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https://www.readbyqxmd.com/read/28743074/coronary-perfusion-pressure-and-compression-quality-in-maternal-cardiopulmonary-resuscitation-in-supine-and-left-lateral-tilt-positions-a-prospective-crossover-study-using-mannequins-and-swine-models
#1
Satoshi Dohi, Kiyotake Ichizuka, Ryu Matsuoka, Kohei Seo, Masaaki Nagatsuka, Akihiko Sekizawa
OBJECTIVE: The risk of maternal and fetal mortality is high if cardiopulmonary arrest occurs during pregnancy. To assess the best position for maternal cardiopulmonary resuscitation (CPR), a prospective randomized crossover study was undertaken, involving basic life support mannequin-based simulation (BLS-MS) and a swine model of pulseless electrical activity (an unstable cardiac state) incorporating a fetal mannequin (PEA-FM). STUDY DESIGN: The BLS-MS (performed by certified rescuers) served to evaluate the quality of chest compressions in 30° left lateral tilt (LLT) and supine positions...
July 16, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28742115/mind-wandering-during-attention-performance-effects-of-adhd-inattention-symptomatology-negative-mood-ruminative-response-style-and-working-memory-capacity
#2
Lisa M Jonkman, C Rob Markus, Michael S Franklin, Jens H van Dalfsen
OBJECTIVE: In adulthood, depressive mood is often comorbid with ADHD, but its role in ADHD-inattentiveness and especially relations with mind wandering remains to be elucidated. This study investigated the effects of laboratory-induced dysphoric mood on task-unrelated mind wandering and its consequences on cognitive task performance in college students with high (n = 46) or low (n = 44) ADHD-Inattention symptomatology and Hyperactivity/Impulsivity symptoms in the normal range. METHODS: These non-clinical high/low ADHD-Inattention symptom groups underwent negative or positive mood induction after which mind wandering frequency was measured in a sustained attention (SART), and a reading task...
2017: PloS One
https://www.readbyqxmd.com/read/28742079/the-dcdc2-deletion-is-not-a-risk-factor-for-dyslexia
#3
T S Scerri, E Macpherson, A Martinelli, W C Wa, A P Monaco, J Stein, M Zheng, C Suk-Han Ho, C McBride, M Snowling, C Hulme, M E Hayiou-Thomas, M M Y Waye, J B Talcott, S Paracchini
Dyslexia is a specific impairment in learning to read and has strong heritability. An intronic deletion within the DCDC2 gene, with ~8% frequency in European populations, is increasingly used as a marker for dyslexia in neuroimaging and behavioral studies. At a mechanistic level, this deletion has been proposed to influence sensory processing capacity, and in particular sensitivity to visual coherent motion. Our re-assessment of the literature, however, did not reveal strong support for a role of this specific deletion in dyslexia...
July 25, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28741081/capuchin-monkeys-use-of-human-and-conspecific-cues-to-solve-a-hidden-object-choice-task
#4
Jennifer L Essler, Lindsay P Schwartz, Mattea S Rossettie, Peter G Judge
Learning by watching others can provide valuable information with adaptive consequences, such as identifying the presence of a predator or locating a food source. The extent to which nonhuman animals can gain information by reading the cues of others is often tested by evaluating responses to human gestures, such as a point, and less often evaluated by examining responses to conspecific cues. We tested whether ten brown capuchin monkeys (Cebus [Sapajus] apella) were able to use cues from monkeys and a pointing cue from a human to obtain hidden rewards...
July 24, 2017: Animal Cognition
https://www.readbyqxmd.com/read/28740351/partners-of-patients-with-ulcerative-colitis-exhibit-a-biologically-relevant-dysbiosis-in-fecal-microbial-metacommunities
#5
Guang-Lan Chen, Ye Zhang, Wang-Yue Wang, Xue-Liang Ji, Fei Meng, Pei-Song Xu, Ning-Min Yang, Fu-Qiang Ye, Xiao-Chen Bo
AIM: To investigate alterations in the fecal microbiome using 16S rRNA amplicon sequencing in couples in the same cohabitation environment. METHODS: Fecal samples were collected from eight ulcerative colitis (UC) patients and their healthy partners at Lishui People's Hospital, Zhejiang Province, China. DNA was extracted and the variable regions V3 and V4 of the 16S rRNA genes were PCR amplified using a two-step protocol. Clear reads were clustered into operational taxonomic units (OTUs) at the 97% sequence similarity level using UCLUST v1...
July 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28739142/radiation-therapy-for-oligorecurrence-in-prostate-cancer-preliminary-results-of-our-centre
#6
C González Ruiz de León, M Ramírez Backhaus, M Sobrón Bustamante, J Casaña, L Arribas, J Rubio-Briones
INTRODUCTION AND OBJECTIVE: There is growing interest in the use of more aggressive therapeutic modalities for treating metastatic prostate cancer. In this study, we examine the use of stereotactic body radiation therapy (SBRT) for patients with oligorecurrent prostate cancer. We analysed the biochemical response and toxicity of patients who underwent this therapy at our centre. MATERIAL AND METHOD: We selected patients who experienced oligorecurrence between January 2015 to December 2016 and were administered SBRT...
July 21, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/28738868/comparative-evaluation-of-fluorescent-in-situ-hybridization-and-giemsa-microscopy-with-quantitative-real-time-pcr-technique-in-detecting-malaria-parasites-in-a-holoendemic-region-of-kenya
#7
Joseph Osoga, John Waitumbi, Bernard Guyah, James Sande, Cornel Arima, Michael Ayaya, Caroline Moseti, Collins Morang'a, Martin Wahome, Rachel Achilla, George Awinda, Nancy Nyakoe, Elizabeth Wanja
BACKGROUND: Early and accurate diagnosis of malaria is important in treatment as well as in the clinical evaluation of drugs and vaccines. Evaluation of Giemsa-stained smears remains the gold standard for malaria diagnosis, although diagnostic errors and potential bias estimates of protective efficacy have been reported in practice. Plasmodium genus fluorescent in situ hybridization (P-Genus FISH) is a microscopy-based method that uses fluorescent labelled oligonucleotide probes targeted to pathogen specific ribosomal RNA fragments to detect malaria parasites in whole blood...
July 24, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28738163/a-local-duplication-of-the-i-melanocortin-receptor-1-i-locus-in-i-astyanax-i
#8
Joshua B Gross, James Weagley, Bethany A Stahl, Li Ma, Luis Espinasa, Suzanne E McGaugh
In this study, we report evidence of a novel duplication of <i>Melanocortin receptor 1 (Mc1r)</i> in the cavefish genome. This locus was discovered following the observation of excessive allelic diversity in a ~820 bp fragment of <i>Mc1r</i> amplified via degenerate PCR from a natural population of <i>Astyanax aeneus</i> fish from Guerrero, Mexico. The cavefish genome reveals the presence of two closely related <i>Mc1r</i> open reading frames separated by a 1...
July 24, 2017: Genome Génome / Conseil National de Recherches Canada
https://www.readbyqxmd.com/read/28736318/psma-targeted-18-f-dcfpyl-pet-ct-in-the-preoperative-staging-of-men-with-high-risk-prostate-cancer-results-of-a-prospective-phase-ii-single-center-study
#9
Michael A Gorin, Steven P Rowe, Hiten D Patel, Igor Vidal, Margarita Mana-Ay, Mehrbod S Javadi, Lilja B Solnes, Ashley E Ross, Edward M Schaeffer, Trinity J Bivalacqua, Alan W Partin, Kenneth J Pienta, Zsolt Szabo, Angelo M De Marzo, Martin G Pomper, Mohamad E Allaf
PURPOSE: To prospectively evaluate the diagnostic performance of PSMA-targeted (18)F-DCFPyL PET/CT in the preoperative staging of men at high risk of harboring metastatic prostate cancer despite a negative conventional staging evaluation. MATERIALS AND METHODS: Men with clinically localized high or very-high risk prostate cancer were imaged with (18)F-DCFPyL PET/CT prior to undergoing radical prostatectomy with a standardized pelvic lymph node dissection. PET/CT scans were interpreted by two blinded nuclear medicine readers and were assessed for inter-reader variability as well as diagnostic accuracy for pelvic lymph node staging...
July 20, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28736204/neural-stability-a-reflection-of-automaticity-in-reading
#10
Silvia Siu-Yin Lam, Travis White-Schwoch, Steven G Zecker, Jane Hornickel, Nina Kraus
Automaticity, the ability to perform a task rapidly with minimal effort, plays a key role in reading fluency and is indexed by rapid automatized naming (RAN) and processing speed. Yet little is known about automaticity's neurophysiologic underpinnings. The more efficiently sound is encoded, the more automatic sound processing can be. In turn, this automaticity could free up cognitive resources such as attention and working memory to help build an integrative reading network. Therefore, we hypothesized that automaticity and reading fluency correlate with stable neural representation of sounds, given a larger body of literature suggesting the close relationship between neural stability and the integrative function in the central auditory system...
July 20, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28736039/cloning-identification-and-characterization-of-a-novel-%C3%AE%C2%BA-carrageenase-from-marine-bacterium-cellulophaga-lytica-strain-n5-2
#11
Hongli Cui, Yuxin Peng, Bowen Zhao, Yuqing Liu, Fengjia Chen, Haige Wu, Ziang Yao
A novel κ-carrageenase gene (Cly-κ-car) was cloned and heterologously expressed from marine bacterium Cellulophaga lytica strain N5-2. The gene comprised an open reading frame of 1,488bp encoding 495 amino acid residues. The deduced protein had a calculated molecular weight of 55.24kDa with an estimated isoelectric point of 9.90. Multiple alignment analysis revealed that Cly-κ-CAR shared identity with κ-carrageenases from Zobellia sp. M-2 (46%), Zobellia galactanivorans (42%) and Rhodopirellula islandica (38%)...
July 20, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28735830/-i-just-googled-and-read-everything-exploring-breast-cancer-survivors-use-of-the-internet-to-find-information-on-complementary-medicine
#12
Michelle M Holmes, Felicity L Bishop, Lynn Calman
OBJECTIVE: Breast cancer survivors often turn to the internet as an information resource when deciding whether to use complementary and alternative medicine (CAM) but their use of online CAM-related resources is poorly understood. The objective was to explore breast cancer survivors' use of the internet when making decisions about CAM use. DESIGN: A purposive sample of 11 breast cancer survivors (mean age=56) completed a quantitative questionnaire and a qualitative telephone interview...
August 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28735795/accuracy-of-2-endodontic-rotary-motors-with-integrated-apex-locator
#13
Alessandra Timponi Goes Cruz, Caroline Wichnieski, Everdan Carneiro, Ulisses Xavier da Silva Neto, Gianluca Gambarini, Lucila Piasecki
INTRODUCTION: The purpose of this study was to evaluate in vitro the efficacy of both the electronic apex locator (EAL) and auto apical reverse (AAR) functions of the endodontic motor MM Control (Micro-Mega, Besançon Cedex, France) compared with Root ZX II (J Morita, Tokyo, Japan). METHODS: After cervical preflaring, the actual lengths (ALs) of 36 single-rooted teeth were obtained up to the apical foramen. The EAL measurements at the marks "APEX" and "0.5" of both devices were obtained using an alginate model...
July 20, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28734736/analysis-of-medication-adherence-related-notes-from-a-service-oriented-community-pharmacy
#14
Matthew Witry, Rachel Parry, Randal McDonough, Michael Deninger
BACKGROUND: Medication nonadherence is a significant public health problem. Community pharmacists are positioned to intervene, however, the process is not well understood. OBJECTIVE: To classify and quantify the reasons for nonadherence documented by community pharmacists. METHODS: A retrospective content analysis of pharmacist notes related to nonadherence at a service oriented community pharmacy in the Midwest United States. Notes from the site's dispensing custom documentation software were obtained from September 1, 2014 through February 28, 2015 that were labeled "compliance", either prompted by proportion of days covered calculations or entered as a drug therapy problem...
July 15, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28734637/-asthma-and-heroin-use
#15
Michel Underner, Jean Perriot, Gérard Peiffer, Nematollah Jaafari
INTRODUCTION: Heroin use can be responsible for many respiratory complications including asthma. OBJECTIVES: Systematic literature review of data on asthma in heroin users. DOCUMENTARY SOURCES: Medline(®), on the period 1980-2017 with the following keywords: keywords: "asthma" or "bronchospasm" and "heroin" or "opiate" or "opiates", limits "title/abstract"; the selected languages were English or French. Among 97 articles, 67 abstracts have given use to a dual reading to select 23 studies...
July 19, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/28734592/publishing-with-objective-charisma-breaking-science-s-paradox
#16
Zoë A Doubleday, Sean D Connell
Good writing takes time, but in a research environment where speed is master, is it a superfluous pursuit? Scientists spend most of their working life writing, yet our writing style obstructs its key purpose: communication. We advocate more accessible prose that boosts the influence of our publications. For those who change, the proof of their success will be science that is read, understood, and remembered.
July 19, 2017: Trends in Ecology & Evolution
https://www.readbyqxmd.com/read/28733102/transcriptome-landscape-of-human-primary-monocytes-at-different-sequencing-depth
#17
Hoda Mirsafian, Adiratna Mat Ripen, Wai-Mun Leong, Thamilvaani Manaharan, Saharuddin Bin Mohamad, Amir Feisal Merican
Differential gene and transcript expression pattern of human primary monocytes from healthy young subjects were profiled under different sequencing depths (50M, 100M, and 200M reads). The raw data consisted of 1.3 billion reads generated from RNA sequencing (RNA-Seq) experiments. A total of 17,657 genes and 75,392 transcripts were obtained at sequencing depth of 200M. Total splice junction reads showed an even more significant increase. Comparative analysis of the expression patterns of immune-related genes revealed a total of 217 differentially expressed (DE) protein-coding genes and 50 DE novel transcripts, in which 40 DE protein-coding genes were related to the immune system...
July 18, 2017: Genomics
https://www.readbyqxmd.com/read/28732589/accuracy-of-diagnostic-imaging-modalities-for-classifying-pediatric-eyes-as-papilledema-versus-pseudopapilledema
#18
Melinda Y Chang, Federico G Velez, Joseph L Demer, Laura Bonelli, Peter A Quiros, Anthony C Arnold, Alfredo A Sadun, Stacy L Pineles
PURPOSE: To identify the most accurate diagnostic imaging modality for classifying pediatric eyes as papilledema (PE) or pseudopapilledema (PPE). DESIGN: Prospective observational study. SUBJECTS: Nineteen children between the ages of 5 and 18 years were recruited. Five children (10 eyes) with PE, 11 children (19 eyes) with PPE owing to suspected buried optic disc drusen (ODD), and 3 children (6 eyes) with PPE owing to superficial ODD were included...
July 18, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28731476/exact-sequence-variants-should-replace-operational-taxonomic-units-in-marker-gene-data-analysis
#19
Benjamin J Callahan, Paul J McMurdie, Susan P Holmes
Recent advances have made it possible to analyze high-throughput marker-gene sequencing data without resorting to the customary construction of molecular operational taxonomic units (OTUs): clusters of sequencing reads that differ by less than a fixed dissimilarity threshold. New methods control errors sufficiently such that amplicon sequence variants (ASVs) can be resolved exactly, down to the level of single-nucleotide differences over the sequenced gene region. The benefits of finer resolution are immediately apparent, and arguments for ASV methods have focused on their improved resolution...
July 21, 2017: ISME Journal
https://www.readbyqxmd.com/read/28730173/surface-coil-intensity-correction-in-magnetic-resonance-imaging-in-spinal-metastases
#20
Hong Ren, Wei Lin, Xianjun Ding
OBJECTIVE: To evaluate the clinical application of phased-array surface coil intensity correction in magnetic resonance imaging (MRI) in spinal metastases. METHODS: 3 phantoms and 50 patients with a corresponding total number of 80 spinal metastases were included in this study. Fast spin echo T1- and T2- weighted MRI with and without surface coil intensity correction was routinely performed for all phantoms and patients. Phantoms were evaluated by means of variance to mean ratio of signal intensity on both T1- and T2- weighted MRI obtained with and without surface coil intensity correction...
2017: Open Medicine (Warsaw, Poland)
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