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https://www.readbyqxmd.com/read/28919172/comments-on-the-uspstf-draft-recommendation-statement-on-menopausal-hormone-therapy-primary-prevention-of-chronic-conditions
#1
EDITORIAL
Antonio Cano, Margaret Rees, Tommaso Simoncini
No abstract text is available yet for this article.
September 8, 2017: Maturitas
https://www.readbyqxmd.com/read/28919107/combination-of-a%C3%AE-suppression-and-innate-immune-activation-in-the-brain-significantly-attenuates-amyloid-plaque-deposition
#2
Christophe Verbeeck, Anna Carrano, Paramita Chakrabarty, Joanna L Jankowsky, Pritam Das
Anti-Aβ clinical trials are currently underway to determine whether preventing amyloid deposition will be beneficial in arresting progression of Alzheimer disease. Both clinical and pre-clinical studies suggest that anti-amyloid strategies are only effective if started at very early stages of the disease process in a primary prevention strategy. Because this approach will be difficult to deploy, strategies for secondary prevention aimed at later stages of disease are also needed. In this study, we asked whether combining innate immune activation in the brain with concurrent Aβ suppression could enhance plaque clearance and improve pathological outcomes in mice with moderate amyloid pathology...
September 14, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/28918897/colchicine-for-primary-prevention-of-atrial-fibrillation-after-open-heart-surgery-systematic-review-and-meta-analysis
#3
Carsten Lennerz, Manish Barman, Mahmoud Tantawy, Mark Sopher, Peter Whittaker
BACKGROUND: Atrial fibrillation occurs frequently after open-heart surgery. It is associated with increased morbidity and mortality, longer hospital stays, and increased healthcare costs. Prophylactic administration of colchicine may mitigate post-operative atrial fibrillation (POAF). METHODS: We searched PubMed, ClinicalTrials.gov and CENTRAL databases to identify randomized controlled trials (RCTs) that; (1) compared prophylactic use of colchicine to placebo, or usual care, in patients with sinus rhythm who underwent elective open-heart surgery and (2) reported POAF-incidence...
September 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28918428/modification-of-cardiovascular-pharmacotherapy-in-palliative-care-patients-with-cancer-narrative-review
#4
Tomasz Pasierski
Palliative care cancer patients are treated with many drugs especially at the end of life. Limiting of polypharmacy a decreases the risk of associated adverse effects, medical errors and harmful drug interactions The time lag to benefit of many medications used for cardiovascular diseases or risk factors like hypertension, hypercholesterolemia is frequently longer than palliative care cancer patient's life expectancy. It is ethically appropriate to modify, even to discontinue cardiovascular pharmacotherapy when there is no prospect of benefit...
September 13, 2017: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/28917505/association-of-self-reported-discrimination-and-suicide-ideation-in-older-chinese-americans
#5
Lydia W Li, Gilbert C Gee, XinQi Dong
OBJECTIVE: This study examines racial discrimination as a potential novel risk factor for suicide ideation among older Chinese Americans. DESIGN: In a cross-sectional analysis, this study drew on data collected in the Population-based Study of Chinese Elderly in Chicago on Chinese older adults age 60 + in the Greater Chicago area (N = 3,157). Thirty-day suicide ideation was a dichotomous variable, derived from items of the Physical Health Questionnaire and the Geriatric Mental State Examination-Version A...
August 17, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28917393/reduction-in-depressive-symptoms-in-primary-prevention-icd-scheduled-patients-one-year-prospective-study
#6
Revital Amiaz, Elad Asher, Guy Rozen, Efrat Czerniak, Linda Levi, Mark Weiser, Michael Glikson
OBJECTIVE: Implantable Cardioverter Defibrillators (ICDs), have previously been associated with the onset of depression and anxiety. The aim of this one-year prospective study was to evaluate the rate of new onset psychopathological symptoms after elective ICD implantation. METHODS: A total of 158 consecutive outpatients who were scheduled for an elective ICD implantation were diagnosed and screened based on the Mini International Neuropsychiatric Interview (MINI)...
September 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28916221/reduced-risk-of-peanut-sensitization-following-exposure-through-breast-feeding-and-early-peanut-introduction
#7
Tracy J Pitt, Allan B Becker, Moira Chan-Yeung, Edmond S Chan, Wade T A Watson, Rishma Chooniedass, Meghan B Azad
BACKGROUND: Recent trials have shown that avoiding peanuts during infancy increases the risk of peanut allergy; however, these studies did not address maternal peanut consumption. OBJECTIVE: We sought to investigate the relationship between maternal peanut consumption while breast-feeding, timing of direct peanut introduction, and peanut sensitization at age 7 years. METHODS: Secondary analysis of a nested cohort within the 1995 Canadian Asthma Primary Prevention Study intervention study was performed...
August 22, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28915279/first-consensus-on-primary-prevention-and-early-intervention-in-aesthetic-medicine
#8
Marina Landau, Chytra V Anand, Thierry Besins, Yates Yen Yu Chao, Sabrina Guillen Fabi, Uliana Gout, Martina Kerscher, Tatjana Pavicic, Peter Hsien Li Peng, Berthold Rzany, Gerhard Sattler, Tunk Tiryaki, Heidi A Waldorf, Andre Braz
BACKGROUND: Facial aging is a complex interplay of extrinsic and intrinsic factors leading to progressive changes in the skin, subcutaneous tissue, and bone. Clinical experience suggests that early aesthetic intervention may slow the signs of aging, but treatment in the absence of symptoms or with minimal signs of aging has not yet been properly addressed. OBJECTIVES: To provide treatment recommendations for primary prevention and early intervention in individuals with no or minimal signs of aging...
September 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28912716/a-meta-analysis-of-folic-acid-in-combination-with-anti-hypertension-drugs-in-patients-with-hypertension-and-hyperhomocysteinemia
#9
REVIEW
Wen-Wen Wang, Xin-Shi Wang, Zeng-Rui Zhang, Jin-Cai He, Cheng-Long Xie
Folic acid is generally used to lower homocysteine concentrations and prevent stroke and cardiovascular disease (CVD) at present. However, the efficacy of therapies that lower homocysteine concentrations in reducing the risk of CVD and stroke remains controversial. Our objective was to do a meta-analysis of relevant randomized controlled trials (RCTs) to evaluate the efficacy of folic acid supplementation among patients with hypertension and Hyperhomocysteinemia (HT/HHcy). We included RCTs examining the effects of folic acid plus antihypertensive therapy compared to antihypertensive alone...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28912385/-primary-fracture-prevention-through-the-osteoporosis-liaison-service
#10
Shinichi Nakatoh
It is difficult to prevent primary fragility fractures because the subjects have not yet experienced a fracture. The offers of the community Osteoporosis Liaison Service are important for primary prevention of fragility fractures. The prevention, education, enlightenment, and the offer of osteoporosis examinations are included in this service. It is necessary to deliver the prevention services and osteoporosis education according to the age of the subjects. Hence, for young people, it is effective to include in school education that getting high peak bone mass is important, and for the middle-aged population, it is necessary to include education on the maintenance of bone quantity and the impact on risk factors such as smoking and excessive alcohol consumption...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28910945/-nested-case-control-study-on-associated-factors-for-anemia-during-pregnancy
#11
C L Fan, J Y Luo, W J Gong, X Q Liu, S J Zhou, F F Zhang, J Zeng, H X Li, N Feng
Objective: To explore the related factors of anemia during pregnancy and provide scientific evidence for the primary prevention of anemia during pregnancy. Methods: The pregnant women (≤12 pregnant weeks) who received the first pregnancy care in a local medical institution in Hunan province from June 2013 to November 2014 were included in this cohort study, and for them anemia had been excluded by physical examination. Baseline survey and follow up till childbirth were conducted for them. A queue-based nested case-control study (1 ∶ 2) was conducted (380 pregnant women with anemia detected in this study as case group, 760 pregnant women without anemia randomly selected and matched by age, habitual residence during pregnancy as control group...
September 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28910245/trends-in-emergency-department-visits-for-non-traumatic-dental-conditions-in-ontario-from-2006-to-2014
#12
Sonica Singhal, Lindsay McLaren, Carlos Quiñonez
OBJECTIVE: In Canada, non-traumatic dental conditions (NTDCs) presenting in emergency departments (EDs) are dealt with by non-dental professionals who are generally not equipped to deal with such emergencies, resulting in an inefficient usage of heath care resources. This study aimed to assess the burden of ED visits for NTDCs in Ontario by observing trends from 2006 to 2014. METHODS: Aggregate data for Ontario were obtained from the Canadian Institute for Health Information's National Ambulatory Care Reporting System...
September 14, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28905831/primary-prevention-of-ocular-injury-in-agricultural-workers-with-safety-eyewear
#13
Samrat Chatterjee, Deepshikha Agrawal
PURPOSE: The purpose of this study was to determine the effectiveness of preventing eye injury with the use of safety eyewear in agriculture workers. METHODS: A sample group of 575 agricultural workers (Group A) engaged in harvesting paddy were provided with goggles with side covers. Following harvesting, a questionnaire-based survey was carried out to determine the frequency of their eye injuries. Workers with goggles were asked about the duration for which they used the goggles and also list barriers or difficulties with the same...
September 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28903109/does-breastfeeding-shape-food-preferences-links-to-obesity
#14
Alison K Ventura
The first 2 years of life have been recognized as a critical window for obesity prevention efforts. This period is characterized by rapid growth and development and, in a relatively short period of time, a child transitions from a purely milk-based diet to a more varied solid-food diet. Much learning about food and eating occurs during this critical window, and it is well-documented that early feeding and dietary exposures predict later food preferences, eating behaviors, and dietary patterns. The focus of this review will be on the earliest feeding experiences - breast- and formula-feeding - and the unique role of breastfeeding in shaping children's food preferences...
2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28902040/long-term-rifaximin-therapy-as-a-primary-prevention-of-hepatorenal-syndrome
#15
El-Sayed Ibrahim, Ayman Alsebaey, Hassan Zaghla, Sabry Moawad Abdelmageed, Khalid Gameel, Eman Abdelsameea
BACKGROUND: Hepatorenal syndrome (HRS) is a severe complication of liver cirrhosis, with poor survival. Rifaximin is a gut-selective broad-spectrum antibiotic. AIM: The aim of this study was to evaluate the role of rifaximin as a primary prevention of HRS. PATIENTS AND METHODS: Eighty patients with liver cirrhosis and ascites were enrolled. They were randomized into two groups: control (n=40) and rifaximin group (n=40). Baseline liver function tests, renal function tests, complete blood count, international normalized ratio, urine analysis, and abdominal ultrasonography were carried out...
September 8, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28901219/primary-prevention-of-stroke-and-cardiovascular-disease-in-the-community-prevents-methodology-of-a-health-wellness-coaching-intervention-to-reduce-stroke-and-cardiovascular-disease-risk-a-randomized-clinical-trial
#16
Susan Mahon, Rita Krishnamurthi, Alain Vandal, Emma Witt, Suzanne Barker-Collo, Priya Parmar, Alice Theadom, Alan Barber, Bruce Arroll, Elaine Rush, Hinemoa Elder, Jesse Dyer, Valery Feigin
Rationale Stroke is a major cause of death and disability worldwide, yet 80% of strokes can be prevented through modifications of risk factors and lifestyle and by medication. While management strategies for primary stroke prevention in high cardiovascular disease risk individuals are well established, they are underutilized and existing practice of primary stroke prevention are inadequate. Behavioral interventions are emerging as highly promising strategies to improve cardiovascular disease risk factor management...
January 1, 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/28899416/alzheimer-s-disease-prevention-from-risk-factors-to-early-intervention
#17
REVIEW
Marta Crous-Bou, Carolina Minguillón, Nina Gramunt, José Luis Molinuevo
Due to the progressive aging of the population, Alzheimer's disease (AD) is becoming a healthcare burden of epidemic proportions for which there is currently no cure. Disappointing results from clinical trials performed in mild-moderate AD dementia combined with clear epidemiological evidence on AD risk factors are contributing to the development of primary prevention initiatives. In addition, the characterization of the long asymptomatic stage of AD is allowing the development of intervention studies and secondary prevention programmes on asymptomatic at-risk individuals, before substantial irreversible neuronal dysfunction and loss have occurred, an approach that emerges as highly relevant...
September 12, 2017: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/28898523/-yubi-wakka-finger-ring-test-a-practical-self-screening-method-for-sarcopenia-and-a-predictor-of-disability-and-mortality-among-japanese-community-dwelling-older-adults
#18
Tomoki Tanaka, Kyo Takahashi, Masahiro Akishita, Tetsuo Tsuji, Katsuya Iijima
AIM: We developed a simple self-screening method, the "Yubi-wakka (finger-ring)" test to assess sarcopenia swiftly. This prospective cohort study aimed to examine the validity of this test as a practical method among community-dwelling older adults for identifying sarcopenia, and for predicting disability and mortality. METHODS: We followed 1904 older adults, and analyzed associations between this "Yubi-wakka" test result at baseline in 2012 and sarcopenia at baseline, new-onset sarcopenia followed until 2014, and new-certification for the long-term care insurance and mortality followed until 2016...
September 12, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28892133/statins-for-primary-prevention-in-older-adults-an-unresolved-conundrum
#19
EDITORIAL
Michael W Rich, Carl F Pieper
No abstract text is available yet for this article.
September 11, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28892121/statins-for-primary-prevention-of-cardiovascular-events-and-mortality-in-older-men
#20
Ariela R Orkaby, J Michael Gaziano, Luc Djousse, Jane A Driver
BACKGROUND/OBJECTIVES: We sought to determine whether statin use for primary prevention is associated with a lower risk of cardiovascular events or mortality in older men. DESIGN: Prospective cohort study. SETTING: Physicians' Health Study participants. PARTICIPANTS: 7,213 male physicians ≥70 years without a history of cardiovascular disease (CVD). MEASUREMENTS: Multivariable propensity score for statin use with greedy matching (1:1) to minimize confounding by indication...
September 11, 2017: Journal of the American Geriatrics Society
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