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Miriam B Vos, Stephanie H Abrams, Sarah E Barlow, Sonia Caprio, Stephen R Daniels, Rohit Kohli, Marialena Mouzaki, Pushpa Sathya, Jeffrey B Schwimmer, Shikha S Sundaram, Stavra A Xanthakos
Nonalcoholic fatty liver disease (NAFLD) is a highly prevalent chronic liver disease that occurs in the setting of insulin resistance and increased adiposity. It has rapidly evolved into the most common liver disease seen in the pediatric population and is a management challenge for general pediatric practitioners, subspecialists and for health systems. In this guideline, the expert committee on NAFLD (ECON) reviewed and summarized the available literature, formulating recommendations to guide screening and clinical care of children with NAFLD...
November 30, 2016: Journal of Pediatric Gastroenterology and Nutrition
L Rodriguez, M Sood, C Di Lorenzo, M Saps
BACKGROUND: Over the last few years, the study of the colon and anorectal function has experienced great technical advances that have facilitated the performance of the tests and have allowed a more detailed characterization of reflexes and motor patterns. As a result, we have achieved a much better understanding of the pathophysiology of children with defecation problems. Anorectal and colonic manometry are now commonly used in all major pediatric referral centers as diagnostic tools and to guide the management of children with intractable constipation and fecal incontinence, particularly when a surgical intervention is being considered...
October 9, 2016: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
Joel A Friedlander, Quin Y Liu, Benjamin Sahn, Koorosh Kooros, Catharine M Walsh, Robert E Kramer, Jenifer R Lightdale, Julie Khlevner, Mark McOmber, Jacob Kurowski, Matthew J Giefer, Harpreet Pall, David M Troendle, Elizabeth C Utterson, Herbert Brill, George M Zacur, Richard A Lirio, Diana G Lerner, Carrie Reynolds, Troy E Gibbons, Michael Wilsey, Chris A Liacouras, Douglas S Fishman
Wireless capsule endoscopy (CE) was introduced in 2000 as a less invasive method to visualize the distal small bowel in adults. As this technology has advanced it has been adapted for use in pediatric gastroenterology. Several studies have described its clinical use, utility, and various training methods but pediatric literature regarding capsule endoscopy is limited. This clinical report developed by the Endoscopic and Procedures Committee of the North American Society of Pediatric Gastroenterology, Hepatology, and Nutrition outlines the current literature, and describes the recommended current role, use, training, and future areas of research for CE in pediatrics...
September 16, 2016: Journal of Pediatric Gastroenterology and Nutrition
Usha Krishnan, Hayat Mousa, Luigi Dall'Oglio, Nusrat Homaira, Rachel Rosen, Christophe Faure, Frédéric Gottrand
BACKGROUND: Esophageal atresia (EA) is one of the most common congenital digestive anomalies. With improvements in surgical techniques and intensive care treatments, the focus of care of these patients has shifted from mortality to morbidity and quality-of-life issues. These children face gastrointestinal (GI) problems not only in early childhood but also through adolescence and adulthood. There is, however, currently a lack of a systematic approach to the care of these patients. The GI working group of International Network on Esophageal Atresia comprises members from ESPGHAN/NASPGHAN and was charged with the task of developing uniform evidence-based guidelines for the management of GI complications in children with EA...
November 2016: Journal of Pediatric Gastroenterology and Nutrition
Tom K Lin, David M Troendle, Daniel B Wallihan, Bradley Barth, Victor L Fox, Douglas S Fishman, Veronique D Morinville
OBJECTIVES: An increasing number of children are being diagnosed with pancreatitis and other pancreatic abnormalities. Dissemination of the information regarding existing imaging techniques and endoscopic modalities to diagnose and manage pancreatic disorders in children is sorely needed. METHODS: We conducted a review of the medical literature on the use of the following imaging and procedural modalities in pediatric pancreatology: transabdominal ultrasonography (TUS), computed tomography (CT), magnetic resonance imaging (MRI)- magnetic resonance cholangiopancreatography (MRCP), endoscopic ultrasonography (EUS), endoscopic retrograde cholangiopancreatography (ERCP)...
August 6, 2016: Journal of Pediatric Gastroenterology and Nutrition
Rima Fawaz, Ulrich Baumann, Udeme Ekong, Björn Fischler, Nedim Hadzic, Cara L Mack, Valérie A McLin, Jean P Molleston, Ezequiel Neimark, Vicky Lee Ng, Saul J Karpen
Cholestatic jaundice in infancy affects approximately 1 in every 2500 term infants and is infrequently recognized by primary providers in the setting of physiologic jaundice. Cholestatic jaundice is always pathologic and indicates hepatobiliary dysfunction. Early detection by the primary care physician and timely referrals to the pediatric gastroenterologist/hepatologist are important contributors to optimal treatment and prognosis. The most common causes of cholestatic jaundice in the first months of life are biliary atresia (BA, 25-40%) followed by an expanding list of monogenic disorders (25%), plus many unknown or multifactorial (e...
July 16, 2016: Journal of Pediatric Gastroenterology and Nutrition
Ann Scheimann
No abstract text is available yet for this article.
September 2016: Journal of Pediatric Gastroenterology and Nutrition
Inderpreet Grover, Richard Kim, Danielle C Spree, Christopher J Lahr, Archana Kedar, Shivangi Kothari, David Fleisher, Thomas L Abell
Background/Aims: Cyclic vomiting syndrome (CVS) is a disabling migraine variant manifesting as severe episodes of nausea and vomiting and often refractory to many therapies. Gastric electrical stimulation (GES), which can reduce nausea and vomiting in gastroparesis, may provide symptomatic relief for drug-refractory CVS. This study assessed the utility GES in reducing the symptoms of CVS and improving quality of life. Methods: A one-year, non-randomized, clinical study was conducted...
May 30, 2016: Journal of Neurogastroenterology and Motility
Jonas F Ludvigsson, Lars Agreus, Carolina Ciacci, Sheila E Crowe, Marilyn G Geller, Peter H R Green, Ivor Hill, A Pali Hungin, Sibylle Koletzko, Tunde Koltai, Knut E A Lundin, M Luisa Mearin, Joseph A Murray, Norelle Reilly, Marjorie M Walker, David S Sanders, Raanan Shamir, Riccardo Troncone, Steffen Husby
The process of transition from childhood to adulthood is characterised by physical, mental and psychosocial development. Data on the transition and transfer of care in adolescents/young adults with coeliac disease (CD) are scarce. In this paper, 17 physicians from 10 countries (Sweden, Italy, the USA, Germany, Norway, the Netherlands, Australia, Britain, Israel and Denmark) and two representatives from patient organisations (Association of European Coeliac Societies and the US Celiac Disease Foundation) examined the literature on transition from childhood to adulthood in CD...
August 2016: Gut
Ivor D Hill, Alessio Fasano, Stefano Guandalini, Edward Hoffenberg, Joseph Levy, Norelle Reilly, Ritu Verma
Dietary exclusion of gluten-containing products has become increasingly popular in the general population, and currently ∼30% of people in the United States are limiting gluten ingestion. Although celiac disease (CD), wheat allergy (WA), and nonceliac gluten sensitivity (NCGS) constitute a spectrum of gluten-related disorders that require exclusion of gluten from the diet, together these account for a relatively small percentage of those following a gluten-free diet, and the vast majority has no medical necessity for doing so...
July 2016: Journal of Pediatric Gastroenterology and Nutrition
Rachel Bensen, Rebecca B McKenzie, Susan M Fernandes, Laurie N Fishman
OBJECTIVES: Transition and transfer to adult-oriented health care is an important yet challenging task for adolescents and young adults with chronic medical conditions. Transition practices vary widely, but a paucity of data makes determination of best practices difficult. We described North American pediatric gastroenterologists' preferences and present transition practice patterns and explored whether experience affected providers' perspectives. METHODS: An online survey was distributed via e-mail to members of the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition...
November 2016: Journal of Pediatric Gastroenterology and Nutrition
Monica I Ardura, Sima S Toussi, Jane D Siegel, Ying Lu, Athos Bousvaros, Wallace Crandall
Children and adolescents with inflammatory bowel disease (IBD) receiving therapy with tumor necrosis factor α inhibitors (anti-TNFα) pose a unique challenge to health care providers in regard to the associated risk of infection. Published experience in adult populations with distinct autoinflammatory and autoimmune diseases treated with anti-TNFα therapies demonstrates an increased risk of serious infections with intracellular bacteria, mycobacteria, fungi, and some viruses; however, there is a paucity of robust pediatric data...
July 2016: Journal of Pediatric Gastroenterology and Nutrition
Jin Huan Lin, Jun Fang, Dong Wang, He Zhong Chen, Qiang Guo, Xue Gang Guo, Shu Tang Han, Li Ping He, Shui Xiang He, Hui Qing Jiang, Zhen Dong Jin, Xun Li, Zhuan Liao, Bing Mei, Xu Ren, Yong Jin Tang, Bang Mao Wang, Li Wang, Hong Xu, Lei Ming Xu, Xu Chao Xue, Yu Xiu Yang, Xiao Feng Zhang, Zi Qi Zhang, Hong Liang Zheng, Fa Chao Zhi, Liang Zhong, Duo Wu Zou, Xiao Ping Zou, Zhao Shen Li
No abstract text is available yet for this article.
February 2016: Journal of Digestive Diseases
Ödül Egritaş Gürkan, Aysel Ünlüsoy Aksu, Zeliha Demirtaş, Buket Dalgıç
BACKGROUND/AIMS: Considering the etiology of cyclic vomiting syndrome (CVS) in childhood, a variety of underlying organic causes has been clearly identified in the literature. The aim of this study was to emphasize that endoscopic evaluation in the first step may help diagnosis and treatment in patients with CVS, unlike the CVS-related "North American Society for Pediatric Gastroenterology, Hepatology and Nutrition" (NASPGHAN) consensus statement in 2008. MATERIALS AND METHODS: The medical files of patients with vomiting complaints admitted to our tertiary center between the years 2007 and 2012 were analyzed retrospectively...
November 2015: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
I Xinias, A Mavroudi
OBJECTIVE: Constipation is a frequent problitalic in childhood and may be defined as delay or difficulty in defecation that persists for longer than two weeks. It is one of the ten most frequent pathological conditions that a general paediatrician deals with. The aim of this review is to provide the general paediatrician an overview of constipation in children discussing the etiology, differential diagnosis, signs and symptoms and patient evaluation. METHODS: We provide an overview on the pathogenesis, the diagnostic approach and the managitalicent of constipation based on electronic literature searches using the best available evidence from PubMed, Medline, Google Scholar, the European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN)...
January 2015: Hippokratia
Christopher J Taylor, Kathy Chen, Karoly Horvath, David Hughes, Mark E Lowe, Devendra Mehta, Abrahim I Orabi, Jeremy Screws, Mike Thomson, Stephanie Van Biervliet, Henkjan J Verkade, Sohail Z Husain, Michael Wilschanski
The purpose of this clinical report is to discuss several recent advances in assessing exocrine pancreatic insufficiency (EPI) and pancreatitis in children, to review the array of pancreatic function tests, to provide an update on the inherited causes of EPI, with special emphasis on newly available genetic testing, and to review newer methods for evaluating pancreatitis.
July 2015: Journal of Pediatric Gastroenterology and Nutrition
Emily Senerth
No abstract text is available yet for this article.
May 2015: Journal of Pediatric Gastroenterology and Nutrition
Christine H Yang, Jaya Punati
OBJECTIVES: The North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition has formulated guidelines for managing functional constipation. There have been no studies that have investigated how pediatricians apply the constipation guideline since it was revised in 2006. The purpose of this study was to examine how pediatricians approach functional constipation and how closely their approaches adhere to the guidelines. METHODS: An anonymous multiple-choice questionnaire was developed by general pediatricians and pediatric gastroenterologists...
March 2015: Journal of Pediatric Gastroenterology and Nutrition
Robert E Kramer, Diana G Lerner, Tom Lin, Michael Manfredi, Manoj Shah, Thomas C Stephen, Troy E Gibbons, Harpreet Pall, Ben Sahn, Mark McOmber, George Zacur, Joel Friedlander, Antonio J Quiros, Douglas S Fishman, Petar Mamula
Foreign body ingestions in children are some of the most challenging clinical scenarios facing pediatric gastroenterologists. Determining the indications and timing for intervention requires assessment of patient size, type of object ingested, location, clinical symptoms, time since ingestion, and myriad other factors. Often the easiest and least anxiety-producing decision is the one to proceed to endoscopic removal, instead of observation alone. Because of variability in pediatric patient size, there are less firm guidelines available to determine which type of object will safely pass, as opposed to the clearer guidelines in the adult population...
April 2015: Journal of Pediatric Gastroenterology and Nutrition
Nicolas Kalach, Patrick Bontems, Samy Cadranel
In this review we elaborate on two main questions concerning the management of Helicobacter pylori infection in children. First, we focus on who should be treated. In the presence of Helicobacter pylori (H. pylori)-associated peptic ulcer disease, eradication of the micro-organism is recommended. When H. pylori infection is detected by biopsy-based methods in the absence of peptic ulcer disease in a child with dyspeptic symptoms, treatment of H. pylori infection may be considered. In infected children whose first degree relatives have gastric cancer, treatment can be offered...
January 2015: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
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