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https://www.readbyqxmd.com/read/28431530/are-there-too-many-screw-holes-in-plates-for-fracture-fixation
#1
Hongzhi Lv, Wenli Chang, Peizhi Yuwen, Na Yang, Xiaoli Yan, Yingze Zhang
BACKGROUND: Implant breakage after the fixation of traumatic fractures is rare; however, when it occurs, it is debilitating for the patients and a challenge for surgeons. The purpose of this study was to analyze and identify the independent risk factors for implant breakage of traumatic fractures treated with plate osteosynthesis. METHODS: We reviewed the medical records of patients with a fracture to any part of their four extremities, clavicle, hand or foot, who underwent surgical plate osteosynthesis from January 2005 to January 2015, and who sustained a subsequent implant breakage...
April 21, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28389838/intramedullary-nail-versus-volar-locking-plate-fixation-for-the-treatment-of-extra-articular-or-simple-intra-articular-distal-radius-fractures-systematic-review-and-meta-analysis
#2
REVIEW
Bing Zhang, Hengrui Chang, Kunlun Yu, Jiangbo Bai, Dehu Tian, Guisheng Zhang, Xinzhong Shao, Yingze Zhang
AIMS: This study aims to compare the outcomes of intramedullary nail (IMN) and volar locking plate (VLP) fixation for treatment of extra-articular or simple intra-articular distal radius fractures. METHODS: PubMed, Embase, Medline and Cochrane Collaboration Central databases were searched for studies that compared the results of IMN and VLP fixation for the treatment of distal radius fractures up to March 2016. Stata 11.0 was used to perform the meta-analysis. RESULTS: Six randomized controlled trials (RCT) and two retrospective studies were included in this review, including 463 patients...
April 7, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28385655/incidence-and-risk-factors-for-surgical-site-infection-after-open-reduction-and-internal-fixation-of-tibial-plateau-fracture-a-systematic-review-and-meta-analysis
#3
REVIEW
Jiashen Shao, Hengrui Chang, Yanbin Zhu, Wei Chen, Zhanle Zheng, Huixin Zhang, Yingze Zhang
BACKGROUND: This study aimed to quantitatively summarize the risk factors associated with surgical site infection after open reduction and internal fixation of tibial plateau fracture. METHODS: Medline, Embase, CNKI, Wanfang database and Cochrane central database were searched for relevant original studies from database inception to October 2016. Eligible studies had to meet quality assessment criteria according to the Newcastle-Ottawa Scale, and had to evaluate the risk factors for surgical site infection after open reduction and internal fixation of tibial plateau fracture...
April 4, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28361467/effectiveness-of-decompression-alone-versus-decompression-plus-fusion-for-lumbar-spinal-stenosis-a-systematic-review-and-meta-analysis
#4
Wenli Chang, Peizhi Yuwen, Yanbing Zhu, Ning Wei, Chen Feng, Yingze Zhang, Wei Chen
INTRODUCTION: The debate on efficacy of fusion added to decompression for lumbar spinal stenosis (LSS) is ongoing. No meta-analysis has compared the effectiveness of decompression versus decompression plus fusion in treating patients with LSS. METHODS: A literature search was performed in the Web of Science, PubMed, Embase, and Springer databases from 1970 to 2016. Relevant references were selected and the included studies were manually reviewed. We included trials evaluating decompression surgery compared to decompression plus fusion surgery in treating patients with LSS...
May 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28338494/combined-knockdown-of-d-dopachrome-tautomerase-and-migration-inhibitory-factor-inhibits-the-proliferation-migration-and-invasion-in-human-cervical-cancer
#5
Qingying Wang, Yingze Wei, Jiawen Zhang
OBJECTIVE: D-dopachrome tautomerase (D-DT) is a homologue of macrophage migration inhibitory factor (MIF) with similar functions. However, the possible biological roles of D-DT in cervical cancer remain unknown so far. METHODS: D-dopachrome tautomerase was assessed by immunohistochemistry in 83 cervical cancer and 31 normal cervix tissues. The stable knockdown of D-DT and MIF by lentivirus-delivered short hairpin RNA was established, and tumor growth was examined in vitro and in vivo...
March 23, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28303656/incidence-and-risks-for-surgical-site-infection-after-adult-tibial-plateau-fractures-treated-by-orif-a-prospective-multicentre-study
#6
Yanbin Zhu, Song Liu, Xiaolin Zhang, Wei Chen, Yingze Zhang
Tibial plateau fractures are difficult to treat and more likely complicated by subsequent surgical site infection (SSI). There is limited information about its characteristics and related risk factors for SSI. This study was designed as a prospective and multicentre one to address this issue. From July to 15 November in 2014, 235 patients with tibial plateau fractures were treated by open reduction and internal fixation (ORIF) and followed up with complete data. Twelve patients (5·1%, 12/235) developed SSI, with 2·1% for deep SSI and 3·0% for superficial SSI...
March 16, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28288923/effects-of-alendronate-on-lumbar-intervertebral-disc-degeneration-with-bone-loss-in-ovariectomized-rats
#7
Huiping Song, Yang Luo, Wenya Wang, Shuyang Li, Kai Yang, Muwei Dai, Yong Shen, Yingze Zhang, Liu Zhang
BACKGROUND CONTEXT: Osteoporosis adversely affects disc degeneration cascades, and prophylactic alendronate (ALN) helps delay intervertebral disc degeneration (IDD) in ovariectomized (OVX) rats. However, there remains no information regarding whether ALN affects IDD with bone loss. PURPOSE: This study aimed to observe the effects of ALN on degenerative discs with bone loss induced by OVX in rats. STUDY DESIGN: This study used controlled in vivo experiments in rodents...
March 10, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28242066/insertion-of-psoas-minor-tendon-at-pelvic-brim-a-novel-anatomic-landmark-for-extra-articular-screw-placement-through-stoppa-approach
#8
Ruipeng Zhang, Zhiyong Hou, Liping Zhang, Yingchao Yin, Wei Chen, Yingze Zhang
BACKGROUND: The psoas minor partially inserted to the superior pelvic brim. And the plate used to fix the acetabular fracture has always been positioned at the pelvic brim after reduction through the Stoppa approach. However, there are few studies depicting the clinical significance of the psoas minor. The purpose of this paper was to explore the relationship between the insertion of the psoas minor tendon at the pelvic brim (IPMTPB) and screw placement through the Stoppa approach. MATERIALS AND METHODS: Fifteen cadavers were dissected for adequate exposure to IPMTPB in our study...
February 21, 2017: Injury
https://www.readbyqxmd.com/read/28199135/extreme-trait-whole-genome-sequencing-identifies-ptpro-as-a-novel-candidate-gene-in-emphysema-with-severe-airflow-obstruction
#9
Josiah E Radder, Yingze Zhang, Alyssa D Gregory, Shibing Yu, Neil J Kelly, Joseph K Leader, Naftali Kaminski, Frank C Sciurba, Steven D Shapiro
RATIONALE: Genetic association studies in chronic obstructive pulmonary disease (COPD) have primarily tested for association with common variants, the results of which explain only a portion of disease heritability. As rare variation is also likely to contribute to susceptibility, we employed whole genome sequencing (WGS) of subjects with clinically extreme phenotypes to identify genomic regions enriched for rare variation contributing to COPD susceptibility. OBJECTIVE: Identify regions of rare genetic variation contributing to emphysema with severe airflow obstruction Methods: We identified heavy smokers that were resistant (n=65) or susceptible (n=64) to emphysema with severe airflow obstruction in the Pittsburgh SCCOR cohort...
February 15, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28179498/loss-of-twist1-in-the-mesenchymal-compartment-promotes-increased-fibrosis-in-experimental-lung-injury-by-enhanced-expression-of-cxcl12
#10
Jiangning Tan, John R Tedrow, Mehdi Nouraie, Justin A Dutta, David T Miller, Xiaoyun Li, Shibing Yu, Yanxia Chu, Brenda Juan-Guardela, Naftali Kaminski, Kritika Ramani, Partha S Biswas, Yingze Zhang, Daniel J Kass
Idiopathic pulmonary fibrosis (IPF) is a disease characterized by the accumulation of apoptosis-resistant fibroblasts in the lung. We have previously shown that high expression of the transcription factor Twist1 may explain this prosurvival phenotype in vitro. However, this observation has never been tested in vivo. We found that loss of Twist1 in COL1A2(+) cells led to increased fibrosis characterized by very significant accumulation of T cells and bone marrow-derived matrix-producing cells. We found that Twist1-null cells expressed high levels of the T cell chemoattractant CXCL12...
March 15, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28122417/meta-analysis-of-two-surgical-approaches-for-calcaneal-fractures-sinus-tarsi-versus-extensile-lateral-approach
#11
REVIEW
Fei Zhang, Hongtao Tian, Shilun Li, Bo Liu, Tianhua Dong, Yanbin Zhu, Yingze Zhang
BACKGROUND: There remains a controversy between extensile lateral approach and sinus tarsi approach (STA) to treat calcaneal fractures. The aim of this study is to evaluate the medium- and long-term outcomes of the STA versus extensile lateral approach in terms of intraoperative variables, quality of alignment on a lateral radiograph incidence of wound healing complication, visual analogue scale and American Orthopaedic Foot and Ankle Society for the treatment of calcaneal fractures. METHODS: Relevant original studies were searched in PubMed, Medline and Embase and Chinese National Knowledge Infrastructure (January 1990 and November 2015)...
March 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28096531/the-first-imported-case-of-rift-valley-fever-in-china-reveals-a-genetic-reassortment-of-different-viral-lineages
#12
Jingyuan Liu, Yulan Sun, Weifeng Shi, Shuguang Tan, Yang Pan, Shujuan Cui, Qingchao Zhang, Xiangfeng Dou, Yanning Lv, Xinyu Li, Xitai Li, Lijuan Chen, Chuansong Quan, Qianli Wang, Yingze Zhao, Qiang Lv, Wenhao Hua, Hui Zeng, Zhihai Chen, Haofeng Xiong, Chengyu Jiang, Xinghuo Pang, Fujie Zhang, Mifang Liang, Guizhen Wu, George F Gao, William J Liu, Ang Li, Quanyi Wang
We report the first imported case of Rift Valley fever (RVF) in China. The patient returned from Angola, a non-epidemic country, with an infection of a new reassortant from different lineages of Rift Valley fever viruses (RVFVs). The patient developed multiorgan dysfunction and gradually recovered with continuous renal replacement therapy and a short regimen of methylprednisolone treatment. The disordered cytokines and chemokines in the plasma of the patient revealed hypercytokinemia, but the levels of protective cytokines were low upon admission and fluctuated as the disease improved...
January 18, 2017: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/28093079/albumin-and-surgical-site-infection-risk-in-orthopaedics-a-meta-analysis
#13
Peizhi Yuwen, Wei Chen, Hongzhi Lv, Chen Feng, Yansen Li, Tao Zhang, Pan Hu, Jialiang Guo, Ye Tian, Lei Liu, Jiayuan Sun, Yingze Zhang
BACKGROUD: Surigical site infection has been a challenge for surgeons for many years, the prevalence of serum albumin <3.5g/dL has been reported to be associated with increased orthopaedic complications. However, the prognostic implications and significance of serum albumin <3.5g/dL after orthopaedic surgeries remain ambiguity. In this study, we performed a meta-analysis to access the predictive value of serum albumin level on SSI. METHODS: A basic data search was performed in PubMed and Web of Science, in addition, references were manually searched...
January 16, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28089509/occult-external-iliac-vein-injury-after-anterior-dislocation-of-the-sacroiliac-joint-in-adult-patient
#14
Yueju Liu, Juan Wang, Yingze Zhang
Anterior dislocation of the sacroiliac joint, characterized by dislocation of the ilium anterior to the sacrum, is a subtype of complete posterior pelvic ring disruption. This injury occurs mostly in children. We present an adult patient with anterior dislocation of the sacroiliac joint. It was associated with numerous complications. To the best of our knowledge, it is only the second case reported in the literature.
January 12, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/28074258/the-treatment-options-for-posterior-malleolar-fractures-in-tibial-spiral-fractures
#15
Jialiang Guo, Lei Liu, Zongyou Yang, Zhiyong Hou, Wei Chen, Yingze Zhang
PURPOSE: The posterior malleolar fracture (PMF) in tibial spiral fractures are a common type of complication that occurs in tibial fractures. However, the indication of fixation for posterior fractures is still under debate and varies between different surgeons'. It is not unusual to find the smaller PMF (<25%), which could be treated conservatively within guidelines, treated with internal fixation in clinic. The aim of this study is to evaluate the clinical outcomes of tibial spiral fractures with PMF and provide proper guidance for the treatment of this special fracture...
January 10, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/27975055/clinical-effects-of-the-probing-method-with-depth-gauge-for-determining-the-screw-depth-of-locking-proximal-humeral-plate
#16
RANDOMIZED CONTROLLED TRIAL
Lin Jin, Jialiang Guo, Junfei Guo, Yingchao Yin, Zhiyong Hou, Yingze Zhang
Background. The use of locking plates has gained popularity to treat proximal humeral fractures. However, the complication rates remain high. Biomechanical study suggested that subchondral screw-tip abutment significantly increased the stability of plant. We present a simple method to obtain the proper screw length through the depth gauge in elderly patients and compared the clinical effects with traditional measuring method. Methods. 40 patients were separated into two groups according to the two surgical methods: the probing method with depth gauge and the traditional measuring method...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27939207/source-apportionment-and-heavy-metal-health-risk-hmhr-quantification-from-sources-in-a-southern-city-in-china-using-an-me2-hmhr-model
#17
Xing Peng, GuoLiang Shi, GuiRong Liu, Jiao Xu, YingZe Tian, YuFen Zhang, YinChang Feng, Armistead G Russell
Heavy metals (Cr, Co, Ni, As, Cd, and Pb) can be bound to PM adversely affecting human health. Quantifying the source impacts on heavy metals can provide source-specific estimates of the heavy metal health risk (HMHR) to guide effective development of strategies to reduce such risks from exposure to heavy metals in PM2.5 (particulate matter (PM) with aerodynamic diameter less than or equal to 2.5 μm). In this study, a method combining Multilinear Engine 2 (ME2) and a risk assessment model is developed to more effectively quantify source contributions to HMHR, including heavy metal non-cancer risk (non-HMCR) and cancer risk (HMCR)...
February 2017: Environmental Pollution
https://www.readbyqxmd.com/read/27827384/recurrence-rates-and-risk-factors-for-primary-giant-cell-tumors-around-the-knee-a-multicentre-retrospective-study-in-china
#18
Pan Hu, Liming Zhao, Huilin Zhang, Xiuchun Yu, Zhen Wang, Zhaoming Ye, Sujia Wu, Shibing Guo, Guochuan Zhang, Jinghua Wang, Xianjia Ning, Yongcheng Hu, Yingze Zhang
Giant cell tumors of the bone (GCTBs) are commonly diagnosed in Asian populations, usually around the knee. Herein, we aimed to determine the clinical characteristics, local recurrence rates, and relevant risk factors of primary GCTB around the knee. Univariate and multivariate survival analyses were used to identify the risk factors for local recurrence. Four hundred ten patients with primary GCTB around the knee, treated between March 2000 and June 2014, were recruited from 7 institutions in China. The overall local recurrence rate was 23...
November 9, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27805901/ring-finger-e3-ligase-ppp1r11-regulates-tlr2-signaling-and-innate-immunity
#19
Alison C McKelvey, Travis B Lear, Sarah R Dunn, John Evankovich, James D Londino, Joseph S Bednash, Yingze Zhang, Bryan J McVerry, Yuan Liu, Bill B Chen
Toll-like receptor 2 (TLR2) is a pattern recognition receptor that recognizes many types of PAMPs that originate from gram-positive bacteria. Here we describe a novel mechanism regulating TLR2 protein expression and subsequent cytokine release through the ubiquitination and degradation of the receptor in response to ligand stimulation. We show a new mechanism in which an uncharacterized RING finger E3 ligase, PPP1R11, directly ubiquitinates TLR2 both in vitro and in vivo, which leads to TLR2 degradation and disruption of the signaling cascade...
November 2, 2016: ELife
https://www.readbyqxmd.com/read/27782258/in-situ-dual-functional-water-purification-with-simultaneous-oil-removal-and-visible-light-catalysis
#20
Na Liu, Ruixiang Qu, Yuning Chen, Yingze Cao, Weifeng Zhang, Xin Lin, Yen Wei, Lin Feng, Lei Jiang
Dual purification of both oily wastewater and dye-polluted water for enhancing the use of freshwater is an urgent task. We report herein, the facile synthesis of inorganic semiconductor nanomaterials anchored mesh for in situ dual-functional water purification. This resultant mesh combines the excellent capacity of oil removal and the advantage of photocatalytic performance for dye degradation under visible light irradiation at the same time. In addition, the mesh was easily regenerated and remained unaltered in photocatalytic performance over five successive dye degradation cycles...
October 26, 2016: Nanoscale
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