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https://www.readbyqxmd.com/read/29036963/-common-questions-about-clinical-management-of-complicated-urinary-tract-infections
#1
Y Ge
No abstract text is available yet for this article.
October 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29036682/perinatal-risk-factors-for-neonatal-early-onset-group-b-streptococcal-sepsis-after-initiation-of-risk-based-maternal-intrapartum-antibiotic-prophylaxis-a-case-control-study
#2
Sridhar Santhanam, Sumita Arun, Grace Rebekah, Nithya J Ponmudi, Jolly Chandran, Ruby Jose, Atanu Kumar Jana
Objectives: To identify the perinatal risk factors for early-onset Group B Streptococcus (EOGBS) sepsis in neonates after inception of a risk-based maternal intrapartum antibiotic prophylaxis strategy in 2004. Design: Case control study. Methods: All newborn with early onset GBS sepsis (born between 2004 and 2013) were deemed to be "cases" and controls were selected in a 1:4 ratio. Results: More than three per vaginal (PV) examinations [odds ratio (OR) 8...
September 23, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29036646/de-novo-deleterious-sequence-variants-that-alter-the-transcriptional-activity-of-the-homeoprotein-pbx1-are-associated-with-intellectual-disability-and-pleiotropic-developmental-defects
#3
Anne Slavotinek, Maurizio Risolino, Marta Losa, Megan T Cho, Kristin G Monaghan, Dina Schneidman-Duhovny, Sarah Parisotto, Johanna C Herkert, Alexander P A Stegmann, Kathryn Miller, Natasha Shur, Jacqueline Chui, Eric Muller, Suzanne DeBrosse, Justin O Szot, Gavin Chapman, Nicholas S Pachter, David S Winlaw, Bryce A Mendelsohn, Joline Dalton, Kyriakie Sarafoglou, Peter I Karachunski, Jane M Lewis, Helio Pedro, Sally L Dunwoodie, Licia Selleri, Joseph Shieh
We present eight patients with de novo, deleterious sequence variants in the PBX1 gene. PBX1 encodes a three amino acid loop extension (TALE) homeodomain transcription factor that forms multimeric complexes with TALE and HOX proteins to regulate target gene transcription during development. As previously reported, Pbx1 homozygous mutant mice (Pbx1-/-) develop malformations and hypoplasia or aplasia of multiple organs, including the craniofacial skeleton, ear, branchial arches, heart, lungs, diaphragm, gut, kidneys, and gonads...
September 22, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/29036204/metabolic-phenotyping-in-the-mouse-model-of-urinary-tract-infection-shows-that-3-hydroxybutyrate-in-plasma-is-associated-with-infection
#4
Pei Han, Yong Huang, Yumin Xie, Wu Yang, Yaoyao Wang, Wenying Xiang, Peter J Hylands, Cristina Legido-Quigley
Urinary tract infection is one of the most common bacterial infections worldwide. Current diagnosis of urinary tract infection chiefly relies on its clinical presentation, urine dipstick tests and urine culture. Small molecules found in bio-fluids related with both infection and recovery would facilitate diagnosis and management of UTI. Mass spectrometry-based fingerprinting of plasma and urine at 3 time points, pre-infection (t = -24h), infection (t = 24h) and post 3-day treatment (t = 112h), were acquired in the following four groups: mice which were healthy, infected but not treated, infected and treated with ciprofloxacin, and infected and treated with Relinqing® granules (n = 6 per group)...
2017: PloS One
https://www.readbyqxmd.com/read/29036000/unilateral-submandibular-gland-atrophy-and-sialolithiasis-diagnosed-on-99mtc-mibi-spect-ct-in-a-patient-with-primary-hyperparathyroidism
#5
Puskar Pattanayak, Prasanna Santhanam, Mehrbod Som Javadi, Lilja B Solnes, Steven P Rowe
A variety of sequelae of elevated calcium levels are encountered in patients with underlying primary hyperparathyroidism, including stone formation such as calculi in the urinary tract and sialoliths in the salivary glands and ducts. We present a case of a 54-year-old woman with fatigue, myalgia, and poor concentration who was found to have hypercalcemia (corrected calcium, 11.2 mg/dL) and elevated parathyroid hormone level (112 pg/mL), laboratory values consistent with primary hyperparathyroidism. She underwent evaluation with a Tc-MIBI parathyroid SPECT scan that included x-ray CT acquisitions for anatomical localization and attenuation correction...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29035286/urocytological-evaluation-of-pemphigus-patients-on-long-term-cyclophosphamide-therapy-a-cross-sectional-study
#6
Sujay Khandpur, Saurabh Singh, Saumyaranjan Mallick, Vinod Kumar Sharma, Venkat Iyer, Amlesh Seth, Mahesh Kumawat
BACKGROUND: Cyclophosphamide therapy is associated with several urological complications including urinary bladder malignancy. Data on urologic complications of chronic cyclophosphamide therapy for dermatologic conditions is not available. OBJECTIVES: To study the urocytological profile of pemphigus patients on long-term cyclophosphamide therapy. MATERIALS AND METHODS: In a cross-sectional study, consecutive patients who had received cyclophosphamide therapy for pemphigus for more than 12 months were included...
November 2017: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/29035239/diagnosis-of-trichomoniasis-in-male-patients-on-performing-nested-polymerase-chain-reaction
#7
T Mutlu Yar, Mehmet Karakuş, Seray Töz, Aysun Bay Karabulut, Yusuf Özbel, Metin Atambay
OBJECTIVE: Trichomoniasis is a parasitic infection that occurs with the settlement of Trichomonas vaginalis in female and male urinary and reproductive tracts. This infection is generally asymptomatic in males, and males are thought to be a carrier for the transmission of infection. In this study, our aim was to detect trichomoniasis using nested polymerase chain reaction among males who were referred to a hospital with suspected urinary tract infection. METHODS: Urine samples were collected from 138 male patients between 18 and 50 years of age who were referred with suspected urinary system infection to the Urology Outpatient Clinic at Malatya University Medical Center Malatya between December 2013 and May 2014...
September 2017: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/29033364/-recurrent-cystisis-no-medicine-preventive-means
#8
J Armelle
OBJECTIVE: To estimate from the literature review, the interest of hygienic and behavioural measures and the use of food supplements (herbal) to prevent female urinary tract infection. METHODS: Pubmed research was focused on the efficiency of prophylactic measures in recurrent cystisis management. RESULTS: Due to many predisposing factors such as anatomical charasteristics, hydration and lifestyle, cystisis is more common in female subjects than in male...
October 12, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/29032850/impact-of-penicillin-allergy-on-time-to-first-dose-of-antimicrobial-therapy-and-clinical-outcomes
#9
Erin L Conway, Ken Lin, John A Sellick, Kari Kurtzhalts, James Carbo, Michael C Ott, Kari A Mergenhagen
PURPOSE: The objective of this study was to evaluate the impact of a listed penicillin allergy on the time to first dose of antibiotic in a Veterans Affairs hospital. Additional clinical outcomes of patients with penicillin allergies were compared with those of patients without a penicillin allergy. METHODS: A retrospective chart review of veterans admitted through the emergency department with a diagnosis of pneumonia, urinary tract infection, bacteremia, and sepsis from January 2006 to December 2015 was conducted...
October 9, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/29032235/variation-in-radiologic-and-urologic-computed-tomography-interpretation-of-urinary-tract-stone-burden-results-from-resku
#10
David T Tzou, Dylan Isaacson, Manint Usawachintachit, Zhen J Wang, Kazumi Taguchi, Nancy K Hills, Ryan S Hsi, Benjamin A Sherer, Shalonda Reliford-Titus, Brian Duty, Jonathan Harper, Mathew Sorensen, Roger L Sur, Marshall L Stoller, Thomas Chi
OBJECTIVE: To compare the measured stone burden recorded between urologists and radiologists, and examine how these differences could potentially impact stone management. As current urologic stone surgery guideline recommendations are based on stone size, accurate stone measurements are crucial to direct appropriate treatment. This study investigated the discrepant interpretation that often exists between urologic surgeons and radiologists' estimation of patient urinary stone burden. MATERIALS AND METHODS: From November 2015 through August 2016, new patients prospectively enrolled into the Registry for Stones of the Kidney and Ureter (ReSKU™) were included if they had computed tomography images available and an accompanying official radiologic report at the time of their urologist provider visit...
October 12, 2017: Urology
https://www.readbyqxmd.com/read/29032116/mechanisms-of-action-for-%C3%AE-1-adrenoceptor-blockers-in-storage-symptoms-with-new-insights-into-the-micturition-reflex
#11
REVIEW
Tsuyoshi Hattori, Kimio Sugaya
Elderly patients suffering from lower urinary tract symptoms with benign prostatic hyperplasia (BPH) are widely prescribed α1-adrenoceptor blockers (α1-blockers) to improve voiding and storage symptoms. The mechanism of action for improvements in voiding symptoms is well understood; tonus of the urethra and prostate are decreased and urinary flow rate is increased by α1-blockers. However, the mechanisms underlying storage symptoms have remained unclear, although detrusor hyperactivity has been identified as a significant factor...
October 11, 2017: Life Sciences
https://www.readbyqxmd.com/read/29031769/intra-trigonal-onabotulinum-toxin-a-improves-bladder-symptoms-and-quality-of-life-in-bladder-pain-syndrome-interstitial-cystitis-patients-a-pilot-single-centre-randomized-double-blind-placebo-controlled-trial
#12
R Pinto, D Costa, A Morgado, P Pereira, A Charrua, J Silva, F Cruz
PURPOSE: To compare efficacy and safety of trigonal injections of onabotulinumtoxinA and saline in Bladder Pain Syndrome/Interstitial Cystitis patients. MATERIALS AND METHODS: This phase II study enrolled women with Bladder Pain Syndrome/Interstitial Cystitis >6months and pain ≥4 in 0-10 visual analogue scale, refractory to common treatment. OnabotulinumtoxinA 100U (n=10) or saline (placebo, n=9), were administered as 10 trigonal injections of 1ml. Primary end-point was change from baseline in pain intensity reported at week 12...
October 12, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29031767/cycling-and-male-sexual-and-urinary-function-results-from-a-large-multinational-cross-sectional-study
#13
Mohannad A Awad, Thomas W Gaither, Gregory P Murphy, Thanabhudee Chumnarnsongkhroh, Ian Metzler, Thomas Sanford, Siobhan Sutcliffe, Michael L Eisenberg, Peter R Carroll, E Charles Osterberg, Benjamin N Breyer
PURPOSE: To explore the relation between cycling and urinary and sexual function in a large, multinational sample of men. MATERIALS AND METHODS: Cyclists were recruited to complete a survey through Facebook advertisements and outreach to sporting clubs. Swimmers and runners were recruited as a comparison group. Cyclists were categorized into low and high intensity cyclists. Participants were queried using validated questionnaires, including the Sexual Health Inventory for Men (SHIM), International Prostate Symptom Score (I-PSS), and National Institute of Health Chronic Prostatitis Symptom Index (NIH-CPSI), in addition to questions about urinary tract infections (UTIs), urethral strictures, genital numbness, and saddle sores...
October 12, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29031682/-rates-of-total-and-free-psa-prescriptions-in-france-2012-2014
#14
Philippe Tuppin, Claire Leboucher, Gabrielle Peyre-Lanquar, Pierre-Jean Lamy, Pierre Gabach, Xavier Rébillard
BACKGROUND: In 2010, the French Haute Autorité de santé (National Health Authority) confirmed the limited value of prostate cancer (PCa) screening by total prostate-specific antigen (PSA) assay. OBJECTIVE: This study was designed to determine the modalities of ordering total PSA or free PSA assays (in the absence of PCa) according to various parameters and the corresponding sums reimbursed. METHODS: Men aged 40 years and older covered by the national health insurance general scheme (73% of the French population) between 2012 and 2014 were selected...
October 11, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/29031498/low-free-triiodothyronine-at-admission-predicts-poststroke-infection
#15
Satoshi Suda, Junya Aoki, Takashi Shimoyama, Kentaro Suzuki, Yuki Sakamoto, Takehiro Katano, Seiji Okubo, Chikako Nito, Yasuhiro Nishiyama, Masahiro Mishina, Kazumi Kimura
BACKGROUND: Poststroke infection (PSI) is common and is usually associated with a severe prognosis. We investigated the association between PSI and thyroid hormones, which are critical to immune regulation, in patients with acute stroke. METHODS: We retrospectively enrolled 520 consecutive patients with acute ischemic stroke (326 men; age, 71.9 ± 13.2 years) admitted to our department between September 2014 and June 2016. The impact of serum thyroid hormone levels measured at admission (thyroid-stimulating hormone [TSH], free triiodothyronine [FT3], and free thyroxine [FT4]) on the PSI was evaluated using multivariate logistic regression analysis...
October 11, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29031453/whole-genome-comparison-of-urinary-pathogenic-escherichia-coli-and-faecal-isolates-of-uti-patients-and-healthy-controls
#16
Karen Leth Nielsen, Marc Stegger, Kristoffer Kiil, Paul A Godfrey, Michael Feldgarden, Berit Lilje, Paal S Andersen, Niels Frimodt-Møller
The faecal flora is a common reservoir for urinary tract infection (UTI), and Escherichia coli (E. coli) is frequently found in this reservoir without causing extraintestinal infection. We investigated these E. coli reservoirs by whole-genome sequencing a large collection of E. coli from healthy controls (faecal), who had never previously had UTI, and from UTI patients (faecal and urinary) sampled from the same geographical area. We compared MLST types, phylogenetic relationship, accessory genome content and FimH type between patient and control faecal isolates as well as between UTI and faecal-only isolates, respectively...
September 14, 2017: International Journal of Medical Microbiology: IJMM
https://www.readbyqxmd.com/read/29031295/competitive-amperometric-immunosensor-for-determination-of-p53-protein-in-urine-with-carbon-nanotubes-gold-nanoparticles-screen-printed-electrodes-a-potential-rapid-and-noninvasive-screening-tool-for-early-diagnosis-of-urinary-tract-carcinoma
#17
Marco Giannetto, Maria Vittoria Bianchi, Monica Mattarozzi, Maria Careri
Since p53 protein has become recognized biomarker for both diagnostic and therapeutic purposes in oncological diseases with particular relevance for bladder cancer, it is highly desirable to search for a novel sensing tool for detecting the patient's p53 level at the early stage. Here we report the first study on the development and validation of a novel disposable competitive amperometric immunosensor for determination of p53 protein at subnanomolar levels, based on p53 immobilization on gold nanoparticles/carbon nanotubes modified screen-printed carbon electrodes...
October 23, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29031032/the-frequency-and-clinical-implications-of-bacteriuria-in-chronically-paralyzed-dogs
#18
S R Baigi, S Vaden, N J Olby
BACKGROUND: Paralysis is a known risk factor for urinary tract infections (UTI), sepsis, and death in paralyzed people, but there are no data available on diagnostic criteria for UTI versus bacteriuria, their frequency, or clinical implications in chronically paralyzed dogs. HYPOTHESIS/OBJECTIVES: That chronically paralyzed dogs suffer frequent bacteriuria causing reduced duration of survival. We documented the frequency of bacteriuria, associated clinical signs, and survival rate in chronically paralyzed dogs...
October 14, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29030135/staphylococcus-saprophyticus-which-%C3%AE-lactam
#19
Hélène Pailhoriès, Viviane Cassisa, Rachel Chenouard, Marie Kempf, Matthieu Eveillard, Carole Lemarié
OBJECTIVES: Staphylococcus saprophyticus (SS) is resistant to molecules often used in empiric treatment of urinary-tract infections (UTI). The adequacy of antimicrobial treatments prescribed for UTI due to SS is not usually questioned. We described the epidemiology of those infections and assessed the susceptibility of SS to ceftriaxone and amoxicillin-clavulanic acid. METHODS: From November 2014 to July 2016, the methicillin susceptible SS (MSSS) isolated from clinical samples were included...
October 10, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29029581/prevalence-of-urinary-tract-infections-mimicking-respiratory-infections-and-risk-factors-associated
#20
Kalid Bouaghroum, Pierre-Luc Genillier, Dominique Neri, Djamel Lameche, Matteo Vassallo
No abstract text is available yet for this article.
October 13, 2017: Infectious Diseases
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