keyword
https://read.qxmd.com/read/38533777/visceral-aorta-electrocautery-septotomy-to-allow-branched-endovascular-aortic-repair-in-ruptured-chronic-post-dissection-thoraco-abdominal-aneurysm
#1
JOURNAL ARTICLE
Martina Bastianon, Sara Di Gregorio, Caterina Melani, Jorge Miguel Mena Vera, Gaddiel Mozzetta, Fabio Grimaldi, Cristina Pallini, Giovanni Pratesi
PURPOSE: Endovascular repair of chronic post-dissection thoraco-abdominal aortic aneurysms (PD-TAAA) presents specific technical challenges due to the presence of chronic septum. Small true lumen diameter and false lumen visceral vessel origin can make branched endograft prohibitive. Septotomy may allow to overcome these challenges in cases of high complex anatomy. TECHNIQUE: We describe the application of electrocautery septotomy to the visceral aorta segment to deploy an off-the-shelf branched endograft in a chronic PD-TAAA rupture with true lumen collapse...
March 27, 2024: Journal of Endovascular Therapy
https://read.qxmd.com/read/38533578/aortic-events-and-relative-survival-in-patients-with-moderately-dilated-proximal-thoracic-aorta
#2
JOURNAL ARTICLE
Emelie Carlestål, Anders Franco-Cereceda, Christian Olsson
Objectives. This study describes growth, local and remote aortic events, and survival in patients with proximal (root, ascending) aortic diameters just below threshold for operation. Methods. Patients with proximal aortic diameter of 4.5 to 5.4 cm at baseline, were followed with serial computed tomography studies and data collected retrospectively. Aortic growth rate was estimated using mixed effects modelling. Clinical and radiological features associated with outcomes (all-cause death, aortic death, local or remote aortic events (dissection, rupture, intramural hematoma, or intervention)) were assessed with Cox analysis...
December 2024: Scandinavian Cardiovascular Journal: SCJ
https://read.qxmd.com/read/38533166/diagnostic-and-surgical-implications-of-non-occlusive-mesenteric-ischemic-ileus-associated-with-common-celiacomesenteric-trunk-a-case-report-and-literature-review
#3
Paul Joon Koo Choi, Jigyasha Pradhan, Sania Thite, Reshma Pydi, Gagan Sathya Prakash, Tiffany-Marie Golek, Sarah Moore, Ajay Shah, Hanasoge Girishkumar
The celiacomesenteric trunk (CMT), an exceedingly rare anatomic variant uniting the celiac artery and superior mesenteric artery (SMA), holds significant clinical and surgical implications. Despite its rarity, understanding these implications is crucial for effective management. This report outlines the case of a 99-year-old female presenting with septic shock and abdominal pain, with imaging revealing an incidental CMT. This paper aims to elucidate the surgical implications associated with CMT through a comprehensive case review and literature search...
February 2024: Curēus
https://read.qxmd.com/read/38532333/early-and-mid-term-outcomes-of-open-thoracoabdominal-aortic-aneurysm-repair-after-thoracic-endovascular-aortic-repair
#4
JOURNAL ARTICLE
Ji Lin, Wei Liu, Cheng-Wei Yang, Kaitao Jian, Yu Xia, Hao Peng, Bin You, Li-Zhong Sun
OBJECTIVE: To evaluate the early and mid-term outcomes of open repair in patients with thoracoabdominal aortic aneurysm (TAAA) after thoracic endovascular aortic repair (TEVAR). METHODS: This was a retrospective single center study. Data were retrospectively collected and analyzed for consecutive patients undergoing open TAAA repair (TAAAR) after TEVAR from November 2016 to June 2021. Indications for TAAAR included aneurysm progression due to endoleak, persisted false lumen perfusion, proximal/distal disease progression, and aorta rupture...
March 26, 2024: BMC Cardiovascular Disorders
https://read.qxmd.com/read/38531898/expanding-the-clinical-spectrum-of-biglycan-related-meester-loeys-syndrome
#5
JOURNAL ARTICLE
Josephina A N Meester, Anne Hebert, Maaike Bastiaansen, Laura Rabaut, Jarl Bastianen, Nele Boeckx, Kathryn Ashcroft, Paldeep S Atwal, Antoine Benichou, Clarisse Billon, Jan D Blankensteijn, Paul Brennan, Stephanie A Bucks, Ian M Campbell, Solène Conrad, Stephanie L Curtis, Majed Dasouki, Carolyn L Dent, James Eden, Himanshu Goel, Verity Hartill, Arjan C Houweling, Bertrand Isidor, Nicola Jackson, Pieter Koopman, Anita Korpioja, Minna Kraatari-Tiri, Liina Kuulavainen, Kelvin Lee, Karen J Low, Alan C Lu, Morgan L McManus, Stephen P Oakley, James Oliver, Nicole M Organ, Eline Overwater, Nicole Revencu, Alison H Trainer, Bhavya Trivedi, Claire L S Turner, Rebecca Whittington, Andreas Zankl, Dominica Zentner, Lut Van Laer, Aline Verstraeten, Bart L Loeys
Pathogenic loss-of-function variants in BGN, an X-linked gene encoding biglycan, are associated with Meester-Loeys syndrome (MRLS), a thoracic aortic aneurysm/dissection syndrome. Since the initial publication of five probands in 2017, we have considerably expanded our MRLS cohort to a total of 18 probands (16 males and 2 females). Segregation analyses identified 36 additional BGN variant-harboring family members (9 males and 27 females). The identified BGN variants were shown to lead to loss-of-function by cDNA and Western Blot analyses of skin fibroblasts or were strongly predicted to lead to loss-of-function based on the nature of the variant...
March 26, 2024: NPJ Genomic Medicine
https://read.qxmd.com/read/38528441/percutaneous-femoral-access-stuck-guide-wire-decannulation-difficulty-due-to-unravelling-and-knotting
#6
JOURNAL ARTICLE
Bhanu Pratap Singh Chauhan, Binita Dholakia, Ashfaque Khan, Chirag Hirani, Satheesh Kumar, Dibya Jyoti Mahakul, Abhishek Katyal, Wajid Nazir, Daljit Singh
Percutaneous techniques for femoral arterial access are increasingly being performed due to advances in endovascular cerebral procedures, as they provide a less morbid and minimally invasive approach than open procedures. Common complications associated with this peripheral puncture include hematoma, bleeding, pseudoaneurysm, arteriovenous fistula, retroperitoneal bleeding, inadvertent venous puncture, dissection, etc. The retrograde femoral access is currently the most frequently used arterial access as it is technically straightforward, allows for the use of larger size sheaths and catheters, allows repeated attempts, etc...
March 27, 2024: Journal of Cerebrovascular and Endovascular Neurosurgery
https://read.qxmd.com/read/38527007/right-sinus-of-valsalva-aneurysm-rupturing-into-the-right-atrium-and-dissecting-into-the-interventricular-septum
#7
Xing-Zhao Liu, Yong Huang, Zhi-Li Chen
The right sinus of the Valsalva aneurysm (SVA) rupturing into the right atrium (RA) and dissecting into the interventricular septum (IVS) is rare. The disease can be definitively diagnosed using two-dimensional (2D) echocardiography and color Doppler ultrasonography. Real-time biplane imaging and three-dimensional (3D) echocardiography offer new perspectives for viewing and diagnosing this disease.
March 2024: Echocardiography
https://read.qxmd.com/read/38519856/a-hybrid-approach-that-may-facilitate-the-repair-of-traumatic-popliteal-artery-pseudoaneurysms
#8
JOURNAL ARTICLE
Areti Vassiliou, Michail Peroulis, Vassilios Tatsis, Vangelis G Alexiou
PURPOSE: Traumatic popliteal pseudoaneurysms may occur in accidents or as an iatrogenic complication of a total knee arthroplasty. Complications often arise in open repair because of distorted anatomy. Up to 22% of the patients may suffer above-knee amputation. Endovascular treatment has proven to be an effective solution. However, the long-term performance of stents at the hinge point of the popliteal artery is questionable. We present a hybrid technique that was used successfully in 2 cases...
March 22, 2024: Journal of Endovascular Therapy
https://read.qxmd.com/read/38518600/emerging-regulatory-mechanisms-in-cardiovascular-disease-ferroptosis
#9
REVIEW
Sijie Jin, He Wang, Xiaohao Zhang, Mengyang Song, Bin Liu, Wei Sun
Ferroptosis, distinct from apoptosis, necrosis, autophagy, and other types of cell death, is a novel iron-dependent regulated cell death characterized by the accumulation of lipid peroxides and redox imbalance with distinct morphological, biochemical, and genetic features. Dysregulation of iron homeostasis, the disruption of antioxidative stress pathways and lipid peroxidation are crucial in ferroptosis. Ferroptosis is involved in the pathogenesis of several cardiovascular diseases, including atherosclerosis, cardiomyopathy, myocardial infarction, ischemia-reperfusion injury, abdominal aortic aneurysm, aortic dissection, and heart failure...
March 21, 2024: Biomedicine & Pharmacotherapy
https://read.qxmd.com/read/38516474/fluoroquinolones-neurological-complications-and-side-effects-in-clinical-practice
#10
REVIEW
Ahmed I Anwar, Lei Lu, Connor J Plaisance, Charles P Daniel, Chelsi J Flanagan, Danielle M Wenger, David McGregor, Giustino Varrassi, Adam M Kaye, Shahab Ahmadzadeh, Elyse M Cornett, Sahar Shekoohi, Alan D Kaye
Fluoroquinolones, a popular antibiotic class that inhibits nucleic acid synthesis of bacteria by disrupting the activity of the enzyme's topoisomerase IV and DNA gyrase, are used to treat bacterial infections. However, the widespread use of these drugs has allowed for the development of microbial resistance in recent years. Quinolones also have many clinically relevant side effects, including psychosis, confusion, seizures, headaches, dizziness, and nausea. Common side effects include tendinitis, myopathy, depression, and fatigue...
February 2024: Curēus
https://read.qxmd.com/read/38514127/-craniotomy-clipping-for-cerebral-aneurysms
#11
JOURNAL ARTICLE
Hiroki Uchida, Hidenori Endo
Preoperative simulation is essential to safely complete neurosurgical procedures. A vascular-oriented approach is important in cerebrovascular disorder surgery, considering anatomical variations among individuals. Particularly, subarachnoid hemorrhage surgery requires a detailed simulation of a safe dissection procedure, considering the rupture point of the aneurysm, and combined computed tomography or magnetic resonance imaging images with cerebral angiography can be useful. We present a case of subarachnoid hemorrhage and introduce the preoperative simulation performed at our hospital...
March 2024: No Shinkei Geka. Neurological Surgery
https://read.qxmd.com/read/38510088/a-direct-aorta-to-segmental-artery-bypass-for-prevention-of-spinal-cord-ischemia-after-endovascular-aortic-repair
#12
JOURNAL ARTICLE
Kevin T Kim, Ting I Wang, R Gregory Conway, Shahab Toursavadkohi, Jacob Cherian
Spinal cord ischemia remains a persistent challenge after endovascular aortic aneurysm repair. We present a novel direct aorta to segmental artery bypass before aneurysm repair in a 64-year-old woman presenting with an enlarging aneurysm following dissection. Through an eighth intercostal incision, a polyester graft was sewn into the aorta using pledgeted sutures. An entry needle was used to directly access the previously treated aortic segment, and the opening was stented and angioplasty was performed to create inflow...
June 2024: Journal of Vascular Surgery Cases and Innovative Techniques
https://read.qxmd.com/read/38509048/distal-extent-of-resection-in-type-a-dissection-keeping-it-simple
#13
JOURNAL ARTICLE
Marc R Moon, Puja Kachroo
No abstract text is available yet for this article.
March 21, 2024: Texas Heart Institute Journal
https://read.qxmd.com/read/38508323/cardiovascular-pathology-inheritance-and-prognosis-in-a-familial-cohort-of-loeys-dietz-type-iii
#14
JOURNAL ARTICLE
Robert T Kay, Pishoy Gouda, Robert C Welsh
INTRODUCTION: Loeys-Dietz syndrome (LDS) is a heritable disease that is the result of dysregulation of the transforming growth factor beta (TGFβ) pathway. The pathogenic variants associated with the condition are linked to aortic aneurysms and dissections along with other cardiovascular and non-cardiovascular abnormalities. LDS type III is associated with pathogenic variants in the SMAD3 gene responsible for signally in the TGFβ pathway. Most of the current knowledge of LDS stems from studies of LDS I and II patient with limited data on large cohorts of LDS III patients...
March 18, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38505712/%C3%AF-editors-choice%C3%AF-thoracic-endovascular-aortic-repair-and-spinal-cord-injury
#15
REVIEW
Hiroshi Banno, Changi Lee, Shuta Ikeda, Yohei Kawai, Masayuki Sugimoto, Kiyoaki Niimi
We previously reported that spinal cord injury following thoracic endovascular aortic repair for a thoracic aortic aneurysm is a micro embolism caused by a vulnerable mural thrombus. Conversely, patients who underwent thoracic endovascular aortic repair for aortic dissection develop spinal cord injury less frequently due to fewer mural thrombi. Paying attention to preserving blood flow toward the spinal cord, namely collateral circulation and steal phenomenon, prevents spinal cord injury following thoracic endovascular aortic repair for aortic dissection...
February 2024: Nagoya Journal of Medical Science
https://read.qxmd.com/read/38496659/extracardiac-manifestations-fail-to-predict-the-severity-of-cardiac-phenotype-in-children-and-young-adults-with-marfan-syndrome
#16
Sheba John, Luciana T Young, Ronald V Lacro, Arvind Hoskoppal, Zhining Ou, Angela Presson, Joyce T Johnson, Lauren Andrade, L LuAnn Minich, Shaji Menon
We performed a secondary analysis of the Pediatric Heart Network Marfan Trial public-use database to evaluate associations between extracardiac features and cardiac and aortic phenotypes in study participants. Aortic aneurysm phenotype was defined as aortic root Z-score ≥ 4.5, aortic root growth rate ≥ 75th percentile, aortic dissection, and aortic surgery. Severe cardiac phenotype was defined as aortic dissection, aortic Z-score ≥4.5, aortic valve surgery, at least moderate mitral regurgitation, mitral valve surgery, left ventricular dysfunction, or death...
March 4, 2024: Research Square
https://read.qxmd.com/read/38495218/cutting-balloon-septotomy-for-repair-of-right-common-iliac-artery-aneurysm-in-the-setting-of-type-b-aortic-dissection
#17
JOURNAL ARTICLE
Angel Hsu, Michael S Segal, Cindy Sturt, Bruce Brener
We report a case of using cutting balloon septotomy for a 5-cm right common iliac artery aneurysm repair in a patient with a chronic type B aortic dissection after open repair 10 years before. This technique uses intravenous ultrasound to facilitate deployment of a cutting balloon to shear through the dissection flap, allowing for optimization of the landing zone for endovascular repair of a right common iliac artery aneurysm. Various methods are available for performing septotomy, and the use of a cutting balloon is one that helps with stent placement and position...
June 2024: Journal of Vascular Surgery Cases and Innovative Techniques
https://read.qxmd.com/read/38487034/acute-dissection-of-a-syphilitic-saccular-aneurysm-of-the-ascending-aorta-and-arch-in-a-hypertensive-patient-a-rare-phenomenon
#18
Hubert Daisley, Dennecia George, Johann Daisley
We report the case of a 77-year-old male who suffered from hypertension and died suddenly. At autopsy, he was found to have hypertensive cardiomegaly and a dissecting syphilitic saccular aneurysm of the ascending aorta and arch with tamponade. Chronic aortic regurgitation, which is often seen in syphilitic aortitis, produces an additive effect to the concentric left ventricular hypertrophy seen in hypertension.
2024: Autopsy & Case Reports
https://read.qxmd.com/read/38486025/a-yeast-based-assay-establishes-the-pathogenicity-of-novel-missense-acta2-variants-associated-with-aortic-aneurysms
#19
JOURNAL ARTICLE
Cristina Calderan, Ugo Sorrentino, Luca Persano, Eva Trevisson, Geppo Sartori, Leonardo Salviati, Maria Andrea Desbats
The ACTA2 gene codes for alpha-smooth muscle actin, a critical component of the contractile apparatus of the vascular smooth muscle cells. Autosomal dominant variants in the ACTA2 gene have been associated to familial non-syndromic thoracic aortic aneurysm/dissection (TAAD). They are thought to act through a dominant-negative mechanism. These variants display incomplete penetrance and variable expressivity, complicating the validation of ACTA2 variants pathogenicity by family segregation studies. In this study, we developed a yeast based assay to test putative TAAD-associated ACTA2 variants...
March 15, 2024: European Journal of Human Genetics: EJHG
https://read.qxmd.com/read/38485809/successful-management-of-splenic-artery-dissection-after-sigmoid-colon-perforation-in-vascular-ehlers-danlos-syndrome
#20
JOURNAL ARTICLE
Moegi Yoshizaki, Yasuko Matsuo, Satoshi Yasuda, Shunsuke Doi, Takeshi Sakata, Minako Nagai, Kota Nakamura, Yuichiro Kohara, Shohei Toyoda, Toshihiro Tanaka, Masayuki Sho
BACKGROUND: Ehlers-Danlos syndrome (EDS) is a genetic disorder that causes fragility of the systemic connective tissues. Of the 13 subtypes, vascular EDS (vEDS) is associated with abnormalities in collagen production, resulting in arterial rupture and intestinal perforation. Herein, we report the case of a man with confirmed vEDS who survived a ruptured dissected splenic artery aneurysm triggered by perforation of the sigmoid colon. CASE PRESENTATION: A 48-year-old man presented to our hospital with sudden severe lower abdominal pain...
March 15, 2024: Surgical Case Reports
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