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https://www.readbyqxmd.com/read/28453719/civil-war-contested-sovereignty-and-the-limits-of-global-health-partnerships-a-case-study-of-the-syrian-polio-outbreak-in-2013
#1
Jonathan Kennedy, Domna Michailidou
States and the World Health Organization (WHO), an international organization that is mandated to respect the sovereignty of its member states, are still the leading actors in global health. This paper explores how this discrepancy inhibits the ability of global health partnerships to implement programmes in conflict-affected areas that are under the de facto control of rebel organizations. We concentrate on a single crucial case, the polio outbreak in Syria in 2013, analysing a variety of qualitative data-twenty semi-structured interviews with key actors, official documents, and media reports-in order to investigate the events that preceded and followed this event...
June 1, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28453714/evaluating-the-effect-of-integrated-microfinance-and-health-interventions-an-updated-review-of-the-evidence
#2
Lara M J Lorenzetti, Sheila Leatherman, Valerie L Flax
Background: Solutions delivered within firm sectoral boundaries are inadequate in achieving income security and better health for poor populations. Integrated microfinance and health interventions leverage networks of women to promote financial inclusion, build livelihoods, and safeguard against high cost illnesses. Our understanding of the effect of integrated interventions has been limited by variability in intervention, outcome, design, and methodological rigour. This systematic review synthesises the literature through 2015 to understand the effect of integrated microfinance and health programs...
June 1, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28453424/a-multicomponent-library-resource-model-to-enhance-academic-global-health-education-among-residency-programs
#3
Rupa R Patel, Sandhiya Ravichandran, Michelle M Doering, Angela C Hardi
Global health is becoming an increasingly important component of medical education. Medical libraries have an opportunity to assist global health residents with their information needs, but first it is important to identify what those needs are and how best they can be addressed. This article reports a collaboration between global health faculty and an academic medical librarian to assess the information needs of global health pathway residents and how assessment data are used to create a multicomponent program designed to enhance global health education...
April 2017: Medical Reference Services Quarterly
https://www.readbyqxmd.com/read/28448753/road-traffic-injury-in-sub-saharan-african-countries-a-systematic-review-and-summary-of-observational-studies
#4
João Ricardo N Vissoci, Daniel J Shogilev, Elizabeth Krebs, Luciano de Andrade, Igor Fiorese Vieira, Nicole Toomey, Adelia Portero Batilana, Michael Haglund, Catherine A Staton
OBJECTIVE: The aim of this study is to evaluate, through a systematic review of hospital based studies, the proportion of road traffic injuries and fatalities in SSA. METHODS: In accordance with PRISMA and MOOSE guidelines we searched the following electronic databases: PubMed, Embase, Africa-Wide Information, Global Health, and Web of Science. Articles were eligible if they measured proportion of RTIs in SSA by using hospital based studies. In addition, a reference and citation analysis was conducted as well as a data quality assessment...
April 27, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28448340/global-health-of-babies-and-children
#5
(no author information available yet)
No abstract text is available yet for this article.
May 2017: MCN. the American Journal of Maternal Child Nursing
https://www.readbyqxmd.com/read/28447957/trevor-mundel-president-of-the-gates-foundation-global-health-division
#6
Tony Kirby
No abstract text is available yet for this article.
May 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28446574/the-use-of-genexpert-remnants-for-drug-resistance-profiling-and-molecular-epidemiology-of-tuberculosis-in-libreville-gabon
#7
Amel Kévin Alame-Emane, Catherine Pierre-Audigier, Oriane Cordelia Aboumegone-Biyogo, Amandine Nzoghe-Mveang, Véronique Cadet-Daniel, Christophe Sola, Joël Fleury Djoba-Siawaya, Brigitte Gicquel, Howard E Takiff
Multidrug (MDR) and extensively drug resistant (XDR) Mycobacterium tuberculosis are major problems in global health. The GeneXpertMTB/RIF (Xpert) rapidly detects resistance to rifampicin (RIF-R), but detection of the additional resistance that defines MDR and XDR-TB, and for molecular epidemiology, specimen cultures and biosafe infrastructure are generally required. We sought to determine whether the remnants of sputa prepared for Xpert could be used directly to find mutations associated with drug resistance and for molecular epidemiology, and thus provide a precise characterization of MDR-TB cases in countries lacking BSL3 facilities for M...
April 26, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28446486/delayed-diagnosis-of-pulmonary-tuberculosis-in-a-13-year-old-malawian-boy
#8
Niall Johnston, Nichola Sandys
Childhood tuberculosis (TB) is a significant global health burden. There are more than 1 million new cases of childhood TB annually. Despite this, many national TB control programs largely focus on identification and treatment of smear positive adults. Early case detection is essential if childhood TB is to be controlled and eradicated.Delayed diagnosis of TB is associated with more advanced disease and worse treatment outcomes. Younger children who go undiagnosed for long periods are at risk of developing severe pulmonary and extrapulmonary disease, such as meningitis...
April 26, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28445222/development-of-an-hiv-postexposure-prophylaxis-pep-protocol-for-trainees-engaging-in-academic-global-health-experiences
#9
Gitanjli Arora, Risa M Hoffman
PROBLEM: Global health (GH) education programs have become increasingly common in U.S. medical schools and graduate medical education programs, with growing numbers of medical students, residents, and fellows participating in clinical experiences in settings with high HIV prevalence and limited resources. However, there are no guidelines for provision of HIV postexposure prophylaxis (PEP) to trainees engaging in these academic GH experiences. APPROACH: Faculty of the Global Health Education Programs (GHEP) at the David Geffen School of Medicine at UCLA and GH partner institutions recognized the need for PEP access for trainees engaged in GH experiences...
April 25, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28443274/the-guatemala-penn-partners-an-innovative-inter-institutional-model-for-scientific-capacity-building-healthcare-education-and-public-health
#10
Maria Alejandra Paniagua-Avila, Elizabeth Messenger, Caroline A Nelson, Erwin Calgua, Frances K Barg, Kent W Bream, Charlene Compher, Anthony J Dean, Sergio Martinez-Siekavizza, Victor Puac-Polanco, Therese S Richmond, Rudolf R Roth, Charles C Branas
Population health outcomes are directly related to robust public health programs, access to basic health services, and a well-trained health-care workforce. Effective health services need to systematically identify solutions, scientifically test these solutions, and share generated knowledge. The World Health Organization (WHO)'s Global Healthcare Workforce Alliance states that the capacity to perform research is an essential factor for well-functioning public health systems. Low- and middle-income countries have greater health-care worker shortages and lower research capacity than higher-income countries...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28442804/clinico-epidemiological-profile-of-patients-attending-suraksha-clinic-of-tertiary-care-hospital-of-north-india
#11
H S Banger, Anisha Sethi, Sita Malhotra, Suresh Kumar Malhotra, Tejinder Kaur
BACKGROUND: Sexually transmitted infections (STIs) are a global health problem. Trends of STIs vary from place to place depending on various epidemiological factors prevailing in that respective geographic area. AIMS AND OBJECTIVES: The present study was conducted to find the pattern and prevalence of different STIs out of total STI clinic attendees, to identify any change in the trend of STIs, various epidemiological factors, and behavior of individual diseases...
January 2017: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28442754/vector-competence-and-transovarial-transmission-of-two-aedes-aegypti-strains-to-zika-virus
#12
Chun-Xiao Li, Xiao-Xia Guo, Yong-Qiang Deng, Dan Xing, Ai-Juan Sun, Qin-Mei Liu, Qun Wu, Yan-de Dong, Ying-Mei Zhang, Heng-Duan Zhang, Wu-Chun Cao, Cheng-Feng Qin, Tong-Yan Zhao
Zika virus (ZIKV) has become a serious threat to global health since the outbreak in Brazil in 2015. Additional Chinese cases have continuously been reported since the first case of laboratory-confirmed ZIKV infection in China on 6 February 2016. Aedes aegypti is the most important vector for ZIKV. This study shows that two strains from China exhibit high levels of midgut infection and highly disseminated infection of salivary glands and ovaries. Both strains can transmit ZIKV to infant mice bitten by infectious mosquitoes...
April 26, 2017: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/28442607/n-methyl-d-aspartate-nmda-receptor-blockade-prevents-neuronal-death-induced-by-zika-virus-infection
#13
Vivian V Costa, Juliana L Del Sarto, Rebeca F Rocha, Flavia R Silva, Juliana G Doria, Isabella G Olmo, Rafael E Marques, Celso M Queiroz-Junior, Giselle Foureaux, Julia Maria S Araújo, Allysson Cramer, Ana Luíza C V Real, Lucas S Ribeiro, Silvia I Sardi, Anderson J Ferreira, Fabiana S Machado, Antônio C de Oliveira, Antônio L Teixeira, Helder I Nakaya, Danielle G Souza, Fabiola M Ribeiro, Mauro M Teixeira
Zika virus (ZIKV) infection is a global health emergency that causes significant neurodegeneration. Neurodegenerative processes may be exacerbated by N-methyl-d-aspartate receptor (NMDAR)-dependent neuronal excitoxicity. Here, we have exploited the hypothesis that ZIKV-induced neurodegeneration can be rescued by blocking NMDA overstimulation with memantine. Our results show that ZIKV actively replicates in primary neurons and that virus replication is directly associated with massive neuronal cell death. Interestingly, treatment with memantine or other NMDAR blockers, including dizocilpine (MK-801), agmatine sulfate, or ifenprodil, prevents neuronal death without interfering with the ability of ZIKV to replicate in these cells...
April 25, 2017: MBio
https://www.readbyqxmd.com/read/28441726/sodium-and-potassium-intake-in-healthy-adults-in-thessaloniki-greater-metropolitan-area-the-salt-intake-in-northern-greece-sing-study
#14
Eleni Vasara, Georgios Marakis, Joao Breda, Petros Skepastianos, Maria Hassapidou, Anthony Kafatos, Nikolaos Rodopaios, Alexandra A Koulouri, Francesco P Cappuccio
A reduction in population sodium (as salt) consumption is a global health priority, as well as one of the most cost-effective strategies to reduce the burden of cardiovascular disease. High potassium intake is also recommended to reduce cardiovascular disease. To establish effective policies for setting targets and monitoring effectiveness within each country, the current level of consumption should be known. Greece lacks data on actual sodium and potassium intake. The aim of the present study was therefore to assess dietary salt (using sodium as biomarker) and potassium intakes in a sample of healthy adults in northern Greece, and to determine whether adherence to a Mediterranean diet is related to different sodium intakes or sodium-to-potassium ratio...
April 22, 2017: Nutrients
https://www.readbyqxmd.com/read/28438406/coverage-and-determinants-of-childhood-immunization-in-nigeria-a-systematic-review-and-meta-analysis
#15
REVIEW
Davies Adeloye, Wura Jacobs, Ann O Amuta, Oluwatomisin Ogundipe, Oluwaseun Mosaku, Muktar A Gadanya, Gbolahan Oni
INTRODUCTION: The proportion of fully immunized children in Nigeria is reportedly low. There are concerns over national immunization data quality, with this possibly limiting country-wide response. We reviewed publicly available evidence on routine immunization across Nigeria to estimate national and zonal coverage of childhood immunization and associated determinants. METHODS: A systematic search of Medline, EMBASE, Global Health and African Journals Online (AJOL) was conducted...
April 21, 2017: Vaccine
https://www.readbyqxmd.com/read/28438177/responding-to-non-communicable-diseases-in-zambia-a-policy-analysis
#16
Mulenga M Mukanu, Joseph Mumba Zulu, Chrispin Mweemba, Wilbroad Mutale
BACKGROUND: Non-communicable diseases (NCDs) are an emerging global health concern. Reports have shown that, in Zambia, NCDs are also an emerging problem and the government has begun initiating a policy response. The present study explores the policy response to NCDs by the Ministry of Health in Zambia using the policy triangle framework of Walt and Gilson. METHODS: A qualitative approach was used for the study. Data collected through key informant interviews with stakeholders who were involved in the NCD health policy development process as well as review of key planning and policy documents were analysed using thematic analysis...
April 24, 2017: Health Research Policy and Systems
https://www.readbyqxmd.com/read/28437734/idf-diabetes-atlas-global-estimates-for-the-prevalence-of-diabetes-for-2015-and-2040
#17
K Ogurtsova, J D da Rocha Fernandes, Y Huang, U Linnenkamp, L Guariguata, N H Cho, D Cavan, J E Shaw, L E Makaroff
AIM: To produce current estimates of the national, regional and global impact of diabetes for 2015 and 2040. METHODS: A systematic literature review was conducted to identify data sources on the prevalence of diabetes from studies conducted in the period from 1990 to 2015. An analytic hierarchy process was used to select the most appropriate studies for each country, and estimates for countries without data were modelled using extrapolation from similar countries that had available data...
March 31, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28437091/speeding-up-early-drug-discovery-in-antiviral-research-a-fragment-based-in-silico-approach-for-the-design-of-virtual-anti-hepatitis-c-leads
#18
Alejandro Speck-Planche, M Natalia Dias Soeiro Cordeiro
Hepatitis C constitutes an unresolved global health problem. This infectious disease is caused by the hepatotropic hepatitis C virus (HCV), and it can lead to the occurrence of life-threatening medical conditions such as cirrhosis and liver cancer. Nowadays, major clinical concerns have arisen due to the appearance of multidrug resistance (MDR), and the side effects especially associated with long-term treatments. In this work, we report the first multitasking model for quantitative structure-biological effect relationships (mtk-QSBER), focused on the simultaneous exploration of anti-HCV activity and in vitro safety profiles related to the absorption, distribution, metabolism, elimination, and toxicity (ADMET)...
April 24, 2017: ACS Combinatorial Science
https://www.readbyqxmd.com/read/28434857/a-study-evaluating-the-postprandial-plasma-glucose-control-among-type-2-diabetes-patients-attending-a-teaching-hospital-in-malaysia
#19
REVIEW
Salwa Selim Ibrahim Abougalambou, Nahid Osman Ahmed, Ayman S Abougalambou
BACKGROUND AND OBJECTIVE: Type 2 DM is rapidly rising as a global health care problem that threatens to reach pandemic levels by 2030. Type 2 diabetes mellitus is a disease with no cure and chronic disease that results in major morbidity and mortality. The main objective of this study is to evaluate postprandial plasma glucose level and to determine factors affect on postprandial plasma glucose level among type 2 diabetes outpatients attending endocrinology clinics at Hospital Universiti Sains Malaysia, Teaching Hospital...
April 10, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28434196/role-of-gut-microbiota-bile-acids-and-their-crosstalk-in-the-effects-of-bariatric-surgery-on-obesity-and-type-2-diabetes
#20
Haijun Liu, Cheng Hu, Xueli Zhang, Weiping Jia
Type 2 diabetes mellitus is becoming increasingly prevalent worldwide and has become one of the greatest threats to global health. Bariatric surgery was initially designed to achieve weight loss and subsequently was noted to induce improvements or remission of type 2 diabetes. Currently, these bariatric operations such as Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are the most effective procedures for the treatment of obesity and type 2 diabetes mellitus worldwide. However, the specific mechanism mediating the beneficial effects of metabolic surgery has remained largely unknown...
April 23, 2017: Journal of Diabetes Investigation
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