keyword
https://read.qxmd.com/read/38537259/towards-the-establishment-of-national-diagnostic-reference-levels-for-abdomen-kub-and-lumbar-spine-x-ray-examinations-in-sri-lanka-a-multi-centric-study
#21
JOURNAL ARTICLE
Sachith Welarathna, Sivakumar Velautham, Sivananthan Sarasanandarajah
Diagnostic reference levels (DRLs) and achievable doses (ADs) provide guidance to optimise radiation doses for patients undergoing medical imaging procedures. This multi-centre study aimed to compare institutional DRLs (IDRLs) across hospitals, propose ADs and multi-centric DRLs (MCDRLs) for four common x-ray examinations in Sri Lanka, and assess the potential for dose reduction. A prospective cross-sectional study of 894 adult patients referred for abdomen anteroposterior (AP), kidney-ureter-bladder (KUB) AP, lumbar spine AP, and lumbar spine lateral (LAT) x-ray examinations was conducted...
March 27, 2024: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://read.qxmd.com/read/38535767/evaluation-of-radiation-exposure-and-influential-factors-in-cone-beam-computed-tomography-cbct-of-the-head-and-abdomen-during-interventional-procedures
#22
JOURNAL ARTICLE
Mingming Li, Weiwei Qu, Dong Zhang, Binyan Zhong, Zhi Li, Zhengyu Jiang, Guanyin Ni, Caifang Ni
Cone-beam computed tomography (CBCT) is a widely used imaging technique in interventional radiology. Although CBCT offers great advantages in terms of improving comprehension of complex angioarchitectures and guiding therapeutic decisions, its additional degree of radiation exposure has also aroused considerable concern. In this study, we aimed to assess radiation exposure and its influential factors in patients undergoing CBCT scans of the head and abdomen during interventional procedures. A total of 752 patients were included in this retrospective study...
February 26, 2024: Tomography: a Journal for Imaging Research
https://read.qxmd.com/read/38535513/suprapubic-and-transurethral-bladder-access-for-voiding-cystourethrography-in-pediatric-male-patients
#23
JOURNAL ARTICLE
Wiebke Schlötelburg, Clemens Benoit, Mandy Kasper, Bernhard Petritsch, Andreas Max Weng, Thorsten Alexander Bley, Simon Veldhoen
PURPOSE: To compare suprapubic access (SPA) and transurethral catheterization (TUC) in voiding cystourethrogram (VCUG). METHODS: Retrospective single-center evaluation of 311 VCUG performed in male patients under 12 years of age. Two study groups were built based on the bladder access method. TUC was performed in 213 patients, whereas 98 received SPA. The groups were compared regarding the procedural switch rate, the complication rate, radiation parameters, the amount of contrast media applied and the examination quality...
March 13, 2024: Pediatric Reports
https://read.qxmd.com/read/38535372/development-and-metabolomic-profiles-of-bactrocera-dorsalis-diptera-tephritidae-larvae-exposed-to-phytosanitary-irradiation-dose-in-hypoxic-environment-using-di-spme-gc-ms
#24
JOURNAL ARTICLE
Changyao Shan, Baishu Li, Li Li, Qun Liu, Hang Zou, Tao Liu
X-ray irradiation and modified atmospheres (MAs) provide eco-friendly, chemical-free methods for pest management. Although a low-oxygen atmospheric treatment improves the performance of some irradiated insects, its influence on the irradiation of quarantine insects and its impacts on pest control efficacy have yet to be investigated. Based on bioassay results, this study employed direct immersion solid-phase microextraction (DI-SPME) combined with gas chromatography-mass spectrometry (GC-MS) to determine metabolic profiles of late third-instar B...
March 6, 2024: Insects
https://read.qxmd.com/read/38535228/five-new-species-of-gymnopilus-from-xizang-autonomous-region-of-china-and-surrounding-areas
#25
JOURNAL ARTICLE
Wen-Qiang Yang, Jia-Xin Li, Mao-Qiang He, Shi-Hui Wang, Xin-Yu Zhu, Dorji Phurbu, Jian-Min Yun, Rui-Lin Zhao
The species of Gymnopilus (Hymenogastraceae, Agricales) are commonly recognized as wood-decaying fungi. Certain members of this genus have been identified as psilocybin-producing mushrooms. Gymnopilus exhibits a diverse range and has a global distribution. In this study, a total of seventy-eight specimens were gathered from ten provinces in China. A comprehensive molecular phylogenetic analysis was conducted, employing gene sequences including ITS, nrLSU, nrSSU, rpb1 , rpb2 , and tef1-α . Additionally, morphological examinations were also carried out...
March 18, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535076/assessing-patient-radiation-exposure-in-endoscopic-retrograde-cholangiopancreatography-a-multicenter-retrospective-analysis-of-procedural-complexity-and-clinical-factors
#26
JOURNAL ARTICLE
Touko Kaasalainen, Ekaterina Saukko, Outi Lindström, Marianne Udd, Sara Regnér, Arto Saarela, Ervin Toth, Gabriele Wurm Johansson, Anna-Leena Manninen, Juha Grönroos, Leena Kylänpää
BACKGROUND AND AIMS: Endoscopic retrograde cholangiopancreatography (ERCP) procedures can result in significant patient radiation exposure. This retrospective multicenter study aimed to assess the influence of procedural complexity and other clinical factors on radiation exposure in ERCP. METHODS: Data on kerma-area product (KAP), air-kerma at the reference point (Ka,r ), fluoroscopy time, and the number of exposures, and relevant patient, procedure, and operator factors were collected from 2641 ERCP procedures performed at four university hospitals...
March 21, 2024: Diagnostics
https://read.qxmd.com/read/38533806/improved-effectiveness-of-x-pdt-against-human-triple-negative-breast-cancer-cells-through-the-use-of-liposomes-co-loaded-with-protoporphyrin-ix-and-perfluorooctyl-bromide
#27
JOURNAL ARTICLE
Biyao Yang, Rui Sang, Yi Li, Ewa M Goldys, Wei Deng
In this study, we utilized X-ray-induced photodynamic therapy (X-PDT) against triple-negative breast cancer (TNBC) cells. To achieve this, we developed a liposome delivery system that co-loaded protoporphyrin IX (PPIX) and perfluorooctyl bromide (PFOB) in a rational manner. Low-dose X-ray at 2 Gy was employed to activate PPIX for the generation of reactive oxygen species (ROS), and the co-loading of PFOB provided additional oxygen to enhance ROS production. The resulting highly toxic ROS effectively induced cell death in TNBC...
March 27, 2024: Journal of Materials Chemistry. B, Materials for Biology and Medicine
https://read.qxmd.com/read/38533398/identification-of-qtls-associated-with-seed-protein-concentration-in-two-diverse-recombinant-inbred-line-populations-of-pea
#28
JOURNAL ARTICLE
Krishna Kishore Gali, Ambuj Jha, Bunyamain Tar'an, Judith Burstin, Gregoire Aubert, Dengjin Bing, Gene Arganosa, Thomas D Warkentin
Improving the seed protein concentration (SPC) of pea ( Pisum sativum L.) has turned into an important breeding objective because of the consumer demand for plant-based protein and demand from protein fractionation industries. To support the marker-assisted selection (MAS) of SPC towards accelerated breeding of improved cultivars, we have explored two diverse recombinant inbred line (RIL) populations to identify the quantitative trait loci (QTLs) associated with SPC. The two RIL populations, MP 1918 × P0540-91 (PR-30) and Ballet × Cameor (PR-31), were derived from crosses between moderate SPC × high SPC accessions...
2024: Frontiers in Plant Science
https://read.qxmd.com/read/38533370/b-ultrasound-or-ct-guided-3d-printing-individualized-non-coplanar-template-brachytherapy-for-the-treatment-of-locally-uncontrolled-recurrent-head-and-neck-squamous-cell-carcinoma
#29
JOURNAL ARTICLE
Pengbing Han, Fengju Li, Yanping Zhang, Liying Gao, Guiqiong Zhang, Qing Guo, Yuxia Zhu, Qun Su
INTRODUCTION: It is worth to explore a more effective treatment method to minimize the damage for patients during the treatment process. AIM: To explore the method, feasibility and efficacy of B-ultrasound or computed tomography (CT)-guided 3D printing individualized non-coplanar template brachytherapy in the treatment of locally uncontrolled recurrent head and neck squamous cell carcinoma. MATERIAL AND METHODS: Ten patients with locally uncontrolled recurrent head and neck squamous cell carcinoma who were treated in our department from August 2021 to February 2023 were collected and treated by 3D printing individualized non-coplanar template brachytherapy under the guidance of B-ultrasound or CT, using the 192Ir high-dose rate afterloading treatment machine of NUCLETRON Technologies GmbH...
February 2024: Postȩpy Dermatologii i Alergologii
https://read.qxmd.com/read/38532338/carbon-ion-radiotherapy-for-hepatocellular-carcinoma-with-major-vascular-invasion-a-retrospective-cohort-study
#30
JOURNAL ARTICLE
Takashi Kaneko, Hirokazu Makishima, Masaru Wakatsuki, Yuichi Hiroshima, Toshiaki Matsui, Shigeo Yasuda, Naomi Nagatake Okada, Kenji Nemoto, Hiroshi Tsuji, Shigeru Yamada, Masaru Miyazaki
BACKGROUND: Macroscopic vascular invasion (MVI) significantly impacts survival in patients with hepatocellular carcinoma (HCC), warranting systemic therapy over locoregional therapy. Despite novel approaches, HCC with MVI has a poor prognosis compared to early-to intermediate-stage HCC. This study aimed to evaluate the safety and efficacy of carbon-ion radiotherapy (C-ion RT) for HCC characterized by MVI. METHODS: This retrospective cohort study evaluated HCC patients with MVI treated using C-ion RT with a dose of 45...
March 26, 2024: BMC Cancer
https://read.qxmd.com/read/38530837/how-does-ionizing-radiation-affect-amyloidogenesis-in-plants
#31
JOURNAL ARTICLE
Maryna Kryvokhyzha, Sergii Litvinov, Maksym Danchenko, Lidiia Khudolieieva, Nataliia Kutsokon, Peter Baráth, Namik Rashydov
PURPOSE: Ionizing radiation is a harsh environmental factor that could induce plant senescence. We hypothesized that radiation-related senescence remodels proteome, particularly by triggering the accumulation of prion-like proteins in plant tissues. The object of this study, pea ( Pisum sativum L.), is an agriculturally important legume. Research on the functional importance of amyloidogenic proteins was never performed on this species. MATERIALS AND METHODS: Pea seeds were irradiated in the dose range 5-50 Gy of X-rays...
March 26, 2024: International Journal of Radiation Biology
https://read.qxmd.com/read/38530254/concurrent-atezolizumab-plus-bevacizumab-and-high-dose-external-beam-radiotherapy-for-highly-advanced-hepatocellular-carcinoma
#32
JOURNAL ARTICLE
Chung-Wei Su, Wei Teng, Eric Yi-Liang Shen, Bing-Shen Huang, Po-Ting Lin, Ming-Mo Hou, Tsung-Han Wu, Din-Li Tsan, Chia-Hsun Hsieh, Ching-Ting Wang, Pei-Mei Chai, Chun-Yen Lin, Shi-Ming Lin, Chen-Chun Lin
BACKGROUND: Atezolizumab plus bevacizumab (atezo-bev) has been recommended for advanced hepatocellular carcinoma (HCC). High-dose external beam radiotherapy (RT) is recognized for its excellent local tumor control. The efficacy and safety of concurrent atezo-bev with RT for highly advanced HCC has been minimally explored. METHODS: In this preliminary retrospective study, we assessed patients with highly advanced HCC, characterized by Vp4 portal vein thrombosis or tumors exceeding 50% of liver volume, who received concurrent atezo-bev and RT (group A)...
March 26, 2024: Oncologist
https://read.qxmd.com/read/38529591/five-fraction-high-conformal-ultrahypofractionated-radiotherapy-for-primary-tumors-in-metastatic-breast-cancer
#33
JOURNAL ARTICLE
Jeongshim Lee, Jee Hung Kim, Mitchell Liu, Andrew Bang, Robert Olson, Jee Suk Chang
PURPOSE: To report on the local control and toxicity of 5-fraction, high-conformal ultrafractionated radiation therapy (RT) for primary tumors in patients with metastatic breast cancer (MBC) who did not undergo planned surgical intervention. METHODS: We retrospectively reviewed 27 patients with MBC who underwent 5-fraction high-dose ultrafractionated intensity-modulated RT for their primary tumors between 2017 and 2022 at our institution. A median dose of 66.8 Gy (range, 51...
March 26, 2024: Journal of Breast Cancer
https://read.qxmd.com/read/38529590/hypofractionated-partial-breast-irradiation-with-intensity-modulated-radiotherapy-in-early-breast-cancer-or-carcinoma-in-situ-an-investigational-short-term-analysis
#34
JOURNAL ARTICLE
Nam Kyu Kang, Soo-Yoon Sung, Sung Hwan Kim, Ye Won Jeon, Young Jin Suh, Jong Hoon Lee
PURPOSE: This study aimed to analyze the treatment outcomes and adverse effects of moderately hypofractionated partial breast irradiation (PBI) in patients with early breast cancer. METHODS: In total, 473 patients with early breast cancer or carcinoma in situ were diagnosed with Tis or T1N0 disease and underwent PBI following breast-conserving surgery. All histologic tumor types, close surgical margins within 1 mm of the tumor, and multifocal tumors were included in this study...
March 26, 2024: Journal of Breast Cancer
https://read.qxmd.com/read/38528990/effects-of-paternal-ionizing-radiation-exposure-on-fertility-and-offspring-s-health
#35
JOURNAL ARTICLE
Jiaqun Li, Juan Liu, Yanye Zhang, Hong Qiu, Junyan Zheng, Jinglei Xue, Jiani Jin, Feida Ni, Chunxi Zhang, Chuan Chen, Xiao Sun, Huiquan Wang, Dan Zhang
PURPOSE: The intergenerational effects of ionizing radiation remain controversial. Extensive insights have been revealed for DNA mutations and cancer incidence in progeny, yet many of these results were obtained by immediate post-radiation mating. However, conception at short times after radiation exposure is likely to be avoided. After a long period of fertility recovery, whether unexposed sperm derived from exposed spermatogonia would challenge the health of the offspring is not yet clearly demonstrated...
2024: Reproductive Medicine and Biology
https://read.qxmd.com/read/38528774/are-oral-cancers-effectively-palliated-with-radiotherapy-outcomes-of-treatment-with-a-modified-quad-shot-regimen
#36
JOURNAL ARTICLE
Saheli Saha, Indranil Mallick, Prattusha Mukherjee, Santam Chakraborty, Tapesh Bhattacharyya, Moses Arunsingh S, Rimpa Basu Achari, Sanjoy Chatterjee
BACKGROUND: This study assessed a palliative radiotherapy regimen using daily radiation over 4 days for three courses in inoperable head and neck cancers, emphasizing oral primary cancers. METHODS: Retrospective data of 116 patients treated with a daily dose of 3.6-3.7 Gy in four fractions over 4 days to a total of three courses, with a 2-week gap after every course, were analyzed for survival outcomes. A subgroup analysis was done for oral cancer...
March 25, 2024: Head & Neck
https://read.qxmd.com/read/38528587/single-cell-rna-sequencing-reveals-recruitment-of-the-m2-like-ccl8-high-macrophages-in-lewis-lung-carcinoma-bearing-mice-following-hypofractionated-radiotherapy
#37
JOURNAL ARTICLE
Haonan Yang, Zheng Lei, Jiang He, Lu Zhang, Tangmin Lai, Liu Zhou, Nuohan Wang, Zheng Tang, Jiangdong Sui, Yongzhong Wu
BACKGROUND: Tumor-associated macrophages (TAMs) play a pivotal role in reshaping the tumor microenvironment following radiotherapy. The mechanisms underlying this reprogramming process remain to be elucidated. METHODS: Subcutaneous Lewis lung carcinoma (LLC) murine model was treated with hypofrationated radiotherapy (8 Gy × 3F). Single-cell RNA sequencing was utilized to identify subclusters and functions of TAMs. Multiplex assay and enzyme-linked immunosorbent assay (ELISA) were employed to measure serum chemokine levels...
March 25, 2024: Journal of Translational Medicine
https://read.qxmd.com/read/38528236/the-effect-of-dose-escalation-radiotherapy-with-simultaneous-integrated-boost-on-the-use-of-short-term-androgen-deprivation-therapy-in-patients-with-intermediate-risk-prostate-cancer
#38
JOURNAL ARTICLE
Cem Onal, Ozan Cem Guler, Gurcan Erbay, Aysenur Elmali
PURPOSE: To compare the biochemical failure (FFBF) and prostate cancer specific survival (PCSS) rates of patients with intermediate-risk prostate cancer (IR-PC) who were treated with 6 months of androgen deprivation therapy (ADT) with 78 Gy to the prostate, those treated with ADT and focal boost (FB) of 86 Gy to intraprostatic lesion (IPL) using the simultaneous-integrated boost (SIB) technique, and those treated with SIB alone. MATERIALS AND METHODS: A retrospective analysis of 320 IR-PC patients treated between January 2012 and April 2021 was performed...
March 25, 2024: Prostate
https://read.qxmd.com/read/38528164/dosimetry-and-pharmacokinetics-of-177-lu-lu-satoreotide-tetraxetan-in-patients-with-progressive-neuroendocrine-tumours
#39
JOURNAL ARTICLE
Seval Beykan Schürrle, Uta Eberlein, Catherine Ansquer, Jean-Mathieu Beauregard, Lucie Durand-Gasselin, Henning Grønbæk, Alexander Haug, Rodney J Hicks, Nat P Lenzo, Shaunak Navalkissoor, Guillaume P Nicolas, Ben Pais, Magali Volteau, Damian Wild, Alexander McEwan, Michael Lassmann
PURPOSE: To evaluate the dosimetry and pharmacokinetics of the novel radiolabelled somatostatin receptor antagonist [177 Lu]Lu-satoreotide tetraxetan in patients with advanced neuroendocrine tumours (NETs). METHODS: This study was part of a phase I/II trial of [177 Lu]Lu-satoreotide tetraxetan, administered at a median cumulative activity of 13.0 GBq over three planned cycles (median activity/cycle: 4.5 GBq), in 40 patients with progressive NETs. Organ absorbed doses were monitored at each cycle using patient-specific dosimetry; the cumulative absorbed-dose limits were set at 23...
March 26, 2024: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/38527626/infrared-microspectroscopy-to-elucidate-the-underlying-biomolecular-mechanisms-of-flash-radiotherapy
#40
JOURNAL ARTICLE
Immaculada Martínez-Rovira, Pierre Montay-Gruel, Benoît Petit, Ron Leavitt, Roberto González-Vegas, Pascal Froidevaux, Marjorie Juchaux, Yolanda Prezado, Ibraheem Yousef, Marie-Catherine Vozenin
BACKGROUND: FLASH-radiotherapy (FLASH-RT) is an emerging modality that uses ultra-high dose rates of radiation to enable curative doses to the tumor while preserving normal tissue. The biological studies showed the potential of FLASH-RT to revolutionize radiotherapy cancer treatments. However, the complex biological basis of FLASH-RT is not fully known yet. AIM: Within this context, our aim is to get deeper insights into the biomolecular mechanisms underlying FLASH-RT through Fourier Transform Infrared Microspectroscopy (FTIRM)...
March 23, 2024: Radiotherapy and Oncology
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