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https://www.readbyqxmd.com/read/29470484/the-characteristic-of-asthma-control-among-nasal-diseases-population-results-from-a-cross-sectional-study
#1
Jiangtao Lin, Jie Gao, Kefang Lai, Xin Zhou, Bei He, Jianying Zhou, Changzheng Wang
Asthma affects a large number of patients in China, but comprehensive evaluation of risks associated with poor asthma control in asthmatic patients with nasal diseases was still limited. We conducted this study to provide a comprehensive estimate of asthma control in Chinese asthma patients with combined nasal diseases, to explore the effect of kinds of nasal diseases on the asthma control, and to identify risk factors associated with uncontrolled asthmatic patients with combined nasal diseases. 1756 asthma patients concomitant with nasal diseases aged ≥17 years and representing all regions of mainland China were surveyed...
2018: PloS One
https://www.readbyqxmd.com/read/29466477/mysinusitiscoach-patient-empowerment-in-chronic-rhinosinusitis-using-mobile-technology
#2
S F Seys, J Bousquet, C Bachert, W J Fokkens, I Agache, M Bernal-Sprekelsen, I Callebaut, L O Cardel, S Carrie, P Castelnuovo, R Cathcart, J Constantinidis, L Cools, M Cornet, G Clement, J C de Sousa, T Cox, M Doulaptsi, P Gevaert, C Hopkins, V Hox, T Hummel, W Hosemann, R Jacobs, M Jorissen, B N Landis, A Leunig, V J Lund, J Mullol, M Onerci, S Palkonen, I Proano, E Prokopakis, D Ryan, H Riechelmann, J Saevels, C Segboer, K Speleman, E A Steinsvik, P Surda, P V Tomasiz, O Vanderveken, L Van Gerven, T Van Zele, B Verhaeghe, K Vierstraete, S Vlaminck, J Wilkinson, S Williams, B Pugin, P W Hellings
Mobile health technology is emerging to take a prominent position in the management of chronic diseases. These technologies aim at enhancing patient empowerment via education and self-management. To date, of all the different apps available for patients with sinus disease, none were developed by medical experts dealing with chronic rhinosinusitis (CRS). The European Forum for Research and Education in Allergy and Airway diseases (EUFOREA) has undertaken a multi-stakeholder approach for designing, developing and implementing a tool to support CRS patients in monitoring their symptoms and to provide patients with a digital support platform containing reliable medical information about their disease and treatment options...
February 21, 2018: Rhinology
https://www.readbyqxmd.com/read/29465510/chronic-rhinosinusitis-related-to-occupational-exposure-the-telemark-population-study
#3
Ulrika K E Clarhed, Martin Svendsen, Linus Schiöler, Johny Kongerud, Kjell Torén, Johan Hellgren, Anne Kristin Fell
OBJECTIVE: To investigate the association between occupational exposure and chronic rhinosinusitis. METHODS: A random population from the region of Telemark, aged 16-50, answered a respiratory questionnaire including questions on chronic rhinosinusitis and exposure in the occupational environment. RESULTS: A total of 16,099/48,142 subjects responded. The prevalence of chronic rhinosinusitis was 9%. Exposure associated with chronic rhinosinusitis comprised paper dust (OR 1...
February 19, 2018: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29464415/inflammatory-biomarkers-during-bacterial-acute-rhinosinusitis
#4
REVIEW
Timo J Autio, Timo Koskenkorva, Petri Koivunen, Olli-Pekka Alho
PURPOSE OF REVIEW: Diagnosis of bacterial acute rhinosinusitis is difficult. Several attempts have been made to clarify the diagnostic criteria. Inflammatory biomarkers are easily obtainable variables that could shed light on both the pathophysiology and diagnosis of bacterial acute rhinosinusitis. The purpose of this review article is to assess literature concerning the course of inflammatory biomarkers during acute rhinosinusitis and the use of inflammatory biomarkers in diagnosing bacterial acute rhinosinusitis...
February 21, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29460678/a-systematic-review-of-the-association-between-cigarette-smoke-exposure-and-chronic-rhinosinusitis
#5
Dallin N Christensen, Zechariah G Franks, Hilary C McCrary, Ahlam A Saleh, And Eugene H Chang
Objectives Cigarette smoking and passive smoke exposure have been associated with chronic rhinosinusitis (CRS). Our goal in this systematic review was to (1) determine if there was a strong correlative effect in large population studies between cigarette smoke exposure and the prevalence of CRS, (2) investigate pathogenic mechanisms of cigarette smoke in the upper airway, and (3) determine if a history of cigarette smoking affects the medical and surgical outcomes of CRS. Data Sources MEDLINE, Embase, Cochrane CENTRAL, Web of Science SCI and CPCI-S, and websites...
February 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29456949/clarithromycin-in-the-management-of-chronic-rhinosinusitis-preliminary-results-of-a-possible-its-new-use
#6
F Sireci, R Speciale, S Gallina, R Sorrentino, F R Canevari
The aim of this study is to evaluate the efficacy and safety of prolonged therapy with low-dose clarithromycin in patients with chronic rhinosinusitis with polyps (CRSwP) after endoscopic sinus surgery (ESS). A total of 10 patients with CRSwP were identified and subjected to bilateral ESS. In post-operative patients they were treated with nasal wash with saline solution and steroid sprays (beclomethasone). During follow-up, after 30-40 days after the operation (M = 35.4 SD = +4.33), patients reported a worsening of symptoms with onset of nasal obstruction; reduction/loss of smell; headache; onset of viscous secretions and therefore all patients continued therapy with saline nasal irrigation, topical steroid therapy and started macrolide (clarithromycin 500 mg/pill: 1 pill/day for 3 days a week for 1 month)...
March 2018: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29456942/bacterial-biofilms-in-chronic-rhinosinusitis-and-their-implications-for-clinical-management
#7
Abhilasha Karunasagar, Santosh S Garag, Suma B Appannavar, Raghavendra D Kulkarni, Ashok S Naik
To study the microbiological profile in patients with chronic rhino-sinusitis. To correlate disease severity with the presence of biofilms and host risk factors. To assess outcome of Sinus Surgery 2 weeks post operatively in terms of presence of bacteria and their ability to form biofilm. Prospective study. 50 cases of chronic rhino-sinusitis requiring Functional Endoscopic Sinus Surgery admitted in SDM Hospital, Dharwad, Karnataka were studied using intra-operative mucosal samples for microbiological analysis...
March 2018: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29456658/expression-of-clara-cell-10-kda-protein-and-trefoil-factor-family-1-in-patients-with-chronic-rhinosinusitis-and-nasal-polyps
#8
Yuanyuan Wang, Zong-Feng Wang, Zhili Zhang, Yi Su
The current study measured the expression of Clara cell 10-kDa protein (CC10) and trefoil factor family 1 (TFF1) in the sinus mucosa of patients exhibiting chronic rhinosinusitis (CRS) and nasal polyps (NP). CC10 and TFF1 expression in the sinus mucosa of the control group and patients with CRS and NP was determined using reverse transcription-quantitative polymerase chain reaction (RT-qPCR), western blotting and immunohistochemistry. The correlation between CC10 and TFF1 expression was further analyzed using Spearman's correlation analysis...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29453018/-management-of-rhinosinusitis-in-primary-care
#9
N Gómez Gabaldón, C Manzanares Arnaiz, L Noguero Cánovas, J Juan Armas
Acute rhinosinusitis is an important health problem. Even though its frequency is not well documented in our country?, the economic burden it bears is not insignificant as it notably alters the quality of life of affected patients. Its diagnosis is generally clinical in nature, with further studies reserved only for the differential diagnoses of complications or tumour-like processes. The most frequent causes are viral infections, although Streptococcus pneumoniae and Haemophilus influenzae are the most commonly isolated bacterial agents...
February 13, 2018: Semergen
https://www.readbyqxmd.com/read/29452201/the-nasal-microbiome-in-chronic-rhinosinusitis-analyzing-the-effects-of-atopy-and-bacterial-functional-pathways-in-111-patients
#10
Mahboobeh Mahdavinia, Phillip A Engen, Phillip S LoSavio, Ankur Naqib, Rafsa J Khan, Mary C Tobin, Arpita Mehta, Raj Kota, Nailliw Preite, Christopher D Codispoti, Bobby A Tajudeen, Robert P Schleimer, Stefan J Green, Ali Keshavarzian, Pete S Batra
No abstract text is available yet for this article.
February 13, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29452200/identification-of-clinically-relevant-chronic-rhinosinusitis-endotypes-using-cluster-analysis-of-mucus-cytokines
#11
Justin H Turner, Rakesh K Chandra, Ping Li, Kemberlee Bonnet, David G Schlundt
No abstract text is available yet for this article.
February 13, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29450780/systematic-reviews-and-meta-analysis-in-rhinosinusitis-a-critical-review-of-the-reviews
#12
REVIEW
Abigail Walker, Claire Hopkins
PURPOSE OF REVIEW: There has been an explosion in the number of published systematic reviews on chronic rhinosinusitis in the last decade. RECENT FINDINGS: While the aim of these reviews in facilitating evidence-based practice is laudable, poor quality reviews may contain significant bias that can mislead a non-discerning reader. Attention therefore must be given to review methodology before implanting findings. Organisations such as the Cochrane Collaboration promote high-quality reviews, but are limited in chronic sinus disease by heterogeneous outcomes and a paucity of randomised trials...
February 16, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29450710/indicators-for-imaging-in-periorbital-cellulitis-secondary-to-rhinosinusitis
#13
Basel Jabarin, Ephraim Eviatar, Ofer Israel, Tal Marom, Haim Gavriel
PURPOSE: Our objective was to identify the clinical indicators for subperiosteal orbital abscess (SPOA) among patients who present with periorbital cellulitis secondary to rhinosinusitis, and to evaluate the need for performing a computerized tomography (CT) scan. METHODS: A retrospective cohort study of all patients admitted to our tertiary care emergency department between 2006 and 2014 was conducted. Included were healthy patients with acute periorbital cellulitis secondary to rhinosinusitis...
February 15, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29450659/social-factors-in-the-development-of-chronic-rhinosinusitis-a-systematic-review
#14
REVIEW
I Geramas, D Terzakis, E Hatzimanolis, C Georgalas
PURPOSE OF REVIEW: In an era where prevention is paramount, understanding social factors for chronic rhinosinusitis (CRS) may facilitate preventive interventions that mitigate risk factors associated with the initiation or progression of the disease. RECENT FINDINGS: Both passive and active smoking are clearly and unequivocally associated with both the incidence and the severity of rhinosinusitis, while there an increasing body of evidence linking social deprivation and low socioeconomic status with rhinosinusitis and its complications...
February 16, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29450387/orbital-cellulitis-and-brain-abscess-rare-complications-of-maxillo-spheno-ethmoidal-rhinosinusitis
#15
Farah Constantin, Patricia-Alexandra Niculescu, Oana Petre, Daniel Balasa, Alexandru Tunas, Ioana Rusu, Mihai Lupascu, Cristiana Orodel
Sinus infections can be complicated by ocular infections and, in late phases, by brain parenchyma infection. The article debates the case of a 12-year-old patient suffering from paucisymptomatic maxillo-spheno-ethmoidal rhinosinusitis, which was later complicated by orbital cellulitis, ending with the development of a brain abscess. The treatment is complex, initially targeting the source of the infection through draining the collection by middle maxillary antrostomy and anterior posterior ethmoidectomy, then the ablation of the brain abscess and postoperatively with prolonged massive antibiotherapy...
April 2017: Romanian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29449345/antimicrobial-activity-of-a-novel-bioengineered-honey-against-non-typeable-haemophilus-influenzae-biofilms-an-in-vitro-study
#16
Rachel S Newby, Matthew Dryden, Raymond N Allan, Rami J Salib
The opportunistic pathogen non-typeable Haemophilus influenzae (NTHi) plays an important role in many chronic respiratory diseases including otitis media, chronic rhinosinusitis, cystic fibrosis and chronic obstructive pulmonary disease. Biofilm formation has been implicated in NTHi colonisation, persistence of infection and recalcitrance towards antimicrobials. There is therefore a pressing need for the development of novel treatment strategies that are effective against NTHi biofilm-associated diseases. SurgihoneyRO is a honey-based product that has been bioengineered to enable the slow release of H 2 O 2 , a reactive oxygen species to which H...
February 15, 2018: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29447888/pathogenesis-of-chronic-rhinosinusitis-in-patients-affected-by-%C3%AE-thalassemia-major-and-sickle-cell-anaemia-post-allogenic-bone-marrow-transplant
#17
F Martino, R Di Mauro, K Paciaroni, J Gaziev, C Alfieri, L Greco, R Floris, S Di Girolamo, M Di Girolamo
OBJECTIVES: Sickle cell anemia (SCA) and β -thalassemia major are well-recognized beta-globin gene disorders of red blood cells associated to mortality and morbidity included bone morbidities due to ineffective erythropoiesis and bone marrow expansion, which affect every part of the skeleton. While there are an abundance of described disease manifestations of the head and neck, the manner of paranasal sinuses involvement and its relations to β-thalassemia and SCA process was not studied yet...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29445292/late-onset-asthma-current-perspectives
#18
REVIEW
Tsunahiko Hirano, Kazuto Matsunaga
Because the pathophysiology of asthma has diverse characteristics, to manage the disease effectively, it is important for clinicians to distinguish among the clinical phenotypes. Among them, adult-onset asthma, that is, late-onset asthma (LOA), is increasing because of the aging of the population. The phenotype of LOA is largely divided into two types according to the presence or absence of eosinophilic inflammation, T-helper (Th)2- and non-Th2-associated LOA. Especially in Th2 LOA related to rhinosinusitis, as pulmonary function at onset is poor and asthma exacerbations occur frequently, it is important to detect this phenotype in the early phase by using a biomarker of Th2-type inflammation such as fractional exhaled nitric oxide (FE NO )...
2018: Journal of Asthma and Allergy
https://www.readbyqxmd.com/read/29437297/snot-22-based-clusters-in-chronic-rhinosinusitis-without-nasal-polyposis-exhibit-distinct-endotypic-and-prognostic-differences
#19
Devyani Lal, Claire Hopkins, Rohit D Divekar
BACKGROUND: Endotypic and prognosticating features of chronic rhinosinusitis without nasal polyposis (CRSsNP) are poorly understood. Our objectives were to use an unbiased symptom-based approach to: (1) study symptoms, clinical and endotypic features; and (2) identify features predicating outcomes from endoscopic sinus surgery (ESS). METHODS: Clinical, computed tomography (CT), histopathology, and 22-item Sino-Nasal Outcome Test (SNOT-22) data was collected on 146 adult CRSsNP patients who underwent ESS...
February 13, 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29432969/age-related-prevalence-of-chronic-rhinosinusitis-and-nasal-polyps-and-their-relationships-with-asthma-onset
#20
Ha-Kyeong Won, Young-Chan Kim, Min-Gyu Kang, Han-Ki Park, Seung-Eun Lee, Min-Hye Kim, Min-Suk Yang, Yoon-Seok Chang, Sang-Heon Cho, Woo-Jung Song
BACKGROUND: Chronic rhinosinusitis (CRS) is a major disease condition with high morbidity, and may influence lower airway disease status in adults. However, its associations with adult asthma onset and activity have not been examined in detail in a general adult population. OBJECTIVE: To investigate the relationships between CRS with nasal polyps and asthma characteristics. METHODS: A cross-sectional dataset from 17,506 adult participants (age≥18 years) in the Korean National Health and Nutrition Examination Survey 2010-2012 was analyzed...
February 9, 2018: Annals of Allergy, Asthma & Immunology
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