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https://www.readbyqxmd.com/read/27926887/the-application-of-genomics-in-diabetes-barriers-to-discovery-and-implementation
#1
James S Floyd, Bruce M Psaty
The emerging availability of genomic and electronic health data in large populations is a powerful tool for research that has drawn interest in bringing precision medicine to diabetes. In this article, we discuss the potential application of genomics to the prediction, prevention, and treatment of diabetes, and we use examples from other areas of medicine to illustrate some of the challenges involved in conducting genomics research in human populations and implementing findings in practice. At this time, a major barrier to the application of genomics in diabetes care is the lack of actionable genomic findings...
November 2016: Diabetes Care
https://www.readbyqxmd.com/read/27926447/motivation-and-attention-following-hemispheric-stroke
#2
E Olgiati, C Russell, D Soto, P Malhotra
Spatial neglect (SN) is an extremely common disorder of attention; it is most frequently a consequence of stroke, especially to the right cerebral hemisphere. The current view of SN is that it is not a unitary deficit but a multicomponent syndrome. Crucially, it has been repeatedly shown that it has a considerable negative impact on rehabilitation outcome. Although a number of behavioral and pharmacological therapies have been developed, none of these appears to be applicable to all patients with SN or has proved unequivocally successful in clinical trials...
2016: Progress in Brain Research
https://www.readbyqxmd.com/read/27925776/providers-and-administrators-perceptions-of-complementary-and-integrative-health-practices-across-the-veterans-health-administration
#3
Carol E Fletcher, Allison R Mitchinson, Erika Trumble, Daniel B Hinshaw, Jeffery A Dusek
OBJECTIVES: Use of complementary and integrative health (CIH) therapies is being promoted by the Veterans Health Administration (VA), but promotion may not equate to adoption. The purpose of this study was to explore whether perceptions regarding CIH at one VA medical center (VAMC) were similar to perceptions from a sample of other VAMCs. DESIGN: This article reports a subset of qualitative findings from a mixed-methods study. SETTING/PARTICIPANTS: Sites were recruited through a VA-wide CIH listserver...
December 7, 2016: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/27925606/increasing-awareness-and-acceptance-through-mindfulness-and-somatic-education-movements
#4
Paulo Vicente Bloise, Mário César Rezende Andrade, Hans Machado, Sérgio Baxter Andreoli
Context • The main feature of mindfulness-based interventions (MBI) is the encouragement of present moment awareness and of self-regulation, which are associated with health benefits. Meditating with the body in movement has been referred to as one of the most accessible ways of reaching such awareness. An MBI program, Mindfulness and Movements of Integration (MMI), has the same structure as mindfulness-based stress reduction (MBSR) but puts more emphasis on the body and uses somatic education (SE) movements instead of yoga postures...
October 2016: Advances in Mind-body Medicine
https://www.readbyqxmd.com/read/27925451/improving-access-and-systems-of-care-for-evidence-based-childhood-obesity-treatment-conference-key-findings-and-next-steps
#5
REVIEW
Denise E Wilfley, Amanda E Staiano, Myra Altman, Jeanne Lindros, Angela Lima, Sandra G Hassink, William H Dietz, Stephen Cook
OBJECTIVE: To improve systems of care to advance implementation of the U.S. Preventive Services Task Force recommendations for childhood obesity treatment (i.e., clinicians offer/refer children with obesity to intensive, multicomponent behavioral interventions of >25 h over 6 to 12 months to improve weight status) and to expand payment for these services. METHODS: In July 2015, 43 cross-sector stakeholders attended a conference supported by the Agency for Healthcare Research and Quality, American Academy of Pediatrics Institute for Healthy Childhood Weight, and The Obesity Society...
December 7, 2016: Obesity
https://www.readbyqxmd.com/read/27925425/preventing-acute-care-associated-venous-thromboembolism-in-adult-and-pediatric-patients-across-a-large-healthcare-system
#6
REVIEW
Timothy I Morgenthaler, Vilmarie Rodriguez
BACKGROUND: Although effective methods for venous thromboembolism prophylaxis (VTE-P) have been known for decades, reliable implementation has been challenging. OBJECTIVE: Develop reliable VTE-P systems for adult and for pediatric patients to reduce preventable venous thromboembolism (VTE). DESIGN: We used a discovery and diffusion system to first develop an effective system in 1 hospital location, and then spread the principle best practices across the entire 22-hospital system...
December 2016: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/27925422/preventing-hospital-acquired-venous-thromboembolism-improving-patient-safety-with-interdisciplinary-teamwork-quality-improvement-analytics-and-data-transparency
#7
REVIEW
Anneliese M Schleyer, Ellen Robinson, Roxana Dumitru, Mark Taylor, Kimberly Hayes, Ronald Pergamit, Daphne M Beingessner, Mark C Zaros, Joseph Cuschieri
BACKGROUND: Hospital-acquired venous thromboembolism (HA-VTE) is a potentially preventable cause of morbidity and mortality. Despite high rates of venous thromboembolism (VTE) prophylaxis in accordance with an institutional guideline, VTE remains the most common hospital-acquired condition in our institution. OBJECTIVE: To improve the safety of all hospitalized patients, examine current VTE prevention practices, identify opportunities for improvement, and decrease rates of HA-VTE...
December 2016: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/27925377/how-many-research-nurses-for-how-many-clinical-trials-in-an-oncology-setting-definition-of-the-nursing-time-required-by-clinical-trial-assessment-tool-ntrct-at
#8
Alessandra Milani, Ketti Mazzocco, Sara Stucchi, Giorgio Magon, Gabriella Pravettoni, Claudia Passoni, Chiara Ciccarelli, Alessandra Tonali, Teresa Profeta, Luisa Saiani
Few resources are available to quantify clinical trial-associated workload, needed to guide staffing and budgetary planning. The aim of the study is to describe a tool to measure clinical trials nurses' workload expressed in time spent to complete core activities. Clinical trials nurses drew up a list of nursing core activities, integrating results from literature searches with personal experience. The final 30 core activities were timed for each research nurse by an outside observer during daily practice in May and June 2014...
December 7, 2016: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/27925142/dg-connect-funded-projects-on-information-and-communication-technologies-ict-for-old-age-people-beyond-silos-carewell-and-smartcare
#9
W Keijser, E de Manuel-Keenoy, M d'Angelantonio, P Stafylas, P Hobson, G Apuzzo, M Hurtado, J Oates, J Bousquet, A Senn
Information and communication technologies (ICT) are promising for the long-term care of older and frequently frail people. These innovations can improve health outcomes, quality of life and efficiency of care processes, while supporting independent living. However, they may be disruptive innovations. As all European member states are facing an increasing complexity of health and social care, good practices in ICT should be identified and evaluated. Three projects funded by DG CNECT are related to Active and Healthy Ageing (AHA) and frailty: (i) BeyondSilos, dealing with independent living and integrated services, (ii) CareWell, providing integrated care coordination, patient empowerment and home support and (iii) SmartCare, proposing a common set of standard functional specifications for an ICT platform enabling the delivery of integrated care to older patients...
2016: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/27925104/epistemology-of-nursing-care-a-reflection-on-its-foundations
#10
Márcia Eller Miranda Salviano, Prince Daiane Felizardo Silva Nascimento, Mariane Andreza de Paula, Carolina Santiago Vieira, Susiane Sucasas Frison, Mariana Almeida Maia, Kleyde Ventura Souza, Eline Lima Borges
Objective: to reflect on nursing care and its epistemology from its historical, theoretical, philosophical, spiritual dimensions and as a social practice. Method: discussions originated in the discipline "Epistemology of caring", from the graduate nursing program of the School of Nursing, Federal University of Minas Gerais, and in critical analysis of nursing literature together with the professional practice of the authors. Results: we identified the necessity of developing a critical conscience on health care provision, research, and teaching, as well as on challenges in maintaining high standards of working interpersonal relationships, which has a profound impact on population health...
November 2016: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/27925099/care-of-the-self-and-power-relations-female-nurses-taking-care-of-other-women
#11
Ana Renata Moura Rabelo, Kênia Lara Silva
Objective: to analyze the care of self of female nurses and the power relations established by them in the care of other women. Method: integrative review of literature published between 2005 and 2015. There were 25 publications in the sample. Results: qualitative state of the art with reference domain of a liberating perspective, based on humanization, autonomy and empowerment as a risk reduction strategy in the practice of care to women...
November 2016: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/27924997/characterization-of-normal-and-freeze-thawed-tissues-in-vitro-through-the-ultrasonic-integrated-backscatter
#12
L Sheng, P Yang, Z He, G Wang, J Luo, J Liu
BACKGROUND: The ultrasound guidance of cryotherapy could be improved if changes of tissue characterization parameters during freezing could be used to monitor freezing patterns and estimate the postoperative effects after surgery. OBJECTIVE: The ultrasonic integrated backscatter analysis holds promise as an effective method for signal analysis and characterization of thawed tissues. MATERIALS AND METHODS: The ultrasonic integrated backscatter has been found to be an important parameter for describing the ultrasonic scattering and characterization of biological tissues...
September 2016: Cryo Letters
https://www.readbyqxmd.com/read/27924939/subwavelength-insb-based-slot-wavguides-for-thz-transport-concept-and-practical-implementations
#13
Youqiao Ma, Jun Zhou, Jaromír Pištora, Mohamed Eldlio, Nghia Nguyen-Huu, Hiroshi Maeda, Qiang Wu, Michael Cada
Seeking better surface plasmon polariton (SPP) waveguides is of critical importance to construct the frequency-agile terahertz (THz) front-end circuits. We propose and investigate here a new class of semiconductor-based slot plasmonic waveguides for subwavelength THz transport. Optimizations of the key geometrical parameters demonstrate its better guiding properties for simultaneous realization of long propagation lengths (up to several millimeters) and ultra-tight mode confinement (~λ(2)/530) in the THz spectral range...
December 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27924347/preprocessing-structured-clinical-data-for-predictive-modeling-and-decision-support-a-roadmap-to-tackle-the-challenges
#14
José Carlos Ferrão, Mónica Duarte Oliveira, Filipe Janela, Henrique M G Martins
BACKGROUND: EHR systems have high potential to improve healthcare delivery and management. Although structured EHR data generates information in machine-readable formats, their use for decision support still poses technical challenges for researchers due to the need to preprocess and convert data into a matrix format. During our research, we observed that clinical informatics literature does not provide guidance for researchers on how to build this matrix while avoiding potential pitfalls...
December 7, 2016: Applied Clinical Informatics
https://www.readbyqxmd.com/read/27923779/a-multidisciplinary-model-to-guide-employment-outcomes-among-people-living-with-spinal-cord-injuries-in-south-africa-a-mixed-methods-study-protocol
#15
Ntsikelelo Pefile, Joyce Mothabeng, Saloshni Naidoo
BACKGROUND: Spinal cord injury (SCI) often results in complete or partial loss of functioning of the upper and/or lower limbs, leading to the affected individual experiencing difficulties in performing activities of daily living. This results in reduced participation in social, religious, recreational, and economic activities (employment). The South Africa legal framework promotes the employment and assistance of people with disabilities. However, rehabilitation interventions focus mainly on impairments and activity limitations, with few attempts to prepare those with SCI to return to gainful employment...
December 6, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27923517/sustainability-of-terraced-paddy-fields-in-traditional-satoyama-landscapes-of-japan
#16
Katsue Fukamachi
Terraced paddy fields are essential components of the traditional cultural landscape of Japan, the satoyama landscape. They have been sustainably cultivated in a variety of ecological and social environments through time, and are highly valued as local resources with multiple functions. This paper reviews the recent nationwide movement for conservation of satoyama landscapes and shows that over the last decades, the government has increasingly created policies based on national regulation or international frameworks that concern the culture and environment in rural areas...
December 3, 2016: Journal of Environmental Management
https://www.readbyqxmd.com/read/27923451/microrna-guided-diagnostics-in-clinical-samples
#17
REVIEW
Dakota Gustafson, Kathrin Tyryshkin, Neil Renwick
miRNA-guided diagnostics is a powerful molecular approach for evaluating clinical samples through miRNA detection and/or visualization. To date, this approach has been successfully used to diagnose, manage, and/or monitor a wide range of neoplastic and non-neoplastic diseases. Despite the promise of miRNA-guided diagnostics, particularly in the field of minimally invasive biomarkers, several knowledge and practical issues confound or hinder translation into routine clinical practice including: miRNA sequence database errors, suboptimal RNA extraction methods, detection assay variability, a vast array of online resources for bioinformatic analyses, and non-standardized statistical analyses for miRNA clinical testing...
October 2016: Best Practice & Research. Clinical Endocrinology & Metabolism
https://www.readbyqxmd.com/read/27923380/quality-evaluation-of-commercially-available-male-condoms-in-rio-de-janeiro-brazil-2009-2011
#18
Janete Teixeira Duarte, Antonio Eugenio C C de Almeida, Shirley de Mello Pereira Abrantes
BACKGROUND: The increased incidence of sexually transmitted infections (STIs) in Brazil represents a significant public health issue. This issue has raised awareness among health authorities regarding the quality of condoms. In Brazil, male condoms need to be certified. The certification process evaluates in detail the manufacturing and quality of the final product; however, post-market surveillance is not part of the normal certification practice. METHODS: From 2009 to 2011, we evaluated 20 male condoms brands per lot of 8 manufactures-both domestic and imported-marketed in Rio de Janeiro, Brazil...
December 7, 2016: Reproductive Health
https://www.readbyqxmd.com/read/27923356/metric-properties-of-the-prescribe-healthy-life-screening-questionnaire-to-detect-healthy-behaviors-a-cross-sectional-pilot-study
#19
Paola Bully, Alvaro Sanchez, Gonzalo Grandes, Haizea Pombo, Ma Soledad Arietalenizbeaskoa, Veronica Arce, Catalina Martinez
BACKGROUND: Feasible and valid assessment of healthy behaviors is the first step for integrating health promotion in routine primary care. Therefore, the aim of this study was to develop and evaluate the validity and reliability of the "prescribe healthy life" screening questionnaire, a brief tool for detecting physical activity levels, consumption of fruit and vegetables, tobacco use and patients' compliance with minimal recommendations. METHODS: An observational cross-sectional study to determine the reliability and validity of this questionnaire by means of mixed (qualitative and quantitative) methods...
December 7, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27923327/formation-of-nanofibrous-matrices-3d-scaffolds-and-microspheres-from-theory-to-practice
#20
Chi Ma, Xiaohua Liu
Nanofibrous architecture presents unique biophysical cues to facilitate cellular responses and is considered an indispensable feature of a biomimetic three-dimensional (3D) scaffold and cell carrier. While electrospinning is a widely used method to prepare natural extracellular matrix-like nanofibers, it faces significant challenges to incorporate nanofibrous architecture into well-defined macroporous 3D scaffolds or injectable microspheres. Here we report a non-electrospinning approach that is generally effective at generating nanofibers from a variety of synthetic and natural biodegradable polymers and integrating these nanofibers into (1) 3D scaffolds with constructive geometry and designed internal macropore structures; and (2) injectable microspheres...
December 6, 2016: Tissue Engineering. Part C, Methods
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