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LL laser

J L Olson, S Groman-Lupa
PurposeWe report the in vivo testing of a large-lumen glaucoma drainage (LL-GDD) device equipped with a flow regulator. The device's membrane can be non-invasively opened with laser in the postoperative period to adjust aqueous flow and intraocular pressure.MethodsThe initial LL-GDD prototypes were constructed using 22 G silicone angiocatheters cut down to size. A 10 nm PVDF membrane was then affixed to the end using cyanoacrylate. The LL-GDD was tested first in a model eye equipped with ports for infusion and pressure measurement and in New Zealand rabbits...
September 9, 2016: Eye
Predrag Ilic, Miroslav Djordjevic, Vladimir Kojovic, Slobodan Dzambasanovic
AIM: To evaluate the effectiveness and safety of laser lithotripsy in the treatment of renal stones in children in a single center. MATERIAL AND METHODS: We retrospectively analysed patients (n=36) who were treated with laser nephrolithotripsy (LL group) between 2011 and 2014. We compared those results with results of pneumatic nephrolithotripsy in patients (n=32) who were treated from 2007 to 2011 (PL group). The patients were evaluated in respect of gender, age, stone location, stone size, complications and stone-free rate...
July 22, 2016: Annali Italiani di Chirurgia
Shulian Chen, Liang Zhou, Tangqiang Wei, Deyi Luo, Tao Jin, Hong Li, Kunjie Wang
PURPOSE: Holmium YAG laser lithotripsy (LL) and pneumatic lithotripsy (PL) are the most commonly used procedures in the treatment of ureteral calculi. In a previous meta-analysis examining the treatment effect of the 2 modalities, the authors highlighted the need for large sample size and high quality trials to provide more uncovered outcome. Recently, several randomized controlled trials (RCTs) evaluating the same issue with larger patient number and more complicated data have been published...
August 10, 2016: Urologia Internationalis
Jee-Bum Lee, Soo Hyeon Bae, Ki Rang Moon, Eui Young Na, Sook Jung Yun, Seung-Chul Lee
BACKGROUND: Cathelicidin (LL-37), Toll-like receptor 2 (TLR 2), and kallikreins (KLKs) are key inflammatory mediators in rosacea. Laser or light-based devices have been successfully used for rosacea. OBJECTIVE: We investigated the effects of light-emitting diodes (LED) on LL-37, KLKs, TLR 2, and protease activity in cultured normal human epidermal keratinocytes(NHEKs) and rosacea-like mouse skin(RLMS). METHODS: LL-37, KLK 5, KLK 7, and vitamin D receptor were induced by 1α,25-dihydroxyvitaminD3 (VD3 ) and TLR 2 by Ad-CMV transfection in cultured NHEKs...
June 17, 2016: Experimental Dermatology
Alberto Raposo, Francisco Piqueras, Francisco García-Purriños, María Ll Martínez-Martinez, Jerónimo Lajara
Purpose. The objective of the present study is to determine whether the success rate in transcanalicular diode laser-assisted dacryocystorhinostomy (TCL DCR) is influenced by the variant septal deviation (SD). Methods. Patients were divided into two groups: one including operated lacrimal pathways (LP) with no anatomical nasosinusal variants and the other group of LP with SD. This study began on January 1, 2008, and ended on December 31, 2010, at Morales Meseguer Hospital. Variables were compared by means of ANOVA and a logistic regression model (LOGIT)...
2016: Journal of Ophthalmology
Luana Campos, Érika P Cruz, Filipi S Pereira, Victor E Arana-Chavez, Alyne Simões
In this study, clinical, biochemical and histological analysis were used to compare different phototherapies, including LED, low and high-power laser (HPL) for the treatment of chemotherapy (CT)-induced oral mucositis (OM). One-hundred-fifty hamsters were divided into five groups: C: control; CH: CT/OM induction; L: CT/OM induction and treatment with LED (635 nm, 1.2 J), HL: CT/OM induction and treatment with HPL (808 nm, 10 J), LL: CT/OM induction and treatment with low-level laser therapy (LLLT) (660 nm, 1...
April 23, 2016: Journal of Biophotonics
Rodrigo Neiva, Nick Tovar, Ryo Jimbo, Luiz F Gil, Paula Goldberg, Joao Pm Barbosa, Thomas Lilin, Paulo G Coelho
One-stage implants were placed in the mandibles of eight beagle dogs with laser-etched (LL) and machined abutments. After 4 weeks, half of the LL abutments were disconnected and reconnected after 10 minutes of saline storage, and the other half were replaced with a new LL abutment (impression simulation) with or without sulcus de-epithelialization. After abutment change, systems remained in vivo for 3 weeks. Results showed that LL abutments can be reconnected and that sulcus scoring prior to LL placement of one-stage implants receiving machined abutments may be beneficial...
May 2016: International Journal of Periodontics & Restorative Dentistry
Liang Li, Siping Sun, Thaigarajan Parumasivam, John A Denman, Thomas Gengenbach, Patricia Tang, Shirui Mao, Hak-Kim Chan
L-Leucine (LL) has been widely used to enhance the dispersion performance of powders for inhalation. LL can also protect powders against moisture, but this effect is much less studied. The aim of this study was to investigate whether LL could prevent moisture-induced deterioration in in vitro aerosolization performances of highly hygroscopic spray-dried powders. Disodium cromoglycate (DSCG) was chosen as a model drug and different amounts of LL (2-40% w/w) were added to the formulation, with the aim to explore the relationship between powder dispersion, moisture protection and physicochemical properties of the powders...
May 2016: European Journal of Pharmaceutics and Biopharmaceutics
Suryaprakash Bhandari, Rajesh Bathini, Atul Sharma, Amit Maydeo
BACKGROUND AND AIMS: ERCP is an established technique for the management of bile duct stones. Large bile duct stones (>1.2 cm) require additional techniques such as mechanical lithotripsy and balloon sphincteroplasty for ductal clearance. The literature on endoscopic management of cystic duct stones (CDSs) and Mirizzi syndrome (MS) is limited. We report our experience with cholangioscopy-assisted extraction of CDSs and MS in patients in whom conventional endoscopic and surgical techniques failed...
July 2016: Gastrointestinal Endoscopy
Yuan-Yuan Kong, Yi Chen, Rui Shen, Qian-Zhou Jiang, Min-Le Chen
PURPOSE: To evaluate the long-term influence of the shear bond strength (SBS) on glass-ionomer cement (GIC) to Er:YAG-irradiated and bur-prepared enamel. MATERIALS AND METHODS: One hundred and ninety human premolar and molars were selected and the crowns were sectioned. Samples were divided into five groups, according to surface treatments: bur preparation (B); bur preparation, etching with 37% phosphoric acid (BA); laser preparation (L); laser preparation, etching with 37% phosphoric acid (LA); laser preparation, twice irradiating with laser at low (150 mJ, 10 Hz; water spray 10 ml/min) (LL)...
December 10, 2015: Lasers in Surgery and Medicine
Suryaprakash Bhandari, Amit Maydeo
BACKGROUND: Majority of the bile duct stones (BDS) are radiolucent (RL) and are amenable to conventional endoscopic extraction techniques. There is no publication that specifically discusses the optimal management of radio-opaque (RO) BDS and makes a distinction from the strategy followed for RL BDS. METHODS: Data of patients with BDS managed endoscopically from January 2009 till June 2015 were retrospectively reviewed. Diagnosis of RO stone was established during initial fluoroscopy, just prior to obtaining a cholangiogram...
November 2015: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
Renzo Guarnieri, Maurizio Grande, Stefano Ippoliti, Vincenzo Iorio-Siciliano, Francesco Riccitiello, Davide Farronato
The purpose of the present prospective randomized study was to evaluate the influence of Laser-Lok microtextured surface on soft tissue peri-implant parameters and esthetics around immediate, functionally loaded implants for single-tooth replacement in the esthetic zone. This study included 77 patients divided into two groups based on different implants used: the control group had BioHorizons tapered internal non-Laser-Lok-type implants (NLL; n = 39) and the test group had BioHorizons tapered internal Laser-Lok-type implants (LL; n = 39)...
November 2015: International Journal of Periodontics & Restorative Dentistry
Ekrem Akdeniz, Lokman İrkılata, Hüseyin Cihan Demirel, Acun Saylık, Mustafa Suat Bolat, Necmettin Şahinkaya, Mehmet Zengin, Mustafa Kemal Atilla
OBJECTIVE: We aimed to compare the effectiveness of holmium YAG laser and pneumatic lithotripsy in the treatment of ureteral stones. MATERIAL AND METHODS: A total of 216 patients who had established indications of ureteroscopy between November 2011 and June 2012 were included in this study. Patients' files were retrospectively reviewed by dividing cases as groups that underwent pneumatic (PL) or laser lithotripsy (LL) procedures. Age, sex, stone burden and localization, duration of follow-up, operative times were evaluated...
September 2014: Turkish Journal of Urology
Wei-Kang Wu, Anastasios Georgiadis, David A Copland, Sidath Liyanage, Ulrich F O Luhmann, Scott J Robbie, Jian Liu, Jiahui Wu, James W Bainbridge, David O Bates, Robin R Ali, Lindsay B Nicholson, Andrew D Dick
One of the main drivers for neovascularization in age-related macular degeneration is activation of innate immunity in the presence of macrophages. Here, we demonstrate that T helper cell type 2 cytokines and, in particular, IL-4 condition human and murine monocyte phenotype toward Arg-1(+), and their subsequent behavior limits angiogenesis by increasing soluble fms-like tyrosine kinase 1 (sFlt-1) gene expression. We document that T helper cell type 2 cytokine-conditioned murine macrophages neutralize vascular endothelial growth factor-mediated endothelial cell proliferation (human umbilical vein endothelial cell and choroidal vasculature) in a sFlt-1-dependent manner...
August 2015: American Journal of Pathology
Yong Ran, Gabriela Z Ladd, Carolina Ceballos-Diaz, Joo In Jung, Doron Greenbaum, Kevin M Felsenstein, Todd E Golde
The signal peptide peptidases (SPPs) are biomedically important proteases implicated as therapeutic targets for hepatitis C (human SPP, (hSPP)), plasmodium (Plasmodium SPP (pSPP)), and B-cell immunomodulation and neoplasia (signal peptide peptidase like 2a, (SPPL2a)). To date, no drug-like, selective inhibitors have been reported. We use a recombinant substrate based on the amino-terminus of BRI2 fused to amyloid β 1-25 (Aβ1-25) (FBA) to develop facile, cost-effective SPP/SPPL protease assays. Co-transfection of expression plasmids expressing the FBA substrate with SPP/SPPLs were conducted to evaluate cleavage, which was monitored by ELISA, Western Blot and immunoprecipitation/MALDI-TOF Mass spectrometry (IP/MS)...
2015: PloS One
Augustin R Attwell, Sandeep Patel, Michel Kahaleh, Isaac L Raijman, Roy Yen, Raj J Shah
BACKGROUND: In patients with chronic pancreatitis, laser lithotripsy (LL) permits stone fragmentation and removal during ERCP with some advantages over extracorporeal shock-wave lithotripsy (ESWL) and surgery. OBJECTIVES: To evaluate the technical success of LL in pancreatic duct (PD) stones. DESIGN: Retrospective cohort. SETTING: Four tertiary referral centers. PATIENTS: Patients undergoing endotherapy for PD stones...
August 2015: Gastrointestinal Endoscopy
Scott N Dean, Callee Walsh, Haddon Goodman, Monique L van Hoek
Pseudomonas aeruginosa and Staphylococcus aureus are ubiquitous pathogens often found together in polymicrobial, biofilm-associated infections. This study is the first to use laser ablation electrospray ionization mass spectrometry (LAESI-MS) to rapidly study bacteria within a mixed biofilm. Fast, direct, non-invasive LAESI-MS analysis of biofilm could significantly accelerate biofilm studies and provide previously unavailable information on both biofilm composition and the effects of antibiofilm treatment...
2015: Biofouling
A Burcu Altan, A Altug Bicakci, H Ilhan Mutaf, Mahmut Ozkut, V Sevinc Inan
The aim of this study was to evaluate the preventive and/or reparative effects of low-level laser therapy (LLLT) on orthodontically induced inflammatory root resorption (OIIRR) in rats. Thirty rats were divided into four groups (short-term control (SC), short-term laser (SL), long-term control (LC), long-term laser (LL)). In all groups, the left first molar was moved mesially for 11 days. At the end of this period, the rats in groups SC and SL were killed in order to observe the resorption lacunas and to evaluate whether LLLT had any positive effect on root resorption...
November 2015: Lasers in Medical Science
Linjin Li, Yue Pan, Zhiliang Weng, Wenshuo Bao, Zhixian Yu, Feng Wang
PURPOSE: The aim of this study was to compare the efficacy and safety between pneumatic and holmium:yttrium-aluminum-garnet (Ho:YAG) laser in the treatment of patients with ureteral stones located in the middle and distal ureter. PATIENTS AND METHODS: We conducted a prospective study in recruiting 982 eligible patients from 2009 to 2012. Patients were randomly divided into two groups-the pneumatic lithotripsy (PL) group or the Ho:YAG laser lithotripsy (LL) group...
August 2015: Journal of Endourology
Aslan Demir, Mert Ali Karadağ, Kurşat Ceçen, Mehmet Uslu, Omer Erkam Arslan
PURPOSE: To audit the cost of laser versus pneumatic semirigid ureteroscopic lithotripsy and to analyze their relative initial outcomes and cost. METHODS: Hundred and eighty-seven patients who underwent semirigid ureteroscopic lithotripsy were analyzed retrospectively in terms of age and sex of the patients; location and size of the stones; the type of probe and ancillary equipment such as guide wire, basket catheter, JJ stent requirements; irrigation amount; operation time; the cost of the anesthesia and further treatments such as a JJ stent removal operation and shock wave lithotripsy requirements and their costs...
November 2014: International Urology and Nephrology
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