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https://www.readbyqxmd.com/read/28820724/neurologic-complications-in-persons-with-hiv-infection-in-the-era-of-antiretroviral-therapy
#1
Dennis Kolson
Neurologic complications in persons with HIV infection are less severe in the era of potent antiretroviral therapy but remain highly prevalent. Prior to the use of antiretroviral therapy, opportunistic infections of the central nervous system (CNS) and CNS malignancy were common. Progressive multifocal leukoencephalopathy (PML), however, remains a diagnostic challenge in HIV-infected individuals, and no effective antiviral treatment for PML is currently available. Primary neurologic complications of acute HIV infection include aseptic meningitis and acute inflammatory demyelinating polyneuropathy...
July 2017: Topics in Antiviral Medicine
https://www.readbyqxmd.com/read/28819778/impact-of-jumihaidokuto-shi-wei-bai-du-tang-on-treatment-of-chronic-spontaneous-urticaria-a-randomized-controlled-study
#2
Hiroyuki Murota, Hiroaki Azukizawa, Ichiro Katayama
OBJECTIVE: To study the effect of Jumihaidokuto (Shi-Wei-Bai-Du-Tang, ) in the management of chronic spontaneous urticaria. METHODS: A randomized two-arm, parallel group study was conducted to compare the effect of Jumihaidokuto (6 g daily) with a control for 8 weeks. Concomitant therapy (e.g., antihistamines) was continued. Twenty-one subjects with severe chronic urticaria were enrolled in this study. The primary treatment outcome was the severity score proposed by the Japanese Dermatological Association...
August 17, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28817647/caprine-brucellosis-a-historically-neglected-disease-with-significant-impact-on-public-health
#3
REVIEW
Carlos A Rossetti, Angela M Arenas-Gamboa, Estefanía Maurizio
Caprine brucellosis is a chronic infectious disease caused by the gram-negative cocci-bacillus Brucella melitensis. Middle- to late-term abortion, stillbirths, and the delivery of weak offspring are the characteristic clinical signs of the disease that is associated with an extensive negative impact in a flock's productivity. B. melitensis is also the most virulent Brucella species for humans, responsible for a severely debilitating and disabling illness that results in high morbidity with intermittent fever, chills, sweats, weakness, myalgia, abortion, osteoarticular complications, endocarditis, depression, anorexia, and low mortality...
August 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28814278/epidemiology-and-outcomes-of-endophthalmitis-in-chronic-dialysis-patients-a-13-year-experience-in-a-tertiary-referral-center-in-taiwan
#4
George Kuo, Yueh-An Lu, Wei-Chiao Sun, Chao-Yu Chen, Huang-Kai Kao, YuJr Lin, Chia-Hui Lee, Cheng-Chieh Hung, Ya-Chung Tian, Hsiang-Hao Hsu
BACKGROUND: Endophthalmitis is a severe eye infection leading to disabling outcome. Because there were only a few case report illustrating endophthalmitis in chronic dialysis patient, we would like to investigate the epidemiology and clinical features of endophthalmitis in chronic dialysis patient in a tertiary referral center. METHODS: We searched the health information system in the study hospital with ICD9 encoding endophthalmitis during Jan. 2002 to Dec. 2015...
August 16, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28812209/effect-of-vitamin-d-supplementation-in-chronic-widespread-pain-a-systematic-review-and-meta-analysis
#5
Wai Chung Yong, Anawin Sanguankeo, Sikarin Upala
Chronic non-specific widespread pain (CWP) including fibromyalgia (FMS) is characterized by widespread pain, reduced pain threshold, and multiple tender points on examination, causing disability and decreased quality of life. Vitamin D has been proposed as an associated factor in CWP. This meta-analysis aimed to explore the benefit of vitamin D supplementation in the management of CWP. A comprehensive search of the CENTRAL, MEDLINE, and Embase databases was performed from inception through January 2017. The inclusion criterion was the randomized clinical trials' evaluating the effects of vitamin D treatment in adult subjects with CWP or FMS...
August 15, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28812150/respiratory-complications-after-colonic-procedures-in-chronic-obstructive-pulmonary-disease-does-laparoscopy-offer-a-benefit
#6
Sarath Sujatha-Bhaskar, Reza Fazl Alizadeh, Colette S Inaba, Christina Y Koh, Mehraneh D Jafari, Steven D Mills, Joseph C Carmichael, Michael J Stamos, Alessio Pigazzi
BACKGROUND: Patients with severe chronic obstructive pulmonary disease (COPD) are at a higher risk for postoperative respiratory complications. Despite the benefits of a minimally invasive approach, laparoscopic pneumoperitoneum can substantially reduce functional residual capacity and raise alveolar dead space, potentially increasing the risk of respiratory failure which may be poorly tolerated by COPD patients. This raises controversy as to whether open techniques should be preferentially employed in this population...
August 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28811041/post-thrombotic-syndrome-in-children
#7
Marisol Betensky, Neil A Goldenberg
The post-thrombotic syndrome (PTS) is the most common long-term complication of pediatric deep venous thrombosis (DVT). It is a burdensome condition that can lead to severe disability and poor quality-of-life of affected children. Although its pathophysiology remains poorly understood, it is thought to be the result of chronic venous hypertension. Recent studies have shown that the inflammatory response associated with an acute DVT likely plays a key role in the development of PTS. The Manco-Johnson Instrument and the modified Villalta Scale are the most widely used instruments for the diagnosis of pediatric PTS...
July 24, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/28807742/a-cost-utility-analysis-of-dynesys-dynamic-stabilization-versus-instrumented-fusion-for-the-treatment-of-degenerative-lumbar-spine-diseases
#8
Kan Liu, Wei Sun, Qiang Lu, Jiying Chen, Jiaguang Tang
BACKGROUND: Symptomatic chronic low back and leg pain resulting from lumbar spine degenerative disorders is highly prevalent in China, and for some patients, surgery is the final option for improvement. Several techniques for spinal non-fusion have been introduced to reduce the side-effects of fusion methods and hasten postoperative recovery. In this study, the authors have evaluated the cost-effectiveness of Dynesys posterior dynamic stabilization system (DY) compared with lumbar fusion techniques in the treatment of single-level degenerative lumbar spinal conditions...
August 11, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28806436/effectiveness-of-a-timing-and-coordination-group-exercise-program-to-improve-mobility-in-community-dwelling-older-adults-a-randomized-clinical-trial
#9
Jennifer S Brach, Subashan Perera, Sandra Gilmore, Jessie M VanSwearingen, Deborah Brodine, Neelesh K Nadkarni, Edmund Ricci
Importance: Timing and coordination exercises may be an important addition to community-based health promotion exercise programs to improve walking in older adults. Objective: To compare the effectiveness of the On the Move group exercise program, which focuses on the timing and coordination of movement, with a seated strength, endurance, and flexibility program (usual care) at improving function, disability, and walking ability of older adults. Design, Setting, and Participants: Cluster-randomized, single-blind intervention trial...
August 14, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28806206/chronic-pain-and-associated-factors-in-india-and-nepal-a-pilot-study-of-the-vanderbilt-global-pain-survey
#10
Jenna L Walters, Kelly Baxter, Hannah Chapman, Tracy Jackson, Adinarayanan Sethuramachandran, Marcus Couldridge, Hem Raj Joshi, Pankaj Kundra, Xulei Liu, Divya Nair, Bonnie Sullivan, Matthew S Shotwell, Ryan J Jense, Nicholas J Kassebaum, K A Kelly McQueen
BACKGROUND: Evaluation and treatment of chronic pain worldwide are limited by the lack of standardized assessment tools incorporating consistent definitions of pain chronicity and specific queries of known social and psychological risk factors for chronic pain. The Vanderbilt Global Pain Survey (VGPS) was developed as a tool to address these concerns, specifically in the low- and middle-income countries where global burden is highest. METHODS: The VGPS was developed using standardized and cross-culturally validated metrics, including the Brief Pain Inventory and World Health Organization Disability Assessment Scale, as well as the Pain Catastrophizing Scale, the Fibromyalgia Survey Questionnaire along with queries about pain attitudes to assess the prevalence of chronic pain and disability along with its psychosocial and emotional associations...
August 10, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28806092/comparable-outcomes-after-bucket-handle-meniscal-repair-and-vertical-meniscal-repair-can-be-achieved-at-a-minimum-2-years-follow-up
#11
Gilbert Moatshe, Mark E Cinque, Jonathan A Godin, Alexander R Vap, Jorge Chahla, Robert F LaPrade
BACKGROUND: Meniscal tears can lead to significant pain and disability, necessitating surgical treatment. Nondisplaced vertical tears are usually smaller in size and can be repaired in most cases; however, bucket-handle tears are usually larger and displaced, and the repair of these tears can be challenging. Purpose/Hypothesis: The purpose was to report the outcomes after inside-out vertical mattress suture meniscal repair of bucket-handle tears and to compare these outcomes with those of patients who underwent repair of nondisplaced vertical meniscal tears with a minimum of 2 years' follow-up...
August 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28805580/tourette-syndrome-and-chronic-tic-disorders-the-clinical-spectrum-beyond-tics
#12
Davide Martino, Christos Ganos, Tamara M Pringsheim
The clinical surveillance and active management of Tourette syndrome (TS) and other primary chronic tic disorders cannot be limited to tics, as these patients manifest a spectrum of sensory-, behavioral-, cognitive-, and sleep-related problems that have a major impact on their functioning and quality of life, influencing enormously clinical decision making on a routine basis. The sensory phenomena of primary tic disorders consist of premonitory urges and heightened sensitivity to external somatosensory and interoceptive stimuli...
2017: International Review of Neurobiology
https://www.readbyqxmd.com/read/28805423/patterns-of-psychiatric-emergency-department-utilization-among-community-dwelling-medicare-beneficiaries-under-65
#13
Jingjing Qian, Saranrat Wittayanukorn, Richard A Hansen
This study estimated patterns and trends in all-cause (any reason, including psychiatry related) and psychiatric emergency department (ED) utilization among Medicare beneficiaries under 65 who were residing in community settings (i.e., noninstitutionalized or in their own homes). Medicare beneficiaries under the age of 65 enrolled in Medicare for Social Security Disability Insurance (SSDI) due to permanent physical or mental disabilities are a population with poor health conditions and high utilization of health services; however, this vulnerable population has received limited attention from researchers and policymakers compared to the Medicare beneficiaries 65 years and older...
August 2017: Psychological Services
https://www.readbyqxmd.com/read/28804504/efficacy-of-auricular-acupressure-for-chronic-low-back-pain-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#14
REVIEW
Li-Hua Yang, Pei-Bei Duan, Qing-Mei Hou, Shi-Zheng Du, Jin-Fang Sun, Si-Juan Mei, Xiao-Qing Wang
OBJECTIVES: To identify the efficacy of auricular acupressure on pain and disability for chronic LBP by systematic review. METHODS: A search of randomized controlled trials was conducted in four English medical electronic databases and three Chinese databases. Two reviewers independently retrieved related studies, assessed the methodological quality, and extracted data with a standardized data form. Meta-analyses were performed using all time-points meta-analysis...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28804385/depression-statuses-and-related-predictors-in-later-life-a-10-year-follow-up-study-in-israel
#15
Rabia Khalaila
The aim of the current study was to investigate the factors associated with depression statuses in a 10-year follow-up of community-dwelling older adults in Israel. Longitudinal data were used from the Israeli sample of the Survey of Health, Aging and Retirement in Europe, assessing the depressive symptoms in 1042 respondents, aged 50 or above, at three time points: 2004/2005 (Wave I); 2009/2010 (Wave II); and 2014/2015 (Wave III). Multinomial logistic regression was used to determine the relationships among explanatory variables and depression statuses (no-depression, intermittent depression, or persistent depression)...
December 2016: European Journal of Ageing
https://www.readbyqxmd.com/read/28804246/the-role-of-functional-social-and-mobility-dynamics-in-facilitating-older-african-americans-participation-in-clinical-research
#16
Eve T Shapiro, Jay T Schamel, Kimberly A Parker, Laura A Randall, Paula M Frew
PURPOSE: Older African Americans experience disproportionately higher incidence of morbidity and mortality related to chronic and infectious diseases, yet are significantly underrepresented in clinical research compared to other racial and ethnic groups. This study aimed to understand the extent to which social support, transportation access, and physical impediments function as barriers or facilitators to clinical trial recruitment of older African Americans. METHODS: Participants (N=221) were recruited from six African American churches in Atlanta and surveyed on various influences on clinical trial participation...
2017: Open Access Journal of Clinical Trials
https://www.readbyqxmd.com/read/28803624/the-quality-of-primary-care-provided-by-nurse-practitioners-to-vulnerable-medicare-beneficiaries
#17
Catherine M DesRoches, Sean Clarke, Jennifer Perloff, Monica O'Reilly-Jacob, Peter Buerhaus
BACKGROUND: Studies suggest nurse practitioners are heavily represented among primary care providers for vulnerable Medicare beneficiaries. PURPOSE: The purpose of this study was to compare quality indicators among three groups of vulnerable beneficiaries managed by MDs and nurse practitioners (NPs). METHODS: The methods include retrospective cohort design examining 2012 and 2013 Medicare claims for three beneficiary groups: (a) initially qualified for the program due to disability, (b) dually eligible for Medicare and Medicaid, and (c) both disabled and dually eligible...
June 15, 2017: Nursing Outlook
https://www.readbyqxmd.com/read/28798049/patient-reported-outcomes-from-a-phase-3-study-of-baricitinib-versus-placebo-or-adalimumab-in-rheumatoid-arthritis-secondary-analyses-from-the-ra-beam-study
#18
Edward C Keystone, Peter C Taylor, Yoshiya Tanaka, Carol Gaich, Amy M DeLozier, Anna Dudek, Jorge Velasco Zamora, Jose Arturo Covarrubias Cobos, Terence Rooney, Stephanie de Bono, Vipin Arora, Bruno Linetzky, Michael E Weinblatt
BACKGROUND: To assess the effect of baricitinib on patient-reported outcomes (PROs) in patients with active rheumatoid arthritis and an inadequate response to methotrexate (MTX). METHODS: In this double-blind phase 3 study, patients were randomised 3:3:2 to placebo (n=488), baricitinib 4 mg once daily (n=487), or adalimumab 40 mg biweekly (n=330) with background MTX. PROs included the SF-36, EuroQol 5-D (EQ-5D) index scores and visual analogue scale, Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F), Health Assessment Questionnaire-Disability Index (HAQ-DI), Patient's Global Assessment of Disease Activity (PtGA), patient's assessment of pain and Work Productivity and Activity Impairment Questionnaire-Rheumatoid Arthritis (WPAI-RA), and measures collected in electronic patient daily diaries: duration and severity of morning joint stiffness (MJS), Worst Ttiredness and Worst Joint Pain...
August 10, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28791026/decrease-of-markers-related-to-bone-erosion-in-serum-of-patients-with-musculoskeletal-disorders-after-serial-low-dose-radon-spa-therapy
#19
Aljona Cucu, Kateryna Shreder, Daniela Kraft, Paul Friedrich Rühle, Gerhart Klein, Gerhard Thiel, Benjamin Frey, Udo S Gaipl, Claudia Fournier
Musculoskeletal disorders (MSDs) are the most frequent cause of disability in Europe. Reduced mobility and quality of life of the patients are often associated with pain due to chronic inflammation. The inflammatory process, accompanied by a destruction of the cartilage and bone tissue, is discussed as a result of (A) the infiltration of immune cells into the joints, (B) an altered homeostasis of the joint cavity (synovium) with a critical role of bone remodeling cells, and (C) release of inflammatory factors including adipokines in the arthritic joint...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28790872/cognitive-behavioral-therapy-for-patients-with-irritable-bowel-syndrome-current-insights
#20
REVIEW
Sarah W Kinsinger
Irritable bowel syndrome (IBS) is a chronic gastrointestinal (GI) condition associated with significant health care utilization and quality-of-life impairment. Latest research indicates that the brain-gut axis plays a key role in the disorder, and the presence of psychological factors and central processing deficits contribute to symptom severity and disability. Psychological therapies as a whole have demonstrated good efficacy in reducing the severity of IBS symptoms. Cognitive-behavioral therapy (CBT) has been tested most rigorously in multiple randomized controlled trials and consistently demonstrates significant and durable effects on IBS symptoms and quality of life...
2017: Psychology Research and Behavior Management
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