keyword
https://read.qxmd.com/read/36513509/fecal-microbiota-transplantation-new-possibility-to-influence-the-results-of-therapy-of-cancer-patients
#1
JOURNAL ARTICLE
L Křížová, I Benešová, J Špaček, L Petruželka, M Vočka
BACKGROUND: The intestinal microbio-me is essential for the function of the human body, it affects not only metabolism and digestion, but also the immune and neurobehavioral systems. The composition of the human intestinal microbio-me has been of interest to many scientific teams around the world in recent years, aided by the rapid development of molecular genetics methods. Intestinal microbio-me imbalance (so-called dysbio-sis) can help develop several pathological conditions such as autoimmune diseases or can be involved in the process of carcinogenesis...
2022: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
https://read.qxmd.com/read/36504212/-anti-inflammatory-therapies-for-cardiovascular-diseases-novel-evidence-clinical-implications-and-future-perspectives
#2
REVIEW
Felice Gragnano, Paolo Calabrò, Vincenzo De Sio, Massimo Imazio, Giuseppe Patti, Raffaele De Caterina, Pasquale Perrone Filardi, Sergio Leonardi
Inflammation plays an important role in cardiovascular disease. Growing evidence suggests a profound involvement of the inflammatory response in the development and progression of atherosclerosis and its complications. In patients with atherosclerotic cardiovascular disease (ASCVD), residual cardiovascular risk often remains high despite optimal medical therapy and the achievement of the therapeutic targets recommended by current guidelines. Among the multiple components of residual risk, residual inflammatory risk, assessed by plasma levels of high-sensitivity C-reactive protein, has shown a strong association with the incidence of cardiovascular events...
December 2022: Giornale Italiano di Cardiologia
https://read.qxmd.com/read/36220420/acute-kidney-injury-due-to-antimicrobial-therapy
#3
JOURNAL ARTICLE
Viktor Klementa, Naděžda Petejová, Josef Zadražil, Pavel Horák, Jitka Prošková, Olga Klementová
One of the common causes of acute kidney injury (AKI) is drug nephrotoxicity. A large group of drugs associated with AKI includes a considerable number of antimicrobials. Clinical manifestations range from mild forms of tubular damage to significant deterioration of renal function requiring renal replacement therapy. Several mechanisms have been described, although the most common are acute interstitial nephritis, acute tubular necrosis, crystalic nephropathy or proximal/distal tubulopathy with electrolyte abnormalities...
2022: Vnitr̆ní Lékar̆ství
https://read.qxmd.com/read/34669308/-il-paziente-con-insufficienza-renale-cronica-terapie-tipiche-modalit%C3%A3-di-somministrazione-farmacocinetica-e-farmacodinamica
#4
JOURNAL ARTICLE
Alessandra Marega
No abstract text is available yet for this article.
September 7, 2021: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://read.qxmd.com/read/32757171/position-paper-on-the-safety-efficacy-profile-of-direct-oral-anticoagulants-in-patients-with-chronic-kidney-disease-consensus-document-of-societ%C3%A3-italiana-di-nefrologia-sin-federazione-centri-per-la-diagnosi-della-trombosi-e-la-sorveglianza-delle-terapie-antitrombotiche
#5
JOURNAL ARTICLE
Elvira Grandone, Filippo Aucella, Doris Barcellona, Giuliano Brunori, Giacomo Forneris, Paolo Gresele, Marco Marietta, Daniela Poli, Sophie Testa, Armando Tripodi, Simonetta Genovesi
Direct oral anticoagulants (DOAC) are mostly prescribed to prevent cardioembolic stroke in patients with non-valvular atrial fibrillation (AF). An increasing number of guidelines recommend DOAC in AF patients with preserved renal function for the prevention of thromboembolism and an increased use of DOAC in daily practice is recorded also in elderly patients. Aging is associated with a reduction of glomerular filtration rate and impaired renal function, regardless of the cause, increases the risk of bleeding...
February 2021: Journal of Nephrology
https://read.qxmd.com/read/24456785/systematic-review-and-meta-analysis-of-target-terapies-for-the-treatment-of-metastatic-renal-cancer
#6
REVIEW
Marcela Durán, Wagner Matheus, Ubirajara Ferreira, Otávio Clark
OBJECTIVES: At present there are several drugs for the treatment of advanced renal cell carcinoma (ARCC). The main objective of this work was to perform a systematic review (SR) and meta-analysis (MA) of clinical randomized studies that compared target cell therapies (TCT). MATERIALS AND METHODS: SR identified clinical randomized trials that compared TCT versus interferon-alpha in the treatment of patients with ARCC. In order to analyze efficiency, it was evaluated free-survival progression (FSP), total survival (TS) and response rate (RR)...
November 2013: International Braz J Urol: Official Journal of the Brazilian Society of Urology
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