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Electroconvulsive therapy and schizophrenia

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https://www.readbyqxmd.com/read/28769540/electroconvulsive-therapy-for-agitation-in-schizophrenia-metaanalysis-of-randomized-controlled-trials
#1
Xiaojing Gu, Wei Zheng, Tong Guo, Gabor S Ungvari, Helen F K Chiu, Xiaolan Cao, Carl D'Arcy, Xiangfei Meng, Yuping Ning, Yutao Xiang
BACKGROUND: Agitation poses a significant challenge in the treatment of schizophrenia. Electroconvulsive therapy (ECT) is a fast, effective and safe treatment for a variety of psychiatric disorders, but no meta-analysis of ECT treatment for agitation in schizophrenia has yet been reported. AIMS: To systematically evaluate the efficacy and safety of ECT alone or ECT-antipsychotics (APs) combination for agitation in schizophrenia. METHODS: Systematic literature search of randomized controlled trials (RCTs) was performed...
February 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28754582/catatonia-in-children-and-adolescents-new-perspectives
#2
Xavier Benarous, Marie Raffin, Vladimir Ferrafiat, Angèle Consoli, David Cohen
INTRODUCTION: Catatonia is a rare and severe psychomotor condition in children and adolescents. In the current report, we aimed to review the recent literature. METHOD: Using a PRISMA approach, we searched MEDLINE between 1982 and 2017 using the keywords 'CATATONIA' and 'CHILD' or 'ADOLESCENT'. In total, we reviewed 130 reports (controlled study, N=4; clinical chart, N=23; case report, N=54; and editorial/review, N=42). RESULTS: Several aspects seem to be age specific: (1) although the clinical presentation resembles that in adults, some symptoms are important in children and adolescents (e...
July 25, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28694625/does-gender-influence-electroconvulsive-therapy-sessions-required-across-psychiatric-diagnoses-a-5-year-experience-from-a-single-center
#3
Harshini Manohar, Karthick Subramanian, Vikas Menon, Shivanand Kattimani
CONTEXT: There is a paucity of systematic data reflecting the practice of electroconvulsive therapy (ECT) from developing countries. AIM: We aimed to identify the number of ECT sessions required to yield response and gender diffeferences in the number of sessions across various diagnostic categories. SETTING AND DESIGN: A record-based study from a teaching cum tertiary care hospital in South India. SUBJECTS AND METHODS: Case records of patients who received modified ECT from January 2011 to January 2016 were reviewed...
July 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28663621/effect-of-premedication-with-oral-clonidine-on-hemodynamic-response-during-electroconvulsive-therapy
#4
Mangi Lal Deganwa, Rajesh Sharma, Avneesh Khare, Divya Sharma
BACKGROUND: Electroconvulsive therapy (ECT) is the most effective treatment available for the acute treatment of depression in patients who do not respond to medications. It is generally used as a second line treatment for many psychological disorders, mainly major depression and schizophrenia where medication is not effective. ECT is often associated with some complications such as hypertension, tachycardia arrhythmia and even myocardial infarction. Various methods have been used for prevention or control of these cardiovascular side effects...
April 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28640171/changes-in-electroconvulsive-therapy-practice-in-the-last-12-years-in-hungary
#5
Márton Asztalos, Gabor S Ungvari, Gábor Gazdag
BACKGROUND: Electroconvulsive therapy (ECT) was rarely used in Hungary in 2002, and the majority of patients receiving ECT were diagnosed with schizophrenia. This study aimed to explore the use of ECT in Hungary in 2014. METHODS: Two semi-structured questionnaires were sent to all acute adult psychiatric units in Hungary. The first questionnaire contained items concerning ECT use, and the second explored the reasons for not using ECT. RESULTS: Fifty-eight acute psychiatric inpatient units were identified, and 54 replied...
June 15, 2017: Journal of ECT
https://www.readbyqxmd.com/read/28640170/effectiveness-of-electroconvulsive-therapy-and-associated-cognitive-change-in-schizophrenia-a-naturalistic-comparative-study-of-treating-schizophrenia-with-electroconvulsive-therapy
#6
Phern-Chern Tor, Jiangbo Ying, New Fei Ho, Mingyuan Wang, Donel Martin, Chai Pin Ang, Chunzhen Tan, Lee Shen Yap, Vincent John Magat Lu, Brett Simpson, Yee Ming Mok, Colleen Loo
OBJECTIVE: There is limited evidence regarding the relative treatment effectiveness and cognitive effects of different types of electroconvulsive therapy (ECT) in schizophrenia. In this study, we sought to determine the overall effectiveness and compare the symptomatic and cognitive outcomes of patients with schizophrenia who received different modalities of ECT treatment. METHODS: Patients received 1 of 4 of the following ECT modalities: bitemporal ECT with age-based dosing, right unilateral ECT with seizure threshold-based dosing, bitemporal ECT with seizure threshold-based dosing, and bifrontal ECT with seizure threshold-based dosing ECT...
June 15, 2017: Journal of ECT
https://www.readbyqxmd.com/read/28636570/use-of-electroconvulsive-therapy-in-central-eastern-european-countries-an-overview
#7
Gábor Gazdag, Jozef Dragasek, Rozália Takács, Margus Lõokene, Tomasz Sobow, Aleksey Olekseev, Gabor S Ungvari
Though a number of reports on the use of electroconvulsive therapy (ECT) has been published from the Central-Eastern European region over the past two decades, a systematic review of this literature has not been published. Thus the aim of this paper was to review recent trends in ECT practice in Central-Eastern Europe. Systematic literature search was undertaken using the Medline, PSYCHINFO and EMBASE databases covering the period between January 2000 and December 2013. Relevant publications were found from the following countries: Bulgaria, Croatia, Czech Republic, Estonia, Hungary, Latvia, Lithuania, Poland, Romania, Serbia, Slovakia, Ukraine, but none from Albania and Moldova...
June 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28626273/combined-antipsychotics-and-electroconvulsive-therapy-in-an-acutely-psychotic-patient-with-treatment-resistant-schizophrenia
#8
Ruth Rayikanti, Iga Lentowicz, Badari Birur, Li Li
Treatment of patients with Treatment-resistant Schizophrenia (TRS), who fail to respond to multiple antipsychotic trials, including clozapine (CLZ), is challenging. Several alternative strategies are reported in studies, one of which includes augmenting antipsychotics (AP) with Electroconvulsive therapy (ECT). We discuss a case of an acutely psychotic patient with TRS who responded effectively and sustained remission to this strategy which was ECT combined with two AP, CLZ and aripiprazole. Notable improvement in clinical and cognitive outcomes was seen with just five right unilateral ECT sessions, CLZ titrated up to 62...
May 15, 2017: Psychopharmacology Bulletin
https://www.readbyqxmd.com/read/28610803/catatonia-is-not-schizophrenia-and-it-is-treatable
#9
Francisco J Appiani, Gonzalo S Castro
Catatonia is a cluster of motor features that appears in many recognized psychiatric illnesses, that according to the DSM-5 it is not linked as a subtype to schizophrenia anymore. The classic signs are mutism, a rigid posture, fixed staring, stereotypic movements, and stupor, which are all part of a broad psychopathology that may be found in affective, thought, neurological, toxic, metabolic and immunological disorders. Despite the many etiologies, catatonia may be a life-threatening condition with a specific treatment...
June 10, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28560267/electroconvulsive-therapy-induced-brain-functional-connectivity-predicts-therapeutic-efficacy-in-patients-with-schizophrenia-a-multivariate-pattern-recognition-study
#10
Peng Li, Ri-Xing Jing, Rong-Jiang Zhao, Zeng-Bo Ding, Le Shi, Hong-Qiang Sun, Xiao Lin, Teng-Teng Fan, Wen-Tian Dong, Yong Fan, Lin Lu
Previous studies suggested that electroconvulsive therapy can influence regional metabolism and dopamine signaling, thereby alleviating symptoms of schizophrenia. It remains unclear what patients may benefit more from the treatment. The present study sought to identify biomarkers that predict the electroconvulsive therapy response in individual patients. Thirty-four schizophrenia patients and 34 controls were included in this study. Patients were scanned prior to treatment and after 6 weeks of treatment with antipsychotics only (n = 16) or a combination of antipsychotics and electroconvulsive therapy (n = 13)...
2017: NPJ Schizophrenia
https://www.readbyqxmd.com/read/28543089/treatments-for-people-living-with-schizophrenia-in-sub-saharan-africa-an-adapted-realist-review
#11
REVIEW
S Chidarikire, M Cross, I Skinner, M Cleary
AIM: To identify the treatments and interventions available and their impact on people living with schizophrenia in Sub-Saharan Africa. BACKGROUND: Help-seeking behaviour and the choice of treatment are largely influenced by socio-cultural factors and beliefs about the causes of mental illness. This review addresses the gap in knowledge regarding the treatment options available to people living with schizophrenia in Sub-Saharan Africa. DESIGN: Adapted realist literature review...
May 25, 2017: International Nursing Review
https://www.readbyqxmd.com/read/28463343/biological-treatment-of-acute-agitation-or-aggression-with-schizophrenia-or-bipolar-disorder-in-the-inpatient-setting
#12
Christoph U Correll, Xin Yu, Yutao Xiang, John M Kane, Prakash Masand
BACKGROUND: Schizophrenia and bipolar disorders are chronic illnesses that commonly present with symptoms of acute agitation and aggression. These symptoms must be managed rapidly to prevent potential harm to the patient and others, including their caregivers, peers, and health care workers. A number of treatment options are available to clinicians to manage acute agitation and aggression, including non-pharmacologic behavioral and environmental de-escalation strategies, as well as biological treatment options such as pharmacologic agents and electroconvulsive therapy...
May 2017: Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists
https://www.readbyqxmd.com/read/28406327/key-updates-in-the-clinical-application-of-electroconvulsive-therapy
#13
Richard D Weiner, Irving M Reti
ECT is the oldest and most effective therapy available for the treatment of severe major depression. It is highly effective in individuals with treatment resistance and when a rapid response is required. However, ECT is associated with memory impairment that is the most concerning side-effect of the treatment, substantially contributing to the controversy and stigmatization surrounding this highly effective treatment. There is overwhelming evidence for the efficacy and safety of an acute course of ECT for the treatment of a severe major depressive episode, as reflected by the recent FDA advisory panel recommendation to reclassify ECT devices from Class III to the lower risk category Class II...
April 2017: International Review of Psychiatry
https://www.readbyqxmd.com/read/28367711/improvement-of-cycloid-psychosis-following-electroconvulsive-therapy
#14
Jonas Holm, Ole Brus, Ullvi Båve, Mikael Landen, Johan Lundberg, Pia Nordanskog, Lars von Knorring, Axel Nordenskjöld
BACKGROUND: The treatment of choice for cycloid psychosis has traditionally been electroconvulsive therapy (ECT), but there is a lack of studies on its effectiveness. AIMS: The primary aim of this register study was to determine the rates of remission and response after ECT for cycloid psychosis. The secondary aim was to examine possible predictors of outcome. METHODS: Data were obtained from the National Quality Register for ECT in Sweden...
April 3, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28342141/total-tau-and-phosphorylated-tau-protein-serum-levels-in-patients-with-schizophrenia-compared-with-controls
#15
Ömer Faruk Demirel, Ihsan Cetin, Şenol Turan, Nazım Yıldız, Tarık Sağlam, Alaattin Duran
Tau protein is located in the axons of neurons and in Alzheimer Disease, is abnormally phosphorylated and aggregates into paired helical filaments (neurofibrillary tangles) reflecting the degree of neurofibrillary pathology and neurodegeneration. Although tau and phosphorylated tau (p-Tau) pathology is a hallmark for dementia, few studies were performed in patients of schizophrenia. This preliminary serum study was designed to compare serum total tau and p-Tau levels of schizophrenia patients with healthy controls...
March 25, 2017: Psychiatric Quarterly
https://www.readbyqxmd.com/read/28297593/clinical-effectiveness-and-cognitive-impact-of-electroconvulsive-therapy-for-schizophrenia-a-large-retrospective-study
#16
Tyler S Kaster, Zafiris J Daskalakis, Daniel M Blumberger
OBJECTIVE: To determine the clinical effectiveness and cognitive impact of electroconvulsive therapy (ECT) in a large clinical sample of patients with schizophrenia and explore factors associated with treatment response and transient cognitive impairment. METHODS: We examined the clinical records of 144 patients with a DSM-IV diagnosis of schizophrenia or schizoaffective disorder who were treated at an academic mental health hospital from October 2009 to August 2014...
April 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28220613/comparison-of-treatment-patterns-in-schizophrenia-between-china-and-japan-2001-2009
#17
Yu-Tao Xiang, Takahiro A Kato, Taishiro Kishimoto, Gabor S Ungvari, Helen F K Chiu, Tian-Mei Si, Shu-Yu Yang, Senta Fujii, Chee H Ng, Naotaka Shinfuku
INTRODUCTION: To date no study has compared the treatment patterns for schizophrenia specifically between China and Japan. This study examined the cross-national differences in the use of psychotropic drugs and electroconvulsive therapy (ECT) in schizophrenia. METHOD: Data on 3248 schizophrenia inpatients (n = 1524 in China and n = 1724 in Japan) were collected by either chart review or interviews during the designated 3 study periods between 2001 and 2009. Patients' socio-demographic and clinical characteristics, prescriptions of psychotropic drugs, and ECT use were recorded using a standardized protocol and data collection procedure...
February 20, 2017: Asia-Pacific Psychiatry: Official Journal of the Pacific Rim College of Psychiatrists
https://www.readbyqxmd.com/read/28211248/anesthetic-considerations-for-pediatric-electroconvulsive-therapy
#18
REVIEW
Andrew D Franklin, Jenna H Sobey, Eric T Stickles
Electroconvulsive therapy is being used more frequently in the treatment of many chronic and acute psychiatric illnesses in children. The most common psychiatric indications for pediatric electroconvulsive therapy are refractory depression, bipolar disorder, schizophrenia, catatonia, and autism. In addition, a relatively new indication is the treatment of pediatric refractory status epilepticus. The anesthesiologist may be called upon to assist in the care of this challenging and vulnerable patient population...
May 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28162976/neuromodulation-in-response-to-electroconvulsive-therapy-in-schizophrenia-and-major-depression
#19
Philipp Arthur Thomann, Robert Christian Wolf, Henrike Maria Nolte, Dusan Hirjak, Stefan Hofer, Ulrich Seidl, Malte Sebastian Depping, Bram Stieltjes, Klaus Maier-Hein, Fabio Sambataro, Torsten Wüstenberg
BACKGROUND: Electroconvulsive therapy (ECT) is one of the most effective treatments in severe and treatment-resistant major depressive disorder (MDD). ECT has been also shown to be effective in schizophrenia (SZ), particularly when rapid symptom reduction is needed or in cases of resistance to drug-treatment. However, its precise mechanisms of action remain largely unknown. OBJECTIVE/HYPOTHESIS: This study examined whether ECT exerts disorder-specific or unspecific modulation of brain structure and function in SZ and MDD...
May 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28152470/effectiveness-of-electroconvulsive-therapy-in-patients-with-treatment-resistant-schizophrenia-a-retrospective-study
#20
Sandeep Grover, Subho Chakrabarti, Nandita Hazari, Ajit Avasthi
This study aimed to evaluate the effectiveness of electroconvulsive therapy (ECT) among patients with treatment resistant schizophrenia (TRS). Records of patients who had received ECT were reviewed to identify patients with TRS who were administered ECT in combination with clozapine. Socio-demographic, clinical data and ECT details were extracted. The most common diagnosis was of paranoid schizophrenia (49%) followed by undifferentiated schizophrenia (36%). A-fifth (22%) of the patients were judged to have poor response to clozapine...
March 2017: Psychiatry Research
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