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https://www.readbyqxmd.com/read/29145284/effectiveness-of-bariatric-surgical-procedures-a-systematic-review-and-network-meta-analysis-of-randomized-controlled-trials
#1
Jenny H Kang, Quang A Le
BACKGROUND: Bariatric surgery has proved to be an effective strategy in treating obesity. However, randomized controlled trials (RCTs) of 3 most common bariatric surgery procedures, Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy (SG), and laparoscopic adjustable gastric band (LAGB), reported inconsistent results. We performed a systematic review and network meta-analysis to synthesize evidence of effectiveness of the 3 common bariatric procedures from relevant RCTs. METHODS: The present study was a systematic review and network meta-analysis of RCTs...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29144812/increased-bone-turnover-in-type-2-diabetes-patients-randomized-to-bariatric-surgery-vs-medical-therapy-at-5-years
#2
Megan R Crawford, Nathan Pham, Leila Khan, James F Bena, Philip R Schauer, Sangeeta R Kashyap
OBJECTIVE: The aim of our study was to determine the 5 year outcomes of bariatric surgery vs. intensive medical therapy on bone turnover in patients with type 2 diabetes (T2DM) from the STAMPEDE trial. METHODS: This is an ancillary investigation of a 5 year randomized control trial at a single tertiary care center involving 95 patients aged 48.5 ± 8 years with obesity (BMI: 36.5±3.6 kg/m(2)) and uncontrolled T2DM (HbA1C: 9.3 ±1.6%). Patients were randomized to intensive medical therapy (IMT; N=25), Roux-en-Y gastric bypass (RYGB; N=37), or sleeve gastrectomy (SG; N=33) for diabetes treatment...
November 16, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/29135972/roux-en-y-gastric-bypass-reduces-plasma-cholesterol-in-diet-induced-obese-mice-by-affecting-trans-intestinal-cholesterol-excretion-and-intestinal-cholesterol-absorption
#3
C Blanchard, F Moreau, A Ayer, L Toque, D Garçon, L Arnaud, F Borel, A Aguesse, M Croyal, M Krempf, X Prieur, M Neunlist, B Cariou, C Le May
OBJECTIVE: Bariatric surgery appears as the most efficient therapeutic alternative in morbidly obese patients. In addition to its efficiency to decrease body weight, it also improves metabolic complications associated to morbid obesity, including dyslipidemia. Although the cholesterol-lowering effect varies with the bariatric procedures, the underlying molecular mechanisms remain poorly defined. This study aims to assess the consequence of both restrictive (sleeve gastrectomy; SG) and malabsorptive (Roux-en-Y gastric bypass; RYGB) procedures on cholesterol metabolism in mice...
September 28, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29135892/-lower-body-lift-in-the-massive-weight-loss-patient-a-new-classification-and-algorithm-for-gluteal-augmentation
#4
Taliah Schmitt, Samer Jabbour, Rani Makhoul, Warren Noel, Anne-Sophie Reguesse, Philippe Levan
BACKGROUND: An often neglected part of the lower body lift procedure is the gluteal region. The objective of this study is to classify the massive weight loss (MWL) patients undergoing a body lift procedure and provide a safe, standardized approach for gluteal augmentation. METHODS: A retrospective review of all body lift procedures performed between January 2012 and January 2017 was conducted. Patients undergoing a lower body lift with or without gluteal augmentation were included for analysis...
November 8, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29127578/comparative-outcomes-of-bariatric-surgery-in-patients-with-and-without-human-immunodeficiency-virus
#5
Gautam Sharma, Andrew T Strong, Mena Boules, Chao Tu, Samuel Szomstein, Raul Rosenthal, John Rodriguez, Alan J Taege, Matthew Kroh
BACKGROUND: Paradoxically, advances in anti-retroviral therapy that has increased survival for patients with human immunodeficiency virus (HIV) have resulted in greater numbers of HIV+ patients developing other chronic diseases, including obesity. Little comparative literature exists detailing perioperative or metabolic outcomes of bariatric surgery in the HIV+ population compared to HIV negative (HIV-) controls. METHODS: This is a retrospective case-control study with both HIV+ (case) and HIV- control patients...
November 10, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29122527/implementation-of-enhanced-recovery-programs-for-bariatric-surgery-results-from-the-francophone-large-scale-database
#6
Anissa Deneuvy, Karem Slim, Maxime Sodji, Pierre Blanc, Denis Gallet, Marie-Cécile Blanchet
BACKGROUND: The feasibility, safety, and efficacy of programs for enhanced recovery after bariatric surgery (ERABS) are now well established. However, data concerning their large-scale implementation remain insufficient. OBJECTIVES: The objective of the present study was to review the multicenter implementation of ERABS SETTING: This retrospective analysis of a prospective database was conducted in 15 Groupe francophone de Rehabilitation Améliorée après ChirurgiE centers from data from March 2014 to January 2017...
October 4, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29120924/potential-mechanisms-underlying-the-effect-of-bariatric-surgery-on-eating-behaviour
#7
Roxanna Zakeri, Rachel L Batterham
PURPOSE OF REVIEW: Reduced energy intake, resulting from favourable changes in eating behaviour, is the predominant driver of weight loss following bariatric surgery. Here we review the most recent studies examining the impact of Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy, the two most common bariatric procedures, upon eating behaviour and the suggested underlying biological mechanisms. RECENT FINDINGS: Following RYGB or sleeve gastrectomy, most people report subjective changes in appetite, taste and food preference, with decreased high-fat preference most commonly reported...
November 7, 2017: Current Opinion in Endocrinology, Diabetes, and Obesity
https://www.readbyqxmd.com/read/29119336/bariatric-surgery-as-an-efficient-treatment-for-non-alcoholic-fatty-liver-disease-in-a-prospective-study-with-1-year-follow-up-bariscan-study
#8
Felix Nickel, Christian Tapking, Laura Benner, Janina Sollors, Adrian T Billeter, Hannes G Kenngott, Loay Bokhary, Mathias Schmid, Moritz von Frankenberg, Lars Fischer, Sebastian Mueller, Beat P Müller-Stich
BACKGROUND: Bariatric surgery gains attention as a potential treatment for non-alcoholic fatty liver disease (NAFLD). The present study aimed to evaluate improvement of NAFLD after the two most common bariatric procedures with validated non-invasive instruments. MATERIAL AND METHODS: N = 100 patients scheduled for laparoscopic sleeve gastrectomy (LSG) or Roux-en-Y gastric bypass (RYGB) were included. NAFLD was evaluated preoperatively and postoperatively with liver stiffness measurement by transient elastography and laboratory-based fibrosis scores...
November 9, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29117619/development-of-obesity-associated-comorbidities-post-bariatric-surgery-with-a-special-focus-on-diabetes-remission-and-short-term-relapse
#9
Nina Riedel, Anne Lautenbach, Jan Wilhelm Wienecke, Oliver Mann, Jörg Flitsch, Jens Aberle
Purpose The purpose of this study is to study a heterogeneous group of obese patients undergoing Bariatric surgery(BS) and its impact on glycemic control. Secondary endpoints include changes in lipid profile and albuminuria. BS has shown to effectively reduce body-weight. However, the impact on obesity-related comorbidities varies strongly between individuals. Especially postoperative short- and long-term improvement of Diabetes is an active area of investigation. Methods We conducted a retrospective analysis from baseline to 24 months post bariatric surgery in our interdisciplinary obesity outpatient-clinic...
November 8, 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/29116413/cardiovascular-risk-factors-after-single-anastomosis-duodeno-ileal-bypass-with-sleeve-gastrectomy-sadi-s-a-new-effective-therapeutic-approach
#10
REVIEW
Antonio Torres, Miguel A Rubio, Ana M Ramos-Leví, Andrés Sánchez-Pernaute
Obesity and its associated comorbidities entail a significantly increased cardiovascular mortality. Therefore, approaching obesity control must include among its aims the reduction of the associated comorbidities and the higher cardiovascular mortality risk and not only weight loss. Many observational studies indicate that bariatric surgery (BS) is associated with a better long-term survival than standard care. Furthermore, in general, these epidemiological studies included patients who underwent gastric bypass (GB), not biliopancreatic diversion/duodenal switch (BPD/DS), so the potential additional benefit of this latter technique remains unknown...
November 7, 2017: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/29113813/altered-glucose-metabolism-after-bariatric-surgery-what-s-glp-1-got-to-do-with-it
#11
REVIEW
Eric P Smith, Georgina Polanco, Abid Yaqub, Marzieh Salehi
Bariatric surgery is an effective treatment for obesity. The two widely performed weight-loss procedures, Roux-en-Y gastric bypass (GB) and sleeve gastrectomy (SG), alter postprandial glucose pattern and enhance gut hormone secretion immediately after surgery before significant weight loss. This weight-loss independent glycemic effects of GB has been attributed to an accelerated nutrient transit from stomach pouch to the gut and enhanced secretion of insulinotropic gut factors; in particular, glucagon-like peptide-1 (GLP-1)...
November 4, 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29110243/problematic-alcohol-use-and-associated-characteristics-following-bariatric-surgery
#12
Kathryn E Smith, Scott G Engel, Kristine J Steffen, Luis Garcia, Karen Grothe, Afton Koball, James E Mitchell
PURPOSE: Evidence suggests that a significant minority of individuals who undergo Roux-en-Y gastric bypass (RYGB) experience problematic alcohol and substance use following surgery. However, little research has examined characteristics, drinking patterns, and possible risk factors within this population. To provide descriptive information of a sample of adults with self-identified alcohol use problems following bariatric surgery, this study examined (1) alcohol and substance use symptoms using standardized assessments, (2) current and past psychiatric comorbidity, (3) subjective changes in alcohol sensitivity following surgery, and (4) specific patterns of alcohol use prior to and following bariatric surgery...
November 6, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29101558/perioperative-bleeding-and-blood-transfusion-are-major-risk-factors-for-venous-thromboembolism-following-bariatric-surgery
#13
Alexander W Nielsen, Melissa C Helm, Tammy Kindel, Rana Higgins, Kathleen Lak, Zachary M Helmen, Jon C Gould
BACKGROUND: Morbidly obese patients are at increased risk for venous thromboembolism (VTE) after bariatric surgery. Perioperative chemoprophylaxis is used routinely with bariatric surgery to decrease the risk of VTE. When bleeding occurs, routine chemoprophylaxis is often withheld due to concerns about inciting another bleeding event. We sought to evaluate the relationship between perioperative bleeding and postoperative VTE in bariatric surgery. METHODS: The American College of Surgeons-National Surgical Quality Improvement Program (NSQIP) dataset between 2012 and 2014 was queried to identify patients who underwent bariatric surgery...
November 3, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29095195/safety-of-revision-sleeve-gastrectomy-compared-to-roux-y-gastric-bypass-after-failed-gastric-banding-analysis-of-the-mbsaqip
#14
Michał R Janik, Tomasz G Rogula, Rami R Mustafa, Adel Alhaj Saleh, Leena Khaitan
OBJECTIVE: The aim of this study was to assess the safety of revisional surgery to laparoscopic sleeve gastrectomy (LSG) compared to laparoscopic Roux-Y gastric bypass (LRYGB) after failed laparoscopic adjustable gastric banding (LAGB). BACKGROUND: The number of reoperations after failed gastric banding rapidly increased in the United States during the last several years. A common approach is band removal with conversion to another weight loss procedure such as gastric bypass or sleeve gastrectomy in a single procedure...
October 31, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29080645/vitamin-d-metabolism-in-bariatric-surgery
#15
REVIEW
Marlene Chakhtoura, Maya Rahme, Ghada El-Hajj Fuleihan
Hypovitaminosis D is common in obese patients and persists after roux-en-Y gastric bypass and sleeve gastrectomy. Several societies recommend screening for vitamin D deficiency before bariatric surgery, and replacement doses of 3000 IU/d and up to 50,000 IU 1 to 3 times per week, in case of deficiency, with periodic monitoring. These regimens are mostly based on expert opinion. Large trials are needed to assess the vitamin D dose response, by type of bariatric surgery, and evaluate the effect on surrogate markers of skeletal outcomes...
December 2017: Endocrinology and Metabolism Clinics of North America
https://www.readbyqxmd.com/read/29080042/a-retrospective-2-year-follow-up-of-late-complications-treated-surgically-and-endoscopically-after-laparoscopic-roux-en-y-gastric-bypass-lrygb-and-laparoscopic-sleeve-gastrectomy-lsg-for-morbid-obesity
#16
Mervi Javanainen, Anne Penttilä, Harri Mustonen, Anne Juuti, Tom Scheinin, Marja Leivonen
BACKGROUND: The laparoscopic Roux-en-Y gastric bypass (LRYGB) has been the gold standard for bariatric surgery, but recently, the laparoscopic sleeve gastrectomy (LSG) has gained popularity. At present, limited data is available on the long-term complications of these two types of surgery. The aim of this retrospective study was to compare the 2-year data about late (more than 30 days after surgery) complications that were treated surgically or endoscopically after LRYGB and LSG operations in a large hospital area with a single patient database...
October 28, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29079385/the-role-of-routine-abdominal-drainage-after-bariatric-surgery-a-metabolic-and-bariatric-surgery-accreditation-and-quality-improvement-program-study
#17
Aristithes G Doumouras, Azusa Maeda, Timothy D Jackson
BACKGROUND: The efficacy of drains has long been debated in bariatric surgery. Drains may provide some theoretical benefits to early detection of anastomotic leaks and potential nonoperative treatment; however, there has never been data to support the practice. OBJECTIVE: The objective of this study was to evaluate the effect of drain placement after bariatric surgery. SETTING: This retrospective cohort study includes all hospitals in the United States that participated in the 2015 Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program...
August 31, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29079384/effects-of-bariatric-surgery-on-glycemic-and-lipid-metabolism-surgical-complication-and-quality-of-life-in-adolescents-with-obesity-a-systematic-review-and-meta-analysis
#18
Lin Qi, Yan Guo, Chao-Qian Liu, Zhi-Ping Huang, Yuan Sheng, Da-Jin Zou
BACKGROUND: Obesity in adolescents is associated with numerous health risks and co-morbidities, including type 2 diabetes and dyslipidemia. Bariatric surgery on adolescents induces weight loss, but little is known about metabolic effects of these operations. OBJECTIVE: To explore weight loss and metabolic effects of bariatric surgery on young people. SETTING: A systematic review and meta-analysis. University Hospital, China. METHODS: PubMed and EMBASE were searched for relevant studies up to July 2017...
September 19, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29076010/patient-characteristics-procedural-and-safety-outcomes-of-bariatric-surgery-in-england-a-retrospective-cohort-study-2006-2012
#19
Sun Sun, Oleg Borisenko, Tim Spelman, Ahmed R Ahmed
BACKGROUND: The objective of the study is to analyze procedural and safety outcomes associated with bariatric surgery and describe the characteristics of patients undertaking bariatric procedures in England between April 2006 and March 2012. METHODS: This is a retrospective cohort study of all adult patients in England diagnosed with obesity and undergoing bariatric surgery as a primary procedure in NHS-funded sites between April 2006 and March 2012 using data sourced from the Hospital Episode Statistics dataset...
October 26, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29071067/the-birmingham-experience-of-high-pressure-methylene-blue-dye-test-during-primary-and-revisional-bariatric-surgery-a-retrospective-cohort-study
#20
G C Kirby, C A W Macano, S M Nyasavajjala, M Sahloul, R Nijjar, M Daskalakis, M Richardson, R Singhal
INTRODUCTION: Leak following bariatric surgery continues to be associated with morbidity and rarely mortality. With improvement in surgical techniques and stapler design, leak rates have reduced drastically. Intra-operative high pressure Methylene blue leak test (HPMB) is one of the techniques employed to confirm integrity of anastomoses and staple lines. Despite this, evidence for its use remains limited. We evaluated the role of HPMB in detecting and preventing leaks. METHODS: A retrospective cohort of consecutive patients who underwent primary or revisional Laparoscopic Sleeve Gastrectomy (SG) or Laparoscopic Roux-en-Y Gastric bypass (RYGB) under the care of five surgeons in three centres across Birmingham, UK, between 2012 and 2016 were assessed...
November 2017: Annals of Medicine and Surgery
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