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https://www.readbyqxmd.com/read/28334328/vestibular-aqueduct-midpoint-width-and-hearing-loss-in-patients-with-an-enlarged-vestibular-aqueduct
#1
Mustafa S Ascha, Nauman Manzoor, Amit Gupta, Maroun Semaan, Cliff Megerian, Todd D Otteson
Importance: Elucidating the relationship between vestibular aqueduct size and hearing loss progression may inform the prognosis and counseling of patients who have an enlarged vestibular aqueduct (EVA). Objectives: To examine the association between vestibular aqueduct size and repeated measures of hearing loss. Design, Setting, and Participants: For this retrospective medical record review, 52 patients with a diagnosis of hearing loss and radiologic diagnosis of EVA according to the Valvassori criterion were included...
March 23, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28321563/do-patients-with-m%C3%A3-ni%C3%A3-re-s-disease-have-attacks-of-syncope
#2
Ilmari Pyykkö, Vinaya Manchaiah, Jing Zou, Hilla Levo, Erna Kentala
The aim of the present study was to evaluate the prevalence and associated factors for syncope among patients with Ménière's disease (MD). An attack of syncope was defined as a sudden and transient loss of consciousness, which subsides spontaneously and without a localizing neurological deficit. The study used an across-sectional survey design. Information from a database consisting of 961 individuals was collected from the Finnish Ménière Association. The data contained case histories, general health-related quality of life (HRQoL), and impact measurements of the complaints...
March 20, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28321373/a-review-of-skull-base-tumor-clinical-trials-past-trends-and-future-opportunities
#3
Anand Devaiah, Charles Murchison
Objective Tumors of the anterior and lateral skull base (TALSB) are relatively rare but can be devastating to patients. By examining trials focused on TALSB, we can characterize the studies that predominate and better understand current directions of study. This gives us a better understanding of future studies to pursue. Study Design This is a retrospective analysis. Settings We set skull base tumor clinical trials in the United States which are listed in ClinicalTrials.gov. Subjects and Methods We used the information available on ClinicalTrials...
April 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28291459/clinical-and-magnetic-resonance-spectroscopic-imaging-findings-in-veterans-with-blast-mild-traumatic-brain-injury-and-post-traumatic-stress-disorder
#4
Anthony P Kontos, Anne C Van Cott, Jodilyn Roberts, Jullie W Pan, Monique B Kelly, Jamie McAllister-Deitrick, Hoby P Hetherington
OBJECTIVES: To compare magnetic resonance spectroscopic imaging (MRSI) findings from the hippocampal regions of military veterans with blast-related mild traumatic brain injury (blast mTBI) and post-traumatic stress disorder (PTSD) to those with PTSD only; and to examine the relationship of MRSI findings to cognitive and neuromotor impairment. METHODS: 35 military veterans-23 with blast mTBI and PTSD (blast mTBI/PTSD) and 12 with PTSD only participated in the study...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28277209/importance-of-an-interprofessional-team-approach-in-achieving-improved-management-of-the-dizzy-patient
#5
Amanda I Rodriguez, Steven Zupancic, Michael M Song, Joehassin Cordero, Tam Q Nguyen, Charles Seifert
BACKGROUND: Because of its multifaceted nature, dizziness is difficult for clinicians to diagnose and manage independently. Current treatment trends suggest that patients are often referred to the otolaryngologist for intervention despite having a nonotologic disorder. Additionally, many individuals with atypical presentations are often misdiagnosed and spend a significant amount of time waiting for consultation by the otolaryngologist. Few studies have alluded that implementation of an interprofessional team approach in the diagnosis and management of the dizzy patient can improve clinical decision-making...
March 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28265687/activation-of-the-thalamic-parafascicular-nucleus-by-electrical-stimulation-of-the-peripheral-vestibular-nerve-in-rats
#6
Nari Kim, Myoung Ae Choi, Ho Koo, Byung Rim Park, Sang Who Han, Chaejoon Cheong, Min Sun Kim
The parafascicular nucleus (PFN) of the thalamus is a primary structure in the feedback circuit of the basal ganglia-thalamo-cortical system, as well as in the neural circuit of the vestibulo-thalamo-striatal pathway. We investigated the characteristics of the functional connectivity between the peripheral vestibular system and the PFN in rats. A single electrical stimulation was applied to the horizontal semicircular canal nerve in the peripheral vestibular end-organs. This resulted in polysynaptic local field potentials (LFPs) in the PFN, which were composed of long-lasting multiple waves...
March 6, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28259770/a-prospective-investigation-of-changes-in-the-sensorimotor-system-following-sports-concussion-an-exploratory-study
#7
Julie A Hides, Melinda M Franettovich Smith, M Dilani Mendis, Nigel A Smith, Andrew J Cooper, Julia Treleaven, Felix Leung, Andrew J Gardner, Paul McCrory, Nancy L Low Choy
BACKGROUND: Sports concussion is a risk for players involved in high impact, collision sports. Post-concussion, the majority of symptoms subside within 7-10 days, but can persist in 10-20% of athletes. Understanding the effects of sports concussion on sensorimotor systems could inform physiotherapy treatment. OBJECTIVE: To explore changes in sensorimotor function in the acute phase following sports concussion. DESIGN: Prospective cohort study...
February 24, 2017: Musculoskelet Sci Pract
https://www.readbyqxmd.com/read/28256416/the-triage-score-for-vertigo-or-dizziness-a-diagnostic-model-for-stroke-in-the-emergency-department
#8
R Kuroda, T Nakada, T Ojima, M Serizawa, N Imai, N Yagi, A Tasaki, M Aoki, T Oiwa, T Ogane, K Mochizuki, M Kobari, H Miyajima
BACKGROUND: Vertigo or dizziness is a common occurrence, but it remains a challenging symptom when encountered in the emergency department (ED). A diagnostic score for stroke with high accuracy is therefore required. METHODS: A single-center observational study (498 patients) was conducted. The predictor variables were derived from a multivariate logistic regression analysis with Akaike information criterion. The outcome was the occurrence of stroke. We evaluated the utility of a new diagnostic score (TriAGe+) and compared it with the ABCD2 score...
February 27, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28252629/-diagnosis-and-treatment-of-benign-paroxysmal-positional-vertigo-in-common-clinical-practice
#9
N V Lebedeva, M V Zamergrad, V A Parfenov, L M Antonenko
AIM: To analyze typical medical practice in managing patients with benign paroxysmal positional vertigo (BPPV). SUBJECTS AND METHODS: 33 patients (5 men and 28 women; mean age, 58 years) with BPPV who had been referred for consultation to the Medical Diagnostic Department, Clinic of Nervous Diseases, I.M. Sechenov First Moscow State Medical University, regarding for vertigo, were examined. Information about the disease before visiting the clinic, such as the duration of vertigo, its pattern, and triggers, previously established diagnoses, prescribed treatment and its efficacy, concomitant diseases, was analyzed...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28245927/motion-sickness-increases-functional-connectivity-between-visual-motion-and-nausea-associated-brain-regions
#10
Nicola Toschi, Jieun Kim, Roberta Sclocco, Andrea Duggento, Riccardo Barbieri, Braden Kuo, Vitaly Napadow
The brain networks supporting nausea not yet understood. We previously found that while visual stimulation activated primary (V1) and extrastriate visual cortices (MT+/V5, coding for visual motion), increasing nausea was associated with increasing sustained activation in several brain areas, with significant co-activation for anterior insula (aIns) and mid-cingulate (MCC) cortices. Here, we hypothesized that motion sickness also alters functional connectivity between visual motion and previously identified nausea-processing brain regions...
January 2017: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/28242733/ocular-stability-and-set-point-adaptation
#11
REVIEW
D S Zee, P Jareonsettasin, R J Leigh
A fundamental challenge to the brain is how to prevent intrusive movements when quiet is needed. Unwanted limb movements such as tremor impair fine motor control and unwanted eye drifts such as nystagmus impair vision. A stable platform is also necessary to launch accurate movements. Accordingly, nature has designed control systems with agonist (excitation) and antagonist (inhibition) muscle pairs functioning in push-pull, around a steady level of balanced tonic activity, the set-point Sensory information can be organized similarly, as in the vestibulo-ocular reflex, which generates eye movements that compensate for head movements...
April 19, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28230177/storage-of-passive-motion-pattern-in-hippocampal-ca1-region-depends-on-camkii-creb-signaling-pathway-in-a-motion-sickness-rodent-model
#12
Junqin Wang, Jiluo Liu, Leilei Pan, Ruirui Qi, Peng Liu, Wei Zhou, Yiling Cai
Sensory mismatch between actual motion information and anticipated sensory patterns (internal model) is the etiology of motion sickness (MS). Some evidence supports that hippocampus might involve the neural storage of the "internal model". This study established an "internal model" acquisition-retention behavioral model using a repeated habituation rotation training protocol. We tried to identify the hippocampal subregion involved in "internal model" retention using chemical lesion methods. Hippocampal kinases (CaMK, CaMKIV, CREB and ERK1/2) phosphorylation in the target subregion was assayed and the effects of kinase inhibitors (KN93 or U0126) on "internal model" retention were investigated...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28217106/effect-of-noisy-galvanic-vestibular-stimulation-on-ocular-vestibular-evoked-myogenic-potentials-to-bone-conducted-vibration
#13
Shinichi Iwasaki, Shotaro Karino, Teru Kamogashira, Fumiharu Togo, Chisato Fujimoto, Yoshiharu Yamamoto, Tatsuya Yamasoba
OBJECTIVE: Galvanic vestibular stimulation (GVS) delivered as zero-mean current noise (noisy GVS) has been shown to improve static and dynamic postural stability probably by enhancing vestibular information. The purpose of this study was to examine the effect of an imperceptible level noisy GVS on ocular vestibular-evoked myogenic potentials (oVEMPs) in response to bone-conducted vibration (BCV). MATERIALS AND METHODS: oVEMPs to BCV were measured during the application of white noise GVS with an amplitude ranging from 0 to 300 µA [in root mean square (RMS)] in 20 healthy subjects...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28197672/functional-near-infrared-spectroscopy-fnirs-brain-imaging-of-multi-sensory-integration-during-computerized-dynamic-posturography-in-middle-aged-and-older-adults
#14
Chia-Cheng Lin, Jeffrey W Barker, Patrick J Sparto, Joseph M Furman, Theodore J Huppert
Studies suggest that aging affects the sensory re-weighting process, but the neuroimaging evidence is minimal. Functional Near-Infrared Spectroscopy (fNIRS) is a novel neuroimaging tool that can detect brain activities during dynamic movement condition. In this study, fNIRS was used to investigate the hemodynamic changes in the frontal-lateral, temporal-parietal, and occipital regions of interest (ROIs) during four sensory integration conditions that manipulated visual and somatosensory feedback in 15 middle-aged and 15 older adults...
April 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28194100/head-stability-and-head-trunk-coordination-in-horseback-riders-the-contribution-of-visual-information-according-to-expertise
#15
Agnès Olivier, Elise Faugloire, Laure Lejeune, Sophie Biau, Brice Isableu
Maintaining equilibrium while riding a horse is a challenging task that involves complex sensorimotor processes. We evaluated the relative contribution of visual information (static or dynamic) to horseback riders' postural stability (measured from the variability of segment position in space) and the coordination modes they adopted to regulate balance according to their level of expertise. Riders' perceptual typologies and their possible relation to postural stability were also assessed. Our main assumption was that the contribution of visual information to postural control would be reduced among expert riders in favor of vestibular and somesthetic reliance...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28184173/reliability-of-inertial-sensors-in-the-assessment-of-patients-with-vestibular-disorders-a-feasibility-study
#16
Sathish K Sankarpandi, Alice J Baldwin, Jaydip Ray, Claudia Mazzà
BACKGROUND: Vestibular disorders affect an individual's stability, balance, and gait and predispose them to falls. Traditional laboratory-based semi-objective vestibular assessments are intrusive and cumbersome provide little information about their functional ability. Commercially available wearable inertial sensors allow us to make this real life assessments objective, with a detailed view of their functional abilities. Timed Up and Go (TUG) and Postural Sway tests are commonly used tests for gait and balance assessments...
2017: BMC Ear, Nose, and Throat Disorders
https://www.readbyqxmd.com/read/28179477/perceptual-precision-of-passive-body-tilt-is-consistent-with-statistically-optimal-cue-integration
#17
Koeun Lim, Faisal Karmali, Keyvan Nicoucar, Daniel M Merfeld
When making perceptual decisions, humans have been shown to optimally integrate independent noisy multisensory information - matching maximum likelihood (ML) limits. Such ML estimators provide a theoretic limit to perceptual precision (i.e., minimal thresholds). However, how the brain combines two interacting (i.e., not independent) sensory cues remains an open question. To study the precision achieved when combining interacting sensory signals, we measured perceptual roll tilt and roll rotation thresholds between 0 and 5Hz in 6 normal human subjects...
February 8, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28176264/the-integration-of-neural-information-by-a-passive-kinetic-stimulus-and-galvanic-vestibular-stimulation-in-the-lateral-vestibular-nucleus
#18
Gyutae Kim, Kyu-Sung Kim, Sangmin Lee
Despite an easy control and the direct effects on vestibular neurons, the clinical applications of galvanic vestibular stimulation (GVS) have been restricted because of its unclear activities as input. On the other hand, some critical conclusions have been made in the peripheral and the central processing of neural information by kinetic stimuli with different motion frequencies. Nevertheless, it is still elusive how the neural responses to simultaneous GVS and kinetic stimulus are modified during transmission and integration at the central vestibular area...
February 7, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28163007/vestibular-contributions-to-high-level-sensorimotor-functions
#19
W Pieter Medendorp, Luc J P Selen
The vestibular system, which detects motion and orientation of the head in space, is known to be important in controlling gaze to stabilize vision, to ensure postural stability and to provide our sense of self-motion. While the brain's computations underlying these functions are extensively studied, the role of the vestibular system in higher level sensorimotor functions is less clear. This review covers new research on the vestibular influence on perceptual judgments, motor decisions, and the ability to learn multiple motor actions...
February 2, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28157577/sensory-reweighting-after-loss-of-auditory-cues-in-healthy-adults
#20
Maxime Maheu, Andréanne Sharp, Simon P Landry, François Champoux
We maintain our balance using information provided by the visual, somatosensory, and vestibular systems on the position of our body in space. Recent evidence has suggested that auditory input also plays a significant role for postural control, yet further investigations are required to better understand the contributions of audition to this process in healthy adults. To date, the process of sensory reweighting when auditory cues are disturbed during postural control has been overlooked. The aim of this study is to determine the impact of hearing protection on sensory reweighting for postural control in healthy adults...
January 24, 2017: Gait & Posture
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