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Danning Xu, Bingxin Li, Nan Cao, Wanyan Li, Yunbo Tian, Yunmao Huang
Heat stress can cause immune organ dysfunction and apoptosis. Polysaccharide of Atractylodes macrocephala Koidz may have protective effects on immune organs. In this study, we established chicken models of Polysaccharide of Atractylodes macrocephala Koidz-heat stress interaction and detected the oxidative index, activities of mitochondrial complexes and ATPases as well as the ultrastructure in chicken spleens. Expression levels of cytokines, mitochondrial dynamics- and apoptosis-related genes were also measured...
September 19, 2017: Oncotarget
Nobuyasu Kato, Masaaki Yamagishi, Keiichi Itatani, Takako Miyazaki, Yoshinobu Maeda, Satoshi Asada, Yoshiro Matsui, Hitoshi Yaku
OBJECTIVES: To clarify the risk factors for abnormal degeneration of autologous pericardium, the mechanical stress on the endothelial tissue caused by turbulent blood flow in the pulmonary artery (PA) reconstructed with autologous pericardium and major aortopulmonary collateral arteries was assumed in pulmonary atresia and ventricular septal defect. METHODS: Patient-specific PA models were created for 6 patients based on their past computed tomography images taken after unifocalization of major aortopulmonary collateral arteries...
October 12, 2017: Interactive Cardiovascular and Thoracic Surgery
Jacqueline Heckenhauer, Kamariah Abu Salim, Mark W Chase, Kyle G Dexter, R Toby Pennington, Sylvester Tan, Maria Ellen Kaye, Rosabelle Samuel
DNA barcoding is a fast and reliable tool to assess and monitor biodiversity and, via community phylogenetics, to investigate ecological and evolutionary processes that may be responsible for the community structure of forests. In this study, DNA barcodes for the two widely used plastid coding regions rbcL and matK are used to contribute to identification of morphologically undetermined individuals, as well as to investigate phylogenetic structure of tree communities in 70 subplots (10 × 10m) of a 25-ha forest-dynamics plot in Brunei (Borneo, Southeast Asia)...
2017: PloS One
Earric Lee, Tanjaniina Laukkanen, Setor K Kunutsor, Hassan Khan, Peter Willeit, Francesco Zaccardi, Jari A Laukkanen
Background Heat therapy has been suggested to improve cardiovascular function. However, the effects of hot sauna exposure on arterial compliance and the dynamics of blood flow and pressure have not been well documented. Thus, we investigated the short-term effects of sauna bathing on arterial stiffness and haemodynamics. Design The design was an experimental non-randomised study. Methods There were 102 asymptomatic participants (mean age, 51.9 years) who had at least one cardiovascular risk factor. Participants were exposed to a single sauna session (duration: 30 min; temperature: 73℃; humidity: 10-20%)...
January 1, 2017: European Journal of Preventive Cardiology
Jinying Li, Ke Chen, Qi Peng, Zhongke Wang, Yang Jiang, Chengyu Fu, Ge Ren
Risley prisms appear to be a promising solution to high-accuracy pointing and tracking. To improve the pointing accuracy of achromatic Risley prisms, an appropriate mathematical model is established, and the forward and inverse solutions are proposed. Focusing on the sources of systematic errors, an optimization method based on a genetic algorithm is proposed to identify the parameters of the physical model, including wedge angles, refractive indexes, and installations. Finally, the experimental platform is established...
September 10, 2017: Applied Optics
Haiyu Meng, Lingling Wang, Guidong Liu, Xiongxiong Xue, Qi Lin, Xiang Zhai
We numerically investigate the optical performance of a periodically patterned H-shaped graphene array by the finite-difference time-domain (FDTD) in the mid-infrared region. The simulated results reveal that absorption spectra of the proposed structure consist of two dramatic narrowband perfect absorption peaks located at 6.3 μm (Mode 1) and 8.6 μm (Mode 2) with high absorption coefficients of 99.65% and 99.80%, respectively. Two impressive absorption bandwidths that are the full width at half-maximum (FWHM) of the resonant frequency of 90 nm and 188 nm are obtained...
July 20, 2017: Applied Optics
Liangjin Huang, Tianfu Yao, Jinyong Leng, Shaofeng Guo, Rumao Tao, Pu Zhou, Xiang'ai Cheng
The study on mode instability (MI) in the large-mode-area fiber is generating great interest regarding the high-power applications of fiber lasers. To the best of our knowledge, we have investigated for the first time the dynamics of the output beam from a kilowatt-level all-fiber amplifier based on the low-numerical-aperture (<0.04) step-index (SI) fiber before and after the onset of the MI, including the temporal dynamics and mode evolution. The temporal power fluctuations indicate three evolution stages apart from the onset threshold of the MI, defined as stable, transition, and chaotic regions...
July 1, 2017: Applied Optics
Maki S Koyama, Silvia Ortiz-Mantilla, Cynthia P Roesler, Michael P Milham, April A Benasich
A growing literature on resting-state fMRI (R-fMRI) has explored the impact of preceding sensory experience on intrinsic functional connectivity (iFC). However, it remains largely unknown how passive exposure to irrelevant auditory stimuli, which is a constant in everyday life, reconfigures iFC. Here, we directly compared pre- and post-exposure R-fMRI scans to examine: 1) modulatory effects of brief passive exposure to repeating non-linguistic sounds on subsequent iFC, and 2) associations between iFC modulations and cognitive abilities...
October 17, 2017: Cerebral Cortex
Nikolaus Johannes Wachter, Martin Mentzel, Gert D Krischak, Joachim Gülke
STUDY DESIGN: A within-subject research design was used in this study. The difference of the range of motion (ROM) with and without ulnar nerve block was analyzed. INTRODUCTION: For the clinical evaluation of the functional effects of ulnar nerve palsy at the hand the relevance of clinical tests is in discussion. PURPOSE OF THE STUDY: The aim of the study was to evaluate the predictive value of 2 clinical tests for a simulated ulnar nerve lesion by motion analysis with a sensor glove...
October 14, 2017: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
Y N Efimova, A V Lichikaki, B Y Lishmanov
PURPOSE: To study the effect of radiofrequency ablation of renal arteries on regional cerebral blood flow and cognitive function in patients with resistant arterial hypertension (AH). MATERIAL AND METHODS: Transcatheter renal denervation (TRD) was performed in 17 patients with resistant AH. Examination before and after TRD included SPECT with mTc-HMPAO, 24-hours blood pressure (BP) monitoring, and comprehensive neuropsychological testing. Fifteen patients without angiographic signs of carotid atherosclerosis, coronary artery disease and AH, neurological and psychiatric disorders were investigated as control group...
July 2017: Kardiologiia
Tian Zhang, Jian Dai, Yitang Dai, Yuting Fan, Xu Han, Jianqiang Li, Feifei Yin, Yue Zhou, Kun Xu
The dynamically tunable plasmon induced absorption (PIA) effect is demonstrated in a graphene-assisted metallodielectric grating structure. Two methods are employed to achieve the tunable PIA effect in the mid-infrared region: one is based on controlling the chemical potential of graphene by adjusting the gate voltage, the other is related to varying the refractive index of interlayer. Our calculated results reveal that high tunability in amplitude and bandwidth of the PIA effect can be achieved by using the above-mentioned methods...
October 16, 2017: Optics Express
Dayane Priscila Vrisman, Natália Marins Bastos, Guilherme Fazan Rossi, Naiara Nantes Rodrigues, Luisa Pucci Bueno Borges, Augusto Ryonosuke Taira, Cláudia Cristina Paro de Paz, Guilherme de Paula Nogueira, Pedro Paulo Maia Teixeira, Fábio Morato Monteiro, Maria Emília Franco Oliveira
The objectives of this study were 1) to monitor corpus luteum (CL) dynamics after two different protocols of ovulation induction in prepubertal Nellore heifers, and 2) to determine differences in luteal function. Fifty-seven heifers (weight 289.61 ± 32.28 kg, BCS 5.66 ± 0.65, age 17.47 ± 0.81 months) were divided into two groups: GP4+GnRH received a progesterone (P4) device of 3rd use for 10 days, followed by the administration of 0.02 mg buserelin acetate (GnRH) 48 h after removal of the device, and GGnRH received only GnRH...
October 13, 2017: Theriogenology
Stacey E Aaron, Catherine J VanDerwerker, Aaron E Embry, Jennifer H Newton, Samuel C K Lee, Chris M Gregory
PURPOSE: After a cerebrovascular accident (CVA) aerobic deconditioning contributes to diminished physical function. Functional Electrical Stimulation (FES)-assisted cycling is a promising exercise paradigm designed to target both aerobic capacity and locomotor function. This pilot study aimed to evaluate the effects of an FES-assisted cycling intervention on aerobic capacity and locomotor function in individuals post-CVA. METHODS: Eleven individuals with chronic (> 6 months) post-CVA hemiparesis completed an 8-week (3x/wk; 24 sessions) progressive FES-assisted cycling intervention...
October 16, 2017: Medicine and Science in Sports and Exercise
Yang Li, Liang Song, Jinyan Lin, Zhou Pan, Jinyuan Ma, Yinying Zhang, Guanghao Su, Shefang Ye, Fang-Hong Luo, Xuan Zhu, Zhenqing Hou
Tumor-targeting combination chemotherapy is an important way to improve the therapeutic index and reduce the side effects compared to traditional cancer treatments. However, one of the major challenges in surface functionalization of nanoparticle (NP) is accomplishing multiple purposes through one single ligand. Upon such consideration, methotrexate (MTX), an anticancer drug with a targeting moiety inspired by the similar structure of folate, could be used to covalently link with lipid-polymer conjugate (DSPE-PEG) via pH-sensitive dynamic covalent imine (CH=N) bond to synthesize the acid-induced function "Targeting-Anticancer" switching DSPE-PEG-CH=N-MTX...
October 17, 2017: ACS Applied Materials & Interfaces
I Ortiz, M Urbano, J Dorado, J M Morrell, E Al-Essawe, A Johannisson, M Hidalgo
The aim of this study was to compare sperm DNA fragmentation of frozen-thawed epididymal sperm of dogs using the SCSA (Sperm Chromatin Structure Assay) and SCDt (Sperm Chromatin Dispersion test). For this purpose, epididymis from neutered dogs were minced and incubated in a Tris-based extender. The recovered sperm were frozen in a two-step cooling protocol with Tris-based, egg yolk extender and increasing glycerol concentrations, and stored in liquid nitrogen. After thawing, each replica was incubated at 38°C for 24h...
October 12, 2017: Animal Reproduction Science
Srikara V Peelukhana, Rupak K Banerjee, Tim P van de Hoef, Kranthi K Kolli, Mohamed Effat, Tarek Helmy, Massoud Leesar, Hanan Kerr, Jan J Piek, Paul Succop, Lloyd Back, Imran Arif
BACKGROUND: In this study, lesion flow coefficient (LFC: ratio of % area stenosis [%AS] to the square root of the ratio of the pressure drop across the stenosis to the dynamic pressure in the throat region), that combines both the anatomical (%AS) and functional measurements (pressure and flow), was assessed for application in a clinical setting. METHODS AND RESULTS: Pressure, flow, and anatomical values were obtained from patients in 251 vessels from two different centers...
September 11, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
P Y Khan, A C Crampin, T Mzembe, O Koole, K L Fielding, K Kranzer, J R Glynn
BACKGROUND: Understanding of the effects of human immunodeficiency virus (HIV) infection and antiretroviral treatment (ART) on Mycobacterium tuberculosis transmission dynamics remains limited. We undertook a cross-sectional study among household contacts of smear-positive pulmonary tuberculosis (TB) cases to assess the effect of established ART on the infectiousness of TB. METHOD: Prevalence of tuberculin skin test (TST) positivity was compared between contacts of index cases aged 2-10 years who were HIV-negative, HIV-positive but not on ART, on ART for <1 year and on ART for 1 year...
November 1, 2017: International Journal of Tuberculosis and Lung Disease
Ignacio Faustino, S J Marrink
Summary: We introduce cgHeliParm, a python program that provides the conformational analysis of Martini-based coarse-grained double strand DNA molecules. The software calculates the helical parameters such as base, base pair and base pair step parameters. cgHeliParm can be used for the analysis of coarse grain Martini molecular dynamics trajectories without transformation into atomistic models. Availability and implementation: This package works with Python 2.7 on MacOS and Linux...
July 13, 2017: Bioinformatics
Pi Guo, Tao Liu, Qin Zhang, Li Wang, Jianpeng Xiao, Qingying Zhang, Ganfeng Luo, Zhihao Li, Jianfeng He, Yonghui Zhang, Wenjun Ma
BACKGROUND: In China, dengue remains an important public health issue with expanded areas and increased incidence recently. Accurate and timely forecasts of dengue incidence in China are still lacking. We aimed to use the state-of-the-art machine learning algorithms to develop an accurate predictive model of dengue. METHODOLOGY/PRINCIPAL FINDINGS: Weekly dengue cases, Baidu search queries and climate factors (mean temperature, relative humidity and rainfall) during 2011-2014 in Guangdong were gathered...
October 16, 2017: PLoS Neglected Tropical Diseases
Zahra Vali, Asghar Gholami, Zabih Ghassemlooy, David G Michelson, Masood Omoomi, Hamed Noori
Turbulence affects the performance of underwater wireless optical communications (UWOC). Although multiple scattering and absorption have been previously investigated by means of physical simulation models, still a physical simulation model is needed for UWOC with turbulence. In this paper, we propose a Monte Carlo simulation model for UWOC in turbulent oceanic clear water, which is far less computationally intensive than approaches based on computational fluid dynamics. The model is based on the variation of refractive index in a horizontal link...
July 1, 2017: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
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