keyword
MENU ▼
Read by QxMD icon Read
search

Barbara J Deal

keyword
https://www.readbyqxmd.com/read/27709096/prophylactic-arrhythmia-surgery-in-association-with-congenital-heart-disease
#1
Constantine Mavroudis, Barbara J Deal
Certain congenital heart anomalies make patients more susceptible to arrhythmia development throughout their lives. This poses the question whether prophylactic arrhythmia surgery should be incorporated into reparative open heart procedures for congenital heart disease. There is currently no consensus on what constitutes a standard prophylactic procedure, owing to the questions that remain regarding lesions to be performed; energy sources to use; proximity of energy source or incisions to coronary arteries, sinoatrial node, atrioventricular node; circumstances for right atrial, left atrial, or biatrial appendectomy; and whether to perform a right, left, or biatrial maze procedure...
July 2016: Translational pediatrics
https://www.readbyqxmd.com/read/27542995/user-experiences-of-the-mcmaster-optimal-aging-portal-s-evidence-summaries-and-blog-posts-usability-study
#2
Angela M Barbara, Maureen Dobbins, R Brian Haynes, Alfonso Iorio, John N Lavis, Anthony J Levinson
BACKGROUND: Evidence summaries and blogs can support evidence-informed healthy aging, by presenting high-quality health research evidence in plain language for a nonprofessional (citizen) audience. OBJECTIVE: Our objective was to explore citizens' perceptions about the usability of evidence summaries and blog posts on the Web-based McMaster Optimal Aging Portal. METHODS: Twenty-two citizens (aged 50 years and older) and informal caregivers participated in a qualitative study using a think-aloud method and semistructured interviews...
2016: JMIR Human Factors
https://www.readbyqxmd.com/read/27186282/privacy-and-security-in-the-era-of-digital-health-what-should-translational-researchers-know-and-do-about-it
#3
Barbara L Filkins, Ju Young Kim, Bruce Roberts, Winston Armstrong, Mark A Miller, Michael L Hultner, Anthony P Castillo, Jean-Christophe Ducom, Eric J Topol, Steven R Steinhubl
The rapid growth in the availability and incorporation of digital technologies in almost every aspect of our lives creates extraordinary opportunities but brings with it unique challenges. This is especially true for the translational researcher, whose work has been markedly enhanced through the capabilities of big data aggregation and analytics, wireless sensors, online study enrollment, mobile engagement, and much more. At the same time each of these tools brings distinctive security and privacy issues that most translational researchers are inadequately prepared to deal with despite accepting overall responsibility for them...
2016: American Journal of Translational Research
https://www.readbyqxmd.com/read/27016841/posterior-circulation-ischemia-or-occlusion-in-five-adults-with-failing-fontan-circulation
#4
Eileen Broomall, Mary E McBride, Barbara J Deal, Laurence Ducharme-Crevier, Alexandra Shaw, Mjaye Mazwi, Carl L Backer, Michael C Mongé, John Costello, Bradley S Marino, Andrew DeFreitas, Mark S Wainwright
BACKGROUND: Palliative procedures performed before the Fontan procedure may require ligation of the subclavian arteries, thereby affecting flow to the vertebral arteries. In adults with functionally univentricular heart disease, the implications of altered brainstem vascular anatomy for perioperative management of failing Fontan circulation are not known. METHODS: We identified abnormal posterior circulation anatomy in an adult patient with failing Fontan circulation who experienced a brainstem stroke after Fontan conversion...
June 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/26980272/sudden-cardiac-arrest-following-ventricular-fibrillation-attributed-to-anabolic-steroid-use-in-an-adolescent
#5
Jana Lichtenfeld, Barbara J Deal, Susan Crawford
Anabolic androgenic steroids are synthetic derivatives of testosterone that promote the growth of skeletal muscles and have many recognised cardiovascular effects. We report the clinical presentation and pathological findings of an adolescent male whose sudden cardiac arrest following ventricular fibrillation was attributed to anabolic androgenic steroid use. The age of our patient reflects the usage of anabolic androgenic steroids among younger athletes and highlights the need for increased awareness among practitioners...
June 2016: Cardiology in the Young
https://www.readbyqxmd.com/read/26957403/fontan-conversion-literature-review-and-lessons-learned-over-20-years
#6
Constantine Mavroudis, Barbara J Deal
Early survival after the Fontan operation has improved significantly leading to a lifetime of Fontan circulation for patients. There is a natural progression of pulmonary artery pressure during the human lifetime that is easily tolerated in two-ventricle physiology but is deleterious for single-ventricle physiology. Obstructions in the venous to pulmonary artery pathway and pulmonary venous return or ventricular outflow, atrioventricular valve dysfunction (regurgitation), pulmonary arteriovenous malformations, venous thrombosis, and the development of atrial arrhythmias can lead to reduced functional status...
March 2016: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/26955298/improving-medical-graduates-training-in-palliative-care-advancing-education-and-practice
#7
REVIEW
Barbara A Head, Tara J Schapmire, Lori Earnshaw, John Chenault, Mark Pfeifer, Susan Sawning, Monica A Shaw
The needs of an aging population and advancements in the treatment of both chronic and life-threatening diseases have resulted in increased demand for quality palliative care. The doctors of the future will need to be well prepared to provide expert symptom management and address the holistic needs (physical, psychosocial, and spiritual) of patients dealing with serious illness and the end of life. Such preparation begins with general medical education. It has been recommended that teaching and clinical experiences in palliative care be integrated throughout the medical school curriculum, yet such education has not become the norm in medical schools across the world...
2016: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/26691958/utilizing-in-house-resources-to-correct-sample-mixups-in-a-medium-throughput-biorepository-a-case-study
#8
Timothy J Geddes, Billie E Ketelsen, Samreen Ahmed, Barbara L Pruetz, Laura E Fortier
Given the high demands on a multidisciplinary approach to sample collection, and despite the rigorous quality assurance and quality control measures designed to minimize sample misidentification in our state of the art biorepository, the potential for error is still a concern. Measures to deal with potential uncertainties are a necessary part of every successful biobanking operation. The Beaumont BioBank and associated Core Molecular Laboratory have developed procedures to address these rare incidents. Here we present a case study of occurrences in the Beaumont BioBank in which the identity of samples was uncertain and a resolution workflow was implemented to quickly remove the ambiguity...
February 2016: Biopreservation and Biobanking
https://www.readbyqxmd.com/read/26647970/a-comprehensive-assessment-of-somatic-mutation-detection-in-cancer-using-whole-genome-sequencing
#9
COMPARATIVE STUDY
Tyler S Alioto, Ivo Buchhalter, Sophia Derdak, Barbara Hutter, Matthew D Eldridge, Eivind Hovig, Lawrence E Heisler, Timothy A Beck, Jared T Simpson, Laurie Tonon, Anne-Sophie Sertier, Ann-Marie Patch, Natalie Jäger, Philip Ginsbach, Ruben Drews, Nagarajan Paramasivam, Rolf Kabbe, Sasithorn Chotewutmontri, Nicolle Diessl, Christopher Previti, Sabine Schmidt, Benedikt Brors, Lars Feuerbach, Michael Heinold, Susanne Gröbner, Andrey Korshunov, Patrick S Tarpey, Adam P Butler, Jonathan Hinton, David Jones, Andrew Menzies, Keiran Raine, Rebecca Shepherd, Lucy Stebbings, Jon W Teague, Paolo Ribeca, Francesc Castro Giner, Sergi Beltran, Emanuele Raineri, Marc Dabad, Simon C Heath, Marta Gut, Robert E Denroche, Nicholas J Harding, Takafumi N Yamaguchi, Akihiro Fujimoto, Hidewaki Nakagawa, Víctor Quesada, Rafael Valdés-Mas, Sigve Nakken, Daniel Vodák, Lawrence Bower, Andrew G Lynch, Charlotte L Anderson, Nicola Waddell, John V Pearson, Sean M Grimmond, Myron Peto, Paul Spellman, Minghui He, Cyriac Kandoth, Semin Lee, John Zhang, Louis Létourneau, Singer Ma, Sahil Seth, David Torrents, Liu Xi, David A Wheeler, Carlos López-Otín, Elías Campo, Peter J Campbell, Paul C Boutros, Xose S Puente, Daniela S Gerhard, Stefan M Pfister, John D McPherson, Thomas J Hudson, Matthias Schlesner, Peter Lichter, Roland Eils, David T W Jones, Ivo G Gut
As whole-genome sequencing for cancer genome analysis becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is required. Here using tumour-normal sample pairs from two different types of cancer, chronic lymphocytic leukaemia and medulloblastoma, we conduct a benchmarking exercise within the context of the International Cancer Genome Consortium. We compare sequencing methods, analysis pipelines and validation methods. We show that using PCR-free methods and increasing sequencing depth to ∼ 100 × shows benefits, as long as the tumour:control coverage ratio remains balanced...
December 9, 2015: Nature Communications
https://www.readbyqxmd.com/read/26602004/intermediate-term-outcome-of-140-consecutive-fontan-conversions-with-arrhythmia-operations
#10
Barbara J Deal, John M Costello, Gregory Webster, Sabrina Tsao, Carl L Backer, Constantine Mavroudis
BACKGROUND: Atrial arrhythmias and progressive circulatory failure frequently develop in patients with a Fontan circulation. Improvement of flow dynamics and revision of the arrhythmia substrate may improve outcomes in selected patients. We sought to determine intermediate-term outcomes after Fontan conversion with arrhythmia operations and identify characteristics associated with decreased transplant-free survival. METHODS: The first 140 Fontan conversions with arrhythmia operations at a single institution were analyzed for predictors of cardiac death or transplant and incidence of arrhythmia recurrence...
February 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/26551351/capuchin-monkeys-cebus-apella-modulate-their-use-of-an-uncertainty-response-depending-on-risk
#11
Michael J Beran, Bonnie M Perdue, Barbara A Church, J David Smith
Metacognition refers to thinking about thinking, and there has been a great deal of interest in how this ability manifests across primates. Based on much of the work to date, a tentative division has been drawn with New World monkeys on 1 side and Old World monkeys and apes on the other. Specifically, Old World monkeys, apes, and humans often show patterns reflecting metacognition, but New World monkeys typically do not, or show less convincing behavioral patterns. However, recent data suggest that this difference may relate to other aspects of some experimental tasks...
January 2016: Journal of Experimental Psychology. Animal Learning and Cognition
https://www.readbyqxmd.com/read/26478232/can-patients-with-congenitally-corrected-transposition-of-the-great-arteries-live-better-electrically
#12
EDITORIAL
Barbara J Deal
No abstract text is available yet for this article.
January 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/26467864/growth-and-obesity-among-older-single-ventricle-patients-presenting-for-fontan-conversion
#13
Lindsay R Freud, Gregory Webster, John M Costello, Sabrina Tsao, Karen Rychlik, Carl L Backer, Barbara J Deal
INTRODUCTION: Long-term growth outcomes and the prevalence of obesity among older single ventricle (SV) patients have not been well characterized. We investigated these parameters, as well as the impact of obesity on survival, in an older cohort of SV patients presenting for Fontan conversion. METHODS: We analyzed preoperative height, weight, and body mass index (BMI) of patients who underwent Fontan conversion. Overweight and obese were defined as BMI ≥85 percentile and ≥95 percentile for patients <20 years and BMI 25 to 30 kg/m(2) and ≥30 kg/m(2) for patients ≥20 years, respectively...
October 2015: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/26409259/2015-acc-aha-hrs-guideline-for-the-management-of-adult-patients-with-supraventricular-tachycardia-a-report-of-the-american-college-of-cardiology-american-heart-association-task-force-on-clinical-practice-guidelines-and-the-heart-rhythm-society
#14
Richard L Page, José A Joglar, Mary A Caldwell, Hugh Calkins, Jamie B Conti, Barbara J Deal, N A Mark Estes, Michael E Field, Zachary D Goldberger, Stephen C Hammill, Julia H Indik, Bruce D Lindsay, Brian Olshansky, Andrea M Russo, Win-Kuang Shen, Cynthia M Tracy, Sana M Al-Khatib
No abstract text is available yet for this article.
April 5, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/26409258/2015-acc-aha-hrs-guideline-for-the-management-of-adult-patients-with-supraventricular-tachycardia-executive-summary-a-report-of-the-american-college-of-cardiology-american-heart-association-task-force-on-clinical-practice-guidelines-and-the-heart-rhythm-society
#15
Richard L Page, José A Joglar, Mary A Caldwell, Hugh Calkins, Jamie B Conti, Barbara J Deal, N A Mark Estes, Michael E Field, Zachary D Goldberger, Stephen C Hammill, Julia H Indik, Bruce D Lindsay, Brian Olshansky, Andrea M Russo, Win-Kuang Shen, Cynthia M Tracy, Sana M Al-Khatib
No abstract text is available yet for this article.
April 5, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/26409100/2015-acc-aha-hrs-guideline-for-the-management-of-adult-patients-with-supraventricular-tachycardia-a-report-of-the-american-college-of-cardiology-american-heart-association-task-force-on-clinical-practice-guidelines-and-the-heart-rhythm-society
#16
Richard L Page, José A Joglar, Mary A Caldwell, Hugh Calkins, Jamie B Conti, Barbara J Deal, N A Mark Estes Iii, Michael E Field, Zachary D Goldberger, Stephen C Hammill, Julia H Indik, Bruce D Lindsay, Brian Olshansky, Andrea M Russo, Win-Kuang Shen, Cynthia M Tracy, Sana M Al-Khatib
No abstract text is available yet for this article.
April 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/26409097/2015-acc-aha-hrs-guideline-for-the-management-of-adult-patients-with-supraventricular-tachycardia-executive-summary-a-report-of-the-american-college-of-cardiology-american-heart-association-task-force-on-clinical-practice-guidelines-and-the-heart-rhythm-society
#17
Richard L Page, José A Joglar, Mary A Caldwell, Hugh Calkins, Jamie B Conti, Barbara J Deal, N A Mark Estes Iii, Michael E Field, Zachary D Goldberger, Stephen C Hammill, Julia H Indik, Bruce D Lindsay, Brian Olshansky, Andrea M Russo, Win-Kuang Shen, Cynthia M Tracy, Sana M Al-Khatib
No abstract text is available yet for this article.
April 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/26399663/2015-acc-aha-hrs-guideline-for-the-management-of-adult-patients-with-supraventricular-tachycardia-a-report-of-the-american-college-of-cardiology-american-heart-association-task-force-on-clinical-practice-guidelines-and-the-heart-rhythm-society
#18
Richard L Page, José A Joglar, Mary A Caldwell, Hugh Calkins, Jamie B Conti, Barbara J Deal, N A Mark Estes, Michael E Field, Zachary D Goldberger, Stephen C Hammill, Julia H Indik, Bruce D Lindsay, Brian Olshansky, Andrea M Russo, Win-Kuang Shen, Cynthia M Tracy, Sana M Al-Khatib
No abstract text is available yet for this article.
April 5, 2016: Circulation
https://www.readbyqxmd.com/read/26399662/2015-acc-aha-hrs-guideline-for-the-management-of-adult-patients-with-supraventricular-tachycardia-executive-summary-a-report-of-the-american-college-of-cardiology-american-heart-association-task-force-on-clinical-practice-guidelines-and-the-heart-rhythm-society
#19
Richard L Page, José A Joglar, Mary A Caldwell, Hugh Calkins, Jamie B Conti, Barbara J Deal, N A Mark Estes, Michael E Field, Zachary D Goldberger, Stephen C Hammill, Julia H Indik, Bruce D Lindsay, Brian Olshansky, Andrea M Russo, Win-Kuang Shen, Cynthia M Tracy, Sana M Al-Khatib
No abstract text is available yet for this article.
April 5, 2016: Circulation
https://www.readbyqxmd.com/read/26363026/low-turnover-drug-molecules-a-current-challenge-for-drug-metabolism-scientists
#20
REVIEW
J Matthew Hutzler, Barbara J Ring, Shelby R Anderson
In vitro assays using liver subcellular fractions or suspended hepatocytes for characterizing the metabolism of drug candidates play an integral role in the optimization strategy employed by medicinal chemists. However, conventional in vitro assays have limitations in their ability to predict clearance and generate metabolites for low-turnover (slowly metabolized) drug molecules. Due to a rapid loss in the activity of the drug-metabolizing enzymes, in vitro incubations are typically performed for a maximum of 1 hour with liver microsomes to 4 hours with suspended hepatocytes...
December 2015: Drug Metabolism and Disposition: the Biological Fate of Chemicals
keyword
keyword
103259
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"