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https://www.readbyqxmd.com/read/28631132/adaptive-biochemical-and-physiological-responses-of-eriobotrya-japonica-to-fluoride-air-pollution
#1
Nada Elloumi, Mohamed Zouari, Imed Mezghani, Ferjani Ben Abdallah, Steve Woodward, Monem Kallel
The biochemical and physiological effects of fluoride were investigated in loquat trees (Eriobotrya japonica) grown in the vicinity of a phosphate fertilizer plant in Tunisia. Photosynthetic rate (Pn), stomatal conductance (Gs), transpiration rate (E), superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) activities were assessed; along with photosynthetic pigments, lipid peroxidation, electrolytic leakage (EL) and total phenolic contents in foliage and roots of trees at different distances from the phosphate fertilizer plant...
June 19, 2017: Ecotoxicology
https://www.readbyqxmd.com/read/28626957/graves-disease-with-severe-neutropenia-any-clues
#2
Mohamed Osama Hegazi, Ammar Almansour, Abdallah Nawara
In volume 85, issue 6 of "Clinical Endocrinology", Aggarwal, et al. published a study titled "Treatment of Hyperthyroidism With Antithyroid Drugs Corrects Mild Neutropenia in Graves' Disease". The authors treated Graves' disease (GD) with mild neutropenia using a thionamide anti-thyroid drug (ATD). From that study we conclude that neutropenia is not uncommon in association with GD and accounts for 14% of cases, and that mild neutropenia does not preclude the use of ATDs. This article is protected by copyright...
June 19, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28625341/efficacy-and-toxicity-of-metronomic-chemotherapy-in-metastatic-breast-cancer-egyptian-experience
#3
Marwa Mahmoud Hussein, Rabab Mohamed Gaafar, Ahmed Mostafa Abdel-Warith, Wafaa Abdallah Ahmed, Nasr Mohamed Ali Allahloubi, Salem Eid Salem, Ibrahem Mohamed Abdel-Salam
BACKGROUND: Metronomic chemotherapy (MC) has shown efficacy in patients with metastatic breast cancer (MBC). We therefore tested the efficacy and toxicity of MC in pretreated MBC. PATIENTS AND METHODS: This prospective phase II study included 50 patients with heavily pretreated MBC who received MC in the form of continuous oral cyclophosphamide 50 mg/day and oral methotrexate 2.5 mg twice per day on days 1 and 2 every week. The primary end point was progression-free survival (PFS), whereas the secondary end points were response rate, overall survival (OS), and safety...
May 8, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28619208/inconclusive-evidence-on-using-antibiotic-prophylaxis-before-dental-procedures-to-prevent-infective-endocarditis
#4
Mohamed-Nur Abdallah
No abstract text is available yet for this article.
June 13, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28595559/25-hydroxyvitamin-d-correlation-with-prolactin-levels-and-adenoma-size-in-female-patients-with-newly-diagnosed-prolactin-secreting-adenoma
#5
Mohamed M Aboelnaga, N Abdallah, M El Shaer
OBJECTIVE: The present research explored the relationship of vitamin D status with prolactin levels and adenoma size in female patients with newly diagnosed prolactinoma and determination of hypovitaminosis D prevalence among female patients with prolactinoma. PATIENTS AND METHODS: We enrolled 67 female patients with newly diagnosed prolactinoma (41 with micro adenoma and 26 with macro adenoma) in this case-control study at the time of presentation. We selected a Control Group of 45 female subjects who were matched according to age, weight, height, body mass index and waist circumference...
June 9, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/28579111/clinical-features-and-prognosis-of-infective-endocarditis-in-children-insights-from-a-tunisian-multicentre-registry
#6
Walid Jomaa, Imen Ben Ali, Dorra Abid, Samia Hajri Ernez, Leila Abid, Faten Triki, Samir Kammoun, Anissa Gharbi, Oussama Ben Rejeb, Abdallah Mahdhaoui, Gouider Jeridi, Mohamed A Azaiez, Aymen El Hraiech, Khaldoun Ben Hamda, Faouzi Maatouk
BACKGROUND: Infective endocarditis (IE) is a rare condition in the paediatric setting. No data on the epidemiology and prognosis of IE in children are available from North African countries. AIM: To investigate the epidemiological profile and prognosis of IE in children in Tunisia. METHODS: All patients aged≤18 years presenting with IE in three Tunisian tertiary care centres between January 1997 and September 2013 were included. Clinical features and 30-day and 6-month mortality rates were studied...
May 31, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28577891/treatment-of-posterior-cruciate-ligament-tibial-avulsion-by-a-minimally-invasive-open-posterior-approach
#7
Ahmed Abdelbadie Abdallah, Mohammed S Arafa
OBJECTIVE: To assess the surgical technique and report the outcomes following fixation of PCL bony avulsions through mini-invasive posterior knee approach as described by Burks and Schaffer. METHODS: From June 2012 to July 2015, 27 patients enrolled in the study (21 males and 6 females). Fixation of tibial PCL avulsion fractures was done with one or two cannulated screws, or sutures through Burks and Schaffer's approach. The mean interval before surgery was 16days (1-70) ...
May 26, 2017: Injury
https://www.readbyqxmd.com/read/28561993/removable-partial-denture-alloys-processed-by-laser-sintering-technique
#8
Omar Alageel, Mohamed-Nur Abdallah, Ammar Alsheghri, Jun Song, Eric Caron, Faleh Tamimi
Removable partial dentures (RPDs) are traditionally made using a casting technique. New additive manufacturing processes based on laser sintering has been developed for quick fabrication of RPDs metal frameworks at low cost. The objective of this study was to characterize the mechanical, physical, and biocompatibility properties of RPD cobalt-chromium (Co-Cr) alloys produced by two laser-sintering systems and compare them to those prepared using traditional casting methods. The laser-sintered Co-Cr alloys were processed by the selective laser-sintering method (SLS) and the direct metal laser-sintering (DMLS) method using the Phenix system (L-1) and EOS system (L-2), respectively...
May 31, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28555171/perforated-duodenal-diverticulum-treated-conservatively-another-two-successful-cases
#9
Jad A Degheili, Mohammed H Abdallah, Ali A Haydar, Ahmad Moukalled, Ali H Hallal
Diverticula of the duodenum proceed those of the colon in respect to frequency of location. Incidence at times of autopsy ranges from 15 to 23%. Despite the fact that more than 90% of duodenal diverticulum cases are asymptomatic, complications if they do occur can be calamitous. Perforation is one of these rare complications. Surgical intervention has always been the mainstay for symptomatic/complicated duodenal diverticula, but with the advancement of imaging, medical treatment, and proper intensive observation, conservative treatment came forth...
2017: Case Reports in Surgery
https://www.readbyqxmd.com/read/28549794/intensity-modulated-proton-therapy-and-osteoradionecrosis-in-oropharyngeal-cancer
#10
Wencheng Zhang, Xiaodong Zhang, Pei Yang, Pierre Blanchard, Adam S Garden, Brandon Gunn, C David Fuller, Mark Chambers, Katherine A Hutcheson, Rong Ye, Stephen Y Lai, Mohamed Abdallah Sherif Radwan, X Ron Zhu, Steven J Frank
PURPOSE: We compared mandibular doses and osteoradionecrosis in patients with oropharyngeal cancer after intensity-modulated radiation therapy (IMRT) or intensity-modulated proton therapy (IMPT). METHODS AND MATERIALS: We identified 584 patients who received definitive radiotherapy for oropharyngeal cancer from January 2011 through June 2014 at MD Anderson Cancer Center (534 IMRT and 50 IMPT). The dosimetric variables and osteoradionecrosis were compared with Chi-square test or Fisher's exact test...
May 23, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28526989/first-molecular-detection-and-characterization-of-hepatozoon-and-sarcocystis-spp-in-field-mice-and-voles-from-japan
#11
Mohamed Abdallah Mohamed Moustafa, Michito Shimozuru, Wessam Mohamed, Kyle Rueben Taylor, Ryo Nakao, Mariko Sashika, Toshio Tsubota
Sarcocystis and Hepatozoon species are protozoan parasites that are frequently detected in domestic and wild animals. Rodents are considered common intermediate and paratenic hosts for several Sarcocystis and Hepatozoon species. Here, blood DNA samples from a total of six rodents, including one Myodes rutilus, one Myodes rufocanus, and four Apodemus speciosus, collected from Hokkaido, Japan, were shown by conventional PCR of the 18S ribosomal RNA (rRNA) gene to contain Sarcocystis and Hepatozoon DNA. Sequencing of the DNA detected one Sarcocystis sp...
May 19, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28525835/emerging-and-legacy-flame-retardants-in-uk-human-milk-and-food-suggest-slow-response-to-restrictions-on-use-of-pbdes-and-hbcdd
#12
Fang Tao, Mohamed Abou-Elwafa Abdallah, Danielle C Ashworth, Philippa Douglas, Mireille B Toledano, Stuart Harrad
The legacy flame retardants (LFRs) polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecane (HBCDD), together with six emerging flame retardants (EFRs) were measured in United Kingdom (UK) human milk collected in 2010 (n=25) and 2014-15 (n=10). These data are the first report of the presence of EFRs in UK human milk. The most abundant EFR was β-tetrabromoethylcyclohexane (DBE-DBCH) (average=2.5ng/g lw; geometric mean=1.5ng/g lw), which is comparable to the concentrations of the most abundant LFRs i...
May 16, 2017: Environment International
https://www.readbyqxmd.com/read/28483280/stacking-cyclodextrin-microchip-electrokinetic-chromatographic-determination-of-gabapentinoid-drugs-in-pharmaceutical-and-biological-matrices
#13
Abdallah M Zeid, Noritada Kaji, Jenny Jeehan M Nasr, Fathalla F Belal, Yoshinobu Baba, Mohamed I Walash
A facile, rapid, and highly sensitive microchip-based electrokinetic chromatographic method was developed for the simultaneous analysis of two gabapentinoid drugs, gabapentin (GPN) and pregabalin (PGN). Both drugs were first reacted with 4-fluoro-7-nitro-2,1,3-benzoxadiazole (NBD-F) via nucleophilic substitution reactions to yield highly fluorescent products with λex/em 470/540nm. Analyses of both fluorescently labeled compounds were achieved within 200s in a poly(methyl methacrylate) (PMMA) microchip with a 30mm separation channel...
April 26, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28480808/impact-of-different-sofosbuvir-based-treatment-regimens-on-the-biochemical-profile-of-chronic-hepatitis-c-genotype-4-patients
#14
Aisha Elsharkawy, Rasha Eletreby, Rabab Fouad, Zeinab Soliman, Mohamed Abdallah, Mohamed Negm, Mohammad Mohey, Gamal Esmat
BACKGROUND: Huge efforts have been made to control chronic HCV in Egypt with introduction of Direct-Acting Antivirals (DAAs). Current study aims at evaluating effect of various DAA regimens on liver biochemical profile and haematological indices during treatment. METHODS: 272 patients with chronic HCV genotype 4 treated by different DAA regimens (SOF/RBV, SOF/DAC ± RBV, SOF/SIM) for a duration of 12 or 24 weeks in Kasr Alainy Viral Hepatitis Center, Cairo University were followed up for serum bilirubin (BIL), albumin (ALB), alanine transaminase (ALT), aspartate aminotransferase (AST), prothrombin concentration, international normalized ratio (INR), and CBC at baseline, week-4 and end of treatment...
May 15, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28464542/quantitative-pretreatment-ct-volumetry-association-with-oncologic-outcomes-in-patients-with-t4a-squamous-carcinoma-of-the-larynx
#15
Jay C Shiao, Abdallah S R Mohamed, Jay A Messer, Katherine A Hutcheson, Jason M Johnson, Heiko Enderling, Mona Kamal, Benjamin W Warren, Brian Pham, William H Morrison, Mark E Zafereo, Amy C Hessel, Stephen Y Lai, Merril S Kies, Renata Ferrarotto, Adam S Garden, Donald F Schomer, G Brandon Gunn, Jack Phan, Steven J Frank, Beth M Beadle, Randal S Weber, Jan S Lewin, David I Rosenthal, Clifton D Fuller
BACKGROUND: The purpose of this study was to determine the impact of CT-determined pretreatment primary tumor volume on survival and disease control in T4a laryngeal squamous cell carcinoma (SCC). METHODS: We retrospectively reviewed 124 patients with T4a laryngeal cancer from 2000-2011. Tumor volume measurements were collected and correlated with outcomes. RESULTS: Five-year overall survival (OS) for patients with tumor volume ≥21 cm(3) treated with larynx preservation (n = 26 of 41) was significantly inferior compared to <21 cm(3) (42% vs 64%, respectively; P = ...
May 2, 2017: Head & Neck
https://www.readbyqxmd.com/read/28458368/synthesis-of-novel-heterocyclic-compounds-incorporate-4-5-6-7-tetrahydrobenzo-b-thiophene-together-with-their-cytotoxic-evaluations
#16
Amira Elsayed Mahmoud Abdallah, Rafat Milad Mohareb, Eid Metwally Khalil, Menna Alla Mohamed Abd Elaleem Elshamy
The 2-amino-3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophene was the key starting compound used to synthesize new thiazole, pyrimidine, pyran, pyridine and thiazine derivatives. The cytotoxicity of the synthesized compounds was studied towards the three cancer cell lines namely MCF-7 (breast adenocarcinoma), NCI-H460 (non-small cell lung cancer) and SF-268 (central nervous system (CNS) cancer) in addition to the normal cell line (WI-38) using doxorubicin as the reference drug. The study showed that compounds 5, 9a, 15b, 17c, 18 and 21b were the most potent compounds...
2017: Chemical & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28454556/molecular-and-epidemiological-characterization-of-hiv-1-subtypes-among-libyan-patients
#17
Mohamed A Daw, Abdallah El-Bouzedi, Mohamed O Ahmed, Aghnyia A Dau
BACKGROUND: The epidemiological and clinical aspects of human immunodeficiency virus subtypes are of great interest worldwide. These subtypes are rarely studied in North African countries. Libya is a large country with the longest coast on the Mediterranean Sea, facing the Southern European countries. Studies on the characterization of HIV-1 subtypes are limited in Libya. This study aimed to determine the magnitude of the HIV problem among the Libyan population and to better understand the genetic diversity and the epidemiologic dynamics of HIV 1, as well as to correlate that with the risk factors involved...
April 28, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28452319/effect-of-elective-percutaneous-coronary-intervention-of-left-anterior-descending-coronary-artery-on-regional-myocardial-function-using-strain-imaging
#18
Gihan Magdy, Mohammed Sadaka, Tarek Elzawawy, Abdallah Elmaghraby
No abstract text is available yet for this article.
March 2017: Atherosclerosis. Supplements
https://www.readbyqxmd.com/read/28446036/fusaripeptide-a-new-antifungal-and-anti-malarial-cyclodepsipeptide-from-the-endophytic-fungus-fusarium-sp
#19
Sabrin R M Ibrahim, Hossam M Abdallah, Ehab S Elkhayat, Nawal M Al Musayeib, Hani Z Asfour, Mohamed F Zayed, Gamal A Mohamed
From the culture of the endophytic fungus Fusarium sp. isolated from the roots of Mentha longifolia L. (Labiatae) growing in Saudi Arabia, a new cyclodepsipeptide, namely fusaripeptide A (1), along with three known compounds adenosine (2), 2[(2-hydroxypropionyl)amino]benzamide (3), and cyclopentanol (4), have been isolated. Their structures were determined, using extensive 1D and 2D NMR and HRESI and GC mass spectral data. That is the first report for the isolation of compound 4 from natural source. In addition, compounds 2 and 3 are reported here for the first time from Fusarium sp...
April 27, 2017: Journal of Asian Natural Products Research
https://www.readbyqxmd.com/read/28437805/anti-inflammatory-antipyretic-and-antinociceptive-effects-of-a-cressa-cretica-aqueous-extract
#20
Heba Mohammed Ibrahim Abdallah, Abdelsamed Ibrahim Elshamy, Abd El-Nasser Gaber El Gendy, Ahmed Mohamed Abd El-Gawad, Elsayed Abouelfotowh Omer, Marinella De Leo, Luisa Pistelli
Cressa cretica is a widely grown halophytic plant traditionally used for the treatment of different ailments. Previous investigations reported its biological activity on a wide spectrum of diseases. In this study, in vivo antinociceptive, anti-inflammatory, and antipyretic activities of C. cretica aqueous extract whole plant were evaluated. In addition, the total polyphenol content, the total flavonoid content, and the chemical characterization of the extract were performed. C. cretica showed writhing inhibition in acetic acid-induced peripheral nociception of 43 and 48 % at doses of 50 and 100 mg/kg, respectively...
April 24, 2017: Planta Medica
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