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https://www.readbyqxmd.com/read/28913730/current-treatment-strategies-for-tricuspid-regurgitation
#1
REVIEW
Mohammed Al-Hijji, Erin A Fender, Abdallah El Sabbagh, David R Holmes
PURPOSE OF REVIEW: Tricuspid regurgitation is common; however, recognition and diagnosis, clinical outcomes, and management strategies are poorly defined. Here, we will describe the etiology and natural history of tricuspid regurgitation (TR), evaluate existing surgical outcomes data, and review the evolving field of percutaneous interventions to treat TR. RECENT FINDINGS: Previously, the only definitive corrective therapy for TR was surgical valve repair or replacement which is associated with significant operative mortality...
September 14, 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28911637/safety-of-frozen-liver-for-human-consumption
#2
Ghada A K Kirrella, Azza M M Deeb, Reda Mohamed Ibrahim Abdallah
The objective of this study was to ensure and evaluate the safety of imported frozen beef liver traded in supermarkets of Kafr El-Sheikh Governorate, Egypt, through detection of Salmonella typhimurium, Salmonella enteritidies, Escherichia coli O157:H7, antibiotic residues, and aflatoxin B1 residue. Fifty samples of imported frozen liver were randomly collected from different shops at Kafr El-Sheikh Governorate for isolation of S. typhimurium, S. enteritidies, and E. coli O157:H7. The results revealed that for both microorganisms 4% of the examined samples presumed to contain Salmonella and E...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28894197/a-multi-institutional-comparison-of-dynamic-contrast-enhanced-magnetic-resonance-imaging-parameter-calculations
#3
Rachel B Ger, Abdallah S R Mohamed, Musaddiq J Awan, Yao Ding, Kimberly Li, Xenia J Fave, Andrew L Beers, Brandon Driscoll, Hesham Elhalawani, David A Hormuth, Petra J van Houdt, Renjie He, Shouhao Zhou, Kelsey B Mathieu, Heng Li, Catherine Coolens, Caroline Chung, James A Bankson, Wei Huang, Jihong Wang, Vlad C Sandulache, Stephen Y Lai, Rebecca M Howell, R Jason Stafford, Thomas E Yankeelov, Uulke A van der Heide, Steven J Frank, Daniel P Barboriak, John D Hazle, Laurence E Court, Jayashree Kalpathy-Cramer, Clifton D Fuller
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) provides quantitative metrics (e.g. K(trans), ve) via pharmacokinetic models. We tested inter-algorithm variability in these quantitative metrics with 11 published DCE-MRI algorithms, all implementing Tofts-Kermode or extended Tofts pharmacokinetic models. Digital reference objects (DROs) with known K(trans) and ve values were used to assess performance at varying noise levels. Additionally, DCE-MRI data from 15 head and neck squamous cell carcinoma patients over 3 time-points during chemoradiotherapy were used to ascertain K(trans) and ve kinetic trends across algorithms...
September 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28893076/seroprevalence-and-risk-factors-for-i-coxiella-burnetii-i-the-causative-agent-of-q-fever-in-the-dromedary-camel-i-camelus-dromedarius-i-population-in-algeria
#4
Mohammed H Benaissa, Samir Ansel, Abdallah Mohamed-Cherif, Karima Benfodil, Djamel Khelef, Curtis R Youngs, Rachid Kaidi, Khatima Ait-Oudhia
Query (Q) fever is a globally distributed zoonotic disease caused by Coxiella burnetii, a bacterial agent for which ruminants are the most prevalent natural reservoir. Data regarding Q fever infection in camels in Algeria are limited. Therefore, a survey to detect seroprevalence of C. burnetii antibodies was conducted among healthy camel populations in a vast area in southeastern Algeria to determine distribution of the Q fever causative organism and to identify risk factors associated with infection. Between January and March 2016, blood samples were collected from 184 camels and serum samples were subsequently analysed using a commercial Enzyme-Linked Immunosorbent Assay (ELISA) kit...
August 31, 2017: Onderstepoort Journal of Veterinary Research
https://www.readbyqxmd.com/read/28888224/long-term-patient-reported-outcomes-following-radiation-therapy-for-oropharyngeal-cancer-cross-sectional-assessment-of-a-prospective-symptom-survey-in-patients-%C3%A2-65%C3%A2-years-old
#5
Salman A Eraj, Mona K Jomaa, Crosby D Rock, Abdallah S R Mohamed, Blaine D Smith, Joshua B Smith, Theodora Browne, Luke C Cooksey, Bowman Williams, Brandi Temple, Kathryn E Preston, Jeremy M Aymar, Neil D Gross, Randal S Weber, Amy C Hessel, Renata Ferrarotto, Jack Phan, Erich M Sturgis, Ehab Y Hanna, Steven J Frank, William H Morrison, Ryan P Goepfert, Stephen Y Lai, David I Rosenthal, Tito R Mendoza, Charles S Cleeland, Kate A Hutcheson, Clifton D Fuller, Adam S Garden, G Brandon Gunn
BACKGROUND: Given the potential for older patients to experience exaggerated toxicity and symptoms, this study was performed to characterize patient reported outcomes in older patients following definitive radiation therapy (RT) for oropharyngeal cancer (OPC). METHODS: Cancer-free head and neck cancer survivors (>6 months since treatment completion) were eligible for participation in a questionnaire-based study. Participants completed the MD Anderson Symptom Inventory-Head and Neck module (MDASI-HN)...
September 9, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28886038/diagnoses-infections-and-injuries-in-northern-syrian-children-during-the-civil-war-a-cross-sectional-study
#6
Gerlant van Berlaer, Abdallah Mohamed Elsafti, Mohammad Al Safadi, Saad Souhil Saeed, Ronald Buyl, Michel Debacker, Atef Redwan, Ives Hubloue
BACKGROUND: The civil war in Syria including the deliberate targeting of healthcare services resulted in a complex humanitarian emergency, seriously affecting children's health. The objectives of this study are to document diagnoses and disease categories in Northern Syrian children after four years of conflict, and to document infectious diseases and injuries in this vulnerable population. METHODS: In a prospective cross-sectional observational sample study conducted in May 2015, healthcare workers registered demographics, comorbidities, and diagnoses (categorised according to the International Classification of Diseases version 10) in children visited at home and in internally displaced persons camps in four Syrian governorates...
2017: PloS One
https://www.readbyqxmd.com/read/28855817/characterization-and-anti-aspergillus-flavus-impact-of-nanoparticles-synthesized-by-penicillium-citrinum
#7
Mohamed A Yassin, Abd El-Rahim M A El-Samawaty, Turki M Dawoud, Omar H Abd-Elkader, Khalid S Al Maary, Ashraf A Hatamleh, Abdallah M Elgorban
This work was conducted to evaluate the ability of grape molding fungus; Penicillium citrinum to synthesize silver nanoparticles (Ag NPs). The potency of biosynthesized Ag NPs was checked against the aflatoxigenic Aspergillus flavus var. columnaris, isolated from sorghum grains. Biosynthesized Ag NPs were characterized and confirmed in different ways. X ray diffraction (XRD), Energy Dispersive Spectroscopy (EDS), Transmission Electron Microscopy (TEM) and optical absorption measurements confirmed the bio-synthesis of Ag NPs...
September 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28854340/sequential-analysis-and-staging-of-a-diethylnitrosamine-induced-hepatocellular-carcinoma-in-male-wistar-albino-rat-model
#8
Abdallah H Fathy, Mohamad Abdel-Monem Bashandy, Samir Ae Bashandy, Ahmed M Mansour, Bakheet Mohammed Elsadek
Hepatocellular carcinoma (HCC) is one of the most life-threatening cancers. The present study was designed to chronologically analyze the HCC chemically induced by diethylnitrosamine (DEN) in male Wistar rats during 27 weeks. DEN was given to rats in drinking water (100 mg/L) to induce HCC. In the present study, the DEN administered groups recorded dramatic results in the tumor markers, oxidative stress, lipid profile, liver function and hematological parameters at all intervals when compared to their corresponding values in the control groups...
August 30, 2017: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/28847134/brominated-flame-retardants-in-black-plastic-kitchen-utensils-concentrations-and-human-exposure-implications
#9
Jiangmeng Kuang, Mohamed Abou-Elwafa Abdallah, Stuart Harrad
Concerns exist that restricted brominated flame retardants (BFRs) present in waste polymers may have, as a result of recycling, inadvertently contaminated items not required to meet flame retardancy regulations (e.g. plastic kitchen utensils). To investigate the extent to which kitchen utensils are contaminated with BFRs and the potential for resultant human exposure, we collected 96 plastic kitchen utensils and screened for Br content using a hand-held X-ray fluorescence (XRF) spectrometer. Only 3 out of 27 utensils purchased after 2011 contained detectable concentrations of Br (≥3μg/g)...
August 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28846412/biotransformation-of-the-flame-retardant-1-2-dibromo-4-1-2-dibromoethyl-cyclohexane-tbech-in-vitro-by-human-liver-microsomes
#10
Khanh-Hoang Nguyen, Mohamed Abou-Elwafa Abdallah, Thomas Moehring, Stuart Harrad
The technical mixture of 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane (TBECH or DBE-DBCH) and the pure β-TBECH isomer were subjected to in vitro biotransformation by human liver microsomes (HLM). After 60 min of incubation, 5 potential metabolites of TBECH were identified in microsomal assays of both the TBECH mixture and β-TBECH using ultraperformance liquid chromatography-Q-Exactive Orbitrap mass spectrometry. These include mono- and dihydroxylated TBECH and mono- and dihydroxylated TriBECH as well as an α-oxidation metabolite bromo-(1,2-dibromocyclohexyl)-acetic acid...
September 7, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28843867/prevalence-of-sexual-dysfunction-in-infertile-versus-fertile-couples
#11
Amir A Gabr, Eman F Omran, Ahmed A Abdallah, Mohamed M Kotb, Eman Z Farid, Amira S Dieb, Doaa S Belal
OBJECTIVES: The primary aim of this study was to test the hypothesis that sexual dysfunction is higher in infertile females in relation to normal healthy women through comparing total and sexual domains scores in both groups. The secondary objectives were: to determine factors affecting occurrence of female sexual dysfunction (FSD) in all sample and to determine factors affecting the different sexual domain scores within the infertile group. STUDY DESIGN: This cross sectional study was done at Cairo University Hospital...
August 19, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28811744/cytogenetic-profile-and-flt3-gene-mutations-of-childhood-acute-lymphoblastic-leukemia
#12
Nawaf Alkhayat, Yasser Elborai, Omer Al Sharif, Mohammad Al Shahrani, Omar Alsuhaibani, Mohammed Awad, Hatem Elghezal, Inesse Ben-Abdallah Bouhajar, Mona Alfaraj, Eman Al Mussaed, Fahad Alabbas, Ghaleb Elyamany
BACKGROUND: Childhood acute lymphoblastic leukemia (ALL) is characterized by recurrent genetic aberrations. The identification of those abnormalities is clinically important because they are considered significant risk-stratifying markers. AIMS: There are insufficient data of cytogenetic profiles in Saudi Arabian patients with childhood ALL leukemia. We have examined a cohort of 110 cases of ALL to determine the cytogenetic profiles and prevalence of FLT3 mutations and analysis of the more frequently observed abnormalities and its correlations to other biologic factors and patient outcomes and to compare our results with previously published results...
2017: Clinical Medicine Insights. Oncology
https://www.readbyqxmd.com/read/28806994/patterns-of-locoregional-failure-following-post-operative-intensity-modulated-radiotherapy-to-oral-cavity-cancer-quantitative-spatial-and-dosimetric-analysis-using-a-deformable-image-registration-workflow
#13
Abdallah S R Mohamed, Andrew J Wong, Clifton D Fuller, Mona Kamal, Gary B Gunn, Jack Phan, William H Morrison, Beth M Beadle, Heath Skinner, Stephen Y Lai, Sean R Quinlan-Davidson, Abdelaziz M Belal, Ahmed G El-Gowily, Steven J Frank, David I Rosenthal, Adam S Garden
BACKGROUND: We sought to identify spatial/dosimetric patterns of failure for oral cavity cancer patients receiving post-operative IMRT (PO-IMRT). METHODS: Two hundred eighty-nine OCC patients receiving PO-IMRT were retrospectively reviewed from 2000 to 2012. Diagnostic CT documenting recurrence (rCT) was co-registered with planning CT (pCT) using a validated deformable image registration software. Manually segmented recurrent gross disease (rGTV) was deformed to co-registered pCTs...
August 15, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28797747/metal-composite-adhesion-based-on-diazonium-chemistry
#14
Yara Oweis, Omar Alageel, Paige Kozak, Mohamed-Nur Abdallah, Jean-Marc Retrouvey, Marta Cerruti, Faleh Tamimi
OBJECTIVE: Composite resins do not adhere well to dental alloys. This weak bond can result in failure at the composite-metal interface in fixed dental prostheses and orthodontic brackets. The aim of this study was to develop a new adhesive, based on diazonium chemistry, to facilitate chemical bonding between dental alloys and composite resin. METHODS: Samples of two types of dental alloys, stainless steel and cobalt chromium were primed with a diazonium layer in order to create a surface coating favorable for composite adhesion...
August 7, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28797467/outcomes-of-oral-cavity-cancer-patients-treated-with-surgery-followed-by-postoperative-intensity-modulated-radiation-therapy
#15
Sean R Quinlan-Davidson, Abdallah S R Mohamed, Jeffrey N Myers, Gary B Gunn, Faye M Johnson, Heath Skinner, Beth M Beadle, Ann M Gillenwater, Jack Phan, Steven J Frank, William N William, Andrew J Wong, Stephen Y Lai, Clifton D Fuller, William H Morrison, David I Rosenthal, Adam S Garden
OBJECTIVES: Although treatment paradigms have not changed significantly, radiotherapy, surgery, and imaging techniques have improved, leading us to investigate oncologic and survival outcomes for oral cavity squamous cell cancer (OCSCC) patients treated with surgery followed by postoperative IMRT. MATERIAL AND METHODS: Records of patients with pathological diagnosis of OCSCC treated between 2000 and 2012 were retrospectively reviewed. Patients' demographic, disease, and treatment criteria were extracted...
September 2017: Oral Oncology
https://www.readbyqxmd.com/read/28776691/three-dimensionally-printed-polyetherketoneketone-scaffolds-with-mesenchymal-stem-cells-for-the-reconstruction-of-critical-sized-mandibular-defects
#16
Michael G Roskies, Dongdong Fang, Mohamed-Nur Abdallah, Andre M Charbonneau, Navi Cohen, Jack O Jordan, Michael P Hier, Alex Mlynarek, Faleh Tamimi, Simon D Tran
OBJECTIVE: Additive manufacturing offers a tailored approach to tissue engineering by providing anatomically precise scaffolds onto which stem cells and growth factors can be supplied. Polyetherketoneketone (PEKK), an ideal candidate biomaterial, is limited by a poor implant-bone interface but can be functionalized with adipose-derived stem cells (ADSC) to promote integration. This in vivo study examined the interaction of a three-dimensional printed PEKK/ADSC implant within the critical-sized mandibular defect in a rabbit model...
August 4, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28774596/patterns-of-failure-guided-biological-target-volume-definition-for-head-and-neck-cancer-patients-fdg-pet-and-dosimetric-analysis-of-dose-escalation-candidate-subregions
#17
Abdallah S R Mohamed, Carlos E Cardenas, Adam S Garden, Musaddiq J Awan, Crosby D Rock, Sarah A Westergaard, G Brandon Gunn, Abdelaziz M Belal, Ahmed G El-Gowily, Stephen Y Lai, David I Rosenthal, Clifton D Fuller, Michalis Aristophanous
BACKGROUND: To identify the radio-resistant subvolumes in pretreatment FDG-PET by mapping the spatial location of the origin of tumor recurrence after IMRT for head-and-neck squamous cell cancer to the pretreatment FDG-PET/CT. METHODS: Patients with local/regional recurrence after IMRT with available FDG-PET/CT and post-failure CT were included. For each patient, both pre-therapy PET/CT and recurrence CT were co-registered with the planning CT (pCT). A 4-mm radius was added to the centroid of mapped recurrence growth target volumes (rGTV's) to create recurrence nidus-volumes (NVs)...
August 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28769010/comparative-genomic-analysis-mers-cov-isolated-from-humans-and-camels-with-special-reference-to-virus-encoded-helicase
#18
Mohamed Alnazawi, Abdallah Altaher, Mahmoud Kandeel
Middle East Respiratory Syndrome Coronavirus (MERS CoV) is a new emerging viral disease characterized by high fatality rate. Understanding MERS CoV genetic aspects and codon usage pattern is important to understand MERS CoV survival, adaptation, evolution, resistance to innate immunity, and help in finding the unique aspects of the virus for future drug discovery experiments. In this work, we provide comprehensive analysis of 238 MERS CoV full genomes comprised of human (hMERS) and camel (cMERS) isolates of the virus...
2017: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28763137/cognitive-function-and-patient-reported-memory-problems-after-radiotherapy-for-cancers-at-the-skull-base-a-cross-sectional-survivorship-study-using-the-telephone-interview-for-cognitive-status-and-the-md-anderson-symptom-inventory-head-and-neck-module
#19
Chase C Hansen, Joshua B Smith, Abdallah S R Mohamed, Collin F Mulcahy, Jeffrey S Wefel, Katherine A Hutcheson, Kelsey Chrane, Jack Phan, Steven J Frank, Adam S Garden, Blaine D Smith, Hillary Eichelberger, Carthal Anderson, Colton McCoy, Marina Horiates, Conner Patrick, Sarah Floris, Chloe French, Beth M Beadle, William H Morrison, Shirley Y Su, Carol M Lewis, Michael E Kupferman, Jason M Johnson, Heath D Skinner, Stephen Y Lai, Ehab Y Hanna, David I Rosenthal, Clifton D Fuller, G Brandon Gunn
BACKGROUND: Using patient-reported and objective assessment tools, we sought to quantify cognitive symptoms and objective cognitive dysfunction in patients irradiated for skull base cancer. METHODS: Participants were assessed using the Telephone Interview for Cognitive Status (TICS) and the MD Anderson Symptom Inventory-Head and Neck module (MDASI-HN), with subsequent analysis. RESULTS: Of the 122 participants analyzed, the majority (63%) had no frank detectable cognitive impairment by TICS, with frank impairment in 6%...
August 1, 2017: Head & Neck
https://www.readbyqxmd.com/read/28757824/effects-of-preincisional-analgesia-with-surgical-site-infiltration-of-ketamine-or-levobupivacaine-in-patients-undergoing-abdominal-hysterectomy-under-general-anesthesia-a-randomized-double-blind-study
#20
Nasr Mahmoud Abdallah, Atef Kamel Salama, Ahmed Mohamed Ellithy
CONTEXT: Postoperative pain management remains a cornerstone in patient's management to ensure a better quality of life. Preemptive analgesia is reported to inhibit the persistence of postoperative pain. AIMS: The aim of this study is to assess the analgesic effectiveness of preincisional infiltration of ketamine following elective abdominal hysterectomy as compared to levobupivacaine. SETTINGS AND DESIGN: This was a prospective, randomized, double-blind study...
July 2017: Saudi Journal of Anaesthesia
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