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https://www.readbyqxmd.com/read/28555597/hyperbaric-oxygen-therapy-as-salvage-therapy-for-sudden-sensorineural-hearing-loss
#1
Jakov Ajduk, Mihael Ries, Robert Trotic, Ivana Marinac, Kovacic Vlatka, Vladimir Bedekovic
OBJECTIVE: To measure the effect of hyperbaric oxygen (HBO) therapy as salvage therapy after the failure of steroid therapy for sudden sensorineural hearing loss (SSNHL). MATERIALS AND METHODS: Ninety-three patients with SSNHL were unsuccessfully treated with systemic steroid therapy. Following steroid therapy, 43 patients received additional HBO therapy while 50 did not. Hearing levels at 0.25, 0.5, 1, 2, 4, and 8 kHz before and after therapy were measured. RESULTS: A significant difference in hearing thresholds after HBO therapy was found at all frequencies in patients with a hearing loss of >61 dB...
April 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28394652/nationwide-epidemiological-survey-of-idiopathic-sudden-sensorineural-hearing-loss-in-japan
#2
Ryosuke Kitoh, Shin-Ya Nishio, Kaoru Ogawa, Sho Kanzaki, Naohito Hato, Michihiko Sone, Satoshi Fukuda, Akira Hara, Tetsuo Ikezono, Kotaro Ishikawa, Satoshi Iwasaki, Kimitaka Kaga, Seiji Kakehata, Atsushi Matsubara, Tatsuo Matsunaga, Takaaki Murata, Yasushi Naito, Takashi Nakagawa, Kazunori Nishizaki, Yoshihiro Noguchi, Hajime Sano, Hiroaki Sato, Mikio Suzuki, Hideo Shojaku, Haruo Takahashi, Hidehiko Takeda, Testuya Tono, Hiroshi Yamashita, Tatsuya Yamasoba, Shin-Ichi Usami
OBJECTIVES: Using a large-scale nationwide survey database, we investigated the epidemiological characteristics for idiopathic SSNHL in Japan. METHODS: The subjects for this analysis were patients registered in a Japanese multicentre database between April 2014 and March 2016. A total of 3419 idiopathic SSNHL patients were registered in the database, and the clinical characteristics of the idiopathic SSNHL patients were obtained. Several factors associated with the severity of hearing impairment and prognosis were then investigated...
2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28384627/simultaneous-versus-sequential-intratympanic-steroid-treatment-for-severe-to-profound-sudden-sensorineural-hearing-loss
#3
Myung Hoon Yoo, Won Sub Lim, Joo Hyun Park, Joong Keun Kwon, Tae-Hoon Lee, Yong-Hwi An, Young-Jin Kim, Jong Yang Kim, Hyun Woo Lim, Hong Ju Park
OBJECTIVES: Severe-to-profound sudden sensorineural hearing loss (SSNHL) has a poor prognosis. We aimed to compare the efficacy of simultaneous and sequential oral and intratympanic steroids for this condition. METHODS: Fifty patients with severe-to-profound SSNHL (>70 dB HL) were included from 7 centers. The simultaneous group (27 patients) received oral and intratympanic steroid injections for 2 weeks. The sequential group (23 patients) was treated with oral steroids for 2 weeks and intratympanic steroids for the subsequent 2 weeks...
2016: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28384326/increased-risk-of-sudden-sensorineural-hearing-loss-in-patients-with-hepatitis-virus-infection
#4
Hsin-Chien Chen, Chi-Hsiang Chung, Chih-Hung Wang, Jung-Chun Lin, Wei-Kuo Chang, Fu-Huang Lin, Chang-Huei Tsao, Yung-Fu Wu, Wu-Chien Chien
The etiology of sudden sensorineural hearing loss (SSNHL) remains unclear. Possible causes of SSNHL include vascular diseases, viral infection, and autoimmune disorders. Therefore, we investigated whether hepatitis virus infection is correlated with the risk of SSNHL. Using data from the Taiwan Longitudinal Health Insurance Database, we conducted a retrospective matched-cohort study to compare patients diagnosed with hepatitis B or C virus (HBV/HCV) infections from January 1, 2000, to December 31, 2010, (N = 170,942) with frequency-matched controls (N = 512,826) at a ratio of 1:3 by sex, age, and index year...
2017: PloS One
https://www.readbyqxmd.com/read/28366083/idiopathic-sudden-sensorineural-hearing-loss-and-acute-low-tone-sensorineural-hearing-loss-a-comparison-of-the-results-of-a-nationwide-epidemiological-survey-in-japan
#5
Tadao Yoshida, Michihiko Sone, Ryosuke Kitoh, Shin-Ya Nishio, Kaoru Ogawa, Sho Kanzaki, Naohito Hato, Satoshi Fukuda, Akira Hara, Tetsuo Ikezono, Kotaro Ishikawa, Satoshi Iwasaki, Kimitaka Kaga, Seiji Kakehata, Atsushi Matsubara, Tatsuo Matsunaga, Takaaki Murata, Yasushi Naito, Takashi Nakagawa, Kazunori Nishizaki, Yoshihiro Noguchi, Hajime Sano, Hiroaki Sato, Mikio Suzuki, Hideo Shojaku, Haruo Takahashi, Hidehiko Takeda, Testuya Tono, Hiroshi Yamashita, Tatsuya Yamasoba, Shin-Ichi Usami
OBJECTIVES: The aim of this study was to investigate the differences between idiopathic sudden sensorineural hearing loss (SSNHL), and acute low-tone sensorineural hearing loss (ALHL) using the results of a nationwide survey database in Japan and to analyze the variables associated with their clinical features and the severity of hearing impairment, treatment, and prognosis. METHODS: Participants were patients registered between April 2014 and March 2016 in a multicenter epidemiological survey database involving 30 university hospitals and medical centers across Japan...
2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28366076/relationships-among-drinking-and-smoking-habits-history-of-diseases-body-mass-index-and-idiopathic-sudden-sensorineural-hearing-loss-in-japanese-patients
#6
Mitsumasa Umesawa, Gen Kobashi, Ryoshuke Kitoh, Shin-Ya Nishio, Kaoru Ogawa, Naohito Hato, Michihiko Sone, Satoshi Fukuda, Akira Hara, Tetsuo Ikezono, Kotaro Ishikawa, Satoshi Iwasaki, Kimitaka Kaga, Seiji Kakehata, Atsushi Matsubara, Tatsuo Matsunaga, Takaaki Murata, Yasushi Naito, Takashi Nakagawa, Kazunori Nishizaki, Yoshihiro Noguchi, Hajime Sano, Hiroaki Sato, Mikio Suzuki, Hideo Shojaku, Haruo Takahashi, Hidehiko Takeda, Tetsuya Tono, Hiroshi Yamashita, Tatsuya Yamasoba, Shin-Ichi Usami
OBJECTIVES: To present the cardiovascular risk factors in idiopathic sudden sensorineural hearing loss (SSNHL) patients enrolled in a nationwide epidemiological survey of hearing disorders in Japan. MATERIALS AND METHODS: We compiled the cardiovascular risk factors in 3073 idiopathic SSNHL subjects (1621 men and 1452 women) and compared their proportions with controls as part of the National Health and Nutrition Survey in Japan, 2014. The cardiovascular risk factors consisted of drinking and smoking habits, a history of five conditions related to cardiovascular disease and body mass index...
2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28366034/prognostic-impact-of-gene-polymorphisms-in-patients-with-idiopathic-sudden-sensorineural-hearing-loss
#7
Ryosuke Kitoh, Shin-Ya Nishio, Shin-Ichi Usami
OBJECTIVE: To investigate whether genetic polymorphisms (single-nucleotide polymorphism [SNPs]) have a prognostic influence on hearing recovery after standardized corticosteroid therapy. METHODS: A total of 192 gene samples from idiopathic sudden sensorineural hearing loss (SSNHL) patients registered in the Intractable Inner Ear Disease Gene Bank were enrolled and, as the candidate genes, 16 SNPs from 13 genes were selected for this study. Fischer's exact test was used to compare allele frequencies in each SNP between the patients with good hearing recovery and patients with poor hearing recovery...
2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28359220/the-effect-of-initial-treatment-on-hearing-prognosis-in-idiopathic-sudden-sensorineural-hearing-loss-a-nationwide-survey-in-japan
#8
Masahiro Okada, Naohito Hato, Shin-Ya Nishio, Ryosuke Kitoh, Kaoru Ogawa, Sho Kanzaki, Michihiko Sone, Satoshi Fukuda, Akira Hara, Tetsuo Ikezono, Kotaro Ishikawa, Satoshi Iwasaki, Kimitaka Kaga, Seiji Kakehata, Atsushi Matsubara, Tatsuo Matsunaga, Takaaki Murata, Yasushi Naito, Takashi Nakagawa, Kazunori Nishizaki, Yoshihiro Noguchi, Hajime Sano, Hiroaki Sato, Mikio Suzuki, Hideo Shojaku, Haruo Takahashi, Hidehiko Takeda, Tetsuya Tono, Hiroshi Yamashita, Tatsuya Yamasoba, Shin-Ichi Usami
OBJECTIVE: To investigate the hearing prognosis of idiopathic sudden sensorineural hearing loss (SSNHL) treated with different initial therapies. METHODS: Subjects consisted of patients diagnosed with idiopathic SSNHL within 7 days from onset and showing severe hearing loss (≥60 dB), who were registered in a Japanese multicenter database between April 2014 and March 2016. Subjects were divided into four groups according to initial therapy: (1) steroids, (2) steroids + Prostaglandins (PGs), (3) intratympanic steroids (ITS), and (4) no steroids...
2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28207624/combined-intratympanic-and-systemic-use-of-steroids-as-a-first-line-treatment-for-sudden-sensorineural-hearing-loss-a-meta-analysis-of-randomized-controlled-trials
#9
Xue Han, Xiao Yin, Xiaodong Du, Changling Sun
OBJECTIVE: To compare the efficacy of combination therapy (combined intratympanic and systemic use of steroids, CT) with systemic steroid therapy (SST) as a primary treatment for sudden sensorineural hearing loss (SSNHL). METHODS: An electronic database search (PubMed, Embase, Cochrane Library, and CNKI databases) was performed. Review Manger 5.3 was used for data synthesis. Data were collected on the following outcomes of interest: the proportion of patients with hearing improvement, changes in pure tone averages (PTA), and speech discrimination score (SDS)...
April 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28163314/a-narrative-review-of-obesity-and-hearing-loss
#10
REVIEW
N Dhanda, S Taheri
The comorbidities related to obesity are already extensive, but as the prevalence of obesity increases globally, so do the number of its associated conditions. The relationship between hearing impairment and obesity is a relatively recent research interest, but is significant as both conditions have the ability to substantially reduce an individual's quality of life both physically and psychologically. Obesity has a significant effect on vascular function, and this may have an impact on highly vascular organs such as the auditory system...
February 28, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/27964845/intratympanic-steroid-injection-and-hyperbaric-oxygen-therapy-for-the-treatment-of-refractory-sudden-hearing-loss
#11
Filiz Gülüstan, Zahide Mine Yazıcı, Wesam M E Alakhras, Omer Erdur, Harun Acipayam, Levent Kufeciler, Fatma Tulin Kayhan
INTRODUCTION: Controversy surrounds the use of salvage therapies to treat sudden sensorineural hearing loss (SSNHL), with no consensus on recommendations. While several studies have demonstrated the effectiveness of intratympanic administration of steroids (ITS) and hyperbaric oxygen (HBO) treatment, few have compared the efficacy of ITS and HBO therapy in patients with refractory SSNHL. OBJECTIVE: We evaluated the efficiency of ITS and HBO therapy in patients with refractory SSNHL...
November 22, 2016: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/27895287/sudden-sensorineural-hearing-loss-is-there-a-connection-with-inner-ear-electrolytic-disorders-a-literature-review
#12
REVIEW
Andrea Ciorba, Virginia Corazzi, Chiara Bianchini, Claudia Aimoni, Henryk Skarzynski, Piotr Henryk Skarzynski, Stavros Hatzopoulos
Electrolytic disorders of the inner ear represent a model that could be implicated in partially explaining the pathogenesis of sudden sensorineural hearing loss (SSNHL). Different types of electrolytes and different inner-ear loci are involved in cochlear homeostasis physiologically, to ensure the maintenance of an ion-balanced cochlear environment allowing a normal hair cell function. It has been hypothesized that a sudden loss of endocochlear potential, due to a rapid disruption of the inner ear fluid osmolality, could be responsible for a deterioration of the hearing function caused by damaged hair cells...
December 2016: International Journal of Immunopathology and Pharmacology
https://www.readbyqxmd.com/read/27861924/intratympanic-dexamethasone-in-sudden-sensorineural-hearing-loss-a-systematic-review-and-meta-analysis
#13
REVIEW
Nagi G El Sabbagh, Maida J Sewitch, Aren Bezdjian, Sam J Daniel
OBJECTIVE: Systemic dexamethasone has demonstrated conclusive benefits in reversing sudden sensorineural hearing loss (SSNHL) despite considerable number of potential side effects. In contrast, the intratympanic route of steroid administration averts several possible complications. This study aims to examine the literature to delineate the efficacy and side effect of intratympanic dexamethasone (ITD) injection for the treatment of SSNHL. DATA SOURCE: Cochrane, Embase, and MEDLINE electronic databases from January 1950 to August 2014, with an update performed on November 10, 2014...
November 15, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27804864/immunology-rheumatology-approach-to-sudden-sensorineural-hearing-loss
#14
Mohsen Rajati, Massod Saghafi, Houshang Rafatpanah, Bashir Rasoulian, Shirin Irani, Mohammadsaleh Soltankhah
BACKGROUND: Sensorineural hearing loss (SNHL) and vestibular dysfunction have been described in various autoimmune disorders and systemic vasculitides. A high prevalence of SNHL is reported to occur in established rheumatologic diseases; however, immunologic and rheumatologic disorders make up a small proportion of patients with sudden sensorineural hearing loss (SSNHL). OBJECTIVE: This prospective study was carried out in order to determine the prevalence of rheumatologic and immunologic disorders in patients with SSNHL in Northeast Iran...
October 29, 2016: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/27712131/sudden-sensorineural-hearing-loss-is-there-a-relationship-between-routine-haematological-parameters-and-audiogram-shapes
#15
Pietro Salvago, Serena Rizzo, Antonino Bianco, Francesco Martines
OBJECTIVE: To investigate the relationship between haematological routine parameters and audiogram shapes in patients affected by sudden sensorineural hearing loss (SSNHL). DESIGN: A retrospective study. All patients were divided into four groups according to the audiometric curve and mean values of haematological parameters (haemoglobin, white blood cell, neutrophils and lymphocytes relative count, platelet count, haematocrit, prothrombin time, activated partial thromboplastin time, fibrinogen and neutrophil-to-lymphocite ratio) of each group were statistically compared...
October 7, 2016: International Journal of Audiology
https://www.readbyqxmd.com/read/27666709/-analysis-of-the-relevant-factors-for-recurrent-sudden-sensorineural-hearing-loss
#16
H Liang, S X Zhong
Objective: To investigate the possible factors related to recurrence and prognosis of sudden sensorineural hearing loss(SSNHL). Methods: Four hundred and ninety-five patients with unilateral sudden sensorineural hearing loss between January 2013 to April 2014 were analyzed retrospectively(34 patients lost to follow-up with a dropout rate of 6.87%). Twenty of the 495 patients were diagnosed as recurrent SSNHL and treated again in the same hospital. The data of the patients were summarized to analyze the related factors which might influence the recurrence and prognosis of SSNHL...
September 7, 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/27631827/clinical-implication-of-the-threshold-equalizing-noise-test-in-patients-with-sudden-sensorineural-hearing-loss
#17
Ji Eun Choi, Jung Joo Lee, Won-Ho Chung, Yang-Sun Cho, Sung Hwa Hong, Il Joon Moon
OBJECTIVE: The aims of the present study were to investigate the prevalence of cochlear dead regions (DRs) in patients with sudden sensorineural hearing loss (SSNHL) and compare the hearing outcome according to the presence of DRs. STUDY DESIGN: Retrospective chart review. SETTING: Tertiary referral center. PATIENTS AND METHODS: The threshold-equalizing noise (HL) test was performed on a total of 112 ears diagnosed with SSNHL...
September 14, 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27603402/risk-of-sudden-sensorineural-hearing-loss-in-stroke-patients-a-5-year-nationwide-investigation-of-44-460-patients
#18
Chin-Lung Kuo, An-Suey Shiao, Shuu-Jiun Wang, Wei-Pin Chang, Yung-Yang Lin
Poststroke sudden sensorineural hearing loss (SSNHL) can hinder communication between patients and healthcare professionals, thereby restricting participation in rehabilitation programs and limiting improvements in physical performance. However, the relationship between stroke and SSNHL remains unclear. This study employed a nationwide population-based dataset to investigate the relationship between stroke and SSNHL.The Taiwan Longitudinal Health Insurance Database was used to compile data from 11,115 stroke patients and a comparison cohort of 33,345 matched nonstroke enrollees...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27598228/the-neutrophil-to-lymphocyte-ratio-in-children-with-sudden-sensorineural-hearing-loss-a-retrospective-study
#19
Joong Seob Lee, Sung Kwang Hong, Dong Hyun Kim, Ju Han Lee, Hyo-Jeong Lee, Bumjung Park, Hyo Geun Choi, Il Gyu Kong, Hong Ji Song, Hyung-Jong Kim
CONCLUSION: The elevated neutrophil-to-lymphocyte ratio (NLR) value in children with sudden sensorineural hearing loss (SSNHL) would suggest the inflammatory etiology of pediatric SSNHL. The results of this study may suggest NLR value can be used as a useful indicator, which is associated with the disease severity in pediatric SSNHL. OBJECTIVES: This study aimed to elucidate any clues of inflammatory etiology, which might be related with the development of pediatric SSNHL, using calculated NLR...
January 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/27497416/pediatric-sudden-sensorineural-hearing-loss-etiology-diagnosis-and-treatment-in-20-children
#20
Kavita Dedhia, David H Chi
OBJECTIVES: 1. To report our experience in children with sudden-onset sensorineural hearing loss (SSNHL). 2. To describe the etiology and management of children with SSNHL. METHODS: Retrospective review of 20 children with SSNHL, from 2000 to 2013 at a tertiary pediatric facility. Patients had the following inclusion criteria: history of normal hearing, hearing loss occurring in less than 3 days, and audiogram documentation. RESULTS: The average age of patients presenting with SSNHL is 11 years 3 months (22months-18years)...
September 2016: International Journal of Pediatric Otorhinolaryngology
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