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JOURNAL ARTICLE
Maria C Sighinolfi, Tommaso Calcagnile, Marco Ticonosco, Shaniko Kaleci, Stefano DI Bari, Simone Assumma, Luca Sarchi, Enrico Panio, Riccardo Ferrari, Adele Piro, Alberto Ragusa, Silvia Ciarlariello, Rodrigo D DA Silva, Roberto LA Rocca, Ester Illiano, Alessio Paladini, Francesco Persico, Davide Giraudo, Enrico DE Marzo, Riccardo Grisanti, Guglielmo Mantica, Esteban Emiliani, Massimo Madonia, Michele Salvetti, Pierfrancesco Bassi, Emanuele Montanari, Pierluigi Bove, Alchiede Simonato, Timothy D Averch, Francesco Porpiglia, Alessandro Calarco, Sebastiano Bruschetta, Fabio Manferrari, Francisco P Daels, Maria A Cerruto, Alessandro Antonelli, Giorgio Mazzon, Antonio Celia, Claudio Simeone, Stefano Zaramella, Alberto Saita, Elisabetta Costantini, Ettore Mearini, Mauro DE Dominicis, Vincenzo Mirone, Fernando J Kim, Stefania Ferretti, Stefano Puliatti, Bernardo Rocco, Salvatore Micali
BACKGROUND: Stone nomogram by Micali et al., able topredict treatment failure of shock-wave lithotripsy (SWL), retrograde intrarenal surgery (RIRS) and percutaneous nephrolithotomy (PNL) in the management of single 1-2 cm renal stones, was developed on 2605 patients and showed a high predictive accuracy, with an area under ROC curve of 0.793 at internal validation. The aim of the present study is to externally validate the model to assess whether it displayed a satisfactory predictive performance if applied to different populations...
May 10, 2024: Minerva urology and nephrology
#2
REVIEW
Juan Ramón Cano, José Manuel Bogallo, Alicia Ramirez, Enrique Guerado
The diagnosis of a traumatic unstable pelvis in a stable patient is a temporary concept depending on when we see the patient, as all patients presenting with hemorrhagic shock have hemodynamic stability until they become unstable. As a rule, the more unstable the pelvic fracture is, the higher the risk of bleeding and hemodynamic instability it has. Therefore, in unstable pelvic fractures, hemodynamic stability should be a diagnosis by exclusion. For bleeding detection in stable patients, an immediate one-stage contrast-enhanced CT scan is the appropriate diagnosis test; however, since CT scan radiation is always an issue, X-rays should be considered in those cases of hemodynamically stable patients in whom there is a reasonable suspicion that no unsafe bleeding is going on...
May 10, 2024: EFORT Open Reviews
#3
Yang Yang, Enhe Liu, Xijian Zhang, Lichun Wang, Lei Chen
BACKGROUND: Fournier's gangrene (FG) is a severe form of necrotizing fasciitis primarily caused by gram-negative bacteria. FG can rapidly progress to septic shock, resulting in high mortality rates. In the past, the management of the inflammatory response caused by gram-negative bacteria has been limited. Continuous Veno-Venous Hemofiltration with oXiris hemofilters (oXiris-CVVH) has shown promise in adsorbing inflammatory factors and endotoxins, making it an attractive approach for treating FG...
May 15, 2024: Heliyon
#4
Ahmed A Al Bazroon, Ahmed A Albassri, Tarek Swellam, Ibrahim Al Basha
Extracorporeal shock wave lithotripsy (ESWL) is considered a safe, reliable, and non-invasive modality for kidney stone management. However, there are well-established complications related to ESWL documented in the literature in the form of renal and extrarenal complications. Skeletal complications related to ESWL are rarely recorded; as far as we know, there is only one documented case report of an ESWL-related burst vertebral fracture seen in an osteoporotic patient, diagnosed as granulomatous spondylitis...
April 2024: Curēus
#5
REVIEW
Arif Albulushi, Ahmed Tawfek, Hatim Al Lawatia
OBJECTIVE: This systematic review aims to assess the comparative effectiveness and safety of temporary mechanical circulatory support (MCS) devices in various subgroups of patients with acute cardiogenic shock, providing insights for personalized clinical decision-making. METHODS: We conducted a comprehensive search across major databases to identify studies that reported on the use of temporary MCS devices like TandemHeart, Impella, and VA-ECMO in acute cardiogenic shock...
May 7, 2024: Current Problems in Cardiology
#6
JOURNAL ARTICLE
Cemre Ipek Esen, Salim Satar, Muge Gulen, Selen Acehan, Sarper Sevdımbas, Cagdas Ince
Perfusion index (PI) is a promising indicator for monitoring peripheral perfusion. The present study aimed to compare the efficiency of PI and PESI score in estimating the 30-day mortality and treatment needs of patients diagnosed with pulmonary embolism in the emergency department. This study was prospective and observational. The demographic features of the patients, comorbidities, vital signs, PESI score, PI, treatment applied to the patient and airway management, right ventricular diameter/left ventricular diameter ratio, length of hospital stay, outcome, and 30-day mortality were recorded...
May 8, 2024: Internal and Emergency Medicine
#7
JOURNAL ARTICLE
Maki Murata, Sayaka Shimizu, Ryohei Yamamoto, Tsukasa Kamitani, Hajime Yamazaki, Yusuke Ogawa, Shunichi Fukuhara, Hideto Yasuda, Yosuke Yamamoto
Objectives The Clinical Practice Guidelines for the Management of Sepsis and Septic Shock weakly recommend steroids for septic shock resistant to fluid resuscitation and vasopressors. This study aimed to describe the clinical practices for septic shock in the real world and to compare the association between the intermittent or continuous infusion of steroids and the prognosis. Methods This was a retrospective cohort study based on the AMOR-VENUS, in which Japanese intensive care unit (ICU) inpatients were enrolled between January and March 2018...
May 9, 2024: Internal Medicine
#8
JOURNAL ARTICLE
Moeko Omiya, Yusuke Morii, Masako Mukai, Yuya Mitsuhashi, Ken Kato, Toshiaki Isogai
A man in his 80s with myasthenia gravis (MG) developed dysmobility and chest discomfort. An electrocardiogram revealed ST-segment elevation, and coronary angiography revealed Takotsubo syndrome (TTS). He experienced myasthenic crisis that required ventilation and shock that was refractory to vasopressors and required intra-aortic balloon pump (IABP) insertion. He was managed conservatively without MG-specific treatment until his hemodynamics improved. On hospital day 6, he was weaned from IABP. MG is a high-risk condition for TTS, and TTS with MC is associated with high mortality...
May 9, 2024: Internal Medicine
#9
JOURNAL ARTICLE
Jessica Saliba, Claire Vassallo, Joseph Saliba, Michael Pace Bardon
We present the case of a man in his early 50s who presented with a history of fever, malaise and jaundice. Initial investigations showed liver and renal dysfunction with no discernible cause for the septic process. On starting intravenous antibiotics, the patient developed a septic-shock-like reaction requiring transfer to intensive care. A diagnosis of leptospirosis was eventually established through an extensive and thorough history leading to a stepwise approach to investigations. Treatment targeting leptospirosis was delivered with noticeable clinical improvement...
May 7, 2024: BMJ Case Reports
#10
JOURNAL ARTICLE
Dominga Ladevig, Valentina Veloso, Camila Ávila-Oliver
INTRODUCTION: Trigeminal neuralgia is a painful neuropathic disorder characterized by sudden electric shock-like pain that significantly impacts patients' quality of life. Multiple treatment alternatives are available, including medical and surgical options but establishing the optimal course of action can be challenging. To enhance clinical decision-making for trigeminal neuralgia treatment, it is imperative to organize, describe and map the available systematic reviews and randomized trials...
May 8, 2024: Medwave
#11
JOURNAL ARTICLE
Xiali Xue, Qingfa Song, Xinwei Yang, Amila Kuati, Hao Fu, Guoqing Cui
BACKGROUND: Rotator cuff injury (RCI) is a common musculoskeletal ailment and a major cause of shoulder pain and limited functionality. The ensuing pain and restricted movement significantly impact overall quality of life. This study aims to systematically review the effects of extracorporeal shock wave therapy (ESWT) on RCI. METHODS: This protocol follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols. A literature search, spanning inception to November 1, 2023, will include databases such as PubMed, Web of Science, the Cochrane Library, Scopus, MEDLINE, EMBASE, EBSCO, and China National Knowledge Infrastructure (CNKI) to identify ESWT studies for RCI treatment...
2024: PloS One
#12
JOURNAL ARTICLE
Antoine Bois, Yara Abi Zeid Daou, Naoto Watanabe, Ali Jendoubi, Fanny Lidouren, Estelle Faucher, Nadir Mouri, Bijan Ghaleh, Guillaume Geri, Renaud Tissier, Matthias Kohlhauer
BACKGROUND: Post-cardiac arrest (CA) shock is associated with multiple organ failure, including acute kidney injury, and is the leading cause of early death among patient successfully resuscitated from CA. Arginine-vasopressin (AVP) may be an interesting therapeutic alternative or complement to noradrenaline (NAD) to both control shock and preserve regional, especially renal, organ perfusions. METHODS: 18 swine (24-39 kg) were submitted to 14 min of ventricular fibrillation and cardio-pulmonary resuscitation...
June 2024: Resuscitation plus
#13
REVIEW
Ehmaidy Al Qaf'an, Stewart Alford, Kimberley Porteous, David Lim
Background . Throughout history, communities have faced outbreaks of infectious diseases and other natural and man-made disasters that pose significant threats to lives, public health, and business continuity. Many of these disasters are crises that require critical decisions to be made in a short, crucial time with limited information and unforeseen circumstances amidst panic, fear, and shock. The COVID-19 pandemic is a recent example, with public leaders responding to and formulating strategies to attenuate the relentless waves of transmission and surges in resource demands...
2024: Emergency Medicine International
#14
Georgia Karmioti, Stefanos Sakellaropoulos, Inan Sarikaya, Antonia Kastoris, Christina Hadjilouka, Christos Efseviou, Michael Myrianthefs, Andreas Mitsis
Pheochromocytoma-induced Takotsubo cardiomyopathy is a rare but life-threatening condition, caused by excessive plasma catecholamine levels, resulting in acute myocardial dysfunction. Clinical presentation includes a rapid development of heart failure due to regional wall motion abnormalities (most commonly affecting all mid to apical left ventricle (LV) wall segments) causing the "octopus-trap-like" LV shape. A 45-year-old female patient presented with acute cardiogenic shock of non-ischemic etiology. Her past medical history included a similar episode, which was followed by full recovery, but at this admission she required hemodynamic support with venoarterial extracorporeal membrane oxygenation...
May 2024: Journal of Medical Cases
#15
Davis Frease, David Rico Mora
Trisomy 18 is the second most common autosomal trisomy aside from trisomy 21. Anesthesiologists were unlikely to manage such patients in the past, specifically those surviving later into childhood due to the 90% mortality rate within the first year of life and the lack of procedural options that were available. However, a paucity of literature regarding the anesthetic management of such patients exists. Trisomy 18 patients present a unique anesthetic challenge, given the presence of associated dysmorphic facial features and the involvement of multiple organ systems, leading to difficult airway and hemodynamic disturbances...
May 2024: Journal of Medical Cases
#16
JOURNAL ARTICLE
Huan Zhou, Yousaf Gul, Yasir Hameed, Majid Alhomrani, Saleh A Alghamdi, Abdulraheem Ali Almalki, Meshari A Alsuwat, Naif ALSuhaymi, Rida Naz, Guang Chen
BACKGROUND: Osteoporosis (OP) stands as a prevalent bone ailment affecting the elderly, globally. The identification of reliable diagnostic markers crucially aids OP clinical management. METHODS: Utilizing the GEO database (GSE35959), we acquired expression profiles for OP and normal samples. Differential expression genes (DEGs) and hub genes were pinpointed through STRING, GEO2R, and Cytoscape. The competing endogenous RNA (ceRNA) network was constructed using miRTarBase, miRDB, and MiRcode databases...
2024: American Journal of Translational Research
#17
JOURNAL ARTICLE
Maya Avraham, György Sinkovits, Lisa Hurler, Zoltán Prohászka, Zvi Fishelson
BACKGROUND: Mortalin/GRP75 is a ubiquitous mitochondrial chaperone related to the cytosolic heat shock protein 70. It protects cells from various types of damages and from senescence. Our goal was to determine whether COVID-19 patients have circulating mortalin in their blood and to assess its prognostic value in anticipating disease severity. METHODS: Mortalin was determined by ELISA in the sera of 83 COVID-19 patients enrolled in the study. Patients were categorized into 4 groups: critical patients who died (FATAL) or required intensive care and survived (ICU), patients of mild severity (hospitalized but not critical) who required nasal oxygen support (HOSP+O2 ), and patients who did not need oxygen therapy (HOSP)...
2024: Frontiers in Immunology
#18
JOURNAL ARTICLE
X F Xu, L Kou, Y Chen, Z C Zeng, Q Li, Q Ye, J L Zhang
Objective: To examine the perioperative clinical features and prognosis of patients with ruptured abdominal aortic aneurysms (rAAA) who received surgical repair. Methods: The clinical data of rAAA patients who underwent surgical repair and were admitted to the Surgical Intensive Care Unit of Beijing Anzhen Hospital, Capital Medical University from August 2005 to November 2020 were retrospectively analyzed, including the general clinical features, surgical mode, intraoperative conditions, postoperative complications, and fatality rate...
May 1, 2024: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
#19
JOURNAL ARTICLE
Rui He, Kebiao Zhang, Hong Li, Shimin Fu, Zhen Chen, Manping Gu
AIM: This study was designed to investigate the association between Charlson Comorbidity Index (CCI) and in-hospital mortality and other clinical outcomes among patients with hyperglycemic crises. METHOD: This retrospective cohort study was conducted using data from electric medical records. A total of 1668 diabetic patients with hyperglycemic crises from six tertiary hospitals met the inclusion criteria. CCI < 4 was defined as low CCI and CCI ≥ 4 was defined as high CCI...
May 7, 2024: Journal of Evaluation in Clinical Practice
#20
JOURNAL ARTICLE
Oliver Coyle, Vance T Vredenburg, Jonathon H Stillman
Organisms within freshwater and marine environments are subject to a diverse range of often co-occurring abiotic and biotic stressors. Despite growing awareness of the complex multistress systems at play in aquatic ecosystems, many questions remain regarding how simultaneous stressors interact with one another and jointly impact aquatic species. We looked at multistress interactions in a protected stream ecosystem in Mendocino County, California. Specifically, we examined how diurnal temperature variation, turbidity, and predator cues altered the movement speed of larval Pacific giant salamanders ( Dicamptodon tenebrosus )...
May 2024: Ecology and Evolution
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