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https://www.readbyqxmd.com/read/28079746/sentinel-surveillance-for-expedited-partner-therapy-prescriptions-using-pharmacy-data-in-2-new-york-city-neighborhoods-2015
#1
Ebiere Okah, Vibhuti Arya, Meighan Rogers, Michelle Kim, Julia Ann Schillinger
BACKGROUND: Expedited partner therapy (EPT) for Chlamydia trachomatis (Ct) is the practice of providing Ct-infected patients with medication, or prescription (prescription-EPT) to deliver to their sex partners without first examining those partners. New York City (NYC) providers commonly use prescription-EPT, yet NYC pharmacists report only occasional receipt of EPT prescriptions. This project assessed the frequency of EPT prescriptions filled in 2 NYC neighborhoods. METHODS: The 2 NYC facilities reporting the most frequent use of prescription-EPT were identified from Ct provider case reports and contacted to ascertain their EPT practices...
February 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28011635/hemoglobin-kirklareli-%C3%AE-h58l-a-new-variant-associated-with-fe-deficiency-and-increased-co-binding
#2
Emmanuel Bissé, Christine Schaeffer-Reiss, Alain Van Dorsselaer, Tchilabalo Dilezitoko Alayi, Thomas Epting, Karl Winkler, Andres S Benitez Cardenas, Jayashree Soman, Ivan Birukou, Premila P Samuel, John S Olson
Mutations in hemoglobin can cause a wide range of phenotypic outcomes, including anemia due to protein instability and red cell lysis. Uncovering the biochemical basis for these phenotypes can provide new insights into hemoglobin structure and function as well as identify new therapeutic opportunities. We report here a new hemoglobin α chain variant in a female patient with mild anemia, whose father also carries the trait and is from the Turkish city of Kirklareli. Both the patient and her father had a His58(E7)→Leu mutation in α1...
December 23, 2016: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28005010/simultaneous-quantitative-imaging-of-electrical-properties-and-proton-density-from-b1-maps-using-mri
#3
Jiaen Liu, Pierre-Francois Van de Moortele, Xiaotong Zhang, Yicun Wang, Bin He
Electrical conductivity and permittivity of biological tissues are important diagnostic parameters and are useful for calculating subject-specific specific absorption rate distribution. On the other hand, water proton density also has clinical relevance for diagnosis purposes. These two kinds of tissue properties are inevitably associated in the technique of electrical properties tomography (EPT), which can be used to map in vivo electrical properties based on the measured B1 field distribution at Larmor frequency using magnetic resonance imaging (MRI)...
September 2016: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/27993262/-the-recognition-of-emotions-empathy-and-moral-judgment-in-the-national-mental-health-survey-in-colombia-2015
#4
Diana Matallana, Carlos Gómez-Restrepo, Paulina Ramirez, Nathalie Tamayo Martínez, Martin Rondon
BACKGROUND: Social cognition refers to the mental processes involved in social interactions. Different aspects, such as the perception of others, self-knowledge, motivation and the cultural context, can modulate empathy responses and moral judgments regarding the actions of others. The National Mental Health Survey (ENSM for its acronym in Spanish) explored aspects of social cognition such as the perception of emotions, empathy and moral judgment in situations in which another person experiences pain...
December 2016: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/27975201/health-assessment-using-aqua-quality-indicators-of-alpine-streams-khunjerab-national-park-gilgit-pakistan
#5
Salar Ali, Junfeng Gao, Farida Begum, Atta Rasool, Muhammad Ismail, Yongjiu Cai, Shaukat Ali, Shujaat Ali
This preliminary research was conducted to evaluate the alpine stream health by using water quality as an indicator in Khunjerab National park of the Karakoram ranges located in Pak-China boarder Pakistan having altitude of 3660 m. This study investigated the stream health in the context of the presence or absence of sensitive species, their diversity, and their taxa richness. The water and macroinvertebrate samples were collected from 17 different locations from upstream and downstream of the river by using random sampling method...
December 14, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27966832/design-of-block-copolymer-micellar-aggregates-for-co-delivery-of-enzyme-and-anticancer-prodrug
#6
Hongping Li, Lulu Chen, Yuting Shi, Binbin Yuan, Yingxia Ma, Hua Wei, Guanghui Zhao
Traditional enzyme-prodrug therapy (EPT) is a two-step strategy, which has many serious deficiencies, so having a one-step EPT treatment becomes a problem of immediate interest. This study aims to achieve an effective co-delivery of horseradish peroxidase (HRP) as a kind of enzyme for prodrug activation and ethyl 3-indoleacetate (EIA) as anticancer prodrug. A ternary block copolymer PEG-PAsp(AED)-CA consisting of poly(ethylene glycol) (PEG), reduction-sensitive poly (N-(2,2'-dithiobis(ethylamine)) aspartamide) PAsp(AED), and cholic acid (CA) was synthesized and assembled into spherical micelles which encapsulated EIA in its hydrophobic core and HRP in a reduction-sensitive interlayer...
December 14, 2016: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/27935901/sodium-supply-influences-plasma-sodium-concentration-and-the-risks-of-hyper-and-hyponatremia-in-extremely-preterm-infants
#7
Cornelia Späth, Elisabeth Stoltz Sjöström, Fredrik Ahlsson, Johan Ågren, Magnus Domellöf
BackgroundHyper- and hyponatremia occur frequently in extremely preterm (EPT) infants. Our purpose was to investigate plasma sodium (P-Na) concentrations, the incidence of hyper- and hyponatremia, and the impact of possible predisposing factors in EPT infants.MethodsIn this observational study, we analysed data from the EXtremely PREterm (< 27wks.) infants in Sweden Study (EXPRESS, n=707). Detailed nutritional, laboratory and weight data were collected retrospectively from patient records.ResultsMean ± SD P-Na increased from 135...
December 9, 2016: Pediatric Research
https://www.readbyqxmd.com/read/27933616/efficacy-of-preoperative-ibuprofen-and-meloxicam-on-the-success-rate-of-inferior-alveolar-nerve-block-for-teeth-with-irreversible-pulpitis
#8
Yazdan Shantiaee, Sahar Javaheri, Amir Movahhedian, Sarah Eslami, Omid Dianat
OBJECTIVE: The purpose of this study was to determine whether premedication with ibuprofen or meloxicam increases the success rate of anaesthesia in teeth with irreversible pulpitis. MATERIALS AND METHODS: In this parallel, double-blind clinical trial, 92 patients diagnosed with irreversible pulpitis were randomly divided into four groups of 23 patients. The first group (the no-premedication group) received no premedication, the second group (the meloxicam group) received 7...
December 8, 2016: International Dental Journal
https://www.readbyqxmd.com/read/27924920/online-flow-cytometry-reveals-microbial-dynamics-influenced-by-concurrent-natural-and-operational-events-in-groundwater-used-for-drinking-water-treatment
#9
Michael D Besmer, Jannis Epting, Rebecca M Page, Jürg A Sigrist, Peter Huggenberger, Frederik Hammes
Detailed measurements of physical, chemical and biological dynamics in groundwater are key to understanding the important processes in place and their influence on water quality - particularly when used for drinking water. Measuring temporal bacterial dynamics at high frequency is challenging due to the limitations in automation of sampling and detection of the conventional, cultivation-based microbial methods. In this study, fully automated online flow cytometry was applied in a groundwater system for the first time in order to monitor microbial dynamics in a groundwater extraction well...
December 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27916374/transfer-and-priming-of-surgical-skills-across-minimally-invasive-surgical-platforms
#10
Ahmed Zihni, Tianjia Ge, Shuddhadeb Ray, Robert Wang, Zhe Liang, Jaime A Cavallo, Michael M Awad
BACKGROUND: Robot-assisted laparoscopic surgery (RALS) uses 3-dimensional visualization and wristed instruments that provide more degrees of freedom than rigid traditional laparoscopic (TLS) instrumentation. These features have been touted to improve accuracy and efficiency during surgical task performance. Little is known, however, about the transferability of skills between the two platforms or whether task performance on one platform primes surgeons for task performance on the other...
November 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27914224/a-systematic-review-of-epileptic-seizures-in-adults-with-subdural-haematomas
#11
REVIEW
Sae-Yeon Won, Juergen Konczalla, Daniel Dubinski, Adriano Cattani, Colleen Cuca, Volker Seifert, Felix Rosenow, Adam Strzelczyk, Thomas M Freiman
BACKGROUND: Posttraumatic epileptic seizures (PTS) are a serious complication in patients with subdural haematoma (SDH). However, to date, several studies have shown discordances about SDH-associated seizures in terms of incidence, risk factors and prophylactic antiepileptic treatment. OBJECTIVE: The aim of this study was to analyse the incidence, risk factors of PTS and the role of prophylactic antiepileptic treatment in patients with SDH. DATA SOURCES: A systematic literature review examining PTS in patients with SDH was performed using PubMed gateway, Cochrane Central Register of Controlled Trials, and Excerpta Medica dataBASE between September 1961 and February 2016...
November 25, 2016: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/27909953/the-pe%C3%A3-alosa-principle-of-transportation-democracy-lessons-from-bogot%C3%A3-on-the-morality-of-urban-mobility
#12
Shane Epting
The mayor of Bogotá, Enrique Peñalosa strives to deliver transit services that promote social equity through bicycle lanes, improved sidewalks, and a world-famous Bus Rapid Transit (BRT) system, "TransMilenio." Through examining the principles that guide his planning, we can flesh out a starting point for socially just transit systems. While such measures can alleviate several harms that transit systems cause, they rest on an incomplete foundation due to their top-down nature. To amend this situation, the author argues for a restorative justice approach to transportation democracy, using examples from Peñalosa's mayoral tenure...
December 1, 2016: Science and Engineering Ethics
https://www.readbyqxmd.com/read/27893596/pharmacists-knowledge-and-practices-surrounding-expedited-partner-therapy-for-chlamydia-trachomatis-new-york-city-2012-and-2014
#13
Amanda Reid, Meighan E Rogers, Vibhuti Arya, Zoe R Edelstein, Julia A Schillinger
BACKGROUND: Health care providers in New York City can prescribe treatment for Chlamydia trachomatis (Ct) for a patient's partner without the partner having a medical evaluation ("prescription-expedited partner therapy" [EPT]), and use of prescription-EPT is common. However, there is little known about pharmacists' knowledge and practices surrounding EPT. METHODS: Two cross-sectional surveys, in 2012 and 2014, were conducted with representative samples of supervising pharmacists in NYC neighborhoods with high rates of Ct infection...
November 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27893595/the-impact-of-prescriptions-on-sex-partner-treatment-using-expedited-partner-therapy-for-chlamydia-trachomatis-infection-new-york-city-2014-2015
#14
Ashley Oliver, Meighan Rogers, Julia A Schillinger
BACKGROUND: Chlamydia trachomatis reinfections, often resulting from resuming sex with untreated partners, can increase the risk of pelvic inflammatory disease, infertility, and ectopic pregnancy. Expedited partner therapy (EPT) has been shown to prevent reinfection when provided as medication (Medication-EPT) that patients give to sex partners; however, EPT is often provided as a prescription (Prescription-EPT). We compared partner treatment outcomes for Medication-EPT versus Prescription-EPT...
November 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27876040/botulinum-toxin-treatment-for-essential-palatal-tremors-presenting-with-nasal-clicks-instead-of-pulsatile-tinnitus-a-case-report
#15
Yufeng Ye, Shiyu Liao, Baozhen Luo, Liyan Ni
BACKGROUND: In this study, we report a rare case of an adult patient with essential palatal tremors (EPT) presenting as nasal clicks, instead of otic clicks or objective pulsatile tinnitus in common EPT. CASE PRESENTATION: Nasal endoscopic examination and EMG recordings of the soft palate muscles were performed to confirm the source of the clicks. Initial treatment with lidocaine provided symptomatic relief for four hours. The patient was then treated with four simultaneous injections of 12...
November 22, 2016: Head & Face Medicine
https://www.readbyqxmd.com/read/27870827/augmented-th17-type-immune-responses-in-preterm-neonates-exposed-to-histologic-chorioamnionitis
#16
Daniel C Rito, Luke T Viehl, Paula M Buchanan, Seema Haridas, Joyce M Koenig
BACKGROUND: Histologic chorioamnionitis (HCA) is a placental inflammatory disorder that frequently precedes preterm delivery. HCA increases risk for long-standing inflammatory injury and may influence immune programming, particularly in preterm (PT) neonates. We hypothesized that HCA exposure is associated with an increased circulating frequency of pro-inflammatory, Th17-type responses. METHODS: Placental cord blood was collected from HCA-exposed or control neonates (23-41 weeks gestation)...
November 21, 2016: Pediatric Research
https://www.readbyqxmd.com/read/27866087/a-predictive-model-for-estimating-regional-skeletal-muscle-size-by-two-point-dixon-magnetic-resonance-imaging-in-healthy-koreans
#17
Cheol-Min Kim, Chang-Hyung Lee, Young A Choi, Byoung-Chul Kim, Duk-Young Jung, Myung-Jun Shin
This study was undertaken to develop and cross-validate reference and individual predictive models for estimating functional thigh muscle cross-sectional area (TCSA) by 2-point Dixon magnetic resonance imaging (MRI). TCSAs of dominant sides at the mid-thigh level were measured by 2-point Dixon MRI ((MRI)TCSA). Functional (MRI)TCSA were compared with the predictive models in a sample of 92 younger (20-40 years; 28.55±4.87; n=50) and older (>65years; 71.22±4.82; n=42) Koreans. Lean body masses were measured by dual energy X-ray absorptiometry ((DXA)LBM), and thigh isokinetic muscle strengths, extension peak torque at 60°/sec, were measured using a Biodex(®) dynamometer ((Biodex)EPT)...
March 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27849774/130-glucocorticoid-receptor-profiles-in-children-undergoing-cardiopulmonary-bypass
#18
Vishal Gunnala, Nga Du, Emily Petersen, Hannah Palac, John Costello, Carl Backer, Conrad Epting, Eric Wald
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27846248/elective-tracheotomy-practices-in-turkey
#19
Bulent Gucyetmez, Hakan Korkut Atalan, Nahit Cakar
OBJECTIVES: Elective tracheotomy (ET) procedures in intensive care units (ICU) might be different in accordance with countries and ICUs' features. The aim of the present study was to search the epidemiology of ET procedures in Turkey. METHODS: A questionnaire which consists of 43 questions was sent by e-mail to 238 ICUs which were officially recognized by The Turkish Ministry of Health. All answers were obtained between August 1, 2015 and August 31, 2015. RESULTS: Two hundred and three ICUs (85...
2016: PloS One
https://www.readbyqxmd.com/read/27818602/effects-of-extreme-prematurity-on-numerical-skills-and-executive-function-in-kindergarten-children-an-application-of-partially-ordered-classification-modeling
#20
Curtis Tatsuoka, Bridget McGowan, Tomoko Yamada, Kimberly Andrews Espy, Nori Minich, H Gerry Taylor
Although mathematics disabilities (MD) are common in extremely preterm/extremely low birth weight (EPT/ELBW) children, little is known about the nature of these problems. In this study partially ordered set (POSET) models were applied to classify 140 EPT/ELBW kindergarten children (gestational age <28 weeks and/or birth weight <1000 g) and 110 normal birth weight (NBW) controls into profiles of numerical and cognitive skills. Models based on five numerical skills and five executive function and processing speed skills provided a good fit to performance data...
July 2016: Learning and Individual Differences
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