Nina Heppner, Sandra Reitmeier, Marjolein Heddes, Michael Vig Merino, Leon Schwartz, Alexander Dietrich, Markus List, Michael Gigl, Chen Meng, Daan R van der Veen, Melanie Schirmer, Karin Kleigrewe, Hélène Omer, Silke Kiessling, Dirk Haller
Microbiota assembly in the infant gut is influenced by diet. Breastfeeding and human breastmilk oligosaccharides promote the colonization of beneficial bifidobacteria. Infant formulas are supplemented with bifidobacteria or complex oligosaccharides, notably galacto-oligosaccharides (GOS), to mimic breast milk. To compare microbiota development across feeding modes, this randomized controlled intervention study (German Clinical Trial DRKS00012313) longitudinally sampled infant stool during the first year of life, revealing similar fecal bacterial communities between formula- and breast-fed infants (N = 210) but differences across age...
March 12, 2024: Cell Host & Microbe