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https://www.readbyqxmd.com/read/29155842/posterior-column-acetabular-fracture-fixation-using-a-w-shaped-angular-plate-a-biomechanical-analysis
#1
Ke Su, Song Liu, Tao Wu, Yingchao Yin, Ruipeng Zhang, Shilun Li, Yingze Zhang
OBJECTIVE: The purpose of this study was to compare the stability and feasibility of four fixation constructs in a posterior column acetabular fracture: one reconstruction plate, one reconstruction plate and lag screw, two reconstruction plates, and a W-shaped acetabular angular plate. METHODS: Twenty embalmed cadaveric pelvises with a posterior column acetabular fractures were allocated to one of four groups: 1) a reconstruction plate, 2) a reconstruction plate with a posterior column lag screw, 3) double reconstruction plates, and 4) a W-shaped acetabular angular plate...
2017: PloS One
https://www.readbyqxmd.com/read/29116324/displaced-intra-articular-calcaneal-fractures-classification-and-treatment
#2
Ning Wei, Yabin Zhou, Wenli Chang, Yingze Zhang, Wei Chen
The calcaneus is the most commonly fractured tarsal bone. Displaced intraarticular calcaneal fractures are usually caused by a fall from height with one or both heels directly hitting the ground. Displaced intra-articular calcaneal fractures are complex and highly disabling injuries. There is ongoing debate regarding the optimal treatment for each type of displaced intra-articular calcaneal fracture. This review aims to summarize the classification of, various treatment options for, prevention of perioperative complications in, and management algorithms for displaced intra-articular calcaneal fractures...
November 1, 2017: Orthopedics
https://www.readbyqxmd.com/read/29108027/local-application-of-an-ibandronate-collagen-sponge-improves-femoral-fracture-healing-in-ovariectomized-rats
#3
Jialiang Guo, Qi Zhang, Jia Li, Yansong Liu, Zhiyong Hou, Wei Chen, Lin Jin, Ye Tian, Linlin Ju, Bo Liu, Tianhua Dong, Fei Zhang, Yingze Zhang
Non-union is a major clinical problem in the healing of fractures, especially in patients with osteoporosis. The systemic administration of drugs is time consuming and large doses are demanding and act slowly, whereas local release acts rapidly, increases the quality and quantity of the bone tissue. We hypothesize that local delivery demonstrates better therapeutic effects on an osteoporotic fracture. The aim of this paper is to investigate the effect of the local application of ibandronate loaded with a collagen sponge on regulating bone formation and remodeling in an osteoporotic rat model of fracture healing...
2017: PloS One
https://www.readbyqxmd.com/read/29101314/clinical-and-radiological-analysis-of-bryan-cervical-artificial-disc-replacement-for-skip-multi-segment-cervical-spondylosis-long-term-follow-up-results
#4
Zikun Shang, Yingze Zhang, Di Zhang, Wenyuan Ding, Yong Shen
BACKGROUND The aim of this study was to retrospectively analyze the clinical and radiological efficacy of Bryan cervical artificial disc replacement (ADR) for "skip" multi-segment cervical spondylosis (SCS). MATERIAL AND METHODS We enrolled 49 patients with SCS treated with either Bryan cervical ADR (18 cases) or ACDF (31 cases). Each case was evaluated preoperatively and at more than 48 months postoperatively in follow-up using the JOA, NDI, and VAS. Cervical sagittal curvature, total cervical ROM, and degree of middle segments of motion were also evaluated...
November 4, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28942086/validation-of-a-52-gene-risk-profile-for-outcome-prediction-in-patients-with-idiopathic-pulmonary-fibrosis-an-international-multicentre-cohort-study
#5
Jose D Herazo-Maya, Jiehuan Sun, Philip L Molyneaux, Qin Li, Julian A Villalba, Argyrios Tzouvelekis, Heather Lynn, Brenda M Juan-Guardela, Cristobal Risquez, Juan C Osorio, Xiting Yan, George Michel, Nachelle Aurelien, Kathleen O Lindell, Melinda J Klesen, Miriam F Moffatt, William O Cookson, Yingze Zhang, Joe G N Garcia, Imre Noth, Antje Prasse, Ziv Bar-Joseph, Kevin F Gibson, Hongyu Zhao, Erica L Herzog, Ivan O Rosas, Toby M Maher, Naftali Kaminski
BACKGROUND: The clinical course of idiopathic pulmonary fibrosis (IPF) is unpredictable. Clinical prediction tools are not accurate enough to predict disease outcomes. METHODS: We enrolled patients with IPF diagnosis in a six-cohort study at Yale University (New Haven, CT, USA), Imperial College London (London, UK), University of Chicago (Chicago, IL, USA), University of Pittsburgh (Pittsburgh, PA, USA), University of Freiburg (Freiburg im Breisgau, Germany), and Brigham and Women's Hospital-Harvard Medical School (Boston, MA, USA)...
November 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28937464/comparison-of-clinical-outcomes-after-anterior-cervical-discectomy-and-fusion-versus-cervical-total-disk-replacement-in-patients-with-modic-2-changes-on-mri
#6
Jia Li, Di Zhang, Wenyuan Ding, Yingze Zhang, Yong Shen
STUDY DESIGN: A retrospective investigation. OBJECTIVE: The aim of this research is to compare the clinical and radiologic outcomes of patients with Modic-2 changes who underwent anterior cervical discectomy and fusion (ACDF) or cervical total disk replacement (TDR) in single level. SUMMARY OF BACKGROUND DATA: There were few studies focused on the clinical and radiologic outcomes of patients with Modic-2 changes who underwent ACDF or cervical TDR in single level...
October 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28917539/hemagglutinin-specific-cd4-t-cell-responses-following-2009-ph1n1-inactivated-split-vaccine-inoculation-in-humans
#7
Shuguang Tan, Shihong Zhang, Bin Wu, Yingze Zhao, Wei Zhang, Min Han, Ying Wu, Guoli Shi, Yingxia Liu, Jinghua Yan, Guizhen Wu, Hua Wang, George F Gao, Fengcai Zhu, William J Liu
Influenza A virus remains a major threat to public health, and the inactivated split-virus vaccine is the most prevalent vaccine used worldwide. However, our knowledge about cellular immune responses to the inactivated influenza virus vaccine and its correlation with humoral responses are yet limited, which has restricted our understanding of the vaccine's protective mechanisms. Herein, in two clinical trials, T-cell responses specific for both previously identified human leucocyte antigen (HLA)-I-restricted epitopes from influenza virus and hemagglutinin (HA) protein were longitudinally investigated before, during, and after a two-dose vaccination with the inactivated 2009 pandemic H1N1 (2009-pH1N1) vaccine...
September 13, 2017: Vaccine
https://www.readbyqxmd.com/read/28910816/mediastinal-and-subcutaneous-chest-fat-are-differentially-associated-with-emphysema-progression-and-clinical-outcomes-in-smokers
#8
Jon Grace, Joseph K Leader, Seyed M Nouraie, Jiantao Pu, Divay Chandra, Yingze Zhang, Frank C Sciurba, Jessica Bon
BACKGROUND: Studies have demonstrated both positive and negative effects of obesity on clinical outcomes in chronic obstructive pulmonary disease (COPD). In other chronic diseases, fat location is differentially associated with disease outcomes; however, this relationship has not been well studied in COPD. OBJECTIVE: To determine if fat location explains the differential association of body mass index (BMI) with clinical outcome measures in smokers. METHODS: Baseline and 6-year chest computed tomography scans from 68 current and former smokers were used to quantify mediastinal and subcutaneous fat...
September 15, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28808345/minimally-invasive-treatment-of-both-column-acetabular-fractures-through-the-stoppa-combined-with-iliac-fossa-approach
#9
Ruipeng Zhang, Yingchao Yin, Shilun Li, Zhiyong Hou, Juan Wang, Wei Chen, Yingze Zhang
Both-column fractures are the most complicated group of acetabular fractures. Although great progress of surgical technique has been made, the choice of approach is controversial. All the fragments could be exposed and managed through combined ilioinguinal and Kocher-Langenbeck (IL+KL) approaches, which has been widely used to conduct the both-column fractures. However, the clinical popularization may be restricted for high rate of complication. Most internal area of the hemipelvis could be exposed through Stoppa combined with iliac fossa (S+IF) approach...
August 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28801582/percutaneous-placement-of-iliosacral-screws-under-the-guidance-of-axial-view-projection-of-the-s1-pedicle-a-case-series
#10
Yingchao Yin, Zhiyong Hou, Ruipeng Zhang, Lin Jin, Wei Chen, Yingze Zhang
The aim of this study was to evaluate the safety and efficacy of percutaneous placement of iliosacral screws under the guidance of axial view projection of the S1 pedicle clinically. This case series includes 58 consecutive unstable pelvic injury patients, which were treated with iliosacral screws between July 2011 and July 2016. Patients were divided into two groups: normal sacrum (n = 31) and dysmorphic sacrum (n = 27). A single orthopedic surgeon operated on all patients, with percutaneous placement of iliosacral screws under the guidance of axial view projection of the S1 pedicle...
August 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28748382/hydrogen-rich-saline-prevents-bone-loss-in-diabetic-rats-induced-by-streptozotocin
#11
Jialiang Guo, Weichong Dong, Lin Jin, Pengcheng Wang, Zhiyong Hou, Yingze Zhang
PURPOSE: As an antioxidant molecule, hydrogen has been received much more attention and reported to be used as the treatment strategy for various diseases. In this study, we hypothesize that systemic delivery of hydrogen saline water may improve the reservation of bone tissue in the tibias and femurs of osteoporotic rats caused by diabetes mellitus (DM), which is characterized by increased levels of oxidative stress and overproducing reactive oxygen species (ROS). METHODS: The animals were divided into three groups of 12 animals and lavaged with normal saline (normal control and DM), or hydrogen saline water (DM + HRS)...
October 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28666814/national-incidence-of-traumatic-fractures-in-china-a-retrospective-survey-of-512%C3%A2-187-individuals
#12
Wei Chen, Hongzhi Lv, Song Liu, Bo Liu, Yanbin Zhu, Xiao Chen, Guang Yang, Lei Liu, Tao Zhang, Haili Wang, Bing Yin, Jialiang Guo, Xiaolin Zhang, Yichong Li, Derek Smith, Pan Hu, Jiayuan Sun, Yingze Zhang
BACKGROUND: Traumatic fractures place a substantial burden on health-care systems worldwide. Although detailed information about incidence, distribution, and risk factors for traumatic fractures is vital for planning and prevention, in China, national data are unavailable. We aimed to do an up-to-date national survey on the population-weighted incidence of traumatic fractures in China. METHODS: The China National Fracture Study (CNFS) was a retrospective epidemiological study that recruited a nationally representative sample from eight provinces, 24 urban cities, and 24 rural counties in China using stratified random sampling and the probability proportional to size method...
June 27, 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28660328/radiological-study-of-the-secondary-reduction-effect-of-early-functional-exercise-on-displaced-intra-articular-calcaneal-fractures-after-internal-compression-fixation
#13
Wei Chen, Bo Liu, Hongzhi Lv, Yanling Su, Xiao Chen, Yanbin Zhu, Chenguang Du, Xiaolin Zhang, Yingze Zhang
PURPOSE: Early post-operative exercise and weight-bearing activities are found to improve the functional recovery of patients with displaced intra-articular calcaneal fractures (DIACFs). We hypothesized that early functional exercise after surgery might have a secondary reduction effect on the subtalar joint, in particular the smaller fracture fragments that were not fixed firmly. A prospective study was conducted to verify this hypothesis. METHODS: From December 2012 to September 2013, patients with unilateral DIACFs were enrolled and received a treatment consisting of percutaneous leverage and minimally invasive fixation...
September 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28655630/a-novel-anterior-approach-for-the-fixation-of-ulnar-coronoid-process-fractures
#14
X Yang, W Chang, W Chen, S Liu, Y Zhu, Y Zhang
BACKGROUND: There is no universally accepted approach to the elbow for the fixation of coronoid process fractures. This study aims to introduce a novel anterior surgical approach for the fixation of the ulnar coronoid fracture, with minimal surgical dissection damage and excellent visualization for reduction and internal fixation. HYPOTHESIS: The anterior approach can facilitate satisfactory outcomes for coronoid process fractures. MATERIAL AND METHODS: From February 2010 to July 2014, 12 patients (8 males and 4 females; range 14-62years; mean age 31years) with a closed fracture of the coronoid process of the ulna were included in this study...
June 24, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28648750/muc5b-and-short-telomere-length-in-hypersensitivity-pneumonitis
#15
Yingze Zhang
No abstract text is available yet for this article.
August 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28578086/is-intramedullary-fixation-of-displaced-midshaft-clavicle-fracture-superior-to-plate-fixation-evidence-from-a-systematic-review-of-discordant-meta-analyses
#16
REVIEW
Bin Xu, Yongsheng Lin, Zhihong Wang, Junming Cao, Yipeng Yang, Hehuan Xia, Yingze Zhang
OBJECTIVE: An increasing number of meta-analyses comparing intramedullary fixation (IF) with plate fixation (PF) for displaced midshaft clavicle fracture have been reported, but the inconsistent results obtained might confuse decision-making. We systematically reviewed discordant meta-analyses for assisting the decision-maker in interpreting and selecting amongst discordant meta-analyses and providing surgical recommendations for displaced midshaft clavicle fracture according to currently best available evidence...
July 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28522831/scaling-of-average-receiving-time-on-weighted-polymer-networks-with-some-topological-properties
#17
Dandan Ye, Song Liu, Jia Li, Fei Zhang, Changling Han, Wei Chen, Yingze Zhang
In this paper, a family of the weighted polymer networks is introduced depending on the number of copies f and a weight factor r. The topological properties of weighted polymer networks can be completely analytically characterized in terms of the involved parameters and/or of the fractal dimension. Moreover, assuming that the walker, at each step, starting from its current node, moves to any of its neighbors with probability proportional to the weight of edge linking them, namely weight-dependent walk. Then, we calculate the average receiving time (ART) with weighted-dependent walks, which is the sum of mean first-passage times (MFPTs) for all nodes absorpt at the trap located at the central node as a recursive relation...
May 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28506314/application-of-intraoperative-limb-length-measurement-by-a-new-osteotomy-device-in-hemiarthroplasty-for-treating-femoral-neck-fracture
#18
Zhanle Zheng, Lei Yang, Yanling Su, Xian Yu, Zhiyong Hou, Yingze Zhang
BACKGROUND: Limb length discrepancy is one of the most common complications after hip arthroplasty. We developed a device - intraoperative limb-length measurement and osteotomy device (ILMOD), and applied it to patients who were treated with hemiarthroplasty for femoral neck fracture to improve limb length discrepancy by providing an accurate osteotomy during hemi-arthroplasty. METHODS: Between April 2012 and October 2013, 65 patients were treated with hip hemiarthroplasty for femoral neck fracture at our trauma center...
May 15, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28441029/variable-susceptibility-to-cigarette-smoke-induced-emphysema-in-34-inbred-strains-of-mice-implicates-abi3bp-in-emphysema-susceptibility
#19
Josiah E Radder, Alyssa D Gregory, Adriana S Leme, Michael H Cho, Yanxia Chu, Neil J Kelly, Per Bakke, Amund Gulsvik, Augusto A Litonjua, David Sparrow, Terri H Beaty, James D Crapo, Edwin K Silverman, Yingze Zhang, Annerose Berndt, Steven D Shapiro
Chronic obstructive pulmonary disease (COPD) is caused by a complex interaction of environmental exposures, most commonly cigarette smoke, and genetic factors. Chronic cigarette smoke exposure in the mouse is a commonly used animal model of COPD. We aimed to expand our knowledge about the variable susceptibility of inbred strains to this model and test for genetic variants associated with this trait. To that end, we sought to measure differential susceptibility to cigarette smoke-induced emphysema in the mouse, identify genetic loci associated with this quantitative trait, and find homologous human genes associated with COPD...
September 2017: American Journal of Respiratory Cell and Molecular Biology
https://www.readbyqxmd.com/read/28431530/are-there-too-many-screw-holes-in-plates-for-fracture-fixation
#20
Hongzhi Lv, Wenli Chang, Peizhi Yuwen, Na Yang, Xiaoli Yan, Yingze Zhang
BACKGROUND: Implant breakage after the fixation of traumatic fractures is rare; however, when it occurs, it is debilitating for the patients and a challenge for surgeons. The purpose of this study was to analyze and identify the independent risk factors for implant breakage of traumatic fractures treated with plate osteosynthesis. METHODS: We reviewed the medical records of patients with a fracture to any part of their four extremities, clavicle, hand or foot, who underwent surgical plate osteosynthesis from January 2005 to January 2015, and who sustained a subsequent implant breakage...
April 21, 2017: BMC Surgery
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