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COMPARATIVE STUDY
R Braun, U Mangold, R Mangold
N-Methyl-N-beta-chloroethyl-hydrazine and its bezaldehydhydrazone inhibit the synthesis of DNA and RNA in ascites cells in vitro faster and stronger than N,N-Dimethylhydrazine and procarbazina does. The benzaldehydhydrzone essentially inhibits influx and phosphorylation of nucleosides whereas N-Methyl-N-beta-chloroethylhydrazine acts directly on DNA synthesis.
December 9, 1976: Zeitschrift Für Krebsforschung und Klinische Onkologie. Cancer Research and Clinical Oncology
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