keyword
MENU ▼
Read by QxMD icon Read
search

Neonatal hyperbilirubinemia

keyword
https://www.readbyqxmd.com/read/27892440/urinary-tract-infection-in-asymptomatic-newborns-with-prolonged-unconjugated-hyperbilirubunemia-a-hospital-based-observational-study-from-western-region-of-nepal
#1
T Malla, B Sathian, K Karmacharya Malla, S Adhikari
Background Urine culture is usually not a part of work-up for neonatal unconjugated hyperbilirubinemia; hence its prevalence remains unknown. Objective This study was done to determine the incidence of urinary tract infection (UTI) in asymptomatic newborns with prolonged unconjugated hyperbilirubinemia and to evaluate which other laboratory parameters are associated with UTIs. Method A prospective observational study where jaundiced newborns otherwise clinically well, were evaluated for UTI. The study was carried out in neonatal intensive care unit of Manipal Teaching Hospital, Pokhara from June 2012 -April 2013...
January 2016: Kathmandu University Medical Journal (KUMJ)
https://www.readbyqxmd.com/read/27878783/prediction-of-significant-hyperbilirubinemia-in-term-neonates-by-early-non-invasive-bilirubin-measurement
#2
Manish Jain, Akash Bang, Anju Tiwari, Shuchi Jain
BACKGROUND: Neonatal jaundice is a common problem. We evaluated the utility and best cut-off values of 24-and 48-hour transcutaneous bilirubin indices (TcBI) in predicting subsequent significant hyperbilirubinemia and evaluated various associated maternal and fetal risk factors. METHODS: TcBI at 24 and 48 hours and serum bilirubin levels at 72 hours of age were obtained for healthy, term, appropriate for gestational age neonates. Neonates with prematurity, birth weight <2500 g, ABO or Rh incompatibility, onset of clinical jaundice <24 hours, clinical suspicion of septicemia, positive pressure ventilation at birth, admission in neonatal intensive care unit and contraindications for BiliChek were excluded...
November 23, 2016: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/27869251/an-increased-genotoxic-risk-in-lymphocytes-from-phototherapy-treated-hyperbilirubinemic-neonates
#3
Seyed Alireza Mesbah-Namin, Maryam Shahidi, Maryam Nakhshab
BACKGROUND: Phototherapy is believed to be a safe method for the management of hyperbilirubinemia. However, there are some controversial issues regarding the genotoxic effects of phototherapy on DNA. The aim of this study was to investigate morphologically both phototherapy-induced DNA double-strand breaks (DSBs) and apoptosis in lymphocytes derived from jaundiced and non-jaundiced neonates. METHODS: Newborns were divided into three groups, including phototherapy-treated (PT, n=30) jaundiced newborns with total serum bilirubin (TSB) levels >15 mg/dl, non-treated jaundiced newborns (C+, n=27), as positive, as well as healthy negative (C-, n=30) controls with TSB levels ranging from 10 and 15 mg/dl and less than 5 mg/dl, respectively...
November 21, 2016: Iranian Biomedical Journal
https://www.readbyqxmd.com/read/27863965/robustness-of-the-reichert-unistat-bilirubinometer-for-analysis-of-hemolyzed-samples-from-neonates
#4
Christopher R McCudden, Kathy Fleming, Michelle Warr
BACKGROUND AND OBJECTIVES: Bilirubin is routinely measured in neonates to avoid the irreversible effects of kernicterus. Grossly hemolyzed samples are routinely rejected under the assumption that bilirubin cannot be accurately measured in hemolyzed samples. The objective of this study was to determine the effect of hemolysis on bilirubin measurement in neonates. METHODS: Data included 2-years of paired bilirubin results (n=70) where hemolyzed and non-hemolyzed samples were collected and measured within 6h of each other...
November 15, 2016: Clinical Biochemistry
https://www.readbyqxmd.com/read/27842454/the-role-of-ugt1a1-promoter-polymorphism-and-exon-1-mutations-in-neonatal-jaundice
#5
Hülya Halis, Hacer Ergin, Aylin Köseler, Erol Ömer Atalay
OBJECTIVE: In the present study we investigated the effects of promoter polymorphism and an exon-1 mutation (G71R) in the UGT1A1 gene in neonates with unexplained hyperbilirubinemia and direct coombs-negative [DC(-)] ABO incompatibility. METHODS: Two hundred term neonates in their first week of life and without additional icterogenic factors were included in the study. Neonates with a serum total bilirubin (STB) level≥17 mg/dL constituted the hyperbilirubinemia group (n = 100) while the control group comprised healthy neonates with a STB level < 12...
November 14, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27806795/-infantile-cholestasis-caused-by-cftr-mutation-case-report-and-literature-review
#6
L Li, N L Wang, J Y Gong, J S Wang
Objective: To study the clinical presentation, biochemical features and genetic analysis of an infant with cholestasis related to the CFTR mutations. Method: The clinical presentation, laboratory investigations and management of a case with infantile cholestasis caused by CFTR mutations were summarized and the relevant literature was reviewed. Result: (1) The patient was a 5 months old boy with cholestasis which developed in neonatal period with delayed meconium exclusion.The laparoscopic exploration was performed to exclude biliary atresia because of acholic stool when he was two months old...
November 2, 2016: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/27799069/effects-of-ultrasound-pregnancy-dating-on-neonatal-morbidity-in-late-preterm-and-early-term-male-infants-a-register-based-cohort-study
#7
Merit Kullinger, Bengt Haglund, Helle Kieler, Alkistis Skalkidou
BACKGROUND: Assessing gestational age by ultrasound can introduce a systematic bias due to sex differences in early growth. METHODS: This cohort study included data on 1,314,602 births recorded in the Swedish Medical Birth Register. We compared rates of prematurity-related adverse outcomes in male infants born early term (gestational week 37-38) or late preterm (gestational week 35-36), in relation to female infants, between a time period when pregnancy dating was based on the last menstrual period (1973-1978), and a time period when ultrasound was used for pregnancy dating (1995-2010), in order to assess the method's influence on outcome by fetal sex...
October 31, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27790538/predictive-value-of-total-serum-bilirubin-within-6-hour-of-birth-for-the-development-of-hyperbilirubinemia-after-72-hours-of-birth
#8
Chaitra Bandi, Raghavendra Vanaki, Ashok V Badakali, Ramesh R Pol, Bhuvaneshwari Yelamali
INTRODUCTION: Neonatal jaundice is benign and no intervention might be required, but jaundice can be associated with an underlying disease condition, which therefore warrants accurate and unbiased estimation of bilirubin. Total Serum Bilirubin (TSB) measurements (at discharge between 18 hours and 72 hours) can be used to predict the chances of developing severe hyperbilirubinemia. MATERIALS AND METHODS: The present hospital-based prospective study was undertaken to determine the predictive value of serum bilirubin before 6 hours of life for subsequent hyperbilirubinemia in healthy term neonates...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27768017/green-teeth-caused-by-neonatal-hyperbilirubinemia
#9
José Uberos, Mariam Tribak, María P Tortosa Pinto, Aida Ruiz López
No abstract text is available yet for this article.
December 2016: Minerva Pediatrica
https://www.readbyqxmd.com/read/27763628/reliability-of-transcutaneous-bilirubinometry-from-shielded-skin-in-neonates-receiving-phototherapy-a-prospective-cohort-study
#10
L Murli, A Thukral, M J Sankar, S Vishnubhatla, A K Deorari, V K Paul, A Sakariah, Dolma, R Agarwal
OBJECTIVE: To determine the agreement between transcutaneous bilirubin (TcB) measured from shielded skin and serum total bilirubin (STB) in infants (34 to 41 weeks of gestation) with hyperbilirubinemia receiving phototherapy (PT). STUDY DESIGN: In this prospective cohort study, we shielded a small area of skin on sternum using a commercial photo-opaque patch (BilEclipseTM, Philips Respironics, Murrysville, PA, USA). The TcB from the shielded skin (TcBs) and STB were measured at four time points-before initiation, 12 and 24 h during and once after (12 h) cessation of PT...
October 20, 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/27749537/telbivudine-treatment-of-hepatitis-b-virus-infected-pregnant-women-at-different-gestational-stages-for-the-prevention-of-mother-to-child-transmission-outcomes-of-telbivudine-treatment-during-pregnancy
#11
Zhangmin Tan, Yuzhu Yin, Jin Zhou, Lingling Wu, Chengfang Xu, Hongying Hou
This prospective study evaluated the viability of telbivudine for blocking mother-to-child transmission (MTCT) of hepatitis B virus (HBV) infection.Pregnant women positive for the hepatitis B surface antigen began telbivudine treatment before 14 weeks of gestation (i.e., early), between 14 and 28 weeks of gestation (late), or not at all (control). In the late-treatment group, 55 women terminated telbivudine therapy within puerperium. All neonates underwent routine hepatitis B immunoglobulin plus vaccination...
October 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27746740/moderate-hyperbilirubinemia-alters-neonatal-cardiorespiratory-control-and-induces-inflammation-in-the-nucleus-tractus-solitarius
#12
Marie-Laure Specq, Mélisande Bourgoin-Heck, Nathalie Samson, François Corbin, Christian Gestreau, Maxime Richer, Hazim Kadhim, Jean-Paul Praud
Hyperbilirubinemia (HB) occurs in 90% of preterm newborns. Moderate HB can induce acute neurological disorders while severe HB has been linked to a higher incidence of apneas of prematurity. The present study aimed to test the hypothesis that even moderate HB disrupts cardiorespiratory control in preterm lambs. Two groups of preterm lambs (born 14 days prior to term), namely control (n = 6) and HB (n = 5), were studied. At day 5 of life, moderate HB (150-250 μmol/L) was induced during 17 h in the HB group after which cardiorespiratory control as well as laryngeal and pulmonary chemoreflexes were assessed during baseline recordings and during hypoxia...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27746217/a-new-rat-model-of-neonatal-bilirubin-encephalopathy-kernicterus
#13
Naser Amini, Nasim Vousooghi, Mansoureh Soleimani, Ali Samadikuchaksaraei, Mehdi Akbari, Hosein Safakheil, Pezhman Atafimanesh, Ali Shahbazi, Peiman Brouki Milan, Sara Ramezani, Masoud Mozafari, Mohammad Taghi Joghataei
INTRODUCTION: Hemolytic kernicterus, an indirect bilirubin-induced brain dysfunction, is associated with hyper-bilirubinemia in mammalian neonates. In this study, a new model of kernicterus has been developed using intra-peritoneal injections of phenyl hydrazine and subcutaneous injections of sulfisoxazole. These drugs can potentially induce kernicterus in neonatal through changes in hemolysis and hypo-albumin. METHODS: For this purpose, 7-day-old male Wistar rats (n=72; mean weight 11±1g) were used...
October 13, 2016: Journal of Pharmacological and Toxicological Methods
https://www.readbyqxmd.com/read/27735930/prenatal-visit-utilization-and-outcomes-in-pregnant-women-with-type-ii-and-gestational-diabetes
#14
E B Carter, M G Tuuli, A O Odibo, G A Macones, A G Cahill
OBJECTIVE: To investigate the association between the number of prenatal visits (PNVs) and pregnancy outcomes in women with gestational diabetes (GDM) and Type 2 diabetes mellitus (DM). STUDY DESIGN: A 4-year prospective cohort study of women with GDM and DM and was conducted. Patients ⩾75th percentile for number of PNVs were compared with those ⩽25th percentile. The primary outcomes were large for gestational age (LGA) with birth weight >90% and neonatal intensive care unit (NICU) admission for >24 h...
October 13, 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/27718221/auditory-toxicity-in-late-preterm-and-term-neonates-with-severe-jaundice
#15
Sanjiv B Amin, Satish Saluja, Arvind Saili, Nirupama Laroia, Mark Orlando, Hongyue Wang, Asha Agarwal
AIM: Jaundice may cause auditory toxicity (auditory neuropathy and hearing loss). However, total serum bilirubin (TSB) does not discriminate neonates at risk for auditory toxicity. We compared TSB, bilirubin:albumin molar ratio (BAMR), and unbound bilirubin for their association with auditory toxicity in neonates with severe jaundice (TSB ≥342μmol/L, or that met exchange transfusion). METHOD: Neonates greater or equal to 34 weeks gestational age with severe jaundice during the first 2 postnatal weeks were eligible for prospective cohort study, unless they had craniofacial malformations, chromosomal disorders, toxoplasmosis, other infections, rubella, cytomegalovirus, herpes simplex infections, surgery, or family history of congenital deafness...
October 8, 2016: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/27718120/ceftriaxone-associated-biliary-and-cardiopulmonary-adverse-events-in-neonates-a-systematic-review-of-the-literature
#16
Patrick C Donnelly, Rebecca M Sutich, Ryan Easton, Oluwatunmise A Adejumo, Todd A Lee, Latania K Logan
BACKGROUND: Ceftriaxone is a third-generation cephalosporin with broad-spectrum activity against both Gram-positive and Gram-negative bacteria. Despite its effectiveness, its use for the treatment of infections in neonatal patients has been limited because of concern about its potential toxicity. OBJECTIVE: Our aim was to review the literature for an association between ceftriaxone and cardiopulmonary events, hyperbilirubinemia, and pseudolithiasis among neonates...
October 7, 2016: Paediatric Drugs
https://www.readbyqxmd.com/read/27704083/fiber-enhanced-raman-spectroscopic-analysis-as-a-novel-method-for-diagnosis-and-monitoring-of-diseases-related-to-hyperbilirubinemia-and-hyperbiliverdinemia
#17
Di Yan, Christian Domes, Robert Domes, Timea Frosch, Jürgen Popp, Mathias W Pletz, Torsten Frosch
Fiber enhanced resonance Raman spectroscopy (FERS) is introduced for chemically selective and ultrasensitive analysis of the biomolecules hematin, hemoglobin, biliverdin, and bilirubin. The abilities for analyzing whole intact, oxygenated erythrocytes are proven, demonstrating the potential for the diagnosis of red blood cell related diseases, such as different types of anemia and hemolytic disorders. The optical fiber enables an efficient light-guiding within a miniaturized sample volume of only a few micro-liters and provides a tremendously improved analytical sensitivity (LODs of 0...
October 17, 2016: Analyst
https://www.readbyqxmd.com/read/27669736/risk-of-autism-associated-with-hyperbilirubinemia-and-phototherapy
#18
Yvonne W Wu, Michael W Kuzniewicz, Lisa Croen, Eileen M Walsh, Charles E McCulloch, Thomas B Newman
OBJECTIVE: Whether neonatal hyperbilirubinemia and/or phototherapy increase the risk of autism spectrum disorder (ASD) is unclear. We sought to quantify the risk of ASD associated with elevated total serum bilirubin (TSB) levels and with phototherapy. METHODS: In a retrospective cohort study of 525 409 infants born at ≥35 weeks' gestation in 15 Kaiser Permanente Northern California (KPNC) hospitals, 1995-2011, we obtained all TSB levels and determined which infants received phototherapy...
September 26, 2016: Pediatrics
https://www.readbyqxmd.com/read/27633666/comparison-between-maternal-and-neonatal-serum-vitamin-d-levels-in-term-jaundiced-and-nonjaundiced-cases
#19
Seyyed Mohammad Hassan Aletayeb, Masoud Dehdashtiyan, Majid Aminzadeh, Arash Malekyan, Somayeh Jafrasteh
BACKGROUND: Neonatal jaundice is the result of an imbalance between the production and conjugation of bilirubin. Considering the multiple roles of vitamin D, lower levels of vitamin D in these cases may be associated with neonatal jaundice. The present study was undertaken for the purpose of comparing serum vitamin D levels in healthy term jaundiced and nonjaundiced newborns and their mothers. METHODS: This case-control study was conducted in 60 term newborns and their mothers from a teaching and referral children's hospital in the southwestern region of Iran, from December 22, 2013 through March 22, 2014...
September 12, 2016: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/27617068/evaluation-of-serum-zinc-levels-in-hyperbilirubinemic-neonates-before-and-after-phototherapy
#20
Ziba Mosayebi, Maral Rahmani, Shahin Behjati Ardakani, Mahdi Sheikh, Mamak Shariat, Golnaz Rezaeizadeh
BACKGROUND: The existing therapeutic methods for neonatal jaundice are costly, time-consuming and potentially risky. Zinc salts can reduce phototherapy duration by precipitating unconjugated bilirubin in the intestine (bilirubin and zinc can form a complex in physiologic pH); however, zinc toxicity is an issue that must be considered since theoretically bilirubin reduction by phototherapy may increase serum zinc levels, making additional zinc supplementation the potential cause of zinc toxicity...
June 2016: Iranian Journal of Pediatrics
keyword
keyword
103310
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"