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Cardiopulmonary exercise testing. (CPET)

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https://www.readbyqxmd.com/read/28511070/impact-of-exaggerated-blood-pressure-response-in-normotensive-individuals-on-future-hypertension-and-prognosis-systematic-review-according-to-prisma-guideline
#1
REVIEW
Karsten Keller, Kathrin Stelzer, Mir Abolfazl Ostad, Felix Post
PURPOSE: Arterial hypertension (aHT) is the leading risk factor for morbidity and mortality worldwide. Blood pressure (BP) deviation at rest is well defined and accompanies risk for cardiovascular events and cardiovascular mortality. A growing body of evidence emphasises that an exaggerated blood pressure response (EBPR) in cardiopulmonary exercise testing (CPET) could help to identify seemingly cardiovascular healthy and normotensive subjects, who have an increased risk of developing aHT and cardiovascular events in the future...
May 13, 2017: Advances in Medical Sciences
https://www.readbyqxmd.com/read/28510737/total-haemoglobin-mass-but-not-haemoglobin-concentration-is-associated-with-preoperative-cardiopulmonary-exercise-testing-derived-oxygen-consumption-variables
#2
J M Otto, J O M Plumb, D Wakeham, E Clissold, L Loughney, W Schmidt, H E Montgomery, M P W Grocott, T Richards
Background: Cardiopulmonary exercise testing (CPET) measures peak exertional oxygen consumption ( V˙O2peak ) and that at the anaerobic threshold ( V˙O2 at AT, i.e. the point at which anaerobic metabolism contributes substantially to overall metabolism). Lower values are associated with excess postoperative morbidity and mortality. A reduced haemoglobin concentration ([Hb]) results from a reduction in total haemoglobin mass (tHb-mass) or an increase in plasma volume. Thus, tHb-mass might be a more useful measure of oxygen-carrying capacity and might correlate better with CPET-derived fitness measures in preoperative patients than does circulating [Hb]...
May 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28508270/the-impact-of-combined-cardiopulmonary-exercise-testing-and-spect-myocardial-perfusion-imaging-on-downstream-evaluation-and-management
#3
Georgios Christopoulos, John Bois, Thomas G Allison, Martin Rodriguez-Porcel, Panithaya Chareonthaitawee
OBJECTIVE: The diagnostic yield of combined cardiopulmonary exercise testing (CPET) and myocardial perfusion imaging (MPI) in patients referred for stress testing has received limited study. METHODS: We evaluated consecutive patients who underwent combined CPET-MPI at a single tertiary referral center between 2011 and 2015. An abnormal CPET was defined as any of the following: reduced oxygen consumption, cardiac output impairment, or pulmonary impairment. Normal MPI was defined as the absence of resting or stress perfusion defect...
May 15, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28502420/cardiopulmonary-exercise-testing-and-second-line-pulmonary-function-tests-to-detect-obstructive-pattern-in-symptomatic-smokers-with-borderline-spirometry
#4
Fabiano Di Marco, Silvia Terraneo, Sara Job, Rocco Francesco Rinaldo, Giuseppe Francesco Sferrazza Papa, Maria Adelaide Roggi, Pierachille Santus, Stefano Centanni
BACKGROUND: The need for additional research on symptomatic smokers with normal spirometry has been recently emphasized. Albeit not meeting criteria for Chronic obstructive pulmonary disease (COPD) diagnosis, symptomatic smokers may experience activity limitation, evidence of airway disease, and exacerbations. We, therefore, evaluated whether symptomatic smokers with borderline spirometry (post-bronchodilator FEV1/FVC ratio between 5th to 20th percentile of predicted values) have pulmonary function abnormalities at rest and ventilatory constraints during exercise...
June 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28489684/calculated-versus-measured-mvv-surrogate-marker-of-ventilatory-capacity-in-pediatric-cpet
#5
Kelly L Colwell, Rajeev Bhatia
INTRODUCTION: Maximum Voluntary Ventilation (MVV), a surrogate marker of maximum ventilatory capacity, allows for measuring ventilatory reserve during Cardiopulmonary Exercise Stress Testing (CPET) which is necessary to assess ventilatory limitation. MVV can be measured directly during a patient maneuver or indirectly by calculating from FEV1 (FEV1 X 40). We investigated for a potential difference between calculated MVV and measured MVV in pediatric subjects, and which better represents maximum ventilatory capacity during CPET...
May 9, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28477381/effect-of-diltiazem-on-exercise-capacity-after-heart-transplantation
#6
Sara Varnado, Yael Peled-Potashnik, Ashley Huntsberry, Brian D Lowes, Ronald Zolty, Adam Burdorf, Elizabeth R Lyden, Michael J Moulton, John Y Um, Eugenia Raichlin
BACKGROUND: Sinus tachycardia (ST) is common after heart transplantation (HTx). The aim of the study was to evaluate the effect of Diltiazem treatment during the first year after HTx on heart rate (HR), cardiac allograft function and exercise capacity. METHODS: From the total cohort, 25 HTx recipients started Diltiazem treatment 4±2 weeks after HTx and continued it for at least 1 year (Diltiazem group). Each study case was matched to a control. All patients underwent hemodynamic assessment and cardiopulmonary exercise test (CPET) at one year after HTx...
May 6, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/28471812/comparisons-of-noninvasive-methods-used-to-assess-exercise-stroke-volume-in-hfpef
#7
Erik H Van Iterson, Thomas P Olson, Barry A Borlaug, Bruce D Johnson, Eric M Snyder
INTRODUCTION: Cardiopulmonary exercise testing (CPET) plays an important role in properly phenotyping signs and symptoms of heart failure with preserved ejection fraction (HFpEF). The prognostic value of CPET is strengthened when accompanied by cardiac hemodynamic measurements. Although recognized as the 'Gold' standard, cardiac catheterization is impractical for routine CPET. Thus, advancing the scientific/methodologic understanding of noninvasive techniques for exercise cardiac hemodynamic assessment is clinically impactful in HFpEF...
May 4, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28467885/diving-and-pulmonary-physiology-surfactant-binding-protein-lung-fluid-and-cardiopulmonary-test-changes-in-professional-divers
#8
Zora Susilovic-Grabovac, Cristina Banfi, Denise Brusoni, Massimo Mapelli, Stefania Ghilardi, Ante Obad, Darija Bakovic-Kramaric, Zeljko Dujic, Piergiuseppe Agostoni
Alteration of breathing pattern ranging from an increase of respiratory rate to overt hyperventilation during and after SCUBA diving is frequently reported and is associated with intrathoracic fluid overload. This study was undertaken to assess breathing efficiency after diving and the association with damage of alveolar cells. Ventilation efficiency (VE/VCO2) during maximal cardiopulmonary exercise test (CPET) before and 2h after a standard protocol dive has been analyzed in twelve professional males divers (39...
April 30, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28450916/exercise-training-on-chronotropic-response-and-exercise-capacity-in-patients-with-type-2-diabetes-mellitus
#9
Li Jin, Gao Min, Chen Wei, He Min, Zhou Jie
The study was designed to observe the effects and relationship of exercise on chronotropic response (CR) and exercise capacity in patients with type 2 diabetes mellitus (T2DM). A total of 30 patients with T2DM underwent symptom-limited cardiopulmonary exercise testing (CPET) after excluding contraindication. For each subject individualized exercise prescription was formulated, and they received 12 weeks of exercise training after CPET retest to complete the comparison of CR indicators, including the ratio of maximum exercise heart rate to predicted maximum heart rate value (rHR), heart rate reserve rate (HRRes), heart rate recovery (HRR) of 1-6 min after exercise termination (HRR1-6), exercise capacity (peak VO2/kg) and other indicators...
March 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28427551/cardiopulmonary-exercise-factors-predict-survival-in-patients-with-advanced-interstitial-lung-disease-referred-for-lung-transplantation
#10
Aimee M Layton, Hilary F Armstrong, Hanyoung P Kim, Kimbery S Meza, Frank D'Ovidio, Selim M Arcasoy
BACKGROUND: The purpose of this work was to determine if parameters assessed during Cardiopulmonary Exercise Testing (CPET) while using supplemental oxygen can independently predict one-year transplant-free survival in patients with Interstitial Lung Disease (ILD) referred for lung transplant evaluation. METHODS: We performed a chart review of patients with ILD who completed CPET with 30% FiO2 and gathered spirometry, pulmonary hemodynamic, six-minute walk, and CPET data...
May 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28419206/short-term-preoperative-exercise-therapy-does-not-improve-long-term-outcome-after-lung-cancer-surgery-a-randomized-controlled-study%C3%A2
#11
Wolfram Karenovics, Marc Licker, Christoph Ellenberger, Michel Christodoulou, John Diaper, Chetna Bhatia, John Robert, Pierre-Olivier Bridevaux, Frédéric Triponez
OBJECTIVES: Poor aerobic fitness is a potential modifiable risk factor for long-term survival and quality of life in patients with lung cancer. This randomized trial evaluates the impact of adding rehabilitation (Rehab) with high-intensity interval training (HIIT) before lung cancer surgery to enhance cardiorespiratory fitness and improve long-term postoperative outcome. METHODS: Patients with operable lung cancer were randomly assigned to usual care (UC, n  = 77) or to intervention group (Rehab, n  = 74) that entailed HIIT that was implemented only preoperatively...
April 17, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28417202/cardiorespiratory-fitness-and-muscle-strength-in-pancreatic-cancer-patients
#12
Dorothea Clauss, Christine Tjaden, Thilo Hackert, Lutz Schneider, Cornelia M Ulrich, Joachim Wiskemann, Karen Steindorf
PURPOSE: Cancer patients frequently experience reduced physical fitness due to the disease itself as well as treatment-related side effects. However, studies on physical fitness in pancreatic cancer patients are missing. Therefore, we assessed cardiorespiratory fitness and muscle strength of pancreatic cancer patients. METHODS: We included 65 pancreatic cancer patients, mostly after surgical resection. Cardiorespiratory fitness was assessed using cardiopulmonary exercise testing (CPET) and 6-min walk test (6MWT)...
April 17, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28388274/six-minute-stepper-test-to-set-pulmonary-rehabilitation-intensity-in-patients-with-copd-a-retrospective-study
#13
Tristan Bonnevie, Francis-Edouard Gravier, Marie Leboullenger, Clément Médrinal, Catherine Viacroze, Antoine Cuvelier, Jean-François Muir, Catherine Tardif, David Debeaumont
Pulmonary rehabilitation (PR) improves outcomes in patients with chronic obstructive pulmonary disease (COPD). Optimal assessment includes cardiopulmonary exercise testing (CPET), but consultations are limited. Field tests could be used to individualize PR instead of CPET. The six-minute stepper test (6MST) is easy to set up and its sensitivity and reproducibility have previously been reported in patients with COPD. The aim of this study was to develop a prediction equation to set intensity in patients attending PR, based on the 6MST...
April 7, 2017: COPD
https://www.readbyqxmd.com/read/28386795/-metabolic-and-cardiovascular-response-to-exercise-in-patients-with-type-1-diabetes
#14
I Turinese, P Marinelli, M Bonini, M Rossetti, G Statuto, T Filardi, A Paris, A Lenzi, S Morano, P Palange
PURPOSE: Physical activity is an effective therapeutic tool for cardiovascular risk prevention. However, exercise aerobic capacity of patients with type 1 diabetes (T1DM) has not been thoroughly investigated. Aim of the present study is to evaluate exercise aerobic capacity in patients with T1DM compared to a normal control population. METHODS: This observational study included 17 T1DM patients and 17 matched healthy volunteers. Cardiopulmonary exercise test (CPET) was conducted on an electronically-braked cycle ergometer...
April 6, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28382813/oxygen-uptake-and-body-composition-after-aquatic-physical-training-in-women-with-fibromyalgia-a-randomized-controlled-trial
#15
Carolina P Andrade, Antonio R Zamunér, Meire Forti, Thalita F França, Nayara Y Tamburús, Ester Silva
BACKGROUND: Aquatic physical training (APT) has been strongly recommended to improve symptoms in fibromyalgia syndrome (FMS). However, its effects on body composition and whether lean body mass (LBM) directly influences the aerobic functional capacity of this population are still not clear. AIM: To investigate whether APT can help improve body composition and increase the aerobic functional capacity in women with FMS, and whether oxygen consumption (VO2) related to LBM can better quantify the functional capacity of this population...
April 4, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28382081/changes-in-strain-pattern-and-exercise-capacity-after-transcatheter-closure-of-atrial-septal-defects
#16
Jung Yoon Kim, Bong-Sic Yun, Sunho Lee, Se Yong Jung, Jae Young Choi, Nam Kyun Kim
BACKGROUND AND OBJECTIVES: Assessment of left ventricle (LV) function by using strain and strain rate is popular in the clinical setting. However, the use of these echocardiographic tools in assessing right ventricle (RV) failure, and the manner in which they both reflect the functional capacity of the patient, remains poorly understood. This study aimed to investigate the change in exercise capacity and strain between before and (1 month) after the transcatheter closure of atrial septal defects (ASDs)...
March 2017: Korean Circulation Journal
https://www.readbyqxmd.com/read/28336390/is-parasternal-intercostal-emg-an-accurate-surrogate-of-respiratory-neural-drive-and-biomarker-of-dyspnea-during-cycle-exercise-testing
#17
Andrew H Ramsook, Reid A Mitchell, Tyson Bell, Suzanne Calli, Chris Kennedy, Jenny Lehmann, Matt Thompson, Joseph H Puyat, Jordan A Guenette
Recent evidence suggests that surface electromyography of the parasternal intercostals (EMGpara) can be a non-invasive alternative to diaphragmatic EMG (EMGdi) for estimating neural respiratory drive (NRD) during cardiopulmonary exercise testing (CPET). The purpose of this study was to determine if non-respiratory muscles influence EMGpara by having subjects place their hands on (Hon) and off (Hoff) the handlebars during cycling-based CPET. Ten healthy adults performed an incremental cycling test until volitional exhaustion...
March 20, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28322759/validation-and-refinement-of-prediction-models-to-estimate-exercise-capacity-in-cancer-survivors-using-the-steep-ramp-test
#18
Martijn M Stuiver, Caroline S Kampshoff, Saskia Persoon, Wim Groen, Willem van Mechelen, Mai J M Chinapaw, Johannes Brug, Frans Nollet, Marie-José Kersten, Goof Schep, Laurien M Buffart
OBJECTIVE: To further test the validity and clinical usefulness of the steep ramp test (SRT) in estimating exercise tolerance in cancer survivors by external validation and extension of previously published prediction models for peak oxygen consumption (Vo2peak) and peak power output (Wpeak). DESIGN: Cross-sectional study. SETTING: Multicenter. PARTICIPANTS: Cancer survivors (N=283) in 2 randomized controlled exercise trials...
March 18, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28320577/pre-operative-functional-cardiovascular-reserve-is-associated-with-acute-kidney-injury-after-intervention
#19
A Saratzis, J Shakespeare, O Jones, M J Bown, A Mahmood, C H E Imray
BACKGROUND: Acute kidney injury (AKI) is a common complication after endovascular intervention, associated with poor short and long-term outcomes. However, the mechanisms underlying AKI development remain poorly understood. The impact of pre-existing cardiovascular disease and low cardiovascular reserve (CVR) in AKI is unclear; it remains unknown whether AKI is primarily related to pre-existing comorbidity or to procedural parameters. The association between CVR and AKI after EVAR was therefore assessed...
March 17, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28318852/cardiorespiratory-optimal-point-during-exercise-testing-as-a-predictor-of-all-cause-mortality
#20
Plínio S Ramos, Claudio Gil S Araújo
INTRODUCTION AND AIM: The cardiorespiratory optimal point (COP) is a novel index, calculated as the minimum oxygen ventilatory equivalent (VE/VO2) obtained during cardiopulmonary exercise testing (CPET). In this study we demonstrate the prognostic value of COP both independently and in combination with maximum oxygen consumption (VO2max) in community-dwelling adults. METHODS: Maximal cycle ergometer CPET was performed in 3331 adults (66% men) aged 40-85 years, healthy (18%) or with chronic disease (81%)...
April 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
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