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Formula milk

Elizabeth A Brownell, Adam P Matson, Kelsey C Smith, James E Moore, Patricia A Esposito, Mary M Lussier, Trudy J Lerer, James I Hagadorn
BACKGROUND: A dose-response relationship between proportions of donor human milk (DHM) intake and in-neonatal intensive care unit (in-NICU) growth rates, if any, remains poorly defined. Objective was to evaluate interrelationships between percentages of DHM, mother's own milk (MOM), and preterm formula (PF) intake and neonatal growth parameters at 36 weeks postmenstrual age or NICU discharge. METHODS: Infants eligible for this single-center retrospective study were inborn at ≤32 weeks gestation or ≤1800 g, stayed in the NICU for ≥7 days, and received enteral nutrition consisting of human milk fortified with Enfamil human milk fortifier acidified liquid...
March 14, 2018: Journal of Pediatric Gastroenterology and Nutrition
Jacqueline H Wolf
In the late 19th-century United States and Europe, infants died at high rates from diarrhea. Physicians and social justice advocates responded to the public health crisis with attempts to clean up the water and cows' milk supplies, as well as social welfare legislation and assorted educational efforts to help mothers better care for their children. Most visible among the educational efforts were breastfeeding campaigns. A century later in developing countries, physicians and activists were confronted with a similar problem-infants dying from diarrhea due to the unethical advertising and marketing practices of formula companies...
March 1, 2018: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
Laura Morlacchi, Paola Roggero, Maria Lorella Giannì, Beatrice Bracco, Debora Porri, Enrico Battiato, Camilla Menis, Nadia Liotto, Domenica Mallardi, Fabio Mosca
Background: Nutritional management of preterm infants aims to approximate the tissue growth and body composition of a fetus of the same postmenstrual age. The adequacy of the quality of protein supply can influence the rate and the relative quality of weight gain. Objective: We investigated the protein balance according to feeding regimen and the association between human milk feeding and fat-free mass content at the term-corrected age in very-low-birth-weight preterm infants...
February 1, 2018: American Journal of Clinical Nutrition
Xue Li, Jun Cao, Xinpeng Bai, Zefang Jiang, Xuanri Shen
Human milk fat substitutes (HMFS) are rich in polyunsaturated fatty acids which upon microencapsulation, can be used as a source of high quality lipids in infant formula. The response surface methodology (RSM) was employed to optimize the microencapsulation condition of HMFS as a functional product. The microencapsulation efficiency (MEE) of microencapsulated HMFS was investigated with respect to four variables including concentration of soy lecithin (A), ratio of demineralized whey powder to malt dextrin (B), HFMS concentration (C), and homogenizing pressure (D)...
March 9, 2018: Journal of Oleo Science
Ce Qi, Jin Sun, Yuan Xia, Renqiang Yu, Wei Wei, Jingying Xiang, Qingzhe Jin, Hang Xiao, Xingguo Wang
Fatty acid (FA) is the major energy resource in breast milk, which is important for infant development. FAs profiles with sn-2 positional preference were an important part of triacylglycerols due to their better availability. This profile is still not replicated in artificial formulas. This study quantified the FAs profile of total and sn-2 position in human breast milk samples from 103 healthy volunteers during colostrum, transitional, and mature stages. Multicomponent analysis showed significant differences in FAs profiles of different lactation periods, due to that with relative percentage less than 1%...
March 15, 2018: Journal of Agricultural and Food Chemistry
Siying Liu, Yunyun Geng, Libing Liu, Xiaoxia Sun, Jingyu Shao, Beibei Han, Jianchang Wang, Ke Tan
Cronobacter spp. is an opportunistic pathogen that is associated with rare but life-threatening neonatal infections resulting from the consumption of contaminated powdered infant formula milk (PIF). In the present study, we developed recombinase polymerase amplification (RPA) and real-time RPA for the detection of Cronobacter spp. in PIF for the first time by targeting the ompA gene. The specificity and sensitivity of the RPA and real-time RPA were validated and the practical applicability of these methods for the detection of Cronobacter spp...
March 7, 2018: Journal of Dairy Science
Javier Molina-Infante, Alfredo J Lucendo
Eosinophilic esophagitis (EoE) is a chronic, immune-mediated, esophageal disease triggered predominantly, but not excusively, by food antigens. Presently, available food allergy tests are suboptimal to predict food triggers for EoE, especially in adults. Elemental diet (exclusive feeding with aminoacid-based formulas) and empiric six-food elimination diet (6-FED; withdrawing milk, wheat, egg, soy, nuts and fish/seafood for 6 weeks), have consistently shown the best efficacy rates. However, their high level of restriction and need for multiple endoscopies have hampered their implementation in clinical practice...
March 6, 2018: Journal of Allergy and Clinical Immunology
Rachel Jane Scantlebury, Alison Moody, Oyinlola Oyebode, Jennifer Susan Mindell
BACKGROUND: Healthy Start (HS) is a UK government programme, introduced in 2006, providing vouchers to pregnant women or families with children aged <4 who are in receipt of certain benefits. Vouchers can be exchanged for fruit and vegetables (F&V), milk or infant formula. We sought to identify any association between HS and F&V intake. METHODS: We analysed repeated cross-sectional data from the Health Survey for England. Study participants were classified into one of four groups: one HS-eligible group and three control groups, meeting only the income or demographic or no eligibility criterion...
March 7, 2018: Journal of Epidemiology and Community Health
F P Martins-Celini, W A Gonçalves-Ferri, D C Aragon, J P Bernichi, C Calixto, E M F Sacramento, M A Santos, F E Martinez
The ideal feeding for premature babies has been the source of extensive debate. The aim of this study was to assess the association between type of feeding at discharge and the nutritional status of very low birth weight infants. This was a retrospective cohort of preterm babies with birth weight ≤1500 g, born between January 2006 and December 2013. The infants were divided into 3 groups according to type of feeding at discharge: exclusive breast milk (group 1), mixed feeding (group 2) and exclusive artificial formula (group 3)...
January 23, 2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
Margaret A Adgent, David M Umbach, Babette S Zemel, Andrea Kelly, Joan I Schall, Eileen G Ford, Kerry James, Kassa Darge, Julianne C Botelho, Hubert W Vesper, Donald Walt Chandler, Jon M Nakamoto, Walter J Rogan, Virginia A Stallings
Purpose: Chemicals with hormone-like activity, such as estrogenic isoflavones, may perturb human development. Infants exclusively fed soy-based formula are highly exposed to isoflavones, but their physiologic responses remain uncharacterized. Here, we compare estrogen-responsive postnatal development in infants exclusively fed soy formula, cow-milk formula and breast milk. Methods: We enrolled 410 infants born in Philadelphia area hospitals, 2010-2013; 283 infants were exclusively fed soy formula (n=102), cow-milk formula (n=111), or breast milk (n=70) throughout the study (birth to 28 [boys] or 36 [girls] weeks)...
March 1, 2018: Journal of Clinical Endocrinology and Metabolism
Pantea Nazeri, Hosein Dalili, Yadollah Mehrabi, Mehdi Hedayati, Parvin Mirmiran, Fereidoun Azizi
Despite substantial progress in the global elimination of iodine deficiency, lactating mothers and their infants remain susceptible to insufficient iodine intake. This cross-sectional study was conducted to compare iodine statuses of breast-fed and formula-fed infants and their mothers at four randomly selected health care centres in Tehran. Healthy infants <3 months old and their mothers were randomly selected for inclusion in this study. Iodine was measured in urine and breast milk samples from each infant and mother as well as commercially available infant formula...
March 5, 2018: British Journal of Nutrition
Roberta Barachetti, Elisabetta Villa, Mario Barbarini
The introduction of solid food is necessary for any infant in order to provide adequate nutrition because when they grow up milk is insufficient for their nutritional needs. Infants born preterm have increased nutritional requirements. The high nutrient demands as well as the organ immaturity of preterm infants combine to render it difficult to achieve dietary intakes that will allow preterm infants to match their in utero growth rates. Current guidelines for the introduction of solid food to term infants cannot be directly translated to preterm infants...
December 22, 2017: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
Elisabetta Villa, Roberta Barachetti, Mario Barbarini
Preterm infants are at risk for poor growth while in the Neonatal Intensive Care Unit (NICU) and after discharge from the NICU. The main objective is to reach the body composition and rate of growth of a normal fetus/infant of the same post-menstrual age during the first entire year of life. In case of human milk, the limited data do not provide convincing evidence that feeding preterm infants after discharge with multi-nutrient fortified human milk, compared with unfortified, affects important outcomes including growth rates during infancy...
December 22, 2017: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
Jacopo La Nasa, Ilaria Degano, Leonardo Brandolini, Francesca Modugno, Ilaria Bonaduce
We propose a new analytical method using reverse phase High performance liquid chromatography (HPLC) coupled through an electrospray source with a tandem quadrupole-time-of-flight (ESI-Q-ToF) mass spectrometric detector for the full characterization and quantitation of the different classes of fatty acids and acylglycerols in lipid samples in a single chromatographic run. In this work, we optimized the derivatization reaction for free fatty acids with 2-hydrazinoquinoline, which is a low-cost approach, using a full factorial design...
July 12, 2018: Analytica Chimica Acta
Liang Jie, Ce Qi, Jin Sun, Renqiang Yu, Xiangyu Wang, Sameh A Korma, Jingying Xiang, Qingzhe Jin, Casimir C Akoh, Hang Xiao, Xingguo Wang
Breast milk consumption reduces the incidence of necrotizing enterocolitis (NEC) in preterm infants compared to formula. Branched-chain fatty acids (BCFAs) are present in breast milk but not in most formulas intended for preterm infants. We aimed to determine the composition of BCFAs in the breast milk of mothers with preterm infants, and to understand the impact of gestational age at birth and stage of lactation on BCFA content. The main BCFAs in preterm breast milk were iso-14:0, iso-15:0, anteiso-15:0, iso-16:0, iso-17:0, and anteiso-17:0...
March 2, 2018: Food & Function
Javier Calvo, Nadia Raquel García Lara, María Gormaz, Manuela Peña, María José Martínez Lorenzo, Pilar Ortiz Murillo, Josep Maria Brull Sabaté, Carmen María Samaniego, Antoni Gayà
It is widely agreed that the best source of nutrition for the newborn is the milk of their own mothers. In those cases where it is not available, especially in very premature and/or very low birth weight infants, as well as other sick newborns, the preferred choice before formula is the human milk provided by selected donors. This indication is supported by the highest international bodies dedicated to the health of the child population, including the World Health Organisation as well as the main national and international scientific societies in the field of Paediatrics...
February 26, 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
Bozena Kociszewska-Najman, Natalia Mazanowska, Bronislawa Pietrzak, Leszek Paczek, Monika Szpotanska-Sikorska, Joanna Schreiber-Zamora, Ewa Hryniewiecka, Dorota Zochowska, Emilia Samborowska, Michal Dadlez, Miroslaw Wielgos
Currently, the majority of neonates born to organ recipient mothers on chronic immunosuppressive therapy are formula fed. However, over the past few years, evidence has grown, suggesting that breastfeeding might be possible and beneficial. We designed a study assessing the transfer of tacrolimus into the colostrum of posttransplant mothers. We assessed the amount of tacrolimus and its metabolites, M-1 and M-3, that would be ingested by the breastfed neonates. Concentrations of tacrolimus and its metabolites were measured in colostrum from 14 posttransplant mothers as well as in venous cord blood and venous blood of the neonates...
February 27, 2018: Nutrients
Susan Trang, John A F Zupancic, Sharon Unger, Alex Kiss, Nicole Bando, Sabrina Wong, Sharyn Gibbins, Deborah L O'Connor
OBJECTIVES: To determine the cost-effectiveness of supplemental donor human milk (DHM) versus preterm formula (PTF) for very low birth weight (VLBW, <1500 g) infants from a societal perspective to 18 months' corrected age. METHODS: This prospective cost-effectiveness analysis of 363 VLBW infants was conducted for a randomized control trial. Infants recruited from October 2010 to December 2012 were fed DHM or PTF whenever mother's milk was unavailable. Formal health care costs for initial hospitalization and readmissions were obtained from standardized cost-accounting systems and physician fees...
February 28, 2018: Pediatrics
Zahoor Ul Hassan, Roda Al Thani, Fathy A Atia, Saeed Al Meer, Quirico Migheli, Samir Jaoua
The present study was conducted to explore the occurrence of mycotoxins in commercial baby foods in Doha-Qatar. LCMS/MS- and HPLC-based analysis of baby food (n=67) for 12 mycotoxins, confirmed the presence of aflatoxin M1 (AFM1, 33%), ochratoxin A (OTA, 31%), deoxynivalenol (DON, 27%), aflatoxin B1 (AFB1, 22%), fumonisin B2 (FB2, 10%), zearalenone (ZEN, 4%) and T-2 toxin (2%). Noodles exhibited the maximum contamination percentage, with 33% of the samples being contaminated above the EU maximum limits, for at least one mycotoxin...
February 28, 2018: Food Additives & Contaminants. Part B, Surveillance
Shyam R Joshi, J Andrew Bird
No abstract text is available yet for this article.
February 23, 2018: Annals of Allergy, Asthma & Immunology
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