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Anti-nutritional factors

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https://www.readbyqxmd.com/read/28103825/factors-behind-the-success-story-of-under-five-stunting-in-peru-a-district-ecological-multilevel-analysis
#1
Luis Huicho, Carlos A Huayanay-Espinoza, Eder Herrera-Perez, Eddy R Segura, Jessica Niño de Guzman, María Rivera-Ch, Aluisio J D Barros
BACKGROUND: Stunting prevalence in children less than 5 years has remained stagnated in Peru from 1992 to 2007, with a rapid reduction thereafter. We aimed to assess the role of different predictors on stunting reduction over time and across departments, from 2000 to 2012. METHODS: We used various secondary data sources to describe time trends of stunting and of possible predictors that included distal to proximal determinants. We determined a ranking of departments by annual change of stunting and of different predictors...
January 19, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28099236/intratracheal-instillation-of-perfluorohexane-modulates-the-pulmonary-immune-microenvironment-by-attenuating-early-inflammatory-factors-in-patients-with-smoke-inhalation-injury-a-randomized-controlled-clinical-trial
#2
Hui Ding, Qi Lv, Shiman Wu, Shike Hou, Ziquan Liu, Ning Xu Landén, Ping Tian, Mengyang Yu, Zhiguang Sun, Haojun Fan
Smoke inhalation injury (SII) is associated with significant morbidity and mortality in burn patients, and effective treatments are lacking. Perfluorocarbons (PFCs) have a protective effect against acute lung injury. We aimed to assess the therapeutic effects of perfluorohexane on burn patients with SII. Patients with burns complicated by moderately severe SII were randomly divided into control (n = 11) and PFC groups (n = 12). The control group received conventional treatment (anti-infection, nutritional support, antishock measures, and supportive treatment)...
January 10, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28078067/%C3%AE-linolenic-acid-reduces-tnf-induced-apoptosis-in-c2c12-myoblasts-by-regulating-expression-of-apoptotic-proteins
#3
Felicia Carotenuto, Dario Coletti, Paolo Di Nardo, Laura Teodori
Impaired regeneration and consequent muscle wasting is a major feature of muscle degenerative diseases. Nutritional interventions such as adjuvant strategy for preventing these conditions are recently gaining increasing attention. Ingestion of n3-polyunsaturated fatty acids has been suggested as having a positive impact on muscle diseases. We recently demonstrated that a diet enriched with plant derived n3-fatty acid, α-linolenic acid (ALA), exerts potent beneficial effects in preserving skeletal muscle regeneration in models of muscle dystrophy...
September 15, 2016: European Journal of Translational Myology
https://www.readbyqxmd.com/read/28076319/impact-of-nutrition-on-pollutant-toxicity-an-update-with-new-insights-into-epigenetic-regulation
#4
Jessie B Hoffman, Michael C Petriello, Bernhard Hennig
Exposure to environmental pollutants is a global health problem and is associated with the development of many chronic diseases, including cardiovascular disease, diabetes and metabolic syndrome. There is a growing body of evidence that nutrition can both positively and negatively modulate the toxic effects of pollutant exposure. Diets high in proinflammatory fats, such as linoleic acid, can exacerbate pollutant toxicity, whereas diets rich in bioactive and anti-inflammatory food components, including omega-3 fatty acids and polyphenols, can attenuate toxicant-associated inflammation...
January 11, 2017: Reviews on Environmental Health
https://www.readbyqxmd.com/read/28067935/hepatitis-b-vaccination-in-haemodialysis-patients-an-underestimated-problem-factors-influencing-immune-responses-in-ten-years-of-observation-in-an-italian-haemodialysis-centre-and-literature-review
#5
E Cordova, I Miglia, F Festuccia, M G Sarlo, G Scornavacca, G Punzo, P Menè, C Fofi
OBJECTIVES: Despite universal infection control precautions, the risk of hepatitis B virus (HBV) infection in patients on chronic haemodialysis (HD) remains high. For this reason anti-HBV vaccination is recommended in these subjects. In hemodialyzed patients vaccinal response is often suboptimal and it's not clear what factors may influence it. STUDY DESIGN: The aim of our study is to assess the influence of some clinical and laboratory factors on seroconversion rate after anti HBV vaccination in a cohort of patients on maintenance HD...
January 2017: Annali di Igiene: Medicina Preventiva e di Comunità
https://www.readbyqxmd.com/read/28050501/assessment-of-dental-nutrition-knowledge-among-nutrition-dietetics-students
#6
Salil Bapat, Kailash Asawa, Nagesh Bhat, Mridula Tak, Vivek V Gupta, Pulkit Chaturvedi, Hemasha Daryani, Kushal Shinde
INTRODUCTION: Diet and nutrition plays an important role in signifying the health of an individual. Oral health is the most important aspect of the body when it comes to food intake and its health benefits. It is important for the nutrition/dietetics students to be aware of the health modalities related to oral aspect. AIM: The aim of the present study was to assess knowledge towards the effect of diet and nutrition on oral health among nutrition/dietetics students of Udaipur city, Rajasthan, India...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28042591/relationship-between-nutritional-support-and-tuberculosis-treatment-outcomes-in-west-bengal-india
#7
Blesson Samuel, Tyson Volkmann, Sushma Cornelius, Sugata Mukhopadhay, MejoJose, Kaushik Mitra, Ajay M V Kumar, John E Oeltmann, Sidhajyoti Parija, Aslesh Ottapura Prabhakaran, Patrick K Moonan, Vineet K Chadha
INTRODUCTION: Poverty and poor nutrition are associated with the risk of developing tuberculosis (TB). Socioeconomic factors may interfere with anti-tuberculosis treatment compliance and its outcome. We examined whether providing nutritional support (monthly supply of rice and lentil beans) to TB patients who live below the poverty line was associated with TB treatment outcome. METHODS: This was a retrospective cohort study of sputum smear-positive pulmonary TB patients living below the poverty line (income of <$1...
December 2016: Journal of Tuberculosis Research
https://www.readbyqxmd.com/read/28031067/effects-of-faba-beans-with-different-concentrations-of-vicine-and-convicine-on-egg-production-egg-quality-and-red-blood-cells-in-laying-hens
#8
M Lessire, V Gallo, M Prato, O Akide-Ndunge, G Mandili, P Marget, P Arese, G Duc
The faba bean (Vicia faba L.) is a potential source of proteins for poultry, mainly for laying hens whose protein requirements are lower than those of other birds such as growing broilers and turkeys. However, this feedstuff contains anti-nutritional factors, that is, vicine (V) and convicine (C) that are already known to reduce laying hen performance. The aim of the experiment reported here was to evaluate the effects of a wide range of dietary V and C concentrations in laying hens. Two trials were performed with laying hens fed diets including 20% or 25% of faba bean genotypes highly contrasting in V+C content...
December 29, 2016: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28028995/recommendations-for-optimizing-tuberculosis-treatment-therapeutic-drug-monitoring-pharmacogenetics-and-nutritional-status-considerations
#9
REVIEW
Rihwa Choi, Byeong Ho Jeong, Won Jung Koh, Soo Youn Lee
Although tuberculosis is largely a curable disease, it remains a major cause of morbidity and mortality worldwide. Although the standard 6-month treatment regimen is highly effective for drug-susceptible tuberculosis, the use of multiple drugs over long periods of time can cause frequent adverse drug reactions. In addition, some patients with drug-susceptible tuberculosis do not respond adequately to treatment and develop treatment failure and drug resistance. Response to tuberculosis treatment could be affected by multiple factors associated with the host-pathogen interaction including genetic factors and the nutritional status of the host...
March 2017: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/28025954/anti-inflammatory-effects-of-an-oxylipin-containing-lyophilised-biomass-from-a-microalga-in-a-murine-recurrent-colitis-model
#10
Javier Ávila-Román, Elena Talero, Azahara Rodríguez-Luna, Sofía García-Mauriño, Virginia Motilva
Diet and nutritional factors have emerged as possible interventions for inflammatory bowel diseases (IBD), which are characterised by chronic uncontrolled inflammation of the intestinal mucosa. Microalgal species are a promising source of n-3 PUFA and derived oxylipins, which are lipid mediators with a key role in the resolution of inflammation. The aim of the present study was to investigate the effects of an oxylipin-containing lyophilised biomass from Chlamydomonas debaryana on a recurrent 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis mice model...
December 2016: British Journal of Nutrition
https://www.readbyqxmd.com/read/28025123/structured-dag-oil-ameliorates-renal-injury-in-streptozotocin-induced-diabetic-rats-through-inhibition-of-nf-%C3%AE%C2%BAb-and-activation-of-nrf2-pathway
#11
Kankana Das, Mahua Ghosh
Accumulating evidence suggested that inflammatory processes are involved in the development of diabetic nephropathy (DN). Here, we have tested the hypothesis that Caprylic Acid (Cy)-diacylglycerol (DAG) oil (Cy-DAG), a novel structurally formulated lipid with high nutritional value, ameliorated DN in streptozotocin (STZ)-induced diabetic rats through the anti-inflammatory mechanisms. Basic hematological, biochemical parameters, immunoblotting, immunofluorescence and flow cytometry analysis were performed to observe the anti-inflammatory potential of Cy-DAG oil...
December 24, 2016: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28011640/regulation-of-ulk1-expression-and-autophagy-by-stat1
#12
Alexander A Goldberg, Bernard Nkengfac, Anthony M J Sanchez, Nikolay Moroz, Salman T Qureshi, Antonis E Koromilas, Shuo Wang, Yan Burelle, Sabah N Hussain, Arnold S Kristof
Autophagy involves the lysosomal degradation of cytoplasmic contents for regeneration of anabolic substrates during nutritional or inflammatory stress. Its initiation occurs rapidly after inactivation of the protein- kinase 'mammalian target of rapamycin' (mTOR; or 'mechanistic target of rapamycin', MTOR), leading to de-phosphorylation of Unc-51-like kinase 1 (ULK1) and autophagosome formation. Recent studies indicate that mTOR can, in parallel, regulate the activity of stress transcription factors, including 'signal transducer and activator of transcription-1' (STAT1)...
December 23, 2016: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28004617/hydrolysable-tannin-based-diet-rich-in-gallotannins-has-a-minimal-impact-on-pig-performance-but-significantly-reduces-salivary-and-bulbourethral-gland-size
#13
G Bee, P Silacci, S Ampuero-Kragten, M Čandek-Potokar, A L Wealleans, J Litten-Brown, J-P Salminen, I Mueller-Harvey
Tannins have long been considered 'anti-nutritional' factors in monogastric nutrition, shown to reduce feed intake and palatability. However, recent studies revealed that compared with condensed tannins, hydrolysable tannins (HT) appear to have far less impact on growth performance, but may be inhibitory to the total activity of caecal bacteria. This in turn could reduce microbial synthesis of skatole and indole in the hindgut of entire male pigs (EM). Thus, the objective of this study was to determine the impact of a group of dietary HT on growth performance, carcass traits and boar taint compounds of group housed EM...
December 22, 2016: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/27999406/natural-products-in-anti-obesity-therapy
#14
EDITORIAL
Filomena Conforti, Min-Hsiung Pan
Obesity is regulated by genetic, endocrine, metabolic, neurological, pharmacological, environmental, and nutritional factors. [...].
December 20, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27998828/nutritionally-relevant-concentrations-of-resveratrol-and-hydroxytyrosol-mitigate-oxidative-burst-of-human-granulocytes-and-monocytes-and-the-production-of-pro-inflammatory-mediators-in-lps-stimulated-raw-264-7-macrophages
#15
Elisabetta Bigagli, Lorenzo Cinci, Sara Paccosi, Astrid Parenti, Mario D'Ambrosio, Cristina Luceri
The health benefits of bio-active phenolic compounds have been largely investigated in vitro at concentrations which exceed those reachable in vivo. We investigated and compared the anti-inflammatory effects of resveratrol, hydroxytyrosol and oleuropein at physiologically relevant concentrations by using in vitro models of inflammation. Human granulocytes and monocytes were stimulated with phorbol myristate acetate (PMA) and the ability of resveratrol, hydroxytyrosol and oleuropein to inhibit the oxidative burst and CD11b expression was measured...
February 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/27995503/improvement-of-anti-nutritional-effect-resulting-from-%C3%AE-glucanase-specific-expression-in-the-parotid-gland-of-transgenic-pigs
#16
Li-Zeng Guan, Jin-Shun Cai, Shuai Zhao, Yu-Ping Sun, Jing-Lan Wang, Yong Jiang, Gang Shu, Qing-Yan Jiang, Zhen-Fang Wu, Qian-Yun Xi, Yong-Liang Zhang
β-Glucan is the predominant anti-nutritional factors in monogastric animal feed. Although β-glucanase supplementation in diet can help to eliminate the adverse effects, enzyme stability is substantially modified during the feed manufacturing process. To determine whether the expression of endogenous β-glucanase gene (GLU) in vivo can improve digestibility of dietary β-glucan and absorption of nutrients, we successfully produced transgenic pigs via nuclear transfer which express the GLU from Paenibacillus polymyxa CP7 in the parotid gland...
February 2017: Transgenic Research
https://www.readbyqxmd.com/read/27983724/helminth-burden-and-ecological-factors-associated-with-alterations-in-wild-host-gastrointestinal-microbiota
#17
Lindsay K Newbold, Sarah J Burthe, Anna E Oliver, Hyun S Gweon, Christopher J Barnes, Francis Daunt, Christopher J van der Gast
Infection by gastrointestinal helminths of humans, livestock and wild animals is common, but the impact of such endoparasites on wild hosts and their gut microbiota represents an important overlooked component of population dynamics. Wild host gut microbiota and endoparasites occupy the same physical niche spaces with both affecting host nutrition and health. However, associations between the two are poorly understood. Here we used the commonly parasitized European shag (Phalacrocorax aristotelis) as a model wild host...
December 16, 2016: ISME Journal
https://www.readbyqxmd.com/read/27965645/glucose-induces-ecf-sigma-factor-genes-sigx-and-sigm-independent-of-cognate-anti-sigma-factors-through-acetylation-of-csha-in-bacillus-subtilis
#18
Mitsuo Ogura, Kei Asai
Extracytoplasmic function (ECF) σ factors have roles related to cell envelope and/or cell membrane functions, in addition to other cellular functions. Without cell-surface stresses, ECF σ factors are sequestered by the cognate anti-σ factor, leading to inactivation and the resultant repression of regulons due to the inhibition of transcription of their own genes. Bacillus subtilis has seven ECF σ factors including σ(X) and σ(M) that transcribe their own structural genes. Here, we report that glucose addition to the medium induced sigX and sigM transcription independent of their anti-σ factors...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27928964/hot-topics-in-pharmacogenetics-of-age-related-macular-degeneration
#19
Stephen G Schwartz, Milam A Brantley, Jaclyn L Kovach, Andrzej Grzybowski
Age-related macular degeneration (AMD) is a leading cause of irreversible visual loss and is primarily treated with nutritional supplementation as well as with anti-vascular endothelial growth factor (VEGF) agents for certain patients with neovascular disease. AMD is a complex disease with both genetic and environmental risk factors. In addition, treatment outcomes from nutritional supplementation and anti-VEGF agents vary considerably. Therefore, it is reasonable to suspect that there may be pharmacogenetic influences on these treatments...
December 8, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27924588/antioxidant-micronutrients-and-oxidative-stress-biomarkers
#20
Iain L C Chapple, Helen R Griffiths, Mike R Milward, Martin R Ling, Melissa M Grant
Chronic inflammatory diseases are the major causes of mortality in humans and recent research has improved our understanding of the major impact of life-style factors upon inflammatory diseases and conditions. One of the most influential of these is nutrition, which may drive both pro-inflammatory as well as anti-inflammatory cascades at molecular and cellular levels. There are a variety of model systems that may be employed to investigate the impact of micronutrients and macronutrients upon inflammatory pathways, many of which operate through oxidative stress, either at the level of controlling the redox state of the cell and downstream redox-regulated gene transcription factors, and other acting as free radical generating or scavenging agents...
2017: Methods in Molecular Biology
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