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granulomatous mastitis

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https://www.readbyqxmd.com/read/29240317/inflammations-of-the-mammary-gland
#1
Tuomo Meretoja, Hanna Ihalainen, Marjut Leidenius
Breast inflammation, i.e. mastitis is an entity with a variable etiology and severity, typically affecting women of fertile age. In most cases, anamnesis reveals the etiology of the disease, bacterial puerperal mastitis associated with breastfeeding being the most common. Periductal mastitis is a breast inflammation typically associated with smoking in women of 40 to 50 years of age, localized to the region of the areola. Granulomatous mastitis and other rare breast inflammations usually require specialized care...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29151337/coexistence-of-idiopathic-granulomatous-mastitis-and-erythemanodosum-successful-treatment-with-corticosteroids
#2
Murat Akın, Harun Karabacak, Güldal Esendağlı, Aydın Yavuz, Serap Gültekin, Kürşat Dikmen, Hasan Bostancı
Background/aim: Idiopathic granulomatous mastitis (IGM) is a rare, chronic inflammatory disease of the breast. Erythema nodosum (EN) is a rare extramammary manifestation of IGM. The purpose of this study is to determine the clinical and demographic characteristics of 11 IGM and EN patients and to evaluate the efficacy of methylprednisolone treatment. Materials and methods: In our series, ten patients had EN bilaterally, whereas one patient had a lesion of the right pretibial area. The mean age of the patients was 35...
November 13, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29138800/broadleaf-mahonia-attenuates-granulomatous-lobular-mastitis%C3%A2-associated-inflammation-by-inhibiting-ccl%C3%A2-5-expression-in-macrophages
#3
Zhiyu Wang, Neng Wang, Xiaoyan Liu, Qi Wang, Biao Xu, Pengxi Liu, Huayu Zhu, Jianping Chen, Honglin Situ, Yi Lin
Granulomatous lobular mastitis (GLM) is a type of chronic mammary inflammation with unclear etiology. Currently systematic corticosteroids and methitrexate are considered as the main drugs for GLM treatment, but a high toxicity and risk of recurrence greatly limit their application. It is therefore an urgent requirement that safe and efficient natural drugs are found to improve the GLM prognosis. Broadleaf Mahonia (BM) is a traditional Chinese herb that is believed to have anti‑inflammatory properties according to ancient records of traditional Chinese medicine...
November 9, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29081405/the-enigma-of-granulomatous-mastitis-a-series
#4
Muhammad Umair Bashir, Alexius Ramcharan, Sarah Alothman, Sabine Beaugris Pa-C, Sarosh Ahmad Khan, Mohammed A Sbeih, Ryan Engdahl
Granulomatous mastitis is a chronic inflammatory breast disease with an enigmatic clinical presentation that can delay diagnosis and perpetuate ineffective treatments. We report our experience with the diagnosis and management of eighteen cases of granulomatous mastitis in the setting of an urban public hospital. The patients were identified after a retrospective review of pathology and surgery databases. Demographic, clinical, radiographic, histopathological data and treatment responses were reviewed. Out of a total of 18 patients, 8 patients were noted to be from Mexico...
February 20, 2017: Breast Disease
https://www.readbyqxmd.com/read/29038724/idiopathic-granulomatous-mastitis-dilemmas-in-diagnosis-and-treatment
#5
Rahim Mahmodlou, Niloofar Dadkhah, Fariba Abbasi, Jafar Nasiri, Rohollah Valizadeh
BACKGROUND: Idiopathic granulomatous mastitis (IGM) is a benign rare inflammatory disease of the breast. Due to its uncommon etiology, diagnosis and treatment is still unknown. Selection of a standard method for diagnosing idiopathic granulomatous mastitis is sophisticated. In view of non-definitive clinical and imaging finding, histopathology is the cornerstone of definitive diagnosis. OBJECTIVE: To determine and help solve the dilemma of treatment and diagnosis of idiopathic granulomatous mastitis...
September 2017: Electronic Physician
https://www.readbyqxmd.com/read/28956122/diffusion-weighted-imaging-in-relation-to-morphology-on-dynamic-contrast-enhancement-mri-the-diagnostic-value-of-characterizing-non-puerperal-mastitis
#6
Lina Zhang, Jiani Hu, Nicholas Guys, Jinli Meng, Jianguo Chu, Weisheng Zhang, Ailian Liu, Shaowu Wang, Qingwei Song
OBJECTIVES: To demonstrate the value of diffusion-weighted imaging (DWI) in the characterisation of mastitis lesions. METHODS: Sixty-one non-puerperal patients with pathologically confirmed single benign mastitis lesions underwent preoperative examinations with conventional MRI and axial DWI. Patients were categorised into three groups: (1) periductal mastitis (PDM), (2) granulomatous lobular mastitis (GLM), and (3) infectious abscess (IAB). Apparent diffusion coefficient (ADC) values of each lesion were recorded...
September 27, 2017: European Radiology
https://www.readbyqxmd.com/read/28931582/steroids-administered-after-vacuum-assisted-biopsy-in-the-management-of-idiopathic-granulomatous-mastitis
#7
J Q Deng, L Yu, Y Yang, X J Feng, J Sun, J Liu, F S Fan, L Q Liao
AIMS: The aetiology and treatment options for idiopathic granulomatous mastitis (IGM) are controversial. The aim was to study the clinical and diagnostic features and discuss medical and surgical treatment for IGM in our patients. METHODS: Sixty-five patients who met the histological criteria for IGM were retrospectively studied. The diagnosis of IGM was confirmed using Mammotome (an ultrasound-guided, vacuum-assisted biopsy system), core needle biopsy, quadrantectomy or segmental resection...
October 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28856149/is-idiopathic-granulomatous-mastitis-a-surgical-disease-the-jury-is-still-out
#8
Demetrios Moris, Christos Damaskos, Spyridon Davakis, Michail Vailas, Nikolaos Garmpis, Eleftherios Spartalis, Michael Kontos, Konstantinos Kontzoglou
Idiopathic granulomatous mastitis (IGM), is a rare entity of chronic inflammatory disorder of the breast of unknown etiology. Very few cases have been described so far, almost exclusively in women. Here we describe a case of IGM in a 53-year-old man presented with a right breast mass, progressively enlarging during the last 6 months. Due to the findings of clinical examination and CT-scan, the suspicion for a potentially malignant lesion was given and the decision for surgical resection was made. Microscopic analysis of the specimen showed non-caseating granulomas around mammary lobules, findings compatible with IGM...
August 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28845595/idiopathic-granulomatous-mastitis-associated-with-hyperprolactinemia-a-nonoperative-approach
#9
John Li, Hugh P McGregor
There is increasing evidence associating idiopathic granulomatous mastitis (IGM) with hyperprolactinemia. All documented cases have involved the patient having at least one operative procedure before the association has been made. We present a 55 year old female with IGM associated with risperidone induced hyperprolactinemia. She was successfully treated with a dopamine agonist, bromocriptine. We demonstrated that complete resolution can be achieved without surgical intervention, by targeting serum prolactin levels...
November 2017: Breast Journal
https://www.readbyqxmd.com/read/28764247/idiopathic-granulomatous-mastitis-a-clinical-puzzle-in-breast-lump-cases
#10
Vivek G Nath, Rakesh Sahoo, Avinash Sahoo, Jithendra Kumar Barad, K A Arun
Idiopathic granulomatous mastitis (IGM) is a rare benign disease, characterized by chronic inflammation and granulomatous disease process. A middle aged lady with breast lump for six months with equivocal mammographic and ultrasound results underwent lumpectomy and biopsy. Ruling out all other possible granulomatous diseases and malignancy, a diagnosis of IGM was made. IGM becomes clinically significant as it closely mimics carcinoma breast and some inflammatory and infectious pathology.
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28749097/lymphoepithelioma-like-carcinoma-of-the-breast-mimicking-granulomatous-mastitis-case-report-and-review-of-the-literature
#11
Dalia M Abouelfad, Noha N Yassen, Hebat Allah A Amin, Marwa E Shabana
Lymphoepithelioma-like carcinoma (LELC) of the breast is an exceedingly rare variant of mammary cancer. To our knowledge, only twenty - one cases have been reported in the literature. Diagnosis of this type of mammary carcinoma may be challenging, owing to its rarity and the histopathological similarity to common inflammatory and malignant lesions of the breast mainly granulomatous mastitis, medullary carcinoma, pleomorphic lobular carcinoma, lymphoma and other hematological malignancies. Our case is the 22nd case of lymphoepithelioma-like carcinoma reported in the breast, presenting with a palpable tender mass in a post-menopausal female...
July 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28749045/factors-related-to-recurrence-of-idiopathic-granulomatous-mastitis-what-do-we-learn-from-a-multicentre-study
#12
Erdal Uysal, Atilla Soran, Efe Sezgin
BACKGROUND: Idiopathic granulomatous mastitis (IGM) is a rare chronic inflammatory disease of the breast with unknown aetiology. Its treatment is controversial and the recurrence rate is high. The objectives of this study were to examine the demographic, sociocultural and clinical characteristics observed among a large cohort of IGM patients from Turkey and to identify factors related to the recurrence of IGM. METHODS: The study was designed as a multicentre retrospective study including 22 breast centres in Turkey...
July 27, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28740962/the-effect-of-corticosteroid-treatment-on-bilateral-idiopathic-granulomatous-mastitis
#13
Fatih Çiftci, İbrahim Abdurrahman, Zeynep Tatar
Idiopathic granulomatous mastitis (IGM) is the commonly encountered form of granulomatous mastitis that may result into repetitive infections and/or abscess formation. Mastitis may develop secondary to a systemic disorder such as tuberculosis, diabetes mellitus, or rheumatoid arthritis, or it may develop as an idiopathic disorder. Idiopathic granulomatous mastitis is the most frequent form of all granulomatous diseases affecting the breast. This disorder frequently presents as painful and fast-growing mass in the breast...
2017: Turkish Journal of Surgery
https://www.readbyqxmd.com/read/28740959/idiopathic-granulomatous-mastitis-an-institutional-experience
#14
Seetharam Prasad, Padmapriya Jaiprakash, Aniket Dave, Deepti Pai
OBJECTIVE: To study idiopathic granulomatous mastitis with respect to its various clinical features, etiologic factors, treatment modalities and complications. MATERIAL AND METHODS: Retrospective study of all patients who were diagnosed with idiopathic granulomatous mastitis from 1(st) January 2006 to 31(st) December 2014 at Kasturba Hospital, Manipal, India (a tertiary care referral centre). The research was performed according to the World Medical Association Declaration of Helsinki...
2017: Turkish Journal of Surgery
https://www.readbyqxmd.com/read/28739122/idiopathic-granulomatous-mastitis-a-diagnostic-and-therapeutic-challenge
#15
C M Freeman, B T Xia, G C Wilson, J D Lewis, S Khan, S J Lee, E E Lower, M J Edwards, E A Shaughnessy
BACKGROUND: Idiopathic granulomatous mastitis is a rare benign breast disease of women of reproductive age. It usually presents as a painful mass. Since the etiology is unclear, directed diagnosis and management is lacking. METHODS: This is a retrospective chart review of 14 patients, over twelve years (2004-2016), identified through query of pathology findings. RESULTS: Two asymptomatic patients were diagnosed after oncologic breast resection following neoadjuvant chemotherapy...
October 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28738795/is-surgical-excision-necessary-for-the-treatment-of-granulomatous-lobular-mastitis
#16
Young Duck Shin, Sung Su Park, Young Jin Song, Seung-Myoung Son, Young Jin Choi
BACKGROUND: We aimed to investigate the role of surgical excision in treating granulomatous lobular mastitis. METHODS: We performed a retrospective chart review of patients with granulomatous lobular mastitis treated from March 2008 to March 2014. We analyzed clinical features and therapeutic modalities and compared the patient outcomes based on treatment. RESULTS: During the study period, a total of 34 patients were diagnosed with granulomatous lobular mastitis and treated...
July 24, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28733047/idiopathic-granulomatous-mastitis-a-rare-benign-entitiy-that-can-simulate-breast-cancer
#17
Caridad Marín Hernández, Antonio Piñero Madrona, Pedro José Gil Vázquez, Pedro José Galindo Fernández, Pascual Parrilla Paricio
No abstract text is available yet for this article.
July 18, 2017: Cirugía Española
https://www.readbyqxmd.com/read/28731822/treatments-for-idiopathic-granulomatous-mastitis-systematic-review-and-meta-analysis
#18
Xin Lei, Kai Chen, Liling Zhu, Erwei Song, Fengxi Su, Shunrong Li
OBJECTIVES: Idiopathic granulomatous mastitis (IGM) is a benign breast disease with no ideal treatment regimen so far. This study aimed to evaluate the complete remission/resolution (CR) rate and recurrence rate of different treatment options. METHODS: We systematically searched and identified eligible studies from January 1, 2010, to December 31, 2015, in PubMed, EMBASE, Cochrane Central Register of Controlled Trials, and Medline databases. We included original studies reporting the CR and/or recurrence rate of each treatment used...
September 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28729183/differentiation-between-idiopathic-granulomatous-mastitis-and-malignant-breast-lesions-using-strain-ratio-on-ultrasonic-elastography
#19
B Yağcı, I Erdem Toslak, B Çekiç, M Öz, B R Karakaş, M Akdemir, S Yıldız, D Süren, D Bova
PURPOSE: The goal of this study was to investigate the strain elastography imaging characteristics of idiopathic granulomatous mastitis (IGM) and compare strain ratio values of IGM with those of breast cancer. MATERIAL AND METHODS: Twenty-three consecutive women with IGM (mean age, 37.9±6.6 [SD] years; range: 26-52 years) and 45 women with malignant breast tumor (mean age, 52.8±12.0 [SD], range, 32-77 years) who had been scheduled for ultrasound-guided core biopsy were recruited to the study...
October 2017: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/28655119/follow-up-of-granulomatous-mastitis-with-monitoring-versus-surgery
#20
Hasan Çalış, Serif Melih Karabeyoglu
BACKGROUND: IGM (Idiopathic Granulomatous Mastitis) is a rare, chronic, non-malignant and non-life-threatening breast disease. Clinically and radiologically, it has similar characteristics with other granulomatous diseases and breast carcinomas. METHODS: The patients whom diagnosed IGM according to pathology report were retrospectively evaluated between November 2014 and January 2016. The demographic properties, complaints during admission, diagnosis and treatment methods and clinical results were obtained via investigation of the patient files...
June 23, 2017: Breast Disease
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