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https://www.readbyqxmd.com/read/28238909/apple-polysaccharide-inhibits-microbial-dysbiosis-and-chronic-inflammation-and-modulates-gut-permeability-in-hfd-fed-rats
#1
Sheng Wang, Qian Li, Yue Zang, Yang Zhao, Nan Liu, Yifei Wang, Xiaotao Xu, Li Liu, Qibing Mei
The saying "An apple a day keeps the doctor away" has been known for over 150 years, and numerous studies have shown that apple consumption is closely associated with reduced risks of chronic diseases. It has been well accepted that dysbiosis is the reflection of various chronic diseases. Therefore, this study investigates the effects of apple polysaccharides (AP) on gut dysbiosis. High-fat diet (HFD) fed rats were treated for 14 weeks with AP. The microbiota composition, microbiota-generated short chain fatty acids (SCFAs), gut permeability and chronic inflammation were analyzed...
February 23, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28237958/study-protocol-for-a-pragmatic-randomised-controlled-trial-evaluating-efficacy-of-a-smoking-cessation-e-tabac-info-service-ee-tis-trial
#2
L Cambon, P Bergman, Al Le Faou, I Vincent, B Le Maitre, A Pasquereau, P Arwidson, D Thomas, F Alla
INTRODUCTION: A French national smoking cessation service, Tabac Info Service, has been developed to provide an adapted quitline and a web and mobile application involving personalised contacts (eg, questionnaires, advice, activities, messages) to support smoking cessation. This paper presents the study protocol of the evaluation of the application (e-intervention Tabac Info Service (e-TIS)). The primary objective is to assess the efficacy of e-TIS. The secondary objectives are to (1) describe efficacy variations with regard to users' characteristics, (2) analyse mechanisms and contextual conditions of e-TIS efficacy...
February 24, 2017: BMJ Open
https://www.readbyqxmd.com/read/28221974/evaluation-of-a-surface-sampling-method-for-recovery-of-human-noroviruses-prior-to-detection-using-reverse-transcription-quantitative-pcr
#3
Grace Tung-Thompson, Blanca I Escudero-Abarca, Janie Outlaw, Arnaud Ganee, Sylvanie Cassard, Claude Mabilat, Lee-Ann Jaykus
Human noroviruses are the most common cause of acute viral gastroenteritis, and the environmental persistence of these viruses contributes to their transmissibility. Environmental sampling is thus an important tool for investigating norovirus outbreaks and for assessing the effectiveness of cleaning and decontamination regimens. The purpose of this study was to evaluate a sampling material (wipes) for their efficacy at recovering human norovirus from hard surfaces and foods. Dilutions of a human norovirus GII...
February 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28205206/apples-and-oranges-four-definitions-of-multiple-chronic-conditions-and-their-relationship-to-30-day-hospital-readmission
#4
Melissa Dattalo, Eva DuGoff, Katie Ronk, Korey Kennelty, Andrea Gilmore-Bykovskyi, Amy J Kind
OBJECTIVES: To determine the extent of agreement between four commonly used definitions of multiple chronic conditions (MCCs) and compare each definition's ability to predict 30-day hospital readmissions. DESIGN: Retrospective cohort study. SETTING: National Medicare claims data. PARTICIPANTS: Random sample of Medicare beneficiaries discharged from the hospital from 2005 to 2009 (n = 710,609). MEASUREMENTS: Baseline chronic conditions were determined for each participant using four definitions of MCC...
February 15, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28196336/regression-of-atherosclerosis-with-apple-procyanidins-by-activating-the-atp-binding-cassette-subfamily-a-member-1-in-a-rabbit-model
#5
Liang Wang, Toshio Fumoto, Saeko Masumoto, Toshihiko Shoji, Tomisato Miura, Masato Naraoka, Naoya Matsuda, Tadaatsu Imaizumi, Hiroki Ohkuma
BACKGROUND AND AIMS: Apple polyphenol contains abundant procyanidins, which have been associated with an anti-atherosclerosis and cholesterol-lowering effect. The aim of this study was to investigate whether apple procyanidins (APCs) feature therapeutic efficacy in terms of regressing atherosclerosis and whether this efficacy is due to mechanisms other than a cholesterol-lowering effect. METHODS: After eight weeks on an atherogenic diet, rabbits were given a normal diet for another eight weeks to normalize the increased serum lipids level...
January 27, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28195398/preparation-of-magnetic-mesoporous-silica-composite-for-the-solid-phase-microextraction-of-diazinon-and-malathion-before-their-determination-by-high-performance-liquid-chromatography
#6
Alireza Bazmandegan-Shamili, Ali Mohammad Haji Shabani, Shayessteh Dadfarnia, Masoud Rohani Moghadam, Mahboubeh Saeidi
A novel magnetic mesoporous silica material was synthesized and used as the sorbent for the magnetic solid-phase microextraction of diazinon and malathion before their quantification by high-performance liquid chromatography with UV detection. The sorbent was synthesized by a surfactant-templated one-pot sol-gel procedure using SiO2 -coated Fe3 O4 as the magnetic support, cetyltrimethylammonium bromide as the template and tetraethyl orthosilicate as the silicon source. The characteristics of the prepared sorbent were investigated using FTIR spectroscopy, scanning electron microscopy, and X-ray diffraction...
February 13, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28194717/metal-chelate-immobilization-of-lipase-onto-polyethylenimine-coated-mcm-41-for-apple-flavor-synthesis
#7
Armin Sadighi, Seyed Farshad Motevalizadeh, Morteza Hosseini, Ali Ramazani, Lena Gorgannezhad, Hamid Nadri, Behnaz Deiham, Mohammad Reza Ganjali, Abbas Shafiee, Mohammad Ali Faramarzi, Mehdi Khoobi
An enzyme immobilized on a mesoporous silica nanoparticle can serve as a multiple catalyst for the synthesis of industrially useful chemicals. In this work, MCM-41 nanoparticles were coated with polyethylenimine (MCM-41@PEI) and further modified by chelation of divalent metal ions (M = Co(2+), Cu(2+), or Pd(2+)) to produce metal-chelated silica nanoparticles (MCM-41@PEI-M). Thermomyces lanuginosa lipase (TLL) was immobilized onto MCM-41, MCM-41@PEI, and MCM-41@PEI-M by physical adsorption. Maximum immobilization yield and efficiency of 75 ± 3...
February 13, 2017: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/28188976/influence-of-hypoxia-on-the-stemness-of-umbilical-cord-matrix-derived-mesenchymal-stem-cells-cultured-on-chitosan-films
#8
Takashi Taguchi, Jane Y Cho, Jijun Hao, Yvette S Nout-Lomas, Kyung-Sun Kang, Dominique J Griffon
Chitosan is attractive as a substrate for stem cell expansion because it improves stemness through formation of spheroids. Hypoxia has also been proposed as a strategy to enhance stemness and survival of stem cells after in vivo implantation. This study was therefore designed to evaluate the influence of hypoxia on chitosan-induced behavior of stem cells. Umbilical cord matrix-derived stem cells were cultured on chitosan film or standard plate under normoxia and hypoxia, for 3 and 7 days. Based on immunophenotyping, chitosan strongly suppresses the expression of CD90 and CD105 cell surface markers, changes partially reversed by combined exposure to hypoxia...
February 11, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28177724/dose-dependent-decrease-in-mortality-with-no-cognitive-or-muscle-function-improvements-due-to-dietary-egcg-supplementation-in-aged-mice
#9
Brandt D Pence, Tushar K Bhattacharya, Pul Park, Jennifer L Rytych, Jacob M Allen, Yi Sun, Robert H McCusker, Keith W Kelley, Rodney W Johnson, Justin S Rhodes, Jeffrey A Woods
We have previously shown that a diet containing epigallocatechin gallate (EGCG) and beta-alanine is not effective in improving either cognitive or muscle function in aged (18 month) mice (Gibbons et al. Behav Brain Res 2014, Pence et al. Appl Physiol Nutr Metab 2016). However, this diet reduced oxidative stress in the brain, and previous studies using longer-term interventions and other doses have documented beneficial effects in cognitive and muscle function, especially with EGCG. Here we hypothesized that a different dose of EGCG or longer feeding period would be more efficacious in improving cognition...
January 5, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28140510/improving-risk-assessment-of-color-additives-in-medical-device-polymers
#10
Vaishnavi Chandrasekar, Dustin W Janes, Christopher Forrey, David M Saylor, Akhil Bajaj, Timothy V Duncan, Jiwen Zheng, Kausar B Riaz Ahmed, Brendan J Casey
Many polymeric medical device materials contain color additives which could lead to adverse health effects. The potential health risk of color additives may be assessed by comparing the amount of color additive released over time to levels deemed to be safe based on available toxicity data. We propose a conservative model for exposure that requires only the diffusion coefficient of the additive in the polymer matrix, D, to be specified. The model is applied here using a model polymer (poly(ether-block-amide), PEBAX 2533) and color additive (quinizarin blue) system...
January 31, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28130877/mimicking-physiological-flow-conditions-to-study-alterations-of-bioactive-glass-surfaces-in-vitro
#11
Miriam Höner, Frederik Böke, Michael Weber, Horst Fischer
Bioactive glasses form a strong bond with surrounding tissue and slowly degrade when implanted in vivo, stimulating the host bone to regenerate itself. We investigated the behaviour of microstructured bioactive glass surfaces (13-93) in an SBF reactor, which mimics physiological flow conditions. The structures were developed to potentially influence cell-biological long term processes such as osteogenic differentiation. It is therefore important that the structures withstand a certain time in SBF or body fluids...
January 27, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28130836/optimized-performance-of-the-integrated-hepatic-cell-loaded-cryogel-based-bioreactor-with-intermittent-perfusion-of-acute-liver-failure-plasma
#12
Apeksha Damania, Anupam Kumar, Shiv K Sarin, Ashok Kumar
Acute liver failure (ALF) plasma has cytotoxic effects on the cell-loaded bioreactor in bioartificial liver support systems due to the presence of innumerable hepatotoxic compounds that adversely affect the morphology and functionality of the cells. We have designed a hybrid bioreactor that integrates a hepatic cell-loaded cryogel disc and an activated carbon cloth in one compact unit, with potential application as a bioartificial liver support. In this article, we assess the performance of this integrated hybrid cryogel-based bioreactor in a perfusion-based culture system and analyze its functionality and longevity in the presence of intermittent exposure to ALF plasma...
January 27, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28103422/vitamin-supplementation
#13
EDITORIAL
P B Persson, A B Persson
No abstract text is available yet for this article.
March 2017: Acta Physiologica
https://www.readbyqxmd.com/read/28101467/some-qualitative-and-rheological-properties-of-virgin-olive-oil-apple-vinegar-salad-dressing-stabilized-with-xanthan-gum
#14
Solmaz Abedinzadeh, Mohammadali Torbati, Sodeif Azadmard-Damirchi
Purpose: Lipid oxidation and rheological properties are the main qualitative parameters determined in food emulsions. Salad dressings are food emulsions important in our daily diet, but conventional salad dressings have high amounts of cholesterol and saturated fatty acids because of egg yolk in their formulations. There are many studies on the modification of salad dressing formulations to replace egg yolk and saturated fats. The present study describes new formulation of salad dressing with olive oil and apple vinegar to produce a functional food product...
December 2016: Advanced Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28031473/relative-efficacy-of-two-clades-of-aphelinus-mali-hymenoptera-aphelinidae-for-control-of-woolly-apple-aphid-hemiptera-aphididae-in-china
#15
Min Su, Xiumei Tan, Qinmin Yang, Hongxu Zhou, Fanghao Wan
Aphelinus mali (Haldeman) is an effective natural enemy used in China to control woolly apple aphid. Previous studies have found that populations of A. mali in China fall into two distinct genetic clades. We found that one of these, the Shandong clade, is more effective as a biological control agent than the Liaoning clade. The control ability of the Shandong clade of A. mali (a/Th = 2.447) was found to be stronger than that of the Liaoning clade (a/Th = 1.278); the search parameter (Q) and the mutual interference parameter (m) of the Shandong clade (0...
December 28, 2016: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28008718/binary-solvent-based-ionic-liquid-assisted-surfactant-enhanced-emulsification-microextraction-for-the-determination-of-four-fungicides-in-apple-juice-and-apple-vinegar
#16
Xiaochu Chen, Xu Zhang, Fengmao Liu, Fan Hou
A binary-solvent-based ionic-liquid-assisted surfactant-enhanced emulsification microextraction method was developed for the separation/preconcentration and determination of four fungicides (pyrimethanil, fludioxonil, cyprodynil, pyraclostrobin) in apple juice and apple vinegar. A nonchlorinated solvent amyl acetate, which has a lower density than water, was used as the extraction solvent, and an ionic liquid 1-hexyl-3-methylimidazolium hexafluorophosphate, which has a high density and low toxicity, was used as a secondary solvent mixed with the extraction solvent...
December 23, 2016: Journal of Separation Science
https://www.readbyqxmd.com/read/28002165/improving-prediction-of-postoperative-myocardial-infarction-with-high-sensitivity-cardiac-troponin-t-and-nt-probnp
#17
Michael Kopec, Andreas Duma, Mohammad A Helwani, Jamie Brown, Frank Brown, Brian F Gage, David W Gibson, J Philip Miller, Eric Novak, Allan S Jaffe, Fred S Apple, Mitchell G Scott, Peter Nagele
BACKGROUND: This study sought to determine whether preoperatively measured high-sensitivity cardiac troponin T (hs-cTnT) and N-terminal pro-brain natriuretic peptide (NT-proBNP) improve cardiac risk prediction in patients undergoing major noncardiac surgery compared with the standard risk indices. METHODS: In this ancillary study to the Vitamins in Nitrous Oxide trial, patients were included who had preoperative hs-cTnT and NT-proBNP measured (n = 572). Study outcome was the incidence of postoperative myocardial infarction (MI) within the first 3 postoperative days...
February 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27987978/immobilization-of-pectinase-onto-chitosan-magnetic-nanoparticles-by-macromolecular-cross-linker
#18
Uttam V Sojitra, Shamraja S Nadar, Virendra K Rathod
Pectinase was immobilized onto chitosan magnetic nanoparticles (CMNPs) by dextran polyaldehyde as a macromolecular cross-linking agent. The parameters like cross-linking concentration, time and CMNPs to enzyme ratio were optimized. Further, prepared magnetic pectinase nanobiocatalyst was characterized by FT-IR and XRD. The thermal kinetic studies for immobilized pectinase showed two folds improved thermal stability in the range of 55-75°C as compared to free form. The Vmax and Km values of immobilized pectinase were found to be nearly equal to native form which indicated that conformational flexibility of pectinase was retained even after immobilization...
February 10, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/27979240/preharvest-interval-periods-and-their-relation-to-fruit-growth-stages-and-pesticide-formulations
#19
Claudio Alister, Manuel Araya, Kevin Becerra, Jorge Saavedra, Marcelo Kogan
The aim of this study was to evaluate the effect of pesticide formulations and fruit growth stages on the Pre-harvest Interval Period (PHI). Results showed that pesticide formulations did not affect the initial deposit and dissipation rate. However, the fruit growth stage at the application time showed a significant effect on the above-mentioned parameters. Fruit diameter increases in one millimeter pesticide dissipation rates were reduced in -0.033mgkg(-1)day(-1) (R(2)=0.87; p<0.001) for grapes and -0.014mgkg(-1)day(-1) (R(2)=0...
April 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27925384/co-micellized-pluronic-mixture-with-thermo-sensitivity-and-residence-stability-as-an-injectable-tissue-adhesion-barrier-hydrogel
#20
Se Heang Oh, Jun Goo Kang, Jin Ho Lee
Although the tissue adhesion which leads to various complications frequently occurs after surgery, the development of an ideal tissue adhesion barrier is still a challenge. In this study, a thermo-sensitive hydrogel, which can fulfill the essential requirements of tissue adhesion barrier (that is, ease of handling for surgeon, flowing down prevention after application, stable residence on the injury during wound healing, and no use of toxic additives), was developed using biocompatible polyethylene glycol-polypropylene glycol copolymers (Pluronic F127/F68/P123 mixture)...
December 7, 2016: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
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