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https://www.readbyqxmd.com/read/29756174/phenotypic-detection-of-clinical-isolates-of-haemophilus-influenzae-with-altered-penicillin-binding-protein-3
#1
A Aguirre-Quiñonero, I C Pérez Del Molino, C García de la Fuente, M C Sanjuán, J Agüero, L Martínez-Martínez
The aims of this study were to determine the correlation of mutations in the ftsI gene (coding for PBP3) of Haemophilus influenzae with aminopenicillin resistance and to evaluate the 2017 European Committee for Antibiotic Susceptibility Testing (EUCAST) guidelines for clinical categorization of ampicillin, amoxicillin, and amoxicillin-clavulanate for strains with mutated PBP3 conferring resistance (rPBP3). A panel of 91 H. influenzae isolates was genetically characterized by sequencing of the fstI gene. For all the studied isolates, a screening with benzylpenicillin 1U (BP1) was carried out and minimum inhibitory concentrations (MICs) of ampicillin, amoxicillin, and amoxicillin-clavulanate were tested and interpreted according to EUCAST recommendations...
May 13, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29737414/bone-geometry-in-young-male-and-female-football-players-a-peripheral-quantitative-computed-tomography-pqct-study
#2
Gabriel Lozano-Berges, Ángel Matute-Llorente, Alejandro Gómez-Bruton, Alex González-Agüero, Germán Vicente-Rodríguez, José A Casajús
The present study shows that football practice during growth may improve bone geometry in male and female football players. However, only females had better bone strength in comparison with controls. PURPOSE: The aim of this study was to compare bone geometry in adolescent football players and controls. METHODS: A total of 107 football players (71 males/36 females; mean age 12.7 ± 0.6/12.7 ± 0.6 years) and 42 controls (20 males/22 females; mean age 13...
May 8, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29732254/using-citizen-science-to-bridge-taxonomic-discovery-with-education-and-outreach
#3
Matt von Konrat, Thomas Campbell, Ben Carter, Matthew Greif, Mike Bryson, Juan Larraín, Laura Trouille, Steve Cohen, Eve Gaus, Ayesha Qazi, Eric Ribbens, Tatyana Livshultz, Taylor J Walker, Tomomi Suwa, Taylor Peterson, Yarency Rodriguez, Caitlin Vaughn, Christina Yang, Selma Aburahmeh, Brian Carstensen, Peter de Lange, Charlie Delavoi, Kalman Strauss, Justyna Drag, Blanka Aguero, Chris Snyder, Joann Martinec, Arfon Smith
Premise of the Study: Biological collections are uniquely poised to inform the stewardship of life on Earth in a time of cataclysmic biodiversity loss. Efforts to fully leverage collections are impeded by a lack of trained taxonomists and a lack of interest and engagement by the public. We provide a model of a crowd-sourced data collection project that produces quality taxonomic data sets and empowers citizen scientists through real contributions to science. Entitled MicroPlants, the project is a collaboration between taxonomists, citizen science experts, and teachers and students from universities and K-12...
February 2018: Applications in Plant Sciences
https://www.readbyqxmd.com/read/29724166/surveying-alignment-free-features-for-ortholog-detection-in-related-yeast-proteomes-by-using-supervised-big-data-classifiers
#4
Deborah Galpert, Alberto Fernández, Francisco Herrera, Agostinho Antunes, Reinaldo Molina-Ruiz, Guillermin Agüero-Chapin
BACKGROUND: The development of new ortholog detection algorithms and the improvement of existing ones are of major importance in functional genomics. We have previously introduced a successful supervised pairwise ortholog classification approach implemented in a big data platform that considered several pairwise protein features and the low ortholog pair ratios found between two annotated proteomes (Galpert, D et al., BioMed Research International, 2015). The supervised models were built and tested using a Saccharomycete yeast benchmark dataset proposed by Salichos and Rokas (2011)...
May 3, 2018: BMC Bioinformatics
https://www.readbyqxmd.com/read/29691159/a-cross-sectional-study-of-the-prevalence-of-exercise-induced-hypertension-in-childhood-following-repair-of-coarctation-of-the-aorta
#5
Taryn L Luitingh, Melissa G Y Lee, Bryn Jones, Remi Kowalski, Sofia Weskamp Aguero, Jane Koleff, Diana Zannino, Michael M H Cheung, Yves d'Udekem
BACKGROUND: Exercise-testing may be a more tolerable method of detecting hypertension in children after coarctation repair compared to gold-standard 24-hour ambulatory blood pressure (BP) monitoring (ABPM). This study aims to determine the prevalence of exercise-induced hypertension and end-organ damage in children after coarctation repair, and the effectiveness of exercise-testing compared to 24-hour ABPM in this population. METHODS: Exercise-testing (Bruce protocol), transthoracic echocardiogram, 24-hour ABPM, and pulse wave velocity were performed in 41 patients aged 8 to 18 years with previous coarctation repair...
March 27, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29677480/effect-of-healthy-and-unhealthy-habits-on-obesity-a-multicentric-study
#6
Mirta Crovetto, Macarena Valladares, Valentina Espinoza, Francisco Mena, Gloria Oñate, Macarena Fernandez, Samuel Durán-Agüero
OBJECTIVE: Our aim was to characterize and compare eating patterns of university students in Chile, by sex and body weight, body mass index, and nutritional status. METHODS: This was a cross-sectional study. University students (n = 1454) of Chile were evaluated. A self-assessment survey was used to evaluate healthy eating habits using a questionnaire with values between 1 (do not consume) and 5 (consume) for a total of 9 to 45 points (higher values represent better eating habits)...
February 19, 2018: Nutrition
https://www.readbyqxmd.com/read/29677179/knowledge-of-the-guarani-language-in-medical-students-at-a-university-hospital-in-paraguay
#7
Hassel Jimmy Jiménez, Lorena Delgadillo, Ana Campuzano de Rolon, Diana Jiménez, Angélica de Samudio, Adriana Agüero, César Radice, Gustavo Jiménez-Britez
INTRODUCTION: Paraguay is a bilingual country and knowledge of the guarani language is an important communication tool for the doctor- patient relationship. OBJECTIVE: To determine the degree of and the factors that influence the knowledge of the Guaraní language in medical students at a University Hospital in Paraguay. METHODS: Observational, cross-sectional, analytical study in which an anonymous questionnaire was applied to the final year medical students of a University Hospital of Paraguay...
April 10, 2018: Medwave
https://www.readbyqxmd.com/read/29662529/neoadjuvant-chemotherapy-in-locally-advanced-duodenal-adenocarcinoma
#8
Carlos Velandia, Rafael Delgado Morales, Carlos Coello, Armando Gil Mendoza, Gabriel Pérez, Emperatriz Aguero
Duodenal adenocarcinoma (ADC) represents only 0.3% of gastrointestinal neoplasms. With the frequency being higher between the ages of 40 and 60, it is predominantly located in the second part of the duodenum and around the periampullary region. Symptoms are nonspecific, so the majority of patients present with advanced disease. Neoadjuvant chemotherapy is a therapeutic option that has not been well studied. The global literature includes only isolated reports on this subject. This is why we are presenting the following case: a 60-year-old female patient with a locally advanced, inoperable duodenal ADC received neoadjuvant chemotherapy...
2018: Ecancermedicalscience
https://www.readbyqxmd.com/read/29652973/-febrile-neutropenia-in-cancer-patients-management-in-the-emergency-room
#9
Daniel Rivera-Salgado, Kathia Valverde-Muñoz, María L Ávila-Agüero
Febrile neutropenia is a life-threatening condition that requires immediate attention, especially in patients with chemotherapy-related neutropenia. Patients with febrile neutropenia have a much greater risk of developing bacterial disease, and fever may be the only indicator of severe bacterial infection. Adequate management of febrile neutropenia emphasizes early recognition of patients, risk stratification, and antibiotic therapy administration during the first 60 minutes of admission to an emergency room...
2018: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/29626614/effects-of-whole-body-vibration-on-tibia-strength-and-structure-of-competitive-adolescent-swimmers-a-randomized-controlled-trial
#10
Alejandro Gómez-Bruton, Alejandro González-Agüero, Angel Matute-Llorente, Cristina Julián, Gabriel Lozano-Berges, Alba Gómez-Cabello, Nuria Garatachea, Jose A Casajús, German Vicente-Rodríguez
BACKGROUND: Swimming has no effect on bone mass or structure. Therefore, adolescent swimmers present similar bone strength values when compared to normo-active controls, and lower values when compared to weight-bearing athletes. It thus seems necessary to try to improve bone structure and strength of adolescent swimmers through a weight-bearing intervention in order to reduce the risk of suffering osteoporosis later in life. OBJECTIVE: To evaluate the effects of a 6-month WBV intervention on bone strength and structure of adolescent swimmers...
April 4, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29606127/stand-by-emergency-treatment-sbet-of-malaria-in-spanish-travellers-a-cohort-study
#11
Pietro Ferrara, Cristina Masuet-Aumatell, Fernando Agüero, Josep Maria Ramon-Torrell
BACKGROUND: Among strategies for malaria prevention, stand-by emergency treatment (SBET) is a possible approach, but scarce evidences exists investigating travellers' adherence and behaviours toward its use; therefore, the presented study aimed to determine travellers' compliance toward the SBET when prescribed in travel clinics. METHODS: A prospective cohort study was performed at the Travel Health Clinic of the Hospital Universitari de Bellvitge, Barcelona, Spain, during 2017...
April 2, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29605357/obstructive-sleep-apnea-syndrome-and-growth-failure
#12
E Esteller, J C Villatoro, A Agüero, R Lopez, E Matiñó, J Argemi, M Girabent-Farrés
Obstructive sleep apnea syndrome is a common problem among children and is recognized as a cause of significant medical morbidity. Since the 1980s, it has been suggested that obstructive sleep apnea syndrome is a risk factor for growth failure in children. In many cases, it has been shown that growth failure is reversible once the obstructive sleep apnea syndrome is resolved. The objectives of this study were to analyze and compare growth failure prevalence in a Mediterranean population of children with obstructive sleep apnea syndrome and healthy children matched in age and sex, and to assess the effectiveness of tonsillectomy and adenoidectomy in resolving growth retardation...
May 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29557597/pain-in-adolescents-and-its-risk-factors-a-case-control-study
#13
Gonzalo Agüero, Soledad Salmain, Belén Manzur, Enrique Berner
INTRODUCTION: The most common painful syndromes (headache, abdominal pain and musculoskeletal pain) develop or worsen during adolescence and are a common reason for consultation. OBJECTIVE: Evaluate the association of age, sex, obesity, pubertal development, schooling level, employment and family structure with consultation for pain in adolescents. POPULATION AND METHODS: Case-control study conducted between February 1st, 2014 and June 30th, 2015...
April 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29546070/d-tagatose-is-a-promising-sweetener-to-control-glycaemia-a-new-functional-food
#14
REVIEW
Marion Guerrero-Wyss, Samuel Durán Agüero, Lisse Angarita Dávila
The objective of the current research was to review and update evidence on the dietary effect of the consumption of tagatose in type 2 diabetes, as well as to elucidate the current approach that exists on its production and biotechnological utility in functional food for diabetics. Articles published before July 1, 2017, were included in the databases PubMed, EBSCO, Google Scholar, and Scielo, including the terms "Tagatose", "Sweeteners", "Diabetes Mellitus type 2", "Sweeteners", "D-Tag"...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29514806/left-ventricular-unloading-using-an-impella-cp-improves-coronary-flow-and-infarct-zone-perfusion-in-ischemic-heart-failure
#15
Shin Watanabe, Kenneth Fish, Jason C Kovacic, Olympia Bikou, Lauren Leonardson, Koichi Nomoto, Jaume Aguero, Navin K Kapur, Roger J Hajjar, Kiyotake Ishikawa
BACKGROUND: Delivering therapeutic materials, like stem cells or gene vectors, to the myocardium is difficult in the setting of ischemic heart failure because of decreased coronary flow and impaired microvascular perfusion (MP). The aim of this study was to determine if mechanical left ventricular (LV) unloading with the Impella increases coronary flow and MP in a subacute myocardial infarction. METHODS AND RESULTS: Anterior transmural myocardial infarction (infarct size, 26...
March 7, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29511682/noncaloric-sweeteners-in-children-a-controversial-theme
#16
REVIEW
Samuel Durán Agüero, Lissé Angarita Dávila, Ma Cristina Escobar Contreras, Diana Rojas Gómez, Jorge de Assis Costa
Noncaloric sweeteners (NCS) are food additives used to provide sweetness without adding calories. Their consumption has become more widespread around the world in all age groups, including children. The aim of this study is to show the state of the art about the intake of noncaloric sweeteners in children, as well as their benefits and consumption risk. Scientific searchers were used (PUBMED, Scopus, and Scielo) to analyze articles that included keywords (noncaloric sweeteners/saccharin/cyclamate/acesulfame potassium/aspartame/sucralose/stevia/children) in English, Spanish, and Portuguese...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29503124/the-immunological-functions-of-the-appendix-an-example-of-redundancy
#17
REVIEW
Mathilde J H Girard-Madoux, Mercedes Gomez de Agüero, Stephanie C Ganal-Vonarburg, Catherine Mooser, Gabrielle T Belz, Andrew J Macpherson, Eric Vivier
Biological redundancy ensures robustness in living organisms at several levels, from genes to organs. In this review, we explore the concept of redundancy and robustness through an analysis of the caecal appendix, an organ that is often considered to be a redundant remnant of evolution. However, phylogenic data show that the Appendix was selected during evolution and is unlikely to disappear once it appeared. In humans, it is highly conserved and malformations are extremely rare, suggesting a role for that structure...
April 2018: Seminars in Immunology
https://www.readbyqxmd.com/read/29499433/exogenous-gibberellic-acid-application-induces-the-overexpression-of-key-genes-for-pedicel-lignification-and-an-increase-in-berry-drop-in-table-grape
#18
Miguel García-Rojas, Marco Meneses, Kristen Oviedo, Carlos Carrasco, Bruno Defilippi, Mauricio González-Agüero, Gabriel León, Patricio Hinrichsen
Most table grape (Vitis vinifera L.) varieties require gibberellic acid (GA3 ) applications to obtain an adequate berry size in order to satisfy market requirements. However, GA3 treatments also produce severe berry drop in some cultivars, which occurs mainly after a cold storage period during post-harvest. Berry drop in bunches treated with GA3 has been related to the hardening and thickening of the pedicel produced by the over-accumulation of cellulose and its lignification. The main goal of this study was to compare the morphology and gene expression in pedicel samples of genotypes contrasting for berry drop susceptibility...
May 2018: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/29481946/human-serum-albumin-nanoparticles-for-ocular-delivery-of-bevacizumab
#19
Inés Luis de Redín, Carolina Boiero, María Cristina Martínez-Ohárriz, Maite Agüeros, Rocío Ramos, Iván Peñuelas, Daniel Allemandi, Juan M Llabot, Juan M Irache
Bevacizumab-loaded nanoparticles (B-NP) were prepared by a desolvation process followed by freeze-drying, without any chemical, physical or enzymatic cross-linkage. Compared with typical HSA nanoparticles cross-linked with glutaraldehyde (B-NP-GLU), B-NP displayed a significantly higher mean size (310 nm vs. 180 nm) and a lower negative zeta potential (-15 mV vs. -36 mV). On the contrary, B-NP displayed a high payload of approximately 13% when measured by a specific ELISA, whereas B-NP-GLU presented a very low bevacizumab loading (0...
April 25, 2018: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29476876/changes-and-clinical-consequences-of-smoking-cessation-in-patients-with-copd-a-prospective-analysis-from-the-chain-cohort
#20
Cristina Martínez-González, Ciro Casanova, Juan P de-Torres, José M Marín, Pilar de Lucas, Antonia Fuster, Borja G Cosío, Myriam Calle, Germán Peces-Barba, Ingrid Solanes, Ramón Agüero, Nuria Feu-Collado, Inmaculada Alfageme, Amparo Romero Plaza, Eva Balcells, Alfredo de Diego, Margarita Marín Royo, Amalia Moreno, Antonia Llunell Casanovas, Juan B Galdiz, Rafael Golpe, Celia Lacárcel Bautista, Carlos Cabrera, Alicia Marin, Joan B Soriano, Jose Luis Lopez-Campos
BACKGROUND: Despite the existing evidence-based smoking cessation interventions, chances of achieving that goal in real life are still low among patients with COPD. We sought to evaluate the clinical consequences of changes in smoking habits in a large cohort of patients with COPD. METHODS: CHAIN (COPD History Assessment in Spain) is a Spanish multicenter study carried out at pulmonary clinics including active and former smokers with COPD. Smoking status was certified by clinical history and co-oximetry...
February 22, 2018: Chest
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