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https://www.readbyqxmd.com/read/28918494/betaine-in-the-brain-characterization-of-betaine-uptake-its-influence-on-other-osmolytes-and-its-potential-role-in-neuroprotection-from-osmotic-stress
#1
Leena S Knight, Quinn Piibe, Ian Lambie, Christopher Perkins, Paul H Yancey
Betaine (N-trimethylglycine), a common osmolyte, has received attention because of the number of clinical reports associating betaine supplementation with improved cognition, neuroprotection and exercise physiology. However, tissue analyses report little accumulation of betaine in brain tissue despite the presence of betaine/GABA transporters (BGT1) at the blood brain barrier and in nervous tissue, calling into question whether betaine influences neuronal function directly or indirectly. Therefore, the focus of this study was to determine what capacity nervous tissue has to accumulate betaine, specifically in the hippocampus, a region of the brain associated with learning and memory and one that is particularly susceptible to damage (e...
September 16, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28917144/silicon-improves-seed-germination-and-alleviates-drought-stress-in-lentil-crops-by-regulating-osmolytes-hydrolytic-enzymes-and-antioxidant-defense-system
#2
Sajitha Biju, Sigfredo Fuentes, Dorin Gupta
Silicon (Si) has been widely reported to have beneficial effect on mitigating drought stress in plants. However, the effect of Si on seed germination under drought conditions is still poorly understood. This research was carried out to ascertain the role of Si to abate polyethylene glycol-6000 mediated drought stress on seed germination and seedling growth of lentil. Results showed that drought stress significantly decreased the seed germination traits and increased the concentration of osmolytes (proline, glycine betaine and soluble sugars), reactive oxygen species (hydrogen peroxide and superoxide anion) and lipid peroxides in lentil seedlings...
September 5, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28913528/dna-protection-by-ectoine-from-ionizing-radiation-molecular-mechanisms
#3
Marc Benjamin Hahn, Susann Meyer, Maria-Astrid Schröter, Hans-Jörg Kunte, Tihomir Solomun, Heinz Sturm
Ectoine, a compatible solute and osmolyte, is known to be an effective protectant of biomolecules and whole cells against heating, freezing and extreme salinity. Protection of cells (human keratinocytes) by ectoine against ultraviolet radiation has also been reported by various authors, although the underlying mechanism is not yet understood. We present the first electron irradiation of DNA in a fully aqueous environment in the presence of ectoine and at high salt concentrations. The results demonstrate effective protection of DNA by ectoine against the induction of single-strand breaks by ionizing radiation...
September 15, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28910985/yeast-bacteria-competition-induced-new-metabolic-traits-through-large-scale-genomic-rearrangements-in-lachancea-kluyveri
#4
Nerve Zhou, Samuele Bottagisi, Michael Katz, Joseph Schacherer, Anne Friedrich, Zoran Gojkovic, Krishna B S Swamy, Wolfgang Knecht, Concetta Compagno, Jure Piškur
Large-scale chromosomal rearrangements are an important source of evolutionary novelty that may have reshaped the genomes of existing yeast species. They dramatically alter genome organization and gene expression fueling a phenotypic leap in response to environmental constraints. Although the emergence of such signatures of genetic diversity is thought to be associated with human exploitation of yeasts, less is known about the driving forces operating in natural habitats. Here we hypothesize that an ecological battlefield characteristic of every autumn when fruits ripen accounts for the genomic innovations in natural populations...
September 1, 2017: FEMS Yeast Research
https://www.readbyqxmd.com/read/28906027/sur1-trpm4-and-aqp4-form-a-heteromultimeric-complex-that-amplifies-ion-water-osmotic-coupling-and-drives-astrocyte-swelling
#5
Jesse A Stokum, Min S Kwon, Seung K Woo, Orest Tsymbalyuk, Rudi Vennekens, Volodymyr Gerzanich, J Marc Simard
Astrocyte swelling occurs after central nervous system injury and contributes to brain swelling, which can increase mortality. Mechanisms proffered to explain astrocyte swelling emphasize the importance of either aquaporin-4 (AQP4), an astrocyte water channel, or of Na(+) -permeable channels, which mediate cellular osmolyte influx. However, the spatio-temporal functional interactions between AQP4 and Na(+) -permeable channels that drive swelling are poorly understood. We hypothesized that astrocyte swelling after injury is linked to an interaction between AQP4 and Na(+) -permeable channels that are newly upregulated...
September 14, 2017: Glia
https://www.readbyqxmd.com/read/28905119/jasmonic-acid-induced-tolerance-to-root-knot-nematodes-in-tomato-plants-through-altered-photosynthetic-and-antioxidative-defense-mechanisms
#6
Shagun Bali, Parminder Kaur, Anket Sharma, Puja Ohri, Renu Bhardwaj, M N Alyemeni, Leonard Wijaya, Parvaiz Ahmad
Plant parasitic nematodes cause severe damage to cultivated crops globally. Management of nematode population is a major concern as chemicals used as nematicides have negative impact on the environment. Natural plant products can be safely used for the control of nematodes. Among various plant metabolites, plant hormones play an essential role in developmental and physiological processes and also assist the plants to encounter stressful conditions. Keeping this in mind, the present study was designed to evaluate the effect of jasmonic acid (JA) on the growth, pigments, polyphenols, antioxidants, osmolytes, and organic acids under nematode infection in tomato seedlings...
September 13, 2017: Protoplasma
https://www.readbyqxmd.com/read/28900731/selenium-mitigates-cadmium-induced-oxidative-stress-in-tomato-solanum-lycopersicum-l-plants-by-modulating-chlorophyll-fluorescence-osmolyte-accumulation-and-antioxidant-system
#7
Mohammed Nasser Alyemeni, Mohammad Abass Ahanger, Leonard Wijaya, Pravej Alam, Renu Bhardwaj, Parvaiz Ahmad
Pot experiments were conducted to investigate the role of selenium in alleviating cadmium stress in Solanum lycopersicum seedlings. Cadmium (150 mg L(-1)) treatment caused a significant reduction in growth in terms of height and biomass accumulation and affected chlorophyll pigments, gas exchange parameters, and chlorophyll fluorescence. Selenium (10 μM) application mitigated the adverse effects of cadmium on growth, chlorophyll and carotenoid contents, leaf relative water content, and other physiological attributes...
September 12, 2017: Protoplasma
https://www.readbyqxmd.com/read/28900441/bacillus-amyloliquefaciens-confers-tolerance-to-various-abiotic-stresses-and-modulates-plant-response-to-phytohormones-through-osmoprotection-and-gene-expression-regulation-in-rice
#8
Shalini Tiwari, Vivek Prasad, Puneet S Chauhan, Charu Lata
Being sessile in nature, plants have to withstand various adverse environmental stress conditions including both biotic and abiotic stresses. Comparatively, abiotic stresses such as drought, salinity, high temperature, and cold pose major threat to agriculture by negatively impacting plant growth and yield worldwide. Rice is one of the most widely consumed staple cereals across the globe, the production and productivity of which is also severely affected by different abiotic stresses. Therefore, several crop improvement programs are directed toward developing stress tolerant rice cultivars either through marker assisted breeding or transgenic technology...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28895882/physiological-and-transcriptomic-responses-of-chinese-cabbage-brassica-rapa-l-ssp-pekinensis-to-salt-stress
#9
Nianwei Qiu, Qian Liu, Jingjuan Li, Yihui Zhang, Fengde Wang, Jianwei Gao
Salt stress is one of the major abiotic stresses that severely impact plant growth and development. In this study, we investigated the physiological and transcriptomic responses of Chinese cabbage "Qingmaye" to salt stress, a main variety in North China. Our results showed that the growth and photosynthesis of Chinese cabbage were significantly inhibited by salt treatment. However, as a glycophyte, Chinese cabbage could cope with high salinity; it could complete an entire life cycle at 100 mM NaCl. The high salt tolerance of Chinese cabbage was achieved by accumulating osmoprotectants and by maintaining higher activity of antioxidant enzymes...
September 12, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28895647/sliding-doors-heteromeric-volume-sensitive-osmolyte-channels
#10
Ian H Lambert
Release of the organic osmolyte taurine from mammalian cells following osmotic cell swelling, impacts not only cell volume but also cellular membrane dynamics, antioxidative capacity, metabolism, as well as apoptotic progression. This article is protected by copyright. All rights reserved.
September 12, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28894456/effects-of-combined-low-glutathione-with-mild-oxidative-and-low-phosphorus-stress-on-the-metabolism-of-arabidopsis-thaliana
#11
Atsushi Fukushima, Mami Iwasa, Ryo Nakabayashi, Makoto Kobayashi, Tomoko Nishizawa, Yozo Okazaki, Kazuki Saito, Miyako Kusano
Plants possess highly sensitive mechanisms that monitor environmental stress levels for a dose-dependent fine-tuning of their growth and development. Differences in plant responses to severe and mild abiotic stresses have been recognized. Although many studies have revealed that glutathione can contribute to plant tolerance to various environmental stresses, little is known about the relationship between glutathione and mild abiotic stress, especially the effect of stress-induced altered glutathione levels on the metabolism...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28881317/modulation-of-antioxidative-defense-expression-and-osmolyte-content-by-co-application-of-24-epibrassinolide-and-salicylic-acid-in-pb-exposed-indian-mustard-plants
#12
Sukhmeen Kaur Kohli, Neha Handa, Shagun Bali, Saroj Arora, Anket Sharma, Ravdeep Kaur, Renu Bhardwaj
The study focuses on potential of combined pre-soaking treatment of 24-Epibrassinolide (EBL) and Salicylic acid (SA) in alleviating Pb phytotoxicity in Brassica juncea L. plants. The seeds after treatment with combination of both the hormones were sown in mixture of soil, sand and manure (3:1:1) and were exposed to Pb concentrations (0.25mM, 0.50mM and 0.75mM). After 30 days of growth, the plants were harvested and processed, for quantification of various metabolites. It was found that pre-sowing of seeds in combination of EBL and SA, mitigated the adverse effects of metal stress by modulating antioxidative defense response and enhanced osmolyte contents...
September 4, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28878796/autophagy-is-rapidly-induced-by-salt-stress-and-is-required-for-salt-tolerance-in-arabidopsis
#13
Liming Luo, Pingping Zhang, Ruihai Zhu, Jing Fu, Jing Su, Jing Zheng, Ziyue Wang, Dan Wang, Qingqiu Gong
Salinity stress challenges agriculture and food security globally. Upon salt stress, plant growth slows down, nutrients are recycled, osmolytes are produced, and reallocation of Na(+) takes place. Since autophagy is a high-throughput degradation pathway that contributes to nutrient remobilization in plants, we explored the involvement of autophagic flux in salt stress response of Arabidopsis with various approaches. Confocal microscopy of GFP-ATG8a in transgenic Arabidopsis showed that autophagosome formation is induced shortly after salt treatment...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28878329/rna-sequencing-and-co-expressed-long-non-coding-rna-in-modern-and-wild-wheats
#14
Halise Busra Cagirici, Burcu Alptekin, Hikmet Budak
There is an urgent need for the improvement of drought-tolerant bread and durum wheat. The huge and complex genome of bread wheat (BBAADD genome) stands as a vital obstruction for understanding the molecular mechanism underlying drought tolerance. However, tetraploid wheat (Triticum turgidum ssp., BBAA genome) is an ancestor of modern bread wheat and offers an important model for studying the drought response due to its less complex genome. Additionally, several wild relatives of tetraploid wheat have already shown a significant drought tolerance...
September 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28875293/nickel-accumulation-and-its-effect-on-growth-physiological-and-biochemical-parameters-in-millets-and-oats
#15
Vibha Gupta, Pradeep Kumar Jatav, Raini Verma, Shanker Lal Kothari, Sumita Kachhwaha
With the boom in industrialization, there is an increase in the level of heavy metals in the soil which drastically affect the growth and development of plants. Nickel is an essential micronutrient for plant growth and development, but elevated level of Ni causes stunted growth, chlorosis, nutrient imbalance, and alterations in the defense mechanism of plants in terms of accumulation of osmolytes or change in enzyme activities like guiacol peroxidase (POD), catalase (CAT), and superoxide dismutase (SOD). Ni-induced toxic response was studied in seedlings of finger millet, pearl millet, and oats in terms of seedling growth, lipid peroxidation, total chlorophyll, proline content, and enzymatic activities...
September 5, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28874508/aba-induced-stomatal-closure-involves-almt4-a-phosphorylation-dependent-vacuolar-anion-channel-of-arabidopsis
#16
Cornelia Eisenach, Ulrike Baetz, Nicola V Huck, Jingbo Zhang, Alexis De Angeli, Gerold Beckers, Enrico Martinoia
Stomatal pores are formed between a pair of guard cells, and allow plant uptake of CO2 and water evaporation. Their aperture depends on changes in osmolyte concentration of guard cell vacuoles, specifically of K+ and Mal2-. Efflux of Mal2- from the vacuole is required for stomatal closure; however, it is not clear how the anion is released. Here we report the identification of ALMT4 (ALUMINIUM ACTIVATED MALATE TRANSPORTER 4) as an Arabidopsis thaliana ion channel that can mediate Mal2- release from the vacuole and is required for stomatal closure in response to abscisic acid (ABA)...
September 5, 2017: Plant Cell
https://www.readbyqxmd.com/read/28861106/unraveling-salt-tolerance-mechanisms-in-halophytes-a-comparative-study-on-four-mediterranean-limonium-species-with-different-geographic-distribution-patterns
#17
Mohamad Al Hassan, Elena Estrelles, Pilar Soriano, María P López-Gresa, José M Bellés, Monica Boscaiu, Oscar Vicente
We have performed an extensive study on the responses to salt stress in four related Limonium halophytes with different geographic distribution patterns, during seed germination and early vegetative growth. The aims of the work were twofold: to establish the basis for the different chorology of these species, and to identify relevant mechanisms of salt tolerance dependent on the control of ion transport and osmolyte accumulation. Seeds were germinated in vitro, in the presence of increasing NaCl concentrations, and subjected to "recovery of germination" tests; germination percentages and velocity were determined to establish the relative tolerance and competitiveness of the four Limonium taxa...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28835914/the-role-of-floridoside-in-osmoadaptation-of-coral-associated-algal-endosymbionts-to-high-salinity-conditions
#18
Michael A Ochsenkühn, Till Röthig, Cecilia D'Angelo, Jörg Wiedenmann, Christian R Voolstra
The endosymbiosis between Symbiodinium dinoflagellates and stony corals provides the foundation of coral reef ecosystems. The survival of these ecosystems is under threat at a global scale, and better knowledge is needed to conceive strategies for mitigating future reef loss. Environmental disturbance imposing temperature, salinity, and nutrient stress can lead to the loss of the Symbiodinium partner, causing so-called coral bleaching. Some of the most thermotolerant coral-Symbiodinium associations occur in the Persian/Arabian Gulf and the Red Sea, which also represent the most saline coral habitats...
August 2017: Science Advances
https://www.readbyqxmd.com/read/28833202/molecular-composition-and-heterogeneity-of-the-lrrc8-containing-swelling-activated-osmolyte-channels-in-primary-rat-astrocytes
#19
Alexandra L Schober, Corinne S Wilson, Alexander A Mongin
Volume-regulated anion channel (VRAC) is the ubiquitously expressed vertebrate Cl(-) /anion channel that is comprised of proteins belonging to the LRRC8 family and activated by cell swelling. In the brain, VRAC contributes to physiological and pathological release of a variety of small organic molecules, including the amino acid neurotransmitters glutamate, aspartate, and taurine. In the present work, we explored the role of all five LRRC8 family members in the release of organic osmolytes from primary rat astrocytes...
August 22, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28828605/taurine-homeostasis-and-volume-control
#20
Herminia Pasantes-Morales
Taurine content is high (mM) in mammalian brain. By its major role as an osmolyte, taurine contributes to the cell volume control, which is particularly critical in the brain. Taurine participates in osmotic adjustments required to maintain the organization and size of intracellular compartments. It counteracts volume fluctuations in unbalanced transmembrane fluxes of ions and neurotransmitters, preserving the functional synaptic contacts. Taurine has a key role in the long-term adaptation to chronic hyponatremia as well as in other pathologies leading to brain edema...
2017: Advances in Neurobiology
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