Juan Fernando Ortiz, Ahmed Eissa-Garces, Samir Ruxmohan, Victor Cuenca, Mandeep Kaur, Stephanie P Fabara, Mahika Khurana, Jashank Parwani, Maria Paez, Fatima Anwar, Hyder Tamton, Wilson Cueva
Parinaud's syndrome involves dysfunction of the structures of the dorsal midbrain. We investigated the pathophysiology related to the signs and symptoms to better understand the symptoms of Parinaud's syndrome: diplopia, blurred vision, visual field defects, ptosis, squint, and ataxia, and Parinaud's main signs of upward gaze paralysis, upper eyelid retraction, convergence retraction nystagmus (CRN), and pseudo-Argyll Robertson pupils. In upward gaze palsy, three structures are disrupted: the rostral interstitial nucleus of the medial longitudinal fasciculus (riMLF), interstitial nucleus of Cajal (iNC), and the posterior commissure...
November 6, 2021: Brain Sciences