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granulomatous mastitis

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https://www.readbyqxmd.com/read/29593062/novel-selective-medium-for-the-isolation-of-corynebacterium-kroppenstedtii-from-heavily-colonised-clinical-specimens
#1
Sally Cheuk Ying Wong, Rosana W S Poon, Chuen-Hing Foo, Antonio H Y Ngan, Herman Tse, Vivian C M Lam, Tiffany H Y Leung, Chun-Pong Wong, Vincent C C Cheng, Jonathan H K Chen, Kwok-Yung Yuen
AIMS: Granulomatous mastitis due to Corynebacterium kroppenstedtii is an increasingly recognised cause of an indolent and distressing mastitis in non-lactating females. This slow-growing lipophilic organism is not reliably isolated using routine culture methods. A novel selective culture medium (CKSM) is designed to optimise the isolation of this organism from clinical specimens. METHODS: CKSM contains 10% galactose and Tween 80 (10%) to enhance the growth of C...
March 28, 2018: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29575844/-multi-variated-analysis-of-differential-diagnosis-in-ultrasonography-of-idiopathic-granulomatous-mastitis-and-invasive-ductal-carcinoma
#2
C Yao, L L Chen, Y P Li, C Z Peng, M K Li, J Yao
Objective: To evaluate the differential diagnosis of idiopathic granulomatous mastitis (IGM) and invasive ductal carcinoma. Methods: The ultrasonographic data of 37 IGM patients and 50 cases of IDC were analyzed retrospectively. The shape, growth direction, margin, internal echo, posterior echo, calcification, Adler blood flow classification, PSV(peak sestolic velocity), RI (resistance index)and elasticity scores were analyzed by χ (2) test and independent sample t test. The optimal cutoff values of age, PSV and RI were calculated by receiver operating characteristic (ROC) curve...
March 23, 2018: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/29528819/idiopathic-granulomatous-mastitis-manifestations-at-multimodality-imaging-and-pitfalls
#3
Cedric W Pluguez-Turull, Jennifer E Nanyes, Cristina J Quintero, Hamza Alizai, Daniel D Mais, Kenneth A Kist, Nella C Dornbluth
Idiopathic granulomatous mastitis (IGM) is a rare benign inflammatory breast entity characterized by lobulocentric granulomas. IGM has a persistent or recurrent disease course and affects parous premenopausal women with a history of lactation. It has also been associated with hyperprolactinemia. The most common clinical sign is a palpable tender mass. However, the nonspecific manifestations and varied demographic features of this condition, as well as the other similar-appearing and superimposed breast entities, pose substantial diagnostic challenges...
March 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29514120/tuberculosis-mastitis-presenting-as-bilateral-breast-masses
#4
Yujie Qiao, Jessica H Hayward, Ronald Balassanian, Kimberly M Ray, Bonnie N Joe, Amie Y Lee
Tuberculosis mastitis can be a challenging diagnosis, often presenting with clinical and imaging findings that are suspicious for malignancy. We present a case of a 49-year-old female with a breast mass initially diagnosed as idiopathic granulomatous mastitis. Failure to respond to standard treatments, development of new breast masses, and discovery of a concurrent ulcerating thigh rash with similar histologic findings as the breast masses prompted further investigation, which ultimately lead to the diagnosis of tuberculosis mastitis...
February 23, 2018: Clinical Imaging
https://www.readbyqxmd.com/read/29479939/advantages-of-b-mode-ultrasound-combined-with-strain-elastography-in-differentiation-of-idiopathic-granulomatous-mastitis-from-malignant-breast-lesions
#5
Serdar Arslan, Fatih Öncü, Mehmet Ali Eryılmaz, Mehmet Sedat Durmaz, Ayşegül Altunkeser, Yaşar Ünlü
Background/aim: To evaluate the diagnostic performance of strain elastography (SE) combined with B-mode ultrasound in distinguishing between idiopathic granulomatous mastitis (IGM) and malignant breast lesions. Materials and methods: Seventy-seven malignant breast lesions and 36 IGM were assessed using B-mode ultrasound and SE. Ultrasonographic findings for all the breast lesions were classified based on the 2013 American College of Radiology Breast Imaging Reporting and Data System (BI-RADS-US), and the SE findings were evaluated based on the strain ratio and a five-point scale...
February 23, 2018: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29469699/mycophenolate-mofetil-as-a-successful-therapy-for-idiopathic-granulomatous-mastitis
#6
Fan Di Xia, Amy Ly, Gideon P Smith
Idiopathic granulomatous mastitis (IGM) is a benign chronic inflammatory breast disease of unknown etiology. No consensus exists as to the best therapeutic approach, though treatment choices include antibiotics, drainage, surgical excision, steroids, methotrexate, and observation. Herein we report a case of idiopathic granulomatous mastitis that was refractory to methotrexate and intralesional and systemic steroids but responded well to mycophenolate mofetil 1500mg twice daily. To our knowledge, this is the first report of the effective use of mycophenolate mofetil in idiopathic granulomatous mastitis...
July 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/29404980/granulomatous-diseases-of-the-breast-and-axilla-radiological-findings-with-pathological-correlation
#7
REVIEW
Jeffery E Illman, Simone B Terra, Allison J Clapp, Katie N Hunt, Robert T Fazzio, Sejal S Shah, Katrina N Glazebrook
OBJECTIVES: This article reviews our experience and describes the literature findings of granulomatous diseases of the breast and axilla. METHODS: After approval of the Institutional Review Board was obtained, the surgical pathological records from January 2000 to January 2017 were searched for the keyword granulomatous. Clinical, imaging and histology findings were reviewed by both a fellowship-trained radiologist and a breast-imaging consultant radiologist, reviewing 127 patients (age range, 32-86 years; 126 women and 1 man)...
February 5, 2018: Insights Into Imaging
https://www.readbyqxmd.com/read/29381437/diagnosis-and-treatment-of-75-patients-with-idiopathic-lobular-granulomatous-mastitis
#8
Jieqing Li
Idiopathic granulomatous lobular matitis (IGLM) is a rare non-specific inflammatory disease of the breast. Although IGLM is completely benign, it is easily confused with cancer due to progressive breast lump with firmly unilateral and discrete mass, nipple retraction and sinus formation. Patients with IGLM are usually associated with inflammation of the overlying skin. This study aimed to investigate the clinical characteristics of IGLM, treatment options and prognosis. From January 2010 to February 2015, 75 IGLM patients in our hospital were included, with an average age of 35...
January 30, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29350290/the-microbiology-and-treatment-of-human-mastitis
#9
REVIEW
Angeliki Angelopoulou, Des Field, C Anthony Ryan, Catherine Stanton, Colin Hill, R Paul Ross
Mastitis, which is generally described as an inflammation of breast tissue, is a common and debilitating disease which frequently results in the cessation of exclusive breastfeeding and affects up to 33% of lactating women. The condition is a primary cause of decreased milk production and results in organoleptic and nutritional alterations in milk quality. Recent studies employing culture-independent techniques, including metagenomic sequencing, have revealed a loss of bacterial diversity in the microbiome of mastitic milk samples compared to healthy milk samples...
April 2018: Medical Microbiology and Immunology
https://www.readbyqxmd.com/read/29322122/granulomatous-mastitis-concurrence-with-breast-cancer
#10
Hasan Çalış, Asuman Kilitçi
Idiopathic Granulomatous Mastitis (IGM) is a rare, chronic, non-malignant and non-life-threatening breast disease. IGM may mimic carcinoma of the breast. This case report is about concurrence of chronic granulomatous mastitis with breast cancer. The important aspect of this case is that it is the 4th case where IGM and breast cancer are present concurrently.
January 2018: European Journal of Breast Health
https://www.readbyqxmd.com/read/29322116/efficiency-of-imaging-modalities-in-male-breast-disease-can-ultrasound-give-additional-information-for-assessment-of-gynecomastia-evolution
#11
Özgür Sarıca, A Nedim Kahraman, Enis Öztürk, Memik Teke
Objective: The purpose of this study is to present mammography and ultrasound findings of male breast lesions and to investigate the ability of diagnostic modalities in estimating the evolution of gynecomastia. Materials and Methods: Sixty-nine male patients who admitted to Taksim and Bakirkoy Education and Research Hospitals and underwent mammography (MG) and ultrasonography (US) imaging were retrospectively evaluated. Duration of symptoms and mammographic types of gynecomastia according to Appelbaum's classifications were evaluated, besides the sonographic findings in mammographic types of gynecomastia...
January 2018: European Journal of Breast Health
https://www.readbyqxmd.com/read/29298955/infectious-and-inflammatory-breast-disease
#12
Kathryn Faguy
Breast inflammation can signal an array of breast conditions, from difficulties with breastfeeding to a rare and aggressive type of breast cancer. In some cases, these diseases resemble each other clinically and on imaging examinations. This article explains the inflammatory process and discusses a variety of localized benign inflammatory breast diseases, including lactational and nonlactational mastitis, ductal ectasia, idiopathic granulomatous mastitis, fat necrosis, and diabetic mastopathy. Inflammatory breast cancer also is presented, with an emphasis on its signs and symptoms, diagnosis, staging, multimodality treatment, and prognosis...
January 2018: Radiologic Technology
https://www.readbyqxmd.com/read/29240317/inflammations-of-the-mammary-gland
#13
REVIEW
Tuomo Meretoja, Hanna Ihalainen, Marjut Leidenius
Breast inflammation, i.e. mastitis is an entity with a variable etiology and severity, typically affecting women of fertile age. In most cases, anamnesis reveals the etiology of the disease, bacterial puerperal mastitis associated with breastfeeding being the most common. Periductal mastitis is a breast inflammation typically associated with smoking in women of 40 to 50 years of age, localized to the region of the areola. Granulomatous mastitis and other rare breast inflammations usually require specialized care...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29151337/coexistence-of-idiopathic-granulomatous-mastitis-and-erythemanodosum-successful-treatment-with-corticosteroids
#14
Murat Akın, Harun Karabacak, Güldal Esendağlı, Aydın Yavuz, Serap Gültekin, Kürşat Dikmen, Hasan Bostancı
Background/aim: Idiopathic granulomatous mastitis (IGM) is a rare, chronic inflammatory disease of the breast. Erythema nodosum (EN) is a rare extramammary manifestation of IGM. The purpose of this study is to determine the clinical and demographic characteristics of 11 IGM and EN patients and to evaluate the efficacy of methylprednisolone treatment. Materials and methods: In our series, ten patients had EN bilaterally, whereas one patient had a lesion of the right pretibial area. The mean age of the patients was 35...
November 13, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29138800/broadleaf-mahonia-attenuates-granulomatous-lobular-mastitis%C3%A2-associated-inflammation-by-inhibiting-ccl%C3%A2-5-expression-in-macrophages
#15
Zhiyu Wang, Neng Wang, Xiaoyan Liu, Qi Wang, Biao Xu, Pengxi Liu, Huayu Zhu, Jianping Chen, Honglin Situ, Yi Lin
Granulomatous lobular mastitis (GLM) is a type of chronic mammary inflammation with unclear etiology. Currently systematic corticosteroids and methitrexate are considered as the main drugs for GLM treatment, but a high toxicity and risk of recurrence greatly limit their application. It is therefore an urgent requirement that safe and efficient natural drugs are found to improve the GLM prognosis. Broadleaf Mahonia (BM) is a traditional Chinese herb that is believed to have anti‑inflammatory properties according to ancient records of traditional Chinese medicine...
January 2018: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29081405/the-enigma-of-granulomatous-mastitis-a-series
#16
Muhammad Umair Bashir, Alexius Ramcharan, Sarah Alothman, Sabine Beaugris, Sarosh Ahmad Khan, Mohammed A Sbeih, Ryan Engdahl
Granulomatous mastitis is a chronic inflammatory breast disease with an enigmatic clinical presentation that can delay diagnosis and perpetuate ineffective treatments. We report our experience with the diagnosis and management of eighteen cases of granulomatous mastitis in the setting of an urban public hospital. The patients were identified after a retrospective review of pathology and surgery databases. Demographic, clinical, radiographic, histopathological data and treatment responses were reviewed. Out of a total of 18 patients, 8 patients were noted to be from Mexico...
2017: Breast Disease
https://www.readbyqxmd.com/read/29038724/idiopathic-granulomatous-mastitis-dilemmas-in-diagnosis-and-treatment
#17
Rahim Mahmodlou, Niloofar Dadkhah, Fariba Abbasi, Jafar Nasiri, Rohollah Valizadeh
BACKGROUND: Idiopathic granulomatous mastitis (IGM) is a benign rare inflammatory disease of the breast. Due to its uncommon etiology, diagnosis and treatment is still unknown. Selection of a standard method for diagnosing idiopathic granulomatous mastitis is sophisticated. In view of non-definitive clinical and imaging finding, histopathology is the cornerstone of definitive diagnosis. OBJECTIVE: To determine and help solve the dilemma of treatment and diagnosis of idiopathic granulomatous mastitis...
September 2017: Electronic Physician
https://www.readbyqxmd.com/read/28956122/diffusion-weighted-imaging-in-relation-to-morphology-on-dynamic-contrast-enhancement-mri-the-diagnostic-value-of-characterizing-non-puerperal-mastitis
#18
Lina Zhang, Jiani Hu, Nicholas Guys, Jinli Meng, Jianguo Chu, Weisheng Zhang, Ailian Liu, Shaowu Wang, Qingwei Song
OBJECTIVES: To demonstrate the value of diffusion-weighted imaging (DWI) in the characterisation of mastitis lesions. METHODS: Sixty-one non-puerperal patients with pathologically confirmed single benign mastitis lesions underwent preoperative examinations with conventional MRI and axial DWI. Patients were categorised into three groups: (1) periductal mastitis (PDM), (2) granulomatous lobular mastitis (GLM), and (3) infectious abscess (IAB). Apparent diffusion coefficient (ADC) values of each lesion were recorded...
September 27, 2017: European Radiology
https://www.readbyqxmd.com/read/28931582/steroids-administered-after-vacuum-assisted-biopsy-in-the-management-of-idiopathic-granulomatous-mastitis
#19
J Q Deng, L Yu, Y Yang, X J Feng, J Sun, J Liu, F S Fan, L Q Liao
AIMS: The aetiology and treatment options for idiopathic granulomatous mastitis (IGM) are controversial. The aim was to study the clinical and diagnostic features and discuss medical and surgical treatment for IGM in our patients. METHODS: Sixty-five patients who met the histological criteria for IGM were retrospectively studied. The diagnosis of IGM was confirmed using Mammotome (an ultrasound-guided, vacuum-assisted biopsy system), core needle biopsy, quadrantectomy or segmental resection...
October 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28856149/is-idiopathic-granulomatous-mastitis-a-surgical-disease-the-jury-is-still-out
#20
Demetrios Moris, Christos Damaskos, Spyridon Davakis, Michail Vailas, Nikolaos Garmpis, Eleftherios Spartalis, Michael Kontos, Konstantinos Kontzoglou
Idiopathic granulomatous mastitis (IGM), is a rare entity of chronic inflammatory disorder of the breast of unknown etiology. Very few cases have been described so far, almost exclusively in women. Here we describe a case of IGM in a 53-year-old man presented with a right breast mass, progressively enlarging during the last 6 months. Due to the findings of clinical examination and CT-scan, the suspicion for a potentially malignant lesion was given and the decision for surgical resection was made. Microscopic analysis of the specimen showed non-caseating granulomas around mammary lobules, findings compatible with IGM...
August 2017: Annals of Translational Medicine
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