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https://www.readbyqxmd.com/read/27343794/perioperative-management-of-a-morbidly-obese-pregnant-patient-undergoing-cesarean-section-under-general-anesthesia-case-report
#1
Márcio Luiz Benevides, Verônica Cristina Moraes Brandão, Jacqueline Ivonne Arenas Lovera
BACKGROUND AND OBJECTIVES: The increased prevalence of obesity in the general population extends to women of reproductive age. The aim of this study is to report the perioperative management of a morbidly obese pregnant woman, body mass index >50kg/m(2), who underwent cesarean section under general anesthesia. CASE REPORT: Pregnant woman in labor, 35 years of age, body mass index 59.8kg/m(2). Cesarean section was indicated due to the presumed fetal macrosomia...
July 2016: Brazilian Journal of Anesthesiology
https://www.readbyqxmd.com/read/27108826/analysis-of-cricoid-pressure-application-anaesthetic-trainee-doctors-vs-nursing-anaesthetic-assistants
#2
Nurul Haizam Yahaya, Rufinah Teo, Azarinah Izaham, Shereen Tang, Aliza Mohamad Yusof, Norsidah Abdul Manap
BACKGROUND AND OBJECTIVE: To evaluate the ability of anaesthetic trainee doctors compared to nursing anaesthetic assistants in identifying the cricoid cartilage, applying the appropriate cricoid pressure and producing an adequate laryngeal inlet view. METHODS: Eighty-five participants, 42 anaesthetic trainee doctors and 43 nursing anaesthetic assistants, were asked to complete a set of questionnaires which included the correct amount of force to be applied to the cricoid cartilage...
May 2016: Brazilian Journal of Anesthesiology
https://www.readbyqxmd.com/read/27047453/species-specificity-of-bacteria-associated-to-the-brown-seaweeds-lobophora-dictyotales-phaeophyceae-and-their-potential-for-induction-of-rapid-coral-bleaching-in-acropora-muricata
#3
Christophe Vieira, Aschwin H Engelen, Linda Guentas, Tânia Aires, Fanny Houlbreque, Julie Gaubert, Ester A Serrão, Olivier De Clerck, Claude E Payri
While reef degradation is occurring worldwide, it is not uncommon to see phase shifts from coral to macroalgal dominated reefs. Numerous studies have addressed the mechanisms by which macroalgae may outcompete corals and a few recent studies highlighted the putative role of bacteria at the interface between macroalgae and corals. Some studies suggest that macroalgae may act as vectors and/or foster proliferation of microorganisms pathogenic for corals. Using a combination of high throughput sequencing, bacterial culturing, and in situ bioassays we question if the adversity of macroalgal-associated bacteria to corals is mediated by specific bacterial taxa...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/26993407/-analysis-of-cricoid-pressure-application-anaesthetic-trainee-doctors-vs-nursing-anaesthetic-assistants
#4
Nurul Haizam Yahaya, Rufinah Teo, Azarinah Izaham, Shereen Tang, Aliza Mohamad Yusof, Norsidah Abdul Manap
BACKGROUND AND OBJECTIVE: To evaluate the ability of anaesthetic trainee doctors compared to nursing anaesthetic assistants in identifying the cricoid cartilage, applying the appropriate cricoid pressure and producing an adequate laryngeal inlet view. METHODS: Eighty-five participants, 42 anaesthetic trainee doctors and 43 nursing anaesthetic assistants, were asked to complete a set of questionnaires which included the correct amount of force to be applied to the cricoid cartilage...
May 2016: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/26946020/matrix-effects-of-calcium-on-high-precision-sulfur-isotope-measurement-by-multiple-collector-inductively-coupled-plasma-mass-spectrometry
#5
Chenhui Liu, Xiao-Peng Bian, Tao Yang, An-Jun Lin, Shao-Yong Jiang
Multiple-collector inductively coupled plasma mass spectrometry (MC-ICP-MS) has been successfully applied in the rapid and high-precision measurement for sulfur isotope ratios in recent years. During the measurement, the presence of matrix elements would affect the instrumental mass bias for sulfur and these matrix-induced effects have aroused a lot of researchers' interest. However, these studies have placed more weight on highlighting the necessity for their proposed correction protocols (e.g., chemical purification and matrix-matching) while less attention on the key property of the matrix element gives rise to the matrix effects...
May 1, 2016: Talanta
https://www.readbyqxmd.com/read/26734245/improving-the-safety-of-remote-site-emergency-airway-management
#6
Julian Wijesuriya, Jonathan Brand
Airway management, particularly in non-theatre settings, is an area of anaesthesia and critical care associated with significant risk of morbidity & mortality, as highlighted during the 4th National Audit Project of the Royal College of Anaesthetists (NAP4). A survey of junior anaesthetists at our hospital highlighted a lack of confidence and perceived lack of safety in emergency airway management, especially in non-theatre settings. We developed and implemented a multifaceted airway package designed to improve the safety of remote site airway management...
2014: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/26556848/difficult-airway-society-2015-guidelines-for-management-of-unanticipated-difficult-intubation-in-adults
#7
COMMENT
C Frerk, V S Mitchell, A F McNarry, C Mendonca, R Bhagrath, A Patel, E P O'Sullivan, N M Woodall, I Ahmad
These guidelines provide a strategy to manage unanticipated difficulty with tracheal intubation. They are founded on published evidence. Where evidence is lacking, they have been directed by feedback from members of the Difficult Airway Society and based on expert opinion. These guidelines have been informed by advances in the understanding of crisis management; they emphasize the recognition and declaration of difficulty during airway management. A simplified, single algorithm now covers unanticipated difficulties in both routine intubation and rapid sequence induction...
December 2015: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/26057025/negeviruses-found-in-multiple-species-of-mosquitoes-from-southern-portugal-isolation-genetic-diversity-and-replication-in-insect-cell-culture
#8
Sara Carapeta, Beatriz do Bem, James McGuinness, Aida Esteves, Ana Abecasis, Ângela Lopes, António P de Matos, João Piedade, António P G de Almeida, Ricardo Parreira
In this report, an RT-PCR approach based on the use of degenerate primers allowed the identification of negeviruses in four different species of mosquitoes (Ochlerotatus caspius, Culex pipiens, Cx. theileri and Cx. univittatus) collected in southern Portugal. The genomes of two of these viruses, sequenced to full completion, were shown to encode all the proteins encoded by previously described negeviruses. One of these viruses induces exuberant cytopathic effect in insect cell culture, with no obvious signs of apoptosis induction, replicating very rapidly and allowing for the detection of viral genomes in the infected culture supernatant as soon as 4h post-infection...
September 2015: Virology
https://www.readbyqxmd.com/read/25810520/dissociation-between-the-experience-dependent-development-of-hippocampal-theta-sequences-and-single-trial-phase-precession
#9
Ting Feng, Delia Silva, David J Foster
Theta sequences are circuit-level activity patterns produced when groups of hippocampal place cells fire in sequences that reflect a compressed behavioral order of place fields within each theta cycle. The high temporal coordination between place cells exhibited in theta sequences is compatible with the induction of synaptic plasticity and has been proposed as one of the mechanisms underlying the encoding of episodic memory of recently acquired experience. Yet how theta sequences develop with experience has not been directly addressed...
March 25, 2015: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/25748118/-perioperative-management-of-a-morbidly-obese-pregnant-patient-undergoing-cesarean-section-under-general-anesthesia-case-report
#10
Márcio Luiz Benevides, Verônica Cristina Moraes Brandão, Jacqueline Ivonne Arenas Lovera
BACKGROUND AND OBJECTIVES: The increased prevalence of obesity in the general population extends to women of reproductive age. The aim of this study is to report the perioperative management of a morbidly obese pregnant woman, body mass index > 50 kg/m(2), who underwent cesarean section under general anesthesia. CASE REPORT: Pregnant woman in labor, 35 years of age, body mass index 59.8 kg/m(2). Caesarean section was indicated due to the presumed fetal macrosomia...
July 2016: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/24481137/alterations-in-the-transcriptome-of-soybean-in-response-to-enhanced-somatic-embryogenesis-promoted-by-orthologs-of-agamous-like15-and-agamous-like18
#11
Qiaolin Zheng, Sharyn E Perry
Somatic embryogenesis (SE) is a poorly understood process during which competent cells respond to inducing conditions, allowing the development of somatic embryos. It is important for the regeneration of transgenic plants, including for soybean (Glycine max). We report here that constitutive expression of soybean orthologs of the Arabidopsis (Arabidopsis thaliana) MADS box genes Agamous-like15 (GmAGL15) and GmAGL18 increased embryogenic competence of explants from these transgenic soybean plants. To understand how GmAGL15 promotes SE, expression studies were performed...
March 2014: Plant Physiology
https://www.readbyqxmd.com/read/24364010/cesarean-section-in-a-patient-with-non-compaction-cardiomyopathy-managed-with-ecmo
#12
A A Koster, F Pappalardo, S Silvetti, U Schirmer, J U Lueth, R Dummler, M Emmerich, M Schmitt, G Kirchne, D Kececioglu, E Sandica
Isolated ventricular non-compaction is a rare cardiomyopathy associated with left heart failure, severe arrhythmias and thromboembolism. We report about our interdisciplinary strategy in a patient with severe isolated ventricular non-compaction cardiomyopathy scheduled for caesarean section in general anaesthesia. Monitoring included placement of an arterial line, a central venous catheter and a pulmonary artery catheter with pacing option. Small introducer gates were placed in the femoral artery and vein to facilitate quick percutaneous institution of extracorporeal life support via extracorporeal membrane oxygenation in case of acute cardiac failure refractory to medical treatment...
2013: Heart, Lung and Vessels
https://www.readbyqxmd.com/read/24214290/concise-review-leukemia-stem-cells-in-personalized-medicine
#13
REVIEW
Monica L Guzman, John N Allan
Despite increased comprehension of acute myelogenous leukemia (AML) pathogenesis, current treatment strategies have done little to improve upon standard induction chemotherapy to induce long-term remissions. Since the identification of the leukemic stem cell, efforts have been placed on identifying therapeutically actionable pathways that distinguish this increasingly important cellular compartment. With the advent of increased genome sequencing efforts and phenotypic characterization, opportunities for personalized treatment strategies are rapidly emerging...
April 2014: Stem Cells
https://www.readbyqxmd.com/read/23945941/replication-fork-collapse-is-a-major-cause-of-the-high-mutation-frequency-at-three-base-lesion-clusters
#14
Yuliya Sedletska, J Pablo Radicella, Evelyne Sage
Unresolved repair of clustered DNA lesions can lead to the formation of deleterious double strand breaks (DSB) or to mutation induction. Here, we investigated the outcome of clusters composed of base lesions for which base excision repair enzymes have different kinetics of excision/incision. We designed multiply damaged sites (MDS) composed of a rapidly excised uracil (U) and two oxidized bases, 5-hydroxyuracil (hU) and 8-oxoguanine (oG), excised more slowly. Plasmids harboring these U-oG/hU MDS-carrying duplexes were introduced into Escherichia coli cells either wild type or deficient for DNA n-glycosylases...
November 2013: Nucleic Acids Research
https://www.readbyqxmd.com/read/23757470/gastric-tubes-and-airway-management-in-patients-at-risk-of-aspiration-history-current-concepts-and-proposal-of-an-algorithm
#15
REVIEW
M Ramez Salem, Arjang Khorasani, Siavosh Saatee, George J Crystal, Mohammad El-Orbany
Rapid sequence induction and intubation (RSII) and awake tracheal intubation are commonly used anesthetic techniques in patients at risk of pulmonary aspiration of gastric or esophageal contents. Some of these patients may have a gastric tube (GT) placed preoperatively. Currently, there are no guidelines regarding which patient should have a GT placed before anesthetic induction. Furthermore, clinicians are not in agreement as to whether to keep a GT in situ, or to partially or completely withdraw it before anesthetic induction...
March 2014: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/23634566/videolaryngoscopic-endotracheal-intubation-glidescope-of-morbidly-obese-patients-in-semi-erect-position-a-comparison-with-rapid-sequence-induction-in-supine-position
#16
RANDOMIZED CONTROLLED TRIAL
Deepak Gupta, Konstantin Rusin
BACKGROUND: In regards to peri-anesthetic morbidity considerations, morbidly obese patients often have full stomach for extended periods secondary to delayed gastric emptying. Additionally, they may have difficulty lying supine because of multiple reasons. STUDY OBJECTIVES: The purpose of the study was to compare endotracheal intubation of morbidly obese patients placed in semi-erect position with the rapid sequence induction in the supine position using GlideScope video laryngoscopy...
October 2012: Middle East Journal of Anesthesiology
https://www.readbyqxmd.com/read/23510899/comparison-of-rocuronium-and-succinylcholine-on-postintubation-sedative-and-analgesic-dosing-in-the-emergency-department
#17
COMPARATIVE STUDY
Justin D Korinek, Rachel M Thomas, Luke A Goddard, Alexander E St John, John C Sakles, Asad E Patanwala
OBJECTIVES: Rocuronium and succinylcholine are both commonly used neuromuscular blockers for rapid sequence intubation in the emergency department (ED). The objective of this study was to determine if patients who receive rocuronium are more likely to receive lower doses of postintubation sedatives and analgesics compared with patients who receive succinylcholine. METHODS: This was a retrospective cohort study carried out in a tertiary, academic ED. Consecutive adult patients, who were intubated using etomidate for induction of sedation, were included...
June 2014: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://www.readbyqxmd.com/read/21808408/failed-rapid-sequence-induction-in-an-achondroplastic-dwarf
#18
Jasleen Kaur, Padmaja Durga, Nirmala Jonnavithula, Gopinath Ramachandran
Achondroplasia, a common cause of short limbed type of dwarfism is due to quantitative decrease in rate of endochondral ossification. This abnormal bone growth leads to disproportionate body and head structure, thus placing them under high risk for anaesthetic management. There is paucity in literatures, regarding appropriate drug dosage selection in these patients. Use of drugs as per standard dosage recommendations based on body weight or body surface area, may not be adequate in these patients owing to discrepancies in overall body weight and lean body weight, especially during rapid sequence induction...
May 2011: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/21705176/-airway-management-in-obstetrics
#19
REVIEW
M Boutonnet, V Faitot, H Keïta
OBJECTIVE: Reviewing problems related to the airway management in obstetrics, taking into account the recent evolutions of the anaesthetic practices in obstetrics. DATA SOURCES: A review of the literature in English and French was performed in the Pumed database in April 2010. The first research used the following MeshTerms: "Anesthesia, Obstetrical" [Mesh] AND "Intubation, Intratracheal" [Mesh]. Complementary research used alone or in combination the following keywords: difficult tracheal intubation; failed tracheal intubation; airway; prediction of difficult tracheal intubation; maternal mortality; maternal morbidity; liability; aspiration pneumonia and obstetrical anesthesia...
September 2011: Annales Françaises D'anesthèsie et de Rèanimation
https://www.readbyqxmd.com/read/21480829/rocuronium-and-sugammadex-for-rapid-sequence-induction-of-obstetric-general-anaesthesia
#20
R M Williamson, S Mallaiah, P Barclay
BACKGROUND: Many anaesthetists use rocuronium in place of suxamethonium for rapid sequence induction (RSI). This is less common in obstetric anaesthesia as the duration of action of an effective dose of rocuronium exceeds most obstetric procedures. Sugammadex offers the possibility of rapidly reversing profound rocuronium neuromuscular blockade at the end of surgery. We aimed to determine whether rocuronium 1.2 mg/kg used for RSI in the obstetric population would provide good intubating conditions at 60 s and would be effectively reversed by sugammadex at the end of surgery...
July 2011: Acta Anaesthesiologica Scandinavica
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