Ekaterina Maevskaia, Nupur Khera, Chafik Ghayor, Indranil Bhattacharya, Julien Guerrero, Flora Nicholls, Christian Waldvogel, Ralph Bärtschi, Lea Fritschi, Dániel Salamon, Mutlu Özcan, Patrick Malgaroli, Daniel Seiler, Michael de Wild, Franz E Weber
Autologous bone remains the gold standard bone substitute in clinical practice. Therefore, the microarchitecture of newly developed synthetic bone substitutes, which reflects the spatial distribution of materials in the scaffold, aims to recapitulate the natural bone microarchitecture. However, the natural bone microarchitecture is optimized to obtain a mechanically stable, lightweight structure adapted to the biomechanical loading situation. In the context of synthetic bone substitutes, the application of a Triply Periodic Minimum Surface (TPMS) algorithm can yield stable lightweight microarchitectures that, despite their demanding architectural complexity, can be produced by additive manufacturing...
October 1, 2023: 3D Printing and Additive Manufacturing