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https://www.readbyqxmd.com/read/28911857/new-mouse-model-for-inducing-and-evaluating-unilateral-vestibular-deafferentation-syndrome
#1
R Cassel, P Bordiga, D Pericat, C Hautefort, B Tighilet, C Chabbert
BACKGROUND: Unilateral vestibular deafferentation syndrome (uVDS) holds a particular place in the vestibular pathology domain. Due to its suddenness, the violence of its symptoms that often result in emergency hospitalization, and its associated original neurophysiological properties, this syndrome is a major source of questioning for the otoneurology community. Also, its putative pathogenic causes remain to be determined. There is currently a strong medical need for the development of targeted and effective countermeasures to improve the therapeutic management of uVDS...
September 11, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28911803/sensory-overload-and-imbalance-resting-state-vestibular-connectivity-in-ptsd-and-its-dissociative-subtype
#2
Sherain Harricharan, Andrew A Nicholson, Maria Densmore, Jean Théberge, Margaret C McKinnon, Richard W J Neufeld, Ruth A Lanius
BACKGROUND: The vestibular system integrates multisensory information to monitor one's bodily orientation in space, and is influenced by interoceptive awareness. Post-traumatic stress disorder (PTSD) involves typically alterations in interoceptive and bodily self-awareness evidenced by symptoms of hyperarousal, as well as of emotional detachment, including emotional numbing, depersonalization, and derealization. These alterations may disrupt vestibular multisensory integration between the brainstem (vestibular nuclei) and key vestibular cortical regions (parieto-insular vestibular cortex, prefrontal cortex)...
September 11, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28894988/how-tandem-gait-stumbled-into-the-neurological-exam-a-review
#3
Jason Margolesky, Carlos Singer
Tandem gait testing is an integral part of the neurological exam. It is informative in a wide variety of disorders ranging from cerebellar disease to vestibular and peripheral neuropathies, parkinsonism, and other neurodegenerative conditions. We discuss the history and development of tandem gait testing as well as its technique, utility, and limitations in the assessment of neurological conditions. Tandem gait has emerged as a tool in the assessment of cerebellar disease, Huntington disease, idiopathic Parkinson's disease, atypical parkinsonism, peripheral neuropathies, and vestibulopathies...
September 11, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28889981/visual-vestibular-conflict-detection-depends-on-fixation
#4
Isabelle T Garzorz, Paul R MacNeilage
Visual and vestibular signals are the primary sources of sensory information for self-motion. Conflict among these signals can be seriously debilitating, resulting in vertigo [1], inappropriate postural responses [2], and motion, simulator, or cyber sickness [3-8]. Despite this significance, the mechanisms mediating conflict detection are poorly understood. Here we model conflict detection simply as crossmodal discrimination with benchmark performance limited by variabilities of the signals being compared. In a series of psychophysical experiments conducted in a virtual reality motion simulator, we measure these variabilities and assess conflict detection relative to this benchmark...
September 4, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28885964/cervical-joint-position-sense-in-hypobaric-conditions-a-randomized-double-blind-controlled-trial
#5
Diana Bagaianu, Damien Van Tiggelen, N Duvigneaud, Veerle Stevens, Danny Schroyen, Dirk Vissenaeken, Gino D'Hondt, Laurent Pitance
Well-adapted motor actions require intact and well-integrated information from all of the sensory systems, specifically the visual, vestibular, and somatosensory systems, including proprioception. Proprioception is involved in the sensorimotor control by providing the central nervous system with an updated body schema of the biomechanical and spatial properties of the body parts. With regard to the cervical spine, proprioceptive information from joint and muscle mechanoreceptors is integrated with vestibular and visual feedback to control head position, head orientation, and whole body posture...
September 2017: Military Medicine
https://www.readbyqxmd.com/read/28885483/assessing-readability-and-reliability-of-online-patient-information-regarding-vestibular-schwannoma
#6
Harry Spiers, Nikul Amin, Raj Lakhani, Andrew J Martin, Parag M Patel
HYPOTHESIS: The aim of this study is to objectively assess the quality and readability of websites related to vestibular schwannomas. BACKGROUND: Patients are increasingly seeking information on confirmed or suspected diagnoses through the Internet. Clinicians are often concerned regarding the accuracy, quality, and readability of web-based sites. METHODS: Online information relating to vestibular schwannoma was searched using the three most popular search engines...
September 6, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28884719/-vestibular-migraine-diagnostic-difficulties-and-treatment-optimization
#7
A V Li, E V Parkhomenko, A N Barinov
AIM: The study aimed at showing actual information about vestibular migraine and presenting different features of vestibular migraine for prevention of diagnostic mistakes and choosing an effective treatment. MATERIAL AND METHODS: Fifty patients with vestibular migraine were diagnosed according to the International Classification of Headache Disorders 3rd edition and examined in a neurological department. RESULTS: Problems with outpatient diagnosis and treatment were found...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28883717/assessing-balance-through-the-use-of-a-low-cost-head-mounted-display-in-older-adults-a-pilot-study
#8
Santiago J Saldana, Anthony P Marsh, W Jack Rejeski, Jack K Haberl, Peggy Wu, Scott Rosenthal, Edward H Ip
INTRODUCTION: As the population ages, the prevention of falls is an increasingly important public health problem. Balance assessment forms an important component of fall-prevention programs for older adults. The recent development of cost-effective and highly responsive virtual reality (VR) systems means new methods of balance assessment are feasible in a clinical setting. This proof-of-concept study made use of the submillimeter tracking built into modern VR head-mounted displays (VRHMDs) to assess balance through the use of visual-vestibular conflict...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28861034/playing-music-may-improve-the-gait-pattern-in-patients-with-bilateral-caloric-areflexia-wearing-a-cochlear-implant-results-from-a-pilot-study
#9
Ann Hallemans, Griet Mertens, Paul Van de Heyning, Vincent Van Rompaey
HYPOTHESIS: Auditory information through an active cochlear implant (CI) influences gait parameters in adults with bilateral caloric areflexia and profound sensorineural hearing loss. BACKGROUND: Patients with bilateral caloric areflexia suffer from imbalance, resulting in an increased risk of falling. In case of simultaneous deafness, the lack of auditory feedback results in less awareness of the auditory scene. This combination might produce significant challenges while walking and navigating...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28861030/coding-of-velocity-storage-in-the-vestibular-nuclei
#10
Sergei B Yakushin, Theodore Raphan, Bernard Cohen
Semicircular canal afferents sense angular acceleration and output angular velocity with a short time constant of ≈4.5 s. This output is prolonged by a central integrative network, velocity storage that lengthens the time constants of eye velocity. This mechanism utilizes canal, otolith, and visual (optokinetic) information to align the axis of eye velocity toward the spatial vertical when head orientation is off-vertical axis. Previous studies indicated that vestibular-only (VO) and vestibular-pause-saccade (VPS) neurons located in the medial and superior vestibular nucleus could code all aspects of velocity storage...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28861024/gravity-cues-embedded-in-the-kinematics-of-human-motion-are-detected-in-form-from-motion-areas-of-the-visual-system-and-in-motor-related-areas
#11
Fabien Cignetti, Pierre-Yves Chabeauti, Jasmine Menant, Jean-Luc J J Anton, Christina Schmitz, Marianne Vaugoyeau, Christine Assaiante
The present study investigated the cortical areas engaged in the perception of graviceptive information embedded in biological motion (BM). To this end, functional magnetic resonance imaging was used to assess the cortical areas active during the observation of human movements performed under normogravity and microgravity (parabolic flight). Movements were defined by motion cues alone using point-light displays. We found that gravity modulated the activation of a restricted set of regions of the network subtending BM perception, including form-from-motion areas of the visual system (kinetic occipital region, lingual gyrus, cuneus) and motor-related areas (primary motor and somatosensory cortices)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28844105/the-floccular-syndrome-dynamic-changes-in-eye-movements-and-vestibulo-ocular-reflex-in-isolated-infarction-of-the-cerebellar-flocculus
#12
Dario Andres Yacovino, Manuel Perez Akly, Leonel Luis, David S Zee
The cerebellar flocculus is a critical structure involved in the control of eye movements. Both static and dynamic abnormalities of the vestibulo-ocular reflex (VOR) have been described in animals with experimental lesions of the flocculus/paraflocculus complex. In humans, lesions restricted to the flocculus are rare so they can become an exceptional model to contrast with the clinical features in experimental animals or in patients with more generalized cerebellar diseases. Here, we examined a 67-year-old patient with an acute vestibular syndrome due to an isolated infarct of the right flocculus...
August 26, 2017: Cerebellum
https://www.readbyqxmd.com/read/28838116/surgery-after-primary-radiation-treatment-for-sporadic-vestibular-schwannomas-case-series
#13
Jonathan D Breshears, Joseph A Osorio, Steven W Cheung, Igor J Barani, Philip V Theodosopoulos
BACKGROUND: As radiation has become an increasingly popular primary treatment option for sporadic vestibular schwannomas, there is a minority of tumors that do not respond favorably to radiation. Data on repeat radiosurgery are emerging, and salvage surgery has been associated with increased technical difficulty and poor facial nerve outcomes. OBJECTIVE: To review the current literature and report our results with surgical resection of sporadic vestibular schwannomas that have failed primary radiation treatment...
August 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28833469/clinicopathologic-features-and-magnetic-resonance-imaging-findings-in-24-cats-with-histopathologically-confirmed-neurologic-feline-infectious-peritonitis
#14
A H Crawford, A L Stoll, D Sanchez-Masian, A Shea, J Michaels, A R Fraser, E Beltran
BACKGROUND: Feline infectious peritonitis (FIP) is the most common infectious central nervous system (CNS) disease in the cat and is invariably fatal. Improved means of antemortem diagnosis is required to facilitate clinical decision making. Information regarding the magnetic resonance imaging (MRI) findings of neurologic FIP currently is limited, resulting in the need for better descriptions to optimize its use as a diagnostic tool. OBJECTIVE: To describe the clinicopathologic features and MRI findings in cases of confirmed neurologic FIP...
September 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28819687/central-not-peripheral-vestibular-processing-impairs-gait-coordination
#15
Yoav Gimmon, Jennifer Millar, Rebecca Pak, Elizabeth Liu, Michael C Schubert
Gait coordination is generated by neuronal inter-connections between central pattern generators in the spinal cord governed by cortical areas. Malfunction of central vestibular processing areas generates vestibular symptoms in the absence of an identifiable peripheral vestibular system lesion. Walking in the dark enforces a coordinated afference primarily from the vestibular and somatosensory systems. We hypothesized that patients with aberrant central vestibular processing would demonstrate unique gait characteristics, and have impaired gait coordination compared with those patients with abnormal peripheral vestibular function and healthy controls...
August 17, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28814635/perception-of-the-dynamic-visual-vertical-during-sinusoidal-linear-motion
#16
Antonella Pomante, Luc P J Selen, W Pieter Medendorp
The vestibular system provides information for spatial orientation. However, this information is ambiguous: because the otoliths sense the gravito-inertial force, they cannot distinguish gravitational and inertial components. As a consequence, prolonged linear acceleration of the head can be interpreted as tilt, referred to as the somatogravic effect. Previous modeling work suggests that the brain disambiguates the otolith signal according to the rules of Bayesian inference, combining noisy canal cues with the a priori assumption that prolonged linear accelerations are unlikely...
August 16, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28813962/a-fundamental-study-on-how-holding-a-helium-filled-balloon-affects-stability-in-human-standing
#17
Keisuke Shima, Koji Shimatani, Gen Sato, Mami Sakata, Psiche Giannoni, Pietro Morasso
Various studies have been conducted in the field of the development/deterioration of standing and walking ability. In standing and walking control strategy, the relationship linking visual/somatosensory/vestibular-system information and physical movement is important. Researchers have previously sought to evaluate attitude control based on human sensory information. The authors have also reported that the body sway of a walking infant is mitigated when the subject holds a helium-filled balloon, with results suggesting that this approach can be applied to extend walking distance...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28802368/study-of-the-effects-of-hearing-on-static-and-dynamic-postural-function-in-children-using-cochlear-implants
#18
Malihah Mazaheryazdi, Abdollah Moossavi, Javad Sarrafzadah, Saeed Talebian, Shohreh Jalaie
OBJECTIVE: The present study aimed to evaluate the postural control perturbations by the center of pressure parameters in two main approaches, cochlear implant turned "on" and "off". METHODS: We included 25 children aged 8-10 years with unilateral cochlear implants and bilateral vestibular hypofunction deficit. To evaluate the postural function, each children was asked to stand on the force plate under 3 different conditions and cochlear implant turned "on" and "off": Condition (A) double stance from open eyes to closed eyes, Condition (B) double stance with open eyes engaging in the dual task and Condition (C) From double leg stance to one leg stance with open eyes for assessment of dynamic postural control...
September 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28795618/distribution-of-dental-plaque-and-gingivitis-within-the-dental-arches
#19
Prem K Sreenivasan, Kakarla V V Prasad
Objective The natural accumulation of supragingival plaque on surfaces of human teeth is associated with gingival inflammation and the initiation of common oral diseases. This study evaluated the distribution of dental plaque and gingivitis scores within the dental arches after prophylaxis. Methods Adult subjects from the Dharwad, India area representing the general population who provided written informed consent were scheduled for screening. Healthy subjects over the age of 18 years, not currently requiring any medical or dental care, and presenting with a complement of at least 20 natural teeth were recruited for this parallel design study...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28794847/neuro-otological-and-peripheral-nerve-involvement-in-fabry-disease
#20
Sergio Carmona, Romina Weinschelbaum, Ana Pardal, Cintia Marchesoni, Paz Zuberbuhler, Patricia Acosta, Guillermo Cáceres, Isaac Kisinovsky, Luciana Bayón, Ricardo Reisin
Fabry disease (FD) is an X-linked lysosomal storage disease, with multisystemic glycosphingolipids deposits. Neuro-otological involvement leading to hearing loss and vestibular dysfunctions has been described, but there is limited information about the frequency, site of lesion, or the relationship with peripheral neuropathy. The aim was to evaluate the presence of auditory and vestibular symptoms, and assess neurophysiological involvement of the VIII cranial nerve, correlating these findings with clinical and neurophysiological features of peripheral neuropathy...
July 18, 2017: Audiology Research
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