maternal outcomes, patients in the study group delivered earlier with mean gestational age and the incidences of cesarean section and postpartum hemorrhage were higher compared to the control group...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28797161/masked-inherited-primary-arrhythmia-syndromes-in-sudden-cardiac-death-patients-accompanied-by-coronary-vasospasm
#15
Ki Hong Lee, Hyung Wook Park, Jeong Nam Eun, Jeong Gwan Cho, Nam Sik Yoon, Mi Ran Kim, Yo Han Ku, Hyukjin Park, Seung Hun Lee, Jeong Han Kim, Min Chul Kim, Woo Jin Kim, Hyun Kuk Kim, Jae Yeong Cho, Keun-Ho Park, Doo Sun Sim, Hyun Ju Yoon, Kye Hun Kim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn, Myung Ho Jeong, Jong Chun Park
BACKGROUND/AIMS: Coronary vasospasms are one of the important causes of sudden cardiac death (SCD). Provocation of coronary vasospasms can be useful, though some results may lead to false positives, with patients potentially experiencing recurrent SCD despite appropriate medical treatments. We hypothesized that it is not coronary vasospasms but inherited primary arrhythmia syndromes (IPAS) that underlie the development of SCD. METHODS: We analyzed 74 consecutive patients (3...
September 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28771916/vitamin-d-deficiency-in-an-italian-cohort-of-infertile-women
#16
Paola Triggianese, Abdulla Watad, Francesca Cedola, Carlo Perricone, Howard Amital, Ilio Giambini, Roberto Perricone, Yehuda Shoenfeld, Caterina De Carolis
PROBLEM: The purpose of this study was to explore whether vitamin D might be a marker of female primary infertility in association with the presence of autoimmune diseases (ADs). METHODS: The study was a cross-sectional descriptive study in consecutive outpatients of the Polymedical Center for Prevention of Recurrent Spontaneous Abortion (RSA), in Rome, Italy. Women were eligible if they received a diagnosis of primary infertility or RSA. Serum vitamin D, calcium, and PTH were analyzed...
August 3, 2017: American Journal of Reproductive Immunology: AJRI
https://www.readbyqxmd.com/read/28756129/outcomes-of-threatened-abortions-after-anticoagulation-treatment-to-prevent-recurrent-pregnancy-loss
#17
Amihai Rottenstreich, Hagai Amsalem, Geffen Kleinstern, Yosef Kalish
We aimed to determine the outcome of threatened abortion in women treated with low-molecular weight heparin (LMWH) for recurrent pregnancy loss (RPL). Data of women with RPL who experienced threatened abortion while taking LMWH between 2007 and 2016 were retrospectively reviewed. All patients received the LMWH, enoxaparin (40 mg). Thrombophilia was present in 38 (33.3%) women, including 11 (9.6%) with antiphospholipid syndrome (APLS). The overall live birth rate was 58.8% (67/114). Live birth rates were 87...
July 3, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28755426/radical-hysterectomy-after-radiotherapy-for-recurrent-or-persistent-cervical-cancer
#18
Seiji Mabuchi, Katsumi Kozasa, Tadashi Kimura
OBJECTIVE: To evaluate the safety and efficacy of radical hysterectomy after radiotherapy (RH-AR) for recurrent or persistent cervical cancer. METHODS: The present retrospective study included patients who underwent RH-AR for recurrent or persistent cervical cancer at Osaka University Hospital, Japan, between May 1, 2010 and September 30, 2016. Patient characteristics, intraoperative and postoperative adverse events, and surgical outcomes were investigated to identify patients at increased risk of recurrence or severe surgical adverse events...
July 28, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28749771/seroprevalence-of-brucellosis-among-patients-attending-a-district-hospital-in-rwanda
#19
James Gafirita, George Kiiza, Angelique Murekatete, Leonard L Ndahayo, John Tuyisenge, Vedaste Mashengesho, Rudoviko Ruhirwa, Theogene Nyandwi, Brenda Asiimwe-Kateera, Vedaste Ndahindwa, Kato J Njunwa
Studies on human brucellosis in Rwanda are scarce, and the incidence is likely to be higher than official estimates. In a recent study using Rose Bengal Test (RBT) on women who had aborted or had still births in Huye district, 25% were Brucella seroprevalent. Thus, purpose of the present study was to investigate the Brucella seroprevalence in patients presenting with the key signs and symptoms of brucellosis. Cross-sectional study was done in Nyagatare District in the Eastern Province of Rwanda. A total of 198 patients were recruited from Nyagatare District Hospital, blood samples were collected, and sera analyzed with RBT...
July 24, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28748509/clinical-characteristics-and-thrombosis-outcomes-of-paediatric-antiphospholipid-syndrome-analysis-of-58-patients
#20
Jingran Ma, Hongmei Song, Min Wei, Yanyan He
The study aims to analyse the clinical and immunological manifestations of paediatric antiphospholipid syndrome (APS) in patients, based on the 2006 revised classification criteria of definite APS. Fifty-eight paediatric patients with APS were enrolled and analysed retrospectively. A total of 37 female and 21 male patients with a mean age of 14 ± 3 years at disease onset were included. Fourteen (24%) cases were primary APS, and 40 (69%) cases were secondary to systemic lupus erythaematosus (SLE). Anti-nuclear antibody (ANA) positivity and hypocomplementemia were more common in secondary APS than in primary APS...
July 26, 2017: Clinical Rheumatology
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