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https://www.readbyqxmd.com/read/28089539/reperfusion-therapy-in-patients-with-acute-ischaemic-stroke-caused-by-cervical-artery-dissection
#1
L A Crespo Araico, R Vera Lechuga, A Cruz-Culebras, C Matute Lozano, A de Felipe Mimbrera, P Agüero Rabes, E Viedma Guiard, C Estévez Fraga, J Masjuan Vallejo
INTRODUCTION: Cervical artery dissection (CAD) is responsible for up to 20% of all ischaemic strokes in patients younger than 45. The benefits of acute-phase reperfusion therapy in these patients have yet to be confirmed. METHODS: We conducted a retrospective review of patients with CAD admitted to a comprehensive stroke centre between 2010 and 2015. We recorded baseline clinical characteristics, treatments, functional outcomes, and mortality. RESULTS: We identified 35 cases of CAD (23 carotid/12 vertebral); mean age was 43...
January 12, 2017: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/28000462/asociaci%C3%A3-n-entre-cronotipo-y-obesidad-en-j%C3%A3-venes
#2
Macarena Valladares, Brianda Campos, Camila Zapata, Samuel Durán Agüero, Ana María Obregón
Introducción: existen características respecto a los ritmos circadianos (ciclo sueño-vigilia), lo que genera un rasgo denominado cronotipo (madrugador o trasnochador). Se ha asociado el cronotipo vespertino a menos horas de sueño y hábitos alimentarios poco saludables. El cronotipo vespertino se asocia con un mayor riesgo de desarrollar obesidad.Objetivo: determinar la asociación del cronotipo con variables antropométricas en jóvenes de 18 a 25 años.Métodos: jóvenes (n = 65) (18 a 25 años), se les determinó el cronotipo (cuestionario de Horne-Ostberg) y mediciones antropométricas (peso, talla, porcentaje de grasa y perímetro de cintura)...
November 29, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/27999018/cyclosporine-a-in-addition-to-standard-art-during-primary-hiv-1-infection-pilot-randomized-clinical-trial
#3
David Nicolás, Juan Ambrosioni, Omar Sued, Mercé Brunet, María López-Diéguez, Christian Manzardo, Fernando Agüero, Montserrat Tuset, Montserrat Plana, Alberto C Guardo, María Mar Mosquera, M Ángeles Muñoz-Fernández, Miguel Caballero, M Ángeles Marcos, José M Gatell, Elisa de Lazzari, Teresa Gallart, José M Miró
BACKGROUND: Initiating ART during acute/recent HIV-1 infection reduces viral reservoir formation. It has been proposed that, during this phase, the size of the viral reservoir could be further reduced by the association of immunomodulatory therapy with ART. Contradictory results have emerged, however, from two trials evaluating the impact on immune recovery and the viral reservoir of adding cyclosporine A to ART during primary HIV-1 infection. PATIENTS AND METHODS: Twenty patients with acute/recent HIV-1 infection were randomized to receive ART alone (tenofovir, emtricitabine and lopinavir/ritonavir) or associated with 8 weeks of cyclosporine A (0...
December 20, 2016: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/27975276/mechanisms-of-vertebrate-germ-cell-determination
#4
Tristan Aguero, Susannah Kassmer, Ramiro Alberio, Andrew Johnson, Mary Lou King
Two unique characteristics of the germ line are the ability to persist from generation to generation and to retain full developmental potential while differentiating into gametes. How the germ line is specified that allows it to retain these characteristics within the context of a developing embryo remains unknown and is one focus of current research. Germ cell specification proceeds through one of two basic mechanisms: cell autonomous or inductive. Here, we discuss how germ plasm driven germ cell specification (cell autonomous) occurs in both zebrafish and the frog Xenopus...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27932106/assessment-of-kidney-graft-function-evolution-measured-by-creatinine-and-cystatin-c
#5
M A Ramos-Barron, I Hernandez Bejarano, E Rodrigo, E Cruz Iglesias, A Benito Hernandez, C Agueros Blanco, A I Morales Martin, M Prieto Vicente, F Lopez Hernandez, M Arias, C Gomez-Alamillo
INTRODUCTION: The 2013 Kidney Disease Outcomes Quality Initiative Clinical Practice Guideline suggests measuring cystatin C (sCys) in adults with glomerular filtration rate (GFR) based on creatinine (sCr) between 45 and 59 mL/min/1.73 m(2) if confirmation of chronic kidney disease (CKD) is required. There is not enough evidence to recommend the use of sCys or sCr to estimate GFR in kidney transplant recipients. OBJECTIVES: Our aims were to describe the evolution of sCr, sCys, and GFR in a group of kidney transplant patients and to determine their association with some markers of morbidity at 1 year...
November 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27910061/inhaled-gene-transfer-for-pulmonary-circulation
#6
Jaume Aguero, Lahouaria Hadri, Nadjib Hammoudi, Lauren Leonardson, Roger J Hajjar, Kiyotake Ishikawa
Chronic pulmonary hypertension (PH) is associated with right ventricular failure and high mortality regardless of the underlying disease. Currently, therapies can improve clinical outcomes in specific subsets of patients, but have little impact on the progression of pulmonary vascular remodeling. Upon new advances in vector development and delivery techniques, gene therapy is a novel strategy in this field with the potential of overcoming the main limitations of approved drug therapies: modulation of novel anti-remodeling targets and selective pulmonary vasculature targeting with minimal systemic effects...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27900595/overexpression-of-a-thaumatin-like-protein-gene-from-vitis-amurensis-improves-downy-mildew-resistance-in-vitis-vinifera-grapevine
#7
Rongrong He, Jiao Wu, Yali Zhang, Cecilia B Agüero, Xinlong Li, Shaoli Liu, Chaoxia Wang, M Andrew Walker, Jiang Lu
Downy mildew is a highly destructive disease in grapevine production. A gene encoding pathogenesis-related (PR) thaumatin-like protein was isolated from the downy mildew-resistant grapevine "Zuoshan-1," a clonal selection from wild Vitis amurensis Rupr. The predicted thaumatin-like protein (VaTLP) has 225 amino acids and it is acidic, with a calculated isoelectric point of 4.8. The full length of the VaTLP gene was transformed into somatic embryogenic calli of V. vinifera 'Thompson Seedless' via Agrobacterium tumefaciens...
November 30, 2016: Protoplasma
https://www.readbyqxmd.com/read/27867532/left-ventricular-ejection-fraction-recovery-in-patients-with-heart-failure-treated-with-intravenous-iron-a-pilot-study
#8
Julio Núñez, José Vicente Monmeneu, Anna Mollar, Eduardo Núñez, Vicent Bodí, Gema Miñana, Sergio García-Blas, Enrique Santas, Jaume Agüero, Francisco J Chorro, Juan Sanchis, Maria Pilar López-Lereu
AIMS: In patients with heart failure with reduced ejection fraction (HFrEF) and iron deficiency, treatment with intravenous iron has shown a clinical improvement regardless of anaemic status. Cardiac magnetic resonance (CMR) T2* sequence has shown a potential utility for evaluating myocardial iron deficiency. We aimed to evaluate whether T2* sequence significantly changes after ferric carboximaltose (FCM) administration, and if such changes correlate with changes in left ventricle ejection fraction (LVEF)...
December 2016: ESC Heart Failure
https://www.readbyqxmd.com/read/27807890/impact-of-aspirin-on-trophoblastic-invasion-in-women-with-abnormal-uterine-artery-doppler-at-11%C3%A2-%C3%A2-14-weeks-a-randomized-controlled-study-asap
#9
Elena Scazzocchio, Dani Oros, Daysi Diaz, Juan C Ramirez, Marta Ricart, Eva Meler, Rafael González de Agüero, Eduard Gratacos, Francesc Figueras
BACKGROUND: Defective trophoblastic invasion is a key feature in many of cases of preeclampsia. Uterine artery Doppler is a validated non-invasive surrogate of this trophoblastic invasion. OBJECTIVE: To explore whether low-dose aspirin administered from the first trimester improves trophoblastic invasion, evaluated by uterine Doppler, during the second and third trimesters in women defined as high-risk by abnormal uterine artery Doppler at first trimester. METHODS: This randomized Phase II study had a triple-blind, parallel-arm, controlled design...
November 3, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27786560/varicella-prevention-in-costa-rica-impact-of-a-one-dose-schedule-universal-vaccination
#10
María L Avila-Aguero, Rolando Ulloa-Gutierrez, Kattia Camacho-Badilla, Alejandra Soriano-Fallas, Roberto Arroba-Tijerino, Ana Morice-Trejos
To describe the impact following a 1-dose Varicella vaccination schedule introduced in Costa Rica in September 2007. Areas covered: This is a retrospective review using epidemiologic surveillance national databases of varicella cases and hospitalizations, period 2000-2015. We analyzed age-related varicella incidence cases and hospitalization trends before and after the vaccine introduction. Expert commentary: Varicella vaccine coverage among children 16 months age increased from 76% in 2008 to 95% in 2015...
October 27, 2016: Expert Review of Vaccines
https://www.readbyqxmd.com/read/27765298/fulminant-sepsis-caused-by-clostridium-perfringens
#11
A Guridi Mugica, L Marti Gelonch, R Jimenez Agüero
No abstract text is available yet for this article.
October 17, 2016: Medicina Intensiva
https://www.readbyqxmd.com/read/27736367/association-between-eating-behavior-and-academic-performance-in-university-students
#12
Macarena Valladares, Elizabeth Durán, Alexis Matheus, Samuel Durán-Agüero, Ana María Obregón, Rodrigo Ramírez-Tagle
OBJECTIVE: To determine the association between academic performance and eating behavior in university students in Chile. METHODS: A total of 680 college students, 409 (60%) women and 271 (40%) men, were randomly recruited and the mean age of the entire sample was 26. The Three-Factor Eating Questionnaire (TFEQ), which evaluates 3 dimensions of eating behavior-cognitive restriction (limiting own intake), uncontrolled eating (inclination to eat), and emotional eating (control of food intake in the context of negative emotions)-was used...
November 2016: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/27734352/primordial-germ-cell-isolation-from-xenopus-laevis-embryos
#13
Amanda M Butler, Tristan Aguero, Karen M Newman, Mary Lou King
Primordial germ cells (PGCs) are the precursors to the gametes and have the unique ability to retain full developmental potential. However, the mechanism(s) and gene-network(s) necessary for their proper specification and development are poorly understood. This is due, in part, to the challenges that must be overcome in order to identify and isolate PGCs during critical stages of development. Two distinct mechanisms have been characterized to specify the germ cell lineage in vertebrates: induction and inheritance...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27676509/p1-23-chemotherapy-in-lung-cancer-at-national-institute-of-oncology-at-paraguay-a-retrospective-study-8-years-of-experience-track-advanced-nsclc
#14
Silvia J Ayala Leon, Miguel Agüero Pino, Cinthia Gauna Colás, Maria Rita Pereira, Miguel Ayala Leon
No abstract text is available yet for this article.
October 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27676487/p1-02-lung-cancer-a-previously-years-survival-study-first-statistical-evidence%C3%A2-at-national-institute-of-oncology-in-paraguay-track-prevention-early-detection-epidemiology-and-tobacco-control
#15
Silvia J Ayala Leon, Miguel Agüero Pino, Cinthia Gauna Colás, Maria Rita Pereira, Miguel Ayala Leon
No abstract text is available yet for this article.
October 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27659106/a-rare-presentation-of-gallstones-bouveret%C3%A2-s-syndrome-a-case-report
#16
Lander Gallego Otaegui, Aitor Sainz Lete, Rodrigo David Gutiérrez Ríos, Maialen Alkorta Zuloaga, Xabier Arteaga Martín, Raúl Jiménez Agüero, Miguel Ángel Medrano Gómez, Inmaculada Ruiz Montesinos, Adolfo Beguiristain Gómez
CT images and endoscopic findings in a case of Bouveret's syndrome.
July 2016: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/27647563/detection-of-interleukin-2-is-not-useful-for-distinguishing-between-latent-and-active-tuberculosis-in-clinical-practice-a-prospective-cohort-study
#17
M Santin, F Morandeira-Rego, F Alcaide, R Rabuñal, L Anibarro, R Agüero-Balbín, X Casas-Garcia, E Pérez-Escolano, M D Navarro, F Sánchez, A Coira-Nieto, M Trigo-Daporta, A Martinez-Meñaca, A Gonzalez-Cuevas, M D López-Prieto, A Domínguez-Castellano, N Jové
OBJECTIVE: Previous reports have identified interleukin-2 (IL-2), quantified in the supernatants of QuantiFERON(®)-TB Gold In-tube (QFT) after 72 h of incubation, as a potential biomarker for distinguishing between latent and active tuberculosis (TB). However, its validity has not been tested in an appropriate clinical cohort. METHODS: A multicentre study of 161 consecutive adult patients undergoing evaluation for active TB at eight TB Units in Spain. Interferon-γ (IFN-γ) and IL-2 were assessed in the supernatant of QFT after 16-24 h and 72 h of incubation...
December 2016: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/27640334/identification-and-expressional-analysis-of-nlrc5-inflammasome-gene-in-smolting-atlantic-salmon-salmo-salar
#18
Juan Pablo Pontigo, María José Agüero, Patricio Sánchez, Ricardo Oyarzún, Carolina Vargas-Lagos, Jorge Mancilla, Hans Kossmann, Francisco J Morera, Alejandro J Yáñez, Luis Vargas-Chacoff
The NOD-like receptors (NLRs) were recently identified as an intracellular pathogen recognition receptor family in vertebrates. While the immune system participation of NLRs has been characterized and analyzed in various mammalian models, few studies have considered NLRs in teleost species. Therefore, this study analyzed the Atlantic salmon (Salmo salar) NLRC5. Structurally, Atlantic salmon NLRC5 presented leucine-rich repeat subfamily genes. Phylogenetically, NLRC5 was moderately conserved between S. salar and other species...
November 2016: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/27624569/integrase-strand-transfer-inhibitor-polymorphic-and-accessory-resistance-substitutions-in-patients-with-acute-recent-hiv-infection
#19
J Ambrosioni, D Nicolás, C Manzardo, F Agüero, J L Blanco, M M Mosquera, J Peñafiel, J M Gatell, M A Marcos, J M Miró
OBJECTIVES: The most recent guidelines suggest using integrase strand-transfer inhibitors (InSTIs) as the preferred antiretroviral regimens for naive HIV-infected individuals. However, resistance to InSTIs is not monitored in many centres at baseline. This study aimed to evaluate the prevalence of InSTI resistance substitutions in newly diagnosed patients with acute/recent HIV infection. METHODS: Genotypic drug resistance tests were performed in all consecutive patients prospectively enrolled with a documented infection of <6 months, from 12 May 2015 to 12 May 2016...
January 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/27584289/do-6-months-of-whole-body-vibration-training-improve-bone-mass-acquisition-of-adolescent-swimmers-1133-board-7-june-1-3-15-pm-5-15-pm
#20
German Vicente-Rodríguez, Alejandro Gómez-Bruton, Ángel Matute-Llorente, Cristina Julián-Almarcegui, Gabriel Lozano-Berges, Jorge Marín-Puyalto, Alba Gómez-Cabello, Alejandro González-Agüero, José A Casajús
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
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