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https://www.readbyqxmd.com/read/28801582/percutaneous-placement-of-iliosacral-screws-under-the-guidance-of-axial-view-projection-of-the-s1-pedicle-a-case-series
#1
Yingchao Yin, Zhiyong Hou, Ruipeng Zhang, Lin Jin, Wei Chen, Yingze Zhang
The aim of this study was to evaluate the safety and efficacy of percutaneous placement of iliosacral screws under the guidance of axial view projection of the S1 pedicle clinically. This case series includes 58 consecutive unstable pelvic injury patients, which were treated with iliosacral screws between July 2011 and July 2016. Patients were divided into two groups: normal sacrum (n = 31) and dysmorphic sacrum (n = 27). A single orthopedic surgeon operated on all patients, with percutaneous placement of iliosacral screws under the guidance of axial view projection of the S1 pedicle...
August 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28748382/hydrogen-rich-saline-prevents-bone-loss-in-diabetic-rats-induced-by-streptozotocin
#2
Jialiang Guo, Weichong Dong, Lin Jin, Pengcheng Wang, Zhiyong Hou, Yingze Zhang
PURPOSE: As an antioxidant molecule, hydrogen has been received much more attention and reported to be used as the treatment strategy for various diseases. In this study, we hypothesize that systemic delivery of hydrogen saline water may improve the reservation of bone tissue in the tibias and femurs of osteoporotic rats caused by diabetes mellitus (DM), which is characterized by increased levels of oxidative stress and overproducing reactive oxygen species (ROS). METHODS: The animals were divided into three groups of 12 animals and lavaged with normal saline (normal control and DM), or hydrogen saline water (DM + HRS)...
July 26, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28666814/national-incidence-of-traumatic-fractures-in-china-a-retrospective-survey-of-512%C3%A2-187-individuals
#3
Wei Chen, Hongzhi Lv, Song Liu, Bo Liu, Yanbin Zhu, Xiao Chen, Guang Yang, Lei Liu, Tao Zhang, Haili Wang, Bing Yin, Jialiang Guo, Xiaolin Zhang, Yichong Li, Derek Smith, Pan Hu, Jiayuan Sun, Yingze Zhang
BACKGROUND: Traumatic fractures place a substantial burden on health-care systems worldwide. Although detailed information about incidence, distribution, and risk factors for traumatic fractures is vital for planning and prevention, in China, national data are unavailable. We aimed to do an up-to-date national survey on the population-weighted incidence of traumatic fractures in China. METHODS: The China National Fracture Study (CNFS) was a retrospective epidemiological study that recruited a nationally representative sample from eight provinces, 24 urban cities, and 24 rural counties in China using stratified random sampling and the probability proportional to size method...
June 27, 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28660328/radiological-study-of-the-secondary-reduction-effect-of-early-functional-exercise-on-displaced-intra-articular-calcaneal-fractures-after-internal-compression-fixation
#4
Wei Chen, Bo Liu, Hongzhi Lv, Yanling Su, Xiao Chen, Yanbin Zhu, Chenguang Du, Xiaolin Zhang, Yingze Zhang
PURPOSE: Early post-operative exercise and weight-bearing activities are found to improve the functional recovery of patients with displaced intra-articular calcaneal fractures (DIACFs). We hypothesized that early functional exercise after surgery might have a secondary reduction effect on the subtalar joint, in particular the smaller fracture fragments that were not fixed firmly. A prospective study was conducted to verify this hypothesis. METHODS: From December 2012 to September 2013, patients with unilateral DIACFs were enrolled and received a treatment consisting of percutaneous leverage and minimally invasive fixation...
June 28, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28655630/a-novel-anterior-approach-for-the-fixation-of-ulnar-coronoid-process-fractures
#5
Xiaohua Yang, Wenli Chang, Wei Chen, Song Liu, Yanbin Zhu, Yingze Zhang
BACKGROUND: There is no universally accepted approachto the elbow for the fixation of coronoid process fractures.This study aims to introduce a novel anterior surgicalapproach for the fixation of the ulnar coronoid fracture, with minimal surgical dissection damage and excellent visualization for reduction and internal fixation. HYPOTHESIS: The anterior approach can facilitatesatisfactory outcomesfor coronoid process fractures. MATERIAL AND METHODS: From February 2010 to July 2014, 12 patients (8 males and 4 females; range 14-62 years; mean age 31 years) with a closed fracture of the coronoid process of the ulna were included in this study...
June 24, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28648750/muc5b-and-short-telomere-length-in-hypersensitivity-pneumonitis
#6
Yingze Zhang
No abstract text is available yet for this article.
August 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28578086/is-intramedullary-fixation-of-displaced-midshaft-clavicle-fracture-superior-to-plate-fixation-evidence-from-a-systematic-review-of-discordant-meta-analyses
#7
REVIEW
Bin Xu, Yongsheng Lin, Zhihong Wang, Junming Cao, Yipeng Yang, Hehuan Xia, Yingze Zhang
OBJECTIVE: An increasing number of meta-analyses comparing intramedullary fixation (IF) with plate fixation (PF) for displaced midshaft clavicle fracture have been reported, but the inconsistent results obtained might confuse decision-making. We systematically reviewed discordant meta-analyses for assisting the decision-maker in interpreting and selecting amongst discordant meta-analyses and providing surgical recommendations for displaced midshaft clavicle fracture according to currently best available evidence...
July 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28522831/scaling-of-average-receiving-time-on-weighted-polymer-networks-with-some-topological-properties
#8
Dandan Ye, Song Liu, Jia Li, Fei Zhang, Changling Han, Wei Chen, Yingze Zhang
In this paper, a family of the weighted polymer networks is introduced depending on the number of copies f and a weight factor r. The topological properties of weighted polymer networks can be completely analytically characterized in terms of the involved parameters and/or of the fractal dimension. Moreover, assuming that the walker, at each step, starting from its current node, moves to any of its neighbors with probability proportional to the weight of edge linking them, namely weight-dependent walk. Then, we calculate the average receiving time (ART) with weighted-dependent walks, which is the sum of mean first-passage times (MFPTs) for all nodes absorpt at the trap located at the central node as a recursive relation...
May 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28506314/application-of-intraoperative-limb-length-measurement-by-a-new-osteotomy-device-in-hemiarthroplasty-for-treating-femoral-neck-fracture
#9
Zhanle Zheng, Lei Yang, Yanling Su, Xian Yu, Zhiyong Hou, Yingze Zhang
BACKGROUND: Limb length discrepancy is one of the most common complications after hip arthroplasty. We developed a device - intraoperative limb-length measurement and osteotomy device (ILMOD), and applied it to patients who were treated with hemiarthroplasty for femoral neck fracture to improve limb length discrepancy by providing an accurate osteotomy during hemi-arthroplasty. METHODS: Between April 2012 and October 2013, 65 patients were treated with hip hemiarthroplasty for femoral neck fracture at our trauma center...
May 15, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28441029/variable-susceptibility-to-cigarette-smoke-induced-emphysema-in-34-inbred-strains-of-mice-implicates-abi3bp-in-emphysema-susceptibility
#10
Josiah E Radder, Alyssa D Gregory, Adriana S Leme, Michael H Cho, Yanxia Chu, Neil J Kelly, Per Bakke, Amund Gulsvik, Augusto A Litonjua, David Sparrow, Terri H Beaty, James D Crapo, Edwin K Silverman, Yingze Zhang, Annerose Berndt, Steven D Shapiro
RATIONALE: Chronic obstructive pulmonary disease (COPD) is caused by a complex interaction of environmental exposures, most commonly cigarette smoke, and genetic factors. Chronic cigarette smoke exposure in the mouse is a commonly used animal model of COPD. We aimed to expand our knowledge of the variable susceptibility of inbred strains to this model and test for genetic variants associated with this trait. OBJECTIVE: To measure differential susceptibility to cigarette smoke-induced emphysema in the mouse, identify genetic loci associated with this quantitative trait, and find homologous human genes associated with COPD...
April 25, 2017: American Journal of Respiratory Cell and Molecular Biology
https://www.readbyqxmd.com/read/28431530/are-there-too-many-screw-holes-in-plates-for-fracture-fixation
#11
Hongzhi Lv, Wenli Chang, Peizhi Yuwen, Na Yang, Xiaoli Yan, Yingze Zhang
BACKGROUND: Implant breakage after the fixation of traumatic fractures is rare; however, when it occurs, it is debilitating for the patients and a challenge for surgeons. The purpose of this study was to analyze and identify the independent risk factors for implant breakage of traumatic fractures treated with plate osteosynthesis. METHODS: We reviewed the medical records of patients with a fracture to any part of their four extremities, clavicle, hand or foot, who underwent surgical plate osteosynthesis from January 2005 to January 2015, and who sustained a subsequent implant breakage...
April 21, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28389838/intramedullary-nail-versus-volar-locking-plate-fixation-for-the-treatment-of-extra-articular-or-simple-intra-articular-distal-radius-fractures-systematic-review-and-meta-analysis
#12
REVIEW
Bing Zhang, Hengrui Chang, Kunlun Yu, Jiangbo Bai, Dehu Tian, Guisheng Zhang, Xinzhong Shao, Yingze Zhang
AIMS: This study aims to compare the outcomes of intramedullary nail (IMN) and volar locking plate (VLP) fixation for treatment of extra-articular or simple intra-articular distal radius fractures. METHODS: PubMed, Embase, Medline and Cochrane Collaboration Central databases were searched for studies that compared the results of IMN and VLP fixation for the treatment of distal radius fractures up to March 2016. Stata 11.0 was used to perform the meta-analysis. RESULTS: Six randomized controlled trials (RCT) and two retrospective studies were included in this review, including 463 patients...
April 7, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28385655/incidence-and-risk-factors-for-surgical-site-infection-after-open-reduction-and-internal-fixation-of-tibial-plateau-fracture-a-systematic-review-and-meta-analysis
#13
REVIEW
Jiashen Shao, Hengrui Chang, Yanbin Zhu, Wei Chen, Zhanle Zheng, Huixin Zhang, Yingze Zhang
BACKGROUND: This study aimed to quantitatively summarize the risk factors associated with surgical site infection after open reduction and internal fixation of tibial plateau fracture. METHODS: Medline, Embase, CNKI, Wanfang database and Cochrane central database were searched for relevant original studies from database inception to October 2016. Eligible studies had to meet quality assessment criteria according to the Newcastle-Ottawa Scale, and had to evaluate the risk factors for surgical site infection after open reduction and internal fixation of tibial plateau fracture...
April 4, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28361467/effectiveness-of-decompression-alone-versus-decompression-plus-fusion-for-lumbar-spinal-stenosis-a-systematic-review-and-meta-analysis
#14
Wenli Chang, Peizhi Yuwen, Yanbing Zhu, Ning Wei, Chen Feng, Yingze Zhang, Wei Chen
INTRODUCTION: The debate on efficacy of fusion added to decompression for lumbar spinal stenosis (LSS) is ongoing. No meta-analysis has compared the effectiveness of decompression versus decompression plus fusion in treating patients with LSS. METHODS: A literature search was performed in the Web of Science, PubMed, Embase, and Springer databases from 1970 to 2016. Relevant references were selected and the included studies were manually reviewed. We included trials evaluating decompression surgery compared to decompression plus fusion surgery in treating patients with LSS...
May 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28338494/combined-knockdown-of-d-dopachrome-tautomerase-and-migration-inhibitory-factor-inhibits-the-proliferation-migration-and-invasion-in-human-cervical-cancer
#15
Qingying Wang, Yingze Wei, Jiawen Zhang
OBJECTIVE: D-dopachrome tautomerase (D-DT) is a homologue of macrophage migration inhibitory factor (MIF) with similar functions. However, the possible biological roles of D-DT in cervical cancer remain unknown so far. METHODS: D-dopachrome tautomerase was assessed by immunohistochemistry in 83 cervical cancer and 31 normal cervix tissues. The stable knockdown of D-DT and MIF by lentivirus-delivered short hairpin RNA was established, and tumor growth was examined in vitro and in vivo...
May 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28303656/incidence-and-risks-for-surgical-site-infection-after-adult-tibial-plateau-fractures-treated-by-orif-a-prospective-multicentre-study
#16
Yanbin Zhu, Song Liu, Xiaolin Zhang, Wei Chen, Yingze Zhang
Tibial plateau fractures are difficult to treat and more likely complicated by subsequent surgical site infection (SSI). There is limited information about its characteristics and related risk factors for SSI. This study was designed as a prospective and multicentre one to address this issue. From July to 15 November in 2014, 235 patients with tibial plateau fractures were treated by open reduction and internal fixation (ORIF) and followed up with complete data. Twelve patients (5·1%, 12/235) developed SSI, with 2·1% for deep SSI and 3·0% for superficial SSI...
March 16, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28288923/effects-of-alendronate-on-lumbar-intervertebral-disc-degeneration-with-bone-loss-in-ovariectomized-rats
#17
Huiping Song, Yang Luo, Wenya Wang, Shuyang Li, Kai Yang, Muwei Dai, Yong Shen, Yingze Zhang, Liu Zhang
BACKGROUND CONTEXT: Osteoporosis adversely affects disc degeneration cascades, and prophylactic alendronate (ALN) helps delay intervertebral disc degeneration (IDD) in ovariectomized (OVX) rats. However, there remains no information regarding whether ALN affects IDD with bone loss. PURPOSE: This study aimed to observe the effects of ALN on degenerative discs with bone loss induced by OVX in rats. STUDY DESIGN: This study used controlled in vivo experiments in rodents...
March 10, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28242066/insertion-of-psoas-minor-tendon-at-pelvic-brim-a-novel-anatomic-landmark-for-extra-articular-screw-placement-through-stoppa-approach
#18
Ruipeng Zhang, Zhiyong Hou, Liping Zhang, Yingchao Yin, Wei Chen, Yingze Zhang
BACKGROUND: The psoas minor partially inserted to the superior pelvic brim. And the plate used to fix the acetabular fracture has always been positioned at the pelvic brim after reduction through the Stoppa approach. However, there are few studies depicting the clinical significance of the psoas minor. The purpose of this paper was to explore the relationship between the insertion of the psoas minor tendon at the pelvic brim (IPMTPB) and screw placement through the Stoppa approach. MATERIALS AND METHODS: Fifteen cadavers were dissected for adequate exposure to IPMTPB in our study...
April 2017: Injury
https://www.readbyqxmd.com/read/28199135/extreme-trait-whole-genome-sequencing-identifies-ptpro-as-a-novel-candidate-gene-in-emphysema-with-severe-airflow-obstruction
#19
Josiah E Radder, Yingze Zhang, Alyssa D Gregory, Shibing Yu, Neil J Kelly, Joseph K Leader, Naftali Kaminski, Frank C Sciurba, Steven D Shapiro
RATIONALE: Genetic association studies in chronic obstructive pulmonary disease have primarily tested for association with common variants, the results of which explain only a portion of disease heritability. Because rare variation is also likely to contribute to susceptibility, we used whole-genome sequencing of subjects with clinically extreme phenotypes to identify genomic regions enriched for rare variation contributing to chronic obstructive pulmonary disease susceptibility. OBJECTIVES: To identify regions of rare genetic variation contributing to emphysema with severe airflow obstruction...
July 15, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28179498/loss-of-twist1-in-the-mesenchymal-compartment-promotes-increased-fibrosis-in-experimental-lung-injury-by-enhanced-expression-of-cxcl12
#20
Jiangning Tan, John R Tedrow, Mehdi Nouraie, Justin A Dutta, David T Miller, Xiaoyun Li, Shibing Yu, Yanxia Chu, Brenda Juan-Guardela, Naftali Kaminski, Kritika Ramani, Partha S Biswas, Yingze Zhang, Daniel J Kass
Idiopathic pulmonary fibrosis (IPF) is a disease characterized by the accumulation of apoptosis-resistant fibroblasts in the lung. We have previously shown that high expression of the transcription factor Twist1 may explain this prosurvival phenotype in vitro. However, this observation has never been tested in vivo. We found that loss of Twist1 in COL1A2(+) cells led to increased fibrosis characterized by very significant accumulation of T cells and bone marrow-derived matrix-producing cells. We found that Twist1-null cells expressed high levels of the T cell chemoattractant CXCL12...
March 15, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
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