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https://www.readbyqxmd.com/read/28919625/van-wyk-and-grumbach-syndrome-an-unusual-presentation-of-hypothyroism
#1
P K Chanda, M Kamrul-Hasan, M Abu-Bakar, M Rahman, M A Kader, M A Hossain, N I Siddiqui
An 18 years-old-girl presented one and half years back with the complaints of short stature, retarded growth, and menorrhagia with sudden severe lower abdominal pain; was diagnosed as bilateral ovarian cysts and underwent bilateral ovarian cystectomy. Later on she was incidentally diagnosed as a case of hypothyroidism when she had been experiencing slowly enlarging left lower abdominal mass with dull ache for the 5 month and then was transferred to the department of Endocrinology for further evaluation. Detailed work up revealed her short stature with obesity, delayed bone age and other features of hypothyroidism which was confirmed by thyroid function testing...
July 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28910309/pattern-and-severity-of-multimorbidity-among-patients-attending-primary-care-settings-in-odisha-india
#2
Sanghamitra Pati, Subhashisa Swain, Job Metsemakers, J André Knottnerus, Marjan van den Akker
Multimorbidity is increasingly the primary concern of healthcare systems globally with substantial implications for patient outcomes and resource cost. A critical knowledge gap exists as to the magnitude of multimorbidity in primary care practice in low and middle income countries with available information limited to prevalence. In India, primary care forms the bulk of the health care delivery being provided through both public (community health center) and private general practice setting. We undertook a study to identify multimorbidity patterns and relate these patterns to severity among primary care attendees in Odisha state of India...
2017: PloS One
https://www.readbyqxmd.com/read/28899700/the-agony-of-it-all-musculoskeletal-discomfort-in-the-reading-room
#3
Rebecca L Seidel, Elizabeth A Krupinski
PURPOSE: The purpose of this study was to determine the extent and severity of musculoskeletal discomfort in radiologists using a standardized tool, the Cornell Musculoskeletal Discomfort Questionnaire (CMDQ). In addition, we evaluated the influence of demographic factors on the frequency of symptoms, degree of discomfort, interference of symptoms with ability to work, and overall pain. METHODS: The CMDQ was distributed via an anonymous link to all radiology trainees and faculty at our institution...
September 9, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28845945/-laparoscopic-antevasal-uretero-ureteral-anastomosis-for-treating-retrocaval-ureter
#4
B K Komyakov, B G Guliev, Sh N Idrisov, R G Shibliev
The article presents a case of laparoscopic antevasal correction of the retrocaval ureter in a 16 year old patient, who was admitted to the hospital with complaints of aching pain in the right lower back. His history was noteworthy of early age onset of intermittent fever accompanied by abdominal and lumbar pain. Blood count and urinalysis were within normal limits, and he was treated symptomatically. However, no renal ultrasound scan was done. Intravenous urography and MSCT showed a retrocaval ureter. The diagnosis was confirmed by retrograde ureteropyelography...
July 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28841665/prevalence-and-pattern-of-co-morbidity-among-type2-diabetics-attending-urban-primary-healthcare-centers-at-bhubaneswar-india
#5
Sandipana Pati, F G Schellevis
OBJECTIVE: India has the second largest diabetic population in the world. The chronic nature of the disease and high prevalence of co-existing chronic medical conditions or "co morbidities" makes diabetes management complex for the patient and for health care providers. Hence a strong need was felt to explore the problem of co morbidity among diabetics and its dimensions in primary health care practices. METHOD: This cross sectional survey was carried out on 912 type 2 diabetes patients attending different urban primary health care facilities at Bhubaneswar...
2017: PloS One
https://www.readbyqxmd.com/read/28769073/compensatory-vasodilator-mechanisms-in-the-ophthalmic-artery-of-endothelial-nitric-oxide-synthase-gene-knockout-mice
#6
Caroline Manicam, Natalja Ginter, Huige Li, Ning Xia, Evgeny Goloborodko, Jenia Kouchek Zadeh, Aytan Musayeva, Norbert Pfeiffer, Adrian Gericke
Nitric oxide (NO) generated by endothelial nitric oxide synthase (eNOS) plays an important role in the maintenance of ocular vascular homeostasis. Therefore, perturbations in vascular NO synthesis have been implicated in the pathogenesis of several ocular diseases. We recently reported that eNOS contributes significantly to vasodilation of the mouse ophthalmic artery. Interestingly, dilatory responses were also retained in eNOS gene-deficient mice (eNOS-/-), indicating inherent endothelial adaptive mechanism(s) that act as back-up systems in chronic absence of eNOS to preserve vasorelaxation...
August 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28723110/portable-sensor-for-the-detection-of-choline-and-its-derivatives-based-on-silica-isoporous-membrane-and-gellified-nanointerfaces
#7
Lisiqi Xie, Xiao Huang, Bin Su
A portable amperometric ion sensor was fabricated by integrating silica isoporous membrane (SIM) and organogel composed of polyvinyl chloride and 1,2-dichloroethane (PVC-DCE) on a 3D-printed polymer chip. The detection of ionic species in aqueous samples could be accomplished by adding a microliter of sample droplet to the sensor and by identifying the ion-transfer potential and current magnitude at the water/organogel interface array templated by SIM. Thanks to the ultrasmall channel size (2-3 nm in diameter), high channel density (4 × 10(8) μm(-2)), and ultrathin thickness (80 nm) of SIM, the ensemble of nanoscopic water/organogel (nano-W/Gel) interface array behaved like a microinterface with two back-to-back hemispherical mass diffusion zones...
June 23, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28672421/-acute-coronary-syndrome-what-should-the-general-practitioner-do
#8
REVIEW
Stefan Stadler, Dierk Endemann, Lars S Maier
Acute myocardial infarction is the second most common cause of mortality in Germany after chronic ischemic cardiac disease. It is essential to think of acute coronary syndrome also in patients who do not present with typical signs (pressure, tightness, pain, or a squeezing or aching sensation in the chest or arms that may spread to the neck, jaw or back) in the general practitioner's practice. Vital signs (blood pressure, heart rate and oxygen saturation) must be measured; an ECG should be recorded and analyzed within ten minutes of first medical contact...
July 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28626756/a-pilot-study-on-bioactive-constituents-and-analgesic-effects-of-myrliq%C3%A2-a-commiphora-myrrha-extract-with-a-high-furanodiene-content
#9
Antonio Germano, Andrea Occhipinti, Francesca Barbero, Massimo E Maffei
The analgesic properties of myrrh (Commiphora myrrha) have been known since ancient times and depend on the presence of bioactive sesquiterpenes with furanodiene skeletons. MyrLiq is a C. myrrha extract with a standardized content of curzerene, furanoeudesma-1,3-diene, and lindestrene (12.31 ± 0.05 g kg(-1), 18.84 ± 0.02 g kg(-1), and 6.23 ± 0.01 g kg(-1), resp.) and a high total furanodiene content (40.86 ± 0.78 g kg(-1)). A balanced sample of 95 female and 89 male volunteers (with ages ranging from 18 to older than 60 years) exhibiting different pain pathologies, including headache, fever-dependent pain, joint pain, muscle aches, lower back pain, and menstrual cramps, was divided into two groups...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28503347/wasting-of-extensor-digitorum-brevis-as-a-decisive-preoperative-clinical-indicator-of-lumbar-canal-stenosis-a-single-center-prospective-cohort-study
#10
S Munakomi, B M Kumar
BACKGROUND: The dilemma in managing patients with low back ache lies in differentiating radiculopathy from lumbar canal stenosis. This has a huge bearing in patients being planned for surgical intervention as underperforming leads to failed back syndrome whereas over-doing leads to instability. There still remains a loophole in clinically diagnosing lumbar canal stenosis. AIM: We opt to utilize a simple bedside clinical examination in routinely assessing patients presenting with low back ache in ruling out underlying canal stenosis...
September 2016: Annals of Medical and Health Sciences Research
https://www.readbyqxmd.com/read/28435318/prevalence-characteristics-and-burden-of-failed-back-surgery-syndrome-the-influence-of-various-residual-symptoms-on-patient-satisfaction-and-quality-of-life-as-assessed-by-a-nationwide-internet-survey-in-japan
#11
Shinsuke Inoue, Mitsuhiro Kamiya, Makoto Nishihara, Young-Chang P Arai, Tatsunori Ikemoto, Takahiro Ushida
We conducted a cross-sectional, Internet-based survey with a nationally representative sample of Japanese adults to assess the prevalence and characteristics of failed back surgery syndrome (FBSS). Data regarding the residual symptoms and patient satisfaction from an online survey of 1842 lumbar surgery patients revealed the prevalence of FBSS to be 20.6% (95% confidence interval [CI], 18.8-22.6). The prevalence of low back pain, dull ache, numbness, cold sensations, and paresthesia after surgery was 94.0%, 71...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28405137/pleural-tuberculosis-following-infliximab-therapy-for-ankylosing-spondylitis
#12
V S Gokul Krishnan, Sharath Madhyastha, Kusugodlu Ramamoorthi, Raviraj V Acharya, Vinaya Gopalaswamy
We present a case of pleural tuberculosis (TB) in a patient on infliximab for ankylosing spondylitis. A 36-year-old male presented to our hospital with low back ache of inflammatory type along with multiple symmetric inflammatory type of joint pain. Further clinical examination, laboratory and radiological investigations were suggestive of ankylosing spondylitis. He was initially treated with nonsteroidal anti-inflammatory drugs but citing poor response it was decided to initiate biologic therapy using infliximab (antitumor necrosis factor-alpha)...
January 2017: Journal of Pharmacology & Pharmacotherapeutics
https://www.readbyqxmd.com/read/28278658/new-naphthalene-derivative-from-the-leaves-of-cassia-grandis-l
#13
Pham Thi Nhat Trinh, Ngoc Quoc Luan, Mai Dinh Tri, Vu Duy Khanh, Nguyen Huu An, Phan Nhat Minh, Pham Ngoc An, Nguyen Thi Le Thuy, Nguyen Kim Phi Phung, Le Tien Dung
Cassia grandis is used for the treatment of skin disorders, back pain, aches, etc. in Vietnamese traditional medicine. In this paper, phytochemicals of the leaves were investigated. A new naphthalene derivative (1, cassgranon D) and, seven known compounds rutin (2), afzelin (3), quercitrin (4), epicatechin (5), (-)-epiafzelechin (6), isoquercitrin (7) and aloe emodin (8) were isolated from the ethyl acetate and methanol extracts. Their structures were elucidated by spectral evidences (UV, IR, MS, (1)H, (13)C, DEPT, HSQC and HMBC NMR), as well as by comparing with published data...
August 2017: Natural Product Research
https://www.readbyqxmd.com/read/28191378/mediterranean-spotted-fever-a-rare-non-endemic-disease-in-the-usa
#14
Joshua Brad Oaks, Glenmore Lasam, Gina LaCapra
We report a case of a 43-year-old Israeli male who presented with an intermittent fever associated with a gradual appearance of diffusely scattered erythematous non-pruritic maculopapular lesions, generalized body malaise, muscle aches, and distal extremity weakness. He works in the Israeli military and has been exposed to dogs that are used to search for people in tunnels and claimed that he had removed ticks from the dogs. In the hospital, he presented with fever, a diffuse maculopapular rash, and an isolated round black eschar...
January 12, 2017: Curēus
https://www.readbyqxmd.com/read/28187075/investigating-the-association-between-lower-extremity-and-low-back-symptoms-among-saskatchewan-farmers-using-the-standardized-nordic-questionnaire
#15
Samuel Kwaku Essien, Catherine Trask, James Dosman, Brenna Bath
STUDY DESIGN: Cross sectional survey OBJECTIVE.: To investigated the association between self-reported low back symptoms and symptoms in the hip, knee, and ankle in a high-risk occupational group SUMMARY OF BACKGROUND DATA.: Low back pain, with or without lower extremity referral, poses a major challenge to occupational productivity, especially in farming. Although low back symptoms can occur independent of lower extremity symptoms, anatomical positioning of nerves supplying the lower limbs means structural and physiological changes in the spine can lead to referred pain in the lower limbs, but the magnitude of the association between low back and lower extremity symptoms is unclear...
February 9, 2017: Spine
https://www.readbyqxmd.com/read/28156595/scrambler-therapy-for-the-treatment-of-chronic-post-mastectomy-pain-cpmp-in-breast-cancer-survivors
#16
Charles L Loprinzi, Andrea L Cheville
253 Background: cPMP is chronic pain in the front thorax, axilla, and/or upper half of the arm beginning after mastectomy or lumpectomy persisting > 3 months after treatment and presents with pain, allodynia and disability. cPMP occurs in half of all patients with breast cancer and is severe in 13% (Gartner R JAMA 2009). Epidural bupivacaine, memantine, gabapentin or venlafaxine may help prevent cPMP, but there are no established proven treatments. (Shen J, Up to Date 2016) Scrambler therapy (ST) is an FDA-cleared treatment for neuropathic pain supported by multiple trials in over 800 patients with cancer pain, chemotherapy induced neuropathic pain, back pain, and post herpetic neuropathy (PHN)...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28125397/self-reported-wrist-and-finger-symptoms-associated-with-other-physical-mental-symptoms-and-use-of-computers-mobile-phones
#17
Leena Korpinen, Rauno Pääkkönen, Fabriziomaria Gobba
Recently, computer, mobile phone and Internet use has increased. This study aimed to determine the possible relation between self-reported wrist and finger symptoms (aches, pain or numbness) and using computers/mobile phones, and to analyze how the symptoms are specifically associated with utilizing desktop computers, portable computers or mini-computers and mobile phones. A questionnaire was sent to 15,000 working-age Finns (age 18-65). Via a questionnaire, 723 persons reported wrist and finger symptoms often or more with use...
March 1, 2017: International Journal of Occupational Safety and Ergonomics: JOSE
https://www.readbyqxmd.com/read/28054380/perceived-stress-recurrent-pain-and-aggregate-salivary-cortisol-measures-in-mid-adolescent-girls-and-boys
#18
Petra Lindfors, Lisa Folkesson Hellstadius, Viveca Östberg
Measures of perceived stress have been criticized for theoretical inconsistency. However, the validated pressure activation stress scale has been suggested as a theoretically sound alternative. But it is unclear how pressure and activation stress relate to objective and subjective measures including commonly used aggregate cortisol measures and health complaints respectively. Specifically, this study aimed at investigating how pressure and activation stress were related to aggregate salivary cortisol measures and recurrent pain in mid-adolescent girls and boys...
February 2017: Scandinavian Journal of Psychology
https://www.readbyqxmd.com/read/28041712/broken-heart-tako-tsubo-or-stress-cardiomyopathy-metaphors-meanings-and-their-medical-impact
#19
REVIEW
Thomas Efferth, Mita Banerjee, Norbert W Paul
The cardiac impact of psychological stress historically and socially understood as boundary experiences of human life has long since become an icon. From the aching heart to the sudden death provoked by awe, horror, grief, anger, and humiliation on one side and extreme enchantment, enthusiasm, and excitement on the other, the broken heart has become a globally recognized and powerful metaphor present from folklore to popular culture to high literature and back to everyday communication. In medicine, the "broken heart syndrome" is described as a relatively new nosological entity that has been used synonymously with the term tako-tsubo or stress cardiomyopathy...
March 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28012705/methodology-for-analyzing-environmental-quality-indicators-in-a-dynamic-operating-room-environment
#20
Thomas Gormley, Troy A Markel, Howard W Jones, Jennifer Wagner, Damon Greeley, James H Clarke, Mark Abkowitz, John Ostojic
BACKGROUND: Sufficient quantities of quality air and controlled, unidirectional flow are important elements in providing a safe building environment for operating rooms. METHODS: To make dynamic assessments of an operating room environment, a validated method of testing the multiple factors influencing the air quality in health care settings needed to be constructed. These include the following: temperature, humidity, particle load, number of microbial contaminants, pressurization, air velocity, and air distribution...
April 1, 2017: American Journal of Infection Control
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