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https://www.readbyqxmd.com/read/29457051/signet-ring-cell-carcinoma-ileal-crohn-disease-or-both-a-case-of-diagnostic-challenge
#1
Joana R Carvalho, Joana Tavares, Inês Goulart, Paula Moura Dos Santos, Emília Vitorino, Cristina Ferreira, Fátima Serejo, José Velosa
Signet ring cell carcinoma is a rare form of adenocarcinoma that predominantly affects the stomach. Signet ring cell carcinoma originated from the ileum is extremely rare and the prognosis is poor. We present a case of small bowel obstruction with features suggesting Crohn disease of the ileum. The symptoms were chronic diarrhea and abdominal pain with a family history of inflammatory bowel disease. The patient underwent surgery and histopathology revealed both aspects of signet ring cell carcinoma and Crohn disease of the ileum...
January 2018: GE Portuguese Journal of Gastroenterology
https://www.readbyqxmd.com/read/29447146/health-risk-behaviors-and-chronic-conditions-among-adults-with-inflammatory-bowel-disease-united-states-2015-and-2016
#2
Fang Xu, James M Dahlhamer, Emily P Zammitti, Anne G Wheaton, Janet B Croft
Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, involves chronic inflammation of the gastrointestinal tract. In 2015, an estimated 3.1 million adults in the United States had ever received a diagnosis of IBD (1). Nationally representative samples of adults with IBD have been unavailable or too small to assess relationships between IBD and other chronic conditions and health-risk behaviors (2). To assess the prevalence of health-risk behaviors and chronic conditions among adults with and without IBD, CDC aggregated survey data from the 2015 and 2016 National Health Interview Survey (NHIS)...
February 16, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29429045/evidence-based-clinical-practice-guidelines-for-inflammatory-bowel-disease
#3
REVIEW
Katsuyoshi Matsuoka, Taku Kobayashi, Fumiaki Ueno, Toshiyuki Matsui, Fumihito Hirai, Nagamu Inoue, Jun Kato, Kenji Kobayashi, Kiyonori Kobayashi, Kazutaka Koganei, Reiko Kunisaki, Satoshi Motoya, Masakazu Nagahori, Hiroshi Nakase, Fumio Omata, Masayuki Saruta, Toshiaki Watanabe, Toshiaki Tanaka, Takanori Kanai, Yoshinori Noguchi, Ken-Ichi Takahashi, Kenji Watanabe, Toshifumi Hibi, Yasuo Suzuki, Mamoru Watanabe, Kentaro Sugano, Tooru Shimosegawa
Inflammatory bowel disease (IBD) is a chronic disorder involving mainly the intestinal tract, but possibly other gastrointestinal and extraintestinal organs. Although etiology is still uncertain, recent knowledge in pathogenesis has accumulated, and novel diagnostic and therapeutic modalities have become available for clinical use. Therefore, the previous guidelines were urged to be updated. In 2016, the Japanese Society of Gastroenterology revised the previous versions of evidence-based clinical practice guidelines for ulcerative colitis (UC) and Crohn's disease (CD) in Japanese...
February 10, 2018: Journal of Gastroenterology
https://www.readbyqxmd.com/read/29391765/epidemiology-of-inflammatory-bowel-disease-in-racial-and-ethnic-migrant-groups
#4
Ravi Misra, Omar Faiz, Pia Munkholm, Johan Burisch, Naila Arebi
AIM: To summarise the current literature and define patterns of disease in migrant and racial groups. METHODS: A structured key word search in Ovid Medline and EMBASE was undertaken in accordance with PRISMA guidelines. Studies on incidence, prevalence and disease phenotype of migrants and races compared with indigenous groups were eligible for inclusion. RESULTS: Thirty-three studies met the inclusion criteria. Individual studies showed significant differences in incidence, prevalence and disease phenotype between migrants or race and indigenous groups...
January 21, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29360881/healthcare-professionals-views-of-the-experiences-of-individuals-living-with-crohn-s-disease-in-spain-a-qualitative-study
#5
Sofía García-Sanjuán, Manuel Lillo-Crespo, Miguel Richart-Martínez, Ángela Sanjuán-Quiles
Crohn's Disease (CD) in Spain lacks of a unified National Clinical Pathway and not even any early detection program and professional follow-up outpatient attention once it has been diagnosed. Little is known about the Spanish health professionals' views of the experiences of individuals living with Crohn's Disease nationwide and also about how the Spanish Health System faces this situation. A qualitative research method was conducted to explore this topic through in-depth interviews with eleven healthcare professionals, who represented different clinics treating people with CD from the province of Alicante (Spain)...
2018: PloS One
https://www.readbyqxmd.com/read/29360261/advanced-endoscopic-imaging-for-diagnosis-of-ibd-present-and-future-perspectives
#6
REVIEW
Visvakanth Sivanathan, Gian Eugenio Tontini, Markus Möhler, Peter R Galle, Helmut Neumann
Crohn's disease and ulcerative colitis are chronic inflammatory bowel diseases (IBD) causing severe damage of the luminal gastrointestinal tract. Differential diagnosis between both disease entities is sometimes awkward requiring a multifactorial pathway, including clinical and laboratory data, radiological findings, histopathology and endoscopy. Apart from disease diagnosis, endoscopy in IBD plays a major role for prediction of disease severity and extent (i.e. mucosal healing) for tailored patient management and for screening of colitis associated cancer and its precursor lesions...
January 23, 2018: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29358872/psychiatric-morbidity-after-surgery-for-inflammatory-bowel-disease-a-systematic-review
#7
Marie Strøm Zangenberg, Alaa El-Hussuna
AIM: To examine the evidence about psychiatric morbidity after inflammatory bowel disease (IBD)-related surgery. METHODS: PRISMA guidelines were followed and a protocol was published at PROSPERO (CRD42016037600). Inclusion criteria were studies describing patients with inflammatory bowel disease undergoing surgery and their risk of developing psychiatric disorder. RESULTS: Twelve studies (including 4340 patients) were eligible. All studies were non-randomized and most had high risk of bias...
December 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29324371/multiple-synchronous-adenocarcinomas-of-the-small-bowel-in-a-young-patient-a-case-report
#8
Cristián Cavalla, Federico Oppliger, Giancarlo Schiappacasse, Rodrigo Valderrama, Adriana Castiblanco, Sonia Margarit
INTRODUCTION: Adenocarcinoma of the small bowel is a rare neoplasm presented usually in elder patients as a single tumor. Its presentation as multiple tumors and in young patients is exceptional and there aren't any guidelines to orient its therapy. PRESENTATION OF CASE: We present the rare case of a sixteen-year-old woman that presents to the emergency department with an intussusception due to a small bowel tumor. The resected specimen showed multiple adenocarcinomas...
December 27, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29315147/nonmelanoma-skin-cancer-risk-in-patients-with-inflammatory-bowel-disease-undergoing-thiopurine-therapy-a-systematic-review-of-the-literature
#9
Joshua W Hagen, Melissa A Pugliano-Mauro
BACKGROUND: Azathioprine and 6-mercaptopurine (thiopurines) are common adjunct treatments for inflammatory bowel disease (IBD). Although thiopurine therapy in organ transplant recipients is known to increase nonmelanoma skin cancers (NMSCs), dermatologic literature yields less data regarding NMSC risk of thiopurine use in IBD. OBJECTIVE: The aim of this study was to systematically review current literature on NMSC risk in patients with IBD using thiopurine therapy...
January 8, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29307029/imaging-of-the-small-intestine-in-crohn-s-disease-joint-position-statement-of-the-indian-society-of-gastroenterology-and-indian-radiological-and-imaging-association
#10
Saurabh Kedia, Raju Sharma, Govind K Makharia, Vineet Ahuja, Devendra Desai, Devasenathipathy Kandasamy, Anu Eapen, Karthik Ganesan, Uday C Ghoshal, Naveen Kalra, D Karthikeyan, Kumble Seetharama Madhusudhan, Mathew Philip, Amarender Singh Puri, Sunil Puri, Saroj K Sinha, Rupa Banerjee, Shobna Bhatia, Naresh Bhat, Sunil Dadhich, G K Dhali, B D Goswami, S K Issar, V Jayanthi, S P Misra, Sandeep Nijhawan, Pankaj Puri, Avik Sarkar, S P Singh, Anshu Srivastava, Philip Abraham, B S Ramakrishna
The Indian Society of Gastroenterology (ISG) Task Force on Inflammatory Bowel Disease and the Indian Radiological and Imaging Association (IRIA) developed combined ISG-IRIA evidence-based best-practice guidelines for imaging of the small intestine in patients with suspected or known Crohn's disease. These 29 position statements, developed through a modified Delphi process, are intended to serve as reference for teaching, clinical practice, and research.
January 6, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29304214/biofilms-and-beyond-expanding-echinocandin-utility
#11
Emily L Larkin, Sharvari Dharmaiah, Mahmoud A Ghannoum
Echinocandins have been in use for over 15 years, starting with the first approval in 2001. Current trends, such as increasing resistance to fluconazole and shifts toward non-albicans spp. of Candida, suggest a growing role for echinocandins, as reflected by recent (2016) updates to guidelines that recommend echinocandins as first-line treatment for candidaemia. The efficacy, tolerability, and safety of echinocandins and their target site of action (1,3-β-d-glucan synthesis) have prompted research into potential new uses, such as for treatment of biofilm infections, MDR Candida auris and dermatophytes...
January 1, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29302504/characteristics-of-upper-gastrointestinal-tract-involvement-in-korean-pediatric-crohn-s-disease-a-multicenter-study
#12
Ji Hyoung Park, Hye Na Nam, Ji-Hyuk Lee, Jeana Hong, Dae Yong Yi, Eell Ryoo, In Sang Jeon, Hann Tchah
Purpose: Crohn's disease (CD) can involve any site of the gastrointestinal tract (GIT). However, the characteristics of upper GIT involvement in CD are unclear, especially in the Eastern pediatric population. This study aimed to estimate the prevalence of upper GIT involvement and identify the clinical features of Korean children with CD. Methods: This was a retrospective multicenter cohort study that included 52 pediatric patients with CD who underwent esophagogastroduodenoscopy and biopsy...
December 2017: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/29282629/inflammatory-bowel-disease-is-not-a-contraindication-for-bariatric-surgery
#13
Stephanie Aelfers, Ignace M C Janssen, Edo O Aarts, Carolijn Smids, Marcel J Groenen, Frits J Berends
BACKGROUND: Inflammatory bowel diseases (IBD) are listed as a contraindication for bariatric surgery in various guidelines due to a theoretical higher complication risk. Therefore, little is known about safety and efficacy of bariatric surgery in IBD patients. AIM: We assessed the safety and efficacy of bariatric surgery and postoperative quality of life (QoL) in IBD patients. SETTING: The study was conducted in a large peripheral hospital in the Netherlands...
December 27, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29249271/evaluation-and-comparison-of-capsule-endoscopy-scores-for-assessment-of-inflammatory-activity-of-small-bowel-in-crohn-s-disease
#14
Ana Ponte, Rolando Pinho, Adélia Rodrigues, Joana Silva, Jaime Rodrigues, Mafalda Sousa, João Carvalho
INTRODUCTION: Capsule endoscopy (CE) has the highest sensitivity in the evaluation of small-bowel mucosa in Crohn's disease (CD). Recent guidelines recommend the use of validated CE scores to assess small-bowel inflammatory activity in CD. Lewis score (LS) and Capsule Endoscopy Crohn's Disease Activity Index (CECDAI) are the currently available validated scores, but comparative studies are scarce. Moreover, correlation of these endoscopic scores with biomarkers and clinical activity is lacking...
December 14, 2017: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/29240002/practices-attitudes-and-knowledge-about-crohn-s-disease-and-smoking-cessation-among-gastroenterologists
#15
Benjamin Nulsen, Bruce E Sands, Brijen J Shah, Ryan C Ungaro
OBJECTIVE: Cigarette smoking is one of the most important, modifiable environmental factors in Crohn's disease (CD) and screening for tobacco use is an official recommendation and quality measure in the care of CD patients. The objective of this study was to learn more about gastroenterologists' practices, opinions, and knowledge in this area. PATIENTS AND METHODS: A 15 question survey was sent through email to two national gastroenterology distribution lists. Questions were written in multiple choice formats and were designed to collect information about gastroenterologists' practices, attitudes, and knowledge regarding smoking cessation in CD patients...
December 12, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29186643/-s2k-guideline-gastrointestinal-bleeding-guideline-of-the-german-society-of-gastroenterology-dgvs
#16
(no author information available yet)
No abstract text is available yet for this article.
September 2017: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/29152405/association-of-mir-146-rs2910164-mir-196a-rs11614913-mir-221-rs113054794-and-mir-224-rs188519172-polymorphisms-with-anti-tnf-treatment-response-in-a-greek-population-with-crohn-s-disease
#17
Ioannis Papaconstantinou, Christina Kapizioni, Evangelia Legaki, Elena Xourgia, George Karamanolis, Antonios Gklavas, Maria Gazouli
AIM: To investigate the correlation between rs2910164, rs11 614913, rs113054794, and rs188519172 polymorphisms and response to anti-TNF treatment in patients with Crohn's disease (CD). METHODS: One hundred seven patients with CD based on standard clinical, endoscopic, radiological, and pathological criteria were included in the study. They all received infliximab or adalimumab intravenously or subcutaneously at standard induction doses as per international guidelines...
November 6, 2017: World Journal of Gastrointestinal Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29147878/knowledge-gaps-in-the-management-of-postoperative-crohn-s-disease-a-us-national-survey
#18
Vu Q Nguyen, Jessica L Mays, Marissa Lang, Yingxing Wu, Themistocles Dassopoulos, Miguel Regueiro, Alan Moss, Deborah D Proctor, Dario Sorrentino
BACKGROUND: Postoperative recurrence (POR) of Crohn's disease (CD) is common. Guidelines on POR management have recently been issued, but clinical practice may vary. AIMS: To examine the current clinical practice of POR management in the USA METHODS: A web-based survey was sent to all members of the American Gastroenterological Association and the American College of Gastroenterology. The survey consisted of multiple-choice questions with clinical scenarios to assess how participants manage POR...
November 17, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29142516/outcomes-of-limited-period-of-adalimumab-treatment-in-moderate-to-severe-crohn-s-disease-patients-taiwan-society-of-inflammatory-bowel-disease-study
#19
Wei-Chen Lin, Jen-Wei Chou, Hsu-Heng Yen, Wen-Hung Hsu, Hung-Hsin Lin, Jen-Kou Lin, Chiao-Hsiung Chuang, Tien-Yu Huang, Horng-Yuan Wang, Shu-Chen Wei, Jau-Min Wong
Background/Aims: In Taiwan, due to budget limitations, the National Health Insurance only allows for a limited period of biologics use in treating moderate to severe Crohn's disease (CD). We aimed to access the outcomes of CD patients following a limited period use of biologics, specifically focusing on the relapse rate and remission duration; also the response rate to second use when applicable. Methods: This was a multicenter, retrospective, observational study and we enrolled CD patients who had been treated with adalimumab (ADA) according to the insurance guidelines from 2009 to 2015...
October 2017: Intestinal Research
https://www.readbyqxmd.com/read/29141269/-practice-guideline-autoimmune-liver-diseases-awmf-reg-no-021-27
#20
(no author information available yet)
The guideline was created under the leadership of the DGVS and with participation of neighbouring scientific societies and is intended as a practical aid for the diagnosis and therapy of autoimmune liver diseases. The aim is to represent the current state of science, promote the recognition of the disease and improve the treatment of patients.
November 2017: Zeitschrift Für Gastroenterologie
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