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https://www.readbyqxmd.com/read/29778078/an-effective-and-low-cost-carbon-based-clean-up-method-for-pcdd-fs-and-pcbs-analysis-in-food
#1
Kleopatra Kedikoglou, Danae Costopoulou, Irene Vassiliadou, Evangelos Bakeas, Leondios Leondiadis
Sample preparation is of critical importance in dioxin analysis of food and feed samples. It is a complex procedure that includes lipid extraction followed by the application of chromatographic separation techniques, aiming in removing undesirable interferences from the matrix. The separation of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) from polychlorinated biphenyls (PCBs) is achieved by carbon-based materials which should have high fat capacity in order to be suitable for lipid-containing matrices...
May 7, 2018: Chemosphere
https://www.readbyqxmd.com/read/29778073/non-selective-rapid-electro-oxidation-of-persistent-refractory-vocs-in-industrial-wastewater-using-a-highly-catalytic-and-dimensionally-stable-irpd-ti-composite-electrode
#2
Wan-Cheol Cho, Kyung-Min Poo, Hend Omar Mohamed, Tae-Nam Kim, Yul-Seong Kim, Moon Hyun Hwang, Do-Won Jung, Kyu-Jung Chae
Volatile organic compounds (VOCs) are highly toxic contaminants commonly dissolved in industrial wastewater. Therefore, treatment of VOC-containing wastewater requires a robust and rapid reaction because liquid VOCs can become volatile secondary pollutants. In this study, electro-oxidation with catalytic composite dimensionally stable anodes (DSAs)-a promising process for degrading organic pollutants-was applied to remove various VOCs (chloroform, benzene, toluene, and trichloroethylene). Excellent treatment efficiency of VOCs was demonstrated...
May 11, 2018: Chemosphere
https://www.readbyqxmd.com/read/29776627/introduction-molecular-medicine-in-the-common-era-applications-and-impact-of-molecular-pathology-in-health-and-disease
#3
REVIEW
Martin H Bluth
The unprecedented expansion of molecular pathology continues to affect and influence the clinical laboratory. Technological advances in high-throughput automation, cost containment, and refined methodology have improved the understanding of pathobiology through application of molecular pathology to multiple disease spaces. Incorporation of this field to emerging omics platforms, pharmacovigilance and biomarker discovery, and accessibility by lay consumers demonstrates the widespread reach of molecular pathology in the clinical marketplace...
June 2018: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29776399/simulation-based-power-calculations-for-planning-a-two-stage-individual-participant-data-meta-analysis
#4
Joie Ensor, Danielle L Burke, Kym I E Snell, Karla Hemming, Richard D Riley
BACKGROUND: Researchers and funders should consider the statistical power of planned Individual Participant Data (IPD) meta-analysis projects, as they are often time-consuming and costly. We propose simulation-based power calculations utilising a two-stage framework, and illustrate the approach for a planned IPD meta-analysis of randomised trials with continuous outcomes where the aim is to identify treatment-covariate interactions. METHODS: The simulation approach has four steps: (i) specify an underlying (data generating) statistical model for trials in the IPD meta-analysis; (ii) use readily available information (e...
May 18, 2018: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/29776104/interplay-between-cost-and-benefits-triggers-nontrivial-vaccination-uptake
#5
Benjamin Steinegger, Alessio Cardillo, Paolo De Los Rios, Jesús Gómez-Gardeñes, Alex Arenas
The containment of epidemic spreading is a major challenge in science. Vaccination, whenever available, is the best way to prevent the spreading, because it eventually immunizes individuals. However, vaccines are not perfect, and total immunization is not guaranteed. Imperfect immunization has driven the emergence of antivaccine movements that totally alter the predictions about the epidemic incidence. Here, we propose a mathematically solvable mean-field vaccination model to mimic the spontaneous adoption of vaccines against influenzalike diseases and the expected epidemic incidence...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29775275/a-high-performance-and-recyclable-al-air-coin-cell-based-on-eco-friendly-chitosan-hydrogel-membranes
#6
Yisi Liu, Qian Sun, Xiaofei Yang, Jianneng Liang, Biqiong Wang, Alicia Koo, Ruying Li, Jie Li, Xueliang Sun
Aluminum-air batteries are a promising power supply for electronics due to its low cost and high energy density. However, portable coin-type Al-air batteries operating under ambient air condition for small electronic appliances have rarely been reported. Herein, coin cell-type Al-air batteries using cost-effective and eco-friendly chitosan hydrogel membranes modified by SiO2, SnO2, and ZnO have been prepared and assembled. The Al-air coin cell employing chitosan hydrogel membrane containing 10 wt.% SiO2 as a separator exhibits better discharge performance with a higher flat voltage plateau, longer discharge duration, and higher power density than the cells using a chitosan hydrogel membrane containing SnO2 or ZnO...
May 18, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29774828/bilberry-pomace-in-rabbit-nutrition-effects-on-growth-performance-apparent-digestibility-caecal-traits-bacterial-community-and-antioxidant-status
#7
S Dabbou, I Ferrocino, A Kovitvadhi, S Bergagna, D Dezzuto, A Schiavone, L Cocolin, F Gai, V Santoro, L Gasco
Agricultural by-products could be used as alternative raw materials in rabbit nutrition as they have been found to be highly nutritious and low cost feeding sources. The aim of this study was to estimate the nutritive value and potential use of bilberry pomace (BP) for growing rabbits. A total of 144 Grimaud rabbits (35 days old) were allotted to four groups and fed with a diet containing increasing level of BP: BP0 (basal diet), BP5, BP10 and BP15 containing 0, 50, 100 and 150 g/kg respectively. Growth trial lasted 48 days; apparent digestibility was evaluated, starting at 46 days of age, over 4 consecutive days...
May 18, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29774633/a-simple-and-cost-efficient-adherent-culture-platform-for-human-gastric-primary-cells-as-an-in-vitro-model-for-helicobacter-pylori-infection
#8
Samaneh Saberi, Behshad Pournasr, Zahra Farzaneh, Maryam Esmaeili, Mahmoud Eshagh Hosseini, Hossein Baharvand, Marjan Mohammadi
BACKGROUND: Most two- dimensional in vitro models for studying host- H. pylori interactions rely on tumor-derived cell lines, which harbor malignant alterations. The recent development of human gastric organoids has overcome this limitation and provides a highly sophisticated, yet costly, short-term model for H. pylori infection, with restricted use in low-budget centers. METHOD: Tissue specimens from upper, middle, and lower stomachs of H. pylori-negative volunteers were collectively dispersed and cultured on mouse embryonic fibroblast (MEF) or collagen-coated plates...
May 17, 2018: Helicobacter
https://www.readbyqxmd.com/read/29774415/development-of-a-cost-effective-production-process-for-halomonas-levan
#9
Burak Adnan Erkorkmaz, Onur Kırtel, Özlem Ateş Duru, Ebru Toksoy Öner
Levan polysaccharide is an industrially important natural polymer with unique properties and diverse high-value applications. However, current bottlenecks associated with its large-scale production need to be overcome by innovative approaches leading to economically viable processes. Besides many mesophilic levan producers, halophilic Halomonas smyrnensis cultures hold distinctive industrial potential and, for the first time with this study, the advantage of halophilicity is used and conditions for non-sterile levan production were optimized...
May 17, 2018: Bioprocess and Biosystems Engineering
https://www.readbyqxmd.com/read/29772681/global-asbestos-disaster
#10
Sugio Furuya, Odgerel Chimed-Ochir, Ken Takahashi, Annette David, Jukka Takala
Introduction : Asbestos has been used for thousands of years but only at a large industrial scale for about 100⁻150 years. The first identified disease was asbestosis, a type of incurable pneumoconiosis caused by asbestos dust and fibres. The latest estimate of global number of asbestosis deaths from the Global Burden of Disease estimate 2016 is 3495. Asbestos-caused cancer was identified in the late 1930's but despite today's overwhelming evidence of the strong carcinogenicity of all asbestos types, including chrysotile, it is still widely used globally...
May 16, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29772375/duplex-functional-g-quadruplex-nmm-fluorescent-probe-for-label-free-detection-of-lead-ii-and-mercury-ii-ions
#11
Qian Zhu, Lanhua Liu, Yunpeng Xing, Xiaohong Zhou
To meet the severe water pollution status, multi-target biosensor becomes one of research focus. We herein report a novel duplex functional fluorescent biosensor for the label-free and separate detection of Pb2+ and Hg2+ with high sensitivity and selectivity. A K+ -induced fluorescent G-quadruplex probe was assembled by a guanine-rich sequence (AGRO100) and N-methyl mesoporphyrin IX(NMM). It changed into a more stably non-fluorescent G-quadruplex structure and a hairpin-like structure upon binding Pb2+ and Hg2+ ions, respectively...
May 1, 2018: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29771516/adaptive-geometric-networks-for-efficient-coarse-grained-ab-initio-molecular-dynamics-with-post-hartree-fock-accuracy
#12
Timothy C Ricard, Cody Haycraft, Srinivasan Sesha Iyengar
We introduce a new coarse-graining technique for ab initio molecular dynamics that is based on the adaptive generation of connected geometric networks or graphs specific to a given molecular ge- ometry. The coarse-grained nodes depict a local chemical environment and are networked to create edges, triangles, tetrahedrons and higher order simplexes based on (a) a Delaunay triangulation procedure and (b) a method that is based on molecular, bonded and non-bonded, local interac- tions. The geometric sub-entities thus created, that is nodes, edges, triangles, and tetrahedrons, each represent an energetic measure for a specific portion of the molecular system, capturing a spe- cific set of interactions...
May 17, 2018: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/29771371/allele-phasing-greatly-improves-the-phylogenetic-utility-of-ultraconserved-elements
#13
Tobias Andermann, Alexandre M Fernandes, Urban Olsson, Mats Töpel, Bernard Pfeil, Bengt Oxelman, Alexandre Aleixo, Brant C Faircloth, Alexandre Antonelli
Advances in high-throughput sequencing techniques now allow relatively easy and affordable sequencing of large portions of the genome, even for non-model organisms. Many phylogenetic studies reduce costs by focusing their sequencing efforts on a selected set of targeted loci, commonly enriched using sequence capture. The advantage of this approach is that it recovers a consistent set of loci, each with high sequencing depth, which leads to more confidence in the assembly of target sequences. High sequencing depth can also be used to identify phylogenetically informative allelic variation within sequenced individuals, but allele sequences are infrequently assembled in phylogenetic studies...
May 15, 2018: Systematic Biology
https://www.readbyqxmd.com/read/29771203/understanding-how-nurses-ration-care
#14
Clare Lynette Harvey, Shona Thompson, Eileen Willis, Alannah Meyer, Maria Pearson
Purpose The purpose of this paper is to explore how nurses make decisions to ration care or leave it undone within a clinical environment that is controlled by systems level cost containment. The authors wanted to find out what professional, personal and organisational factors contribute to that decision-making process. This work follows previous international research that explored missed nursing care using Kalisch and Williams' MISSCARE survey. Design/methodology/approach The authors drew on the care elements used by Kalisch and Williams, asking nurses to tell us how they decided what care to leave out, the conduits for which could include delaying care during a shift, delegating care to another health professional on the same shift, handing care over to staff on the next shift or leaving care undone...
May 21, 2018: Journal of Health Organization and Management
https://www.readbyqxmd.com/read/29770210/identification-of-publicly-available-data-sources-to-inform-the-conduct-of-health-technology-assessment-in-india
#15
Laura Downey, Neethi Rao, Lorna Guinness, Miqdad Asaria, Shankar Prinja, Anju Sinha, Rajni Kant, Arvind Pandey, Francoise Cluzeau, Kalipso Chalkidou
Background: Health technology assessment (HTA) provides a globally-accepted and structured approach to synthesising evidence for cost and clinical effectiveness alongside ethical and equity considerations to inform evidence-based priorities. India is one of the most recent countries to formally commit to institutionalising HTA as an integral component of the heath resource allocation decision-making process. The effective conduct of HTA depends on the availability of reliable data.   Methods : We draw from our experience of collecting, synthesizing, and analysing health-related datasets in India and internationally, to highlight the complex requirements for undertaking HTA, and explore the availability of such data in India...
2018: F1000Research
https://www.readbyqxmd.com/read/29768959/challenges-of-dispensing-costly-tablets-with-short-shelf-life
#16
Mário L de Lemos, Brittney Mathers, Nadine Badry, Linda Hamata, Kelly Lo
Afatinib, trametinib and regorafenib are three costly oral oncology drugs with a short shelf-life after the original container has been opened. Their short shelf-lives are due to degradation on exposure to moisture. Therefore, manufacturers recommend them to be dispensed in the original packaging with the desiccant. However, the prescribed quantities do not always match the quantities in the original packaging, usually because of dose modifications for toxicities. This leads to potentially significant drug wastage and financial losses...
January 1, 2018: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29768899/preparation-of-graphene-oxide-based-ink-for-inkjet-printing
#17
Peiwen Li, Cheng-An Tao, Bangyun Wang, Jian Huang, Taohai Li, Jianfang Wang
Fabrication of graphene-based conductive circuits via inkjet printing processes would be very significant, but preparation of graphene inks which can be used in ordinary household inkjet printer is still a challenge. Graphene oxide (GO) is an important graphene derivative with good dispersion properties in water, because it has a lot of oxygen-containing functional groups. In this paper, the relationship between the concentration of GO and the viscosity and surface tension of its dispersion were studied first, GO were prepared by modified Hummers' method...
January 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29768327/survival-benefit-of-neoadjuvant-chemotherapy-for-resectable-breast-cancer-a-meta-analysis
#18
Yan Chen, Xiu-E Shi, Jin-Hui Tian, Xu-Juan Yang, Yong-Feng Wang, Ke-Hu Yang
BACKGROUND: Neoadjuvant chemotherapy (NAC) increases breast conservation rates in patients with resectable breast cancer at the associated cost of higher locoregional recurrence rates; however, the magnitude of the survival benefits of NAC for these patients remains undefined. Therefore, we aimed to clarify the survival benefit of NAC versus postoperative chemotherapy by conducting an updated meta-analysis of randomized clinical trials (RCTs). METHODS: The authors searched the Cochrane Library, PubMed, Embase, Web of Science, Chinese biomedical literature database, and Chinese Scientific Journals full-text database from their inception to December 2016...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29768234/improved-experimental-time-of-ultra-large-bioassays-using-a-parallelised-microfluidic-biochip-architecture-scheduling
#19
Maryam Taajobian, Ali Jahanian
Digital microfluidic is an emerging technology to reduce the cost and time of experiments and improve the flexibility, automate-ability and correctness of biochemical assays. In many of applications such as drug discovery and DNA profiling, a large number of bio-operations (e.g. the chemical operations used in biology applications) must be done. In these applications, parallelising the operations will be critical in accuracy and cost of the process and digital microfluidic biochips can be considered as a reasonable platform...
June 2018: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29767699/impact-of-double-fortified-salt-with-iron-and-iodine-on-hemoglobin-anemia-and-iron-deficiency-anemia-a-systematic-review-and-meta-analysis
#20
María J Ramírez-Luzuriaga, Leila M Larson, Venkatesh Mannar, Reynaldo Martorell
Double-fortified salt (DFS) containing iron and iodine has been proposed as a feasible and cost-effective alternative for iron fortification in low- and middle-income countries (LMICs). We conducted a systematic review and meta-analysis from randomized and quasi-randomized controlled trials to 1) assess the effect of DFS on biomarkers of iron status and the risk of anemia and iron deficiency anemia (IDA) and 2) evaluate differential effects of DFS by study type (efficacy or effectiveness), population subgroups, iron formulation (ferrous sulfate, ferrous fumarate, and ferric pyrophosphate), iron concentration, duration of intervention, and study quality...
May 1, 2018: Advances in Nutrition
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