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Cardiopulmonary exercise testing. (CPET)

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https://www.readbyqxmd.com/read/28935040/cardiopulmonary-exercise-testing-what-is-its-value
#1
REVIEW
Marco Guazzi, Francesco Bandera, Cemal Ozemek, David Systrom, Ross Arena
Compared with traditional exercise tests, cardiopulmonary exercise testing (CPET) provides a thorough assessment of exercise integrative physiology involving the pulmonary, cardiovascular, muscular, and cellular oxidative systems. Due to the prognostic ability of key variables, CPET applications in cardiology have grown impressively to include all forms of exercise intolerance, with a predominant focus on heart failure with reduced or with preserved ejection fraction. As impaired cardiac output and peripheral oxygen diffusion are the main determinants of the abnormal functional response in cardiac patients, invasive CPET has gained new popularity, especially for diagnosing early heart failure with preserved ejection fraction and exercise-induced pulmonary hypertension...
September 26, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28930880/cycling-power-outputs-predict-functional-threshold-power-and-maximum-oxygen-uptake
#2
Joshua Denham, John Scott-Hamilton, Amanda D Hagstrom, Adrian J Gray
Functional threshold power (FTP) has emerged as a correlate of lactate threshold and is commonly assessed by recreational and professional cyclists for tailored exercise programing. To identify whether results from traditional aerobic and anaerobic cycling tests could predict FTP and V˙ O2max, we analysed the association between estimated FTP, maximum oxygen uptake (V˙ O2max [mlkgmin]) and power outputs obtained from a maximal cycle ergometry cardiopulmonary exercise test (CPET) and a 30-s Wingate test in a heterogeneous cohort of cycle-trained and untrained individuals (N=40, mean±SD; age: 32...
September 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28929529/correlation-between-myocardial-deformation-on-three-dimensional-speckle-tracking-echocardiography-and-cardiopulmonary-exercise-testing
#3
Mei Li, Yaran Lu, Cui Fang, Xiaorong Zhang
PURPOSE: Heart failure (HF) is a multifactorial entity that combines derangements in both systolic and diastolic function. The relationship between systolic and diastolic function and exercise capacity is not fully understood. We sought to determine the mechanisms linking cardiac function and exercise tolerance in patients with HF. METHODS: One hundred fifty-six subjects with different cardiac function levels were included in the study. Subjects' 2D echocardiographic, 3D speckle tracking echocardiographic, and cardiopulmonary exercise testing (CPET) data were collected...
September 19, 2017: Echocardiography
https://www.readbyqxmd.com/read/28925073/role-of-cardiopulmonary-exercise-testing-in-clinical-stratification-in-heart-failure-a-position-paper-from-the-committee-on-exercise-physiology-and-training-of-the-heart-failure-association-of-the-european-society-of-cardiology
#4
REVIEW
Ugo Corrà, Pier Giuseppe Agostoni, Stefan D Anker, Andrew J S Coats, Maria G Crespo Leiro, Rudolph A de Boer, Veli-Pekka Hairola, Loreena Hill, Mitja Lainscak, Lars H Lund, Marco Metra, Piotr Ponikowski, Jillian Riley, Petar M Seferović, Massimo F Piepoli
Traditionally, the main indication for cardiopulmonary exercise testing (CPET) in heart failure (HF) was for the selection of candidates to heart transplantation: CPET was mainly performed in middle-aged male patients with HF and reduced left ventricular ejection fraction. Today, CPET is used in broader patients' populations, including women, elderly, patients with co-morbidities, those with preserved ejection fraction, or left ventricular assistance device recipients, i.e. individuals with different responses to incremental exercise and markedly different prognosis...
September 18, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28875971/-exercise-capacity-in-patients-with-pulmonary-sarcoidosis
#5
Justyna Błaut-Jurkowska, Klaudia Knap, Magdalena Kaźnica-Wiatr, Agnieszka Żygadło, Lidia Tomkiewicz-Pająk, Piotr Podolec, Maria Olszowska
Exertional dyspnea is a common manifestation of sarcoidosis. Cardiopulmonary exercise testing (CPET) is a useful tool to evaluate exercise tolerance of sarcoid patients. AIM: The aim of the study was to evaluate of exercise capacity in patients with pulmonary sarcoidosis with regard to duration of the disease. Analysis of differences in physical tolerance between patients with cardiac sarcoidosis and without cardiac sarcoidosis. MATERIALS AND METHODS: 39 patients diagnosed with pulmonary sarcoidosis were enrolled to our study...
August 21, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28874329/outcome-after-turndown-for-elective-abdominal-aortic-aneurysm-surgery
#6
Joshua D Whittaker, Lewis Meecham, Virginia Summerour, Sheirin Khalil, Georgia Layton, Marianne Yousif, Adrian Jennings, Micheal Wall, Jeremy Newman
OBJECTIVES: The aim was to assess the survival of patients who had been turned down for repair of an abdominal aortic aneurysm (AAA) and to examine the factors influencing this. METHODS: This was a retrospective observational study of a prospectively maintained database of all patients turned down for AAA intervention by the Black Country Vascular Network multidisciplinary team (MDT) from January 2013 to December 2015. Data on AAA size, cardiopulmonary exercise testing (CPET) and cause of death were recorded...
September 2, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28857391/estimated-peak-functional-capacity-an-accurate-method-for-assessing-change-in-peak-oxygen-consumption-after-cardiac-rehabilitation
#7
S Nichols, D O Gleadall-Siddall, R Antony, A L Clark, J G F Cleland, S Carroll, L Ingle
OBJECTIVE: Cardiopulmonary exercise testing (CPET) is the 'gold standard' method of determining VO2peak . When CPET is unavailable, VO2peak may be estimated from treadmill or cycle ergometer workloads and expressed as estimated metabolic equivalents (METs). Cardiac rehabilitation (CR) programmes use estimated VO2peak (METs) to report changes in cardiorespiratory fitness (CRF). However, the accuracy of determining changes in VO2peak based on estimated functional capacity is not known. METHODS: A total of 27 patients with coronary heart disease (88·9% male; age 59·5 ± 10·0 years, body mass index 29·6 ± 3·8 kg m(-2) ) performed maximal CPET before and after an exercise-based CR intervention...
August 30, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/28856395/quality-of-life-is-diminished-in-patients-with-tetralogy-of-fallot-with-mild-residual-disease-a-comparison-of-tetralogy-of-fallot-and-isolated-valvar-pulmonary-stenosis
#8
Shivani M Bhatt, Elizabeth Goldmuntz, Amy Cassedy, Bradley S Marino, Laura Mercer-Rosa
The objective of this study is to compare quality of life (QOL) in patients with mild pulmonary insufficiency (PI) after Tetralogy of Fallot (TOF) repair or after balloon dilation for isolated valvar pulmonary stenosis (VPS). A cross-sectional study of patients with TOF (n = 12) and VPS (n = 19), ages 8-18 years, who underwent cardiac magnetic resonance (CMR) and cardiopulmonary exercise test (CPET) was conducted. Patients with genetic syndromes were excluded. The groups were matched by severity and duration of PI using propensity scores...
August 31, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28845719/stress-hormones-at-rest-and-following-exercise-testing-predict-coronary-artery-disease-severity-and-outcome
#9
Dejana Popovic, Svetozar Damjanovic, Tea Djordjevic, Dejana Martic, Svetlana Ignjatovic, Neda Milinkovic, Marko Banovic, Ratko Lasica, Milan Petrovic, Marco Guazzi, Ross Arena
OBJECTIVES: Despite considerable knowledge regarding the importance of stress in coronary artery disease (CAD) pathogenesis, its underestimation persists in routine clinical practice, in part attributable to lack of a standardized, objective assessment. The current study examined the ability of stress hormones to predict CAD severity and prognosis at basal conditions as well as during and following an exertional stimulus. MATERIALS AND METHODS: Forty Caucasian subjects with significant coronary artery lesions (≥50%) were included...
August 28, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28840546/obstructive-sleep-apnea-does-not-impair-cardiorespiratory-responses-to-progressive-exercise-performed-until-exhaustion-in-hypertensive-elderly
#10
Bruno Teixeira Barbosa, Amilton da Cruz Santos, Murillo Frazão, Tulio Rocha Petrucci, Gabriel Grizzo Cucato, Adriana Oliveira Sarmento, Eduardo D S Freitas, Anna Myrna Jaguaribe de Lima, Maria do Socorro Brasileiro-Santos
BACKGROUND: Elderly people have a high prevalence to systemic arterial hypertension (SAH) and obstructive sleep apnea (OSA). Both comorbidities are closely associated and inflict damage on cardiorespiratory capacity. METHODS: In order to assess cardiorespiratory responses to the cardiopulmonary exercise test (CPET) among hypertensive elderly with OSA, we enrolled 28 subjects into two different groups: without OSA (No-OSA: apnea/hypopnea index (AHI) < 5 events/h; n = 15) and with OSA (OSA: AHI ≥ 15 events/h; n = 13)...
August 24, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28798697/cardiac-autonomic-modulation-and-the-kinetics-of-heart-rate-responses-in-the-on-and-off-transient-during-exercise-in-women-with-metabolic-syndrome
#11
Lucas R B E Silva, Antonio R Zamunér, Paulo Gentil, Fagner M Alves, Acácia G F Leal, Viviane Soares, Maria S Silva, Marcus F Vieira, Karina Simões, Gustavo R Pedrino, Ana C S Rebelo
Objective: To test whether women with metabolic syndrome (MS) have impairments in the on- and off-transients during an incremental test and to study whether any of the MS components are independently associated with the observed responses. Research Design and Methods: Thirty-six women aged 35-55 years were divided into a group with MS (MSG, n = 19) and a control group (CG, n = 17). R-R intervals (RRi) and heart rate variability (HRV) were calculated on a beat-to-beat basis and the heart rate (HR) at the on- and off-transient were analyzed during an incremental cardiopulmonary exercise test (CPET)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28791498/patient-reported-dyspnea-correlates-poorly-with-aerobic-exercise-capacity-measured-during-cardiopulmonary-exercise-testing
#12
Dany Gaspard, Jonathan Kass, Stephen Akers, Krystal Hunter, Melvin Pratter
BACKGROUND: Patient-reported dyspnea plays a central role in assessing cardiopulmonary disease. There is little evidence, however, that dyspnea correlates with objective exercise capacity measurements. If the correlation is poor, dyspnea as a proxy for objective assessment may be misleading. OBJECTIVE: To compare patient's perception of dyspnea with maximum oxygen uptake (MaxVO2) during cardiopulmonary exercise testing (CPET). METHODS: Fifty patients undergoing CPET for dyspnea evaluation were studied prospectively...
August 8, 2017: Lung
https://www.readbyqxmd.com/read/28776135/importance-of-non-invasive-right-and-left-ventricular%C3%A2-variables-on-exercise-capacity-in-patients-with-tetralogy-of-fallot-hemodynamics
#13
Christian Meierhofer, Timon Tavakkoli, Andreas Kühn, Kurt Ulm, Alfred Hager, Jan Müller, Stefan Martinoff, Peter Ewert, Heiko Stern
Good quality of life correlates with a good exercise capacity in daily life in patients with tetralogy of Fallot (ToF). Patients after correction of ToF usually develop residual defects such as pulmonary regurgitation or stenosis of variable severity. However, the importance of different hemodynamic parameters and their impact on exercise capacity is unclear. We investigated several hemodynamic parameters measured by cardiovascular magnetic resonance (CMR) and echocardiography and evaluated which parameter has the most pronounced effect on maximal exercise capacity determined by cardiopulmonary exercise testing (CPET)...
August 3, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28765494/effects-of-expiratory-positive-airway-pressure-on-exercise-tolerance-dynamic-hyperinflation-and-dyspnea-in-copd
#14
Ricardo Gass, Pietro Merola, Mariane B Monteiro, Dannuey M Cardoso, Dulciane N Paiva, Paulo Jz Teixeira, Marli M Knorst, Danilo C Berton
INTRODUCTION: The application of expiratory positive airway pressure (EPAP) in patients with COPD during exercise may reduce dynamic hyperinflation, while, on the other hand, it can increase the resistive work of breathing. Therefore, we evaluated the effects of 2 intensities of EPAP during exercise on tolerance, dynamic hyperinflation, and dyspnea in subjects with moderate to very severe COPD. METHODS: We performed a cross-sectional, experimental, 4-visit study...
August 1, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28758084/cardiopulmonary-exercise-test-in-leukemia-patients-after-chemotherapy-a-feasibility-study
#15
Soojae Kim, Ik-Chan Song, Sungju Jee
OBJECTIVE: To explore the feasibility of cardiopulmonary exercise test (CPET) in leukemia patients after chemotherapy. METHODS: Leukemia patients with histologically confirmed hematologic malignancies were reviewed. We evaluated for CPET, between receiving chemotherapy and undergoing stem cell transplantation after 2 weeks. We recorded exercise testing and physiologic parameters during CPET between January 2013 to May 2015. All patients were subjected to symptoms limited to exercise testing, according to the Modified Bruce Protocol...
June 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28737279/exercise-capacity-is-not-decreased-in-children-who-have-undergone-lung-resection-early-in-life-for-congenital-thoracic-malformations-compared-to-healthy-age-matched-children
#16
Ashlee Dunn, Kasey Pearce, Robin Callister, Adam Collison, Matthew Morten, Payal Mandaliya, Lauren Platt, Ben Dascombe, Rajendra Kumar, Hiran Selvadurai, Paul D Robinson, Joerg Mattes
PURPOSE: The purpose of this study was to compare (i) the exercise capacity and (ii) lung function prior to and immediately post cardiopulmonary exercise tests (CPET) of children who underwent early life lung resection for Congenital Pulmonary Airway Malformations (CPAM) to healthy control children. METHOD: Eight children with CPAM (four males, age 9.6 ± 1.8 years) and eight control children without respiratory disease (three males, age 9.4 ± 1.4 years) performed a CPET on a cycle ergometer, during which maximal oxygen consumption (V̇O2max ) and heart rate were measured...
July 24, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28713463/cardiopulmonary-performance-during-maximal-exercise-in-soccer-players-with-alterations-in-renal-function
#17
Anderson Pontes Morales, Felipe Sampaio-Jorge, Luiz Felipe da Cruz Rangel, Jackson de Souza Menezes, Tiago Costa Leite, Beatriz Gonçalves Ribeiro
The aim of this study was to evaluate the curves of cardiorespiratory variables during cardiopulmonary exercise testing (CPET) in soccer players who had acute alterations in the glomerular filtration rate (GFR) after performing the pre-season training protocol. Sixteen male professional soccer players (25 ± 3 years; 179 ± 2 cm; and 77 ± 6 kg) were evaluated for oxygen uptake (VO2), heart rate (HR) and pulse relative oxygen (relative O2 Pulse) curves with intervals corresponding to 10% of the total duration of CPET...
June 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28707733/a-new-equation%C3%A2-to-predict-peak-vo2-in-obese-patients-during-cardiopulmonary-exercise-testing
#18
Alan Carlos Brisola Barbosa, Evandro Fornias Sperandio, Bárbara de Barros Gonze, Giovanna Domingues Spina, Rodolfo Leite Arantes, Antônio Ricardo de Toledo Gagliardi, Marcello Romiti, Victor Zuniga Dourado
We aimed to develop an equation to predict peak VO2 in obese subjects undergoing CPET. In addition, we evaluated and compared three published equations. We randomized 346 obese subjects undergoing CPET into a group for developing the equation (n = 272) and a group for cross-validation (n = 74), compared through the Bland and Altman method. Height, sex and age were responsible for 85·5% of total variability of the peak VO2. Additional 1% and 0·7% of the variability were, respectively, explained by physical inactivity and diabetes...
July 14, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/28705379/prognostic-usefulness-of-cardiopulmonary-exercise-testing-for-managing-patients-with-severe-aortic-stenosis
#19
Van D Le, Gunnar V Jensen, Lars Kjøller-Hansen
The approach to managing asymptomatic or questionably symptomatic patients for aortic stenosis is difficult. We aimed to determine whether cardiopulmonary exercise testing (CPET) is prognostically useful in such patients. Patients judged asymptomatic or questionably symptomatic for aortic stenosis with aortic valve area index <0.6 cm(2)/m(2) and left ventricular ejection fraction ≥0.50 were managed conservatively provided they had either (group 1) normal peak oxygen consumption and peak oxygen pulse (>83% and >95% of the predicted values, respectively) or (group 2) subnormal peak oxygen consumption or peak oxygen pulse but with CPET data pointing to pathologies other than hemodynamic compromise from aortic stenosis...
September 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28689985/oxygen-consumption-and-carbon-dioxide-recovery-kinetics-in-the-prediction-of-coronary-artery-disease-severity-and-outcome
#20
Dejana Popovic, Dejana Martic, Tea Djordjevic, Vesna Pesic, Marco Guazzi, Jonathan Myers, Reza Mohebi, Ross Arena
BACKGROUND: Revascularization appears to be beneficial only in patients with high levels of ischemia. This study examined the utility of gas analysis during the recovery phase of cardiopulmonary exercise testing (CPET) in predicting coronary artery disease (CAD) severity and prognosis. METHODS: 40 Caucasian patients (21.2% females), mean age 63.5±7.6 with significant coronary artery lesions (≥50%) were studied. Within two months of coronary angiography, CPET on a treadmill (TM) and recumbent ergometer (RE) were performed on two visits 2-4days apart; subjects were subsequently followed 32±10months...
December 1, 2017: International Journal of Cardiology
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