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https://www.readbyqxmd.com/read/28405137/pleural-tuberculosis-following-infliximab-therapy-for-ankylosing-spondylitis
#1
V S Gokul Krishnan, Sharath Madhyastha, Kusugodlu Ramamoorthi, Raviraj V Acharya, Vinaya Gopalaswamy
We present a case of pleural tuberculosis (TB) in a patient on infliximab for ankylosing spondylitis. A 36-year-old male presented to our hospital with low back ache of inflammatory type along with multiple symmetric inflammatory type of joint pain. Further clinical examination, laboratory and radiological investigations were suggestive of ankylosing spondylitis. He was initially treated with nonsteroidal anti-inflammatory drugs but citing poor response it was decided to initiate biologic therapy using infliximab (antitumor necrosis factor-alpha)...
January 2017: Journal of Pharmacology & Pharmacotherapeutics
https://www.readbyqxmd.com/read/28278658/new-naphthalene-derivative-from-the-leaves-of-cassia-grandis-l
#2
Pham Thi Nhat Trinh, Ngoc Quoc Luan, Mai Dinh Tri, Vu Duy Khanh, Nguyen Huu An, Phan Nhat Minh, Pham Ngoc An, Nguyen Thi Le Thuy, Nguyen Kim Phi Phung, Le Tien Dung
Cassia grandis is used for the treatment of skin disorders, back pain, aches, etc. in Vietnamese traditional medicine. In this paper, phytochemicals of the leaves were investigated. A new naphthalene derivative (1, cassgranon D) and, seven known compounds rutin (2), afzelin (3), quercitrin (4), epicatechin (5), (-)-epiafzelechin (6), isoquercitrin (7) and aloe emodin (8) were isolated from the ethyl acetate and methanol extracts. Their structures were elucidated by spectral evidences (UV, IR, MS, (1)H, (13)C, DEPT, HSQC and HMBC NMR), as well as by comparing with published data...
February 16, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28191378/mediterranean-spotted-fever-a-rare-non-endemic-disease-in-the-usa
#3
Joshua Brad Oaks, Glenmore Lasam, Gina LaCapra
We report a case of a 43-year-old Israeli male who presented with an intermittent fever associated with a gradual appearance of diffusely scattered erythematous non-pruritic maculopapular lesions, generalized body malaise, muscle aches, and distal extremity weakness. He works in the Israeli military and has been exposed to dogs that are used to search for people in tunnels and claimed that he had removed ticks from the dogs. In the hospital, he presented with fever, a diffuse maculopapular rash, and an isolated round black eschar...
January 12, 2017: Curēus
https://www.readbyqxmd.com/read/28187075/investigating-the-association-between-lower-extremity-and-low-back-symptoms-among-saskatchewan-farmers-using-the-standardized-nordic-questionnaire
#4
Samuel Kwaku Essien, Catherine Trask, James Dosman, Brenna Bath
STUDY DESIGN: Cross sectional survey OBJECTIVE.: To investigated the association between self-reported low back symptoms and symptoms in the hip, knee, and ankle in a high-risk occupational group SUMMARY OF BACKGROUND DATA.: Low back pain, with or without lower extremity referral, poses a major challenge to occupational productivity, especially in farming. Although low back symptoms can occur independent of lower extremity symptoms, anatomical positioning of nerves supplying the lower limbs means structural and physiological changes in the spine can lead to referred pain in the lower limbs, but the magnitude of the association between low back and lower extremity symptoms is unclear...
February 9, 2017: Spine
https://www.readbyqxmd.com/read/28156595/scrambler-therapy-for-the-treatment-of-chronic-post-mastectomy-pain-cpmp-in-breast-cancer-survivors
#5
Charles L Loprinzi, Andrea L Cheville
253 Background: cPMP is chronic pain in the front thorax, axilla, and/or upper half of the arm beginning after mastectomy or lumpectomy persisting > 3 months after treatment and presents with pain, allodynia and disability. cPMP occurs in half of all patients with breast cancer and is severe in 13% (Gartner R JAMA 2009). Epidural bupivacaine, memantine, gabapentin or venlafaxine may help prevent cPMP, but there are no established proven treatments. (Shen J, Up to Date 2016) Scrambler therapy (ST) is an FDA-cleared treatment for neuropathic pain supported by multiple trials in over 800 patients with cancer pain, chemotherapy induced neuropathic pain, back pain, and post herpetic neuropathy (PHN)...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28125397/self-reported-wrist-and-finger-symptoms-associated-with-other-physical-mental-symptoms-and-use-of-computers-mobile-phones
#6
Leena Korpinen, Rauno Pääkkönen, Fabriziomaria Gobba
Recently, computer, mobile phone, and Internet use has increased. This study aimed to determine the possible relation between self-reported wrist and finger symptoms (aches, pain, or numbness) and using computers/mobile phones, and analyze how the symptoms are specifically associated with utilizing desktop computers, portable computers or mini-computers, and mobile phones. A questionnaire was sent to 15,000 working-age Finns (between the ages of 18-65). Via a questionnaire, 723 persons reported wrist and finger symptoms often or more...
January 26, 2017: International Journal of Occupational Safety and Ergonomics: JOSE
https://www.readbyqxmd.com/read/28054380/perceived-stress-recurrent-pain-and-aggregate-salivary-cortisol-measures-in-mid-adolescent-girls-and-boys
#7
Petra Lindfors, Lisa Folkesson Hellstadius, Viveca Östberg
Measures of perceived stress have been criticized for theoretical inconsistency. However, the validated pressure activation stress scale has been suggested as a theoretically sound alternative. But it is unclear how pressure and activation stress relate to objective and subjective measures including commonly used aggregate cortisol measures and health complaints respectively. Specifically, this study aimed at investigating how pressure and activation stress were related to aggregate salivary cortisol measures and recurrent pain in mid-adolescent girls and boys...
February 2017: Scandinavian Journal of Psychology
https://www.readbyqxmd.com/read/28041712/broken-heart-tako-tsubo-or-stress-cardiomyopathy-metaphors-meanings-and-their-medical-impact
#8
REVIEW
Thomas Efferth, Mita Banerjee, Norbert W Paul
The cardiac impact of psychological stress historically and socially understood as boundary experiences of human life has long since become an icon. From the aching heart to the sudden death provoked by awe, horror, grief, anger, and humiliation on one side and extreme enchantment, enthusiasm, and excitement on the other, the broken heart has become a globally recognized and powerful metaphor present from folklore to popular culture to high literature and back to everyday communication. In medicine, the "broken heart syndrome" is described as a relatively new nosological entity that has been used synonymously with the term tako-tsubo or stress cardiomyopathy...
March 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28012705/methodology-for-analyzing-environmental-quality-indicators-in-a-dynamic-operating-room-environment
#9
Thomas Gormley, Troy A Markel, Howard W Jones, Jennifer Wagner, Damon Greeley, James H Clarke, Mark Abkowitz, John Ostojic
BACKGROUND: Sufficient quantities of quality air and controlled, unidirectional flow are important elements in providing a safe building environment for operating rooms. METHODS: To make dynamic assessments of an operating room environment, a validated method of testing the multiple factors influencing the air quality in health care settings needed to be constructed. These include the following: temperature, humidity, particle load, number of microbial contaminants, pressurization, air velocity, and air distribution...
April 1, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/27922934/psychometric-properties-of-the-chinese-version-of-the-menopause-specific-quality-of-life-questionnaire
#10
Guangning Nie, Hongyan Yang, Jian Liu, ChunMei Zhao, Xiaoyun Wang
OBJECTIVE: The Menopause-Specific Quality-of-Life (MENQOL) questionnaire was developed as a specific tool to measure the health-related quality-of-life of postmenopausal women. Thus far, the Chinese version questionnaire has not been subjected to psychometric assessment with a large sample. This study aims to evaluate the validity and reliability of the Chinese version of the MENQOL specific to postmenopausal women in China. METHODS: A total of 1,137 menopausal symptomatic and 491 menopausal asymptomatic women from eight cities in China were recruited using a convenience sampling method...
December 5, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27922624/association-of-pain-social-support-and-socioeconomic-indicators-in-patients-with-spinal-cord-injury-in-iran
#11
Z Khazaeipour, E Ahmadipour, V Rahimi-Movaghar, F Ahmadipour, A R Vaccaro, B Babakhani
STUDY DESIGN: Descriptive cross-sectional study. OBJECTIVES: Pain is a prevalent complication of individuals with spinal cord injury (SCI). Our objective was to examine the association between social support, socioeconomic factors and psychosocial factors and pain to develop more effective management strategies. SETTING: Brain and Spinal Cord Injury Research (BASIR) Center, Tehran University of Medical Sciences, Tehran, Iran. METHODS: The Persian version of the Brief Pain Inventory was used to measure the pain, and the Multidimensional Scale of Perceived Social Support was used to measure social support through structured face-to-face interviews in SCI individuals...
February 2017: Spinal Cord
https://www.readbyqxmd.com/read/27891040/inadvertent-injection-of-potassium-chloride-instead-of-sodium-chloride-during-treatment-of-chronic-low-back-ache-with-epidural-injection-leading-to-paraplegia
#12
Rahul Ranjan, Naiyer Asif, Sohail Ahmad, Syed Ifthekar
Epidural injection of steroid is given for back pain resistant to other conservative management. Normal saline (NS) is used as diluent in 80 mg methylprednisolone and a local anesthetic. Due to a similar looking ampoule of NS and potassium chloride (KCl), there is a probability of accidental use of KCl instead of NS. We present a case of a 50-year-old male patient having low back ache refractory to other conservative treatments. Epidural injection of steroid was given, but accidently KCl was mixed with methylprednisolone instead of NS...
October 2016: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/27827987/self-reported-ache-pain-or-numbness-in-feet-and-use-of-computers-amongst-working-age-finns
#13
Leena Korpinen, Rauno Pääkkönen, Fabriziomaria Gobba
The use of the computers and other technical devices has increased. The aim of our work was to study the possible relation between self-reported foot symptoms and use of computers and cell phones using a questionnaire. The study was carried out as a cross-sectional study by posting a questionnaire to 15,000 working-age Finns. A total of 6121 responded, and 7.1% of respondents reported that they very often experienced pain, numbness, and aches in the feet. They also often experienced other symptoms: 52.3% had symptoms in the neck, 53...
November 7, 2016: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/27507101/novel-ligands-of-choline-acetyltransferase-designed-by-in-silico-molecular-docking-hologram-qsar-and-lead-optimization
#14
Rajnish Kumar, Bengt Långström, Taher Darreh-Shori
Recent reports have brought back the acetylcholine synthesizing enzyme, choline acetyltransferase in the mainstream research in dementia and the cholinergic anti-inflammatory pathway. Here we report, a specific strategy for the design of novel ChAT ligands based on molecular docking, Hologram Quantitative Structure Activity Relationship (HQSAR) and lead optimization. Molecular docking was performed on a series of ChAT inhibitors to decipher the molecular fingerprint of their interaction with the active site of ChAT...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27390459/yakson-touch-as-a-part-of-early-intervention-in-the-neonatal-intensive-care-unit-a-systematic-narrative-review
#15
REVIEW
Preeti Parashar, Asir John Samuel, Arpna Bansal, Vencita Priyanka Aranka
Yakson is a Korean therapeutic touch given to neonates and infants by caressing their abdomen with one hand while the other hand is placed on the back of the neonate\infant either to relieve their pain or to calm them down. It was traditionally used by Koreans by caressing the aching body part of their children with a belief that it would relieve their pain. In spite of clinical evidence of its usefulness, there is limited literature available on Yakson touch. A systematic narrative review (SNR) was undertaken on studies that were carried out on the effectiveness of Yakson touch on infants and neonates...
June 2016: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/27340538/sacral-insufficiency-fractures-mimicking-lumbar-spine-pathology
#16
G Sudhir, Kalra K L, Shankar Acharya, Rupinder Chahal
Sacral insufficiency fractures (SIFs) are a common cause of back pain in the elderly. SIFs mimic the symptoms of lumbar spine pathology and so are commonly missed or underdiagnosed. Here we present four cases of missed SIFs that were subsequently identified and treated. One patient was treated as mechanical lower back ache, another patient underwent root block and two patients underwent surgery for lumbar canal stenosis. None experienced relief of their symptoms after these procedures. Retrospective analysis of X-ray and magnetic resonance imaging data revealed SIFs that were confirmed by computed tomography scans...
June 2016: Asian Spine Journal
https://www.readbyqxmd.com/read/27313983/primary-squamous-cell-carcinoma-of-kidney-associated-with-large-calculus-in-non-functioning-kidney-a-case-report
#17
Sanjay Kumar, Vinay Tomar, Sher S Yadav, Hema Udawat, Shivam Priyadarshi, Nachiket Vyas, Neeraj Agarwal
Primary squamous cell carcinoma (SCC) of renal pelvis is a rare neoplasm. A 75-year old male presented with history of chronic dull aching pain in left flank region for last 10-years with history of left pyelolithotomy about 30-years back. After proper workup, large calculus with heterogeneous density mass detected in nonfunctioning left kidney. After radical nephrectomy, histopathological examination revealed squamous cell carcinoma of renal pelvis. SCC should be suspected in a patient with long history of renal calculous and associated mass in non functioning kidney...
September 2016: Urology Case Reports
https://www.readbyqxmd.com/read/27274270/orbital-metastasis-as-the-initial-presentation-of-lung-adenocarcinoma-a-case-report
#18
Liangchao Sun, Yali Qi, Xindong Sun, Jinming Yu, Xue Meng
Orbital metastasis as the initial presentation of lung adenocarcinoma is very rare, and so the lack of knowledge about this phenomenon can easily result in misdiagnosis, either as a orbital primary tumor or benign lesion. Here, we report a rare case in which the orbital symptom appeared first without any pulmonary manifestations. Our patient developed decreasing vision in his right eye over a 3-month duration. He then presented with proptosis and multiple aches from head to back. After systemic evaluation, our patient was diagnosed with Stage IV non-small-cell lung cancer and was managed with palliative chemoradiotherapy...
2016: OncoTargets and Therapy
https://www.readbyqxmd.com/read/27224742/varicella-zoster-virus-triggers-the-immunopathology-of-giant-cell-arteritis
#19
Don Gilden, Maria A Nagel
PURPOSE OF REVIEW: Giant cell arteritis (GCA) is a severe form of vasculitis in the elderly. The recent discovery of varicella zoster virus (VZV) in the temporal arteries and adjacent skeletal muscle of patients with GCA, and the rationale and strategy for antiviral and corticosteroid treatment for GCA are reviewed. RECENT FINDINGS: The clinical features of GCA include excruciating headache/head pain, often with scalp tenderness, a nodular temporal arteries and decreased temporal artery pulsations...
July 2016: Current Opinion in Rheumatology
https://www.readbyqxmd.com/read/27210844/effect-of-butler-s-neural-tissue-mobilization-and-mulligan-s-bent-leg-raise-on-pain-and-straight-leg-raise-in-patients-of-low-back-ache
#20
Neha Tambekar, Shaila Sabnis, Apoorva Phadke, Nilima Bedekar
Low back ache (LBA) is a common musculoskeletal disorder sometimes associated with a positive limited Straight leg raise (SLR) test. Mulligan's bent leg raise (BLR) and Butler's neural tissue mobilization (NTM) are commonly used techniques for the treatment of low back ache where SLR is limited. The aim of this study was to evaluate the effect of both the techniques on pain and limited SLR in patients with LBA. Thirty one patients with LBA with radiculopathy were randomly allocated into 2 groups; BLR [n = 16] NTM [n = 15]...
April 2016: Journal of Bodywork and Movement Therapies
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