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https://www.readbyqxmd.com/read/28759300/par-1-and-par-2-expression-is-enhanced-in-inflamed-odontoblast-cells
#1
M M P Alvarez, G E Moura, M F M Machado, G M Viana, C A de Souza Costa, L Tjäderhane, H B Nader, I L S Tersariol, F D Nascimento
Protease-activated receptors (PARs) are G protein-coupled receptors, which are activated by proteolytical cleavage of the amino-terminus and act as sensors for extracellular proteases. We hypothesized that PAR-1 and PAR-2 can be modulated by inflammatory stimulus in human dental pulp cells. PAR-1 and PAR-2 gene expression in human pulp tissue and MDPC-23 cells were analyzed by quantitative polymerase chain reaction. Monoclonal PAR-1 and PAR-2 antibodies were used to investigate the cellular expression of these receptors using Western blot, flow cytometry, and confocal microscopy in MDPC-23 cells...
July 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28721995/comparative-evaluation-of-laser-microtextured-implant-versus-machined-collar-implant-for-soft-and-hard-tissue-attachment-a-clinical-and-radiological-study
#2
Saroj Kumar Rath, Manab Kosala, Ankit Gupta
BACKGROUND: Various mechanical modifications in the collar region of endosseous implants is a challenge for better performance and osseointegration. Here is a comparative evaluation being carried out to find out the effect of the machined collar (MC) and Laser-Lok (LL)-modified titanium implants on the success of implants being commonly advocated in partially edentulous among serving personnel and their families. MATERIALS AND METHODS: Twenty-four patients with appropriate inclusion and exclusion criteria were selected for placement of Biohorizons MC and LL implants in 12 cases each...
May 2017: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/28709940/investigation-of-l-leucine-in-reducing-the-moisture-induced-deterioration-of-spray-dried-salbutamol-sulfate-power-for-inhalation
#3
Liang Li, Sharon Shui Yee Leung, Thomas Gengenbach, Jiaqi Yu, Ge Fiona Gao, Patricia Tang, Qi Tony Zhou, Hak-Kim Chan
The aim of this study was to investigate the ability of L-leucine (LL) in preventing moisture-induced deterioration in the in vitro aerosolization performance of spray-dried (SD) salbutamol sulfate (SS). Increasing mass fraction of LL (5-80%) were co-spray dried with SS, and the physicochemical properties of the powders were characterized by laser diffraction, X-ray powder diffraction (XRD) and dynamic vapour sorption (DVS). Furthermore, the surface morphology and chemistry of fine particles was analyzed by scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS)...
July 11, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28555272/anatomical-variants-and-bilateral-lacrimal-pathways-surgery-avoiding-unnecessary-surgery
#4
Alberto Raposo, Francisco García-Purriños, Francisco Piqueras, María Ll Martínez-Martinez, Jerónimo Lajara
Success rates (SR) of transcanalicular diode laser-assisted dacryocystorhinostomy (TCL DCR) may be affected by the presence of nasal anatomical variations and additionally by whether or not the pathology is bilateral. The aim is to determine whether it is necessary to perform preliminary nasal anatomical variations surgery and to determine whether bilateral cases may be operated simultaneously. We extracted the patients undergoing simultaneous bilateral TCL DCR and we compared SR across the different groups using ANOVA, Chi-square testing and logistical regression...
August 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28492152/effect-of-stone-composition-on-the-outcomes-of-semi-rigid-ureteroscopy-using-holmium-yttrium-aluminum-garnet-laser-or-pneumatic-lithotripsy
#5
Mustafa Kadihasanoglu, Ugur Yucetas, Mehmet Gokhan Culha, Erkan Erkan, Mahmut Gokhan Toktas
OBJECTIVE: To compare the effectiveness of laser lithotripsy (LL) and pneumatic lithotripters (PL) in calcium oxalate (CaOx) and calcium phosphate (CaP) stones and assess whether these stone compositions affect the outcomes of LL and PL. STUDY DESIGN: Comparative, descriptive study. PLACE AND DURATION OF STUDY: Istanbul Training and Research Hospital, Turkey, from August 2010 to August 2015. METHODOLOGY: A total of 114 patients underwent ureteroscopy using LL and PL...
April 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28383430/timing-of-surgical-ligation-and-morbidities-in-very-low-birth-weight-infants
#6
COMPARATIVE STUDY
YoungAh Youn, Cheong-Jun Moon, Jae-Young Lee, Cheul Lee, In Kyung Sung
The present study examined whether early patent ductus arteriosus (PDA) surgical ligation at ≤2 weeks of life was associated with increased morbidities and mortality in very low birth weight infants (VLBWIs) who were diagnosed with hemodynamically significant (hs) PDA. Between December 2013 and December 2015, a total of 407 VLBWIs were admitted, of whom 145 (35.6%) infants were diagnosed with an hs PDA. The clinical data for these infants were retrospectively collected for analysis. Among the 145 VLBWIs with an hs PDA, 58 (40%) infants had surgical ligation for PDA; of these, 29 (50%) infants had early ligation (EL; ligation at ≤2 weeks of life) and 29 (50%) infants had late ligation (LL; ligation at ≥2 weeks of life)...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28271355/to-dust-or-not-to-dust-a-systematic-review-of-ureteroscopic-laser-lithotripsy-techniques
#7
REVIEW
Javier E Santiago, Adam B Hollander, Samit D Soni, Richard E Link, Wesley A Mayer
PURPOSE OF REVIEW: This review discusses factors affecting outcomes during ureteroscopy (URS) with laser lithotripsy (LL), explores specific clinical challenges to the efficacy of URS LL, and reviews the available literature comparing the dusting and basketing approaches to URS LL. RECENT FINDINGS: Data show high stone-free rates with URS LL in all locations of the urinary tract and with all stone types and sizes. Recent data comparing LL with dusting versus basketing suggest higher rates of residual fragments with dusting but less utilization of ureteral access sheaths and potentially shorter operative times...
April 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28198883/angle-resolved-coherent-wave-mixing-using-a-4%C3%A2-%C3%A2-fs-ultra-broad-bandwidth-laser
#8
I P Mercer, T Witting, T Driver, R J Cogdell, J P Marangos, J W G Tisch
We demonstrate angle-resolved coherent (ARC) wave mixing using 4 fs light pulses derived from a laser source that spans 550-1000 nm. We believe this to be the shortest pulse duration used to date in coherent multi-dimensional spectroscopy. The marriage of this ultra-broad band, few-cycle coherent source with the ARC technique will permit new investigations of the interplay between energy transfers and quantum superposition states spanning 8200  cm<sup>-1</sup>. We applied this configuration to measurements on the photosynthetic low light (LL) complex from Rhodopseudomonas palustris in solution at ambient temperature...
February 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28174421/streptomyces-euryhalinus-sp-nov-a-new-actinomycete-isolated-from-a-mangrove-forest
#9
Kaushik Biswas, Jayanta D Choudhury, Riddhi Mahansaria, Malay Saha, Joydeep Mukherjee
A Gram-positive, aerobic, non-motile actinomycete (strain MS 3/20(T)) was isolated from the sediment of the Sundarbans mangrove forest in India. On International Streptomyces Project (ISP) medium 2, the isolate produced yellowish brown to red aerial hyphae that carried spiny-surfaced spores in a retinaculum-apertum arrangement. Whole-cell hydrolysate of the strain contained LL-diaminopimelic acid and galactose. Predominant menaquinones were MK-9(H8) and MK-9(H6). Diagnostic polar lipids were glycolipid, phosphatidylglycerol, phosphatidylethanolamine, phosphatidylcholine, unidentified phospholipid and unidentified amino lipid...
June 2017: Journal of Antibiotics
https://www.readbyqxmd.com/read/28005786/the-comparison-of-the-efficacy-of-blue-light-emitting-diode-light-and-980-nm-low-level-laser-light-on-bone-regeneration
#10
COMPARATIVE STUDY
Ömür Dereci, Alper Sindel, Havva Serap Toru, Esra Yüce, Sinan Ay, Sinan Tozoğlu
The aim of this study is to histologically compare effects of blue light-emitting diode (LED) light (400-490 nm) and Ga-Al-As low-level diode laser light (980 nm) on bone regeneration of calvarial critical-sized defects in rats. Thirty Wistar Albino rats were included in the study. The experimental groups were as follows: blue LED light (400-490 nm) group (LED); 980-nm low-level laser light group (LL); and no-treatment, control group (CL). A critical-sized defect of 8 mm was formed on calvaria of rats...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27955693/three-dimensional-surface-and-ultrasound-imaging-for-daily-igrt-of-prostate-cancer
#11
Marco Krengli, Gianfranco Loi, Carla Pisani, Debora Beldì, Giuseppina Apicella, Valentina Amisano, Marco Brambilla
BACKGROUND: Image guided radiotherapy (IGRT) is an essential pre-requisite for delivering high precision radiotherapy. We compared daily variation detected by two non-ionizing imaging modalities (surface imaging and trans-abdominal ultrasound, US) to verify prostate patient setup and internal organ variations. METHODS: Forty patients with organ confined prostate cancer and candidates to curative radiotherapy were enrolled in this prospective study. At each treatment session, after laser alignment, all patients received imaging by a 3D-surface and a 3D-US system...
December 13, 2016: Radiation Oncology
https://www.readbyqxmd.com/read/27832188/melatonin-receptor-agonists-as-the-perioceutics-agents-for-periodontal-disease-through-modulation-of-porphyromonas-gingivalis-virulence-and-inflammatory-response
#12
Wei Zhou, Xuan Zhang, Cai-Lian Zhu, Zhi-Yan He, Jing-Ping Liang, Zhong-Chen Song
AIM: "Perioceutics" including antimicrobial therapy and host modulatory therapy has emerged as a vital adjunctive treatment of periodontal disease. Melatonin level was significantly reduced in patients with periodontal diseases suggesting melatonin could be applied as a potential "perioceutics" treatment of periodontal diseases. This study aims to investigate the effects of melatonin receptor agonists (melatonin and ramelteon) on Porphyromonas gingivalis virulence and Porphyromonas gingivalis-derived lipopolysaccharide (Pg-LPS)-induced inflammation...
2016: PloS One
https://www.readbyqxmd.com/read/27828176/86-internal-differential-efficiency-from-8-to-9-%C3%A2%C2%B5m-emitting-step-taper-active-region-quantum-cascade-lasers
#13
Jeremy D Kirch, Chun-Chieh Chang, Colin Boyle, Luke J Mawst, Don Lindberg, Tom Earles, Dan Botez
8.4 μm-emitting quantum cascade lasers (QCLs) have been designed to have, right from threshold, both carrier-leakage suppression and miniband-like carrier extraction. The slope-efficiency characteristic temperature T<sub>1</sub>, the signature of carrier-leakage suppression, is found to be 665 K. Resonant-tunneling carrier extraction from both the lower laser level (ll) and the level below it, coupled with highly effective ll-depopulation provide a very short ll lifetime (~0.12 ps). As a result the laser-transition differential efficiency reaches 89%, and the internal differential efficiency η<sub>id</sub>, derived from a variable mirror-loss study, is found to be 86%, in good agreement with theory...
October 17, 2016: Optics Express
https://www.readbyqxmd.com/read/27612183/design-and-performance-of-a-large-lumen-glaucoma-drainage-device
#14
J L Olson, S Groman-Lupa
PurposeWe report the in vivo testing of a large-lumen glaucoma drainage (LL-GDD) device equipped with a flow regulator. The device's membrane can be non-invasively opened with laser in the postoperative period to adjust aqueous flow and intraocular pressure.MethodsThe initial LL-GDD prototypes were constructed using 22 G silicone angiocatheters cut down to size. A 10 nm PVDF membrane was then affixed to the end using cyanoacrylate. The LL-GDD was tested first in a model eye equipped with ports for infusion and pressure measurement and in New Zealand rabbits...
January 2017: Eye
https://www.readbyqxmd.com/read/27583785/laser-lithotripsy-in-the-treatment-of-renal-stones-in-children-a-single-center-experience
#15
Predrag Ilic, Miroslav Djordjevic, Vladimir Kojovic, Slobodan Dzambasanovic
AIM: To evaluate the effectiveness and safety of laser lithotripsy in the treatment of renal stones in children in a single center. MATERIAL AND METHODS: We retrospectively analysed patients (n=36) who were treated with laser nephrolithotripsy (LL group) between 2011 and 2014. We compared those results with results of pneumatic nephrolithotripsy in patients (n=32) who were treated from 2007 to 2011 (PL group). The patients were evaluated in respect of gender, age, stone location, stone size, complications and stone-free rate...
July 22, 2016: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/27505176/comparison-of-holmium-yag-laser-and-pneumatic-lithotripsy-in-the-treatment-of-ureteral-stones-an-update-meta-analysis
#16
Shulian Chen, Liang Zhou, Tangqiang Wei, Deyi Luo, Tao Jin, Hong Li, Kunjie Wang
PURPOSE: Holmium YAG laser lithotripsy (LL) and pneumatic lithotripsy (PL) are the most commonly used procedures in the treatment of ureteral calculi. In a previous meta-analysis examining the treatment effect of the 2 modalities, the authors highlighted the need for large sample size and high quality trials to provide more uncovered outcome. Recently, several randomized controlled trials (RCTs) evaluating the same issue with larger patient number and more complicated data have been published...
2017: Urologia Internationalis
https://www.readbyqxmd.com/read/27315464/light-emitting-diodes-downregulate-cathelicidin-kallikrein-and-toll-like-receptor-2-expressions-in-keratinocytes-and-rosacea-like-mouse-skin
#17
Jee-Bum Lee, Soo Hyeon Bae, Ki Rang Moon, Eui Young Na, Sook Jung Yun, Seung-Chul Lee
Cathelicidin (LL-37), Toll-like receptor 2 (TLR-2) and kallikreins (KLKs) are key inflammatory mediators in rosacea. Laser or light-based devices have been successfully used for rosacea. We investigated the effects of light-emitting diodes (LEDs) on LL-37, KLKs, TLR-2 and protease activity in cultured normal human epidermal keratinocytes (NHEKs) and rosacea-like mouse skin (RLMS). LL-37, KLK5, KLK7 and vitamin D receptor were induced by 1α, 25-dihydroxyvitamin D3 (VD3 ) and TLR-2 by Ad-CMV transfection in cultured NHEKs...
December 2016: Experimental Dermatology
https://www.readbyqxmd.com/read/27144017/influence-of-septal-deviation-on-the-prognosis-of-transcanalicular-diode-laser-assisted-dacryocystorhinostomy
#18
Alberto Raposo, Francisco Piqueras, Francisco García-Purriños, María Ll Martínez-Martinez, Jerónimo Lajara
Purpose. The objective of the present study is to determine whether the success rate in transcanalicular diode laser-assisted dacryocystorhinostomy (TCL DCR) is influenced by the variant septal deviation (SD). Methods. Patients were divided into two groups: one including operated lacrimal pathways (LP) with no anatomical nasosinusal variants and the other group of LP with SD. This study began on January 1, 2008, and ended on December 31, 2010, at Morales Meseguer Hospital. Variables were compared by means of ANOVA and a logistic regression model (LOGIT)...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27105906/comparative-study-among-three-different-phototherapy-protocols-to-treat-chemotherapy-induced-oral-mucositis-in-hamsters
#19
Luana Campos, Érika P Cruz, Filipi S Pereira, Victor E Arana-Chavez, Alyne Simões
In this study, clinical, biochemical and histological analysis were used to compare different phototherapies, including LED, low and high-power laser (HPL) for the treatment of chemotherapy (CT)-induced oral mucositis (OM). One-hundred-fifty hamsters were divided into five groups: C: control; CH: CT/OM induction; L: CT/OM induction and treatment with LED (635 nm, 1.2 J), HL: CT/OM induction and treatment with HPL (808 nm, 10 J), LL: CT/OM induction and treatment with low-level laser therapy (LLLT) (660 nm, 1...
December 2016: Journal of Biophotonics
https://www.readbyqxmd.com/read/27100803/guidelines-for-clinical-management-of-laser-etched-laser-lok-abutments-in-two-different-clinical-scenarios-a-preclinical-laboratory-soft-tissue-assessment-study
#20
Rodrigo Neiva, Nick Tovar, Ryo Jimbo, Luiz F Gil, Paula Goldberg, Joao Pm Barbosa, Thomas Lilin, Paulo G Coelho
One-stage implants were placed in the mandibles of eight beagle dogs with laser-etched (LL) and machined abutments. After 4 weeks, half of the LL abutments were disconnected and reconnected after 10 minutes of saline storage, and the other half were replaced with a new LL abutment (impression simulation) with or without sulcus de-epithelialization. After abutment change, systems remained in vivo for 3 weeks. Results showed that LL abutments can be reconnected and that sulcus scoring prior to LL placement of one-stage implants receiving machined abutments may be beneficial...
May 2016: International Journal of Periodontics & Restorative Dentistry
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