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https://www.readbyqxmd.com/read/28099884/characterization-of-human-and-staphylococcus-aureus-proteins-in-respiratory-mucosa-by-in-vivo-and-immunoproteomics
#1
Frank Schmidt, Tanja Meyer, Nandakumar Sundaramoorthy, Stephan Michalik, Kristin Surmann, Maren Depke, Vishnu Dhople, Manuela Gesell Salazar, Gabriele Holtappels, Nan Zhang, Barbara M Bröker, Claus Bachert, Uwe Völker
: Staphylococcus aureus is a Gram-positive opportunistic bacterium which can be found as a commensal in the nares of about 50% of the human population. Besides asymptomatic carriage, S. aureus has also been found to colonize nasal polyps, a subform of chronic rhinosinusitis, in 60 to 100% of cases, and even reside intracellularly in nasal polyp tissue. The aim of this study was to shed light on the behavior of S. aureus in the human airways by analyzing S. aureus-specific proteins in nasal polyp tissue from patients with chronic rhinosinusitis and to characterize the immunogenic potential of the identified (mainly secreted) proteins...
January 15, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28072463/pilot-study-of-mobile-phone-technology-in-allergic-rhinitis-in-european-countries-the-mask-rhinitis-study
#2
J Bousquet, D P Caimmi, A Bedbrook, M Bewick, P W Hellings, P Devillier, S Arnavielhe, C Bachert, K C Bergmann, G W Canonica, N Chavannes, A A Cruz, R Dahl, P Demoly, G De Vries, E Mathieu-Dupas, A Fink Wagner, J Fonseca, N Guldemond, T Haahtela, B Hellqvist-Dahl, J Just, T Keil, L Klimek, M L Kowalski, M Kuitunen, P Kuna, V Kvedariene, D Laune, A M Pereira, P Carreiro-Martins, E Melén, M Morais-Almeida, J Mullol, A Muraro, R Murray, L Nogueira-Silva, N G Papadopoulos, G Passalacqua, F Portejoie, D Price, D Ryan, B Samolinski, A Sheikh, V Siroux, O Spranger, A Todo Bom, P V Tomazic, A Valero, E Valovirta, A Valiulis, O VandenPlas, S van der Meulen, M van Eerd, M Wickman, T Zuberbier
BACKGROUND: The use of Apps running on smartphones and tablets profoundly affects medicine. The MASK-rhinitis (MACVIA-ARIA Sentinel NetworK for allergic rhinitis) App (Allergy Diary) assesses allergic rhinitis symptoms, disease control and impact on patients' lives. It is freely available in 20 countries (iOS and Android platforms). AIMS: To assess in a pilot study whether (i) Allergy Diary users were able to properly provide baseline characteristics (ii) simple phenotypic characteristics based upon data captured by the Allergy Diary could be identified and (iii) information gathered by this study could suggest novel research questions...
January 10, 2017: Allergy
https://www.readbyqxmd.com/read/27999855/building-bridges-for-innovation-in-ageing-synergies-between-action-groups-of-the-eip-on-aha
#3
J Bousquet, M Bewick, A Cano, P Eklund, G Fico, N Goswami, N A Guldemond, D Henderson, M J Hinkema, G Liotta, A Mair, W Molloy, A Monaco, I Monsonis-Paya, A Nizinska, H Papadopoulos, A Pavlickova, S Pecorelli, A Prados-Torres, R E Roller-Wirnsberger, D Somekh, C Vera-Muñoz, F Visser, J Farrell, J Malva, K Andersen Ranberg, T Camuzat, A M Carriazo, G Crooks, Z Gutter, G Iaccarino, E Manuel de Keenoy, G Moda, L Rodriguez-Mañas, T Vontetsianos, C Abreu, J Alonso, C Alonso-Bouzon, J Ankri, M T Arredondo, F Avolio, A Bedbrook, A Z Białoszewski, H Blain, R Bourret, M F Cabrera-Umpierrez, A Catala, R O'Caoimh, M Cesari, N H Chavannes, J Correia-da-Sousa, T Dedeu, M Ferrando, M Ferri, W J Fokkens, F Garcia-Lizana, O Guérin, P W Hellings, T Haahtela, M Illario, M C Inzerilli, K C Lodrup Carlsen, P Kardas, T Keil, M Maggio, A Mendez-Zorrilla, E Menditto, J Mercier, J P Michel, R Murray, M Nogues, I O'Byrne-Maguire, D Pappa, A S Parent, M Pastorino, C Robalo-Cordeiro, B Samolinski, P Siciliano, A M Teixeira, S I Tsartara, A Valiulis, O Vandenplas, T Vasankari, B Vellas, M Vollenbroek-Hutten, M Wickman, A Yorgancioglu, T Zuberbier, M Barbagallo, G W Canonica, L Klimek, S Maggi, W Aberer, C Akdis, I M Adcock, I Agache, C Albera, F Alonso-Trujillo, M Angel Guarcia, I Annesi-Maesano, J Apostolo, S H Arshad, V Attalin, A Avignon, C Bachert, I Baroni, E Bel, M Benson, C Bescos, F Blasi, C Barbara, K C Bergmann, P L Bernard, S Bonini, P J Bousquet, B Branchini, C E Brightling, V Bruguière, C Bunu, A Bush, D P Caimmi, M A Calderon, G Canovas, V Cardona, K H Carlsen, A Cesario, E Chkhartishvili, R Chiron, T Chivato, K F Chung, M d'Angelantonio, G De Carlo, D Cholley, F Chorin, B Combe, B Compas, D J Costa, E Costa, O Coste, A-L Coupet, G Crepaldi, A Custovic, R Dahl, S E Dahlen, P Demoly, P Devillier, A Didier, A T Dinh-Xuan, R Djukanovic, D Dokic, G Du Toit, R Dubakiene, A Dupeyron, R Emuzyte, A Fiocchi, A Wagner, M Fletcher, J Fonseca, B Fougère, A Gamkrelidze, G Garces, J Garcia-Aymeric, B Garcia-Zapirain, B Gemicioğlu, C Gouder, B Hellquist-Dahl, I Hermosilla-Gimeno, D Héve, C Holland, M Humbert, M Hyland, S L Johnston, J Just, M Jutel, I P Kaidashev, M Khaitov, O Kalayci, A F Kalyoncu, W Keijser, H Kerstjens, J Knezović, M Kowalski, G H Koppelman, T Kotska, M Kovac, I Kull, P Kuna, V Kvedariene, V Lepore, W MacNee, M Maggio, A Magnan, I Majer, P Manning, M Marcucci, T Marti, M Masoli, E Melen, N Miculinic, F Mihaltan, B Milenkovic, J Millot-Keurinck, H Mlinarić, I Momas, S Montefort, M Morais-Almeida, T Moreno-Casbas, R Mösges, J Mullol, R Nadif, M Nalin, E Navarro-Pardo, K Nekam, G Ninot, D Paccard, S Pais, E Palummeri, P Panzner, N K Papadopoulos, C Papanikolaou, G Passalacqua, E Pastor, M Perrot, D Plavec, T A Popov, D S Postma, D Price, N Raffort, J C Reuzeau, J M Robine, F Rodenas, F Robusto, N Roche, A Romano, V Romano, J Rosado-Pinto, F Roubille, F Ruiz, D Ryan, T Salcedo, P Schmid-Grendelmeier, H Schulz, H J Schunemann, E Serrano, A Sheikh, M Shields, N Siafakas, N Scichilone, P Siciliano, I Skrindo, H A Smit, S Sourdet, E Sousa-Costa, O Spranger, T Sooronbaev, V Sruk, P J Sterk, A Todo-Bom, J Touchon, D Tramontano, M Triggiani, S I Tsartara, A L Valero, E Valovirta, E van Ganse, M van Hage, M van den Berge, O Vandenplas, M T Ventura, I Vergara, G Vezzani, D Vidal, G Viegi, M Wagemann, B Whalley, M Wickman, N Wilson, P K Yiallouros, M Žagar, A Zaidi, M Zidarn, E J Hoogerwerf, J Usero, R Zuffada, A Senn, B de Oliveira-Alves
The Strategic Implementation Plan of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) proposed six Action Groups. After almost three years of activity, many achievements have been obtained through commitments or collaborative work of the Action Groups. However, they have often worked in silos and, consequently, synergies between Action Groups have been proposed to strengthen the triple win of the EIP on AHA. The paper presents the methodology and current status of the Task Force on EIP on AHA synergies...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/27997716/collagen-like-proteins-of-pathogenic-streptococci
#4
REVIEW
Slawomir Lukomski, Beth A Bachert, Flavia Squeglia, Rita Berisio
The collagen domain, which is defined by the presence of the Gly-X-Y triplet repeats, is amongst the most versatile and widespread known structures found in proteins from organisms representing all three domains of life. The streptococcal collagen-like (Scl) proteins are widely present in pathogenic streptococci, including Streptococcus pyogenes, S. agalactiae, S. pneumoniae, and S. equi. Experiments and bioinformatic analyses support the hypothesis that all Scl proteins are homotrimeric and cell wall-anchored...
December 20, 2016: Molecular Microbiology
https://www.readbyqxmd.com/read/27931279/mp-azeflu-provides-rapid-and-effective-allergic-rhinitis-control-in-real-life-a-pan-european-study
#5
Ludger Klimek, Claus Bachert, Par Stjrne, Ralph Dollner, Petter Larsen, Peter Haahr, Ioana Agache, Glenis Scadding, David Price
BACKGROUND: The European Union has prioritized allergic rhinitis (AR) control. Contre les Maladies Chronique pour un Vieillissement Actif Allergic Rhinitis and its Impact on Asthma has endorsed the visual analog scale (VAS) as the AR control language and incorporated it into a new AR treatment algorithm. Concurrently, the Respiratory Effectiveness Group and the European Academy of Allergy and Clinical Immunology are striving to improve the quality of published real-life AR research. Our aim was to assess the effectiveness of MP-AzeFlu by using a VAS in a well-designed, real-life, pan-European study...
September 2016: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/27895895/allergy-immunotherapy-across-the-life-cycle-to-promote-active-and-healthy-ageing-from-research-to-policies-an-airways-integrated-care-pathways-icps-programme-item-action-plan-b3-of-the-european-innovation-partnership-on-active-and-healthy-ageing-and-the-global
#6
REVIEW
M A Calderon, P Demoly, T Casale, C A Akdis, C Bachert, M Bewick, B M Bilò, B Bohle, S Bonini, A Bush, D P Caimmi, G W Canonica, V Cardona, A M Chiriac, L Cox, A Custovic, F De Blay, P Devillier, A Didier, G Di Lorenzo, G Du Toit, S R Durham, P Eng, A Fiocchi, A T Fox, R Gerth van Wijk, R M Gomez, T Haathela, S Halken, P W Hellings, L Jacobsen, J Just, L K Tanno, J Kleine-Tebbe, L Klimek, E F Knol, P Kuna, D E Larenas-Linnemann, A Linneberg, M Matricardi, H J Malling, R Moesges, J Mullol, A Muraro, N Papadopoulos, G Passalacqua, E Pastorello, O Pfaar, D Price, P Rodriguez Del Rio, R Ruëff, B Samolinski, G K Scadding, G Senti, M H Shamji, A Sheikh, J C Sisul, D Sole, G J Sturm, A Tabar, R Van Ree, M T Ventura, C Vidal, E M Varga, M Worm, T Zuberbier, J Bousquet
Allergic diseases often occur early in life and persist throughout life. This life-course perspective should be considered in allergen immunotherapy. In particular it is essential to understand whether this al treatment may be used in old age adults. The current paper was developed by a working group of AIRWAYS integrated care pathways for airways diseases, the model of chronic respiratory diseases of the European Innovation Partnership on active and healthy ageing (DG CONNECT and DG Santé). It considered (1) the political background, (2) the rationale for allergen immunotherapy across the life cycle, (3) the unmet needs for the treatment, in particular in preschool children and old age adults, (4) the strategic framework and the practical approach to synergize current initiatives in allergen immunotherapy, its mechanisms and the concept of active and healthy ageing...
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/27891215/hypothesis-may-e-cigarette-smoking-boost-the-allergic-epidemic
#7
EDITORIAL
Jean Bousquet, Claus Bachert, Laura Crotty Alexander, Frank T Leone
No abstract text is available yet for this article.
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/27871865/iterative-reconstruction-of-radially-sampled-31-p-bssfp-data-using-prior-information-from-1-h-mri
#8
Kristian Rink, Nadia Benkhedah, Moritz C Berger, Christine Gnahm, Nicolas G R Behl, Jonathan M Lommen, Vanessa Stahl, Peter Bachert, Mark E Ladd, Armin M Nagel
The purpose of this study is to improve direct phosphorus ((31)P) MR imaging. Therefore, 3D density-adapted radially-sampled balanced steady-state free precession (bSSFP) sequences were developed and an iterative approach exploiting additional anatomical information from hydrogen ((1)H) data was evaluated. Three healthy volunteers were examined at B0=7T in order to obtain the spatial distribution of the phosphocreatine (PCr) intensities in the human calf muscle with a nominal isotropic resolution of 10mm in an acquisition time of 10min...
November 19, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27859838/aggregation-induced-changes-in-the-chemical-exchange-saturation-transfer-cest-signals-of-proteins
#9
Steffen Goerke, Katharina S Milde, Raul Bukowiecki, Patrick Kunz, Karel D Klika, Thomas Wiglenda, Axel Mogk, Erich E Wanker, Bernd Bukau, Mark E Ladd, Peter Bachert, Moritz Zaiss
Chemical exchange saturation transfer (CEST) is an MRI technique that allows mapping of biomolecules (small metabolites, proteins) with nearly the sensitivity of conventional water proton MRI. In living organisms, several tissue-specific CEST effects have been observed and successfully applied to diagnostic imaging. In these studies, particularly the signals of proteins showed a distinct correlation with pathological changes. However, as CEST effects depend on various properties that determine and affect the chemical exchange processes, the origins of the observed signal changes remain to be understood...
January 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/27817798/advances-in-rhinitis-and-rhinosinusitis-in-2015
#10
REVIEW
Claus Bachert, Elien Gevaert
The last year has seen great progress in the understanding of upper airway disease and in its management. For allergic rhinitis, authors focused on the prediction of and effect on the natural course of disease. New evidence was published for the disease-modifying effect of allergen immunotherapy in terms of avoidance of new sensitizations and prevention of asthma in either randomized or real-life studies. Specifically, for patients with house dust mite allergies, which are often underestimated and difficult to diagnose, the efficacy of SQ house dust mite sublingual immunotherapy tablets has been demonstrated in patients with allergic rhinitis and asthma...
November 2016: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27770460/alcohol-hyper-responsiveness-in-chronic-rhinosinusitis-with-nasal-polyps
#11
Els De Schryver, Lara Derycke, Paloma Campo, Eline Gabriels, Guy F Joos, Thibaut Van Zele, Claus Bachert, Peter W Hellings, Philippe Gevaert
BACKGROUND: An important percentage of subjects diagnosed with chronic upper airway disease report alcohol-induced worsening of their symptoms. The prevalence and characteristics of respiratory reactions provoked by alcohol-containing drinks has not been fully investigated yet. OBJECTIVE: The aim of this study was to estimate the prevalence and characteristics of alcohol hyper-responsiveness in patients with chronic airway disease and healthy controls. Furthermore, nasal inflammation was evaluated in nasal polyp patients with and without hyper-responsiveness...
October 22, 2016: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27697498/validation-of-the-ga-2-len-chamber-for-trials-in-allergy-innovation-of-a-mobile-allergen-exposure-chamber
#12
Torsten Zuberbier, Mark B Abelson, Cezmi A Akdis, Claus Bachert, Uwe Berger, Carsten Bindslev-Jensen, Georg Boelke, Jean Bousquet, Giorgio Walter Canonica, Thomas B Casale, Marek Jutel, Marek L Kowalski, Enzo Madonini, Nikolaos G Papadopoulos, Oliver Pfaar, Torsten Sehlinger, Karl-Christian Bergmann
BACKGROUND: Field clinical trials of pollen allergy are impacted by the impossibility to predict and to determine individual allergen exposure, due to many factors (e.g., pollen season, atmospheric variations, pollutants, lifestyles). Environmental exposure chambers (EEC), delivering a fixed amount of allergens in a controlled environmental setting, can overcome these limitations. EECs are currently already used in phase 2, 3, and even 4 trials. Unfortunately, few chambers exist in the world, and this makes it difficult to perform large, multicenter clinical trials...
September 30, 2016: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27695877/-when-a-name-becomes-a-unit-nikola-tesla
#13
G van Kaick, P Bachert
No abstract text is available yet for this article.
September 30, 2016: Der Radiologe
https://www.readbyqxmd.com/read/27632006/activity-detection-of-galnac-transferases-by-protein-based-fluorescence-sensors-in-vivo
#14
Lina Song, Collin Bachert, Adam D Linstedt
Mucin-type O-glycosylation occurring in the Golgi apparatus is an important protein posttranslational modification initiated by up to 20 GalNAc-transferase isozymes with largely distinct substrate specificities. Regulation of this enzyme family affects a vast array of proteins transiting the secretory pathway and misregulation causes human diseases. Here we describe the use of protein-based fluorescence sensors that traffic in the secretory pathway to monitor GalNAc-transferase activity in living cells. The sensors can either be "pan" or isozyme specific...
2016: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27630827/unique-footprint-in-the-scl1-3-locus-affects-adhesion-and-biofilm-formation-of-the-invasive-m3-type-group-a-streptococcus
#15
Beth A Bachert, Soo J Choi, Paul R LaSala, Tiffany I Harper, Dudley H McNitt, Dylan T Boehm, Clayton C Caswell, Pawel Ciborowski, Douglas R Keene, Anthony R Flores, James M Musser, Flavia Squeglia, Daniela Marasco, Rita Berisio, Slawomir Lukomski
The streptococcal collagen-like proteins 1 and 2 (Scl1 and Scl2) are major surface adhesins that are ubiquitous among group A Streptococcus (GAS). Invasive M3-type strains, however, have evolved two unique conserved features in the scl1 locus: (i) an IS1548 element insertion in the scl1 promoter region and (ii) a nonsense mutation within the scl1 coding sequence. The scl1 transcript is drastically reduced in M3-type GAS, contrasting with a high transcription level of scl1 allele in invasive M1-type GAS. This leads to a lack of Scl1 expression in M3 strains...
2016: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/27558820/immunogenic-apoptotic-cell-death-and-anticancer-immunity
#16
Peter Vandenabeele, Katrien Vandecasteele, Claus Bachert, Olga Krysko, Dmitri V Krysko
For many years it has been thought that apoptotic cells rapidly cleared by phagocytic cells do not trigger an immune response but rather have anti-inflammatory properties. However, accumulating experimental data indicate that certain anticancer therapies can induce an immunogenic form of apoptosis associated with the emission of damage-associated molecular patterns (DAMPs), which function as adjuvants to activate host antitumor immune responses. In this review, we will first discuss recent advances and the significance of danger signaling pathways involved in the emission of DAMPs, including calreticulin, ATP, and HMGB1...
2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27544740/diversity-of-th-cytokine-profiles-in-patients-with-chronic-rhinosinusitis-a%C3%A2-multicenter-study-in-europe-asia-and-oceania
#17
Xiangdong Wang, Nan Zhang, Mingyu Bo Ms, Gabriele Holtappels, Ming Zheng, Hongfei Lou, Hong Wang, Luo Zhang, Claus Bachert
BACKGROUND: To date, no study has evaluated the diversity of TH cell cytokine patterns of patients with chronic rhinosinusitis (CRS) among centers in different continents using identical methods. OBJECTIVE: We sought to assess TH cytokine profiles in patients with CRS from Europe, Asia, and Australia. METHODS: Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) and without nasal polyps (CRSsNP; n = 435) and control subjects (n = 138) were recruited from centers in Adelaide, Benelux, Berlin, Beijing, Chengdu, and Tochigi...
July 15, 2016: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27521026/adiabatically-prepared-spin-lock-approach-for-t1%C3%AF-based-dynamic-glucose-enhanced-mri-at-ultrahigh-fields
#18
Patrick Schuenke, Christina Koehler, Andreas Korzowski, Johannes Windschuh, Peter Bachert, Mark E Ladd, Sibu Mundiyanapurath, Daniel Paech, Sebastian Bickelhaupt, David Bonekamp, Heinz-Peter Schlemmer, Alexander Radbruch, Moritz Zaiss
PURPOSE: Chemical exchange sensitive spin-lock and related techniques allow to observe the uptake of administered D-glucose in vivo. The exchange-weighting increases with the magnetic field strength, but inhomogeneities in the radiofrequency (RF) field at ultrahigh field whole-body scanners lead to artifacts in conventional spin-lock experiments. Thus, our aim was the development of an adiabatically prepared T1ρ -based imaging sequence applicable to studies of glucose metabolism in tumor patients at ultrahigh field strengths...
August 13, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27500993/rupatadine-global-safety-evaluation-in-allergic-rhinitis-and-urticaria
#19
Vanesa González-Núñez, Claus Bachert, Joaquim Mullol
INTRODUCTION: Rupatadine is a second-generation H1-antihistamine with dual affinity for histamine H1 and PAF receptors. Rupatadine is indicated for the treatment of allergic rhinitis and urticaria. AREAS COVERED: A Medline search was conducted to identify preclinical and clinical studies of rupatadine. This was supplemented with additional articles obtained from online sources. The focus of this review is on the safety profile of rupatadine. EXPERT OPINION: The review of these data indicates that rupatadine is highly selective for histamine H1-receptors, exhibits additional PAF antagonism in in vitro and in vivo studies, does not cross the blood-brain barrier, and has similar adverse events comparable with other second-generation antihistamines...
October 2016: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/27478588/scaling-up-strategies-of-the-chronic-respiratory-disease-programme-of-the-european-innovation-partnership-on-active-and-healthy-ageing-action-plan-b3-area-5
#20
REVIEW
J Bousquet, J Farrell, G Crooks, P Hellings, E H Bel, M Bewick, N H Chavannes, J Correia de Sousa, A A Cruz, T Haahtela, G Joos, N Khaltaev, J Malva, A Muraro, M Nogues, S Palkonen, S Pedersen, C Robalo-Cordeiro, B Samolinski, T Strandberg, A Valiulis, A Yorgancioglu, T Zuberbier, A Bedbrook, W Aberer, M Adachi, A Agusti, C A Akdis, M Akdis, J Ankri, A Alonso, I Annesi-Maesano, I J Ansotegui, J M Anto, S Arnavielhe, H Arshad, C Bai, I Baiardini, C Bachert, A K Baigenzhin, C Barbara, E D Bateman, B Beghé, A Ben Kheder, K S Bennoor, M Benson, K C Bergmann, T Bieber, C Bindslev-Jensen, L Bjermer, H Blain, F Blasi, A L Boner, M Bonini, S Bonini, S Bosnic-Anticevitch, L P Boulet, R Bourret, P J Bousquet, F Braido, A H Briggs, C E Brightling, J Brozek, R Buhl, P G Burney, A Bush, F Caballero-Fonseca, D Caimmi, M A Calderon, P M Calverley, P A M Camargos, G W Canonica, T Camuzat, K H Carlsen, W Carr, A Carriazo, T Casale, A M Cepeda Sarabia, L Chatzi, Y Z Chen, R Chiron, E Chkhartishvili, A G Chuchalin, K F Chung, G Ciprandi, I Cirule, L Cox, D J Costa, A Custovic, R Dahl, S E Dahlen, U Darsow, G De Carlo, F De Blay, T Dedeu, D Deleanu, E De Manuel Keenoy, P Demoly, J A Denburg, P Devillier, A Didier, A T Dinh-Xuan, R Djukanovic, D Dokic, H Douagui, G Dray, R Dubakiene, S R Durham, M S Dykewicz, Y El-Gamal, R Emuzyte, L M Fabbri, M Fletcher, A Fiocchi, A Fink Wagner, J Fonseca, W J Fokkens, F Forastiere, P Frith, M Gaga, A Gamkrelidze, J Garces, J Garcia-Aymerich, B Gemicioğlu, J E Gereda, S González Diaz, M Gotua, I Grisle, L Grouse, Z Gutter, M A Guzmán, L G Heaney, B Hellquist-Dahl, D Henderson, A Hendry, J Heinrich, D Heve, F Horak, J O' B Hourihane, P Howarth, M Humbert, M E Hyland, M Illario, J C Ivancevich, J R Jardim, E J Jares, C Jeandel, C Jenkins, S L Johnston, O Jonquet, K Julge, K S Jung, J Just, I Kaidashev, M R Kaitov, O Kalayci, A F Kalyoncu, T Keil, P K Keith, L Klimek, B Koffi N'Goran, V Kolek, G H Koppelman, M L Kowalski, I Kull, P Kuna, V Kvedariene, B Lambrecht, S Lau, D Larenas-Linnemann, D Laune, L T T Le, P Lieberman, B Lipworth, J Li, K Lodrup Carlsen, R Louis, W MacNee, Y Magard, A Magnan, B Mahboub, A Mair, I Majer, M J Makela, P Manning, S Mara, G D Marshall, M R Masjedi, P Matignon, M Maurer, S Mavale-Manuel, E Melén, E Melo-Gomes, E O Meltzer, A Menzies-Gow, H Merk, J P Michel, N Miculinic, F Mihaltan, B Milenkovic, G M Y Mohammad, M Molimard, I Momas, A Montilla-Santana, M Morais-Almeida, M Morgan, R Mösges, J Mullol, S Nafti, L Namazova-Baranova, R Naclerio, A Neou, H Neffen, K Nekam, B Niggemann, G Ninot, T D Nyembue, R E O'Hehir, K Ohta, Y Okamoto, K Okubo, S Ouedraogo, P Paggiaro, I Pali-Schöll, P Panzner, N Papadopoulos, A Papi, H S Park, G Passalacqua, I Pavord, R Pawankar, R Pengelly, O Pfaar, R Picard, B Pigearias, I Pin, D Plavec, D Poethig, W Pohl, T A Popov, F Portejoie, P Potter, D Postma, D Price, K F Rabe, F Raciborski, F Radier Pontal, S Repka-Ramirez, S Reitamo, S Rennard, F Rodenas, J Roberts, J Roca, L Rodriguez Mañas, C Rolland, M Roman Rodriguez, A Romano, J Rosado-Pinto, N Rosario, L Rosenwasser, M Rottem, D Ryan, M Sanchez-Borges, G K Scadding, H J Schunemann, E Serrano, P Schmid-Grendelmeier, H Schulz, A Sheikh, M Shields, N Siafakas, Y Sibille, T Similowski, F E R Simons, J C Sisul, I Skrindo, H A Smit, D Solé, T Sooronbaev, O Spranger, R Stelmach, P J Sterk, J Sunyer, C Thijs, T To, A Todo-Bom, M Triggiani, R Valenta, A L Valero, E Valia, E Valovirta, E Van Ganse, M van Hage, O Vandenplas, T Vasankari, B Vellas, J Vestbo, G Vezzani, P Vichyanond, G Viegi, C Vogelmeier, T Vontetsianos, M Wagenmann, B Wallaert, S Walker, D Y Wang, U Wahn, M Wickman, D M Williams, S Williams, J Wright, B P Yawn, P K Yiallouros, O M Yusuf, A Zaidi, H J Zar, M E Zernotti, L Zhang, N Zhong, M Zidarn, J Mercier
Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS integrated care pathways (ICPs), (2) the joint initiative between the Reference site MACVIA-LR (Contre les MAladies Chroniques pour un VIeillissement Actif) and ARIA (Allergic Rhinitis and its Impact on Asthma), (3) Commitments for Action to the European Innovation Partnership on Active and Healthy Ageing and the AIRWAYS ICPs network...
2016: Clinical and Translational Allergy
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