keyword
MENU ▼
Read by QxMD icon Read
search

Difficult

keyword
https://www.readbyqxmd.com/read/27915422/state-of-the-art-review-of-the-right-ventricle-in-copd-patients-it-is-time-to-look-closer
#1
REVIEW
Daniela Graner Schuwartz Tannus-Silva, Marcelo Fouad Rabahi
Since the first description of pulmonary circulation in the 16th century, the knowledge of the complex interaction between the heart and lungs has greatly improved. Hypoxemia plays a classical role in the development of complications such as pulmonary hypertension and right ventricle (RV) dysfunction in patients presenting with chronic obstructive pulmonary disease (COPD). However, more recent results have revealed the presence of RV vascular structural and functional changes even in patients with mild COPD, without hypoxemia or pulmonary hypertension at rest...
December 3, 2016: Lung
https://www.readbyqxmd.com/read/27915372/surgical-treatment-of-neuroendocrine-tumors-in-the-second-portion-of-the-duodenum-a-single-center-experience-and-systematic-review-of-the-literature
#2
Toshimitsu Iwasaki, Satoshi Nara, Yoji Kishi, Minoru Esaki, Kazuaki Shimada, Nobuyoshi Hiraoka
PURPOSE: The treatment of choice for duodenal neuroendocrine tumors (NETs) ranges from endoscopic resection and local excision to pancreaticoduodenectomy. The aim of this study was to investigate the optimal treatment for this tumor. METHODS: We retrospectively analyzed the clinicopathological data of 14 patients with NETs in the second portion of the duodenum who underwent surgery in our hospital from 2000 to 2015. The duodenal NETs were classified as either ampullary or non-ampullary...
December 3, 2016: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/27915241/xanthogranulomatous-pyelonephritis-presenting-as-proteus-preperitoneal-abscess
#3
Yuyi Yeow, Yew-Lam Chong
Xanthogranulomatous pyelonephritis (XGPN) is a rare form of chronic pyelonephritis with progressive loss of renal function. Commonly, obstructing urinary calculi are seen. It is difficult to differentiate between XGPN and malignancy in many cases, and the diagnosis is usually only confirmed post-operatively upon histopathological examination of the specimen. Surgical treatment is often the main treatment modality due to suspicion for malignancy. Here, we present a case of XGPN that presented with abdominal distension, which was eventually discovered to be due to a preperitoneal abscess...
December 2, 2016: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/27915114/measurement-and-evaluation-practices-of-factors-that-contribute-to-effective-health-promotion-collaboration-functioning-a-scoping-review
#4
Sean Stolp, Joan L Bottorff, Cherisse L Seaton, Margaret Jones-Bricker, John L Oliffe, Steven T Johnson, Sally Errey, Kerensa Medhurst, Sonia Lamont
The purpose of this scoping review was to identify promising factors that underpin effective health promotion collaborations, measurement approaches, and evaluation practices. Measurement approaches and evaluation practices employed in 14 English-language articles published between January 2001 and October 2015 were considered. Data extraction included research design, health focus of the collaboration, factors being evaluated, how factors were conceptualized and measured, and outcome measures. Studies were methodologically diverse employing either quantitative methods (n=9), mixed methods (n=4), or qualitative methods (n=1)...
November 22, 2016: Evaluation and Program Planning
https://www.readbyqxmd.com/read/27915084/predicting-hospitalization-and-mortality-in-patients-with-heart-failure-the-bardiche-index
#5
Nicole H M K Uszko-Lencer, Lutz Frankenstein, Martijn A Spruit, Micha T Maeder, Marc Gutmann, Stefano Muzzarelli, Stefan Osswald, Matthias E Pfisterer, Christian Zugck, Hans-Peter Brunner-La Rocca
BACKGROUND: Prediction of events in chronic heart failure (CHF) patients is still difficult and available scores are often complex to calculate. Therefore, we developed and validated a simple-to-use, multidimensional prognostic index for such patients. METHODS: A theoretical model was developed based on known prognostic factors of CHF that are easily obtainable: Body mass index (B), Age (A), Resting systolic blood pressure (R), Dyspnea (D), N-termInal pro brain natriuretic peptide (NT-proBNP) (I), Cockroft-Gault equation to estimate glomerular filtration rate (C), resting Heart rate (H), and Exercise performance using the 6-min walk test (E) (the BARDICHE-index)...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27915077/how-do-government-regulations-influence-the-ability-to-practice-chinese-herbal-medicine-in-western-countries
#6
Tom Fleischer, Yi-Chang Su, Sunny Jui-Shan Lin
ETHNOPHARMACOLOGICAL RELEVANCE: The regulation policies of substances used in Chinese Herbal Medicine (CHM), have a direct influence on the ability of health providers to practice in the clinic. AIM OF THE STUDY: We set out to assess the truth behind the assumption that practice of CHM in the west is constrained by the regulations imposed by authorities in western countries. MATERIALS AND METHODS: For the first part of our study we surveyed and compiled lists of banned and restricted Chinese Materia Medica (CMM) from six countries: USA, UK, Germany, Israel, Canada and Australia...
November 30, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27915018/design-and-surface-immobilization-of-short-anti-biofilm-peptides
#7
Biswajit Mishra, Tamara Lushnikova, Radha M Golla, Xiuqing Wang, Guangshun Wang
: Short antimicrobial peptides are essential to keep us healthy and their lasting potency can inspire the design of new types of antibiotics. This study reports the design of a family of eight-residue tryptophan-rich peptides (TetraF2W) obtained by converting the four phenylalanines in temporin-SHf to tryptophans. The temporin-SHf template was identified from the antimicrobial peptide database (http://aps.unmc.edu/AP). Remarkably, the double arginine variant (TetraF2W-RR) was more effective in killing methicillin-resistant Staphylococcus aureus (MRSA) USA300, but less cytotoxic to human skin HaCat and kidney HEK293 cells, than the lysine-containing dibasic combinations (KR, RK and KK)...
November 30, 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/27914889/ventricular-tachycardia-and-prolonged-qt-interval-presenting-as-seizure-like-activity-a-case-report
#8
Max Wentlandt, Stephen C Morris, Steven H Mitchell
Seizures can be difficult to distinguish from other causes of transient cerebral hypoxia in the emergency room. We present a case of seizure activity in a woman in whom EKG led to a diagnosis of intermittent monomorphic and polymorphic ventricular tachycardia (torsades de pointes), highlighting the need for careful consideration of alternative causes of seizures, even in patients with known epilepsy.
November 22, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27914884/clinical-presentation-diagnosis-and-survival-in-cholangiocarcinoma-a-prospective-study
#9
Larisa Vasilieva, Stefanos I Papadhimitriou, Alexandra Alexopoulou, Ioannis Kostopoulos, Konstantinos Papiris, Dimitrios Pavlidis, Dimitrios Xinopoulos, Andreas Romanos, Spyridon P Dourakis
BACKGROUND AND STUDY AIMS: The diagnosis of cholangiocarcinoma (CCA) is difficult. The present study aimed to assess the clinical features, diagnosis, and survival in CCA. PATIENTS AND METHODS: This is a prospective study on 46 patients with CCA who underwent endoscopic retrograde cholangiopancreatography (ERCP) or surgical resection and 20 controls with a clinical and ERCP suspicion for CCA in whom surgical biopsy and/or 4-year follow-up showed a benign biliary stricture...
November 30, 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27914779/what-do-radiation-oncologists-require-for-future-advancements-in-lung-sbrt
#10
REVIEW
Umberto Ricardi, Serena Badellino, Andrea Riccardo Filippi
Stereotactic Body Radiotherapy (SBRT) is a well established therapeutic option for patients affected with peripheral early stage non-small cell lung cancer (NSCLC), given the positive clinical evidence accumulated so far on its efficacy and safety. SBRT is regarded as the best choice for inoperable patients, and could also be offered as an alternative to surgery to selected operable patients. More recently, its use for lung metastases progressively increased, and SBRT is now regarded as a low toxic and highly effective local therapy for lung oligometastases from different primary tumors, especially colorectal cancer...
November 30, 2016: Physica Medica: PM
https://www.readbyqxmd.com/read/27914683/paediatric-cutaneous-adnexal-tumours-a-study-of-559-cases
#11
Amanda M Ireland, Nathan T Harvey, Bligh D Berry, Benjamin A Wood
Cutaneous adnexal tumours encompass a wide group of lesions with apocrine, eccrine, follicular, sebaceous and mixed differentiation. The large majority are benign and represent sporadic lesions, though malignant forms are occasionally encountered and some cases develop in the setting of inherited tumour syndromes. Accurate histological classification can be difficult as there are numerous histological appearances, many of which are individually uncommon, and complex, overlapping and historically variable nomenclature is typical...
November 30, 2016: Pathology
https://www.readbyqxmd.com/read/27914674/heart-failure-induced-by-itraconazole
#12
Ana Rodrigo-Troyano, Marta M Mediavilla, Noé Garin, Rosa Güell
INTRODUCTION AND OBJECTIVE: Itraconazole is an antifungal imidazole used for the treatment of aspergillosis. Evidence supporting the association between itraconazole and the onset of congestive heart failure (CHF) is limited and is based on cases reported after drug market release. CASE REPORT: We report the case of a 76-year-old man with hypertension and COPD GOLD D who experienced heart failure after receiving a new line of treatment with itraconazole. The patient's symptoms resolved completely after the drug's withdrawal and initiation of treatment with diuretic therapy...
November 30, 2016: Medicina Clínica
https://www.readbyqxmd.com/read/27914635/noninvasive-screening-for-pulmonary-hypertension-by-exercise-testing-in-congenital-heart-disease
#13
Jan Müller, Pinar Bambul Heck, Peter Ewert, Alfred Hager
BACKGROUND: Patients with congenital heart disease and native or palliated conditions are at risk to develop pulmonary hypertension (PH) in later life. Screening for PH is currently performed by regular echocardiographic follow-up, which appears to be difficult in several congenital conditions. This study evaluated the screening for PH in congenital heart disease by cardiopulmonary exercise testing (CPET). METHODS: We analyzed our database including all patients with congenital heart disease referred for CPET in our institution from June 2001 to September 2013 and identified 683 patients who had an accompanied heart catheterization less than 6 month after CPET...
November 30, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27914601/effects-of-aquatic-exercise-on-muscle-strength-and-functional-performance-of-individuals-with-osteoarthritis-a-systematic-review
#14
Fernanda de Mattos, Neiva Leite, Arthur Pitta, Paulo Cesar Barauce Bento
Water-based exercises are recommended for people with osteoarthritis (OA), due to the beneficial effects on physical function, quality of life and symptom reduction. However, the effects on muscle strength are still controversial. The aim of this review was to assess and compare the effects of aquatic exercise programs on muscle strength and physical function in people with OA. A systematic search was performed at Pubmed, Scopus and Web of Science databases. Clinical trials with interventions involving aquatic exercises for individuals with OA were included...
November 2016: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/27914585/bladder-augmentation-in-anuric-defunctioned-microbladders-and-a-novel-antireflux-mechanism-for-mitrofanoff-anastomosis-to-the-ileal-patch
#15
Joana Lopes, Andy Robb, Liam McCarthy
BACKGROUND/PURPOSE: Reconstruction of microbladders is a difficult surgical challenge: How can a neobladder be recreated when >90% of the new bladder is augmented patch, and how can a Mitrofanoff conduit be anastomosed when the native bladder is so tiny? This series describes microbladders secondary to anuria and/or diversion that required augmentation. This was done using a de-tubularized ileal segment, and because of the small size of the native bladder, Mitrofanoff anastomosis was performed to the bowel patch (using a novel "Keel Procedure")...
November 13, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27914550/evaluation-of-macroscopic-changes-and-the-efficiency-of-dna-profiling-from-burnt-teeth
#16
Joe Adserias Garriga, Douglas H Ubelaker, Sara C Zapico
Identification of human remains subjected to incineration is extremely challenging. Our study evaluates the macroscopic changes and efficiency of DNA profiling in burnt teeth under controlled temperature and time conditions. 28 teeth were exposed to temperatures between 100 and 700°C for a duration of 1-15min. Two non-burnt teeth were used as control. Macroscopic changes were evaluated and recorded. DNA was extracted using a silica-based methodology. Efficiency of DNA profiling was assessed through Quantitative PCR for STRs...
December 2016: Science & Justice: Journal of the Forensic Science Society
https://www.readbyqxmd.com/read/27914534/novel-revelation-of-warfarin-resistant-mechanism-in-roof-rats-rattus-rattus-using-pharmacokinetic-pharmacodynamic-analysis
#17
Kazuki Takeda, Yoshinori Ikenaka, Tsutomu Tanikawa, Kazuyuki D Tanaka, Shouta M M Nakayama, Hazuki Mizukawa, Mayumi Ishizuka
Roof rats (Rattus rattus) live mainly in human habitats. Heavy use of rodenticides, such as warfarin, has led to the development of drug resistance, making pest control difficult. There have been many reports regarding mutations of vitamin K epoxide reductase (VKOR), the target enzyme of warfarin, in resistant rats. However, it has been suggested there are other mechanisms of warfarin resistance. To confirm these possibilities, closed colonies of warfarin-susceptible roof rats (S) and resistant rats from Tokyo (R) were established, and the pharmacokinetics/pharmacodynamics of warfarin in rats from both colonies was investigated...
November 2016: Pesticide Biochemistry and Physiology
https://www.readbyqxmd.com/read/27914396/laryngeal-muscular-control-of-vocal-fold-posturing-numerical-modeling-and-experimental-validation
#18
Jun Yin, Zhaoyan Zhang
A three-dimensional continuum model of vocal fold posturing was developed to investigate laryngeal muscular control of vocal fold geometry, stiffness, and tension, which are difficult to measure in live humans or in vivo models. This model was able to qualitatively reproduce in vivo experimental observations of laryngeal control of vocal fold posturing, despite the many simplifications which are necessary due to the lack of accurate data of laryngeal geometry and material properties. The results present a first comprehensive study of the co-variations between glottal width, vocal fold length, stiffness, tension at different conditions of individual, and combined laryngeal muscle activation...
September 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27914350/phosphorus-flows-in-a-peri-urban-region-with-intensive-food-production-a-case-study
#19
S Bittman, S C Sheppard, D Poon, D E Hunt
Excess phosphorus (P) in peri-urban regions is an emerging issue, whereas there is global depletion of quality mined supplies of P. The flow of P across the landscape leading to regional surpluses and deficits is not well understood. We computed a regional P budget with internal P flows in a fairly discreet peri-urban region (Lower Fraser Valley, BC) with closely juxtaposed agricultural and non-agricultural urban ecosystems, in order to clarify the relationship between food production, food consumption and other activities involving use of P (e...
November 30, 2016: Journal of Environmental Management
https://www.readbyqxmd.com/read/27914324/development-and-validation-of-species-specific-molecular-diagnostic-tool-for-opisthorchis-felineus-digenea-opisthorchiidae-metacercariae
#20
Monica Caffara, Laura Serracca, Andrea Gustinelli, Walter Vencia, Irene Rossini, Marino Prearo, Maria L Fioravanti
Opisthorchis felineus (family Opisthorchiidae) is a parasitic flatworm representing a serious threat to humans in some countries. Opisthorchiasis occurs after consumption of raw or undercooked cyprinid fish infected by the metacercarial stage of the parasite. Due to its small size, detection of the parasite in fish fillet is time-consuming and difficult. Furthermore, isolated metacercariae can be identified to genus but not to species level using morphological features and molecular techniques are necessary...
November 28, 2016: International Journal of Food Microbiology
keyword
keyword
103358
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"