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Barbara J Deal

Vicki S Conn, Cindy M Anderson, Cheryl Killion, Barbara Bowers, Jean F Wyman, Linda M Herrick, Julie J Zerwic, Carol E Smith, Marlene Z Cohen, Lazelle E Benefield, Robert Topp, Nancy L Fahrenwald, Marita Titler, Janet L Larson, Maureen M Varty, Urmeka T Jefferson
Junior faculty follow a research path replete with challenges as they strive to create knowledge in their area of interest while balancing new responsibilities. Unlike graduate school, where students focus inward on personal development, junior faculty must add responsibilities in ways that hold them accountable as members of a university. This special article deals with three themes of interest to new junior faulty launching research programs: personal development, collaboration and team development within university settings, and funding advice...
August 1, 2017: Western Journal of Nursing Research
Stuart O J Crichton, Sascha M Kirchner, Victoria Porley, Stefanie Retz, Gardis von Gersdorff, Oliver Hensel, Barbara Sturm
Initial quality grading of meat is generally carried out using invasive and occasionally destructive sampling for the purposes of pH testing. Precise pH and thresholds exist to allow the classification of different statuses of meat, e.g. for detection of dry, firm, and dark (DFD) (when dealing with cattle and sheep), or pale, soft exudative meat (when dealing with pork). This paper illustrates that threshold detection for pH level in beef with different freshness levels (fresh, fresh frozen-thawed, matured, and matured frozen-thawed)...
July 18, 2017: Meat Science
Kara Harrington, Claire T Boyle, Kellee M Miller, Marisa E Hilliard, Barbara J Anderson, Michelle Van Name, Linda A DiMeglio, Lori M Laffel
No abstract text is available yet for this article.
February 1, 2017: Journal of Diabetes Science and Technology
Barbara D Goss, Anna T Ryan, Joshua Waring, Terry Judd, Neville G Chiavaroli, Richard Charles O'Brien, Stephen C Trumble, Geoffrey J McColl
PROBLEM: Professionalism is a critical attribute of medical graduates. Its measurement is challenging. The authors sought to assess final-year medical students' knowledge of appropriate professional behavior across a broad range of workplace situations. APPROACH: Situational judgement tests (SJTs) are used widely in applicant selection to assess judgement or decision making in work-related settings as well as attributes such as empathy, integrity, and resilience...
June 2017: Academic Medicine: Journal of the Association of American Medical Colleges
Joe N Perry, Paolo Barberi, Detlef Bartsch, A N E Birch, Achim Gathmann, Jozsef Kiss, Barbara Manachini, Marco Nuti, Stefan Rauschen, Joachim Schiemann, Mechthild Schuppener, Jeremy Sweet, Christoph C Tebbe, Fabio Veronesi
We respond to the paper of Kruse-Plass et al. (Environ Sci Eur 29:12, 2017), published in this journal, regarding the risk to non-target lepidopteran larvae exposed to pollen from one or more of three Bt maize events (MON810, Bt11 and 1507). We emphasise that what is important for environmental risk assessment is not the number of pollen grains per se, but the degree of exposure of a NT lepidopteran larva to Bt protein contained in maize pollen. The main text of this response deals with general issues which Kruse-Plass et al...
2017: Environmental Sciences Europe
Barbara J Deal, Constantine Mavroudis
Patients with repaired or unrepaired congenital heart anomalies are at increased risk for arrhythmia development throughout their lives, often paralleling the need for reoperations for hemodynamic residua. The ability to incorporate arrhythmia surgery into reoperations can result in improvement in functional class and decreased need for antiarrhythmic medications. Every reoperation for congenital heart disease can be viewed as an opportunity to assess the electrical and arrhythmia substrates and to intervene to improve the arrhythmias and the hemodynamic condition of the patient...
June 2017: Cardiac Electrophysiology Clinics
Barbara J Turner, Kathryn Craig, Vidhi S Makanji, Bertha E Flores, Ludivina Hernandez
AIMS AND OBJECTIVES: To identify support needs of low-income baby boomers recently diagnosed with chronic hepatitis C virus infection. BACKGROUND: The U.S. Preventive Services Task Force has endorsed one-time screening of all baby boomers (born 1945-1965) for hepatitis C because 75% of the estimated 2-3 million persons with chronic infection are in this age range. We hypothesised that persons diagnosed by routine screening would have significant psycho-emotional, cognitive and healthcare challenges that need to be met by collaborative care and services from nurses and other healthcare personnel...
March 15, 2017: Journal of Clinical Nursing
Bradley S Marino, David J Goldberg, Adam L Dorfman, Eileen King, Heidi Kalkwarf, Babette S Zemel, Margaret Smith, Jesse Pratt, Mark A Fogel, Amanda J Shillingford, Barbara J Deal, Anitha S John, Caren S Goldberg, Timothy M Hoffman, Marshall L Jacobs, Asher Lisec, Susan Finan, Lazaros K Kochilas, Thomas W Pawlowski, Kathleen Campbell, Clinton Joiner, Stuart L Goldstein, Paul Stephens, Alvin J Chin
BACKGROUND: Fontan survivors have depressed cardiac index that worsens over time. Serum biomarker measurement is minimally invasive, rapid, widely available, and may be useful for serial monitoring. The purpose of this study was to identify biomarkers that correlate with lower cardiac index in Fontan patients. Methods and results This study was a multi-centre case series assessing the correlations between biomarkers and cardiac magnetic resonance-derived cardiac index in Fontan patients ⩾6 years of age with biochemical and haematopoietic biomarkers obtained ±12 months from cardiac magnetic resonance...
January 2017: Cardiology in the Young
Barbara D Goss, Anna T Ryan, Joshua Waring, Terry Judd, Neville G Chiavaroli, Richard Charles O'Brien, Stephen C Trumble, Geoffrey J McColl
PROBLEM: Professionalism is a critical attribute of medical graduates. Its measurement is challenging. The authors sought to assess final-year medical students' knowledge of appropriate professional behavior across a broad range of workplace situations. APPROACH: Situational judgement tests (SJTs) are used widely in applicant selection to assess judgement or decision making in work-related settings as well as attributes such as empathy, integrity, and resilience...
February 21, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
Constantine Mavroudis, Barbara J Deal
Certain congenital heart anomalies make patients more susceptible to arrhythmia development throughout their lives. This poses the question whether prophylactic arrhythmia surgery should be incorporated into reparative open heart procedures for congenital heart disease. There is currently no consensus on what constitutes a standard prophylactic procedure, owing to the questions that remain regarding lesions to be performed; energy sources to use; proximity of energy source or incisions to coronary arteries, sinoatrial node, atrioventricular node; circumstances for right atrial, left atrial, or biatrial appendectomy; and whether to perform a right, left, or biatrial maze procedure...
July 2016: Translational pediatrics
Angela M Barbara, Maureen Dobbins, R Brian Haynes, Alfonso Iorio, John N Lavis, Anthony J Levinson
BACKGROUND: Evidence summaries and blogs can support evidence-informed healthy aging, by presenting high-quality health research evidence in plain language for a nonprofessional (citizen) audience. OBJECTIVE: Our objective was to explore citizens' perceptions about the usability of evidence summaries and blog posts on the Web-based McMaster Optimal Aging Portal. METHODS: Twenty-two citizens (aged 50 years and older) and informal caregivers participated in a qualitative study using a think-aloud method and semistructured interviews...
August 19, 2016: JMIR Human Factors
Barbara L Filkins, Ju Young Kim, Bruce Roberts, Winston Armstrong, Mark A Miller, Michael L Hultner, Anthony P Castillo, Jean-Christophe Ducom, Eric J Topol, Steven R Steinhubl
The rapid growth in the availability and incorporation of digital technologies in almost every aspect of our lives creates extraordinary opportunities but brings with it unique challenges. This is especially true for the translational researcher, whose work has been markedly enhanced through the capabilities of big data aggregation and analytics, wireless sensors, online study enrollment, mobile engagement, and much more. At the same time each of these tools brings distinctive security and privacy issues that most translational researchers are inadequately prepared to deal with despite accepting overall responsibility for them...
2016: American Journal of Translational Research
Eileen Broomall, Mary E McBride, Barbara J Deal, Laurence Ducharme-Crevier, Alexandra Shaw, Mjaye Mazwi, Carl L Backer, Michael C Mongé, John Costello, Bradley S Marino, Andrew DeFreitas, Mark S Wainwright
BACKGROUND: Palliative procedures performed before the Fontan procedure may require ligation of the subclavian arteries, thereby affecting flow to the vertebral arteries. In adults with functionally univentricular heart disease, the implications of altered brainstem vascular anatomy for perioperative management of failing Fontan circulation are not known. METHODS: We identified abnormal posterior circulation anatomy in an adult patient with failing Fontan circulation who experienced a brainstem stroke after Fontan conversion...
June 2016: Annals of Thoracic Surgery
Jana Lichtenfeld, Barbara J Deal, Susan Crawford
Anabolic androgenic steroids are synthetic derivatives of testosterone that promote the growth of skeletal muscles and have many recognised cardiovascular effects. We report the clinical presentation and pathological findings of an adolescent male whose sudden cardiac arrest following ventricular fibrillation was attributed to anabolic androgenic steroid use. The age of our patient reflects the usage of anabolic androgenic steroids among younger athletes and highlights the need for increased awareness among practitioners...
June 2016: Cardiology in the Young
Constantine Mavroudis, Barbara J Deal
Early survival after the Fontan operation has improved significantly leading to a lifetime of Fontan circulation for patients. There is a natural progression of pulmonary artery pressure during the human lifetime that is easily tolerated in two-ventricle physiology but is deleterious for single-ventricle physiology. Obstructions in the venous to pulmonary artery pathway and pulmonary venous return or ventricular outflow, atrioventricular valve dysfunction (regurgitation), pulmonary arteriovenous malformations, venous thrombosis, and the development of atrial arrhythmias can lead to reduced functional status...
March 2016: World Journal for Pediatric & Congenital Heart Surgery
Barbara A Head, Tara J Schapmire, Lori Earnshaw, John Chenault, Mark Pfeifer, Susan Sawning, Monica A Shaw
The needs of an aging population and advancements in the treatment of both chronic and life-threatening diseases have resulted in increased demand for quality palliative care. The doctors of the future will need to be well prepared to provide expert symptom management and address the holistic needs (physical, psychosocial, and spiritual) of patients dealing with serious illness and the end of life. Such preparation begins with general medical education. It has been recommended that teaching and clinical experiences in palliative care be integrated throughout the medical school curriculum, yet such education has not become the norm in medical schools across the world...
2016: Advances in Medical Education and Practice
Timothy J Geddes, Billie E Ketelsen, Samreen Ahmed, Barbara L Pruetz, Laura E Fortier
Given the high demands on a multidisciplinary approach to sample collection, and despite the rigorous quality assurance and quality control measures designed to minimize sample misidentification in our state of the art biorepository, the potential for error is still a concern. Measures to deal with potential uncertainties are a necessary part of every successful biobanking operation. The Beaumont BioBank and associated Core Molecular Laboratory have developed procedures to address these rare incidents. Here we present a case study of occurrences in the Beaumont BioBank in which the identity of samples was uncertain and a resolution workflow was implemented to quickly remove the ambiguity...
February 2016: Biopreservation and Biobanking
Tyler S Alioto, Ivo Buchhalter, Sophia Derdak, Barbara Hutter, Matthew D Eldridge, Eivind Hovig, Lawrence E Heisler, Timothy A Beck, Jared T Simpson, Laurie Tonon, Anne-Sophie Sertier, Ann-Marie Patch, Natalie Jäger, Philip Ginsbach, Ruben Drews, Nagarajan Paramasivam, Rolf Kabbe, Sasithorn Chotewutmontri, Nicolle Diessl, Christopher Previti, Sabine Schmidt, Benedikt Brors, Lars Feuerbach, Michael Heinold, Susanne Gröbner, Andrey Korshunov, Patrick S Tarpey, Adam P Butler, Jonathan Hinton, David Jones, Andrew Menzies, Keiran Raine, Rebecca Shepherd, Lucy Stebbings, Jon W Teague, Paolo Ribeca, Francesc Castro Giner, Sergi Beltran, Emanuele Raineri, Marc Dabad, Simon C Heath, Marta Gut, Robert E Denroche, Nicholas J Harding, Takafumi N Yamaguchi, Akihiro Fujimoto, Hidewaki Nakagawa, Víctor Quesada, Rafael Valdés-Mas, Sigve Nakken, Daniel Vodák, Lawrence Bower, Andrew G Lynch, Charlotte L Anderson, Nicola Waddell, John V Pearson, Sean M Grimmond, Myron Peto, Paul Spellman, Minghui He, Cyriac Kandoth, Semin Lee, John Zhang, Louis Létourneau, Singer Ma, Sahil Seth, David Torrents, Liu Xi, David A Wheeler, Carlos López-Otín, Elías Campo, Peter J Campbell, Paul C Boutros, Xose S Puente, Daniela S Gerhard, Stefan M Pfister, John D McPherson, Thomas J Hudson, Matthias Schlesner, Peter Lichter, Roland Eils, David T W Jones, Ivo G Gut
As whole-genome sequencing for cancer genome analysis becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is required. Here using tumour-normal sample pairs from two different types of cancer, chronic lymphocytic leukaemia and medulloblastoma, we conduct a benchmarking exercise within the context of the International Cancer Genome Consortium. We compare sequencing methods, analysis pipelines and validation methods. We show that using PCR-free methods and increasing sequencing depth to ∼ 100 × shows benefits, as long as the tumour:control coverage ratio remains balanced...
December 9, 2015: Nature Communications
Barbara J Deal, John M Costello, Gregory Webster, Sabrina Tsao, Carl L Backer, Constantine Mavroudis
BACKGROUND: Atrial arrhythmias and progressive circulatory failure frequently develop in patients with a Fontan circulation. Improvement of flow dynamics and revision of the arrhythmia substrate may improve outcomes in selected patients. We sought to determine intermediate-term outcomes after Fontan conversion with arrhythmia operations and identify characteristics associated with decreased transplant-free survival. METHODS: The first 140 Fontan conversions with arrhythmia operations at a single institution were analyzed for predictors of cardiac death or transplant and incidence of arrhythmia recurrence...
February 2016: Annals of Thoracic Surgery
Michael J Beran, Bonnie M Perdue, Barbara A Church, J David Smith
Metacognition refers to thinking about thinking, and there has been a great deal of interest in how this ability manifests across primates. Based on much of the work to date, a tentative division has been drawn with New World monkeys on 1 side and Old World monkeys and apes on the other. Specifically, Old World monkeys, apes, and humans often show patterns reflecting metacognition, but New World monkeys typically do not, or show less convincing behavioral patterns. However, recent data suggest that this difference may relate to other aspects of some experimental tasks...
January 2016: Journal of Experimental Psychology. Animal Learning and Cognition
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