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https://www.readbyqxmd.com/read/29326354/accuracy-of-dose-calibrators-for-gallium-68-pet-imaging-unexpected-findings-in-a-multi-centre-clinical-pre-trial-assessment
#1
Dale L Bailey, Michael S Hofman, Nicholas J Forwood, Graeme J O'Keefe, Andrew M Scott, Winifred M van Wyngaardt, Bonnie Howe, Olga Kovacev, Roslyn J Francis
AIMS: We report the discovery of a systematic miscalibration during the work-up process for site validation of a multi-centre clinical PET imaging trial using 68Ga, which manifested as a consistent and reproducible underestimation in the quantitative accuracy (assessed by SUV) of a range of PET cameras from different manufacturers at a number of different facilities around Australia. METHODS: Sites were asked to follow a strict preparation protocol to create a radioactive phantom with 68Ga to be imaged using a standard clinical protocol prior to commencing imaging in the trial...
January 11, 2018: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29295637/clostridial-collagenase-ointment-and-medicinal-honey-utilization-for-pressure-ulcers-in-u-s-hospitals
#2
Jill Dreyfus, Gary Delhougne, Bobbie James, Julie Gayle, Curtis Waycaster
AIMS: Describe the utilization of clostridial collagenase ointment (CCO) and medicinal honey debridement methods in real-world inpatient and outpatient hospital settings among pressure ulcer (PU) patients and compare the frequency of healthcare re-encounters between CCO- and medicinal honey-treated patients. MATERIALS AND METHODS: De-identified hospital discharge records for patients receiving CCO or medicinal honey methods of debridement and having an ICD-9 code for PU were extracted from the U...
January 3, 2018: Journal of Medical Economics
https://www.readbyqxmd.com/read/29291493/89zr-for-antibody-labeling-and-in-vivo-studies-a-comparison-between-liquid-and-solid-target-production
#3
Gemma M Dias, Caterina F Ramogida, Julie Rousseau, Nicholas A Zacchia, Cornelia Hoehr, Paul Schaffer, Kuo-Shyan Lin, François Bénard
INTRODUCTION: Zirconium-89 (89Zr, t1/2=78.4h) liquid target (LT) production offers an approach to introduce this positron-emitting isotope to cyclotron centres without the need for a separate solid target (ST) production set up. We compared the production, purification, and antibody radiolabeling yields of 89Zr-(LT) and 89Zr-(ST), and assessed the feasibility of 89Zr-(LT) for preclinical PET/CT. METHODS: 89Zr-(ST) production was performed with an 89Y foil on a TR 19 cyclotron at 13...
November 16, 2017: Nuclear Medicine and Biology
https://www.readbyqxmd.com/read/29284699/what-factors-contribute-to-postabortion-contraceptive-uptake-by-young-women-a-program-evaluation-in-10-countries-in-asia-and-sub-saharan-africa
#4
Janie Benson, Kathryn Andersen, Joan Healy, Dalia Brahmi
BACKGROUND: Unintended pregnancy disproportionately affects young women and adolescents in developing countries. The abortion care setting offers a unique opportunity for adolescents and young women to access a full range of contraceptive services. This evaluation assesses the factors that influence contraceptive uptake among adolescents and young women seeking abortion care in health facilities. METHODS: Following provider training, we analyzed client log book data from 921,918 abortion care cases in 4,881 health facilities in 10 countries from July 2011 through June 2015...
December 28, 2017: Global Health, Science and Practice
https://www.readbyqxmd.com/read/29248605/pain-treatment-practices-of-community-dwelling-black-older-adults
#5
Sheria G Robinson-Lane, April Hazard Vallerand
Black older adults often experience disparities in pain treatment that results in unmet pain needs. The aims of this study were to assess the pain management experiences of a group of community dwelling Black older adults and identify gaps in clinical practice. A qualitative, descriptive design was employed using the methodology of ethnography. The setting was an urban, low-income, community elderly housing high-rise facility. Participants included facility residents (n = 106); of these, 20 completed structured qualitative interviews...
December 13, 2017: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
https://www.readbyqxmd.com/read/29241602/the-incidence-of-abortion-and-unintended-pregnancy-in-india-2015
#6
Susheela Singh, Chander Shekhar, Rajib Acharya, Ann M Moore, Melissa Stillman, Manas R Pradhan, Jennifer J Frost, Harihar Sahoo, Manoj Alagarajan, Rubina Hussain, Aparna Sundaram, Michael Vlassoff, Shveta Kalyanwala, Alyssa Browne
BACKGROUND: Reliable information on the incidence of induced abortion in India is lacking. Official statistics and national surveys provide incomplete coverage. Since the early 2000s, medication abortion has become increasingly available, improving the way women obtain abortions. The aim of this study was to estimate the national incidence of abortion and unintended pregnancy for 2015. METHODS: National abortion incidence was estimated through three separate components: abortions (medication and surgical) in facilities (including private sector, public sector, and non-governmental organisations [NGOs]); medication abortions outside facilities; and abortions outside of facilities and with methods other than medication abortion...
January 2018: Lancet Global Health
https://www.readbyqxmd.com/read/29220067/gene-expression-and-fatigue-in-puerto-rican-men-during-radiotherapy-for-prostate-cancer-an-exploratory-study
#7
Velda J Gonzalez, Leorey N Saligan, Brooke L Fridley, Humberto Ortiz-Zuazaga, Lauren S Aaronson
OBJECTIVE: To examine the trajectory of fatigue experienced by 26 Puerto Rican (PR) men over the course of External Beam Radiation Therapy (EBRT) and to assess gene expression changes from baseline to midpoint of EBRT using microarray technology. Design/Research Approach- Prospective exploratory and comparative design study. Setting- RT facility located in San Juan, PR. Sample/Participants-26 PR men with non-metastatic prostate cancer. METHODS: Participants completed 2 paper forms: demographics and the Spanish version of the 13-item FACT-fatigue at baseline, midpoint, and end of EBRT...
December 2017: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/29207973/identifying-models-of-hiv-care-and-treatment-service-delivery-in-tanzania-uganda-and-zambia-using-cluster-analysis-and-delphi-survey
#8
Sharon Tsui, Julie A Denison, Caitlin E Kennedy, Larry W Chang, Olivier Koole, Kwasi Torpey, Eric Van Praag, Jason Farley, Nathan Ford, Leine Stuart, Fred Wabwire-Mangen
BACKGROUND: Organization of HIV care and treatment services, including clinic staffing and services, may shape clinical and financial outcomes, yet there has been little attempt to describe different models of HIV care in sub-Saharan Africa (SSA). Information about the relative benefits and drawbacks of different models could inform the scale-up of antiretroviral therapy (ART) and associated services in resource-limited settings (RLS), especially in light of expanded client populations with country adoption of WHO's test and treat recommendation...
December 6, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29201657/tuberculosis-among-migrants-in-bishkek-the-capital-of-the-kyrgyz-republic
#9
O Goncharova, O Denisiuk, R Zachariah, K Davtyan, D Nabirova, C Acosta, A Kadyrov
Setting: Twenty-two first-line, two second-line and one tertiary health facility in Bishkek, the capital of Kyrgyzstan. Objectives: Among migrants, a marginalised population at risk for acquiring and transmitting tuberculosis (TB), we determined the proportion with TB among all registered TB cases. For those registered at primary-level facilities, we then reported on their demographic and clinical profiles and TB treatment outcomes. Design: This was a retrospective cohort analysis of 2012-2013 programme data...
September 21, 2017: Public Health Action
https://www.readbyqxmd.com/read/29182800/interventions-to-increase-tuberculosis-case-detection-at-primary-healthcare-or-community-level-services
#10
REVIEW
Francis A Mhimbira, Luis E Cuevas, Russell Dacombe, Abdallah Mkopi, David Sinclair
BACKGROUND: Pulmonary tuberculosis is usually diagnosed when symptomatic individuals seek care at healthcare facilities, and healthcare workers have a minimal role in promoting the health-seeking behaviour. However, some policy specialists believe the healthcare system could be more active in tuberculosis diagnosis to increase tuberculosis case detection. OBJECTIVES: To evaluate the effectiveness of different strategies to increase tuberculosis case detection through improving access (geographical, financial, educational) to tuberculosis diagnosis at primary healthcare or community-level services...
November 28, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29150866/the-minimum-test-battery-to-screen-for-binocular-vision-anomalies-report-3-of-the-band-study
#11
Jameel Rizwana Hussaindeen, Archayeeta Rakshit, Neeraj Kumar Singh, Meenakshi Swaminathan, Ronnie George, Suman Kapur, Mitchell Scheiman, Krishna Kumar Ramani
PURPOSE: This study aims to report the minimum test battery needed to screen non-strabismic binocular vision anomalies (NSBVAs) in a community set-up. When large numbers are to be screened we aim to identify the most useful test battery when there is no opportunity for a more comprehensive and time-consuming clinical examination. METHODS: The prevalence estimates and normative data for binocular vision parameters were estimated from the Binocular Vision Anomalies and Normative Data (BAND) study, following which cut-off estimates and receiver operating characteristic curves to identify the minimum test battery have been plotted...
November 18, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29143609/survey-of-programmatic-experiences-and-challenges-in-delivery-of-hepatitis-b-and-c-testing-in-low-and-middle-income-countries
#12
Azumi Ishizaki, Julie Bouscaillou, Niklas Luhmann, Stephanie Liu, Raissa Chua, Nick Walsh, Sarah Hess, Elena Ivanova, Teri Roberts, Philippa Easterbrook
BACKGROUND: There have been few reports on programmatic experience of viral hepatitis testing and treatment in resource-limited settings. To inform the development of the 2017 World Health Organization (WHO) viral hepatitis testing guidance and in particular the feasibility of proposed recommendations, we undertook a survey across a range of organisations engaged with hepatitis testing in low- and middle-income countries (LMICs). Our objective was to describe current hepatitis B and C testing practices across a range of settings in different countries, as well as key barriers or challenges encountered and proposed solutions to promote testing scale-up...
November 1, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29132283/predictors-of-survival-among-hiv-positive-children-on-art-in-swaziland
#13
Patrick Shabangu, Andy Beke, Samuel Manda, Nobuhle Mthethwa
The objective of the study was to determine predictors of survival among HIV-positive children (<15 years) in Swaziland. A retrospective cohort analysis of medical records for 4 167 children living with HIV who were initiated on antiretroviral therapy (ART) between 2004 and 2008, and followed up until 2014 was conducted in clinical settings at 36 health facilities. The Kaplan Meier Estimator, signed-ranks test, and the Cox proportional hazards regression model were applied to determine survival probabilities, significant difference among stratified survival functions and adjusted hazard ratios respectively...
December 2017: African Journal of AIDS Research: AJAR
https://www.readbyqxmd.com/read/29130440/development-and-pilot-evaluation-of-a-novel-theory-based-intervention-to-encourage-help-seeking-for-adult-hearing-loss
#14
Gabrielle H Saunders, Melissa T Frederick, ShienPei C Silverman, Claus Nielsen, Ariane Laplante-Lévesque
BACKGROUND: Health behavior theories can provide an understanding of hearing health behaviors and, more importantly, can be used to develop theoretically based strategies to change these health behaviors. PURPOSE: To develop a theory-based brief intervention to increase help-seeking for adult hearing loss and to conduct a pilot study to evaluate its feasibility, effectiveness, and impact on hearing beliefs and behaviors. RESEARCH DESIGN: An intervention was designed that could be easily administered by a health-care provider who does not have expertise in audiology-such as a primary care physician, community nurse, or social worker...
November 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/29117959/barriers-and-facilitators-to-provide-quality-tia-care-in-the-veterans-healthcare-administration
#15
Teresa M Damush, Edward J Miech, Jason J Sico, Michael S Phipps, Greg Arling, Jared Ferguson, Charles Austin, Laura Myers, Fitsum Baye, Cherie Luckhurst, Ava B Keating, Eileen Moran, Dawn M Bravata
OBJECTIVE: To identify key barriers and facilitators to the delivery of guideline-based care of patients with TIA in the national Veterans Health Administration (VHA). METHODS: We conducted a cross-sectional, observational study of 70 audiotaped interviews of multidisciplinary clinical staff involved in TIA care at 14 VHA hospitals. We de-identified and analyzed all transcribed interviews. We identified emergent themes and patterns of barriers to providing TIA care and of facilitators applied to overcome these barriers...
November 8, 2017: Neurology
https://www.readbyqxmd.com/read/29116361/intermediate-care-units-recommendations-on-facilities-and-structure
#16
REVIEW
C Waydhas, E Herting, S Kluge, A Markewitz, G Marx, E Muhl, T Nicolai, K Notz, V Parvu, M Quintel, E Rickels, D Schneider, K R Steinmeyer-Bauer, G Sybrecht, T Welte
A growing number of patients with increasingly complex or specialized diseases are being treated in hospitals worldwide. The treatment requirements of some of these patients are exceeding the capacity of standard nursing units. However, the severity of these diseases or the treatment requirements for these specific clinical pictures do not always justify admission to an intensive care unit. For this reason, an increasing number of special units (intermediate care units) are being set up to offer highly specialized treatment and close monitoring, in order to fulfil an intermediate role between the standard care unit and the intensive care unit...
November 7, 2017: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://www.readbyqxmd.com/read/29112661/role-of-insurance-coverage-in-contraceptive-use-after-abortion
#17
M Antonia Biggs, Diana Taylor, Ushma D Upadhyay
OBJECTIVE: To assess postaspiration abortion contraceptive use and the role of insurance coverage for abortion in a state that covers abortion and contraception for low-income women. METHODS: This is a secondary analysis of a previously published prospective study to assess the safety of abortion provision. From 2007 through 2013, women seeking first-trimester aspiration abortion were recruited at 25 clinical facilities within four Planned Parenthood affiliates and Kaiser Permanente of Northern California...
November 3, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29110667/a-complex-intervention-to-improve-implementation-of-world-health-organization-guidelines-for-diagnosis-of-severe-illness-in-low-income-settings-a-quasi-experimental-study-from-uganda
#18
Matthew J Cummings, Elijah Goldberg, Savio Mwaka, Olive Kabajaasi, Eric Vittinghoff, Adithya Cattamanchi, Achilles Katamba, Nathan Kenya-Mugisha, Shevin T Jacob, J Lucian Davis
BACKGROUND: To improve management of severely ill hospitalized patients in low-income settings, the World Health Organization (WHO) established a triage tool called "Quick Check" to provide clinicians with a rapid, standardized approach to identify patients with severe illness based on recognition of abnormal vital signs. Despite the availability of these guidelines, recognition of severe illness remains challenged in low-income settings, largely as a result of infrequent vital sign monitoring...
November 6, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/29105728/tests-for-detecting-strabismus-in-children-aged-1-to-6-years-in-the-community
#19
REVIEW
Sarah Hull, Vijay Tailor, Sara Balduzzi, Jugnoo Rahi, Christine Schmucker, Gianni Virgili, Annegret Dahlmann-Noor
BACKGROUND: Strabismus (misalignment of the eyes) is a risk factor for impaired visual development both of visual acuity and of stereopsis. Detection of strabismus in the community by non-expert examiners may be performed using a number of different index tests that include direct measures of misalignment (corneal or fundus reflex tests), or indirect measures such as stereopsis and visual acuity. The reference test to detect strabismus by trained professionals is the cover‒uncover test...
November 6, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29104868/improving-access-to-interventions-among-mothers-screened-positive-for-post-partum-depression-ppd-at-national-programme-on-immunization-npi-clinics-in-south-western-and-south-eastern-nigeria-a-service-development-report
#20
Muideen O Bakare, Mashudat A Bello-Mojeed, Kerim M Munir, Olaniyi O Duduyemi, Andrew O Orovwigho, Odutola I Odetunde, Olufemi G Taiwo, Jushua A Olofinlade, Olakunle N Omotoso, Olayinka H Famurewa, Oladipupo O Omolabi, Adebayo O Jejeloye
We investigate the possibility of improving access to interventions among mothers screened positive for post-partum depression (PPD) at National Programme on Immunization (NPI) clinics randomly selected from Lagos and Enugu States in south-western and south-eastern Nigeria respectively. The principle of human centred design was employed by engaging the mothers screened positive for PPD to be part of the decision making regarding their further assessment and intervention services. The study brought intervention services to primary healthcare centre at the NPI clinics...
2017: Matters
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