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https://www.readbyqxmd.com/read/28441790/eradicating-breast-cancer-longevity-impact-on-kuwaiti-women
#1
Muhammad Ali Al Ramadhan
Objective: To explore salient trends in incidence and mortality from breast cancer among Kuwaiti females and to quantify the number of years that could be saved if breast cancer deaths were eliminated. Methods: Appling life table technique, the paper constructs a bridged, multiple decrement and cancer-elimination life tables for Kuwaiti females. Data sources include Kuwait Cancer Control Center Registry along with vital statistics on mortality by age groups, nationality, and causes of death according to ICD-10 revision...
March 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28433923/uhplc-q-orbitrap-hrms-based-global-metabolomics-reveal-metabolome-modifications-in-plasma-of-young-women-after-cranberry-juice-consumption
#2
Haiyan Liu, Timothy J Garrett, Zhihua Su, Christina Khoo, Liwei Gu
Plasma metabolome in young women following cranberry juice consumption were investigated using a global UHPLC-Q-Orbitrap-HRMS approach. Seventeen female college students, between 21 and 29 years old, were given either cranberry juice or apple juice for three days using a cross-over design. Plasma samples were collected before and after juice consumption. Plasma metabolomes were analyzed using UHPLC-Q-Orbitrap-HRMS followed by orthogonal partial least squares-discriminant analyses (OPLS-DA). S-plot was used to identify discriminant metabolites...
April 7, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28431510/delayed-response-to-cold-stress-is-characterized-by-successive-metabolic-shifts-culminating-in-apple-fruit-peel-necrosis
#3
Nigel E Gapper, Maarten L A T M Hertog, Jinwook Lee, David A Buchanan, Rachel S Leisso, Zhangjun Fei, Guiqin Qu, James J Giovannoni, Jason W Johnston, Robert J Schaffer, Bart M Nicolaï, James P Mattheis, Christopher B Watkins, David R Rudell
BACKGROUND: Superficial scald is a physiological disorder of apple fruit characterized by sunken, necrotic lesions appearing after prolonged cold storage, although initial injury occurs much earlier in the storage period. To determine the degree to which the transition to cell death is an active process and specific metabolism involved, untargeted metabolic and transcriptomic profiling was used to follow metabolism of peel tissue over 180 d of cold storage. RESULTS: The metabolome and transcriptome of peel destined to develop scald began to diverge from peel where scald was controlled using antioxidant (diphenylamine; DPA) or rendered insensitive to ethylene using 1-methylcyclopropene (1-MCP) beginning between 30 and 60 days of storage...
April 21, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/28419685/scaffolds-for-epithelial-tissue-engineering-customized-in-elastomeric-molds
#4
Mohamed-Nur Abdallah, Sara Abdollahi, Marco Laurenti, Dongdong Fang, Simon D Tran, Marta Cerruti, Faleh Tamimi
Restoration of soft tissue defects remains a challenge for surgical reconstruction. In this study, we introduce a new approach to fabricate poly(d,l-lactic acid) (PDLLA) scaffolds with anatomical shapes customized to regenerate three-dimensional soft tissue defects. Highly concentrated polymer/salt mixtures were molded in flexible polyether molds. Microcomputed tomography showed that with this approach it was possible to produce scaffolds with clinically acceptable volume ratio maintenance (>90%). Moreover, this technique allowed us to customize the average pore size and pore interconnectivity of the scaffolds by using variations of salt particle size...
April 18, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28414437/phenolic-content-and-antioxidant-activity-during-the-development-of-brookfield-and-mishima-apples
#5
Mayara C Stanger, Cristiano A Steffens, Cristina Soethe, Marcelo A Moreira, Cassandro V T do Amarante
The aim of this study was to characterize the changes in the contents of total (TPC) and individual (IPC) phenolic compounds, the total antioxidant activity (TAA) in the peel and pulp, and total anthocyanins (TAN) in the peel during the development of the fruits of 'Brookfield' and 'Mishima' apple trees. 'Brookfield' apples were harvested from the 49th to the 138th days after full bloom (DAFB) and 'Mishima' apples from the 45th to the 172th DAFB. In the pulp, the IPC, TPC, and TAA rapidly reduced at 75 and 79 DAFB for the 'Brookfield' and 'Mishima' apples, respectively, and then remained constant until commercial maturity...
April 24, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28412068/vitreous-amyloidosis-ocular-systemic-and-genetic-insights
#6
Pradeep Venkatesh, Harathy Selvan, Sundararajan Baskar Singh, Divya Gupta, Seema Kashyap, Shreyas Temkar, Varun Gogia, Koushik Tripathy, Rohan Chawla, Rajpal Vohra
PURPOSE: To report the unique clinical and surgical characteristics encountered in eyes with vitreous amyloidosis. Systemic evaluation and visual outcome after vitrectomy are discussed. A novel mutation in the transthyretin gene (TTR) in Indian patients with familial amyloid polyneuropathy (FAP) is described. DESIGN: Retrospective, observational study. PARTICIPANTS: Ten eyes of 5 patients from 2 pedigrees with a diagnosis of vitreous amyloidosis...
April 12, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28405813/estimation-of-dietary-total-antioxidant-capacity-of-korean-adults
#7
Shinyoung Jun, Ock K Chun, Hyojee Joung
PURPOSE: Dietary total antioxidant capacity (TAC) has been reported to be inversely associated with the risk of chronic diseases. However, little is known about dietary TAC among the Korean population. Therefore, we aimed to estimate the dietary TAC of Korean adults and to document the major food sources. METHODS: We studied 33,581 Korean adults aged ≥19 years who participated in the Korea National Health and Nutrition Examination Survey 2007-2012. Dietary TAC was estimated from 1-day 24-h dietary recall data using a TAC database comprising antioxidant capacities of 42 dietary antioxidants, developed for common Korean foods...
April 12, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28387952/work-productivity-in-rhinitis-using-cell-phones-the-mask-pilot-study
#8
J Bousquet, M Bewick, S Arnavielhe, E Mathieu-Dupas, R Murray, A Bedbrook, D P Caimmi, O VandenPlas, P W Hellings, C Bachert, J M Anto, K C Bergmann, C Bindslev-Jensen, S Bosnic-Anticevitch, J Bouchard, G W Canonica, N H Chavannes, A A Cruz, R Dahl, P Demoly, G De Vries, P Devillier, A Fink-Wagner, W J Fokkens, J Fonseca, N Guldemond, T Haahtela, B Hellqvist-Dahl, J Just, T Keil, L Klimek, M L Kowalski, P Kuna, V Kvedariene, D Laune, D Larenas-Linnemann, J Mullol, A M Pereira, P Carreiro-Martins, E Melén, M Morais-Almeida, L Nogueira-Silva, R E O'Hehir, N G Papadopoulos, G Passalacqua, F Portejoie, D Price, D Ryan, B Samolinski, A Sheikh, F E R Simons, O Spranger, A Todo Bom, P V Tomazic, M Triggiani, A Valero, E Valovirta, A Valiulis, M van Eerd, M Wickman, I Young, T Zuberbier
Allergic rhinitis often impairs social life and performance. The aim of this cross-sectional study was to assess the impact of uncontrolled rhinitis assessed by visual analogue score VAS on work productivity using cell phone data collection. A mobile phone app Allergy Diary, Android and Apple stores collects daily visual analogue scales VAS data for overall allergic symptoms VAS-global measured, nasal VAS-nasal, ocular VAS-ocular, asthma symptoms VAS-asthma and work VAS-work. A combined nasal-ocular score is calculated...
April 7, 2017: Allergy
https://www.readbyqxmd.com/read/28383795/fabrication-and-characterization-of-electrospun-polycaprolactone-and-gelatin-composite-cuffs-for-tissue-engineered-blood-vessels
#9
Hannah A Strobel, Elizabeth L Calamari, Alexander Beliveau, Anjana Jain, Marsha W Rolle
Sewing cuffs incorporated within tissue-engineered blood vessels (TEBVs) enable graft anastomosis in vivo, and secure TEBVs to bioreactors in vitro. Alternative approaches to cuff design are required to achieve cuff integration with scaffold-free TEBVs during tissue maturation. To create porous materials that promote tissue integration, we used electrospinning to fabricate cuffs from polycaprolactone (PCL), PCL blended with gelatin, and PCL coated with gelatin, and evaluated cuff mechanical properties, porosity, and cellular attachment and infiltration...
April 6, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28378269/traps-and-baits-for-luring-grapholita-molesta-busck-adults-in-mating-disruption-treated-apple-orchards
#10
A C Padilha, C J Arioli, M I C Boff, J M Rosa, M Botton
Grapholita molesta (Busck) is one of the main pests in apple crops in Brazil, where it is controlled by mating disruption (MD) with the use of the synthetic sex pheromone. However, sex-pheromone-based monitoring is not effective in MD-treated areas and may result in losses in production. This work has defined a trap model and a bait for luring G. molesta adults in MD apple orchards. The experiments were conducted in commercial apple orchards located in São Joaquim, SC, Brazil. Three trap models-McPhail, Pot, and Ajar-and three baits-grape juice (25%) (GJ), sugarcane molasses (25%) (SM), and a solution containing brown sugar (8...
April 4, 2017: Neotropical Entomology
https://www.readbyqxmd.com/read/28376257/the-stiffness-of-a-crosslinked-hyaluronan-hydrogel-affects-its-chondro-induction-activity-on-hadscs
#11
Benjamin Teong, Shun-Cheng Wu, Chien-Mei Chang, Jhen-Wei Chen, Hui-Ting Chen, Chung-Hwan Chen, Je-Ken Chang, Mei-Ling Ho
Matrix stiffness plays an important role in stem cell differentiation. This study reports the synthesis of methacrylated hyaluronan (MeHA) with different degrees of methacrylation, ranging from 15 to 140% per disaccharide unit, which corresponds to a matrix stiffness ranging from 1.5 to 8 KPa. The swelling ratio was inversely proportional to the matrix stiffness, but the water content remained constant at >97% of the hydrogel mass. A fibril-like surface morphology and larger pore size were observed in lyophilized MeHA hydrogel with a lower stiffness...
April 4, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28364359/mhealth-app-for-ios-to-help-in-diagnostic-decision-in-ophthalmology-to-primary-care-physicians
#12
Marta Manovel López, Miguel Maldonado López, Isabel de la Torre Díez, José Carlos Pastor Jimeno, Miguel López-Coronado
Decision support systems (DSS) are increasingly demanded due that diagnosis is one of the main activities that physicians accomplish every day. This fact seems critical when primary care physicians deal with uncommon problems belonging to specialized areas. The main objective of this paper is the development and user evaluation of a mobile DSS for iOS named OphthalDSS. This app has as purpose helping in anterior segment ocular diseases' diagnosis, besides offering educative content about ophthalmic diseases to users...
May 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28359205/quality-stability-and-sensory-attributes-of-apple-juice-processed-by-thermosonication-pulsed-electric-field-and-thermal-processing
#13
Alifdalino Sulaiman, Mohammed Farid, Filipa Vm Silva
Worldwide, apple juice is the second most popular juice, after orange juice. It is susceptible to enzymatic browning spoilage by polyphenoloxidase, an endogenous enzyme. In this study, Royal Gala apple juice was treated by thermosonication (TS: 1.3 W/mL, 58 ℃, 10 min), pulsed electric field (PEF: 24.8 kV/cm, 60 pulses, 169 µs treatment time, 53.8 ℃) and heat (75 ℃, 20 min) and stored at 3.0 ℃ and 20.0 ℃ for 30 days. A sensory analysis was carried out after processing. The polyphenoloxidase activity, antioxidant activity and total color difference of the apple juice were determined before and after processing and during storage...
April 2017: Food Science and Technology International, Ciencia y Tecnología de Los Alimentos Internacional
https://www.readbyqxmd.com/read/28351643/chemically-modified-halloysite-nanotubes-as-a-solid-phase-microextraction-coating
#14
Mohammad Saraji, Mohammad Taghi Jafari, Mehdi Mossaddegh
Halloysite nanotubes were modified in three simple steps including etching, hydroxylation and amino grafting. The sol-gel technique was used for the chemical bonding of the modified halloysite nanotubes (MHNTs) to fused-silica support. The MHNTs, as a novel adsorbent was applied as a SPME coating. Diazinon, parathion and fenthion were selected as the model compounds to study the extraction efficiency of the coating. Gas chromatography-corona discharge ion mobility spectrometry was applied for the analysis of the extracted analytes...
April 29, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28349309/dissipation-of-chlorantraniliprole-chlorpyrifos-methyl-and-indoxacarb-insecticides-used-to-control-codling-moth-cydia-pomonella-l-and-leafrollers-tortricidae-in-apples-for-production-of-baby-food
#15
Ewa Szpyrka, Aneta Matyaszek, Magdalena Słowik-Borowiec
Dissipations of three insecticides: chlorantraniliprole, chlorpyrifos-methyl and indoxacarb in apples were studied following their foliar application on apples intended for production of baby food. The apples were sprayed with formulations for control of codling moth (Cydia Pomonella L.) and leafrollers (Tortricidae). Six experiments were conducted; each insecticide was applied individually on dessert apples. A validated gas chromatography-based method with simultaneous electron capture and nitrogen-phosphorus detection (GC-ECD/NPD) was used for the residue analysis...
March 27, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28344141/single-high-sensitivity-cardiac-troponin-i-to-rule-out-acute-myocardial-infarction
#16
Yader Sandoval, Stephen W Smith, Sara A Love, Anne Sexter, Karen Schulz, Fred S Apple
PURPOSE: Examine the performance of single high-sensitivity cardiac troponin I (hs-cTnI) measurement strategies to rule-out acute myocardial infarction. METHODS: Prospective, observational study of consecutive patients presenting to the emergency department (n=1,631) in whom cTnI measurements where obtained using an investigational hs-cTnI assay. Negative predictive value (NPV) and sensitivity for the a) diagnosis of acute myocardial infarction, type 1 myocardial infarction, and type 2 myocardial infarction and b) safety outcome of acute myocardial infarction or cardiac death at 30 days using hs-cTnI less than the limit of detection (LoD) (<1...
March 23, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28341432/development-validation-and-evaluation-of-an-analytical-method-for-the-determination-of-monomeric-and-oligomeric-procyanidins-in-apple-extracts
#17
Wendy J Hollands, Stefan Voorspoels, Griet Jacobs, Kjersti Aaby, Ane Meisland, Rocio Garcia-Villalba, Francisco Tomas-Barberan, Mariusz K Piskula, Deborah Mawson, Irena Vovk, Paul W Needs, Paul A Kroon
There is a lack of data for individual oligomeric procyanidins in apples and apple extracts. Our aim was to develop, validate and evaluate an analytical method for the separation, identification and quantification of monomeric and oligomeric flavanols in apple extracts. To achieve this, we prepared two types of flavanol extracts from freeze-dried apples; one was an epicatechin-rich extract containing ∼30% (w/w) monomeric (-)-epicatechin which also contained oligomeric procyanidins (Extract A), the second was an oligomeric procyanidin-rich extract depleted of epicatechin (Extract B)...
April 28, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28338764/fruit-and-vegetable-intake-and-the-risk-of-cardiovascular-disease-total-cancer-and-all-cause-mortality-a-systematic-review-and-dose-response-meta-analysis-of-prospective-studies
#18
Dagfinn Aune, Edward Giovannucci, Paolo Boffetta, Lars T Fadnes, NaNa Keum, Teresa Norat, Darren C Greenwood, Elio Riboli, Lars J Vatten, Serena Tonstad
Background: Questions remain about the strength and shape of the dose-response relationship between fruit and vegetable intake and risk of cardiovascular disease, cancer and mortality, and the effects of specific types of fruit and vegetables. We conducted a systematic review and meta-analysis to clarify these associations. Methods: PubMed and Embase were searched up to 29 September 2016. Prospective studies of fruit and vegetable intake and cardiovascular disease, total cancer and all-cause mortality were included...
February 22, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28330279/immobilization-of%C3%A2-bacillus-amyloliquefaciens-sp1-and-its-alkaline-protease-in-various-matrices-for-effective-hydrolysis-of-casein
#19
Shiwani Guleria, Abhishek Walia, Anjali Chauhan, C K Shirkot
An extracellular alkaline protease producing B. amyloliquefaciens SP1 was isolated from apple rhizosphere having multifarious plant growth-promoting activities. B. amyloliquefaciens SP1 protease was immobilized using various concentrations of calcium alginate, agar and polyacrylamide to determine the optimum concentration for formation of the beads. Enzyme activity before immobilization (at 60 °C, pH 8.0 for 5 min) was 3580 µg/ml/min. The results of immobilization with various matrices revealed that 3 % calcium alginate (2829...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28328390/the-efficacy-of-telemedicine-supported-discharge-within-an-in-home-model-of-care
#20
Edwin P Greenup, Melissa McCusker, Boyd A Potts, Andrew Bryett
OBJECTIVE: To determine if mobile videoconferencing technology can facilitate the discharge of low-acuity patients receiving in-home care without compromising short-term health outcomes. METHODS: A 6-month trial commenced in July 2015 with 345 patients considered unsuited to Criteria Led Discharge (CLD) receiving in-home care included as participants. Nurses providing clinical support to patients in their homes were supplied with a tablet computer (Apple iPad) with Internet connectivity (Telstra 4G Network) and videoconferencing software (Cisco Jabber for Telepresence)...
February 22, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
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